Text Compare
Produced: 1/17/2012 9:55:38 AM
   
Mode:  Differences, Ignoring Unimportant  
Left base folder: C:\Users\aviswanathan\Downloads\2.5 Project\xsd-2.5.0-final  
Right base folder: C:\Users\aviswanathan\Downloads\2.5 Project\xsd-2.4.4-baseline  

   
File: TCGA_BCR.Auxiliary_Data.xsd  

4	<xs:schema elementFormDefault="qualified" version="2.5.0"	<>	4	<xs:schema elementFormDefault="qualified" version="2.4.4"
6	xmlns:utility="http://tcga.nci/bcr/xml/utility/2.5"	<>	6	xmlns:utility="http://tcga.nci/bcr/xml/utility/2.4"
7	xmlns:admin="http://tcga.nci/bcr/xml/administration/2.5"		7	xmlns:admin="http://tcga.nci/bcr/xml/administration/2.4"
8	xmlns:shared="http://tcga.nci/bcr/xml/clinical/shared/2.5"		8	xmlns:shared="http://tcga.nci/bcr/xml/clinical/shared/2.4"
9	xmlns="http://tcga.nci/bcr/xml/auxdata/2.5"		9	xmlns="http://tcga.nci/bcr/xml/auxdata/2.4"
10	targetNamespace="http://tcga.nci/bcr/xml/auxdata/2.5"		10	targetNamespace="http://tcga.nci/bcr/xml/auxdata/2.4"
27	<xs:import namespace="http://tcga.nci/bcr/xml/utility/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/utility/2.5/TCGA_BCR.Utility.xsd" />	<>	27	<xs:import namespace="http://tcga.nci/bcr/xml/utility/2.4" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/utility/2.4/TCGA_BCR.Utility.xsd" />
28	<xs:import namespace="http://tcga.nci/bcr/xml/administration/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/administration/2.5/TCGA_BCR.Administration.xsd" />		28	<xs:import namespace="http://tcga.nci/bcr/xml/administration/2.4" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/administration/2.4/TCGA_BCR.Administration.xsd" />
29	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/shared/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/shared/2.5/TCGA_BCR.Shared_Clinical_Elements.xsd" />		29	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/shared/2.4" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/shared/2.4/TCGA_BCR.Shared_Clinical_Elements.xsd" />
37	<xs:attribute name="schemaVersion" type="xs:decimal" use="required" fixed="2.5"/>	<>	37	<xs:attribute name="schemaVersion" type="xs:decimal" use="required" fixed="2.4"/>

   
File: TCGA_BCR.Biospecimen.xsd  

3	<xs:schema xmlns:xs="http://www.w3.org/2001/XMLSchema" xmlns:utility="http://tcga.nci/bcr/xml/utility/2.5" xmlns:admin="http://tcga.nci/bcr/xml/administration/2.5" xmlns:shared="http://tcga.nci/bcr/xml/clinical/shared/2.5" xmlns:cqcf="http://tcga.nci/bcr/xml/clinical/cqcf/2.5" xmlns="http://tcga.nci/bcr/xml/biospecimen/2.5" xmlns:jaxb="http://java.sun.com/xml/ns/jaxb" targetNamespace="http://tcga.nci/bcr/xml/biospecimen/2.5" elementFormDefault="qualified" version="2.5.0" jaxb:version="1.0">	<>	3	<xs:schema xmlns:xs="http://www.w3.org/2001/XMLSchema" xmlns:utility="http://tcga.nci/bcr/xml/utility/2.4" xmlns:admin="http://tcga.nci/bcr/xml/administration/2.4" xmlns:shared="http://tcga.nci/bcr/xml/clinical/shared/2.4" xmlns="http://tcga.nci/bcr/xml/biospecimen/2.4" xmlns:jaxb="http://java.sun.com/xml/ns/jaxb" targetNamespace="http://tcga.nci/bcr/xml/biospecimen/2.4" elementFormDefault="qualified" version="2.4.4" jaxb:version="1.0">
15	<xs:import namespace="http://tcga.nci/bcr/xml/utility/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/utility/2.5/TCGA_BCR.Utility.xsd"/>	<>	15	<xs:import namespace="http://tcga.nci/bcr/xml/utility/2.4" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/utility/2.4/TCGA_BCR.Utility.xsd"/>
16	<xs:import namespace="http://tcga.nci/bcr/xml/administration/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/administration/2.5/TCGA_BCR.Administration.xsd"/>		16	<xs:import namespace="http://tcga.nci/bcr/xml/administration/2.4" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/administration/2.4/TCGA_BCR.Administration.xsd"/>
17	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/shared/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/shared/2.5/TCGA_BCR.Shared_Clinical_Elements.xsd"/>		17	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/shared/2.4" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/shared/2.4/TCGA_BCR.Shared_Clinical_Elements.xsd"/>
18	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/cqcf/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/cqcf/2.5/TCGA_BCR.CQCF.xsd"/>
25	<xs:attribute name="schemaVersion" type="xs:decimal" use="required" fixed="2.5"/>	<>	24	<xs:attribute name="schemaVersion" type="xs:decimal" use="required" fixed="2.4"/>
44	<xs:element ref="cqcf:biospecimen_cqcf"/>	+-
83	<xs:element ref="NCNNCT_OthMethONSP"/>	<>	81	<xs:element ref="other_method_of_sample_procurement"/>
93	<xs:element ref="diagnostic_slides"/>	<>	91	<xs:element ref="ffpe_slide_uuid"/>
		-+	114	<xs:enumeration value="40"/>
		-+	164	<xs:enumeration value="Xenograft cell-line derived"/>
453	<xs:element ref="LCE"/>	+-
		-+	685	<xs:element ref="biospecimen_barcode_bottom"/>
946	<xs:element name="LCE">	+-
947	<xs:complexType>
948	<xs:simpleContent>
949	<xs:restriction base="utility:common_res_attributes">
950	<xs:enumeration value=""/>
951	<xs:enumeration value="LCE"/>
952	<xs:attribute name="cde" type="xs:string" default="3251491"/>
953	<xs:attribute name="xsd_ver" type="xs:string" default="1.8"/>
954	</xs:restriction>
955	</xs:simpleContent>
956	</xs:complexType>
957	</xs:element>
1451	<xs:element ref="primary_or_metastatic_status" minOccurs="0"/>	<>	1439	<xs:element ref="primary_ormetastatic_status" minOccurs="0"/>
1462	<xs:element name="primary_or_metastatic_status">	<>	1450	<xs:element name="primary_ormetastatic_status">
1551	<xs:element name="NCNNCT_OthMethONSP">	<>	1539	<xs:element name="other_method_of_sample_procurement">
1623	<xs:element name="diagnostic_slides">	+-
1624	<xs:complexType>
1625	<xs:sequence>
1626	<xs:element ref="ffpe_slide_uuid" minOccurs="0" maxOccurs="unbounded"/>
1627	</xs:sequence>
1628	</xs:complexType>
1629	</xs:element>

   
File: TCGA_BCR.BLCA_Clinical.xsd  

4	<xs:schema elementFormDefault="qualified" version="2.5.0"	<>	4	<xs:schema elementFormDefault="qualified" version="2.4.4"
6	xmlns:utility="http://tcga.nci/bcr/xml/utility/2.5"	<>	6	xmlns:utility="http://tcga.nci/bcr/xml/utility/2.4"
7	xmlns:admin="http://tcga.nci/bcr/xml/administration/2.5"		7	xmlns:admin="http://tcga.nci/bcr/xml/administration/2.4"
8	xmlns:shared="http://tcga.nci/bcr/xml/clinical/shared/2.5"		8	xmlns:shared="http://tcga.nci/bcr/xml/clinical/shared/2.4"
9	xmlns:rad="http://tcga.nci/bcr/xml/clinical/radiation/2.5"		9	xmlns:rad="http://tcga.nci/bcr/xml/clinical/radiation/2.4"
10	xmlns:rx="http://tcga.nci/bcr/xml/clinical/pharmaceutical/2.5"		10	xmlns:rx="http://tcga.nci/bcr/xml/clinical/pharmaceutical/2.4"
11	xmlns:cqcf="http://tcga.nci/bcr/xml/clinical/cqcf/2.5"
12	xmlns:follow_up_v2.0="http://tcga.nci/bcr/xml/clinical/blca/followup/2.5/2.0"
13	xmlns="http://tcga.nci/bcr/xml/clinical/blca/2.5"		11	xmlns="http://tcga.nci/bcr/xml/clinical/blca/2.4"
14	targetNamespace="http://tcga.nci/bcr/xml/clinical/blca/2.5"		12	targetNamespace="http://tcga.nci/bcr/xml/clinical/blca/2.4"
31	<xs:import namespace="http://tcga.nci/bcr/xml/utility/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/utility/2.5/TCGA_BCR.Utility.xsd" />	<>	28	<xs:import namespace="http://tcga.nci/bcr/xml/utility/2.4" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/utility/2.4/TCGA_BCR.Utility.xsd" />
32	<xs:import namespace="http://tcga.nci/bcr/xml/administration/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/administration/2.5/TCGA_BCR.Administration.xsd" />		29	<xs:import namespace="http://tcga.nci/bcr/xml/administration/2.4" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/administration/2.4/TCGA_BCR.Administration.xsd" />
33	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/shared/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/shared/2.5/TCGA_BCR.Shared_Clinical_Elements.xsd" />		30	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/shared/2.4" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/shared/2.4/TCGA_BCR.Shared_Clinical_Elements.xsd" />
34	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/radiation/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/radiation/2.5/TCGA_BCR.Radiation.xsd" />		31	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/radiation/2.4" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/radiation/2.4/TCGA_BCR.Radiation.xsd" />
35	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/pharmaceutical/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/pharmaceutical/2.5/TCGA_BCR.Pharmaceutical.xsd" />		32	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/pharmaceutical/2.4" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/pharmaceutical/2.4/TCGA_BCR.Pharmaceutical.xsd" />
36	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/cqcf/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/cqcf/2.5/TCGA_BCR.CQCF.xsd" />
37	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/blca/shared/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/blca/shared/2.5/TCGA_BCR.BLCA_Clinical_Shared_Datatypes.xsd" />
38	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/blca/followup/2.5/2.0" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/blca/followup/2.5/TCGA_BCR.BLCA_Clinical_FollowUp_v2.0.xsd" />
47	<xs:attribute name="schemaVersion" type="xs:decimal" use="required" fixed="2.5"/>	<>	41	<xs:attribute name="schemaVersion" type="xs:decimal" use="required" fixed="2.4"/>
54	<xs:element ref="shared:tissue_source_site" />	+-
55	<xs:element ref="shared:patient_id" />
56	<xs:element ref="shared:bcr_patient_barcode" />
57	<xs:element ref="shared:bcr_patient_uuid" />
58	<xs:element ref="shared:informed_consent_verified" />
59	<xs:element ref="shared:icd_o_3_site" />
60	<xs:element ref="shared:icd_o_3_histology" />
61	<xs:element ref="shared:icd_10" />
63	<xs:choice>	+-
64	<xs:sequence>
65	<xs:element ref="shared:day_of_form_completion" />
66	<xs:element ref="shared:month_of_form_completion" />
67	<xs:element ref="shared:year_of_form_completion" />
68	</xs:sequence>
70	<xs:element ref="shared:days_to_form_completion" />	+-
71	</xs:choice>
73	<xs:element ref="tissue_prospective_collection_indicator" />	+-
74	<xs:element ref="tissue_retrospective_collection_indicator" />
		-+	63	<xs:element ref="shared:vital_status" />
			64	<xs:element ref="shared:person_neoplasm_cancer_status" />
93	<xs:element ref="shared:vital_status" />	+-
106	<xs:annotation>	+-
107	<xs:documentation xml:lang="en">
108	The Date for Last Known Alive was DEPRECATED.  It
109	was last placed on the TCGA Clinical Form 1.11.
110	</xs:documentation>
111	</xs:annotation>
122	<xs:choice>	+-
123	<xs:sequence>
124	<xs:element ref="shared:day_of_death" />
125	<xs:element ref="shared:month_of_death" />
126	<xs:element ref="shared:year_of_death" />
127	</xs:sequence>
129	<xs:element ref="shared:days_to_death" />	+-
130	</xs:choice>
132	<xs:element ref="shared:person_neoplasm_cancer_status" />	+-
133	<xs:element ref="person_occupation_description_text" />
134	<xs:element ref="occupation_primary_job" />
135	<xs:element ref="chemical_exposure_text" />
136	<xs:element ref="person_primary_industry_text" />
137	<xs:element ref="person_occupation_years_number" />
138	<xs:element ref="tobacco_smoking_history_indicator" />
139	<xs:element ref="age_began_smoking_in_years" />
140	<xs:element ref="shared:stopped_smoking_year" />
141	<xs:element ref="shared:number_pack_years_smoked" />
142	<xs:element ref="blood_relative_cancer_history_list" />
144	<xs:element ref="shared:tumor_histologic_subtype" />	+-
145	<xs:element ref="diagnosis_subtype" />
146	<xs:element ref="bladder_tumor_histologic_who_2004_grade" />
147	<xs:element ref="shared:anatomic_organ_subdivision" />
		-+	103	<xs:element ref="shared:radiation_therapy" />
			104	<xs:element ref="shared:additional_pharmaceutical_therapy" />
		-+	106	<xs:choice>
			107	<xs:sequence>
			108	<xs:element ref="shared:day_of_death" />
			109	<xs:element ref="shared:month_of_death" />
			110	<xs:element ref="shared:year_of_death" />
			111	</xs:sequence>
		-+	113	<xs:element ref="shared:days_to_death" />
			114	</xs:choice>
		-+	116	<xs:choice>
			117	<xs:sequence>
			118	<xs:element ref="shared:day_of_new_tumor_event_after_initial_treatment" />
			119	<xs:element ref="shared:month_of_new_tumor_event_after_initial_treatment" />
			120	<xs:element ref="shared:year_of_new_tumor_event_after_initial_treatment" />
			121	</xs:sequence>
		-+	123	<xs:element ref="shared:days_to_new_tumor_event_after_initial_treatment" />
			124	</xs:choice>
		-+	126	<xs:element ref="shared:additional_surgery_locoregional_procedure" />
		-+	128	<xs:choice>
			129	<xs:sequence>
			130	<xs:element ref="shared:day_of_additional_surgery_metastatic_procedure" />
			131	<xs:element ref="shared:month_of_additional_surgery_metastatic_procedure" />
			132	<xs:element ref="shared:year_of_additional_surgery_metastatic_procedure" />
			133	</xs:sequence>
		-+	135	<xs:element ref="shared:days_to_additional_surgery_metastatic_procedure" />
			136	</xs:choice>
		-+	138	<xs:element ref="shared:additional_radiation_therapy" />
		-+	141	<xs:element ref="shared:bcr_patient_barcode" />
			142	<xs:element ref="shared:tissue_source_site" />
			143	<xs:element ref="shared:patient_id" />
			144	<xs:element ref="shared:bcr_patient_uuid" />
			145	<xs:element ref="shared:informed_consent_verified" />
			146	<xs:element ref="shared:icd_o_3_site" />
			147	<xs:element ref="shared:icd_o_3_histology" />
			148	<xs:element ref="shared:icd_10" />
		-+	150	<xs:element ref="tissue_prospective_collection_indicator" />
			151	<xs:element ref="tissue_retrospective_collection_indicator" />
			152	<xs:element ref="person_occupation_description_text" />
			153	<xs:element ref="occupation_primary_job" />
			154	<xs:element ref="chemical_exposure_text" />
			155	<xs:element ref="person_primary_industry_text" />
			156	<xs:element ref="person_occupation_years_number" />
			157	<xs:element ref="patient_smoking_history_category" />
			158	<xs:element ref="age_began_smoking_in_years" />
			159	<xs:element ref="stopped_smoking_year" />
			160	<xs:element ref="person_cigarette_smoking_history_pack_year_value" />
			161	<xs:element ref="blood_relative_cancer_history_list" />
			162	<xs:element ref="tumor_histologic_subtype_type" />
			163	<xs:element ref="specimen_histologic_type_type_histologictype" />
			164	<xs:element ref="bladder_tumor_histologic_who_2004_grade" />
			165	<xs:element ref="anatomic_site_location_descriptor" />
165	<xs:element ref="shared:primary_lymph_node_presentation_assessment">	+-
166	<xs:annotation>
167	<xs:documentation xml:lang="en">
168	This item was first introduced in version 2.04 of the TCGA Clinical Data Form
169	</xs:documentation>
170	</xs:annotation>
171	</xs:element>
173	<xs:element ref="shared:lymph_node_examined_count" />	<>	168	<xs:element ref="lymph_node_examined_count" />
174	<xs:element ref="shared:number_of_lymphnodes_positive_by_he" />		169	<xs:element ref="positive_finding_lymph_node_hematoxylin_and_eosin_staining_microscopy_count" />
177	<xs:element ref="shared:lymphovascular_invasion_present" />	<>	172	<xs:element ref="tumor_lymphovascular_invasion_ind" />
179	<xs:element ref="shared:ajcc_cancer_staging_handbook_edition" minOccurs="0" maxOccurs="1">	<>	173	<xs:element ref="shared:ajcc_cancer_staging_handbook_edition" minOccurs="0" maxOccurs="1" />
180	<xs:annotation>
181	<xs:documentation xml:lang="en">
182	This item was first introduced in version 2.04 of the TCGA Clinical Data Form
183	</xs:documentation>
184	</xs:annotation>
185	</xs:element>
188	<xs:element ref="shared:ajcc_tumor_stage_code" />	<>	175	<xs:element ref="bladder_carcinoma_pathologic_t_stage" />
189	<xs:element ref="shared:ajcc_neoplasm_disease_lymph_node_stage" />		176	<xs:element ref="bladder_carcinoma_pathologic_n_stage" />
190	<xs:element ref="shared:ajcc_cancer_metastasis_stage_code" />		177	<xs:element ref="bladder_carcinoma_pathologic_m_stage" />
191	<xs:element ref="malignant_neoplasm_metastatic_involvement_sites" />		178	<xs:element ref="bladder_malignant_neoplasm_metastatic_involvement_sites" />
192	<xs:element ref="other_metastatic_involvement_anatomic_site" />		179	<xs:element ref="bladder_carcinoma_other_metastatic_involvement_anatomic_site_text" />
193	<xs:element ref="shared:ajcc_neoplasm_disease_stage" />		180	<xs:element ref="bladder_carcinoma_clinical_stage" />
197	<xs:element ref="shared:karnofsky_performance_score" />	<>	184	<xs:element ref="karnofsky_performance_status_score" />
198	<xs:element ref="shared:eastern_cancer_oncology_group" />		185	<xs:element ref="performance_status_assessment_eastern_cooperative_oncology_group_scale" />
200	<xs:element ref="follow_ups" />	<>
201	<xs:element ref="rx:drugs" />
202	<xs:element ref="rad:radiations" />		186	<xs:element ref="primary_therapy_outcome_success_type" />
203	<xs:element ref="clinical_cqcf" />
204	</xs:sequence>
205	</xs:complexType>
206	</xs:element>
208	<xs:element name="follow_ups">	<>	187	<xs:element ref="new_neoplasm_event_type" />
209	<xs:annotation>
210	<xs:documentation xml:lang="en">
211	We are using namespaces and version numbers to distinguish one version of followup from another.
212	</xs:documentation>
213	</xs:annotation>
214	<xs:complexType>
215	<xs:sequence>
216	<xs:element ref="follow_up_v2.0:follow_up_v2.0" minOccurs="0" maxOccurs="unbounded" />		188	<xs:element ref="new_neoplasm_event_occurrence_anatomic_site" />
217	</xs:sequence>
218	</xs:complexType>
219	</xs:element>
221	<xs:element name="clinical_cqcf">	<>
222	<xs:complexType>
223	<xs:sequence>
224	<xs:element ref="shared:anatomic_organ_subdivision"/>		189	<xs:element ref="new_neoplasm_occurrence_anatomic_site_text" />
225	<xs:element ref="cqcf:consent_or_death_status"/>		190	<xs:element ref="additional_treatment_completion_success_outcome_type" />
228	<xs:choice>	+-
230	<xs:element ref="cqcf:day_of_consent"/>	<>	194	<xs:element ref="shared:day_of_form_completion" />
231	<xs:element ref="cqcf:month_of_consent"/>		195	<xs:element ref="shared:month_of_form_completion" />
232	<xs:element ref="cqcf:year_of_consent"/>		196	<xs:element ref="shared:year_of_form_completion" />
235	<xs:element ref="cqcf:days_to_consent"/>	+-
236	</xs:choice>
238	<xs:choice>	<>
239	<xs:sequence>
240	<xs:element ref="shared:day_of_death"/>
241	<xs:element ref="shared:month_of_death"/>		199	<xs:element ref="shared:days_to_form_completion" />
242	<xs:element ref="shared:year_of_death"/>
243	</xs:sequence>
245	<xs:element ref="shared:days_to_death"/>	+-
246	</xs:choice>
249	<xs:element ref="cqcf:diagnosis_subtype"/>	<>	202	<xs:element ref="rx:drugs" />
250	<xs:element ref="shared:prior_diagnosis"/>		203	<xs:element ref="rad:radiations" />
251	<xs:element ref="cqcf:history_of_neoadjuvant_treatment"/>
252	<xs:element ref="cqcf:normal_tissue_anatomic_site"/>
253	<xs:element ref="cqcf:normal_tissue_proximity"/>
254	<xs:element ref="cqcf:tumor_focality"/>
255	<xs:element ref="cqcf:tumor_type"/>
256	<xs:element ref="cqcf:other_diagnosis"/>
257	<xs:element ref="cqcf:histological_subtype" minOccurs="0"/>
258	<xs:element ref="cqcf:other_anatomic_site" minOccurs="0"/>
259	<xs:element ref="cqcf:country"/>
345	<xs:extension base="utility:number_or_null">	<>	289	<xs:extension base="xs:decimal">
355	<xs:element name="tobacco_smoking_history_indicator" nillable="true">	<>	299	<xs:element name="patient_smoking_history_category" nillable="true">
375	<xs:extension base="utility:number_or_null">	<>	319	<xs:extension base="xs:decimal">
		-+	329	<xs:element name="stopped_smoking_year" nillable="true">
			330	<xs:complexType>
			331	<xs:simpleContent>
			332	<xs:extension base="xs:decimal">
			333	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			334	<xs:attribute name="cde" type="xs:string" default="2228610" />
			335	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			336	<xs:attribute name="tier" type="xs:string" default="2" />
			337	</xs:extension>
			338	</xs:simpleContent>
			339	</xs:complexType>
			340	</xs:element>
		-+	342	<xs:element name="person_cigarette_smoking_history_pack_year_value" nillable="true">
			343	<xs:complexType>
			344	<xs:simpleContent>
			345	<xs:extension base="xs:decimal">
			346	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			347	<xs:attribute name="cde" type="xs:string" default="2955385" />
			348	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			349	<xs:attribute name="tier" type="xs:string" default="2" />
			350	</xs:extension>
			351	</xs:simpleContent>
			352	</xs:complexType>
			353	</xs:element>
407	<xs:enumeration value="Brother" />	<>	377	<xs:enumeration value="Mother" />
408	<xs:enumeration value="Child" />
410	<xs:enumeration value="Grandfather" />	+-
		<>	380	<xs:enumeration value="Grandfather" />
412	<xs:enumeration value="Mother" />		381	<xs:enumeration value="Brother" />
		-+	383	<xs:enumeration value="Child" />
		-+	399	<xs:enumeration value="CNS" />
			400	<xs:enumeration value="CNS-Glioblastoma" />
			401	<xs:enumeration value="CNS-Medulloblastoma" />
		-+	404	<xs:enumeration value="Breast-LCIS" />
			405	<xs:enumeration value="Breast-DCIS" />
		<>	408	<xs:enumeration value="Cervix-Squamous Cell Carcinoma" />
433	<xs:enumeration value="CNS" />		409	<xs:enumeration value="Cervix-Adenocarcinoma" />
442	<xs:enumeration value="Head/Face/Neck" />	<>	418	<xs:enumeration value="HeadFaceNeck" />
		-+	423	<xs:enumeration value="Leukemia-acute lymphocytic leukemia" />
			424	<xs:enumeration value="Leukemia-acute monocytic leukemia" />
			425	<xs:enumeration value="Leukemia-chronic lymphocytic leukemia" />
			426	<xs:enumeration value="Leukemia-chronic monocytic leukemia" />
			427	<xs:enumeration value="Leukemia-hairy cell leukemia" />
		-+	439	<xs:enumeration value="Ovary-Germ Cell" />
			440	<xs:enumeration value="Ovary-Epithelial" />
			441	<xs:enumeration value="Ovary-Stromal" />
465	<xs:enumeration value="Skin-Basal Cell Carcinoma" />	<>	449	<xs:enumeration value="Sarcoma-Ewings" />
			450	<xs:enumeration value="Sarcoma-Osteo" />
			451	<xs:enumeration value="Skin-NOS" />
		-+	453	<xs:enumeration value="Skin-Basal Cell Carcinoma" />
		-+	457	<xs:enumeration value="Thyroid-Follicular" />
			458	<xs:enumeration value="Thyroid-Medullary" />
			459	<xs:enumeration value="Thyroid-Papillary" />
		-+	461	<xs:enumeration value="Uterine-Papillary" />
			462	<xs:enumeration value="Uterine-Serous" />
			463	<xs:enumeration value="Uterine-PapillarySerous" />
		-+	475	<xs:element name="tumor_histologic_subtype_type" nillable="true">
			476	<xs:complexType mixed="true">
			477	<xs:simpleContent>
			478	<xs:restriction base="utility:clinical_res_attributes">
			479	<xs:enumeration value="" />
			480	<xs:enumeration value="Papillary renal cell carcinoma" />
			481	<xs:enumeration value="Squamous cell carcinoma" />
			482	<xs:enumeration value="Adenocarcinoma" />
			483	<xs:enumeration value="Cystadenocarcinoma" />
			484	<xs:enumeration value="Glioblastoma multiforme" />
			485	<xs:enumeration value="Mixed Histology" />
			486	<xs:enumeration value="Infiltrating Lobular" />
			487	<xs:enumeration value="Infiltrating Carcinoma NOS" />
			488	<xs:enumeration value="Muscle invasive urothelial carcinoma" />
			489	<xs:attribute name="cde" type="xs:string" default="2831122" />
			490	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			491	<xs:attribute name="tier" type="xs:string" default="1" />
			492	</xs:restriction>
			493	</xs:simpleContent>
			494	</xs:complexType>
			495	</xs:element>
482	<xs:element name="diagnosis_subtype" nillable="true">	<>	497	<xs:element name="specimen_histologic_type_type_histologictype" nillable="true">
487	<xs:enumeration value="Non-Papillary" />	+-
		-+	503	<xs:enumeration value="Non-Papillary" />
504	<xs:enumeration value="Papilloma" />	+-
		-+	520	<xs:enumeration value="Papilloma" />
		-+	524	</xs:restriction>
			525	</xs:simpleContent>
			526	</xs:complexType>
			527	</xs:element>
		-+	529	<xs:element name="anatomic_site_location_descriptor" nillable="true">
			530	<xs:complexType mixed="true">
			531	<xs:simpleContent>
			532	<xs:restriction base="utility:clinical_res_attributes">
			533	<xs:enumeration value="" />
			534	<xs:enumeration value="Bladder, NOS" />
			535	<xs:enumeration value="Wall, Lateral" />
			536	<xs:enumeration value="Wall, Anterior" />
			537	<xs:enumeration value="Wall, NOS" />
			538	<xs:enumeration value="Wall, Posterior" />
			539	<xs:enumeration value="Trigone" />
			540	<xs:enumeration value="Neck" />
			541	<xs:enumeration value="Dome" />
			542	<xs:attribute name="cde" type="xs:string" default="2008006" />
			543	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			544	<xs:attribute name="tier" type="xs:string" default="1" />
		-+	558	</xs:extension>
			559	</xs:simpleContent>
			560	</xs:complexType>
			561	</xs:element>
		-+	563	<xs:element name="lymph_node_examined_count" nillable="true">
			564	<xs:complexType>
			565	<xs:simpleContent>
			566	<xs:extension base="xs:integer">
			567	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			568	<xs:attribute name="cde" type="xs:string" default="3" />
			569	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
			570	<xs:attribute name="tier" type="xs:string" default="2" />
			571	</xs:extension>
			572	</xs:simpleContent>
			573	</xs:complexType>
			574	</xs:element>
		-+	576	<xs:element name="positive_finding_lymph_node_hematoxylin_and_eosin_staining_microscopy_count" nillable="true">
			577	<xs:complexType>
			578	<xs:simpleContent>
			579	<xs:extension base="xs:integer">
			580	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			581	<xs:attribute name="cde" type="xs:string" default="3086388" />
			582	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
			583	<xs:attribute name="tier" type="xs:string" default="2" />
		-+	607	<xs:enumeration value="Unknown" />
547	<xs:enumeration value="Unknown" />	+-
		-+	614	</xs:simpleContent>
			615	</xs:complexType>
			616	</xs:element>
		-+	618	<xs:element name="tumor_lymphovascular_invasion_ind" nillable="true">
			619	<xs:complexType mixed="true">
			620	<xs:simpleContent>
			621	<xs:extension base="utility:yes_or_no">
			622	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			623	<xs:attribute name="cde" type="xs:string" default="64727" />
			624	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			625	<xs:attribute name="tier" type="xs:string" default="2" />
			626	</xs:extension>
561	<xs:enumeration value="cT0" />	<>	636	<xs:enumeration value="cT4" />
562	<xs:enumeration value="cT1" />		637	<xs:enumeration value="T4b" />
563	<xs:enumeration value="cT2" />		638	<xs:enumeration value="pT3b" />
			639	<xs:enumeration value="pT3a" />
		<>	641	<xs:enumeration value="pT2b" />
			642	<xs:enumeration value="pT2a" />
565	<xs:enumeration value="cT4" />		643	<xs:enumeration value="cT2" />
566	<xs:enumeration value="cT4a" />		644	<xs:enumeration value="cT1" />
			645	<xs:enumeration value="cTis" />
568	<xs:enumeration value="cTis" />	<>	647	<xs:enumeration value="cT0" />
570	<xs:enumeration value="pT2a" />	<>
571	<xs:enumeration value="pT2b" />
572	<xs:enumeration value="pT3a" />
573	<xs:enumeration value="pT3b" />
574	<xs:enumeration value="T4b" />		649	<xs:enumeration value="cT4a" />
		-+	658	<xs:element name="bladder_carcinoma_pathologic_t_stage" nillable="true">
			659	<xs:annotation><xs:documentation>
			660	The following enumerated values have been DEPRECATED and will be removed in veresion 2.5 of the XSDs.
		-+	662	pT0, pT1, pT2, pT3, pT4, pTa, pTis, pTX, pT2a, pT2b, pT3a, pT3b, T4b, pT4a
		-+	664	</xs:documentation></xs:annotation>
			665	<xs:complexType mixed="true">
			666	<xs:simpleContent>
			667	<xs:restriction base="utility:clinical_res_attributes">
			668	<xs:enumeration value="" />
			669	<xs:enumeration value="TX" />
			670	<xs:enumeration value="T0" />
			671	<xs:enumeration value="Tis" />
			672	<xs:enumeration value="Tis (DCIS)" />
			673	<xs:enumeration value="Tis (LCIS)" />
			674	<xs:enumeration value="Tis (Paget's)" />
			675	<xs:enumeration value="T1mi" />
			676	<xs:enumeration value="T1" />
			677	<xs:enumeration value="T1a" />
			678	<xs:enumeration value="T1b" />
			679	<xs:enumeration value="T1c" />
			680	<xs:enumeration value="T2" />
			681	<xs:enumeration value="T2a" />
			682	<xs:enumeration value="T2b" />
			683	<xs:enumeration value="T2c" />
			684	<xs:enumeration value="Ta" />
			685	<xs:enumeration value="T3" />
			686	<xs:enumeration value="T3a" />
			687	<xs:enumeration value="T3b" />
			688	<xs:enumeration value="T3c" />
			689	<xs:enumeration value="T4" />
			690	<xs:enumeration value="T4a" />
			691	<xs:enumeration value="T4b" />
			692	<xs:enumeration value="T4c" />
			693	<xs:enumeration value="T4d" />
			694	<xs:enumeration value="pT0" />
			695	<xs:enumeration value="pT1" />
			696	<xs:enumeration value="pT2" />
			697	<xs:enumeration value="pT3" />
			698	<xs:enumeration value="pT4" />
			699	<xs:enumeration value="pTa" />
			700	<xs:enumeration value="pTis" />
			701	<xs:enumeration value="pTX" />
			702	<xs:enumeration value="pT2a" />
			703	<xs:enumeration value="pT2b" />
			704	<xs:enumeration value="pT3a" />
			705	<xs:enumeration value="pT3b" />
			706	<xs:enumeration value="T4b" />
			707	<xs:enumeration value="pT4a" />
			708	<xs:attribute name="cde" type="xs:string" default="3045435" />
			709	<xs:attribute name="xsd_ver" type="xs:string" default="2.4.1" />
			710	<xs:attribute name="tier" type="xs:string" default="2" />
			711	</xs:restriction>
			712	</xs:simpleContent>
			713	</xs:complexType>
			714	</xs:element>
		-+	716	<xs:element name="bladder_carcinoma_pathologic_n_stage" nillable="true">
			717	<xs:annotation><xs:documentation>
			718	The following enumerated values have been DEPRECATED and will be removed in veresion 2.5 of the XSDs.
		-+	720	pN3, pN2, pN1, pN0, pNX
		-+	722	</xs:documentation></xs:annotation>
			723	<xs:complexType mixed="true">
			724	<xs:simpleContent>
			725	<xs:restriction base="utility:clinical_res_attributes">
			726	<xs:enumeration value="" />
			727	<xs:enumeration value="NX" />
			728	<xs:enumeration value="N0" />
			729	<xs:enumeration value="N0 (i-)" />
			730	<xs:enumeration value="N0 (i+)" />
			731	<xs:enumeration value="N0 (mol-)" />
			732	<xs:enumeration value="N0 (mol+)" />
			733	<xs:enumeration value="N1" />
			734	<xs:enumeration value="N1mi" />
			735	<xs:enumeration value="N1a" />
			736	<xs:enumeration value="N1b" />
			737	<xs:enumeration value="N1bI" />
			738	<xs:enumeration value="N1bII" />
			739	<xs:enumeration value="N1bIII" />
			740	<xs:enumeration value="N1bIV" />
			741	<xs:enumeration value="N1c" />
			742	<xs:enumeration value="N2" />
			743	<xs:enumeration value="N2a" />
			744	<xs:enumeration value="N2b" />
			745	<xs:enumeration value="N3" />
			746	<xs:enumeration value="N3a" />
			747	<xs:enumeration value="N3b" />
			748	<xs:enumeration value="N3c" />
			749	<xs:enumeration value="N4" />
			750	<xs:enumeration value="pN3" />
			751	<xs:enumeration value="pN2" />
			752	<xs:enumeration value="pN1" />
			753	<xs:enumeration value="pN0" />
			754	<xs:enumeration value="pNX" />
			755	<xs:attribute name="cde" type="xs:string" default="3203106" />
			756	<xs:attribute name="xsd_ver" type="xs:string" default="2.4.1" />
			757	<xs:attribute name="tier" type="xs:string" default="2" />
			758	</xs:restriction>
			759	</xs:simpleContent>
			760	</xs:complexType>
			761	</xs:element>
		-+	763	<xs:element name="bladder_carcinoma_pathologic_m_stage" nillable="true">
			764	<xs:complexType mixed="true">
			765	<xs:simpleContent>
			766	<xs:restriction base="utility:clinical_res_attributes">
			767	<xs:enumeration value="" />
			768	<xs:enumeration value="MX" />
			769	<xs:enumeration value="M0" />
			770	<xs:enumeration value="M1" />
			771	<xs:enumeration value="M1a" />
			772	<xs:enumeration value="M1b" />
			773	<xs:enumeration value="M1c" />
			774	<xs:enumeration value="cM0 (i+)" />
			775	<xs:attribute name="cde" type="xs:string" default="3045439" />
			776	<xs:attribute name="xsd_ver" type="xs:string" default="2.4.1" />
			777	<xs:attribute name="tier" type="xs:string" default="2" />
			778	</xs:restriction>
			779	</xs:simpleContent>
			780	</xs:complexType>
			781	</xs:element>
583	<xs:element name="malignant_neoplasm_metastatic_involvement_sites">	<>	783	<xs:element name="bladder_malignant_neoplasm_metastatic_involvement_sites">
586	<xs:element ref="malignant_neoplasm_metastatic_involvement_site" minOccurs="0" maxOccurs="unbounded" />	<>	786	<xs:element ref="bladder_malignant_neoplasm_metastatic_involvement_site" minOccurs="0" maxOccurs="unbounded" />
591	<xs:element name="malignant_neoplasm_metastatic_involvement_site" nillable="true">	<>	791	<xs:element name="bladder_malignant_neoplasm_metastatic_involvement_site" nillable="true">
		-+	796	<xs:enumeration value="Nodal/soft tissue" />
			797	<xs:enumeration value="Spleen" />
		-+	799	<xs:enumeration value="Lung/pleura" />
602	<xs:enumeration value="Liver" />	+-
603	<xs:enumeration value="Lung" />
604	<xs:enumeration value="Lung/pleura" />
605	<xs:enumeration value="Lymph node only" />
606	<xs:enumeration value="Nodal/soft tissue" />
611	<xs:enumeration value="Spleen" />	<>	809	<xs:enumeration value="Lung" />
			810	<xs:enumeration value="Liver" />
			811	<xs:enumeration value="Lymph node only" />
620	<xs:element name="other_metastatic_involvement_anatomic_site" nillable="true">	<>	820	<xs:element name="bladder_carcinoma_other_metastatic_involvement_anatomic_site_text" nillable="true">
		-+	833	<xs:element name="bladder_carcinoma_clinical_stage" nillable="true">
			834	<xs:annotation><xs:documentation>
			835	The following enumerated values have been DEPRECATED and will be removed in veresion 2.5 of the XSDs.
		-+	837	Stage Unknown
		-+	839	</xs:documentation></xs:annotation>
			840	<xs:complexType mixed="true">
			841	<xs:simpleContent>
			842	<xs:restriction base="utility:clinical_res_attributes">
			843	<xs:enumeration value="" />
			844	<xs:enumeration value="Stage X" />
			845	<xs:enumeration value="Stage Tis" />
			846	<xs:enumeration value="Stage 0" />
			847	<xs:enumeration value="Stage I" />
			848	<xs:enumeration value="Stage IA" />
			849	<xs:enumeration value="Stage IB" />
			850	<xs:enumeration value="Stage II" />
			851	<xs:enumeration value="Stage IIA" />
			852	<xs:enumeration value="Stage IIB" />
			853	<xs:enumeration value="Stage IIC" />
			854	<xs:enumeration value="Stage III" />
			855	<xs:enumeration value="Stage IIIA" />
			856	<xs:enumeration value="Stage IIIB" />
			857	<xs:enumeration value="Stage IIIC" />
			858	<xs:enumeration value="Stage IV" />
			859	<xs:enumeration value="Stage IVA" />
			860	<xs:enumeration value="Stage IVB" />
			861	<xs:enumeration value="Stage IIA Cervix" />
			862	<xs:enumeration value="Stage II Cervix" />
			863	<xs:enumeration value="Stage IB2" />
			864	<xs:enumeration value="Stage IB1" />
			865	<xs:enumeration value="Stage IB Cervix" />
			866	<xs:enumeration value="Stage IA2" />
			867	<xs:enumeration value="Stage IA1" />
			868	<xs:enumeration value="Stage IVC" />
			869	<xs:enumeration value="Stage 0is" />
			870	<xs:enumeration value="Stage 0a" />
			871	<xs:enumeration value="Stage Unknown" />
			872	<xs:attribute name="cde" type="xs:string" default="3203222" />
			873	<xs:attribute name="xsd_ver" type="xs:string" default="2.4.1" />
			874	<xs:attribute name="tier" type="xs:string" default="2" />
			875	</xs:restriction>
			876	</xs:simpleContent>
			877	</xs:complexType>
			878	</xs:element>
647	<xs:annotation>	+-
648	<xs:documentation>
649	The following enumerated values have been DEPRECATED.
651	pT1, pT1a, pT1b, pT1c	+-
652	</xs:documentation>
653	</xs:annotation>
658	<xs:enumeration value="pT0" />	<>	898	<xs:enumeration value="pT4" />
659	<xs:enumeration value="pT2" />		899	<xs:enumeration value="pT3b" />
660	<xs:enumeration value="pT2a" />		900	<xs:enumeration value="pT3a" />
661	<xs:enumeration value="pT2b" />		901	<xs:enumeration value="pT3" />
663	<xs:enumeration value="pT3" />	<>	903	<xs:enumeration value="pT2b" />
664	<xs:enumeration value="pT3a" />		904	<xs:enumeration value="pT2a" />
665	<xs:enumeration value="pT3b" />		905	<xs:enumeration value="pT2" />
666	<xs:enumeration value="pT4" />		906	<xs:enumeration value="pT0" />
		-+	908	<xs:enumeration value="pT1" />
			909	<xs:enumeration value="pT1a" />
			910	<xs:enumeration value="pT1b" />
			911	<xs:enumeration value="pT1c" />
		-+	942	<xs:element name="karnofsky_performance_status_score" nillable="true">
			943	<xs:complexType mixed="true">
			944	<xs:simpleContent>
			945	<xs:restriction base="utility:clinical_res_attributes">
			946	<xs:enumeration value="" />
			947	<xs:enumeration value="100" />
			948	<xs:enumeration value="90" />
			949	<xs:enumeration value="80" />
			950	<xs:enumeration value="70" />
			951	<xs:enumeration value="60" />
			952	<xs:enumeration value="50" />
			953	<xs:enumeration value="40" />
			954	<xs:enumeration value="30" />
			955	<xs:enumeration value="20" />
			956	<xs:enumeration value="10" />
			957	<xs:enumeration value="0" />
			958	<xs:attribute name="cde" type="xs:string" default="2003853" />
			959	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			960	<xs:attribute name="tier" type="xs:string" default="2" />
			961	</xs:restriction>
			962	</xs:simpleContent>
			963	</xs:complexType>
			964	</xs:element>
		-+	966	<xs:element name="performance_status_assessment_eastern_cooperative_oncology_group_scale" nillable="true">
			967	<xs:complexType mixed="true">
			968	<xs:simpleContent>
			969	<xs:restriction base="utility:clinical_res_attributes">
			970	<xs:enumeration value="" />
			971	<xs:enumeration value="0" />
			972	<xs:enumeration value="1" />
			973	<xs:enumeration value="2" />
			974	<xs:enumeration value="3" />
			975	<xs:enumeration value="4" />
			976	<xs:enumeration value="5" />
			977	<xs:attribute name="cde" type="xs:string" default="88" />
			978	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			979	<xs:attribute name="tier" type="xs:string" default="2" />
			980	</xs:restriction>
			981	</xs:simpleContent>
			982	</xs:complexType>
			983	</xs:element>
		-+	985	<xs:element name="primary_therapy_outcome_success_type" nillable="true">
			986	<xs:complexType mixed="true">
			987	<xs:simpleContent>
			988	<xs:restriction base="utility:clinical_res_attributes">
			989	<xs:enumeration value="" />
			990	<xs:enumeration value="Progressive Disease" />
			991	<xs:enumeration value="Stable Disease" />
			992	<xs:enumeration value="Partial Response" />
			993	<xs:enumeration value="Complete Remission/Response" />
			994	<xs:enumeration value="Not Applicable" />
			995	<xs:attribute name="cde" type="xs:string" default="2786727" />
			996	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			997	<xs:attribute name="tier" type="xs:string" default="1" />
			998	</xs:restriction>
			999	</xs:simpleContent>
			1000	</xs:complexType>
			1001	</xs:element>
		-+	1003	<xs:element name="new_neoplasm_event_type" nillable="true">
			1004	<xs:complexType mixed="true">
			1005	<xs:simpleContent>
			1006	<xs:restriction base="utility:clinical_res_attributes">
			1007	<xs:enumeration value="" />
			1008	<xs:enumeration value="Locoregional Disease" />
			1009	<xs:enumeration value="New Primary Tumor" />
			1010	<xs:enumeration value="Metastatic" />
			1011	<xs:enumeration value="Not Applicable" />
			1012	<xs:attribute name="cde" type="xs:string" default="3119721" />
			1013	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			1014	<xs:attribute name="tier" type="xs:string" default="2" />
			1015	</xs:restriction>
			1016	</xs:simpleContent>
			1017	</xs:complexType>
			1018	</xs:element>
		-+	1020	<xs:element name="new_neoplasm_event_occurrence_anatomic_site" nillable="true">
			1021	<xs:complexType mixed="true">
			1022	<xs:simpleContent>
			1023	<xs:restriction base="utility:clinical_res_attributes">
			1024	<xs:enumeration value="" />
			1025	<xs:enumeration value="Renal Pelvis" />
			1026	<xs:enumeration value="Ureter" />
			1027	<xs:enumeration value="Lung" />
			1028	<xs:enumeration value="Urethra" />
			1029	<xs:enumeration value="Lymph Node Only" />
			1030	<xs:enumeration value="Other, specify" />
			1031	<xs:enumeration value="Liver" />
			1032	<xs:enumeration value="Bone" />
			1033	<xs:enumeration value="Bladder" />
			1034	<xs:attribute name="cde" type="xs:string" default="3108271" />
			1035	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			1036	<xs:attribute name="tier" type="xs:string" default="2" />
			1037	</xs:restriction>
			1038	</xs:simpleContent>
			1039	</xs:complexType>
			1040	</xs:element>
		-+	1042	<xs:element name="new_neoplasm_occurrence_anatomic_site_text" nillable="true">
			1043	<xs:complexType>
			1044	<xs:simpleContent>
			1045	<xs:extension base="xs:string">
			1046	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			1047	<xs:attribute name="cde" type="xs:string" default="3128033" />
			1048	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			1049	<xs:attribute name="tier" type="xs:string" default="2" />
			1050	</xs:extension>
			1051	</xs:simpleContent>
			1052	</xs:complexType>
			1053	</xs:element>
		-+	1055	<xs:element name="additional_treatment_completion_success_outcome_type" nillable="true">
			1056	<xs:complexType mixed="true">
			1057	<xs:simpleContent>
			1058	<xs:restriction base="utility:clinical_res_attributes">
			1059	<xs:enumeration value="" />
			1060	<xs:enumeration value="Progressive Disease" />
			1061	<xs:enumeration value="Stable Disease" />
			1062	<xs:enumeration value="Partial Response" />
			1063	<xs:enumeration value="Complete Response" />
			1064	<xs:attribute name="cde" type="xs:string" default="3033278" />
			1065	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			1066	<xs:attribute name="tier" type="xs:string" default="1" />
			1067	</xs:restriction>
			1068	</xs:simpleContent>
			1069	</xs:complexType>
			1070	</xs:element>

   
File: TCGA_BCR.BLCA_Clinical_FollowUp_v2.0.xsd  

1	<?xml version="1.0" encoding="utf-8" ?>	+-
4	<xs:schema elementFormDefault="qualified" version="2.5.0"	+-
5	xmlns:xs="http://www.w3.org/2001/XMLSchema"
6	xmlns:shared="http://tcga.nci/bcr/xml/clinical/shared/2.5"
7	xmlns:blca_shared="http://tcga.nci/bcr/xml/clinical/blca/shared/2.5"
8	xmlns="http://tcga.nci/bcr/xml/clinical/blca/followup/2.5/2.0"
9	targetNamespace="http://tcga.nci/bcr/xml/clinical/blca/followup/2.5/2.0"
10	xmlns:jaxb="http://java.sun.com/xml/ns/jaxb" jaxb:version="1.0" >
12	<xs:annotation>	+-
13	<xs:appinfo>
14	<jaxb:globalBindings generateIsSetMethod="true" />
16	<jaxb:schemaBindings>	+-
17	<jaxb:package name="nci.tcga.bcr.xml.jaxb.clinical.blca" />
18	</jaxb:schemaBindings>
19	</xs:appinfo>
20	</xs:annotation>
22	<xs:annotation>	+-
23	<xs:documentation xml:lang="en">Schema to define the elements of the TCGA Clinical Data Follow-up Form within the BLCA study.</xs:documentation>
24	</xs:annotation>
26	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/shared/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/shared/2.5/TCGA_BCR.Shared_Clinical_Elements.xsd" />	+-
27	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/blca/shared/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/blca/shared/2.5/TCGA_BCR.BLCA_Clinical_Shared_Datatypes.xsd" />
29	<xs:element name="follow_up_v2.0">	+-
30	<xs:complexType>
31	<xs:sequence>
32	<xs:element ref="shared:bcr_patient_barcode" />
33	<xs:element ref="shared:bcr_patient_uuid" />
35	<xs:choice>	+-
36	<xs:sequence>
37	<xs:element ref="shared:day_of_form_completion" />
38	<xs:element ref="shared:month_of_form_completion" />
39	<xs:element ref="shared:year_of_form_completion" />
40	</xs:sequence>
42	<xs:element ref="shared:days_to_form_completion" />	+-
43	</xs:choice>
45	<xs:element ref="shared:followup_case_report_form_submission_reason" />	+-
46	<xs:element ref="shared:radiation_therapy" />
47	<xs:element ref="shared:targeted_molecular_therapy" />
48	<xs:element ref="shared:vital_status" />
50	<xs:choice>	+-
51	<xs:sequence>
52	<xs:element ref="shared:day_of_last_followup" />
53	<xs:element ref="shared:month_of_last_followup" />
54	<xs:element ref="shared:year_of_last_followup" />
55	</xs:sequence>
57	<xs:element ref="shared:days_to_last_followup" />	+-
58	</xs:choice>
60	<xs:choice>	+-
61	<xs:sequence>
62	<xs:element ref="shared:day_of_death" />
63	<xs:element ref="shared:month_of_death" />
64	<xs:element ref="shared:year_of_death" />
65	</xs:sequence>
67	<xs:element ref="shared:days_to_death" />	+-
68	</xs:choice>
70	<xs:element ref="shared:person_neoplasm_cancer_status" />	+-
71	<xs:element ref="blca_shared:primary_therapy_outcome_success" />
72	<xs:element ref="blca_shared:additional_treatment_completion_success_outcome" />
73	<xs:element ref="shared:new_tumor_event_after_initial_treatment" />
75	<xs:choice>	+-
76	<xs:sequence>
77	<xs:element ref="shared:day_of_new_tumor_event_after_initial_treatment" />
78	<xs:element ref="shared:month_of_new_tumor_event_after_initial_treatment" />
79	<xs:element ref="shared:year_of_new_tumor_event_after_initial_treatment" />
80	</xs:sequence>
82	<xs:element ref="shared:days_to_new_tumor_event_after_initial_treatment" />	+-
83	</xs:choice>
85	<xs:element ref="shared:new_neoplasm_event_type" />	+-
86	<xs:element ref="blca_shared:new_neoplasm_event_occurrence_anatomic_site" />
87	<xs:element ref="blca_shared:new_neoplasm_occurrence_anatomic_site_text" />
88	<xs:element ref="shared:additional_surgery_locoregional_procedure" />
90	<xs:choice>	+-
91	<xs:sequence>
92	<xs:element ref="shared:day_of_additional_surgery_metastatic_procedure" />
93	<xs:element ref="shared:month_of_additional_surgery_metastatic_procedure" />
94	<xs:element ref="shared:year_of_additional_surgery_metastatic_procedure" />
95	</xs:sequence>
97	<xs:element ref="shared:days_to_additional_surgery_metastatic_procedure" />	+-
98	</xs:choice>
100	<xs:element ref="shared:additional_radiation_therapy" />	+-
101	<xs:element ref="shared:additional_pharmaceutical_therapy" />
102	</xs:sequence>
104	<xs:attribute name="version" type="xs:string" default="2.0" use="optional"/>	+-
105	</xs:complexType>
106	</xs:element>
107	</xs:schema>

   
File: TCGA_BCR.BLCA_Clinical_Shared_Datatypes.xsd  

1	<?xml version="1.0" encoding="utf-8" ?>	+-
4	<xs:schema elementFormDefault="qualified" version="2.5.0"	+-
5	xmlns:xs="http://www.w3.org/2001/XMLSchema"
6	xmlns:utility="http://tcga.nci/bcr/xml/utility/2.5"
7	xmlns="http://tcga.nci/bcr/xml/clinical/blca/shared/2.5"
8	targetNamespace="http://tcga.nci/bcr/xml/clinical/blca/shared/2.5">
10	<xs:import namespace="http://tcga.nci/bcr/xml/utility/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/utility/2.5/TCGA_BCR.Utility.xsd" />	+-
12	<xs:element name="primary_therapy_outcome_success" nillable="true">	+-
13	<xs:complexType>
14	<xs:simpleContent>
15	<xs:restriction base="utility:clinical_res_attributes">
16	<xs:enumeration value="" />
17	<xs:enumeration value="Complete Remission/Response" />
18	<xs:enumeration value="Not Applicable" />
19	<xs:enumeration value="Partial Remission/Response" />
20	<xs:enumeration value="Persistent Disease" />
21	<xs:enumeration value="Progressive Disease" />
22	<xs:enumeration value="Stable Disease" />
23	<xs:enumeration value="Unknown" />
24	<xs:attribute name="cde" type="xs:string" default="2786727" />
25	<xs:attribute name="xsd_ver" type="xs:string" default="2.5" />
26	<xs:attribute name="tier" type="xs:string" default="2" />
27	</xs:restriction>
28	</xs:simpleContent>
29	</xs:complexType>
30	</xs:element>
32	<xs:element name="additional_treatment_completion_success_outcome" nillable="true">	+-
33	<xs:complexType mixed="true">
34	<xs:simpleContent>
35	<xs:restriction base="utility:clinical_res_attributes">
36	<xs:enumeration value="" />
37	<xs:enumeration value="Complete Response" />
38	<xs:enumeration value="Not Applicable" />
39	<xs:enumeration value="Partial Response" />
40	<xs:enumeration value="Persistent Disease" />
41	<xs:enumeration value="Progressive Disease" />
42	<xs:enumeration value="Stable Disease" />
43	<xs:enumeration value="Unknown" />
44	<xs:attribute name="cde" type="xs:string" default="3033278" />
45	<xs:attribute name="xsd_ver" type="xs:string" default="2.5" />
46	<xs:attribute name="tier" type="xs:string" default="1" />
47	</xs:restriction>
48	</xs:simpleContent>
49	</xs:complexType>
50	</xs:element>
52	<xs:element name="new_neoplasm_event_occurrence_anatomic_site" nillable="true">	+-
53	<xs:complexType mixed="true">
54	<xs:simpleContent>
55	<xs:restriction base="utility:clinical_res_attributes">
56	<xs:enumeration value="" />
57	<xs:enumeration value="Anus" />
58	<xs:enumeration value="Bladder" />
59	<xs:enumeration value="Bone" />
60	<xs:enumeration value="Brain" />
61	<xs:enumeration value="Cervical Lymph Node" />
62	<xs:enumeration value="Cervix" />
63	<xs:enumeration value="Distant Metastasis " />
64	<xs:enumeration value="Head &amp; Neck" />
65	<xs:enumeration value="Hypopharynx" />
66	<xs:enumeration value="Larynx" />
67	<xs:enumeration value="Liver" />
68	<xs:enumeration value="Lung" />
69	<xs:enumeration value="Lymph Node Only" />
70	<xs:enumeration value="Non-regional / Distant Lymph Nodes" />
71	<xs:enumeration value="Not Applicable" />
72	<xs:enumeration value="Oral Cavity" />
73	<xs:enumeration value="Oropharynx" />
74	<xs:enumeration value="Other, specify" />
75	<xs:enumeration value="Peritoneal Surfaces" />
76	<xs:enumeration value="Renal Pelvis" />
77	<xs:enumeration value="Ureter" />
78	<xs:enumeration value="Urethra" />
79	<xs:enumeration value="Vulva" />
80	<xs:attribute name="cde" type="xs:string" default="3108271" />
81	<xs:attribute name="xsd_ver" type="xs:string" default="2.5" />
82	<xs:attribute name="tier" type="xs:string" default="2" />
83	</xs:restriction>
84	</xs:simpleContent>
85	</xs:complexType>
86	</xs:element>
88	<xs:element name="new_neoplasm_occurrence_anatomic_site_text" nillable="true">	+-
89	<xs:complexType>
90	<xs:simpleContent>
91	<xs:extension base="xs:string">
92	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
93	<xs:attribute name="cde" type="xs:string" default="3128033" />
94	<xs:attribute name="xsd_ver" type="xs:string" default="2.5" />
95	<xs:attribute name="tier" type="xs:string" default="2" />
96	</xs:extension>
97	</xs:simpleContent>
98	</xs:complexType>
99	</xs:element>
100	</xs:schema>

   
File: TCGA_BCR.BRCA_Clinical.xsd  

4	<xs:schema elementFormDefault="qualified" version="2.5.0"	<>	4	<xs:schema elementFormDefault="qualified" version="2.4.4"
6	xmlns:utility="http://tcga.nci/bcr/xml/utility/2.5"	<>	6	xmlns:utility="http://tcga.nci/bcr/xml/utility/2.4"
7	xmlns:admin="http://tcga.nci/bcr/xml/administration/2.5"		7	xmlns:admin="http://tcga.nci/bcr/xml/administration/2.4"
8	xmlns:shared="http://tcga.nci/bcr/xml/clinical/shared/2.5"		8	xmlns:shared="http://tcga.nci/bcr/xml/clinical/shared/2.4"
9	xmlns:brca_shared="http://tcga.nci/bcr/xml/clinical/brca/shared/2.5"
10	xmlns:rad="http://tcga.nci/bcr/xml/clinical/radiation/2.5"		9	xmlns:rad="http://tcga.nci/bcr/xml/clinical/radiation/2.4"
11	xmlns:rx="http://tcga.nci/bcr/xml/clinical/pharmaceutical/2.5"		10	xmlns:rx="http://tcga.nci/bcr/xml/clinical/pharmaceutical/2.4"
12	xmlns:cqcf="http://tcga.nci/bcr/xml/clinical/cqcf/2.5"
13	xmlns:follow_up_v1.5="http://tcga.nci/bcr/xml/clinical/brca/followup/2.5/1.5"
14	xmlns:follow_up_v2.1="http://tcga.nci/bcr/xml/clinical/brca/followup/2.5/2.1"
15	xmlns="http://tcga.nci/bcr/xml/clinical/brca/2.5"		11	xmlns="http://tcga.nci/bcr/xml/clinical/brca/2.4"
16	targetNamespace="http://tcga.nci/bcr/xml/clinical/brca/2.5"		12	targetNamespace="http://tcga.nci/bcr/xml/clinical/brca/2.4"
32	<xs:import namespace="http://tcga.nci/bcr/xml/utility/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/utility/2.5/TCGA_BCR.Utility.xsd" />	<>	28	<xs:import namespace="http://tcga.nci/bcr/xml/utility/2.4" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/utility/2.4/TCGA_BCR.Utility.xsd" />
33	<xs:import namespace="http://tcga.nci/bcr/xml/administration/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/administration/2.5/TCGA_BCR.Administration.xsd" />		29	<xs:import namespace="http://tcga.nci/bcr/xml/administration/2.4" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/administration/2.4/TCGA_BCR.Administration.xsd" />
34	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/shared/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/shared/2.5/TCGA_BCR.Shared_Clinical_Elements.xsd" />		30	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/shared/2.4" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/shared/2.4/TCGA_BCR.Shared_Clinical_Elements.xsd" />
35	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/radiation/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/radiation/2.5/TCGA_BCR.Radiation.xsd" />		31	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/radiation/2.4" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/radiation/2.4/TCGA_BCR.Radiation.xsd" />
36	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/pharmaceutical/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/pharmaceutical/2.5/TCGA_BCR.Pharmaceutical.xsd" />		32	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/pharmaceutical/2.4" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/pharmaceutical/2.4/TCGA_BCR.Pharmaceutical.xsd" />
37	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/cqcf/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/cqcf/2.5/TCGA_BCR.CQCF.xsd" />
38	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/brca/shared/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/brca/shared/2.5/TCGA_BCR.BRCA_Clinical_Shared_Datatypes.xsd" />
39	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/brca/followup/2.5/1.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/brca/followup/2.5/TCGA_BCR.BRCA_Clinical_FollowUp_v1.5.xsd" />
40	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/brca/followup/2.5/2.1" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/brca/followup/2.5/TCGA_BCR.BRCA_Clinical_FollowUp_v2.1.xsd" />
49	<xs:attribute name="schemaVersion" type="xs:decimal" use="required" fixed="2.5"/>	<>	41	<xs:attribute name="schemaVersion" type="xs:decimal" use="required" fixed="2.4"/>
60	<xs:element ref="shared:vital_status">	<>	51	<xs:element ref="shared:vital_status" />
61	<xs:annotation>
62	<xs:documentation xml:lang="en">The vital_status question is asked in both the initial enrollment form and the follow-up form(s).</xs:documentation>
63	</xs:annotation>
64	</xs:element>
76	<xs:annotation>	+-
77	<xs:documentation xml:lang="en">
78	The date_of_last_known_alive question is asked in both the initial enrollment form and the follow-up form(s).
80	DEPRECATED:	+-
81	This question is no longer asked on the TCGA Clinical Data initial enrollment form or follow-up Forms (starting with v2.0)
82	within the BRCA study.
83	</xs:documentation>
84	</xs:annotation>
94	<xs:annotation>	+-
95	<xs:documentation xml:lang="en">The date_of_death question is asked in both the initial enrollment form and the follow-up form(s).</xs:documentation>
96	</xs:annotation>
106	<xs:annotation>	+-
107	<xs:documentation xml:lang="en">The date_of_last_followup question is asked in both the initial enrollment form and the follow-up form(s).</xs:documentation>
108	</xs:annotation>
		-+	99	<xs:element ref="shared:radiation_therapy" />
		-+	119	<xs:choice>
			120	<xs:sequence>
			121	<xs:element ref="shared:day_of_new_tumor_event_after_initial_treatment" />
			122	<xs:element ref="shared:month_of_new_tumor_event_after_initial_treatment" />
			123	<xs:element ref="shared:year_of_new_tumor_event_after_initial_treatment" />
			124	</xs:sequence>
		-+	126	<xs:element ref="shared:days_to_new_tumor_event_after_initial_treatment" />
			127	</xs:choice>
		<>	130	<xs:element ref="shared:additional_radiation_therapy" />
141	<xs:element ref="shared:person_neoplasm_cancer_status">		131	<xs:element ref="shared:additional_pharmaceutical_therapy" />
			132	<xs:element ref="shared:additional_surgery_locoregional_procedure" />
142	<xs:annotation>	<>	134	<xs:choice>
143	<xs:documentation xml:lang="en">The person_neoplasm_cancer_status question is asked in both the initial enrollment form and the follow-up form(s).</xs:documentation>		135	<xs:sequence>
			136	<xs:element ref="shared:day_of_additional_surgery_locoregional_procedure" />
			137	<xs:element ref="shared:month_of_additional_surgery_locoregional_procedure" />
			138	<xs:element ref="shared:year_of_additional_surgery_locoregional_procedure" />
			139	</xs:sequence>
		<>	141	<xs:element ref="shared:days_to_additional_surgery_locoregional_procedure" />
144	</xs:annotation>		142	</xs:choice>
		-+	144	<xs:element ref="shared:additional_surgery_metastatic_procedure" />
		<>	146	<xs:choice>
			147	<xs:sequence>
			148	<xs:element ref="shared:day_of_additional_surgery_metastatic_procedure" />
			149	<xs:element ref="shared:month_of_additional_surgery_metastatic_procedure" />
			150	<xs:element ref="shared:year_of_additional_surgery_metastatic_procedure" />
145	</xs:element>		151	</xs:sequence>
		-+	153	<xs:element ref="shared:days_to_additional_surgery_metastatic_procedure" />
			154	</xs:choice>
146	<xs:element ref="shared:primary_lymph_node_presentation_assessment" />	<>	156	<xs:element ref="shared:person_neoplasm_cancer_status" />
147	<xs:element ref="shared:lymph_node_examined_count" />		157	<xs:element ref="lymph_node_examined_count" />
148	<xs:element ref="brca_shared:er_detection_method_text" />		158	<xs:element ref="er_detection_method_text" />
149	<xs:element ref="brca_shared:pgr_detection_method_text" />		159	<xs:element ref="pgr_detection_method_text" />
151	<xs:element ref="shared:ajcc_tumor_stage_code" />	<>	161	<xs:element ref="breast_tumor_pathologic_t_stage" />
152	<xs:element ref="shared:ajcc_neoplasm_disease_lymph_node_stage" />		162	<xs:element ref="breast_tumor_pathologic_n_stage" />
153	<xs:element ref="anatomic_organ_subdivisions" />		163	<xs:element ref="anatomic_site_location_descriptors" />
154	<xs:element ref="brca_shared:her2_neu_chromosone_17_signal_ratio_value" />		164	<xs:element ref="her2_neu_chromosone_17_signal_ratio_value" />
160	<xs:element ref="breast_carcinoma_primary_surgical_procedure_name" />	<>	170	<xs:element ref="breast_carcinoma_first_surgical_procedure_name" />
163	<xs:element ref="shared:tumor_other_histologic_subtype_descriptive_text" />	<>	173	<xs:element ref="tumor_other_histologic_subtype_descriptive_text" />
164	<xs:element ref="menopause_status" />		174	<xs:element ref="person_menopause_status" />
166	<xs:element ref="brca_shared:breast_carcinoma_progesterone_receptor_status" />	<>	175	<xs:element ref="breast_carcinoma_progesterone_receptor_status" />
168	<xs:element ref="breast_carcinoma_immunohistochemistry_er_pos_finding_scale" />	<>
169	<xs:element ref="brca_shared:immunohistochemistry_positive_cell_score" />		177	<xs:element ref="immunohistochemistry_positive_cell_score" />
170	<xs:element ref="brca_shared:her2_immunohistochemistry_level_result" />		178	<xs:element ref="her2_immunohistochemistry_level_result" />
172	<xs:element ref="shared:margin_status" />	<>	180	<xs:element ref="disease_surgical_margin_status" />
173	<xs:element ref="shared:initial_pathologic_diagnosis_method" />		181	<xs:element ref="first_pathologic_diagnosis_biospecimen_acquisition_method_type" />
		<>	183	<xs:element ref="adjuvant_postop_targeted_therapy_admin_indicator" />
175	<xs:element ref="brca_shared:lab_procedure_her2_neu_in_situ_hybrid_outcome_type" />		184	<xs:element ref="lab_procedure_her2_neu_in_situ_hybrid_outcome_type" />
176	<xs:element ref="brca_shared:breast_carcinoma_estrogen_receptor_status" />		185	<xs:element ref="breast_carcinoma_estrogen_receptor_status" />
177	<xs:element ref="brca_shared:lab_proc_her2_neu_immunohistochemistry_receptor_status" />		186	<xs:element ref="lab_proc_her2_neu_immunohistochemistry_receptor_status" />
178	<xs:element ref="shared:number_of_lymphnodes_positive_by_ihc" />		187	<xs:element ref="pos_finding_lymph_node_keratin_immunohistochemistry_staining_method_count" />
179	<xs:element ref="shared:number_of_lymphnodes_positive_by_he" />		188	<xs:element ref="pos_finding_lymph_node_hematoxylin_and_eosin_staining_microscopy_count" />
180	<xs:element ref="brca_shared:pos_finding_progesterone_receptor_other_measurement_scale_text" />		189	<xs:element ref="pos_finding_progesterone_receptor_other_measurement_scale_text" />
181	<xs:element ref="brca_shared:positive_finding_estrogen_receptor_other_measurement_scale_text" />		190	<xs:element ref="positive_finding_estrogen_receptor_other_measurement_scale_text" />
182	<xs:element ref="brca_shared:her2_erbb_pos_finding_cell_percent_category" />		191	<xs:element ref="her2_erbb_pos_finding_cell_percent_category" />
183	<xs:element ref="brca_shared:pos_finding_her2_erbb2_other_measurement_scale_text" />		192	<xs:element ref="pos_finding_her2_erbb2_other_measurement_scale_text" />
184	<xs:element ref="brca_shared:her2_erbb_method_calculation_method_text" />		193	<xs:element ref="her2_erbb_method_calculation_method_text" />
185	<xs:element ref="brca_shared:her2_neu_and_centromere_17_copy_number_analysis_input_total_number_count" />		194	<xs:element ref="her2_neu_and_centromere_17_copy_number_analysis_input_total_number_count" />
186	<xs:element ref="brca_shared:her2_and_centromere_17_positive_finding_other_measurement_scale_text" />		195	<xs:element ref="her2_and_centromere_17_positive_finding_other_measurement_scale_text" />
187	<xs:element ref="brca_shared:her2_erbb_pos_finding_fluorescence_in_situ_hybridization_calculation_method_text" />		196	<xs:element ref="her2_erbb_pos_finding_fluorescence_in_situ_hybridization_calculation_method_text" />
190	<xs:element ref="brca_shared:fluorescence_in_situ_hybridization_diagnostic_procedure_chromosome_17_signal_result_range" />	<>	199	<xs:element ref="fluorescence_in_situ_hybridization_diagnostic_procedure_chromosome_17_signal_result_range" />
192	<xs:element ref="shared:ajcc_cancer_metastasis_stage_code" />	<>	201	<xs:element ref="breast_tumor_clinical_m_stage" />
193	<xs:element ref="brca_shared:er_level_cell_percentage_category" />		202	<xs:element ref="er_level_cell_percentage_category" />
194	<xs:element ref="brca_shared:progesterone_receptor_level_cell_percent_category" />		203	<xs:element ref="progesterone_receptor_level_cell_percent_category" />
195	<xs:element ref="distant_metastasis_present_ind2" />
196	<xs:element ref="brca_shared:metastatic_breast_carcinoma_estrogen_receptor_status" />		204	<xs:element ref="metastatic_breast_carcinoma_estrogen_receptor_status" />
197	<xs:element ref="brca_shared:metastatic_breast_carcinoma_estrogen_receptor_level_cell_percent_category" />		205	<xs:element ref="metastatic_breast_carcinoma_estrogen_receptor_level_cell_percent_category" />
198	<xs:element ref="brca_shared:metastatic_breast_carcinoma_immunohistochemistry_er_pos_cell_score" />		206	<xs:element ref="metastatic_breast_carcinoma_immunohistochemistry_er_pos_cell_score" />
199	<xs:element ref="brca_shared:pos_finding_metastatic_breast_carcinoma_estrogen_receptor_other_measuremenet_scale_text" />		207	<xs:element ref="pos_finding_metastatic_breast_carcinoma_estrogen_receptor_other_measuremenet_scale_text" />
200	<xs:element ref="brca_shared:metastatic_breast_carcinoma_estrogen_receptor_detection_method_text" />		208	<xs:element ref="metastatic_breast_carcinoma_estrogen_receptor_detection_method_text" />
201	<xs:element ref="brca_shared:metastatic_breast_carcinoma_progesterone_receptor_status" />		209	<xs:element ref="metastatic_breast_carcinoma_progesterone_receptor_status" />
202	<xs:element ref="brca_shared:metastatic_breast_carcinoma_lab_proc_her2_neu_immunohistochemistry_receptor_status" />		210	<xs:element ref="metastatic_breast_carcinoma_lab_proc_her2_neu_immunohistochemistry_receptor_status" />
203	<xs:element ref="brca_shared:metastatic_breast_carcinoma_progesterone_receptor_level_cell_percent_category" />		211	<xs:element ref="metastatic_breast_carcinoma_progesterone_receptor_level_cell_percent_category" />
204	<xs:element ref="brca_shared:metastatic_breast_carcinoma_immunohistochemistry_pr_pos_cell_score" />		212	<xs:element ref="metastatic_breast_carcinoma_immunohistochemistry_pr_pos_cell_score" />
205	<xs:element ref="brca_shared:metastatic_breast_carcinoma_pos_finding_progesterone_receptor_other_measure_scale_text" />		213	<xs:element ref="metastatic_breast_carcinoma_pos_finding_progesterone_receptor_other_measure_scale_text" />
206	<xs:element ref="brca_shared:metastatic_breast_carcinoma_progesterone_receptor_detection_method_text" />		214	<xs:element ref="metastatic_breast_carcinoma_progesterone_receptor_detection_method_text" />
207	<xs:element ref="brca_shared:metastatic_breast_carcinoma_her2_erbb_pos_finding_cell_percent_category" />		215	<xs:element ref="metastatic_breast_carcinoma_her2_erbb_pos_finding_cell_percent_category" />
208	<xs:element ref="brca_shared:metastatic_breast_carcinoma_erbb2_immunohistochemistry_level_result" />		216	<xs:element ref="metastatic_breast_carcinoma_erbb2_immunohistochemistry_level_result" />
209	<xs:element ref="brca_shared:metastatic_breast_carcinoma_pos_finding_her2_erbb2_other_measure_scale_text" />		217	<xs:element ref="metastatic_breast_carcinoma_pos_finding_her2_erbb2_other_measure_scale_text" />
210	<xs:element ref="brca_shared:metastatic_breast_carcinoma_her2_erbb_method_calculation_method_text" />		218	<xs:element ref="metastatic_breast_carcinoma_her2_erbb_method_calculation_method_text" />
211	<xs:element ref="brca_shared:metastatic_breast_carcinoma_lab_proc_her2_neu_in_situ_hybridization_outcome_type" />		219	<xs:element ref="metastatic_breast_carcinoma_lab_proc_her2_neu_in_situ_hybridization_outcome_type" />
212	<xs:element ref="brca_shared:metastatic_breast_carcinoma_fluorescence_in_situ_hybridization_diagnostic_proc_centromere_17_signal_result_range" />		220	<xs:element ref="metastatic_breast_carcinoma_fluorescence_in_situ_hybridization_diagnostic_proc_centromere_17_signal_result_range" />
213	<xs:element ref="brca_shared:her2_neu_and_centromere_17_copy_number_metastatic_breast_carcinoma_analysis_input_total_number_count" />		221	<xs:element ref="her2_neu_and_centromere_17_copy_number_metastatic_breast_carcinoma_analysis_input_total_number_count" />
214	<xs:element ref="brca_shared:metastatic_breast_carcinoma_her2_neu_chromosone_17_signal_ratio_value" />		222	<xs:element ref="metastatic_breast_carcinoma_her2_neu_chromosone_17_signal_ratio_value" />
215	<xs:element ref="brca_shared:metastatic_breast_carcinoma_pos_finding_other_scale_measurement_text" />		223	<xs:element ref="metastatic_breast_carcinoma_pos_finding_other_scale_measurement_text" />
216	<xs:element ref="brca_shared:metastatic_breast_carcinoma_her2_erbb_pos_finding_fluorescence_in_situ_hybridization_calculation_method_text" />		224	<xs:element ref="metastatic_breast_carcinoma_her2_erbb_pos_finding_fluorescence_in_situ_hybridization_calculation_method_text" />
217	<xs:element ref="brca_shared:her2_neu_metastatic_breast_carcinoma_copy_analysis_input_total_number" />		225	<xs:element ref="her2_neu_metastatic_breast_carcinoma_copy_analysis_input_total_number" />
218	<xs:element ref="brca_shared:her2_neu_breast_carcinoma_copy_analysis_input_total_number" />		226	<xs:element ref="her2_neu_breast_carcinoma_copy_analysis_input_total_number" />
219	<xs:element ref="breast_carcinoma_immunohistochemistry_progesterone_receptor_pos_finding_scale" />
220	<xs:element ref="brca_shared:breast_carcinoma_immunohistochemistry_pos_cell_score" />		227	<xs:element ref="breast_carcinoma_immunohistochemistry_pos_cell_score" />
221	<xs:element ref="shared:ajcc_neoplasm_disease_stage" />		228	<xs:element ref="breast_tumor_pathologic_grouping_stage" />
224	<xs:annotation>	+-
225	<xs:documentation xml:lang="en">
226	Date the interviewer originally completed the corresponding TCGA Clinical Data Form.
227	If modifications are made after the form is marked complete, this date should not change.
228	</xs:documentation>
229	</xs:annotation>
238	<xs:element ref="follow_ups" />	+-
241	<xs:element ref="clinical_cqcf" />	+-
		<>	246	<xs:element name="lymph_node_examined_count" nillable="true">
			247	<xs:complexType>
246	<xs:element name="follow_ups">		248	<xs:simpleContent>
			249	<xs:extension base="xs:string">
			250	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			251	<xs:attribute name="cde" type="xs:string" default="3" />
			252	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
			253	<xs:attribute name="tier" type="xs:string" default="1" />
247	<xs:annotation>		254	</xs:extension>
248	<xs:documentation xml:lang="en">We are using namespaces and version numbers to distinguish one version of followup from another.</xs:documentation>
249	</xs:annotation>		255	</xs:simpleContent>
			256	</xs:complexType>
			257	</xs:element>
		-+	259	<xs:element name="er_detection_method_text" nillable="true">
251	<xs:sequence>	<>	261	<xs:simpleContent>
252	<xs:element ref="follow_up_v1.5:follow_up_v1.5" minOccurs="0" maxOccurs="unbounded" />		262	<xs:extension base="xs:string">
			263	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			264	<xs:attribute name="cde" type="xs:string" default="69" />
253	<xs:element ref="follow_up_v2.1:follow_up_v2.1" minOccurs="0" maxOccurs="unbounded" />		265	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
			266	<xs:attribute name="tier" type="xs:string" default="1" />
254	</xs:sequence>		267	</xs:extension>
			268	</xs:simpleContent>
258	<xs:element name="clinical_cqcf">	<>	272	<xs:element name="pgr_detection_method_text" nillable="true">
		<>	274	<xs:simpleContent>
			275	<xs:extension base="xs:string">
			276	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			277	<xs:attribute name="cde" type="xs:string" default="785" />
			278	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
			279	<xs:attribute name="tier" type="xs:string" default="1" />
			280	</xs:extension>
			281	</xs:simpleContent>
			282	</xs:complexType>
260	<xs:sequence>		283	</xs:element>
261	<xs:element ref="shared:anatomic_organ_subdivision"/>	<>	285	<xs:element name="breast_tumor_pathologic_t_stage" nillable="true">
			286	<xs:complexType mixed="true">
			287	<xs:simpleContent>
262	<xs:element ref="cqcf:consent_or_death_status"/>		288	<xs:restriction base="utility:clinical_res_attributes">
263			289	<xs:enumeration value="" />
			290	<xs:enumeration value="TX" />
			291	<xs:enumeration value="T0" />
			292	<xs:enumeration value="Tis" />
			293	<xs:enumeration value="Tis (DCIS)" />
			294	<xs:enumeration value="Tis (LCIS)" />
			295	<xs:enumeration value="Tis (Paget's)" />
			296	<xs:enumeration value="T1mi" />
			297	<xs:enumeration value="T1" />
			298	<xs:enumeration value="T1a" />
			299	<xs:enumeration value="T1b" />
			300	<xs:enumeration value="T1c" />
			301	<xs:enumeration value="T2" />
			302	<xs:enumeration value="T2a" />
			303	<xs:enumeration value="T2b" />
			304	<xs:enumeration value="T2c" />
			305	<xs:enumeration value="Ta" />
			306	<xs:enumeration value="T3" />
			307	<xs:enumeration value="T3a" />
			308	<xs:enumeration value="T3b" />
			309	<xs:enumeration value="T3c" />
			310	<xs:enumeration value="T4" />
			311	<xs:enumeration value="T4a" />
			312	<xs:enumeration value="T4b" />
			313	<xs:enumeration value="T4c" />
			314	<xs:enumeration value="T4d" />
			315	<xs:attribute name="cde" type="xs:string" default="3045435" />
			316	<xs:attribute name="xsd_ver" type="xs:string" default="2.4.1" />
			317	<xs:attribute name="tier" type="xs:string" default="1" />
264	<xs:choice>		318	</xs:restriction>
			319	</xs:simpleContent>
265	<xs:choice>		320	</xs:complexType>
266	<xs:sequence>		321	</xs:element>
		<>	323	<xs:element name="breast_tumor_pathologic_n_stage" nillable="true">
			324	<xs:complexType mixed="true">
			325	<xs:simpleContent>
			326	<xs:restriction base="utility:clinical_res_attributes">
267	<xs:element ref="cqcf:day_of_consent"/>		327	<xs:enumeration value="" />
			328	<xs:enumeration value="NX" />
			329	<xs:enumeration value="N0" />
			330	<xs:enumeration value="N0 (i-)" />
			331	<xs:enumeration value="N0 (i+)" />
			332	<xs:enumeration value="N0 (mol-)" />
			333	<xs:enumeration value="N0 (mol+)" />
			334	<xs:enumeration value="N1" />
			335	<xs:enumeration value="N1mi" />
			336	<xs:enumeration value="N1a" />
			337	<xs:enumeration value="N1b" />
			338	<xs:enumeration value="N1bI" />
			339	<xs:enumeration value="N1bII" />
			340	<xs:enumeration value="N1bIII" />
			341	<xs:enumeration value="N1bIV" />
268	<xs:element ref="cqcf:month_of_consent"/>		342	<xs:enumeration value="N1c" />
			343	<xs:enumeration value="N2" />
			344	<xs:enumeration value="N2a" />
			345	<xs:enumeration value="N2b" />
			346	<xs:enumeration value="N3" />
			347	<xs:enumeration value="N3a" />
			348	<xs:enumeration value="N3b" />
269	<xs:element ref="cqcf:year_of_consent"/>		349	<xs:enumeration value="N3c" />
			350	<xs:enumeration value="N4" />
			351	<xs:enumeration value="pN0" /> <!-- Deprecated. Will be removed in 2.5. This permissible value is not in the current CDE -->
			352	<xs:enumeration value="pN1" /> <!-- Deprecated. Will be removed in 2.5. This permissible value is not in the current CDE -->
			353	<xs:enumeration value="pN2" /> <!-- Deprecated. Will be removed in 2.5. This permissible value is not in the current CDE -->
			354	<xs:enumeration value="pN3" /> <!-- Deprecated. Will be removed in 2.5. This permissible value is not in the current CDE -->
			355	<xs:enumeration value="pNX" /> <!-- Deprecated. Will be removed in 2.5. This permissible value is not in the current CDE -->
			356	<xs:enumeration value="pN0(i-)" /> <!-- Deprecated. Will be removed in 2.5. This permissible value is not in the current CDE -->
			357	<xs:enumeration value="pN0(i+)" /> <!-- Deprecated. Will be removed in 2.5. This permissible value is not in the current CDE -->
			358	<xs:enumeration value="pN0(mol-)" /> <!-- Deprecated. Will be removed in 2.5. This permissible value is not in the current CDE -->
			359	<xs:enumeration value="pN0(mol+)" /> <!-- Deprecated. Will be removed in 2.5. This permissible value is not in the current CDE -->
			360	<xs:enumeration value="pN1mi" /> <!-- Deprecated. Will be removed in 2.5. This permissible value is not in the current CDE -->
			361	<xs:enumeration value="pN1a" /> <!-- Deprecated. Will be removed in 2.5. This permissible value is not in the current CDE -->
			362	<xs:enumeration value="pN1b" /> <!-- Deprecated. Will be removed in 2.5. This permissible value is not in the current CDE -->
			363	<xs:enumeration value="pN1c" /> <!-- Deprecated. Will be removed in 2.5. This permissible value is not in the current CDE -->
			364	<xs:enumeration value="pN2a" /> <!-- Deprecated. Will be removed in 2.5. This permissible value is not in the current CDE -->
			365	<xs:enumeration value="pN2b" /> <!-- Deprecated. Will be removed in 2.5. This permissible value is not in the current CDE -->
			366	<xs:enumeration value="pN3a" /> <!-- Deprecated. Will be removed in 2.5. This permissible value is not in the current CDE -->
			367	<xs:enumeration value="pN3b" /> <!-- Deprecated. Will be removed in 2.5. This permissible value is not in the current CDE -->
			368	<xs:enumeration value="pN3c" /> <!-- Deprecated. Will be removed in 2.5. This permissible value is not in the current CDE -->
			369	<xs:attribute name="cde" type="xs:string" default="3203106" />
			370	<xs:attribute name="xsd_ver" type="xs:string" default="2.4.1" />
			371	<xs:attribute name="tier" type="xs:string" default="1" />
			372	</xs:restriction>
			373	</xs:simpleContent>
			374	</xs:complexType>
270	</xs:sequence>		375	</xs:element>
272	<xs:element ref="cqcf:days_to_consent"/>	<>	377	<xs:element name="anatomic_site_location_descriptors">
273	</xs:choice>
275	<xs:choice>	<>	378	<xs:complexType>
277	<xs:element ref="shared:day_of_death"/>	<>	380	<xs:element ref="anatomic_site_location_descriptor" minOccurs="0" maxOccurs="unbounded" />
278	<xs:element ref="shared:month_of_death"/>
279	<xs:element ref="shared:year_of_death"/>
282	<xs:element ref="shared:days_to_death"/>	<>
283	</xs:choice>		382	</xs:complexType>
284	</xs:choice>		383	</xs:element>
		<>	385	<xs:element name="anatomic_site_location_descriptor" nillable="true">
			386	<xs:complexType mixed="true">
			387	<xs:simpleContent>
286	<xs:element ref="cqcf:diagnosis_subtype"/>		388	<xs:restriction base="utility:clinical_res_attributes">
			389	<xs:enumeration value="" />
287	<xs:element ref="shared:prior_diagnosis"/>		390	<xs:enumeration value="Right Upper Inner Quadrant" />
			391	<xs:enumeration value="Right Upper Outer Quadrant" />
			392	<xs:enumeration value="Right Lower Inner Quadrant" />
			393	<xs:enumeration value="Right Lower Outer Quadrant" />
288	<xs:element ref="cqcf:history_of_neoadjuvant_treatment"/>		394	<xs:enumeration value="Left Upper Inner Quadrant" />
289	<xs:element ref="cqcf:normal_tissue_anatomic_site"/>		395	<xs:enumeration value="Left Upper Outer Quadrant" />
290	<xs:element ref="cqcf:normal_tissue_proximity"/>		396	<xs:enumeration value="Left Lower Inner Quadrant" />
			397	<xs:enumeration value="Left Lower Outer Quadrant" />
291	<xs:element ref="cqcf:tumor_focality"/>		398	<xs:enumeration value="Left" />
292	<xs:element ref="cqcf:tumor_type"/>		399	<xs:enumeration value="Right" />
293	<xs:element ref="cqcf:other_diagnosis"/>		400	<xs:attribute name="cde" type="xs:string" default="2008006" />
294	<xs:element ref="cqcf:histological_subtype" minOccurs="0"/>		401	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
295	<xs:element ref="cqcf:other_anatomic_site" minOccurs="0"/>		402	<xs:attribute name="tier" type="xs:string" default="1" />
296	<xs:element ref="cqcf:country"/>		403	</xs:restriction>
297	</xs:sequence>		404	</xs:simpleContent>
301	<xs:element name="anatomic_organ_subdivisions">	<>	408	<xs:element name="her2_neu_chromosone_17_signal_ratio_value" nillable="true">
303	<xs:sequence>	<>	410	<xs:simpleContent>
			411	<xs:extension base="xs:decimal">
			412	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			413	<xs:attribute name="cde" type="xs:string" default="2497552" />
304	<xs:element ref="shared:anatomic_organ_subdivision" minOccurs="0" maxOccurs="unbounded" />		414	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
			415	<xs:attribute name="tier" type="xs:string" default="1" />
305	</xs:sequence>		416	</xs:extension>
			417	</xs:simpleContent>
358	<xs:element name="breast_carcinoma_primary_surgical_procedure_name" nillable="true">	<>	470	<xs:element name="breast_carcinoma_first_surgical_procedure_name" nillable="true">
363	<xs:enumeration value="None" />	<>	475	<xs:enumeration value="Surgery not Performed" />
365	<xs:enumeration value="Mastectomy NOS" />	<>	477	<xs:enumeration value="Simple Mastectomy" />
366	<xs:enumeration value="Modified radical mastectomy" />		478	<xs:enumeration value="Modified Radical Mastectomy" />
368	<xs:attribute name="cde" type="xs:string" default="1218" />	<>	480	<xs:attribute name="cde" type="xs:string" default="2739580" />
381	<xs:attribute name="cde" type="xs:string" default="3020338" />	<>	493	<xs:attribute name="cde" type="xs:string" default="2467630" />
422	<xs:element name="menopause_status" nillable="true">	<>	534	<xs:element name="person_menopause_status" nillable="true">
		-+	551	<xs:element name="breast_carcinoma_progesterone_receptor_status" nillable="true">
			552	<xs:complexType>
			553	<xs:simpleContent>
			554	<xs:extension base="posNegStat">
			555	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			556	<xs:attribute name="cde" type="xs:string" default="2957357" />
			557	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
			558	<xs:attribute name="tier" type="xs:string" default="1" />
			559	</xs:extension>
			560	</xs:simpleContent>
			561	</xs:complexType>
			562	</xs:element>
		-+	577	<xs:element name="immunohistochemistry_positive_cell_score" nillable="true">
			578	<xs:complexType>
			579	<xs:simpleContent>
			580	<xs:extension base="onePlusToFourPlus">
			581	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			582	<xs:attribute name="cde" type="xs:string" default="2230166" />
			583	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
			584	<xs:attribute name="tier" type="xs:string" default="1" />
			585	</xs:extension>
			586	</xs:simpleContent>
			587	</xs:complexType>
			588	</xs:element>
		-+	590	<xs:element name="her2_immunohistochemistry_level_result" nillable="true">
			591	<xs:complexType>
			592	<xs:simpleContent>
			593	<xs:extension base="onePlusToFourPlus">
			594	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			595	<xs:attribute name="cde" type="xs:string" default="2178402" />
			596	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
			597	<xs:attribute name="tier" type="xs:string" default="1" />
			598	</xs:extension>
			599	</xs:simpleContent>
			600	</xs:complexType>
			601	</xs:element>
		-+	603	<xs:element name="breast_cancer_surgery_margin_status" nillable="true">
			604	<xs:complexType>
			605	<xs:simpleContent>
			606	<xs:extension base="posNegClose">
			607	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			608	<xs:attribute name="cde" type="xs:string" default="2241252" />
			609	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
			610	<xs:attribute name="tier" type="xs:string" default="1" />
			611	</xs:extension>
			612	</xs:simpleContent>
			613	</xs:complexType>
			614	</xs:element>
		-+	616	<xs:element name="disease_surgical_margin_status" nillable="true">
			617	<xs:complexType>
			618	<xs:simpleContent>
			619	<xs:extension base="posNegClose">
			620	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			621	<xs:attribute name="cde" type="xs:string" default="3114007" />
			622	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
			623	<xs:attribute name="tier" type="xs:string" default="1" />
			624	</xs:extension>
			625	</xs:simpleContent>
			626	</xs:complexType>
			627	</xs:element>
452	<xs:element name="breast_carcinoma_immunohistochemistry_er_pos_finding_scale" nillable="true">	<>	629	<xs:element name="first_pathologic_diagnosis_biospecimen_acquisition_method_type" nillable="true">
		<>	634	<xs:enumeration value="Other method specify:" />
457	<xs:enumeration value="4 Point Scale" />		635	<xs:enumeration value="Aspirate" />
			636	<xs:enumeration value="Core needle biopsy" />
			637	<xs:enumeration value="Cytology (e.g. Peritoneal or pleural fluid)" />
			638	<xs:enumeration value="Dilation and curettage procedure" />
			639	<xs:enumeration value="Endoscopic Biopsy" />
			640	<xs:enumeration value="Excisional Biopsy" />
			641	<xs:enumeration value="Fine needle aspiration biopsy" />
			642	<xs:enumeration value="Incisional Biopsy" />
458	<xs:enumeration value="3 Point Scale" />		643	<xs:enumeration value="Office Endometrial Biopsy" />
			644	<xs:enumeration value="Tumor resection" />
459	<xs:attribute name="cde" type="xs:string" default="3203081" />		645	<xs:attribute name="cde" type="xs:string" default="2757941" />
460	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />		646	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
		-+	653	<xs:element name="adjuvant_postop_targeted_therapy_admin_indicator" nillable="true">
			654	<xs:complexType>
			655	<xs:simpleContent>
			656	<xs:extension base="utility:yes_or_no">
			657	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			658	<xs:attribute name="cde" type="xs:string" default="2785850" />
			659	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
			660	<xs:attribute name="tier" type="xs:string" default="2" />
			661	</xs:extension>
			662	</xs:simpleContent>
			663	</xs:complexType>
			664	</xs:element>
		-+	666	<xs:element name="lab_procedure_her2_neu_in_situ_hybrid_outcome_type" nillable="true">
			667	<xs:complexType>
			668	<xs:simpleContent>
			669	<xs:extension base="posNegStat">
			670	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			671	<xs:attribute name="cde" type="xs:string" default="2854089" />
			672	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
			673	<xs:attribute name="tier" type="xs:string" default="1" />
			674	</xs:extension>
			675	</xs:simpleContent>
			676	</xs:complexType>
			677	</xs:element>
467	<xs:element name="breast_cancer_surgery_margin_status" nillable="true">	<>	679	<xs:element name="breast_carcinoma_estrogen_receptor_status" nillable="true">
470	<xs:extension base="brca_shared:posNegClose">	<>	682	<xs:extension base="posNegStat">
472	<xs:attribute name="cde" type="xs:string" default="2241252" />	<>	684	<xs:attribute name="cde" type="xs:string" default="2957359" />
			685	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
			686	<xs:attribute name="tier" type="xs:string" default="1" />
			687	</xs:extension>
			688	</xs:simpleContent>
			689	</xs:complexType>
			690	</xs:element>
		-+	692	<xs:element name="lab_proc_her2_neu_immunohistochemistry_receptor_status" nillable="true">
			693	<xs:complexType>
			694	<xs:simpleContent>
			695	<xs:extension base="posNegStat">
			696	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			697	<xs:attribute name="cde" type="xs:string" default="2957563" />
			698	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
			699	<xs:attribute name="tier" type="xs:string" default="1" />
			700	</xs:extension>
			701	</xs:simpleContent>
			702	</xs:complexType>
			703	</xs:element>
		-+	705	<xs:element name="pos_finding_lymph_node_keratin_immunohistochemistry_staining_method_count" nillable="true">
			706	<xs:complexType>
			707	<xs:simpleContent>
			708	<xs:extension base="xs:integer">
			709	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			710	<xs:attribute name="cde" type="xs:string" default="3086383" />
			711	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
			712	<xs:attribute name="tier" type="xs:string" default="1" />
			713	</xs:extension>
			714	</xs:simpleContent>
			715	</xs:complexType>
			716	</xs:element>
		-+	718	<xs:element name="pos_finding_lymph_node_hematoxylin_and_eosin_staining_microscopy_count" nillable="true">
			719	<xs:complexType>
			720	<xs:simpleContent>
			721	<xs:extension base="xs:integer">
			722	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			723	<xs:attribute name="cde" type="xs:string" default="3086388" />
			724	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
			725	<xs:attribute name="tier" type="xs:string" default="1" />
			726	</xs:extension>
			727	</xs:simpleContent>
			728	</xs:complexType>
			729	</xs:element>
		-+	731	<xs:element name="pos_finding_progesterone_receptor_other_measurement_scale_text" nillable="true">
			732	<xs:complexType>
			733	<xs:simpleContent>
			734	<xs:extension base="xs:string">
			735	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			736	<xs:attribute name="cde" type="xs:string" default="3086857" />
			737	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
			738	<xs:attribute name="tier" type="xs:string" default="1" />
			739	</xs:extension>
			740	</xs:simpleContent>
			741	</xs:complexType>
			742	</xs:element>
		-+	744	<xs:element name="positive_finding_estrogen_receptor_other_measurement_scale_text" nillable="true">
			745	<xs:complexType>
			746	<xs:simpleContent>
			747	<xs:extension base="xs:string">
			748	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			749	<xs:attribute name="cde" type="xs:string" default="3086851" />
			750	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
			751	<xs:attribute name="tier" type="xs:string" default="1" />
			752	</xs:extension>
			753	</xs:simpleContent>
			754	</xs:complexType>
			755	</xs:element>
		-+	757	<xs:element name="her2_erbb_pos_finding_cell_percent_category" nillable="true">
			758	<xs:complexType>
			759	<xs:simpleContent>
			760	<xs:extension base="percentByTens">
			761	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			762	<xs:attribute name="cde" type="xs:string" default="3086980" />
			763	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
			764	<xs:attribute name="tier" type="xs:string" default="1" />
			765	</xs:extension>
			766	</xs:simpleContent>
			767	</xs:complexType>
			768	</xs:element>
		-+	770	<xs:element name="pos_finding_her2_erbb2_other_measurement_scale_text" nillable="true">
			771	<xs:complexType>
			772	<xs:simpleContent>
			773	<xs:extension base="xs:string">
			774	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			775	<xs:attribute name="cde" type="xs:string" default="3087479" />
			776	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
			777	<xs:attribute name="tier" type="xs:string" default="1" />
			778	</xs:extension>
			779	</xs:simpleContent>
			780	</xs:complexType>
			781	</xs:element>
		-+	783	<xs:element name="her2_erbb_method_calculation_method_text" nillable="true">
			784	<xs:complexType>
			785	<xs:simpleContent>
			786	<xs:extension base="xs:string">
			787	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			788	<xs:attribute name="cde" type="xs:string" default="3087487" />
			789	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
			790	<xs:attribute name="tier" type="xs:string" default="1" />
			791	</xs:extension>
			792	</xs:simpleContent>
			793	</xs:complexType>
			794	</xs:element>
		-+	796	<xs:element name="her2_neu_and_centromere_17_copy_number_analysis_input_total_number_count" nillable="true">
			797	<xs:complexType>
			798	<xs:simpleContent>
			799	<xs:extension base="xs:integer">
			800	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			801	<xs:attribute name="cde" type="xs:string" default="3087902" />
			802	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
			803	<xs:attribute name="tier" type="xs:string" default="1" />
			804	</xs:extension>
			805	</xs:simpleContent>
			806	</xs:complexType>
			807	</xs:element>
		-+	809	<xs:element name="her2_and_centromere_17_positive_finding_other_measurement_scale_text" nillable="true">
			810	<xs:complexType>
			811	<xs:simpleContent>
			812	<xs:extension base="xs:string">
			813	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			814	<xs:attribute name="cde" type="xs:string" default="3087923" />
			815	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
			816	<xs:attribute name="tier" type="xs:string" default="1" />
			817	</xs:extension>
			818	</xs:simpleContent>
			819	</xs:complexType>
			820	</xs:element>
		-+	822	<xs:element name="her2_erbb_pos_finding_fluorescence_in_situ_hybridization_calculation_method_text" nillable="true">
			823	<xs:complexType>
			824	<xs:simpleContent>
			825	<xs:extension base="xs:string">
			826	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			827	<xs:attribute name="cde" type="xs:string" default="3087929" />
		-+	861	<xs:element name="fluorescence_in_situ_hybridization_diagnostic_procedure_chromosome_17_signal_result_range" nillable="true">
			862	<xs:complexType>
			863	<xs:simpleContent>
			864	<xs:extension base="xs:string">
			865	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			866	<xs:attribute name="cde" type="xs:string" default="3104295" />
			867	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
			868	<xs:attribute name="tier" type="xs:string" default="1" />
			869	</xs:extension>
			870	</xs:simpleContent>
			871	</xs:complexType>
			872	</xs:element>
		-+	874	<xs:element name="tumor_other_histologic_subtype_descriptive_text" nillable="true">
			875	<xs:complexType>
			876	<xs:simpleContent>
			877	<xs:extension base="xs:string">
			878	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			879	<xs:attribute name="cde" type="xs:string" default="3124492" />
			880	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
			881	<xs:attribute name="tier" type="xs:string" default="1" />
			882	</xs:extension>
			883	</xs:simpleContent>
			884	</xs:complexType>
			885	</xs:element>
573	<xs:element name="distant_metastasis_present_ind2" nillable="true">	<>	953	<xs:element name="breast_tumor_clinical_m_stage" nillable="true">
			954	<xs:complexType mixed="true">
			955	<xs:simpleContent>
			956	<xs:restriction base="utility:clinical_res_attributes">
			957	<xs:enumeration value="" />
			958	<xs:enumeration value="MX" />
			959	<xs:enumeration value="M0" />
			960	<xs:enumeration value="M1" />
			961	<xs:enumeration value="M1a" />
			962	<xs:enumeration value="M1b" />
			963	<xs:enumeration value="M1c" />
			964	<xs:enumeration value="cM0 (i+)" />
			965	<xs:attribute name="cde" type="xs:string" default="3045439" />
			966	<xs:attribute name="xsd_ver" type="xs:string" default="2.4.1" />
			967	<xs:attribute name="tier" type="xs:string" default="1" />
			968	</xs:restriction>
			969	</xs:simpleContent>
			970	</xs:complexType>
			971	</xs:element>
		-+	973	<xs:element name="er_level_cell_percentage_category" nillable="true">
		-+	976	<xs:extension base="percentByTens">
			977	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			978	<xs:attribute name="cde" type="xs:string" default="3128341" />
			979	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
			980	<xs:attribute name="tier" type="xs:string" default="1" />
			981	</xs:extension>
			982	</xs:simpleContent>
			983	</xs:complexType>
			984	</xs:element>
		-+	986	<xs:element name="progesterone_receptor_level_cell_percent_category" nillable="true">
			987	<xs:complexType>
			988	<xs:simpleContent>
			989	<xs:extension base="percentByTens">
			990	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			991	<xs:attribute name="cde" type="xs:string" default="3128342" />
			992	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
			993	<xs:attribute name="tier" type="xs:string" default="1" />
			994	</xs:extension>
			995	</xs:simpleContent>
			996	</xs:complexType>
			997	</xs:element>
		-+	999	<xs:element name="metastatic_breast_carcinoma_estrogen_receptor_status" nillable="true">
			1000	<xs:complexType>
			1001	<xs:simpleContent>
			1002	<xs:extension base="posNegStat">
			1003	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			1004	<xs:attribute name="cde" type="xs:string" default="3131865" />
			1005	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
			1006	<xs:attribute name="tier" type="xs:string" default="1" />
			1007	</xs:extension>
			1008	</xs:simpleContent>
			1009	</xs:complexType>
			1010	</xs:element>
		-+	1012	<xs:element name="metastatic_breast_carcinoma_estrogen_receptor_level_cell_percent_category" nillable="true">
			1013	<xs:complexType>
			1014	<xs:simpleContent>
			1015	<xs:extension base="percentByTens">
			1016	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			1017	<xs:attribute name="cde" type="xs:string" default="3131869" />
			1018	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
			1019	<xs:attribute name="tier" type="xs:string" default="1" />
			1020	</xs:extension>
			1021	</xs:simpleContent>
			1022	</xs:complexType>
			1023	</xs:element>
		-+	1025	<xs:element name="metastatic_breast_carcinoma_immunohistochemistry_er_pos_cell_score" nillable="true">
			1026	<xs:complexType>
			1027	<xs:simpleContent>
			1028	<xs:extension base="onePlusToFourPlus">
			1029	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			1030	<xs:attribute name="cde" type="xs:string" default="3131873" />
			1031	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
			1032	<xs:attribute name="tier" type="xs:string" default="1" />
			1033	</xs:extension>
			1034	</xs:simpleContent>
			1035	</xs:complexType>
			1036	</xs:element>
		-+	1038	<xs:element name="pos_finding_metastatic_breast_carcinoma_estrogen_receptor_other_measuremenet_scale_text" nillable="true">
			1039	<xs:complexType>
			1040	<xs:simpleContent>
			1041	<xs:extension base="xs:string">
			1042	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			1043	<xs:attribute name="cde" type="xs:string" default="3131877" />
			1044	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
			1045	<xs:attribute name="tier" type="xs:string" default="1" />
			1046	</xs:extension>
			1047	</xs:simpleContent>
			1048	</xs:complexType>
			1049	</xs:element>
		-+	1051	<xs:element name="metastatic_breast_carcinoma_estrogen_receptor_detection_method_text" nillable="true">
			1052	<xs:complexType>
			1053	<xs:simpleContent>
			1054	<xs:extension base="xs:string">
			1055	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			1056	<xs:attribute name="cde" type="xs:string" default="3131881" />
			1057	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
			1058	<xs:attribute name="tier" type="xs:string" default="1" />
			1059	</xs:extension>
			1060	</xs:simpleContent>
			1061	</xs:complexType>
			1062	</xs:element>
		-+	1064	<xs:element name="metastatic_breast_carcinoma_progesterone_receptor_status" nillable="true">
			1065	<xs:complexType>
			1066	<xs:simpleContent>
			1067	<xs:extension base="posNegStat">
			1068	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			1069	<xs:attribute name="cde" type="xs:string" default="3131884" />
			1070	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
			1071	<xs:attribute name="tier" type="xs:string" default="1" />
			1072	</xs:extension>
			1073	</xs:simpleContent>
			1074	</xs:complexType>
			1075	</xs:element>
		-+	1077	<xs:element name="metastatic_breast_carcinoma_lab_proc_her2_neu_immunohistochemistry_receptor_status" nillable="true">
			1078	<xs:complexType>
			1079	<xs:simpleContent>
			1080	<xs:extension base="posNegStat">
			1081	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			1082	<xs:attribute name="cde" type="xs:string" default="3131997" />
			1083	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
			1084	<xs:attribute name="tier" type="xs:string" default="1" />
			1085	</xs:extension>
			1086	</xs:simpleContent>
			1087	</xs:complexType>
			1088	</xs:element>
		-+	1090	<xs:element name="metastatic_breast_carcinoma_progesterone_receptor_level_cell_percent_category" nillable="true">
			1091	<xs:complexType>
			1092	<xs:simpleContent>
			1093	<xs:extension base="percentByTens">
			1094	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			1095	<xs:attribute name="cde" type="xs:string" default="3131891" />
			1096	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
			1097	<xs:attribute name="tier" type="xs:string" default="1" />
			1098	</xs:extension>
			1099	</xs:simpleContent>
			1100	</xs:complexType>
			1101	</xs:element>
		-+	1103	<xs:element name="metastatic_breast_carcinoma_immunohistochemistry_pr_pos_cell_score" nillable="true">
			1104	<xs:complexType>
			1105	<xs:simpleContent>
			1106	<xs:extension base="onePlusToFourPlus">
			1107	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			1108	<xs:attribute name="cde" type="xs:string" default="3131988" />
			1109	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
			1110	<xs:attribute name="tier" type="xs:string" default="1" />
			1111	</xs:extension>
			1112	</xs:simpleContent>
			1113	</xs:complexType>
			1114	</xs:element>
		-+	1116	<xs:element name="metastatic_breast_carcinoma_pos_finding_progesterone_receptor_other_measure_scale_text" nillable="true">
			1117	<xs:complexType>
			1118	<xs:simpleContent>
			1119	<xs:extension base="xs:string">
			1120	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			1121	<xs:attribute name="cde" type="xs:string" default="3131992" />
			1122	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
			1123	<xs:attribute name="tier" type="xs:string" default="1" />
			1124	</xs:extension>
			1125	</xs:simpleContent>
			1126	</xs:complexType>
			1127	</xs:element>
		-+	1129	<xs:element name="metastatic_breast_carcinoma_progesterone_receptor_detection_method_text" nillable="true">
			1130	<xs:complexType>
			1131	<xs:simpleContent>
			1132	<xs:extension base="xs:string">
			1133	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			1134	<xs:attribute name="cde" type="xs:string" default="3131993" />
			1135	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
			1136	<xs:attribute name="tier" type="xs:string" default="1" />
			1137	</xs:extension>
			1138	</xs:simpleContent>
			1139	</xs:complexType>
			1140	</xs:element>
		-+	1142	<xs:element name="metastatic_breast_carcinoma_her2_erbb_pos_finding_cell_percent_category" nillable="true">
			1143	<xs:complexType>
			1144	<xs:simpleContent>
			1145	<xs:extension base="percentByTens">
			1146	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			1147	<xs:attribute name="cde" type="xs:string" default="3132322" />
			1148	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
			1149	<xs:attribute name="tier" type="xs:string" default="1" />
			1150	</xs:extension>
			1151	</xs:simpleContent>
			1152	</xs:complexType>
			1153	</xs:element>
		-+	1155	<xs:element name="metastatic_breast_carcinoma_erbb2_immunohistochemistry_level_result" nillable="true">
			1156	<xs:complexType>
			1157	<xs:simpleContent>
			1158	<xs:extension base="onePlusToFourPlus">
			1159	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			1160	<xs:attribute name="cde" type="xs:string" default="3132444" />
			1161	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
			1162	<xs:attribute name="tier" type="xs:string" default="1" />
			1163	</xs:extension>
			1164	</xs:simpleContent>
			1165	</xs:complexType>
			1166	</xs:element>
		-+	1168	<xs:element name="metastatic_breast_carcinoma_pos_finding_her2_erbb2_other_measure_scale_text" nillable="true">
			1169	<xs:complexType>
			1170	<xs:simpleContent>
			1171	<xs:extension base="xs:string">
			1172	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			1173	<xs:attribute name="cde" type="xs:string" default="3132448" />
			1174	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
			1175	<xs:attribute name="tier" type="xs:string" default="1" />
			1176	</xs:extension>
			1177	</xs:simpleContent>
			1178	</xs:complexType>
			1179	</xs:element>
		-+	1181	<xs:element name="metastatic_breast_carcinoma_her2_erbb_method_calculation_method_text" nillable="true">
			1182	<xs:complexType>
			1183	<xs:simpleContent>
			1184	<xs:extension base="xs:string">
			1185	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			1186	<xs:attribute name="cde" type="xs:string" default="3132452" />
			1187	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
			1188	<xs:attribute name="tier" type="xs:string" default="1" />
			1189	</xs:extension>
			1190	</xs:simpleContent>
			1191	</xs:complexType>
			1192	</xs:element>
		-+	1194	<xs:element name="metastatic_breast_carcinoma_lab_proc_her2_neu_in_situ_hybridization_outcome_type" nillable="true">
			1195	<xs:complexType>
			1196	<xs:simpleContent>
			1197	<xs:extension base="posNegStat">
			1198	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			1199	<xs:attribute name="cde" type="xs:string" default="3132455" />
			1200	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
			1201	<xs:attribute name="tier" type="xs:string" default="1" />
			1202	</xs:extension>
			1203	</xs:simpleContent>
			1204	</xs:complexType>
			1205	</xs:element>
		-+	1207	<xs:element name="metastatic_breast_carcinoma_fluorescence_in_situ_hybridization_diagnostic_proc_centromere_17_signal_result_range" nillable="true">
			1208	<xs:complexType>
			1209	<xs:simpleContent>
			1210	<xs:extension base="xs:string">
			1211	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			1212	<xs:attribute name="cde" type="xs:string" default="3132887" />
			1213	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
			1214	<xs:attribute name="tier" type="xs:string" default="1" />
			1215	</xs:extension>
			1216	</xs:simpleContent>
			1217	</xs:complexType>
			1218	</xs:element>
		<>	1220	<xs:element name="her2_neu_and_centromere_17_copy_number_metastatic_breast_carcinoma_analysis_input_total_number_count" nillable="true">
			1221	<xs:complexType>
			1222	<xs:simpleContent>
576	<xs:extension base="utility:yes_or_no">		1223	<xs:extension base="xs:integer">
578	<xs:attribute name="cde" type="xs:string" default="2194698" />	<>	1225	<xs:attribute name="cde" type="xs:string" default="3132899" />
579	<xs:attribute name="xsd_ver" type="xs:string" default="2.5" />		1226	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
		-+	1233	<xs:element name="metastatic_breast_carcinoma_her2_neu_chromosone_17_signal_ratio_value" nillable="true">
			1234	<xs:complexType>
			1235	<xs:simpleContent>
			1236	<xs:extension base="xs:decimal">
			1237	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			1238	<xs:attribute name="cde" type="xs:string" default="3132903" />
			1239	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
			1240	<xs:attribute name="tier" type="xs:string" default="1" />
			1241	</xs:extension>
			1242	</xs:simpleContent>
			1243	</xs:complexType>
			1244	</xs:element>
586	<xs:element name="breast_carcinoma_immunohistochemistry_progesterone_receptor_pos_finding_scale" nillable="true">	<>	1246	<xs:element name="metastatic_breast_carcinoma_pos_finding_other_scale_measurement_text" nillable="true">
			1247	<xs:complexType>
			1248	<xs:simpleContent>
			1249	<xs:extension base="xs:string">
			1250	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			1251	<xs:attribute name="cde" type="xs:string" default="3132907" />
			1252	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
			1253	<xs:attribute name="tier" type="xs:string" default="1" />
			1254	</xs:extension>
			1255	</xs:simpleContent>
			1256	</xs:complexType>
			1257	</xs:element>
		-+	1259	<xs:element name="metastatic_breast_carcinoma_her2_erbb_pos_finding_fluorescence_in_situ_hybridization_calculation_method_text" nillable="true">
			1260	<xs:complexType>
			1261	<xs:simpleContent>
			1262	<xs:extension base="xs:string">
			1263	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			1264	<xs:attribute name="cde" type="xs:string" default="3132910" />
			1265	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
			1266	<xs:attribute name="tier" type="xs:string" default="1" />
			1267	</xs:extension>
			1268	</xs:simpleContent>
			1269	</xs:complexType>
			1270	</xs:element>
		-+	1272	<xs:element name="her2_neu_metastatic_breast_carcinoma_copy_analysis_input_total_number" nillable="true">
			1273	<xs:complexType>
			1274	<xs:simpleContent>
			1275	<xs:extension base="xs:string">
			1276	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			1277	<xs:attribute name="cde" type="xs:string" default="3133734" />
			1278	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
			1279	<xs:attribute name="tier" type="xs:string" default="1" />
			1280	</xs:extension>
			1281	</xs:simpleContent>
			1282	</xs:complexType>
			1283	</xs:element>
		-+	1285	<xs:element name="her2_neu_breast_carcinoma_copy_analysis_input_total_number" nillable="true">
			1286	<xs:complexType>
			1287	<xs:simpleContent>
			1288	<xs:extension base="xs:string">
			1289	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			1290	<xs:attribute name="cde" type="xs:string" default="3133738" />
			1291	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
			1292	<xs:attribute name="tier" type="xs:string" default="1" />
			1293	</xs:extension>
			1294	</xs:simpleContent>
			1295	</xs:complexType>
			1296	</xs:element>
		-+	1298	<xs:element name="breast_carcinoma_immunohistochemistry_pos_cell_score" nillable="true">
			1299	<xs:complexType>
			1300	<xs:simpleContent>
			1301	<xs:extension base="onePlusToFourPlus">
			1302	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			1303	<xs:attribute name="cde" type="xs:string" default="3133874" />
			1304	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
			1305	<xs:attribute name="tier" type="xs:string" default="1" />
			1306	</xs:extension>
			1307	</xs:simpleContent>
			1308	</xs:complexType>
			1309	</xs:element>
		-+	1311	<xs:element name="breast_tumor_pathologic_grouping_stage" nillable="true">
591	<xs:enumeration value="4 Point Scale" />	<>	1316	<xs:enumeration value="Stage X" />
592	<xs:enumeration value="3 Point Scale" />		1317	<xs:enumeration value="Stage Tis" />
			1318	<xs:enumeration value="Stage 0" />
			1319	<xs:enumeration value="Stage I" />
			1320	<xs:enumeration value="Stage IA" />
			1321	<xs:enumeration value="Stage IB" />
			1322	<xs:enumeration value="Stage II" />
			1323	<xs:enumeration value="Stage IIA" />
			1324	<xs:enumeration value="Stage IIB" />
			1325	<xs:enumeration value="Stage IIC" />
			1326	<xs:enumeration value="Stage III" />
			1327	<xs:enumeration value="Stage IIIA" />
			1328	<xs:enumeration value="Stage IIIB" />
			1329	<xs:enumeration value="Stage IIIC" />
			1330	<xs:enumeration value="Stage IV" />
			1331	<xs:enumeration value="Stage IVA" />
			1332	<xs:enumeration value="Stage IVB" />
			1333	<xs:enumeration value="Stage IIA Cervix" />
			1334	<xs:enumeration value="Stage II Cervix" />
			1335	<xs:enumeration value="Stage IB2" />
			1336	<xs:enumeration value="Stage IB1" />
			1337	<xs:enumeration value="Stage IB Cervix" />
			1338	<xs:enumeration value="Stage IA2" />
			1339	<xs:enumeration value="Stage IA1" />
			1340	<xs:enumeration value="Stage IVC" />
593	<xs:attribute name="cde" type="xs:string" default="3203083" />		1341	<xs:attribute name="cde" type="xs:string" default="3203222" />
		-+	1349	<xs:simpleType name="percentByTens">
			1350	<xs:restriction base="xs:string">
			1351	<xs:enumeration value="&lt;10%" />
			1352	<xs:enumeration value="10-19%" />
			1353	<xs:enumeration value="20-29%" />
			1354	<xs:enumeration value="30-39%" />
			1355	<xs:enumeration value="40-49%" />
			1356	<xs:enumeration value="50-59%" />
			1357	<xs:enumeration value="60-69%" />
			1358	<xs:enumeration value="70-79%" />
			1359	<xs:enumeration value="80-89%" />
			1360	<xs:enumeration value="90-99%" />
			1361	<xs:enumeration value="90-100%" />
			1362	<xs:enumeration value="" />
			1363	</xs:restriction>
			1364	</xs:simpleType>
		-+	1376	</xs:restriction>
			1377	</xs:simpleType>
		-+	1379	<xs:simpleType name="posNegClose">
			1380	<xs:restriction base="xs:string">
			1381	<xs:enumeration value="" />
			1382	<xs:enumeration value="Positive" />
			1383	<xs:enumeration value="Negative" />
			1384	<xs:enumeration value="Close" />
			1385	</xs:restriction>
			1386	</xs:simpleType>
		-+	1388	<xs:simpleType name="onePlusToFourPlus">
			1389	<xs:restriction base="xs:string">
			1390	<xs:enumeration value="" />
			1391	<xs:enumeration value="0" />
			1392	<xs:enumeration value="1+" />
			1393	<xs:enumeration value="2+" />
			1394	<xs:enumeration value="3+" />
			1395	<xs:enumeration value="4+" />

   
File: TCGA_BCR.BRCA_Clinical_FollowUp_v1.5.xsd  

1	<?xml version="1.0" encoding="utf-8" ?>	+-
3	<xs:schema elementFormDefault="qualified" version="2.5.0"	+-
4	xmlns:xs="http://www.w3.org/2001/XMLSchema"
5	xmlns:shared="http://tcga.nci/bcr/xml/clinical/shared/2.5"
6	xmlns:utility="http://tcga.nci/bcr/xml/utility/2.5"
7	xmlns:admin="http://tcga.nci/bcr/xml/administration/2.5"
8	xmlns:brca_shared="http://tcga.nci/bcr/xml/clinical/brca/shared/2.5"
9	xmlns="http://tcga.nci/bcr/xml/clinical/brca/followup/2.5/1.5"
10	targetNamespace="http://tcga.nci/bcr/xml/clinical/brca/followup/2.5/1.5"
11	xmlns:jaxb="http://java.sun.com/xml/ns/jaxb" jaxb:version="1.0" >
13	<xs:import schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/utility/2.5/TCGA_BCR.Utility.xsd" namespace="http://tcga.nci/bcr/xml/utility/2.5" />	+-
14	<xs:import schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/administration/2.5/TCGA_BCR.Administration.xsd" namespace="http://tcga.nci/bcr/xml/administration/2.5" />
15	<xs:import schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/shared/2.5/TCGA_BCR.Shared_Clinical_Elements.xsd" namespace="http://tcga.nci/bcr/xml/clinical/shared/2.5" />
16	<xs:import schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/brca/shared/2.5/TCGA_BCR.BRCA_Clinical_Shared_Datatypes.xsd" namespace="http://tcga.nci/bcr/xml/clinical/brca/shared/2.5" />
17	<xs:annotation>
18	<xs:appinfo>
19	<jaxb:globalBindings generateIsSetMethod="true" />
20	<jaxb:schemaBindings>
21	<jaxb:package name="nci.tcga.bcr.xml.jaxb.clinical.brca" />
22	</jaxb:schemaBindings>
23	</xs:appinfo>
24	</xs:annotation>
25	<xs:annotation>
26	<xs:documentation xml:lang="en">Schema to define the elements of the TCGA Clinical Data Follow-up Form within the BRCA study.</xs:documentation>
27	</xs:annotation>
28	<xs:element name="follow_up_v1.5">
29	<xs:complexType>
30	<xs:sequence>
31	<xs:element ref="shared:bcr_patient_barcode" />
32	<xs:element ref="shared:bcr_patient_uuid" />
33	<xs:choice>
34	<xs:annotation>
35	<xs:documentation>
36	Data for the DATE_of_last_followup elements are also asked on the
37	TCGA Clinical Data Form during initial enrollment within the BRCA study.
38	</xs:documentation>
39	</xs:annotation>
40	<xs:sequence>
41	<xs:element ref="shared:day_of_last_followup" />
42	<xs:element ref="shared:month_of_last_followup" />
43	<xs:element ref="shared:year_of_last_followup" />
44	</xs:sequence>
45	<xs:element ref="shared:days_to_last_followup" />
46	</xs:choice>
47	<xs:element ref="shared:vital_status">
48	<xs:annotation>
49	<xs:documentation>
50	Data for the vital_status element is also asked on the
51	TCGA Clinical Data Form during initial enrollment within the BRCA study.
52	</xs:documentation>
53	</xs:annotation>
54	</xs:element>
55	<xs:element ref="shared:person_neoplasm_cancer_status">
56	<xs:annotation>
57	<xs:documentation>
58	Data for the DATE_of_person_neoplasm_cancer_status elements are also asked on the
59	TCGA Clinical Data Form during initial enrollment within the BRCA study.
60	</xs:documentation>
61	</xs:annotation>
62	</xs:element>
63	<xs:choice>
64	<xs:annotation>
65	<xs:documentation>
66	Data for the DATE_of_last_known_alive element is also asked on the
67	TCGA Clinical Data Form during initial enrollment within the BRCA study.
69	DEPRECATED:	+-
70	This question is no longer asked on the TCGA Clinical Data Follow-up Form (starting with v2.1)
71	within the BRCA study.
72	</xs:documentation>
73	</xs:annotation>
74	<xs:sequence>
75	<xs:element ref="shared:day_of_last_known_alive" />
76	<xs:element ref="shared:month_of_last_known_alive" />
77	<xs:element ref="shared:year_of_last_known_alive" />
78	</xs:sequence>
79	<xs:element ref="shared:days_to_last_known_alive" />
80	</xs:choice>
81	<xs:choice>
82	<xs:annotation>
83	<xs:documentation>
84	Data for the DATE_of_death elements are also asked on the
85	TCGA Clinical Data Form during initial enrollment within the BRCA study.
86	</xs:documentation>
87	</xs:annotation>
88	<xs:sequence>
89	<xs:element ref="shared:day_of_death" />
90	<xs:element ref="shared:month_of_death" />
91	<xs:element ref="shared:year_of_death" />
92	</xs:sequence>
93	<xs:element ref="shared:days_to_death" />
94	</xs:choice>
95	<xs:element ref="shared:radiation_therapy" />
96	<xs:element ref="shared:targeted_molecular_therapy" />
97	<xs:choice>
98	<xs:sequence>
99	<xs:element ref="shared:day_of_new_tumor_event_after_initial_treatment" />
100	<xs:element ref="shared:month_of_new_tumor_event_after_initial_treatment" />
101	<xs:element ref="shared:year_of_new_tumor_event_after_initial_treatment" />
102	</xs:sequence>
103	<xs:element ref="shared:days_to_new_tumor_event_after_initial_treatment" />
104	</xs:choice>
105	<xs:element ref="shared:additional_surgery_locoregional_procedure" />
106	<xs:choice>
107	<xs:annotation>
108	<xs:documentation>
109	DEPRECATED:
110	This question is no longer asked on the TCGA Clinical Data Follow-up Form (starting with v2.1)
111	within the BRCA study.
112	</xs:documentation>
113	</xs:annotation>
114	<xs:sequence>
115	<xs:element ref="shared:day_of_additional_surgery_locoregional_procedure" />
116	<xs:element ref="shared:month_of_additional_surgery_locoregional_procedure" />
117	<xs:element ref="shared:year_of_additional_surgery_locoregional_procedure" />
118	</xs:sequence>
119	<xs:element ref="shared:days_to_additional_surgery_locoregional_procedure" />
120	</xs:choice>
121	<xs:element ref="brca_shared:breast_carcinoma_estrogen_receptor_status">
122	<xs:annotation>
123	<xs:documentation>
124	Data for the brca_shared:breast_carcinoma_estrogen_receptor_status element is also asked
125	on the TCGA Clinical Data Form during initial enrollment within the BRCA study.
127	DEPRECATED:	+-
128	This question is no longer asked on the TCGA Clinical Data Follow-up Form (starting with v2.1)
129	within the BRCA study.
130	</xs:documentation>
131	</xs:annotation>
132	</xs:element>
133	<xs:element ref="brca_shared:er_level_cell_percentage_category">
134	<xs:annotation>
135	<xs:documentation>
136	Data for the brca_shared:er_level_cell_percentage_category element is also asked
137	on the TCGA Clinical Data Form during initial enrollment within the BRCA study.
139	DEPRECATED:	+-
140	This question is no longer asked on the TCGA Clinical Data Follow-up Form (starting with v2.1)
141	within the BRCA study.
142	</xs:documentation>
143	</xs:annotation>
144	</xs:element>
145	<xs:element ref="brca_shared:immunohistochemistry_positive_cell_score">
146	<xs:annotation>
147	<xs:documentation>
148	Data for the brca_shared:immunohistochemistry_positive_cell_score element is also asked
149	on the TCGA Clinical Data Form during initial enrollment within the BRCA study.
151	DEPRECATED:	+-
152	This question is no longer asked on the TCGA Clinical Data Follow-up Form (starting with v2.1)
153	within the BRCA study.
154	</xs:documentation>
155	</xs:annotation>
156	</xs:element>
157	<xs:element ref="brca_shared:positive_finding_estrogen_receptor_other_measurement_scale_text">
158	<xs:annotation>
159	<xs:documentation>
160	Data for the brca_shared:positive_finding_estrogen_receptor_other_measurement_scale_text element
161	is also asked on the TCGA Clinical Data Form during initial enrollment within the BRCA study.
163	DEPRECATED:	+-
164	This question is no longer asked on the TCGA Clinical Data Follow-up Form (starting with v2.1)
165	within the BRCA study.
166	</xs:documentation>
167	</xs:annotation>
168	</xs:element>
169	<xs:element ref="brca_shared:er_detection_method_text">
170	<xs:annotation>
171	<xs:documentation>
172	Data for the brca_shared:er_detection_method_text element is also asked on the
173	TCGA Clinical Data Form during initial enrollment within the BRCA study.
175	DEPRECATED:	+-
176	This question is no longer asked on the TCGA Clinical Data Follow-up Form (starting with v2.1)
177	within the BRCA study.
178	</xs:documentation>
179	</xs:annotation>
180	</xs:element>
181	<xs:element ref="brca_shared:breast_carcinoma_progesterone_receptor_status">
182	<xs:annotation>
183	<xs:documentation>
184	Data for the brca_shared:breast_carcinoma_progesterone_receptor_status element
185	is also asked on the TCGA Clinical Data Form during initial enrollment within the BRCA study.
187	DEPRECATED:	+-
188	This question is no longer asked on the TCGA Clinical Data Follow-up Form (starting with v2.1)
189	within the BRCA study.
190	</xs:documentation>
191	</xs:annotation>
192	</xs:element>
193	<xs:element ref="brca_shared:progesterone_receptor_level_cell_percent_category">
194	<xs:annotation>
195	<xs:documentation>
196	Data for the brca_shared:progesterone_receptor_level_cell_percent_category element
197	is also asked on the TCGA Clinical Data Form during initial enrollment within the BRCA study.
199	DEPRECATED:	+-
200	This question is no longer asked on the TCGA Clinical Data Follow-up Form (starting with v2.1)
201	within the BRCA study.
202	</xs:documentation>
203	</xs:annotation>
204	</xs:element>
205	<xs:element ref="brca_shared:breast_carcinoma_immunohistochemistry_pos_cell_score">
206	<xs:annotation>
207	<xs:documentation>
208	Data for the brca_shared:breast_carcinoma_immunohistochemistry_pos_cell_score element
209	is also asked on the TCGA Clinical Data Form during initial enrollment within the BRCA study.
211	DEPRECATED:	+-
212	This question is no longer asked on the TCGA Clinical Data Follow-up Form (starting with v2.1)
213	within the BRCA study.
214	</xs:documentation>
215	</xs:annotation>
216	</xs:element>
217	<xs:element ref="brca_shared:pos_finding_progesterone_receptor_other_measurement_scale_text">
218	<xs:annotation>
219	<xs:documentation>
220	Data for the brca_shared:pos_finding_progesterone_receptor_other_measurement_scale_text element
221	is also asked on the TCGA Clinical Data Form during initial enrollment within the BRCA study.
223	DEPRECATED:	+-
224	This question is no longer asked on the TCGA Clinical Data Follow-up Form (starting with v2.1)
225	within the BRCA study.
226	</xs:documentation>
227	</xs:annotation>
228	</xs:element>
229	<xs:element ref="brca_shared:pgr_detection_method_text">
230	<xs:annotation>
231	<xs:documentation>
232	Data for the brca_shared:pgr_detection_method_text element is also asked on the
233	TCGA Clinical Data Form during initial enrollment within the BRCA study.
235	DEPRECATED:	+-
236	This question is no longer asked on the TCGA Clinical Data Follow-up Form (starting with v2.1)
237	within the BRCA study.
238	</xs:documentation>
239	</xs:annotation>
240	</xs:element>
241	<xs:element ref="brca_shared:lab_proc_her2_neu_immunohistochemistry_receptor_status">
242	<xs:annotation>
243	<xs:documentation>
244	Data for the brca_shared:lab_proc_her2_neu_immunohistochemistry_receptor_status element
245	is also asked on the TCGA Clinical Data Form during initial enrollment within the BRCA study.
247	DEPRECATED:	+-
248	This question is no longer asked on the TCGA Clinical Data Follow-up Form (starting with v2.1)
249	within the BRCA study.
250	</xs:documentation>
251	</xs:annotation>
252	</xs:element>
253	<xs:element ref="brca_shared:her2_erbb_pos_finding_cell_percent_category">
254	<xs:annotation>
255	<xs:documentation>
256	Data for the brca_shared:her2_erbb_pos_finding_cell_percent_category element is also asked
257	on the TCGA Clinical Data Form during initial enrollment within the BRCA study.
259	DEPRECATED:	+-
260	This question is no longer asked on the TCGA Clinical Data Follow-up Form (starting with v2.1)
261	within the BRCA study.
262	</xs:documentation>
263	</xs:annotation>
264	</xs:element>
265	<xs:element ref="brca_shared:her2_immunohistochemistry_level_result">
266	<xs:annotation>
267	<xs:documentation>
268	Data for the brca_shared:immunohistochemistry_positive_cell_score element is also asked
269	on the TCGA Clinical Data Form during initial enrollment within the BRCA study.
271	DEPRECATED:	+-
272	This question is no longer asked on the TCGA Clinical Data Follow-up Form (starting with v2.1)
273	within the BRCA study.
274	</xs:documentation>
275	</xs:annotation>
276	</xs:element>
277	<xs:element ref="brca_shared:pos_finding_her2_erbb2_other_measurement_scale_text">
278	<xs:annotation>
279	<xs:documentation>
280	Data for the brca_shared:pos_finding_her2_erbb2_other_measurement_scale_text element
281	is also asked on the TCGA Clinical Data Form during initial enrollment within the BRCA study.
283	DEPRECATED:	+-
284	This question is no longer asked on the TCGA Clinical Data Follow-up Form (starting with v2.1)
285	within the BRCA study.
286	</xs:documentation>
287	</xs:annotation>
288	</xs:element>
289	<xs:element ref="brca_shared:her2_erbb_method_calculation_method_text">
290	<xs:annotation>
291	<xs:documentation>
292	Data for the brca_shared:her2_erbb_method_calculation_method_text element
293	is also asked on the TCGA Clinical Data Form during initial enrollment within the BRCA study.
295	DEPRECATED:	+-
296	This question is no longer asked on the TCGA Clinical Data Follow-up Form (starting with v2.1)
297	within the BRCA study.
298	</xs:documentation>
299	</xs:annotation>
300	</xs:element>
301	<xs:element ref="brca_shared:lab_procedure_her2_neu_in_situ_hybrid_outcome_type">
302	<xs:annotation>
303	<xs:documentation>
304	Data for the brca_shared:lab_procedure_her2_neu_in_situ_hybrid_outcome_type element
305	is also asked on the TCGA Clinical Data Form during initial enrollment within the BRCA study.
307	DEPRECATED:	+-
308	This question is no longer asked on the TCGA Clinical Data Follow-up Form (starting with v2.1)
309	within the BRCA study.
310	</xs:documentation>
311	</xs:annotation>
312	</xs:element>
313	<xs:element ref="brca_shared:her2_neu_breast_carcinoma_copy_analysis_input_total_number">
314	<xs:annotation>
315	<xs:documentation>
316	Data for the brca_shared:her2_neu_breast_carcinoma_copy_analysis_input_total_number element
317	is also asked on the TCGA Clinical Data Form during initial enrollment within the BRCA study.
319	DEPRECATED:	+-
320	This question is no longer asked on the TCGA Clinical Data Follow-up Form (starting with v2.1)
321	within the BRCA study.
322	</xs:documentation>
323	</xs:annotation>
324	</xs:element>
325	<xs:element ref="brca_shared:fluorescence_in_situ_hybridization_diagnostic_procedure_chromosome_17_signal_result_range">
326	<xs:annotation>
327	<xs:documentation>
328	Data for the brca_shared:fluorescence_in_situ_hybridization_diagnostic_procedure_chromosome_17_signal_result_range
329	element is also asked on the TCGA Clinical Data Form during initial enrollment within the BRCA study.
331	DEPRECATED:	+-
332	This question is no longer asked on the TCGA Clinical Data Follow-up Form (starting with v2.1)
333	within the BRCA study.
334	</xs:documentation>
335	</xs:annotation>
336	</xs:element>
337	<xs:element ref="brca_shared:her2_neu_and_centromere_17_copy_number_analysis_input_total_number_count">
338	<xs:annotation>
339	<xs:documentation>
340	Data for the brca_shared:her2_neu_and_centromere_17_copy_number_analysis_input_total_number_count
341	element is also asked on the TCGA Clinical Data Form during initial enrollment within the BRCA study.
343	DEPRECATED:	+-
344	This question is no longer asked on the TCGA Clinical Data Follow-up Form (starting with v2.1)
345	within the BRCA study.
346	</xs:documentation>
347	</xs:annotation>
348	</xs:element>
349	<xs:element ref="brca_shared:her2_neu_chromosone_17_signal_ratio_value">
350	<xs:annotation>
351	<xs:documentation>
352	Data for the brca_shared:her2_neu_chromosone_17_signal_ratio_value element is also asked
353	on the TCGA Clinical Data Form during initial enrollment within the BRCA study.
355	DEPRECATED:	+-
356	This question is no longer asked on the TCGA Clinical Data Follow-up Form (starting with v2.1)
357	within the BRCA study.
358	</xs:documentation>
359	</xs:annotation>
360	</xs:element>
361	<xs:element ref="brca_shared:her2_and_centromere_17_positive_finding_other_measurement_scale_text">
362	<xs:annotation>
363	<xs:documentation>
364	Data for the brca_shared:her2_and_centromere_17_positive_finding_other_measurement_scale_text element
365	is also asked on the TCGA Clinical Data Form during initial enrollment within the BRCA study.
367	DEPRECATED:	+-
368	This question is no longer asked on the TCGA Clinical Data Follow-up Form (starting with v2.1)
369	within the BRCA study.
370	</xs:documentation>
371	</xs:annotation>
372	</xs:element>
373	<xs:element ref="brca_shared:her2_erbb_pos_finding_fluorescence_in_situ_hybridization_calculation_method_text">
374	<xs:annotation>
375	<xs:documentation>
376	Data for the brca_shared:her2_erbb_pos_finding_fluorescence_in_situ_hybridization_calculation_method_text
377	element is also asked on the TCGA Clinical Data Form during initial enrollment within the BRCA study.
379	DEPRECATED:	+-
380	This question is no longer asked on the TCGA Clinical Data Follow-up Form (starting with v2.1)
381	within the BRCA study.
382	</xs:documentation>
383	</xs:annotation>
384	</xs:element>
385	<xs:element ref="shared:additional_surgery_metastatic_procedure">
386	<xs:annotation>
387	<xs:documentation>
388	DEPRECATED:
389	This question is no longer asked on the TCGA Clinical Data Follow-up Form (starting with v2.1)
390	within the BRCA study.
391	</xs:documentation>
392	</xs:annotation>
393	</xs:element>
394	<xs:choice>
395	<xs:sequence>
396	<xs:element ref="shared:day_of_additional_surgery_metastatic_procedure" />
397	<xs:element ref="shared:month_of_additional_surgery_metastatic_procedure" />
398	<xs:element ref="shared:year_of_additional_surgery_metastatic_procedure" />
399	</xs:sequence>
400	<xs:element ref="shared:days_to_additional_surgery_metastatic_procedure" />
401	</xs:choice>
403	<xs:element ref="brca_shared:metastatic_breast_carcinoma_estrogen_receptor_status" />	+-
404	<xs:element ref="brca_shared:metastatic_breast_carcinoma_estrogen_receptor_level_cell_percent_category" />
405	<xs:element ref="brca_shared:metastatic_breast_carcinoma_immunohistochemistry_er_pos_cell_score" />
406	<xs:element ref="brca_shared:pos_finding_metastatic_breast_carcinoma_estrogen_receptor_other_measuremenet_scale_text" />
407	<xs:element ref="brca_shared:metastatic_breast_carcinoma_estrogen_receptor_detection_method_text" />
408	<xs:element ref="brca_shared:metastatic_breast_carcinoma_progesterone_receptor_status" />
409	<xs:element ref="brca_shared:metastatic_breast_carcinoma_progesterone_receptor_level_cell_percent_category" />
410	<xs:element ref="brca_shared:metastatic_breast_carcinoma_immunohistochemistry_pr_pos_cell_score" />
411	<xs:element ref="brca_shared:metastatic_breast_carcinoma_pos_finding_progesterone_receptor_other_measure_scale_text" />
412	<xs:element ref="brca_shared:metastatic_breast_carcinoma_progesterone_receptor_detection_method_text" />
413	<xs:element ref="brca_shared:metastatic_breast_carcinoma_lab_proc_her2_neu_immunohistochemistry_receptor_status" />
414	<xs:element ref="brca_shared:metastatic_breast_carcinoma_her2_erbb_pos_finding_cell_percent_category" />
415	<xs:element ref="brca_shared:metastatic_breast_carcinoma_erbb2_immunohistochemistry_level_result" />
416	<xs:element ref="brca_shared:metastatic_breast_carcinoma_pos_finding_her2_erbb2_other_measure_scale_text" />
417	<xs:element ref="brca_shared:metastatic_breast_carcinoma_her2_erbb_method_calculation_method_text" />
418	<xs:element ref="brca_shared:metastatic_breast_carcinoma_lab_proc_her2_neu_in_situ_hybridization_outcome_type" />
419	<xs:element ref="brca_shared:her2_neu_metastatic_breast_carcinoma_copy_analysis_input_total_number" />
420	<xs:element ref="brca_shared:metastatic_breast_carcinoma_fluorescence_in_situ_hybridization_diagnostic_proc_centromere_17_signal_result_range" />
421	<xs:element ref="brca_shared:her2_neu_and_centromere_17_copy_number_metastatic_breast_carcinoma_analysis_input_total_number_count" />
422	<xs:element ref="brca_shared:metastatic_breast_carcinoma_her2_neu_chromosone_17_signal_ratio_value" />
423	<xs:element ref="brca_shared:metastatic_breast_carcinoma_pos_finding_other_scale_measurement_text" />
424	<xs:element ref="brca_shared:metastatic_breast_carcinoma_her2_erbb_pos_finding_fluorescence_in_situ_hybridization_calculation_method_text" />
426	<xs:element ref="shared:additional_radiation_therapy" />	+-
427	<xs:element ref="shared:additional_pharmaceutical_therapy" />
429	<xs:choice>	+-
430	<xs:annotation>
431	<xs:documentation>
432	Date the interviewer originally completed the corresponding TCGA Clinical Data Form.
433	If modifications are made after the form is marked complete, this date should not change.
434	</xs:documentation>
435	</xs:annotation>
436	<xs:sequence>
437	<xs:element ref="shared:day_of_form_completion" />
438	<xs:element ref="shared:month_of_form_completion" />
439	<xs:element ref="shared:year_of_form_completion" />
440	</xs:sequence>
441	<xs:element ref="shared:days_to_form_completion" />
442	</xs:choice>
443	</xs:sequence>
444	<xs:attribute name="version" type="xs:string" default="1.5" use="optional"/>
445	</xs:complexType>
446	</xs:element>
447	</xs:schema>

   
File: TCGA_BCR.BRCA_Clinical_FollowUp_v2.1.xsd  

1	<?xml version="1.0" encoding="utf-8" ?>	+-
2	<xs:schema elementFormDefault="qualified" version="2.5.0"
3	xmlns:xs="http://www.w3.org/2001/XMLSchema"
4	xmlns:utility="http://tcga.nci/bcr/xml/utility/2.5"
5	xmlns:admin="http://tcga.nci/bcr/xml/administration/2.5"
6	xmlns:shared="http://tcga.nci/bcr/xml/clinical/shared/2.5"
7	xmlns:brca_shared="http://tcga.nci/bcr/xml/clinical/brca/shared/2.5"
8	xmlns="http://tcga.nci/bcr/xml/clinical/brca/followup/2.5/2.1"
9	targetNamespace="http://tcga.nci/bcr/xml/clinical/brca/followup/2.5/2.1"
10	xmlns:jaxb="http://java.sun.com/xml/ns/jaxb" jaxb:version="1.0">
12	<xs:import namespace="http://tcga.nci/bcr/xml/utility/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/utility/2.5/TCGA_BCR.Utility.xsd" />	+-
13	<xs:import namespace="http://tcga.nci/bcr/xml/administration/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/administration/2.5/TCGA_BCR.Administration.xsd" />
14	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/shared/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/shared/2.5/TCGA_BCR.Shared_Clinical_Elements.xsd" />
15	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/brca/shared/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/brca/shared/2.5/TCGA_BCR.BRCA_Clinical_Shared_Datatypes.xsd" />
17	<xs:annotation>	+-
18	<xs:appinfo>
19	<jaxb:globalBindings generateIsSetMethod="true"/>
20	<jaxb:schemaBindings>
21	<jaxb:package name="nci.tcga.bcr.xml.jaxb.clinical.brca"/>
22	</jaxb:schemaBindings>
23	</xs:appinfo>
24	</xs:annotation>
26	<xs:annotation>	+-
27	<xs:documentation xml:lang="en">Schema to define the elements of the TCGA clinical data follow-up form within the BRCA study.</xs:documentation>
28	</xs:annotation>
30	<xs:element name="follow_up_v2.1">	+-
31	<xs:complexType>
32	<xs:sequence>
33	<xs:element ref="shared:bcr_patient_barcode" />
34	<xs:element ref="shared:bcr_patient_uuid" />
35	<xs:element ref="shared:followup_case_report_form_submission_reason" />
36	<xs:element ref="shared:radiation_therapy" />
37	<xs:element ref="shared:targeted_molecular_therapy" />
38	<xs:element ref="shared:vital_status" >
39	<xs:annotation><xs:documentation>
40	Data for the vital_status element is also asked on the
41	TCGA Clinical Data Form during initial enrollment within the BRCA study.
42	</xs:documentation></xs:annotation>
43	</xs:element>
44	<xs:choice>
45	<xs:annotation><xs:documentation>
46	Data for the DATE_of_last_followup elements are also asked on the
47	TCGA Clinical Data Form during initial enrollment within the BRCA study.
48	</xs:documentation></xs:annotation>
49	<xs:sequence>
50	<xs:element ref="shared:day_of_last_followup" />
51	<xs:element ref="shared:month_of_last_followup" />
52	<xs:element ref="shared:year_of_last_followup" />
53	</xs:sequence>
54	<xs:element ref="shared:days_to_last_followup" />
55	</xs:choice>
56	<xs:choice>
57	<xs:annotation><xs:documentation>
58	Data for the DATE_of_death elements are also asked on the
59	TCGA Clinical Data Form during initial enrollment within the BRCA study.
60	</xs:documentation></xs:annotation>
61	<xs:sequence>
62	<xs:element ref="shared:day_of_death" />
63	<xs:element ref="shared:month_of_death" />
64	<xs:element ref="shared:year_of_death" />
65	</xs:sequence>
66	<xs:element ref="shared:days_to_death" />
67	</xs:choice>
68	<xs:element ref="shared:person_neoplasm_cancer_status">
69	<xs:annotation><xs:documentation>
70	Data for the person_neoplasm_cancer_status elements are also asked on the
71	TCGA Clinical Data Form during initial enrollment within the BRCA study.
72	</xs:documentation></xs:annotation>
73	</xs:element>
74	<xs:element ref="shared:new_tumor_event_after_initial_treatment" />
75	<xs:choice>
76	<xs:sequence>
77	<xs:element ref="shared:day_of_new_tumor_event_after_initial_treatment" />
78	<xs:element ref="shared:month_of_new_tumor_event_after_initial_treatment" />
79	<xs:element ref="shared:year_of_new_tumor_event_after_initial_treatment" />
80	</xs:sequence>
82	<xs:element ref="shared:days_to_new_tumor_event_after_initial_treatment" />	+-
83	</xs:choice>
84	<xs:element ref="shared:new_neoplasm_event_type" />
85	<xs:element ref="brca_shared:new_neoplasm_event_occurrence_anatomic_site" />
86	<xs:element ref="brca_shared:new_neoplasm_occurrence_anatomic_site_text" />
87	<xs:element ref="shared:additional_surgery_locoregional_procedure" />
88	<xs:choice>
89	<xs:sequence>
90	<xs:element ref="shared:day_of_additional_surgery_metastatic_procedure" />
91	<xs:element ref="shared:month_of_additional_surgery_metastatic_procedure" />
92	<xs:element ref="shared:year_of_additional_surgery_metastatic_procedure" />
93	</xs:sequence>
95	<xs:element ref="shared:days_to_additional_surgery_metastatic_procedure" />	+-
96	</xs:choice>
97	<xs:element ref="shared:additional_radiation_therapy" />
98	<xs:element ref="shared:additional_pharmaceutical_therapy" />
99	<xs:element ref="brca_shared:metastatic_breast_carcinoma_estrogen_receptor_status" />
100	<xs:element ref="brca_shared:metastatic_breast_carcinoma_estrogen_receptor_level_cell_percent_category" />
101	<xs:element ref="brca_shared:metastatic_breast_carcinoma_immunohistochemistry_er_positive_finding_scale_type">
102	<xs:annotation><xs:documentation>
103	NEW question that was added on the TCGA clinical data follow-up (v2.1) form within the BRCA study.
104	</xs:documentation></xs:annotation>
105	</xs:element>
106	<xs:element ref="brca_shared:pos_finding_metastatic_breast_carcinoma_estrogen_receptor_other_measuremenet_scale_text" />
107	<xs:element ref="brca_shared:metastatic_breast_carcinoma_immunohistochemistry_er_pos_cell_score" />
108	<xs:element ref="brca_shared:metastatic_breast_carcinoma_estrogen_receptor_detection_method_text" />
109	<xs:element ref="brca_shared:metastatic_breast_carcinoma_progesterone_receptor_status" />
110	<xs:element ref="brca_shared:metastatic_breast_carcinoma_progesterone_receptor_level_cell_percent_category" />
111	<xs:element ref="brca_shared:metastatic_breast_carcinoma_immunohistochemistry_progesterone_receptor_positive_finding_scale_type">
112	<xs:annotation><xs:documentation>
113	NEW question that was added on the TCGA Clinical Data Follow-up (starting with v2.1) Form within the BRCA study.
114	</xs:documentation></xs:annotation>
115	</xs:element>
116	<xs:element ref="brca_shared:metastatic_breast_carcinoma_pos_finding_progesterone_receptor_other_measure_scale_text" />
117	<xs:element ref="brca_shared:metastatic_breast_carcinoma_immunohistochemistry_pr_pos_cell_score" />
118	<xs:element ref="brca_shared:metastatic_breast_carcinoma_progesterone_receptor_detection_method_text" />
119	<xs:element ref="brca_shared:metastatic_breast_carcinoma_lab_proc_her2_neu_immunohistochemistry_receptor_status" />
120	<xs:element ref="brca_shared:metastatic_breast_carcinoma_her2_erbb_pos_finding_cell_percent_category" />
121	<xs:element ref="brca_shared:metastatic_breast_carcinoma_erbb2_immunohistochemistry_level_result" />
122	<xs:element ref="brca_shared:metastatic_breast_carcinoma_pos_finding_her2_erbb2_other_measure_scale_text" />
123	<xs:element ref="brca_shared:metastatic_breast_carcinoma_her2_erbb_method_calculation_method_text" />
124	<xs:element ref="brca_shared:metastatic_breast_carcinoma_lab_proc_her2_neu_in_situ_hybridization_outcome_type" />
125	<xs:element ref="brca_shared:her2_neu_metastatic_breast_carcinoma_copy_analysis_input_total_number" />
126	<xs:element ref="brca_shared:metastatic_breast_carcinoma_fluorescence_in_situ_hybridization_diagnostic_proc_centromere_17_signal_result_range" />
127	<xs:element ref="brca_shared:her2_neu_and_centromere_17_copy_number_metastatic_breast_carcinoma_analysis_input_total_number_count" />
128	<xs:element ref="brca_shared:metastatic_breast_carcinoma_her2_neu_chromosone_17_signal_ratio_value" />
129	<xs:element ref="brca_shared:metastatic_breast_carcinoma_pos_finding_other_scale_measurement_text" />
130	<xs:element ref="brca_shared:metastatic_breast_carcinoma_her2_erbb_pos_finding_fluorescence_in_situ_hybridization_calculation_method_text" />
132	<xs:choice>	+-
133	<xs:annotation>
134	<xs:documentation>
135	Date the interviewer originally completed the corresponding TCGA clinical data form.
136	If modifications are made after the form is marked complete, this date should not change.
137	</xs:documentation>
138	</xs:annotation>
139	<xs:sequence>
140	<xs:element ref="shared:day_of_form_completion" />
141	<xs:element ref="shared:month_of_form_completion" />
142	<xs:element ref="shared:year_of_form_completion" />
143	</xs:sequence>
144	<xs:element ref="shared:days_to_form_completion" />
145	</xs:choice>
146	</xs:sequence>
147	<xs:attribute name="version" type="xs:string" default="2.1" use="optional"/>
148	</xs:complexType>
149	</xs:element>
150	</xs:schema>

   
File: TCGA_BCR.BRCA_Clinical_Shared_Datatypes.xsd  

1	<?xml version="1.0" encoding="utf-8" ?>	+-
4	<xs:schema elementFormDefault="qualified" version="2.5.0"	+-
5	xmlns:xs="http://www.w3.org/2001/XMLSchema"
6	xmlns:utility="http://tcga.nci/bcr/xml/utility/2.5"
7	xmlns="http://tcga.nci/bcr/xml/clinical/brca/shared/2.5"
8	targetNamespace="http://tcga.nci/bcr/xml/clinical/brca/shared/2.5">
10	<xs:import namespace="http://tcga.nci/bcr/xml/utility/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/utility/2.5/TCGA_BCR.Utility.xsd" />	+-
12	<xs:element name="new_neoplasm_event_occurrence_anatomic_site" nillable="true">	+-
13	<xs:annotation><xs:documentation>
14	New question that was added TCGA clinical data follow-up (v2.1) form within the BRCA study.
15	This XSD element definition will probably be moved to a more general XSD.
16	</xs:documentation></xs:annotation>
17	<xs:complexType mixed="true">
18	<xs:simpleContent>
19	<xs:restriction base="utility:clinical_res_attributes">
20	<xs:enumeration value="" />
21	<xs:enumeration value="Lung" />
22	<xs:enumeration value="Bone" />
23	<xs:enumeration value="Liver" />
24	<xs:enumeration value="Brain" />
25	<xs:enumeration value="Other, specify" />
26	<xs:attribute name="cde" type="xs:string" default="3108271" />
27	<xs:attribute name="xsd_ver" type="xs:string" default="2.5.0" />
28	<xs:attribute name="tier" type="xs:string" default="1" />
29	</xs:restriction>
30	</xs:simpleContent>
31	</xs:complexType>
32	</xs:element>
34	<xs:element name="new_neoplasm_occurrence_anatomic_site_text" nillable="true">	+-
35	<xs:complexType>
36	<xs:simpleContent>
37	<xs:extension base="xs:string">
38	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
39	<xs:attribute name="cde" type="xs:string" default="3128033" />
40	<xs:attribute name="xsd_ver" type="xs:string" default="2.5.0" />
41	<xs:attribute name="tier" type="xs:string" default="1" />
42	</xs:extension>
43	</xs:simpleContent>
44	</xs:complexType>
45	</xs:element>
47	<xs:element name="er_detection_method_text" nillable="true">	+-
48	<xs:complexType>
49	<xs:simpleContent>
50	<xs:extension base="xs:string">
51	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
52	<xs:attribute name="cde" type="xs:string" default="69" />
53	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
54	<xs:attribute name="tier" type="xs:string" default="1" />
55	</xs:extension>
56	</xs:simpleContent>
57	</xs:complexType>
58	</xs:element>
60	<xs:element name="pgr_detection_method_text" nillable="true">	+-
61	<xs:complexType>
62	<xs:simpleContent>
63	<xs:extension base="xs:string">
64	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
65	<xs:attribute name="cde" type="xs:string" default="785" />
66	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
67	<xs:attribute name="tier" type="xs:string" default="1" />
68	</xs:extension>
69	</xs:simpleContent>
70	</xs:complexType>
71	</xs:element>
73	<xs:element name="her2_neu_chromosone_17_signal_ratio_value" nillable="true">	+-
74	<xs:complexType>
75	<xs:simpleContent>
76	<xs:extension base="utility:number_or_null">
77	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
78	<xs:attribute name="cde" type="xs:string" default="2497552" />
79	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
80	<xs:attribute name="tier" type="xs:string" default="1" />
81	</xs:extension>
82	</xs:simpleContent>
83	</xs:complexType>
84	</xs:element>
86	<xs:element name="breast_carcinoma_progesterone_receptor_status" nillable="true">	+-
87	<xs:complexType>
88	<xs:simpleContent>
89	<xs:extension base="posNegStat">
90	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
91	<xs:attribute name="cde" type="xs:string" default="2957357" />
92	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
93	<xs:attribute name="tier" type="xs:string" default="1" />
94	</xs:extension>
95	</xs:simpleContent>
96	</xs:complexType>
97	</xs:element>
99	<xs:element name="immunohistochemistry_positive_cell_score" nillable="true">	+-
100	<xs:complexType>
101	<xs:simpleContent>
102	<xs:extension base="onePlusToFourPlus">
103	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
104	<xs:attribute name="cde" type="xs:string" default="2230166" />
105	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
106	<xs:attribute name="tier" type="xs:string" default="1" />
107	</xs:extension>
108	</xs:simpleContent>
109	</xs:complexType>
110	</xs:element>
112	<xs:element name="her2_immunohistochemistry_level_result" nillable="true">	+-
113	<xs:annotation><xs:documentation>
114	DEPRECATED: The CDE has changed for this question.
115	See metastatic_breast_carcinoma_immunohistochemistry_er_positive_finding_scale_type
116	</xs:documentation></xs:annotation>
117	<xs:complexType>
118	<xs:simpleContent>
119	<xs:extension base="onePlusToFourPlus">
120	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
121	<xs:attribute name="cde" type="xs:string" default="2178402" />
122	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
123	<xs:attribute name="tier" type="xs:string" default="1" />
124	</xs:extension>
125	</xs:simpleContent>
126	</xs:complexType>
127	</xs:element>
129	<xs:element name="lab_procedure_her2_neu_in_situ_hybrid_outcome_type" nillable="true">	+-
130	<xs:complexType>
131	<xs:simpleContent>
132	<xs:extension base="posNegStat">
133	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
134	<xs:attribute name="cde" type="xs:string" default="2854089" />
135	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
136	<xs:attribute name="tier" type="xs:string" default="1" />
137	</xs:extension>
138	</xs:simpleContent>
139	</xs:complexType>
140	</xs:element>
142	<xs:element name="breast_carcinoma_estrogen_receptor_status" nillable="true">	+-
143	<xs:complexType>
144	<xs:simpleContent>
145	<xs:extension base="posNegStat">
146	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
147	<xs:attribute name="cde" type="xs:string" default="2957359" />
148	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
149	<xs:attribute name="tier" type="xs:string" default="1" />
150	</xs:extension>
151	</xs:simpleContent>
152	</xs:complexType>
153	</xs:element>
155	<xs:element name="lab_proc_her2_neu_immunohistochemistry_receptor_status" nillable="true">	+-
156	<xs:complexType>
157	<xs:simpleContent>
158	<xs:extension base="posNegStat">
159	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
160	<xs:attribute name="cde" type="xs:string" default="2957563" />
161	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
162	<xs:attribute name="tier" type="xs:string" default="1" />
163	</xs:extension>
164	</xs:simpleContent>
165	</xs:complexType>
166	</xs:element>
168	<xs:element name="pos_finding_progesterone_receptor_other_measurement_scale_text" nillable="true">	+-
169	<xs:complexType>
170	<xs:simpleContent>
171	<xs:extension base="xs:string">
172	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
173	<xs:attribute name="cde" type="xs:string" default="3086857" />
174	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
175	<xs:attribute name="tier" type="xs:string" default="1" />
176	</xs:extension>
177	</xs:simpleContent>
178	</xs:complexType>
179	</xs:element>
181	<xs:element name="positive_finding_estrogen_receptor_other_measurement_scale_text" nillable="true">	+-
182	<xs:complexType>
183	<xs:simpleContent>
184	<xs:extension base="xs:string">
185	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
186	<xs:attribute name="cde" type="xs:string" default="3086851" />
187	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
188	<xs:attribute name="tier" type="xs:string" default="1" />
189	</xs:extension>
190	</xs:simpleContent>
191	</xs:complexType>
192	</xs:element>
194	<xs:element name="her2_erbb_pos_finding_cell_percent_category" nillable="true">	+-
195	<xs:complexType>
196	<xs:simpleContent>
197	<xs:extension base="percentByTens">
198	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
199	<xs:attribute name="cde" type="xs:string" default="3086980" />
200	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
201	<xs:attribute name="tier" type="xs:string" default="1" />
202	</xs:extension>
203	</xs:simpleContent>
204	</xs:complexType>
205	</xs:element>
207	<xs:element name="pos_finding_her2_erbb2_other_measurement_scale_text" nillable="true">	+-
208	<xs:complexType>
209	<xs:simpleContent>
210	<xs:extension base="xs:string">
211	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
212	<xs:attribute name="cde" type="xs:string" default="3087479" />
213	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
214	<xs:attribute name="tier" type="xs:string" default="1" />
215	</xs:extension>
216	</xs:simpleContent>
217	</xs:complexType>
218	</xs:element>
220	<xs:element name="her2_erbb_method_calculation_method_text" nillable="true">	+-
221	<xs:complexType>
222	<xs:simpleContent>
223	<xs:extension base="xs:string">
224	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
225	<xs:attribute name="cde" type="xs:string" default="3087487" />
226	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
227	<xs:attribute name="tier" type="xs:string" default="1" />
228	</xs:extension>
229	</xs:simpleContent>
230	</xs:complexType>
231	</xs:element>
233	<xs:element name="her2_neu_and_centromere_17_copy_number_analysis_input_total_number_count" nillable="true">	+-
234	<xs:complexType>
235	<xs:simpleContent>
236	<xs:extension base="utility:integer_or_null">
237	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
238	<xs:attribute name="cde" type="xs:string" default="3087902" />
239	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
240	<xs:attribute name="tier" type="xs:string" default="1" />
241	</xs:extension>
242	</xs:simpleContent>
243	</xs:complexType>
244	</xs:element>
246	<xs:element name="her2_and_centromere_17_positive_finding_other_measurement_scale_text" nillable="true">	+-
247	<xs:complexType>
248	<xs:simpleContent>
249	<xs:extension base="xs:string">
250	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
251	<xs:attribute name="cde" type="xs:string" default="3087923" />
252	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
253	<xs:attribute name="tier" type="xs:string" default="1" />
254	</xs:extension>
255	</xs:simpleContent>
256	</xs:complexType>
257	</xs:element>
259	<xs:element name="her2_erbb_pos_finding_fluorescence_in_situ_hybridization_calculation_method_text" nillable="true">	+-
260	<xs:complexType>
261	<xs:simpleContent>
262	<xs:extension base="xs:string">
263	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
264	<xs:attribute name="cde" type="xs:string" default="3087929" />
265	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
266	<xs:attribute name="tier" type="xs:string" default="1" />
267	</xs:extension>
268	</xs:simpleContent>
269	</xs:complexType>
270	</xs:element>
272	<xs:element name="fluorescence_in_situ_hybridization_diagnostic_procedure_chromosome_17_signal_result_range" nillable="true">	+-
273	<xs:complexType>
274	<xs:simpleContent>
275	<xs:extension base="xs:string">
276	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
277	<xs:attribute name="cde" type="xs:string" default="3104295" />
278	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
279	<xs:attribute name="tier" type="xs:string" default="1" />
280	</xs:extension>
281	</xs:simpleContent>
282	</xs:complexType>
283	</xs:element>
285	<xs:element name="er_level_cell_percentage_category" nillable="true">	+-
286	<xs:complexType>
287	<xs:simpleContent>
288	<xs:extension base="percentByTens">
289	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
290	<xs:attribute name="cde" type="xs:string" default="3128341" />
291	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
292	<xs:attribute name="tier" type="xs:string" default="1" />
293	</xs:extension>
294	</xs:simpleContent>
295	</xs:complexType>
296	</xs:element>
298	<xs:element name="progesterone_receptor_level_cell_percent_category" nillable="true">	+-
299	<xs:complexType>
300	<xs:simpleContent>
301	<xs:extension base="percentByTens">
302	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
303	<xs:attribute name="cde" type="xs:string" default="3128342" />
304	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
305	<xs:attribute name="tier" type="xs:string" default="1" />
306	</xs:extension>
307	</xs:simpleContent>
308	</xs:complexType>
309	</xs:element>
311	<xs:element name="her2_neu_breast_carcinoma_copy_analysis_input_total_number" nillable="true">	+-
312	<xs:complexType>
313	<xs:simpleContent>
314	<xs:extension base="xs:string">
315	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
316	<xs:attribute name="cde" type="xs:string" default="3133738" />
317	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
318	<xs:attribute name="tier" type="xs:string" default="1" />
319	</xs:extension>
320	</xs:simpleContent>
321	</xs:complexType>
322	</xs:element>
324	<xs:element name="breast_carcinoma_immunohistochemistry_pos_cell_score" nillable="true">	+-
325	<xs:complexType>
326	<xs:simpleContent>
327	<xs:extension base="onePlusToFourPlus">
328	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
329	<xs:attribute name="cde" type="xs:string" default="3133874" />
330	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
331	<xs:attribute name="tier" type="xs:string" default="1" />
332	</xs:extension>
333	</xs:simpleContent>
334	</xs:complexType>
335	</xs:element>
337	<xs:element name="metastatic_breast_carcinoma_estrogen_receptor_status" nillable="true">	+-
338	<xs:complexType>
339	<xs:simpleContent>
340	<xs:extension base="posNegStat">
341	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
342	<xs:attribute name="cde" type="xs:string" default="3131865" />
343	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
344	<xs:attribute name="tier" type="xs:string" default="1" />
345	</xs:extension>
346	</xs:simpleContent>
347	</xs:complexType>
348	</xs:element>
350	<xs:element name="metastatic_breast_carcinoma_estrogen_receptor_level_cell_percent_category" nillable="true">	+-
351	<xs:complexType>
352	<xs:simpleContent>
353	<xs:extension base="percentByTens">
354	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
355	<xs:attribute name="cde" type="xs:string" default="3131869" />
356	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
357	<xs:attribute name="tier" type="xs:string" default="1" />
358	</xs:extension>
359	</xs:simpleContent>
360	</xs:complexType>
361	</xs:element>
363	<xs:element name="metastatic_breast_carcinoma_immunohistochemistry_er_positive_finding_scale_type" nillable="true">	+-
364	<xs:annotation><xs:documentation>
365	New question that was added TCGA clinical data follow-up (v2.1) form within the BRCA study
366	</xs:documentation></xs:annotation>
367	<xs:complexType mixed="true">
368	<xs:simpleContent>
369	<xs:restriction base="utility:clinical_res_attributes">
370	<xs:enumeration value="" />
371	<xs:enumeration value="3 Point Scale" />
372	<xs:enumeration value="4 Point Scale" />
373	<xs:enumeration value="Other Reporting Scale" />
374	<xs:attribute name="cde" type="xs:string" default="3203082" />
375	<xs:attribute name="xsd_ver" type="xs:string" default="2.5.0" />
376	<xs:attribute name="tier" type="xs:string" default="1" />
377	</xs:restriction>
378	</xs:simpleContent>
379	</xs:complexType>
380	</xs:element>
382	<xs:element name="metastatic_breast_carcinoma_immunohistochemistry_er_pos_cell_score" nillable="true">	+-
383	<xs:complexType>
384	<xs:simpleContent>
385	<xs:extension base="onePlusToFourPlus">
386	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
387	<xs:attribute name="cde" type="xs:string" default="3131873" />
388	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
389	<xs:attribute name="tier" type="xs:string" default="1" />
390	</xs:extension>
391	</xs:simpleContent>
392	</xs:complexType>
393	</xs:element>
395	<xs:element name="pos_finding_metastatic_breast_carcinoma_estrogen_receptor_other_measuremenet_scale_text" nillable="true">	+-
396	<xs:complexType>
397	<xs:simpleContent>
398	<xs:extension base="xs:string">
399	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
400	<xs:attribute name="cde" type="xs:string" default="3131877" />
401	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
402	<xs:attribute name="tier" type="xs:string" default="1" />
403	</xs:extension>
404	</xs:simpleContent>
405	</xs:complexType>
406	</xs:element>
408	<xs:element name="metastatic_breast_carcinoma_estrogen_receptor_detection_method_text" nillable="true">	+-
409	<xs:complexType>
410	<xs:simpleContent>
411	<xs:extension base="xs:string">
412	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
413	<xs:attribute name="cde" type="xs:string" default="3131881" />
414	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
415	<xs:attribute name="tier" type="xs:string" default="1" />
416	</xs:extension>
417	</xs:simpleContent>
418	</xs:complexType>
419	</xs:element>
421	<xs:element name="metastatic_breast_carcinoma_progesterone_receptor_status" nillable="true">	+-
422	<xs:complexType>
423	<xs:simpleContent>
424	<xs:extension base="posNegStat">
425	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
426	<xs:attribute name="cde" type="xs:string" default="3131884" />
427	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
428	<xs:attribute name="tier" type="xs:string" default="1" />
429	</xs:extension>
430	</xs:simpleContent>
431	</xs:complexType>
432	</xs:element>
434	<xs:element name="metastatic_breast_carcinoma_lab_proc_her2_neu_immunohistochemistry_receptor_status" nillable="true">	+-
435	<xs:complexType>
436	<xs:simpleContent>
437	<xs:extension base="posNegStat">
438	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
439	<xs:attribute name="cde" type="xs:string" default="3131997" />
440	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
441	<xs:attribute name="tier" type="xs:string" default="1" />
442	</xs:extension>
443	</xs:simpleContent>
444	</xs:complexType>
445	</xs:element>
447	<xs:element name="metastatic_breast_carcinoma_progesterone_receptor_level_cell_percent_category" nillable="true">	+-
448	<xs:complexType>
449	<xs:simpleContent>
450	<xs:extension base="percentByTens">
451	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
452	<xs:attribute name="cde" type="xs:string" default="3131891" />
453	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
454	<xs:attribute name="tier" type="xs:string" default="1" />
455	</xs:extension>
456	</xs:simpleContent>
457	</xs:complexType>
458	</xs:element>
460	<xs:element name="metastatic_breast_carcinoma_immunohistochemistry_progesterone_receptor_positive_finding_scale_type" nillable="true">	+-
461	<xs:annotation><xs:documentation>
462	New question that was added TCGA clinical data follow-up (v2.1) form within the BRCA study
463	</xs:documentation></xs:annotation>
464	<xs:complexType mixed="true">
465	<xs:simpleContent>
466	<xs:restriction base="utility:clinical_res_attributes">
467	<xs:enumeration value="" />
468	<xs:enumeration value="3 Point Scale" />
469	<xs:enumeration value="4 Point Scale" />
470	<xs:enumeration value="Other Reporting Scale" />
471	<xs:attribute name="cde" type="xs:string" default="3203085" />
472	<xs:attribute name="xsd_ver" type="xs:string" default="2.5.0" />
473	<xs:attribute name="tier" type="xs:string" default="1" />
474	</xs:restriction>
475	</xs:simpleContent>
476	</xs:complexType>
477	</xs:element>
479	<xs:element name="metastatic_breast_carcinoma_immunohistochemistry_pr_pos_cell_score" nillable="true">	+-
480	<xs:complexType>
481	<xs:simpleContent>
482	<xs:extension base="onePlusToFourPlus">
483	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
484	<xs:attribute name="cde" type="xs:string" default="3131988" />
485	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
486	<xs:attribute name="tier" type="xs:string" default="1" />
487	</xs:extension>
488	</xs:simpleContent>
489	</xs:complexType>
490	</xs:element>
492	<xs:element name="metastatic_breast_carcinoma_pos_finding_progesterone_receptor_other_measure_scale_text" nillable="true">	+-
493	<xs:complexType>
494	<xs:simpleContent>
495	<xs:extension base="xs:string">
496	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
497	<xs:attribute name="cde" type="xs:string" default="3131992" />
498	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
499	<xs:attribute name="tier" type="xs:string" default="1" />
500	</xs:extension>
501	</xs:simpleContent>
502	</xs:complexType>
503	</xs:element>
505	<xs:element name="metastatic_breast_carcinoma_progesterone_receptor_detection_method_text" nillable="true">	+-
506	<xs:complexType>
507	<xs:simpleContent>
508	<xs:extension base="xs:string">
509	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
510	<xs:attribute name="cde" type="xs:string" default="3131993" />
511	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
512	<xs:attribute name="tier" type="xs:string" default="1" />
513	</xs:extension>
514	</xs:simpleContent>
515	</xs:complexType>
516	</xs:element>
518	<xs:element name="metastatic_breast_carcinoma_her2_erbb_pos_finding_cell_percent_category" nillable="true">	+-
519	<xs:complexType>
520	<xs:simpleContent>
521	<xs:extension base="percentByTens">
522	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
523	<xs:attribute name="cde" type="xs:string" default="3132322" />
524	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
525	<xs:attribute name="tier" type="xs:string" default="1" />
526	</xs:extension>
527	</xs:simpleContent>
528	</xs:complexType>
529	</xs:element>
531	<xs:element name="metastatic_breast_carcinoma_erbb2_immunohistochemistry_level_result" nillable="true">	+-
532	<xs:complexType>
533	<xs:simpleContent>
534	<xs:extension base="onePlusToFourPlus">
535	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
536	<xs:attribute name="cde" type="xs:string" default="3132444" />
537	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
538	<xs:attribute name="tier" type="xs:string" default="1" />
539	</xs:extension>
540	</xs:simpleContent>
541	</xs:complexType>
542	</xs:element>
544	<xs:element name="metastatic_breast_carcinoma_pos_finding_her2_erbb2_other_measure_scale_text" nillable="true">	+-
545	<xs:complexType>
546	<xs:simpleContent>
547	<xs:extension base="xs:string">
548	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
549	<xs:attribute name="cde" type="xs:string" default="3132448" />
550	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
551	<xs:attribute name="tier" type="xs:string" default="1" />
552	</xs:extension>
553	</xs:simpleContent>
554	</xs:complexType>
555	</xs:element>
557	<xs:element name="metastatic_breast_carcinoma_her2_erbb_method_calculation_method_text" nillable="true">	+-
558	<xs:complexType>
559	<xs:simpleContent>
560	<xs:extension base="xs:string">
561	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
562	<xs:attribute name="cde" type="xs:string" default="3132452" />
563	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
564	<xs:attribute name="tier" type="xs:string" default="1" />
565	</xs:extension>
566	</xs:simpleContent>
567	</xs:complexType>
568	</xs:element>
570	<xs:element name="metastatic_breast_carcinoma_lab_proc_her2_neu_in_situ_hybridization_outcome_type" nillable="true">	+-
571	<xs:complexType>
572	<xs:simpleContent>
573	<xs:extension base="posNegStat">
574	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
575	<xs:attribute name="cde" type="xs:string" default="3132455" />
576	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
577	<xs:attribute name="tier" type="xs:string" default="1" />
578	</xs:extension>
579	</xs:simpleContent>
580	</xs:complexType>
581	</xs:element>
583	<xs:element name="metastatic_breast_carcinoma_fluorescence_in_situ_hybridization_diagnostic_proc_centromere_17_signal_result_range" nillable="true">	+-
584	<xs:complexType>
585	<xs:simpleContent>
586	<xs:extension base="xs:string">
587	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
588	<xs:attribute name="cde" type="xs:string" default="3132887" />
589	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
590	<xs:attribute name="tier" type="xs:string" default="1" />
591	</xs:extension>
592	</xs:simpleContent>
593	</xs:complexType>
594	</xs:element>
596	<xs:element name="her2_neu_and_centromere_17_copy_number_metastatic_breast_carcinoma_analysis_input_total_number_count" nillable="true">	+-
597	<xs:complexType>
598	<xs:simpleContent>
599	<xs:extension base="utility:integer_or_null">
600	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
601	<xs:attribute name="cde" type="xs:string" default="3132899" />
602	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
603	<xs:attribute name="tier" type="xs:string" default="1" />
604	</xs:extension>
605	</xs:simpleContent>
606	</xs:complexType>
607	</xs:element>
609	<xs:element name="metastatic_breast_carcinoma_her2_neu_chromosone_17_signal_ratio_value" nillable="true">	+-
610	<xs:complexType>
611	<xs:simpleContent>
612	<xs:extension base="utility:number_or_null">
613	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
614	<xs:attribute name="cde" type="xs:string" default="3132903" />
615	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
616	<xs:attribute name="tier" type="xs:string" default="1" />
617	</xs:extension>
618	</xs:simpleContent>
619	</xs:complexType>
620	</xs:element>
622	<xs:element name="metastatic_breast_carcinoma_pos_finding_other_scale_measurement_text" nillable="true">	+-
623	<xs:complexType>
624	<xs:simpleContent>
625	<xs:extension base="xs:string">
626	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
627	<xs:attribute name="cde" type="xs:string" default="3132907" />
628	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
629	<xs:attribute name="tier" type="xs:string" default="1" />
630	</xs:extension>
631	</xs:simpleContent>
632	</xs:complexType>
633	</xs:element>
635	<xs:element name="metastatic_breast_carcinoma_her2_erbb_pos_finding_fluorescence_in_situ_hybridization_calculation_method_text" nillable="true">	+-
636	<xs:complexType>
637	<xs:simpleContent>
638	<xs:extension base="xs:string">
639	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
640	<xs:attribute name="cde" type="xs:string" default="3132910" />
641	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
642	<xs:attribute name="tier" type="xs:string" default="1" />
643	</xs:extension>
644	</xs:simpleContent>
645	</xs:complexType>
646	</xs:element>
648	<xs:element name="her2_neu_metastatic_breast_carcinoma_copy_analysis_input_total_number" nillable="true">	+-
649	<xs:complexType>
650	<xs:simpleContent>
651	<xs:extension base="xs:string">
652	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
653	<xs:attribute name="cde" type="xs:string" default="3133734" />
654	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
655	<xs:attribute name="tier" type="xs:string" default="1" />
656	</xs:extension>
657	</xs:simpleContent>
658	</xs:complexType>
659	</xs:element>
661	<xs:simpleType name="percentByTens">	+-
662	<xs:restriction base="xs:string">
663	<xs:enumeration value="&lt;10%" />
664	<xs:enumeration value="10-19%" />
665	<xs:enumeration value="20-29%" />
666	<xs:enumeration value="30-39%" />
667	<xs:enumeration value="40-49%" />
668	<xs:enumeration value="50-59%" />
669	<xs:enumeration value="60-69%" />
670	<xs:enumeration value="70-79%" />
671	<xs:enumeration value="80-89%" />
672	<xs:enumeration value="90-99%" />
673	<xs:enumeration value="" />
674	</xs:restriction>
675	</xs:simpleType>
677	<xs:simpleType name="posNegStat">	+-
678	<xs:restriction base="xs:string">
679	<xs:enumeration value="" />
680	<xs:enumeration value="Positive" />
681	<xs:enumeration value="Negative" />
682	<xs:enumeration value="Unknown" />
683	<xs:enumeration value="Equivocal" />
684	<xs:enumeration value="Indeterminate" />
685	<xs:enumeration value="Performed but Not Available" />
686	<xs:enumeration value="Not Performed" />
687	</xs:restriction>
688	</xs:simpleType>
690	<xs:simpleType name="posNegClose">	+-
691	<xs:restriction base="xs:string">
692	<xs:enumeration value="" />
693	<xs:enumeration value="Positive" />
694	<xs:enumeration value="Negative" />
695	<xs:enumeration value="Close" />
696	</xs:restriction>
697	</xs:simpleType>
699	<xs:simpleType name="onePlusToFourPlus">	+-
700	<xs:restriction base="xs:string">
701	<xs:enumeration value="" />
702	<xs:enumeration value="0" />
703	<xs:enumeration value="1+" />
704	<xs:enumeration value="2+" />
705	<xs:enumeration value="3+" />
706	<xs:enumeration value="4+" />
707	</xs:restriction>
708	</xs:simpleType>
710	</xs:schema>	+-

   
File: TCGA_BCR.CESC_Clinical.xsd  

4	<xs:schema elementFormDefault="qualified" version="2.5.0"	<>	4	<xs:schema elementFormDefault="qualified" version="2.4.4"
6	xmlns:utility="http://tcga.nci/bcr/xml/utility/2.5"	<>	6	xmlns:utility="http://tcga.nci/bcr/xml/utility/2.4"
7	xmlns:admin="http://tcga.nci/bcr/xml/administration/2.5"		7	xmlns:admin="http://tcga.nci/bcr/xml/administration/2.4"
8	xmlns:shared="http://tcga.nci/bcr/xml/clinical/shared/2.5"		8	xmlns:shared="http://tcga.nci/bcr/xml/clinical/shared/2.4"
9	xmlns:rad="http://tcga.nci/bcr/xml/clinical/radiation/2.5"		9	xmlns:rad="http://tcga.nci/bcr/xml/clinical/radiation/2.4"
10	xmlns:rx="http://tcga.nci/bcr/xml/clinical/pharmaceutical/2.5"		10	xmlns:rx="http://tcga.nci/bcr/xml/clinical/pharmaceutical/2.4"
11	xmlns:cqcf="http://tcga.nci/bcr/xml/clinical/cqcf/2.5"
12	xmlns:cesc_shared="http://tcga.nci/bcr/xml/clinical/cesc/shared/2.5"
13	xmlns:follow_up_v2.0="http://tcga.nci/bcr/xml/clinical/cesc/followup/2.5/2.0"
14	xmlns="http://tcga.nci/bcr/xml/clinical/cesc/2.5"		11	xmlns="http://tcga.nci/bcr/xml/clinical/cesc/2.4"
15	targetNamespace="http://tcga.nci/bcr/xml/clinical/cesc/2.5"		12	targetNamespace="http://tcga.nci/bcr/xml/clinical/cesc/2.4"
31	<xs:import namespace="http://tcga.nci/bcr/xml/utility/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/utility/2.5/TCGA_BCR.Utility.xsd" />	<>	28	<xs:import namespace="http://tcga.nci/bcr/xml/utility/2.4" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/utility/2.4/TCGA_BCR.Utility.xsd" />
32	<xs:import namespace="http://tcga.nci/bcr/xml/administration/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/administration/2.5/TCGA_BCR.Administration.xsd" />		29	<xs:import namespace="http://tcga.nci/bcr/xml/administration/2.4" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/administration/2.4/TCGA_BCR.Administration.xsd" />
33	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/shared/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/shared/2.5/TCGA_BCR.Shared_Clinical_Elements.xsd" />		30	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/shared/2.4" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/shared/2.4/TCGA_BCR.Shared_Clinical_Elements.xsd" />
34	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/radiation/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/radiation/2.5/TCGA_BCR.Radiation.xsd" />		31	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/radiation/2.4" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/radiation/2.4/TCGA_BCR.Radiation.xsd" />
35	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/pharmaceutical/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/pharmaceutical/2.5/TCGA_BCR.Pharmaceutical.xsd" />		32	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/pharmaceutical/2.4" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/pharmaceutical/2.4/TCGA_BCR.Pharmaceutical.xsd" />
36	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/cqcf/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/cqcf/2.5/TCGA_BCR.CQCF.xsd" />
37	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/cesc/shared/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/cesc/shared/2.5/TCGA_BCR.CESC_Clinical_Shared_Datatypes.xsd" />
38	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/cesc/followup/2.5/2.0" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/cesc/followup/2.5/TCGA_BCR.CESC_Clinical_FollowUp_v2.0.xsd" />
56	<xs:element ref="shared:tissue_source_site" />	<>	48	<xs:element ref="shared:tumor_tissue_site" />
57	<xs:element ref="shared:patient_id" />		49	<xs:element ref="shared:prior_diagnosis" />
58	<xs:element ref="shared:bcr_patient_barcode" />		50	<xs:element ref="shared:gender" />
59	<xs:element ref="shared:bcr_patient_uuid" />		51	<xs:element ref="shared:vital_status" />
60	<xs:element ref="shared:informed_consent_verified" />		52
61	<xs:element ref="shared:icd_o_3_site" />
62	<xs:element ref="shared:icd_o_3_histology" />
63	<xs:element ref="shared:icd_10" />
65	<xs:element ref="tissue_prospective_collection_indicator" />	+-
66	<xs:element ref="tissue_retrospective_collection_indicator" />
		<>	63	<xs:choice>
			64	<xs:sequence>
75	<xs:element ref="shared:gender" />		65	<xs:element ref="shared:day_of_last_known_alive" />
76	<xs:element ref="menopause_status" />		66	<xs:element ref="shared:month_of_last_known_alive" />
77	<xs:element ref="shared:height" />		67	<xs:element ref="shared:year_of_last_known_alive" />
			68	</xs:sequence>
78	<xs:element ref="shared:weight" />	<>	70	<xs:element ref="shared:days_to_last_known_alive" />
			71	</xs:choice>
		<>	73	<xs:choice>
			74	<xs:sequence>
79	<xs:element ref="shared:race" />		75	<xs:element ref="shared:day_of_death" />
80	<xs:element ref="shared:ethnicity" />		76	<xs:element ref="shared:month_of_death" />
81	<xs:element ref="shared:prior_diagnosis" />
82	<xs:element ref="shared:pretreatment_history" />		77	<xs:element ref="shared:year_of_death" />
			78	</xs:sequence>
83	<xs:element ref="shared:vital_status" />	<>	80	<xs:element ref="shared:days_to_death" />
			81	</xs:choice>
		-+	93	<xs:element ref="shared:race" />
			94	<xs:element ref="shared:bcr_patient_barcode" />
			95	<xs:element ref="shared:tissue_source_site" />
			96	<xs:element ref="shared:patient_id" />
			97	<xs:element ref="shared:bcr_patient_uuid" />
			98	<xs:element ref="shared:pretreatment_history" />
			99	<xs:element ref="shared:radiation_therapy" />
			100	<xs:element ref="shared:informed_consent_verified" />
			101	<xs:element ref="shared:icd_o_3_site" />
			102	<xs:element ref="shared:icd_o_3_histology" />
			103	<xs:element ref="shared:icd_10" />
94	<xs:element ref="shared:day_of_death" />	<>	107	<xs:element ref="shared:day_of_initial_pathologic_diagnosis" />
95	<xs:element ref="shared:month_of_death" />		108	<xs:element ref="shared:month_of_initial_pathologic_diagnosis" />
			109	</xs:sequence>
		-+	111	<xs:sequence>
			112	<xs:element ref="shared:days_to_initial_pathologic_diagnosis" />
			113	<xs:element ref="shared:age_at_initial_pathologic_diagnosis" />
			114	</xs:sequence>
			115	</xs:choice>
96	<xs:element ref="shared:year_of_death" />	<>	117	<xs:element ref="shared:year_of_initial_pathologic_diagnosis" />
		-+	119	<xs:choice>
			120	<xs:sequence>
			121	<xs:element ref="shared:day_of_new_tumor_event_after_initial_treatment" />
			122	<xs:element ref="shared:month_of_new_tumor_event_after_initial_treatment" />
			123	<xs:element ref="shared:year_of_new_tumor_event_after_initial_treatment" />
		-+	126	<xs:element ref="shared:days_to_new_tumor_event_after_initial_treatment" />
			127	</xs:choice>
98	<xs:element ref="shared:days_to_death" />	<>	129	<xs:element ref="shared:ethnicity" />
			130	<xs:element ref="shared:additional_radiation_therapy" />
			131	<xs:element ref="shared:additional_pharmaceutical_therapy" />
		-+	133	<xs:choice>
			134	<xs:sequence>
			135	<xs:element ref="shared:day_of_additional_surgery_locoregional_procedure" />
			136	<xs:element ref="shared:month_of_additional_surgery_locoregional_procedure" />
			137	<xs:element ref="shared:year_of_additional_surgery_locoregional_procedure" />
			138	</xs:sequence>
		-+	140	<xs:element ref="shared:days_to_additional_surgery_locoregional_procedure" />
		-+	143	<xs:element ref="shared:additional_surgery_metastatic_procedure" />
		-+	145	<xs:element ref="tissue_prospective_collection_indicator" />
			146	<xs:element ref="tissue_retrospective_collection_indicator" />
			147	<xs:element ref="diagnosis_age" />
			148	<xs:element ref="person_menopause_status" />
109	<xs:element ref="tobacco_smoking_history_indicator" />	<>	157	<xs:element ref="patient_smoking_history_category" />
111	<xs:element ref="shared:stopped_smoking_year" />	<>	159	<xs:element ref="stopped_smoking_year" />
112	<xs:element ref="shared:number_pack_years_smoked" />		160	<xs:element ref="person_cigarette_smoking_history_pack_year_value" />
113	<xs:element ref="patient_history_immune_system_and_related_disorders_names" />		161	<xs:element ref="patient_history_immune_system_and_related_disorders_name" />
115	<xs:element ref="shared:eastern_cancer_oncology_group" />	<>	163	<xs:element ref="performance_status_assessment_eastern_cooperative_oncology_group_scale" />
116	<xs:element ref="shared:performance_status_scale_timing" />		164	<xs:element ref="performance_status_assessment_timepoint_category" />
117	<xs:element ref="cesc_shared:performance_status_assessment_timepoint_category_other_text" />		165	<xs:element ref="performance_status_assessment_timepoint_category_other_text" />
128	<xs:element ref="shared:tumor_tissue_site" />	<>
129	<xs:element ref="histological_type" />		178	<xs:element ref="neoplasm_histologic_type_name" />
131	<xs:element ref="shared:neoplasm_histologic_grade" />	<>	180	<xs:element ref="neoplasm_histologic_grade" />
133	<xs:choice>	<>
134	<xs:sequence>
135	<xs:element ref="shared:day_of_initial_pathologic_diagnosis" />
136	<xs:element ref="shared:month_of_initial_pathologic_diagnosis" />		181	<xs:element ref="first_pathologic_diagnosis_biospecimen_acquisition_method_type" />
137	</xs:sequence>
138	<xs:sequence>
139	<xs:element ref="shared:days_to_initial_pathologic_diagnosis" />
140	<xs:element ref="shared:age_at_initial_pathologic_diagnosis" />
141	</xs:sequence>
142	</xs:choice>
143	<xs:element ref="shared:year_of_initial_pathologic_diagnosis" />
145	<xs:element ref="shared:initial_pathologic_diagnosis_method" />	+-
147	<xs:element ref="lymph_node_location_positive_pathology_names" />	<>	183	<xs:element ref="lymph_node_location_positive_pathology_name" />
155	<xs:element ref="shared:primary_lymph_node_presentation_assessment" />	<>
156	<xs:element ref="shared:lymph_node_examined_count" />		190	<xs:element ref="lymph_node_examined_count" />
157	<xs:element ref="shared:number_of_lymphnodes_positive_by_he" />		191	<xs:element ref="positive_finding_lymph_node_hematoxylin_and_eosin_staining_microscopy_count" />
158	<xs:element ref="shared:number_of_lymphnodes_positive_by_ihc" />		192	<xs:element ref="positive_finding_lymph_node_keratin_immunohistochemistry_staining_method_count" />
162	<xs:element ref="shared:ajcc_tumor_stage_code" />	<>	196	<xs:element ref="cervical_tumor_pathologic_t_v7_stage" />
163	<xs:element ref="shared:ajcc_neoplasm_disease_lymph_node_stage" />		197	<xs:element ref="cervical_tumor_pathologic_n_v7_stage" />
164	<xs:element ref="shared:ajcc_cancer_metastasis_stage_code" />		198	<xs:element ref="cervical_tumor_pathologic_m_stage_cervical_cancer_pathologic_distant_metastasis_tnm_finding_v7_stage" />
165	<xs:element ref="shared:gynecologic_figo_staging_system"/>		199	<xs:element ref="cervical_carcinoma_clinical_stage" />
166	<xs:element ref="gynecologic_tumor_grouping_figo_stage" />		200
195	<xs:element ref="human_papillomavirus_types" />	<>	235	<xs:element ref="human_papillomavirus_type" />
		-+	252	<xs:element ref="patient_death_reason" />
			253	<xs:element ref="death_cause_text" />
		-+	257	<xs:element ref="day_of_performance_status_follow_up_score" />
			258	<xs:element ref="month_of_performance_status_follow_up_score_event" />
			259	<xs:element ref="year_of_performance_status_follow_up_score" />
			260	</xs:sequence>
			261	<xs:element ref="days_to_performance_status_follow_up_score" />
			262	</xs:choice>
		-+	265	<xs:element ref="primary_therapy_outcome_success_type" />
			266	<xs:element ref="new_neoplasm_event_type" />
			267	<xs:element ref="new_neoplasm_event_occurrence_anatomic_site" />
			268	<xs:element ref="new_neoplasm_occurrence_anatomic_site_text" />
			269	<xs:element ref="new_neoplasm_event_post_initial_therapy_diagnosis_method_type" />
			270	<xs:element ref="new_neoplasm_event_post_initial_therapy_diagnosis_method_text" />
			271	<xs:element ref="residual_disease_post_new_tumor_event_margin_status" />
			272	<xs:element ref="radiation_therapy_not_administered_reason" />
			273	<xs:element ref="radiation_therapy_not_administered_specify" />
			274	<xs:element ref="brachytherapy_method_type" />
			275	<xs:element ref="brachytherapy_method_other_specify_text" />
		-+	277	<xs:choice>
			278	<xs:sequence>
			279	<xs:element ref="day_of_brachytherapy_begin_occurrence" />
			280	<xs:element ref="month_of_brachytherapy_begin_occurrence" />
			281	<xs:element ref="year_of_brachytherapy_begin_occurrence" />
			282	</xs:sequence>
			283	<xs:element ref="days_to_brachytherapy_begin_occurrence" />
			284	</xs:choice>
		-+	286	<xs:choice>
			287	<xs:sequence>
			288	<xs:element ref="day_of_brachytherapy_end_occurrence" />
			289	<xs:element ref="month_of_brachytherapy_end_occurrence" />
			290	<xs:element ref="year_of_brachytherapy_end_occurrence" />
			291	</xs:sequence>
			292	<xs:element ref="days_to_brachytherapy_end_occurrence" />
			293	</xs:choice>
		-+	295	<xs:element ref="brachytherapy_first_reference_point_administered_total_dose" />
			296	<xs:element ref="brachytherapy_administered_status" />
			297	<xs:element ref="radiation_supplemental" />
			298	<xs:element ref="chemotherapy_regimen_type" />
			299	<xs:element ref="other_chemotherapy_agent_administration_specify" />
		-+	301	<xs:choice>
			302	<xs:sequence>
			303	<xs:element ref="day_of_chemotherapy_start" />
			304	<xs:element ref="month_of_chemotherapy_start" />
			305	<xs:element ref="year_of_chemotherapy_start" />
			306	</xs:sequence>
			307	<xs:element ref="days_to_chemotherapy_start" />
			308	</xs:choice>
		-+	310	<xs:choice>
			311	<xs:sequence>
			312	<xs:element ref="day_of_chemotherapy_end" />
			313	<xs:element ref="month_of_chemotherapy_end" />
			314	<xs:element ref="year_of_chemotherapy_end" />
			315	</xs:sequence>
			316	<xs:element ref="days_to_chemotherapy_end" />
			317	</xs:choice>
		-+	319	<xs:element ref="dose_frequency_text" />
			320	<xs:element ref="agent_total_dose_count" />
			321	<xs:element ref="additional_treatment_completion_success_outcome_type" />
			322	<xs:choice>
			323	<xs:sequence>
219	<xs:element ref="follow_ups" />	+-
222	<xs:element ref="clinical_cqcf" />	+-
227	<xs:element name="follow_ups">	+-
228	<xs:annotation>
229	<xs:documentation xml:lang="en">We are using namespaces and version numbers to distinguish one version of followup from another.</xs:documentation>
230	</xs:annotation>
231	<xs:complexType>
232	<xs:sequence>
233	<xs:element ref="follow_up_v2.0:follow_up_v2.0" minOccurs="0" maxOccurs="unbounded" />
234	</xs:sequence>
235	</xs:complexType>
236	</xs:element>
238	<xs:element name="clinical_cqcf">	<>	338	<xs:element name="radiation_supplemental">
241	<xs:element ref="shared:anatomic_organ_subdivision"/>	+-
242	<xs:element ref="cqcf:consent_or_death_status"/>
245	<xs:choice>	+-
247	<xs:element ref="cqcf:day_of_consent"/>	<>	343	<xs:element ref="rad:day_of_radiation_therapy_start" />
248	<xs:element ref="cqcf:month_of_consent"/>		344	<xs:element ref="rad:month_of_radiation_therapy_start" />
249	<xs:element ref="cqcf:year_of_consent"/>		345	<xs:element ref="rad:year_of_radiation_therapy_start" />
252	<xs:element ref="cqcf:days_to_consent"/>	<>	348	<xs:element ref="rad:days_to_radiation_therapy_start" />
257	<xs:element ref="shared:day_of_death"/>	<>	353	<xs:element ref="rad:day_of_radiation_therapy_end" />
258	<xs:element ref="shared:month_of_death"/>		354	<xs:element ref="rad:month_of_radiation_therapy_end" />
259	<xs:element ref="shared:year_of_death"/>		355	<xs:element ref="rad:year_of_radiation_therapy_end" />
262	<xs:element ref="shared:days_to_death"/>	<>	358	<xs:element ref="rad:days_to_radiation_therapy_end" />
263	</xs:choice>
266	<xs:element ref="cqcf:diagnosis_subtype"/>	<>	361	<xs:element ref="rt_administered_type" />
267	<xs:element ref="shared:prior_diagnosis"/>		362	<xs:element ref="rad:radiation_type_notes" />
268	<xs:element ref="cqcf:history_of_neoadjuvant_treatment"/>		363	<xs:element ref="rt_pelvis_administered_total_dose" />
			364	<xs:element ref="external_beam_radiation_therapy_administered_paraaortic_region_lymph_node_dose" />
269	<xs:element ref="cqcf:normal_tissue_anatomic_site"/>		365	<xs:element ref="external_beam_radiation_therapy_administered_status" />
270	<xs:element ref="cqcf:normal_tissue_proximity"/>		366	<xs:element ref="adjuvant_postoperative_targeted_therapy_administered_indicator" />
271	<xs:element ref="cqcf:tumor_focality"/>		367	<xs:element ref="chemotherapy_negation_radiation_therapy_concurrent_not_administered_reason" />
272	<xs:element ref="cqcf:tumor_type"/>
273	<xs:element ref="cqcf:other_diagnosis"/>
274	<xs:element ref="cqcf:histological_subtype" minOccurs="0"/>
275	<xs:element ref="cqcf:other_anatomic_site" minOccurs="0"/>		368	<xs:element ref="chemotherapy_negation_radiation_therapy_concurrent_administered_text" />
276	<xs:element ref="cqcf:country"/>
310	<xs:extension base="utility:number_or_null">	<>	402	<xs:extension base="xs:decimal">
320	<xs:element name="menopause_status" nillable="true">	<>	412	<xs:element name="person_menopause_status" nillable="true">
369	<xs:extension base="utility:number_or_null">	<>	461	<xs:extension base="xs:decimal">
382	<xs:extension base="utility:number_or_null">	<>	474	<xs:extension base="xs:decimal">
395	<xs:extension base="utility:number_or_null">	<>	487	<xs:extension base="xs:decimal">
408	<xs:extension base="utility:number_or_null">	<>	500	<xs:extension base="xs:decimal">
444	<xs:element name="tobacco_smoking_history_indicator" nillable="true">	<>	536	<xs:element name="patient_smoking_history_category" nillable="true">
464	<xs:extension base="utility:number_or_null">	<>	556	<xs:extension base="xs:decimal">
474	<xs:element name="patient_history_immune_system_and_related_disorders_names">	<>	566	<xs:element name="stopped_smoking_year" nillable="true">
		<>	568	<xs:simpleContent>
			569	<xs:extension base="xs:decimal">
			570	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			571	<xs:attribute name="cde" type="xs:string" default="2228610" />
			572	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			573	<xs:attribute name="tier" type="xs:string" default="2" />
			574	</xs:extension>
			575	</xs:simpleContent>
			576	</xs:complexType>
476	<xs:sequence >		577	</xs:element>
477	<xs:element ref="patient_history_immune_system_and_related_disorders_name" minOccurs="0" maxOccurs="unbounded" />	<>	579	<xs:element name="person_cigarette_smoking_history_pack_year_value" nillable="true">
			580	<xs:complexType>
			581	<xs:simpleContent>
			582	<xs:extension base="xs:decimal">
			583	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			584	<xs:attribute name="cde" type="xs:string" default="2955385" />
			585	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			586	<xs:attribute name="tier" type="xs:string" default="2" />
478	</xs:sequence>		587	</xs:extension>
			588	</xs:simpleContent>
512		<>	622	<xs:element name="performance_status_assessment_eastern_cooperative_oncology_group_scale" nillable="true">
			623	<xs:complexType mixed="true">
			624	<xs:simpleContent>
			625	<xs:restriction base="utility:clinical_res_attributes">
			626	<xs:enumeration value="" />
			627	<xs:enumeration value="0" />
			628	<xs:enumeration value="1" />
			629	<xs:enumeration value="2" />
			630	<xs:enumeration value="3" />
			631	<xs:enumeration value="4" />
			632	<xs:enumeration value="5" />
			633	<xs:attribute name="cde" type="xs:string" default="88" />
			634	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			635	<xs:attribute name="tier" type="xs:string" default="2" />
			636	</xs:restriction>
			637	</xs:simpleContent>
			638	</xs:complexType>
			639	</xs:element>
		-+	641	<xs:element name="performance_status_assessment_timepoint_category" nillable="true">
			642	<xs:complexType mixed="true">
			643	<xs:simpleContent>
			644	<xs:restriction base="utility:clinical_res_attributes">
			645	<xs:enumeration value="" />
			646	<xs:enumeration value="Post-adjuvant therapy" />
			647	<xs:enumeration value="Pre-adjuvant therapy" />
			648	<xs:enumeration value="Preoperative" />
			649	<xs:enumeration value="Other" />
			650	<xs:enumeration value="5" />
			651	<xs:attribute name="cde" type="xs:string" default="2792763" />
			652	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			653	<xs:attribute name="tier" type="xs:string" default="2" />
			654	</xs:restriction>
			655	</xs:simpleContent>
			656	</xs:complexType>
			657	</xs:element>
		-+	659	<xs:element name="performance_status_assessment_timepoint_category_other_text" nillable="true">
			660	<xs:complexType>
			661	<xs:simpleContent>
			662	<xs:extension base="xs:string">
			663	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			664	<xs:attribute name="cde" type="xs:string" default="3151756" />
			665	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			666	<xs:attribute name="tier" type="xs:string" default="2" />
			667	</xs:extension>
			668	</xs:simpleContent>
			669	</xs:complexType>
			670	</xs:element>
584	<xs:element name="histological_type" nillable="true">	<>	740	<xs:element name="neoplasm_histologic_type_name" nillable="true">
		-+	770	<xs:element name="neoplasm_histologic_grade" nillable="true">
			771	<xs:complexType mixed="true">
			772	<xs:simpleContent>
			773	<xs:restriction base="utility:clinical_res_attributes">
			774	<xs:enumeration value="" />
			775	<xs:enumeration value="G1" />
			776	<xs:enumeration value="G2" />
			777	<xs:enumeration value="G3" />
			778	<xs:enumeration value="G4" />
			779	<xs:enumeration value="GX" />
			780	<xs:attribute name="cde" type="xs:string" default="2785839" />
			781	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			782	<xs:attribute name="tier" type="xs:string" default="1" />
			783	</xs:restriction>
			784	</xs:simpleContent>
			785	</xs:complexType>
			786	</xs:element>
		-+	788	<xs:element name="first_pathologic_diagnosis_biospecimen_acquisition_method_type" nillable="true">
			789	<xs:complexType mixed="true">
			790	<xs:simpleContent>
			791	<xs:restriction base="utility:clinical_res_attributes">
			792	<xs:enumeration value="" />
			793	<xs:enumeration value="Cytology (e.g. Peritoneal or pleural fluid)" />
			794	<xs:enumeration value="Biopsy (cervical / CT-guided / Other)" />
			795	<xs:enumeration value="Cone Biopsy / LEEP" />
			796	<xs:enumeration value="Lymph node sampling or dissection" />
			797	<xs:enumeration value="Other method, specify:" />
			798	<xs:attribute name="cde" type="xs:string" default="2757941" />
			799	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			800	<xs:attribute name="tier" type="xs:string" default="2" />
			801	</xs:restriction>
			802	</xs:simpleContent>
			803	</xs:complexType>
			804	</xs:element>
627	<xs:element name="lymph_node_location_positive_pathology_names">	+-
628	<xs:complexType>
629	<xs:sequence >
630	<xs:element ref="lymph_node_location_positive_pathology_name" minOccurs="0" maxOccurs="unbounded" />
631	</xs:sequence>
632	</xs:complexType>
633	</xs:element>
		-+	924	<xs:element name="lymph_node_examined_count" nillable="true">
			925	<xs:complexType>
			926	<xs:simpleContent>
			927	<xs:extension base="xs:integer">
			928	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			929	<xs:attribute name="cde" type="xs:string" default="3" />
			930	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
			931	<xs:attribute name="tier" type="xs:string" default="1" />
			932	</xs:extension>
			933	</xs:simpleContent>
			934	</xs:complexType>
			935	</xs:element>
		-+	937	<xs:element name="positive_finding_lymph_node_hematoxylin_and_eosin_staining_microscopy_count" nillable="true">
			938	<xs:complexType>
			939	<xs:simpleContent>
			940	<xs:extension base="xs:integer">
			941	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			942	<xs:attribute name="cde" type="xs:string" default="3086388" />
			943	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
			944	<xs:attribute name="tier" type="xs:string" default="1" />
			945	</xs:extension>
			946	</xs:simpleContent>
			947	</xs:complexType>
			948	</xs:element>
		-+	950	<xs:element name="positive_finding_lymph_node_keratin_immunohistochemistry_staining_method_count" nillable="true">
			951	<xs:complexType>
			952	<xs:simpleContent>
			953	<xs:extension base="xs:integer">
			954	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			955	<xs:attribute name="cde" type="xs:string" default="3086383" />
			956	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
			957	<xs:attribute name="tier" type="xs:string" default="1" />
			958	</xs:extension>
			959	</xs:simpleContent>
			960	</xs:complexType>
			961	</xs:element>
		-+	993	<xs:element name="cervical_tumor_pathologic_t_v7_stage" nillable="true">
			994	<xs:complexType mixed="true">
			995	<xs:simpleContent>
			996	<xs:restriction base="utility:clinical_res_attributes">
			997	<xs:enumeration value="" />
			998	<xs:enumeration value="TX" />
			999	<xs:enumeration value="T0" />
			1000	<xs:enumeration value="Tis" />
			1001	<xs:enumeration value="Tis (DCIS)" />
			1002	<xs:enumeration value="Tis (LCIS)" />
			1003	<xs:enumeration value="Tis (Paget's)" />
			1004	<xs:enumeration value="T1mi" />
			1005	<xs:enumeration value="T1" />
			1006	<xs:enumeration value="T1a" />
			1007	<xs:enumeration value="T1b" />
			1008	<xs:enumeration value="T1b1" />
			1009	<xs:enumeration value="T1b2" />
			1010	<xs:enumeration value="T1c" />
			1011	<xs:enumeration value="T2" />
			1012	<xs:enumeration value="T2a" />
			1013	<xs:enumeration value="T2b" />
			1014	<xs:enumeration value="T2c" />
			1015	<xs:enumeration value="Ta" />
			1016	<xs:enumeration value="T3" />
			1017	<xs:enumeration value="T3a" />
			1018	<xs:enumeration value="T3b" />
			1019	<xs:enumeration value="T3c" />
			1020	<xs:enumeration value="T4" />
			1021	<xs:enumeration value="T4a" />
			1022	<xs:enumeration value="T4b" />
			1023	<xs:enumeration value="T4c" />
			1024	<xs:enumeration value="T4d" />
			1025	<xs:enumeration value="T1a1" />
			1026	<xs:enumeration value="T1a2" />
			1027	<xs:enumeration value="T2a1" />
			1028	<xs:enumeration value="T2a2" />
		-+	1030	<xs:attribute name="cde" type="xs:string" default="3045435" />
			1031	<xs:attribute name="xsd_ver" type="xs:string" default="2.4.1" />
			1032	<xs:attribute name="tier" type="xs:string" default="1" />
			1033	</xs:restriction>
			1034	</xs:simpleContent>
			1035	</xs:complexType>
			1036	</xs:element>
771	<xs:element name="gynecologic_tumor_grouping_figo_stage" nillable="true">	<>	1038	<xs:element name="cervical_tumor_pathologic_n_v7_stage" nillable="true">
		-+	1043	<xs:enumeration value="NX" />
			1044	<xs:enumeration value="N0" />
			1045	<xs:enumeration value="N0 (i-)" />
			1046	<xs:enumeration value="N0 (i+)" />
			1047	<xs:enumeration value="N0 (mol-)" />
			1048	<xs:enumeration value="N0 (mol+)" />
			1049	<xs:enumeration value="N1" />
			1050	<xs:enumeration value="N1mi" />
			1051	<xs:enumeration value="N1a" />
			1052	<xs:enumeration value="N1b" />
			1053	<xs:enumeration value="N1bI" />
			1054	<xs:enumeration value="N1bII" />
			1055	<xs:enumeration value="N1bIII" />
			1056	<xs:enumeration value="N1bIV" />
			1057	<xs:enumeration value="N1c" />
			1058	<xs:enumeration value="N2" />
			1059	<xs:enumeration value="N2a" />
			1060	<xs:enumeration value="N2b" />
			1061	<xs:enumeration value="N3" />
			1062	<xs:enumeration value="N3a" />
			1063	<xs:enumeration value="N3b" />
			1064	<xs:enumeration value="N3c" />
			1065	<xs:enumeration value="N4" />
			1066	<xs:attribute name="cde" type="xs:string" default="3203106" />
			1067	<xs:attribute name="xsd_ver" type="xs:string" default="2.4.1" />
			1068	<xs:attribute name="tier" type="xs:string" default="1" />
			1069	</xs:restriction>
			1070	</xs:simpleContent>
			1071	</xs:complexType>
			1072	</xs:element>
		-+	1074	<xs:element name="cervical_tumor_pathologic_m_stage_cervical_cancer_pathologic_distant_metastasis_tnm_finding_v7_stage" nillable="true">
			1075	<xs:complexType mixed="true">
			1076	<xs:simpleContent>
			1077	<xs:restriction base="utility:clinical_res_attributes">
			1078	<xs:enumeration value="" />
			1079	<xs:enumeration value="MX" />
			1080	<xs:enumeration value="M0" />
			1081	<xs:enumeration value="M1" />
			1082	<xs:enumeration value="M1a" />
			1083	<xs:enumeration value="M1b" />
			1084	<xs:enumeration value="M1c" />
			1085	<xs:enumeration value="cM0 (i+)" />
			1086	<xs:attribute name="cde" type="xs:string" default="3045439" />
			1087	<xs:attribute name="xsd_ver" type="xs:string" default="2.4.1" />
			1088	<xs:attribute name="tier" type="xs:string" default="1" />
			1089	</xs:restriction>
			1090	</xs:simpleContent>
			1091	</xs:complexType>
			1092	</xs:element>
		-+	1094	<xs:element name="cervical_carcinoma_clinical_stage" nillable="true">
			1095	<xs:complexType mixed="true">
			1096	<xs:simpleContent>
			1097	<xs:restriction base="utility:clinical_res_attributes">
			1098	<xs:enumeration value="" />
779	<xs:enumeration value="Stage IA1" />	+-
780	<xs:enumeration value="Stage IA2" />
782	<xs:enumeration value="Stage IB1" />	+-
783	<xs:enumeration value="Stage IB2" />
784	<xs:enumeration value="Stage IC" />
786	<xs:enumeration value="Stage IIA" />	+-
787	<xs:enumeration value="Stage IIB" />
797	<xs:attribute name="cde" type="xs:string" default="3225684" />	<>	1113	<xs:attribute name="cde" type="xs:string" default="2753341" />
798	<xs:attribute name="xsd_ver" type="xs:string" default="2.5" />		1114	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
859	<xs:extension base="utility:number_or_null">	<>	1175	<xs:extension base="xs:decimal">
971	<xs:element name="human_papillomavirus_types">	+-
972	<xs:complexType>
973	<xs:sequence >
974	<xs:element ref="human_papillomavirus_type" minOccurs="0" maxOccurs="unbounded" />
975	</xs:sequence>
976	</xs:complexType>
977	</xs:element>
1074	<xs:extension base="utility:number_or_null">	<>	1382	<xs:extension base="xs:decimal">
		-+	1444	<xs:element name="patient_death_reason" nillable="true">
			1445	<xs:complexType mixed="true">
			1446	<xs:simpleContent>
			1447	<xs:restriction base="utility:clinical_res_attributes">
			1448	<xs:enumeration value="" />
			1449	<xs:enumeration value="Cervical Cancer" />
			1450	<xs:enumeration value="Other, specify" />
			1451	<xs:attribute name="cde" type="xs:string" default="2554674" />
			1452	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			1453	<xs:attribute name="tier" type="xs:string" default="2" />
			1454	</xs:restriction>
			1455	</xs:simpleContent>
			1456	</xs:complexType>
			1457	</xs:element>
		-+	1459	<xs:element name="death_cause_text" nillable="true">
			1460	<xs:complexType>
			1461	<xs:simpleContent>
			1462	<xs:extension base="xs:string">
			1463	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			1464	<xs:attribute name="cde" type="xs:string" default="2004150" />
			1465	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			1466	<xs:attribute name="tier" type="xs:string" default="2" />
			1467	</xs:extension>
			1468	</xs:simpleContent>
			1469	</xs:complexType>
			1470	</xs:element>
		-+	1472	<xs:element name="day_of_performance_status_follow_up_score" nillable="true">
			1473	<xs:complexType>
			1474	<xs:simpleContent>
			1475	<xs:extension base="utility:generic_day">
			1476	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			1477	<xs:attribute name="cde" type="xs:string" default="3121372" />
			1478	<xs:attribute name="xsd_ver" type="xs:string" default="2.4" />
			1479	<xs:attribute name="tier" type="xs:string" default="2" />
			1480	</xs:extension>
			1481	</xs:simpleContent>
			1482	</xs:complexType>
			1483	</xs:element>
		-+	1485	<xs:element name="month_of_performance_status_follow_up_score_event" nillable="true">
			1486	<xs:complexType>
			1487	<xs:simpleContent>
			1488	<xs:extension base="utility:generic_month">
			1489	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			1490	<xs:attribute name="cde" type="xs:string" default="3121370" />
			1491	<xs:attribute name="xsd_ver" type="xs:string" default="2.4" />
			1492	<xs:attribute name="tier" type="xs:string" default="2" />
			1493	</xs:extension>
			1494	</xs:simpleContent>
			1495	</xs:complexType>
			1496	</xs:element>
		-+	1498	<xs:element name="year_of_performance_status_follow_up_score" nillable="true">
			1499	<xs:complexType>
			1500	<xs:simpleContent>
			1501	<xs:extension base="utility:generic_year">
			1502	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			1503	<xs:attribute name="cde" type="xs:string" default="3121374" />
			1504	<xs:attribute name="xsd_ver" type="xs:string" default="2.4" />
			1505	<xs:attribute name="tier" type="xs:string" default="2" />
			1506	</xs:extension>
			1507	</xs:simpleContent>
			1508	</xs:complexType>
			1509	</xs:element>
		-+	1511	<xs:element name="days_to_performance_status_follow_up_score">
			1512	<xs:complexType mixed="true">
			1513	<xs:simpleContent>
			1514	<xs:restriction base="utility:clinical_res_attributes">
			1515	<xs:attribute name="cde" type="xs:string" default="" />
			1516	<xs:attribute name="xsd_ver" type="xs:string" default="2.4" />
			1517	<xs:attribute name="tier" type="xs:string" default="1" />
			1518	</xs:restriction>
			1519	</xs:simpleContent>
			1520	</xs:complexType>
			1521	</xs:element>
		-+	1523	<xs:element name="primary_therapy_outcome_success_type" nillable="true">
			1524	<xs:complexType mixed="true">
			1525	<xs:simpleContent>
			1526	<xs:restriction base="utility:clinical_res_attributes">
			1527	<xs:enumeration value="" />
			1528	<xs:enumeration value="Progressive Disease" />
			1529	<xs:enumeration value="Stable Disease" />
			1530	<xs:enumeration value="Partial Response" />
			1531	<xs:enumeration value="Complete Remission/Response" />
			1532	<xs:enumeration value="Not Applicable" />
			1533	<xs:attribute name="cde" type="xs:string" default="2786727" />
			1534	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			1535	<xs:attribute name="tier" type="xs:string" default="1" />
			1536	</xs:restriction>
			1537	</xs:simpleContent>
			1538	</xs:complexType>
			1539	</xs:element>
		-+	1541	<xs:element name="new_neoplasm_event_type" nillable="true">
			1542	<xs:complexType mixed="true">
			1543	<xs:simpleContent>
			1544	<xs:restriction base="utility:clinical_res_attributes">
			1545	<xs:enumeration value="" />
			1546	<xs:enumeration value="Locoregional Disease" />
			1547	<xs:enumeration value="New Primary Tumor" />
			1548	<xs:enumeration value="Metastatic" />
			1549	<xs:enumeration value="Not Applicable" />
			1550	<xs:attribute name="cde" type="xs:string" default="3119721" />
			1551	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			1552	<xs:attribute name="tier" type="xs:string" default="2" />
			1553	</xs:restriction>
			1554	</xs:simpleContent>
			1555	</xs:complexType>
			1556	</xs:element>
		-+	1558	<xs:element name="new_neoplasm_event_occurrence_anatomic_site" nillable="true">
			1559	<xs:complexType mixed="true">
			1560	<xs:simpleContent>
			1561	<xs:restriction base="utility:clinical_res_attributes">
			1562	<xs:enumeration value="" />
			1563	<xs:enumeration value="Cervix" />
			1564	<xs:enumeration value="Head &amp; Neck" />
			1565	<xs:enumeration value="Lung" />
			1566	<xs:enumeration value="Vulva" />
			1567	<xs:enumeration value="Anus" />
			1568	<xs:enumeration value="Other, specify" />
			1569	<xs:attribute name="cde" type="xs:string" default="3108271" />
			1570	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			1571	<xs:attribute name="tier" type="xs:string" default="2" />
			1572	</xs:restriction>
			1573	</xs:simpleContent>
			1574	</xs:complexType>
			1575	</xs:element>
		-+	1577	<xs:element name="new_neoplasm_occurrence_anatomic_site_text" nillable="true">
			1578	<xs:complexType>
			1579	<xs:simpleContent>
			1580	<xs:extension base="xs:string">
			1581	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			1582	<xs:attribute name="cde" type="xs:string" default="3128033" />
			1583	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			1584	<xs:attribute name="tier" type="xs:string" default="2" />
			1585	</xs:extension>
			1586	</xs:simpleContent>
			1587	</xs:complexType>
			1588	</xs:element>
		-+	1590	<xs:element name="new_neoplasm_event_post_initial_therapy_diagnosis_method_type" nillable="true">
			1591	<xs:complexType mixed="true">
			1592	<xs:simpleContent>
			1593	<xs:restriction base="utility:clinical_res_attributes">
			1594	<xs:enumeration value="" />
			1595	<xs:enumeration value="Tumor Resection" />
			1596	<xs:enumeration value="Cytology" />
			1597	<xs:enumeration value="Not Applicable" />
			1598	<xs:enumeration value="Other, specify" />
			1599	<xs:attribute name="cde" type="xs:string" default="3151113" />
			1600	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			1601	<xs:attribute name="tier" type="xs:string" default="2" />
			1602	</xs:restriction>
			1603	</xs:simpleContent>
			1604	</xs:complexType>
			1605	</xs:element>
		-+	1607	<xs:element name="new_neoplasm_event_post_initial_therapy_diagnosis_method_text" nillable="true">
			1608	<xs:complexType>
			1609	<xs:simpleContent>
			1610	<xs:extension base="xs:string">
			1611	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			1612	<xs:attribute name="cde" type="xs:string" default="3151116" />
			1613	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			1614	<xs:attribute name="tier" type="xs:string" default="2" />
			1615	</xs:extension>
			1616	</xs:simpleContent>
			1617	</xs:complexType>
			1618	</xs:element>
		-+	1620	<xs:element name="residual_disease_post_new_tumor_event_margin_status" nillable="true">
			1621	<xs:complexType mixed="true">
			1622	<xs:simpleContent>
			1623	<xs:restriction base="utility:clinical_res_attributes">
			1624	<xs:enumeration value="" />
			1625	<xs:enumeration value="R0" />
			1626	<xs:enumeration value="R1" />
			1627	<xs:enumeration value="R2" />
			1628	<xs:enumeration value="RX" />
			1629	<xs:attribute name="cde" type="xs:string" default="3104061" />
			1630	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			1631	<xs:attribute name="tier" type="xs:string" default="2" />
			1632	</xs:restriction>
			1633	</xs:simpleContent>
			1634	</xs:complexType>
			1635	</xs:element>
		-+	1637	<xs:element name="radiation_therapy_not_administered_reason" nillable="true">
			1638	<xs:complexType mixed="true">
			1639	<xs:simpleContent>
			1640	<xs:restriction base="utility:clinical_res_attributes">
			1641	<xs:enumeration value="" />
			1642	<xs:enumeration value="Adverse event/complications" />
			1643	<xs:enumeration value="Scheduling problems" />
			1644	<xs:enumeration value="Participant refusal" />
			1645	<xs:enumeration value="Not done per treating physician discretion" />
			1646	<xs:enumeration value="Other" />
			1647	<xs:attribute name="cde" type="xs:string" default="2733266" />
			1648	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			1649	<xs:attribute name="tier" type="xs:string" default="2" />
			1650	</xs:restriction>
			1651	</xs:simpleContent>
			1652	</xs:complexType>
			1653	</xs:element>
		-+	1655	<xs:element name="radiation_therapy_not_administered_specify" nillable="true">
			1656	<xs:complexType>
			1657	<xs:simpleContent>
			1658	<xs:extension base="xs:string">
			1659	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			1660	<xs:attribute name="cde" type="xs:string" default="2733267" />
			1661	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			1662	<xs:attribute name="tier" type="xs:string" default="2" />
			1663	</xs:extension>
			1664	</xs:simpleContent>
			1665	</xs:complexType>
			1666	</xs:element>
		-+	1668	<xs:element name="brachytherapy_method_type" nillable="true">
			1669	<xs:complexType mixed="true">
			1670	<xs:simpleContent>
			1671	<xs:restriction base="utility:clinical_res_attributes">
			1672	<xs:enumeration value="" />
			1673	<xs:enumeration value="LDR" />
			1674	<xs:enumeration value="HDR" />
			1675	<xs:enumeration value="Other" />
			1676	<xs:attribute name="cde" type="xs:string" default="2966127" />
			1677	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			1678	<xs:attribute name="tier" type="xs:string" default="2" />
			1679	</xs:restriction>
			1680	</xs:simpleContent>
			1681	</xs:complexType>
			1682	</xs:element>
		-+	1684	<xs:element name="brachytherapy_method_other_specify_text" nillable="true">
			1685	<xs:complexType>
			1686	<xs:simpleContent>
			1687	<xs:extension base="xs:string">
			1688	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			1689	<xs:attribute name="cde" type="xs:string" default="3150976" />
			1690	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			1691	<xs:attribute name="tier" type="xs:string" default="2" />
			1692	</xs:extension>
			1693	</xs:simpleContent>
			1694	</xs:complexType>
			1695	</xs:element>
		-+	1697	<xs:element name="day_of_brachytherapy_begin_occurrence" nillable="true">
			1698	<xs:complexType>
			1699	<xs:simpleContent>
			1700	<xs:extension base="utility:generic_day">
			1701	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			1702	<xs:attribute name="cde" type="xs:string" default="3150980" />
			1703	<xs:attribute name="xsd_ver" type="xs:string" default="2.4" />
			1704	<xs:attribute name="tier" type="xs:string" default="2" />
			1705	</xs:extension>
			1706	</xs:simpleContent>
			1707	</xs:complexType>
			1708	</xs:element>
		-+	1710	<xs:element name="month_of_brachytherapy_begin_occurrence" nillable="true">
			1711	<xs:complexType>
			1712	<xs:simpleContent>
			1713	<xs:extension base="utility:generic_month">
			1714	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			1715	<xs:attribute name="cde" type="xs:string" default="3150979" />
			1716	<xs:attribute name="xsd_ver" type="xs:string" default="2.4" />
			1717	<xs:attribute name="tier" type="xs:string" default="2" />
			1718	</xs:extension>
			1719	</xs:simpleContent>
			1720	</xs:complexType>
			1721	</xs:element>
		-+	1723	<xs:element name="year_of_brachytherapy_begin_occurrence" nillable="true">
			1724	<xs:complexType>
			1725	<xs:simpleContent>
			1726	<xs:extension base="utility:generic_year">
			1727	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			1728	<xs:attribute name="cde" type="xs:string" default="3150981" />
			1729	<xs:attribute name="xsd_ver" type="xs:string" default="2.4" />
			1730	<xs:attribute name="tier" type="xs:string" default="2" />
			1731	</xs:extension>
			1732	</xs:simpleContent>
			1733	</xs:complexType>
			1734	</xs:element>
		-+	1736	<xs:element name="days_to_brachytherapy_begin_occurrence">
			1737	<xs:complexType mixed="true">
			1738	<xs:simpleContent>
			1739	<xs:restriction base="utility:clinical_res_attributes">
			1740	<xs:attribute name="cde" type="xs:string" default="" />
			1741	<xs:attribute name="xsd_ver" type="xs:string" default="2.4" />
			1742	<xs:attribute name="tier" type="xs:string" default="1" />
			1743	</xs:restriction>
			1744	</xs:simpleContent>
			1745	</xs:complexType>
			1746	</xs:element>
		-+	1748	<xs:element name="day_of_brachytherapy_end_occurrence" nillable="true">
			1749	<xs:complexType>
			1750	<xs:simpleContent>
			1751	<xs:extension base="utility:generic_day">
			1752	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			1753	<xs:attribute name="cde" type="xs:string" default="3151011" />
			1754	<xs:attribute name="xsd_ver" type="xs:string" default="2.4" />
			1755	<xs:attribute name="tier" type="xs:string" default="2" />
			1756	</xs:extension>
			1757	</xs:simpleContent>
			1758	</xs:complexType>
			1759	</xs:element>
		-+	1761	<xs:element name="month_of_brachytherapy_end_occurrence" nillable="true">
			1762	<xs:complexType>
			1763	<xs:simpleContent>
			1764	<xs:extension base="utility:generic_month">
			1765	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			1766	<xs:attribute name="cde" type="xs:string" default="3151002" />
			1767	<xs:attribute name="xsd_ver" type="xs:string" default="2.4" />
			1768	<xs:attribute name="tier" type="xs:string" default="2" />
			1769	</xs:extension>
			1770	</xs:simpleContent>
			1771	</xs:complexType>
			1772	</xs:element>
		-+	1774	<xs:element name="year_of_brachytherapy_end_occurrence" nillable="true">
			1775	<xs:complexType>
			1776	<xs:simpleContent>
			1777	<xs:extension base="utility:generic_year">
			1778	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			1779	<xs:attribute name="cde" type="xs:string" default="3151068" />
			1780	<xs:attribute name="xsd_ver" type="xs:string" default="2.4" />
			1781	<xs:attribute name="tier" type="xs:string" default="2" />
			1782	</xs:extension>
			1783	</xs:simpleContent>
			1784	</xs:complexType>
			1785	</xs:element>
		-+	1787	<xs:element name="days_to_brachytherapy_end_occurrence">
			1788	<xs:complexType mixed="true">
			1789	<xs:simpleContent>
			1790	<xs:restriction base="utility:clinical_res_attributes">
			1791	<xs:attribute name="cde" type="xs:string" default="" />
			1792	<xs:attribute name="xsd_ver" type="xs:string" default="2.4" />
			1793	<xs:attribute name="tier" type="xs:string" default="1" />
			1794	</xs:restriction>
			1795	</xs:simpleContent>
			1796	</xs:complexType>
			1797	</xs:element>
		-+	1799	<xs:element name="brachytherapy_first_reference_point_administered_total_dose" nillable="true">
			1800	<xs:complexType>
			1801	<xs:simpleContent>
			1802	<xs:extension base="xs:decimal">
			1803	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			1804	<xs:attribute name="cde" type="xs:string" default="3151100" />
			1805	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			1806	<xs:attribute name="tier" type="xs:string" default="2" />
			1807	<xs:attribute name="units" type="xs:string" fixed="cGy"/>
			1808	</xs:extension>
			1809	</xs:simpleContent>
			1810	</xs:complexType>
			1811	</xs:element>
		-+	1813	<xs:element name="brachytherapy_administered_status" nillable="true">
			1814	<xs:complexType mixed="true">
			1815	<xs:simpleContent>
			1816	<xs:restriction base="utility:clinical_res_attributes">
			1817	<xs:enumeration value="" />
			1818	<xs:enumeration value="Completed as planned" />
			1819	<xs:enumeration value="Treatment not completed" />
			1820	<xs:attribute name="cde" type="xs:string" default="3151103" />
			1821	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			1822	<xs:attribute name="tier" type="xs:string" default="2" />
			1823	</xs:restriction>
			1824	</xs:simpleContent>
			1825	</xs:complexType>
			1826	</xs:element>
		-+	1828	<xs:element name="rt_administered_type" nillable="true">
			1829	<xs:complexType mixed="true">
			1830	<xs:simpleContent>
			1831	<xs:restriction base="utility:clinical_res_attributes">
			1832	<xs:enumeration value="" />
			1833	<xs:enumeration value="3D conformal" />
			1834	<xs:enumeration value="IMRT" />
			1835	<xs:enumeration value="External beam radiation" />
			1836	<xs:enumeration value="Other" />
			1837	<xs:attribute name="cde" type="xs:string" default="61468" />
			1838	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			1839	<xs:attribute name="tier" type="xs:string" default="2" />
			1840	</xs:restriction>
			1841	</xs:simpleContent>
			1842	</xs:complexType>
			1843	</xs:element>
		-+	1845	<xs:element name="rt_pelvis_administered_total_dose" nillable="true">
			1846	<xs:complexType>
			1847	<xs:simpleContent>
			1848	<xs:extension base="xs:decimal">
			1849	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			1850	<xs:attribute name="cde" type="xs:string" default="3006" />
			1851	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			1852	<xs:attribute name="tier" type="xs:string" default="2" />
			1853	<xs:attribute name="units" type="xs:string" fixed="cGy"/>
			1854	</xs:extension>
			1855	</xs:simpleContent>
			1856	</xs:complexType>
			1857	</xs:element>
		-+	1859	<xs:element name="external_beam_radiation_therapy_administered_paraaortic_region_lymph_node_dose" nillable="true">
			1860	<xs:complexType>
			1861	<xs:simpleContent>
			1862	<xs:extension base="xs:decimal">
			1863	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			1864	<xs:attribute name="cde" type="xs:string" default="3151106" />
			1865	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			1866	<xs:attribute name="tier" type="xs:string" default="2" />
			1867	<xs:attribute name="units" type="xs:string" fixed="cGy"/>
			1868	</xs:extension>
			1869	</xs:simpleContent>
			1870	</xs:complexType>
			1871	</xs:element>
		-+	1873	<xs:element name="external_beam_radiation_therapy_administered_status" nillable="true">
			1874	<xs:complexType mixed="true">
			1875	<xs:simpleContent>
			1876	<xs:restriction base="utility:clinical_res_attributes">
			1877	<xs:enumeration value="" />
			1878	<xs:enumeration value="Treatment not completed" />
			1879	<xs:enumeration value="Completed as Planned" />
			1880	<xs:attribute name="cde" type="xs:string" default="3151107" />
			1881	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			1882	<xs:attribute name="tier" type="xs:string" default="2" />
			1883	</xs:restriction>
			1884	</xs:simpleContent>
			1885	</xs:complexType>
			1886	</xs:element>
		-+	1888	<xs:element name="adjuvant_postoperative_targeted_therapy_administered_indicator" nillable="true">
			1889	<xs:complexType>
			1890	<xs:simpleContent>
			1891	<xs:extension base="utility:yes_or_no">
			1892	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			1893	<xs:attribute name="cde" type="xs:string" default="2785850" />
			1894	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			1895	<xs:attribute name="tier" type="xs:string" default="2" />
			1896	</xs:extension>
			1897	</xs:simpleContent>
			1898	</xs:complexType>
			1899	</xs:element>
		-+	1901	<xs:element name="chemotherapy_negation_radiation_therapy_concurrent_not_administered_reason" nillable="true">
			1902	<xs:complexType mixed="true">
			1903	<xs:simpleContent>
			1904	<xs:restriction base="utility:clinical_res_attributes">
			1905	<xs:enumeration value="" />
			1906	<xs:enumeration value="Adverse event/ complications" />
			1907	<xs:enumeration value="Scheduling problems" />
			1908	<xs:enumeration value="Participant refusal" />
			1909	<xs:enumeration value="Not done per treating physicians discretion" />
			1910	<xs:enumeration value="Other" />
			1911	<xs:attribute name="cde" type="xs:string" default="3151120" />
			1912	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			1913	<xs:attribute name="tier" type="xs:string" default="2" />
			1914	</xs:restriction>
			1915	</xs:simpleContent>
			1916	</xs:complexType>
			1917	</xs:element>
		-+	1919	<xs:element name="chemotherapy_negation_radiation_therapy_concurrent_administered_text" nillable="true">
			1920	<xs:complexType>
			1921	<xs:simpleContent>
			1922	<xs:extension base="xs:string">
			1923	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			1924	<xs:attribute name="cde" type="xs:string" default="3151824" />
			1925	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			1926	<xs:attribute name="tier" type="xs:string" default="2" />
			1927	</xs:extension>
			1928	</xs:simpleContent>
			1929	</xs:complexType>
			1930	</xs:element>
		-+	1932	<xs:element name="chemotherapy_regimen_type" nillable="true">
			1933	<xs:complexType mixed="true">
			1934	<xs:simpleContent>
			1935	<xs:restriction base="utility:clinical_res_attributes">
			1936	<xs:enumeration value="" />
			1937	<xs:enumeration value="Carboplatin" />
			1938	<xs:enumeration value="Cisplatin" />
			1939	<xs:enumeration value="Other" />
			1940	<xs:attribute name="cde" type="xs:string" default="2007212" />
			1941	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			1942	<xs:attribute name="tier" type="xs:string" default="2" />
			1943	</xs:restriction>
			1944	</xs:simpleContent>
			1945	</xs:complexType>
			1946	</xs:element>
		-+	1948	<xs:element name="other_chemotherapy_agent_administration_specify" nillable="true">
			1949	<xs:complexType>
			1950	<xs:simpleContent>
			1951	<xs:extension base="xs:string">
			1952	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			1953	<xs:attribute name="cde" type="xs:string" default="2426129" />
			1954	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			1955	<xs:attribute name="tier" type="xs:string" default="2" />
			1956	</xs:extension>
			1957	</xs:simpleContent>
			1958	</xs:complexType>
			1959	</xs:element>
		-+	1961	<xs:element name="day_of_chemotherapy_start" nillable="true">
			1962	<xs:complexType>
			1963	<xs:simpleContent>
			1964	<xs:extension base="utility:generic_day">
			1965	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			1966	<xs:attribute name="cde" type="xs:string" default="2897052" />
			1967	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			1968	<xs:attribute name="tier" type="xs:string" default="2" />
			1969	</xs:extension>
			1970	</xs:simpleContent>
			1971	</xs:complexType>
			1972	</xs:element>
		-+	1974	<xs:element name="month_of_chemotherapy_start" nillable="true">
			1975	<xs:complexType>
			1976	<xs:simpleContent>
			1977	<xs:extension base="utility:generic_month">
			1978	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			1979	<xs:attribute name="cde" type="xs:string" default="2897050" />
			1980	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			1981	<xs:attribute name="tier" type="xs:string" default="2" />
			1982	</xs:extension>
			1983	</xs:simpleContent>
			1984	</xs:complexType>
			1985	</xs:element>
		-+	1987	<xs:element name="year_of_chemotherapy_start" nillable="true">
			1988	<xs:complexType>
			1989	<xs:simpleContent>
			1990	<xs:extension base="utility:generic_year">
			1991	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			1992	<xs:attribute name="cde" type="xs:string" default="2897054" />
			1993	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			1994	<xs:attribute name="tier" type="xs:string" default="2" />
			1995	</xs:extension>
			1996	</xs:simpleContent>
			1997	</xs:complexType>
			1998	</xs:element>
		-+	2000	<xs:element name="days_to_chemotherapy_start">
			2001	<xs:complexType mixed="true">
			2002	<xs:simpleContent>
			2003	<xs:restriction base="utility:clinical_res_attributes">
			2004	<xs:attribute name="cde" type="xs:string" default="" />
			2005	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			2006	<xs:attribute name="tier" type="xs:string" default="1" />
			2007	</xs:restriction>
			2008	</xs:simpleContent>
			2009	</xs:complexType>
			2010	</xs:element>
		-+	2012	<xs:element name="day_of_chemotherapy_end" nillable="true">
			2013	<xs:complexType>
			2014	<xs:simpleContent>
			2015	<xs:extension base="utility:generic_day">
			2016	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			2017	<xs:attribute name="cde" type="xs:string" default="2897058" />
			2018	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			2019	<xs:attribute name="tier" type="xs:string" default="2" />
			2020	</xs:extension>
			2021	</xs:simpleContent>
			2022	</xs:complexType>
			2023	</xs:element>
		-+	2025	<xs:element name="month_of_chemotherapy_end" nillable="true">
			2026	<xs:complexType>
			2027	<xs:simpleContent>
			2028	<xs:extension base="utility:generic_month">
			2029	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			2030	<xs:attribute name="cde" type="xs:string" default="2897056" />
			2031	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			2032	<xs:attribute name="tier" type="xs:string" default="2" />
			2033	</xs:extension>
			2034	</xs:simpleContent>
			2035	</xs:complexType>
			2036	</xs:element>
		-+	2038	<xs:element name="year_of_chemotherapy_end" nillable="true">
			2039	<xs:complexType>
			2040	<xs:simpleContent>
			2041	<xs:extension base="utility:generic_year">
			2042	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			2043	<xs:attribute name="cde" type="xs:string" default="2897060" />
			2044	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			2045	<xs:attribute name="tier" type="xs:string" default="2" />
			2046	</xs:extension>
			2047	</xs:simpleContent>
			2048	</xs:complexType>
			2049	</xs:element>
		-+	2051	<xs:element name="days_to_chemotherapy_end">
			2052	<xs:complexType mixed="true">
			2053	<xs:simpleContent>
			2054	<xs:restriction base="utility:clinical_res_attributes">
			2055	<xs:attribute name="cde" type="xs:string" default="" />
			2056	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			2057	<xs:attribute name="tier" type="xs:string" default="1" />
			2058	</xs:restriction>
			2059	</xs:simpleContent>
			2060	</xs:complexType>
			2061	</xs:element>
		-+	2063	<xs:element name="dose_frequency_text" nillable="true">
			2064	<xs:complexType mixed="true">
			2065	<xs:simpleContent>
			2066	<xs:restriction base="utility:clinical_res_attributes">
			2067	<xs:enumeration value="" />
			2068	<xs:enumeration value="Every hour" />
			2069	<xs:enumeration value="Five times daily" />
			2070	<xs:enumeration value="Four times daily" />
			2071	<xs:enumeration value="Three times daily" />
			2072	<xs:enumeration value="Twice daily" />
			2073	<xs:enumeration value="Every 24 hours" />
			2074	<xs:enumeration value="Every other day" />
			2075	<xs:enumeration value="Twice a week" />
			2076	<xs:enumeration value="Once weekly" />
			2077	<xs:attribute name="cde" type="xs:string" default="2179580" />
			2078	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			2079	<xs:attribute name="tier" type="xs:string" default="2" />
			2080	</xs:restriction>
			2081	</xs:simpleContent>
			2082	</xs:complexType>
			2083	</xs:element>
		-+	2085	<xs:element name="agent_total_dose_count" nillable="true">
			2086	<xs:complexType>
			2087	<xs:simpleContent>
			2088	<xs:extension base="xs:decimal">
			2089	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			2090	<xs:attribute name="cde" type="xs:string" default="2180805" />
			2091	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			2092	<xs:attribute name="tier" type="xs:string" default="2" />
			2093	</xs:extension>
			2094	</xs:simpleContent>
			2095	</xs:complexType>
			2096	</xs:element>
		-+	2098	<xs:element name="additional_treatment_completion_success_outcome_type" nillable="true">
			2099	<xs:complexType mixed="true">
			2100	<xs:simpleContent>
			2101	<xs:restriction base="utility:clinical_res_attributes">
			2102	<xs:enumeration value="" />
			2103	<xs:enumeration value="Progressive Disease" />
			2104	<xs:enumeration value="Stable Disease" />
			2105	<xs:enumeration value="Partial Response" />
			2106	<xs:enumeration value="Complete Response" />
			2107	<xs:attribute name="cde" type="xs:string" default="3033278" />
			2108	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			2109	<xs:attribute name="tier" type="xs:string" default="1" />
			2110	</xs:restriction>
			2111	</xs:simpleContent>
			2112	</xs:complexType>
			2113	</xs:element>

   
File: TCGA_BCR.CESC_Clinical_FollowUp_v2.0.xsd  

1	<?xml version="1.0" encoding="utf-8" ?>	+-
3	<xs:schema elementFormDefault="qualified" version="2.5.0"	+-
4	xmlns:xs="http://www.w3.org/2001/XMLSchema"
5	xmlns:shared="http://tcga.nci/bcr/xml/clinical/shared/2.5"
6	xmlns:utility="http://tcga.nci/bcr/xml/utility/2.5"
7	xmlns:admin="http://tcga.nci/bcr/xml/administration/2.5"
8	xmlns:rad="http://tcga.nci/bcr/xml/clinical/radiation/2.5"
9	xmlns:cesc_shared="http://tcga.nci/bcr/xml/clinical/cesc/shared/2.5"
10	xmlns="http://tcga.nci/bcr/xml/clinical/cesc/followup/2.5/2.0"
11	targetNamespace="http://tcga.nci/bcr/xml/clinical/cesc/followup/2.5/2.0"
12	xmlns:jaxb="http://java.sun.com/xml/ns/jaxb" jaxb:version="1.0" >
14	<xs:import namespace="http://tcga.nci/bcr/xml/utility/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/utility/2.5/TCGA_BCR.Utility.xsd" />	+-
15	<xs:import namespace="http://tcga.nci/bcr/xml/administration/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/administration/2.5/TCGA_BCR.Administration.xsd" />
16	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/radiation/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/radiation/2.5/TCGA_BCR.Radiation.xsd" />
17	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/shared/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/shared/2.5/TCGA_BCR.Shared_Clinical_Elements.xsd" />
18	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/cesc/shared/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/cesc/shared/2.5/TCGA_BCR.CESC_Clinical_Shared_Datatypes.xsd" />
19	<xs:annotation>
20	<xs:appinfo>
21	<jaxb:globalBindings generateIsSetMethod="true" />
22	<jaxb:schemaBindings>
23	<jaxb:package name="nci.tcga.bcr.xml.jaxb.clinical.cesc" />
24	</jaxb:schemaBindings>
25	</xs:appinfo>
26	</xs:annotation>
27	<xs:annotation>
28	<xs:documentation xml:lang="en">Schema to define the elements of the TCGA Clinical Data Follow-up Form within the CESC study.</xs:documentation>
29	</xs:annotation>
30	<xs:element name="follow_up_v2.0">
31	<xs:complexType>
32	<xs:sequence>
33	<xs:element ref="shared:bcr_patient_barcode" />
34	<xs:element ref="shared:bcr_patient_uuid" />
36	<xs:element ref="shared:followup_case_report_form_submission_reason">	+-
37	<xs:annotation>
38	<xs:documentation xml:lang="en">
39	NEW question that was added on the TCGA Clinical Data Follow-up (starting with v2.0) Form within the CESC study.
40	</xs:documentation>
41	</xs:annotation>
42	</xs:element>
43	<xs:element ref="shared:radiation_therapy" />
44	<xs:element ref="shared:targeted_molecular_therapy" />
45	<xs:element ref="shared:vital_status" />
46	<xs:choice>
47	<xs:sequence>
48	<xs:element ref="shared:day_of_last_followup" />
49	<xs:element ref="shared:month_of_last_followup" />
50	<xs:element ref="shared:year_of_last_followup" />
51	</xs:sequence>
52	<xs:element ref="shared:days_to_last_followup" />
53	</xs:choice>
54	<xs:choice>
55	<xs:sequence>
56	<xs:element ref="shared:day_of_death" />
57	<xs:element ref="shared:month_of_death" />
58	<xs:element ref="shared:year_of_death" />
59	</xs:sequence>
60	<xs:element ref="shared:days_to_birth" />
61	</xs:choice>
62	<xs:element ref="shared:person_neoplasm_cancer_status" />
63	<xs:element ref="cesc_shared:patient_death_reason" />
64	<xs:element ref="cesc_shared:death_cause_text" />
65	<xs:element ref="shared:eastern_cancer_oncology_group" />
66	<xs:element ref="shared:performance_status_scale_timing" />
67	<xs:element ref="cesc_shared:performance_status_assessment_timepoint_category_other_text" />
68	<xs:choice>
69	<xs:sequence>
70	<xs:element ref="shared:day_of_performance_status_follow_up_score" />
71	<xs:element ref="shared:month_of_performance_status_follow_up_score" />
72	<xs:element ref="shared:year_of_performance_status_follow_up_score" />
73	</xs:sequence>
74	<xs:element ref="cesc_shared:days_to_performance_status_follow_up_score" />
75	</xs:choice>
76	<xs:element ref="cesc_shared:primary_therapy_outcome_success" />
77	<xs:element ref="cesc_shared:additional_treatment_completion_success_outcome" />
78	<xs:element ref="cesc_shared:adjuvant_rad_therapy_prior_admin" />
79	<xs:element ref="cesc_shared:radiation_therapy_not_administered_reason" />
80	<xs:element ref="cesc_shared:radiation_therapy_not_administered_specify" />
81	<xs:element ref="cesc_shared:brachytherapy_method_type" />
82	<xs:element ref="cesc_shared:brachytherapy_method_other_specify_text" />
83	<xs:choice>
84	<xs:sequence>
85	<xs:element ref="cesc_shared:day_of_brachytherapy_begin_occurrence" />
86	<xs:element ref="cesc_shared:month_of_brachytherapy_begin_occurrence" />
87	<xs:element ref="cesc_shared:year_of_brachytherapy_begin_occurrence" />
88	</xs:sequence>
89	<xs:element ref="cesc_shared:days_to_brachytherapy_begin_occurrence" />
90	</xs:choice>
91	<xs:choice>
92	<xs:sequence>
93	<xs:element ref="cesc_shared:day_of_brachytherapy_end_occurrence" />
94	<xs:element ref="cesc_shared:month_of_brachytherapy_end_occurrence" />
95	<xs:element ref="cesc_shared:year_of_brachytherapy_end_occurrence" />
96	</xs:sequence>
97	<xs:element ref="cesc_shared:days_to_brachytherapy_end_occurrence" />
98	</xs:choice>
99	<xs:element ref="cesc_shared:brachytherapy_first_reference_point_administered_total_dose" />
100	<xs:element ref="cesc_shared:brachytherapy_administered_status" />
101	<xs:element ref="cesc_shared:rt_administered_type" />
102	<xs:element ref="rad:radiation_type_notes" />
103	<xs:element ref="radiation_supplemental" />
104	<xs:element ref="cesc_shared:chemotherapy_regimen_types" />
105	<xs:element ref="cesc_shared:other_chemotherapy_agent_administration_specify" />
106	<xs:choice>
107	<xs:sequence>
108	<xs:element ref="cesc_shared:day_of_chemotherapy_start" />
109	<xs:element ref="cesc_shared:month_of_chemotherapy_start" />
110	<xs:element ref="cesc_shared:year_of_chemotherapy_start" />
111	</xs:sequence>
112	<xs:element ref="cesc_shared:days_to_chemotherapy_start" />
113	</xs:choice>
114	<xs:choice>
115	<xs:sequence>
116	<xs:element ref="cesc_shared:day_of_chemotherapy_end" />
117	<xs:element ref="cesc_shared:month_of_chemotherapy_end" />
118	<xs:element ref="cesc_shared:year_of_chemotherapy_end" />
119	</xs:sequence>
120	<xs:element ref="cesc_shared:days_to_chemotherapy_end" />
121	</xs:choice>
123	<xs:element ref="cesc_shared:concurrent_chemotherapy_dose" />	+-
124	<xs:element ref="cesc_shared:dose_frequency_text" />
125	<xs:element ref="cesc_shared:agent_total_dose_count" />
127	<xs:element ref="shared:new_tumor_event_after_initial_treatment" />	+-
128	<xs:choice>
129	<xs:sequence>
130	<xs:element ref="shared:day_of_new_tumor_event_after_initial_treatment" />
131	<xs:element ref="shared:month_of_new_tumor_event_after_initial_treatment" />
132	<xs:element ref="shared:year_of_new_tumor_event_after_initial_treatment" />
133	</xs:sequence>
134	<xs:element ref="shared:days_to_new_tumor_event_after_initial_treatment" />
135	</xs:choice>
136	<xs:element ref="shared:new_neoplasm_event_type" />
137	<xs:element ref="cesc_shared:new_neoplasm_event_occurrence_anatomic_site" />
138	<xs:element ref="cesc_shared:new_neoplasm_occurrence_anatomic_site_text" />
139	<xs:element ref="cesc_shared:new_neoplasm_event_post_initial_therapy_diagnosis_method_type" />
140	<xs:element ref="cesc_shared:new_neoplasm_event_post_initial_therapy_diagnosis_method_text" />
141	<xs:choice>
142	<xs:sequence>
143	<xs:element ref="shared:day_of_additional_surgery_metastatic_procedure" />
144	<xs:element ref="shared:month_of_additional_surgery_metastatic_procedure" />
145	<xs:element ref="shared:year_of_additional_surgery_metastatic_procedure" />
146	</xs:sequence>
148	<xs:element ref="shared:days_to_additional_surgery_metastatic_procedure" />	+-
149	</xs:choice>
150	<xs:element ref="shared:residual_disease_post_new_tumor_event_margin_status" />
151	<xs:element ref="shared:additional_radiation_therapy" />
152	<xs:element ref="shared:additional_pharmaceutical_therapy" />
154	<xs:choice>	+-
155	<xs:annotation>
156	<xs:documentation>
157	Date the interviewer originally completed the corresponding TCGA Clinical Data Form.
158	If modifications are made after the form is marked complete, this date should not change.
159	</xs:documentation>
160	</xs:annotation>
161	<xs:sequence>
162	<xs:element ref="shared:day_of_form_completion" />
163	<xs:element ref="shared:month_of_form_completion" />
164	<xs:element ref="shared:year_of_form_completion" />
165	</xs:sequence>
166	<xs:element ref="shared:days_to_form_completion" />
167	</xs:choice>
168	</xs:sequence>
169	<xs:attribute name="version" type="xs:string" default="2.0" use="optional"/>
170	</xs:complexType>
171	</xs:element>
173	<xs:element name="radiation_supplemental">	+-
174	<xs:complexType>
175	<xs:sequence>
176	<xs:choice>
177	<xs:sequence>
178	<xs:element ref="rad:day_of_radiation_therapy_start" />
179	<xs:element ref="rad:month_of_radiation_therapy_start" />
180	<xs:element ref="rad:year_of_radiation_therapy_start" />
181	</xs:sequence>
183	<xs:element ref="rad:days_to_radiation_therapy_start" />	+-
184	</xs:choice>
186	<xs:choice>	+-
187	<xs:sequence>
188	<xs:element ref="rad:day_of_radiation_therapy_end" />
189	<xs:element ref="rad:month_of_radiation_therapy_end" />
190	<xs:element ref="rad:year_of_radiation_therapy_end" />
191	</xs:sequence>
193	<xs:element ref="rad:days_to_radiation_therapy_end" />	+-
194	</xs:choice>
198	<xs:element ref="cesc_shared:rt_pelvis_administered_total_dose" />	+-
199	<xs:element ref="cesc_shared:external_beam_radiation_therapy_administered_paraaortic_region_lymph_node_dose" />
200	<xs:element ref="cesc_shared:external_beam_radiation_therapy_administered_status" />
201	<xs:element ref="shared:targeted_molecular_therapy" />
202	<xs:element ref="cesc_shared:chemotherapy_negation_radiation_therapy_concurrent_not_administered_reason" />
203	<xs:element ref="cesc_shared:chemotherapy_negation_radiation_therapy_concurrent_administered_text" />
204	</xs:sequence>
205	</xs:complexType>
206	</xs:element>
209	</xs:schema>	+-

   
File: TCGA_BCR.CESC_Clinical_Shared_Datatypes.xsd  

1	<?xml version="1.0" encoding="utf-8" ?>	+-
4	<xs:schema elementFormDefault="qualified" version="2.5.0"	+-
5	xmlns:xs="http://www.w3.org/2001/XMLSchema"
6	xmlns:utility="http://tcga.nci/bcr/xml/utility/2.5"
7	xmlns="http://tcga.nci/bcr/xml/clinical/cesc/shared/2.5"
8	targetNamespace="http://tcga.nci/bcr/xml/clinical/cesc/shared/2.5">
10	<xs:import namespace="http://tcga.nci/bcr/xml/utility/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/utility/2.5/TCGA_BCR.Utility.xsd" />	+-
12	<xs:element name="patient_death_reason" nillable="true">	+-
13	<xs:complexType mixed="true">
14	<xs:simpleContent>
15	<xs:restriction base="utility:clinical_res_attributes">
16	<xs:enumeration value="" />
17	<xs:enumeration value="Cervical Cancer" />
18	<xs:enumeration value="Other, specify" />
19	<xs:attribute name="cde" type="xs:string" default="2554674" />
20	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
21	<xs:attribute name="tier" type="xs:string" default="2" />
22	</xs:restriction>
23	</xs:simpleContent>
24	</xs:complexType>
25	</xs:element>
27	<xs:element name="death_cause_text" nillable="true">	+-
28	<xs:complexType>
29	<xs:simpleContent>
30	<xs:extension base="xs:string">
31	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
32	<xs:attribute name="cde" type="xs:string" default="2004150" />
33	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
34	<xs:attribute name="tier" type="xs:string" default="2" />
35	</xs:extension>
36	</xs:simpleContent>
37	</xs:complexType>
38	</xs:element>
40	<xs:element name="performance_status_assessment_timepoint_category_other_text" nillable="true">	+-
41	<xs:complexType>
42	<xs:simpleContent>
43	<xs:extension base="xs:string">
44	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
45	<xs:attribute name="cde" type="xs:string" default="3151756" />
46	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
47	<xs:attribute name="tier" type="xs:string" default="2" />
48	</xs:extension>
49	</xs:simpleContent>
50	</xs:complexType>
51	</xs:element>
53	<xs:element name="days_to_performance_status_follow_up_score">	+-
54	<xs:complexType mixed="true">
55	<xs:simpleContent>
56	<xs:restriction base="utility:clinical_res_attributes">
57	<xs:attribute name="cde" type="xs:string" default="" />
58	<xs:attribute name="xsd_ver" type="xs:string" default="2.4" />
59	<xs:attribute name="tier" type="xs:string" default="1" />
60	</xs:restriction>
61	</xs:simpleContent>
62	</xs:complexType>
63	</xs:element>
65	<xs:element name="primary_therapy_outcome_success" nillable="true">	+-
66	<xs:complexType mixed="true">
67	<xs:simpleContent>
68	<xs:restriction base="utility:clinical_res_attributes">
69	<xs:enumeration value="" />
70	<xs:enumeration value="Progressive Disease" />
71	<xs:enumeration value="Stable Disease" />
72	<xs:enumeration value="Partial Response" />
73	<xs:enumeration value="Complete Remission/Response" />
74	<xs:enumeration value="Not Applicable" />
75	<xs:attribute name="cde" type="xs:string" default="2786727" />
76	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
77	<xs:attribute name="tier" type="xs:string" default="1" />
78	</xs:restriction>
79	</xs:simpleContent>
80	</xs:complexType>
81	</xs:element>
83	<xs:element name="additional_treatment_completion_success_outcome" nillable="true">	+-
84	<xs:complexType mixed="true">
85	<xs:simpleContent>
86	<xs:restriction base="utility:clinical_res_attributes">
87	<xs:enumeration value="" />
88	<xs:enumeration value="Progressive Disease" />
89	<xs:enumeration value="Stable Disease" />
90	<xs:enumeration value="Partial Response" />
91	<xs:enumeration value="Complete Response" />
92	<xs:attribute name="cde" type="xs:string" default="3033278" />
93	<xs:attribute name="xsd_ver" type="xs:string" default="2.5" />
94	<xs:attribute name="tier" type="xs:string" default="1" />
95	</xs:restriction>
96	</xs:simpleContent>
97	</xs:complexType>
98	</xs:element>
100	<xs:element name="adjuvant_rad_therapy_prior_admin" nillable="true">	+-
101	<xs:complexType>
102	<xs:simpleContent>
103	<xs:extension base="utility:yes_or_no">
104	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
105	<xs:attribute name="cde" type="xs:string" default="2308" />
106	<xs:attribute name="xsd_ver" type="xs:string" default="2.5" />
107	<xs:attribute name="tier" type="xs:string" default="2" />
108	</xs:extension>
109	</xs:simpleContent>
110	</xs:complexType>
111	</xs:element>
113	<xs:element name="radiation_therapy_not_administered_reason" nillable="true">	+-
114	<xs:complexType mixed="true">
115	<xs:simpleContent>
116	<xs:restriction base="utility:clinical_res_attributes">
117	<xs:enumeration value="" />
118	<xs:enumeration value="Adverse event/complications" />
119	<xs:enumeration value="Scheduling problems" />
120	<xs:enumeration value="Participant refusal" />
121	<xs:enumeration value="Not done per treating physician discretion" />
122	<xs:enumeration value="Other" />
123	<xs:attribute name="cde" type="xs:string" default="2733266" />
124	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
125	<xs:attribute name="tier" type="xs:string" default="2" />
126	</xs:restriction>
127	</xs:simpleContent>
128	</xs:complexType>
129	</xs:element>
131	<xs:element name="radiation_therapy_not_administered_specify" nillable="true">	+-
132	<xs:complexType>
133	<xs:simpleContent>
134	<xs:extension base="xs:string">
135	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
136	<xs:attribute name="cde" type="xs:string" default="2733267" />
137	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
138	<xs:attribute name="tier" type="xs:string" default="2" />
139	</xs:extension>
140	</xs:simpleContent>
141	</xs:complexType>
142	</xs:element>
144	<xs:element name="brachytherapy_method_type" nillable="true">	+-
145	<xs:complexType mixed="true">
146	<xs:simpleContent>
147	<xs:restriction base="utility:clinical_res_attributes">
148	<xs:enumeration value="" />
149	<xs:enumeration value="LDR" />
150	<xs:enumeration value="HDR" />
151	<xs:enumeration value="Other" />
152	<xs:attribute name="cde" type="xs:string" default="2966127" />
153	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
154	<xs:attribute name="tier" type="xs:string" default="2" />
155	</xs:restriction>
156	</xs:simpleContent>
157	</xs:complexType>
158	</xs:element>
160	<xs:element name="brachytherapy_method_other_specify_text" nillable="true">	+-
161	<xs:complexType>
162	<xs:simpleContent>
163	<xs:extension base="xs:string">
164	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
165	<xs:attribute name="cde" type="xs:string" default="3150976" />
166	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
167	<xs:attribute name="tier" type="xs:string" default="2" />
168	</xs:extension>
169	</xs:simpleContent>
170	</xs:complexType>
171	</xs:element>
173	<xs:element name="day_of_brachytherapy_begin_occurrence" nillable="true">	+-
174	<xs:complexType>
175	<xs:simpleContent>
176	<xs:extension base="utility:generic_day">
177	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
178	<xs:attribute name="cde" type="xs:string" default="3150980" />
179	<xs:attribute name="xsd_ver" type="xs:string" default="2.4" />
180	<xs:attribute name="tier" type="xs:string" default="2" />
181	</xs:extension>
182	</xs:simpleContent>
183	</xs:complexType>
184	</xs:element>
186	<xs:element name="month_of_brachytherapy_begin_occurrence" nillable="true">	+-
187	<xs:complexType>
188	<xs:simpleContent>
189	<xs:extension base="utility:generic_month">
190	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
191	<xs:attribute name="cde" type="xs:string" default="3150979" />
192	<xs:attribute name="xsd_ver" type="xs:string" default="2.4" />
193	<xs:attribute name="tier" type="xs:string" default="2" />
194	</xs:extension>
195	</xs:simpleContent>
196	</xs:complexType>
197	</xs:element>
199	<xs:element name="year_of_brachytherapy_begin_occurrence" nillable="true">	+-
200	<xs:complexType>
201	<xs:simpleContent>
202	<xs:extension base="utility:generic_year">
203	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
204	<xs:attribute name="cde" type="xs:string" default="3150981" />
205	<xs:attribute name="xsd_ver" type="xs:string" default="2.4" />
206	<xs:attribute name="tier" type="xs:string" default="2" />
207	</xs:extension>
208	</xs:simpleContent>
209	</xs:complexType>
210	</xs:element>
212	<xs:element name="days_to_brachytherapy_begin_occurrence">	+-
213	<xs:complexType mixed="true">
214	<xs:simpleContent>
215	<xs:restriction base="utility:clinical_res_attributes">
216	<xs:attribute name="cde" type="xs:string" default="" />
217	<xs:attribute name="xsd_ver" type="xs:string" default="2.4" />
218	<xs:attribute name="tier" type="xs:string" default="1" />
219	</xs:restriction>
220	</xs:simpleContent>
221	</xs:complexType>
222	</xs:element>
224	<xs:element name="day_of_brachytherapy_end_occurrence" nillable="true">	+-
225	<xs:complexType>
226	<xs:simpleContent>
227	<xs:extension base="utility:generic_day">
228	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
229	<xs:attribute name="cde" type="xs:string" default="3151011" />
230	<xs:attribute name="xsd_ver" type="xs:string" default="2.4" />
231	<xs:attribute name="tier" type="xs:string" default="2" />
232	</xs:extension>
233	</xs:simpleContent>
234	</xs:complexType>
235	</xs:element>
237	<xs:element name="month_of_brachytherapy_end_occurrence" nillable="true">	+-
238	<xs:complexType>
239	<xs:simpleContent>
240	<xs:extension base="utility:generic_month">
241	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
242	<xs:attribute name="cde" type="xs:string" default="3151002" />
243	<xs:attribute name="xsd_ver" type="xs:string" default="2.4" />
244	<xs:attribute name="tier" type="xs:string" default="2" />
245	</xs:extension>
246	</xs:simpleContent>
247	</xs:complexType>
248	</xs:element>
250	<xs:element name="year_of_brachytherapy_end_occurrence" nillable="true">	+-
251	<xs:complexType>
252	<xs:simpleContent>
253	<xs:extension base="utility:generic_year">
254	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
255	<xs:attribute name="cde" type="xs:string" default="3151068" />
256	<xs:attribute name="xsd_ver" type="xs:string" default="2.4" />
257	<xs:attribute name="tier" type="xs:string" default="2" />
258	</xs:extension>
259	</xs:simpleContent>
260	</xs:complexType>
261	</xs:element>
263	<xs:element name="days_to_brachytherapy_end_occurrence">	+-
264	<xs:complexType mixed="true">
265	<xs:simpleContent>
266	<xs:restriction base="utility:clinical_res_attributes">
267	<xs:attribute name="cde" type="xs:string" default="" />
268	<xs:attribute name="xsd_ver" type="xs:string" default="2.4" />
269	<xs:attribute name="tier" type="xs:string" default="1" />
270	</xs:restriction>
271	</xs:simpleContent>
272	</xs:complexType>
273	</xs:element>
275	<xs:element name="brachytherapy_first_reference_point_administered_total_dose" nillable="true">	+-
276	<xs:complexType>
277	<xs:simpleContent>
278	<xs:extension base="utility:number_or_null">
279	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
280	<xs:attribute name="cde" type="xs:string" default="3151100" />
281	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
282	<xs:attribute name="tier" type="xs:string" default="2" />
283	<xs:attribute name="units" type="xs:string" fixed="cGy"/>
284	</xs:extension>
285	</xs:simpleContent>
286	</xs:complexType>
287	</xs:element>
289	<xs:element name="brachytherapy_administered_status" nillable="true">	+-
290	<xs:complexType mixed="true">
291	<xs:simpleContent>
292	<xs:restriction base="utility:clinical_res_attributes">
293	<xs:enumeration value="" />
294	<xs:enumeration value="Completed as planned" />
295	<xs:enumeration value="Treatment not completed" />
296	<xs:attribute name="cde" type="xs:string" default="3151103" />
297	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
298	<xs:attribute name="tier" type="xs:string" default="2" />
299	</xs:restriction>
300	</xs:simpleContent>
301	</xs:complexType>
302	</xs:element>
304	<xs:element name="rt_administered_type" nillable="true">	+-
305	<xs:complexType mixed="true">
306	<xs:simpleContent>
307	<xs:restriction base="utility:clinical_res_attributes">
308	<xs:enumeration value="" />
309	<xs:enumeration value="3D conformal" />
310	<xs:enumeration value="IMRT" />
311	<xs:enumeration value="External beam radiation" />
312	<xs:enumeration value="Other" />
313	<xs:attribute name="cde" type="xs:string" default="61468" />
314	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
315	<xs:attribute name="tier" type="xs:string" default="2" />
316	</xs:restriction>
317	</xs:simpleContent>
318	</xs:complexType>
319	</xs:element>
321	<xs:element name="rt_pelvis_administered_total_dose" nillable="true">	+-
322	<xs:complexType>
323	<xs:simpleContent>
324	<xs:extension base="utility:number_or_null">
325	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
326	<xs:attribute name="cde" type="xs:string" default="3006" />
327	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
328	<xs:attribute name="tier" type="xs:string" default="2" />
329	<xs:attribute name="units" type="xs:string" fixed="cGy"/>
330	</xs:extension>
331	</xs:simpleContent>
332	</xs:complexType>
333	</xs:element>
335	<xs:element name="external_beam_radiation_therapy_administered_paraaortic_region_lymph_node_dose" nillable="true">	+-
336	<xs:complexType>
337	<xs:simpleContent>
338	<xs:extension base="utility:number_or_null">
339	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
340	<xs:attribute name="cde" type="xs:string" default="3151106" />
341	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
342	<xs:attribute name="tier" type="xs:string" default="2" />
343	<xs:attribute name="units" type="xs:string" fixed="cGy"/>
344	</xs:extension>
345	</xs:simpleContent>
346	</xs:complexType>
347	</xs:element>
349	<xs:element name="external_beam_radiation_therapy_administered_status" nillable="true">	+-
350	<xs:complexType mixed="true">
351	<xs:simpleContent>
352	<xs:restriction base="utility:clinical_res_attributes">
353	<xs:enumeration value="" />
354	<xs:enumeration value="Treatment not completed" />
355	<xs:enumeration value="Completed as Planned" />
356	<xs:attribute name="cde" type="xs:string" default="3151107" />
357	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
358	<xs:attribute name="tier" type="xs:string" default="2" />
359	</xs:restriction>
360	</xs:simpleContent>
361	</xs:complexType>
362	</xs:element>
364	<xs:element name="chemotherapy_negation_radiation_therapy_concurrent_not_administered_reason" nillable="true">	+-
365	<xs:complexType mixed="true">
366	<xs:simpleContent>
367	<xs:restriction base="utility:clinical_res_attributes">
368	<xs:enumeration value="" />
369	<xs:enumeration value="Adverse event/ complications" />
370	<xs:enumeration value="Scheduling problems" />
371	<xs:enumeration value="Participant refusal" />
372	<xs:enumeration value="Not done per treating physicians discretion" />
373	<xs:enumeration value="Other" />
374	<xs:attribute name="cde" type="xs:string" default="3151120" />
375	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
376	<xs:attribute name="tier" type="xs:string" default="2" />
377	</xs:restriction>
378	</xs:simpleContent>
379	</xs:complexType>
380	</xs:element>
382	<xs:element name="chemotherapy_negation_radiation_therapy_concurrent_administered_text" nillable="true">	+-
383	<xs:complexType>
384	<xs:simpleContent>
385	<xs:extension base="xs:string">
386	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
387	<xs:attribute name="cde" type="xs:string" default="3151824" />
388	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
389	<xs:attribute name="tier" type="xs:string" default="2" />
390	</xs:extension>
391	</xs:simpleContent>
392	</xs:complexType>
393	</xs:element>
395	<xs:element name="chemotherapy_regimen_types">	+-
396	<xs:complexType>
397	<xs:sequence >
398	<xs:element ref="chemotherapy_regimen_type" minOccurs="0" maxOccurs="unbounded" />
399	</xs:sequence>
400	</xs:complexType>
401	</xs:element>
403	<xs:element name="chemotherapy_regimen_type" nillable="true">	+-
404	<xs:complexType mixed="true">
405	<xs:simpleContent>
406	<xs:restriction base="utility:clinical_res_attributes">
407	<xs:enumeration value="" />
408	<xs:enumeration value="Carboplatin" />
409	<xs:enumeration value="Cisplatin" />
410	<xs:enumeration value="Other" />
411	<xs:attribute name="cde" type="xs:string" default="2007212" />
412	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
413	<xs:attribute name="tier" type="xs:string" default="2" />
414	</xs:restriction>
415	</xs:simpleContent>
416	</xs:complexType>
417	</xs:element>
419	<xs:element name="other_chemotherapy_agent_administration_specify" nillable="true">	+-
420	<xs:complexType>
421	<xs:simpleContent>
422	<xs:extension base="xs:string">
423	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
424	<xs:attribute name="cde" type="xs:string" default="2426129" />
425	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
426	<xs:attribute name="tier" type="xs:string" default="2" />
427	</xs:extension>
428	</xs:simpleContent>
429	</xs:complexType>
430	</xs:element>
432	<xs:element name="day_of_chemotherapy_start" nillable="true">	+-
433	<xs:complexType>
434	<xs:simpleContent>
435	<xs:extension base="utility:generic_day">
436	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
437	<xs:attribute name="cde" type="xs:string" default="2897052" />
438	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
439	<xs:attribute name="tier" type="xs:string" default="2" />
440	</xs:extension>
441	</xs:simpleContent>
442	</xs:complexType>
443	</xs:element>
445	<xs:element name="month_of_chemotherapy_start" nillable="true">	+-
446	<xs:complexType>
447	<xs:simpleContent>
448	<xs:extension base="utility:generic_month">
449	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
450	<xs:attribute name="cde" type="xs:string" default="2897050" />
451	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
452	<xs:attribute name="tier" type="xs:string" default="2" />
453	</xs:extension>
454	</xs:simpleContent>
455	</xs:complexType>
456	</xs:element>
458	<xs:element name="year_of_chemotherapy_start" nillable="true">	+-
459	<xs:complexType>
460	<xs:simpleContent>
461	<xs:extension base="utility:generic_year">
462	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
463	<xs:attribute name="cde" type="xs:string" default="2897054" />
464	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
465	<xs:attribute name="tier" type="xs:string" default="2" />
466	</xs:extension>
467	</xs:simpleContent>
468	</xs:complexType>
469	</xs:element>
471	<xs:element name="days_to_chemotherapy_start">	+-
472	<xs:complexType mixed="true">
473	<xs:simpleContent>
474	<xs:restriction base="utility:clinical_res_attributes">
475	<xs:attribute name="cde" type="xs:string" default="" />
476	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
477	<xs:attribute name="tier" type="xs:string" default="1" />
478	</xs:restriction>
479	</xs:simpleContent>
480	</xs:complexType>
481	</xs:element>
483	<xs:element name="day_of_chemotherapy_end" nillable="true">	+-
484	<xs:complexType>
485	<xs:simpleContent>
486	<xs:extension base="utility:generic_day">
487	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
488	<xs:attribute name="cde" type="xs:string" default="2897058" />
489	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
490	<xs:attribute name="tier" type="xs:string" default="2" />
491	</xs:extension>
492	</xs:simpleContent>
493	</xs:complexType>
494	</xs:element>
496	<xs:element name="month_of_chemotherapy_end" nillable="true">	+-
497	<xs:complexType>
498	<xs:simpleContent>
499	<xs:extension base="utility:generic_month">
500	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
501	<xs:attribute name="cde" type="xs:string" default="2897056" />
502	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
503	<xs:attribute name="tier" type="xs:string" default="2" />
504	</xs:extension>
505	</xs:simpleContent>
506	</xs:complexType>
507	</xs:element>
509	<xs:element name="year_of_chemotherapy_end" nillable="true">	+-
510	<xs:complexType>
511	<xs:simpleContent>
512	<xs:extension base="utility:generic_year">
513	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
514	<xs:attribute name="cde" type="xs:string" default="2897060" />
515	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
516	<xs:attribute name="tier" type="xs:string" default="2" />
517	</xs:extension>
518	</xs:simpleContent>
519	</xs:complexType>
520	</xs:element>
522	<xs:element name="days_to_chemotherapy_end">	+-
523	<xs:complexType mixed="true">
524	<xs:simpleContent>
525	<xs:restriction base="utility:clinical_res_attributes">
526	<xs:attribute name="cde" type="xs:string" default="" />
527	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
528	<xs:attribute name="tier" type="xs:string" default="1" />
529	</xs:restriction>
530	</xs:simpleContent>
531	</xs:complexType>
532	</xs:element>
536	<xs:element name="concurrent_chemotherapy_dose" nillable="true">	+-
537	<xs:complexType>
538	<xs:simpleContent>
539	<xs:extension base="xs:string">
540	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
541	<xs:attribute name="cde" type="xs:string" default="3166172" />
542	<xs:attribute name="xsd_ver" type="xs:string" default="2.5" />
543	<xs:attribute name="tier" type="xs:string" default="2" />
544	</xs:extension>
545	</xs:simpleContent>
546	</xs:complexType>
547	</xs:element>
551	<xs:element name="dose_frequency_text" nillable="true">	+-
552	<xs:complexType mixed="true">
553	<xs:simpleContent>
554	<xs:restriction base="utility:clinical_res_attributes">
555	<xs:enumeration value="" />
556	<xs:enumeration value="Every hour" />
557	<xs:enumeration value="Five times daily" />
558	<xs:enumeration value="Four times daily" />
559	<xs:enumeration value="Three times daily" />
560	<xs:enumeration value="Twice daily" />
561	<xs:enumeration value="Every 24 hours" />
562	<xs:enumeration value="Every other day" />
563	<xs:enumeration value="Twice a week" />
564	<xs:enumeration value="Once weekly" />
565	<xs:attribute name="cde" type="xs:string" default="2179580" />
566	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
567	<xs:attribute name="tier" type="xs:string" default="2" />
568	</xs:restriction>
569	</xs:simpleContent>
570	</xs:complexType>
571	</xs:element>
573	<xs:element name="agent_total_dose_count" nillable="true">	+-
574	<xs:complexType>
575	<xs:simpleContent>
576	<xs:extension base="utility:number_or_null">
577	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
578	<xs:attribute name="cde" type="xs:string" default="2180805" />
579	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
580	<xs:attribute name="tier" type="xs:string" default="2" />
581	</xs:extension>
582	</xs:simpleContent>
583	</xs:complexType>
584	</xs:element>
586	<xs:element name="new_neoplasm_event_occurrence_anatomic_site" nillable="true">	+-
587	<xs:complexType mixed="true">
588	<xs:simpleContent>
589	<xs:restriction base="utility:clinical_res_attributes">
590	<xs:enumeration value="" />
591	<xs:enumeration value="Cervix" />
592	<xs:enumeration value="Head &amp; Neck" />
593	<xs:enumeration value="Lung" />
594	<xs:enumeration value="Vulva" />
595	<xs:enumeration value="Anus" />
596	<xs:enumeration value="Other, specify" />
597	<xs:attribute name="cde" type="xs:string" default="3108271" />
598	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
599	<xs:attribute name="tier" type="xs:string" default="2" />
600	</xs:restriction>
601	</xs:simpleContent>
602	</xs:complexType>
603	</xs:element>
605	<xs:element name="new_neoplasm_occurrence_anatomic_site_text" nillable="true">	+-
606	<xs:complexType>
607	<xs:simpleContent>
608	<xs:extension base="xs:string">
609	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
610	<xs:attribute name="cde" type="xs:string" default="3128033" />
611	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
612	<xs:attribute name="tier" type="xs:string" default="2" />
613	</xs:extension>
614	</xs:simpleContent>
615	</xs:complexType>
616	</xs:element>
618	<xs:element name="new_neoplasm_event_post_initial_therapy_diagnosis_method_type" nillable="true">	+-
619	<xs:complexType mixed="true">
620	<xs:simpleContent>
621	<xs:restriction base="utility:clinical_res_attributes">
622	<xs:enumeration value="" />
623	<xs:enumeration value="Tumor Resection" />
624	<xs:enumeration value="Cytology" />
625	<xs:enumeration value="Not Applicable" />
626	<xs:enumeration value="Other, specify" />
627	<xs:attribute name="cde" type="xs:string" default="3151113" />
628	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
629	<xs:attribute name="tier" type="xs:string" default="2" />
630	</xs:restriction>
631	</xs:simpleContent>
632	</xs:complexType>
633	</xs:element>
635	<xs:element name="new_neoplasm_event_post_initial_therapy_diagnosis_method_text" nillable="true">	+-
636	<xs:complexType>
637	<xs:simpleContent>
638	<xs:extension base="xs:string">
639	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
640	<xs:attribute name="cde" type="xs:string" default="3151116" />
641	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
642	<xs:attribute name="tier" type="xs:string" default="2" />
643	</xs:extension>
644	</xs:simpleContent>
645	</xs:complexType>
646	</xs:element>
648	</xs:schema>	+-

   
File: TCGA_BCR.COAD_Clinical.xsd  

4	<xs:schema elementFormDefault="qualified" version="2.5.0"	<>	4	<xs:schema elementFormDefault="qualified" version="2.4.4"
6	xmlns:utility="http://tcga.nci/bcr/xml/utility/2.5"	<>	6	xmlns:utility="http://tcga.nci/bcr/xml/utility/2.4"
7	xmlns:admin="http://tcga.nci/bcr/xml/administration/2.5"		7	xmlns:admin="http://tcga.nci/bcr/xml/administration/2.4"
8	xmlns:shared="http://tcga.nci/bcr/xml/clinical/shared/2.5"		8	xmlns:shared="http://tcga.nci/bcr/xml/clinical/shared/2.4"
9	xmlns:coad_read_shared="http://tcga.nci/bcr/xml/clinical/shared/coad_read/2.5"
10	xmlns:rad="http://tcga.nci/bcr/xml/clinical/radiation/2.5"		9	xmlns:rad="http://tcga.nci/bcr/xml/clinical/radiation/2.4"
11	xmlns:rx="http://tcga.nci/bcr/xml/clinical/pharmaceutical/2.5"		10	xmlns:rx="http://tcga.nci/bcr/xml/clinical/pharmaceutical/2.4"
12	xmlns:cqcf="http://tcga.nci/bcr/xml/clinical/cqcf/2.5"
13	xmlns:follow_up_v1.0="http://tcga.nci/bcr/xml/clinical/coad/followup/2.5/1.0"
14	xmlns="http://tcga.nci/bcr/xml/clinical/coad/2.5"		11	xmlns="http://tcga.nci/bcr/xml/clinical/coad/2.4"
15	targetNamespace="http://tcga.nci/bcr/xml/clinical/coad/2.5"		12	targetNamespace="http://tcga.nci/bcr/xml/clinical/coad/2.4"
31	<xs:import namespace="http://tcga.nci/bcr/xml/utility/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/utility/2.5/TCGA_BCR.Utility.xsd" />	<>	28	<xs:import namespace="http://tcga.nci/bcr/xml/utility/2.4" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/utility/2.4/TCGA_BCR.Utility.xsd" />
32	<xs:import namespace="http://tcga.nci/bcr/xml/administration/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/administration/2.5/TCGA_BCR.Administration.xsd" />		29	<xs:import namespace="http://tcga.nci/bcr/xml/administration/2.4" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/administration/2.4/TCGA_BCR.Administration.xsd" />
33	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/shared/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/shared/2.5/TCGA_BCR.Shared_Clinical_Elements.xsd" />		30	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/shared/2.4" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/shared/2.4/TCGA_BCR.Shared_Clinical_Elements.xsd" />
34	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/radiation/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/radiation/2.5/TCGA_BCR.Radiation.xsd" />		31	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/radiation/2.4" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/radiation/2.4/TCGA_BCR.Radiation.xsd" />
35	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/pharmaceutical/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/pharmaceutical/2.5/TCGA_BCR.Pharmaceutical.xsd" />		32	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/pharmaceutical/2.4" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/pharmaceutical/2.4/TCGA_BCR.Pharmaceutical.xsd" />
36	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/cqcf/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/cqcf/2.5/TCGA_BCR.CQCF.xsd" />
37	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/coad/followup/2.5/1.0" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/coad/followup/2.5/TCGA_BCR.COAD_Clinical_FollowUp_v1.0.xsd" />
38	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/shared/coad_read/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/shared/2.5/TCGA_BCR.Shared_Clinical_COAD_READ_Elements.xsd" />
48	<xs:attribute name="schemaVersion" type="xs:decimal" use="required" fixed="2.5"/>	<>	41	<xs:attribute name="schemaVersion" type="xs:decimal" use="required" fixed="2.4"/>
56	<xs:element ref="coad_read_shared:histological_type" />	<>	49	<xs:element ref="histological_type" />
140	<xs:element ref="shared:residual_tumor" />	+-
141	<xs:element ref="shared:anatomic_organ_subdivision" />
142	<xs:element ref="shared:primary_lymph_node_presentation_assessment" />
143	<xs:element ref="shared:lymph_node_examined_count" />
144	<xs:element ref="shared:number_of_lymphnodes_positive_by_he" />
145	<xs:element ref="shared:number_of_lymphnodes_positive_by_ihc" />
149	<xs:element ref="coad_read_shared:tumor_stage" />	<>	136	<xs:element ref="tumor_stage" />
			137	<xs:element ref="residual_tumor" />
			138	<xs:element ref="anatomic_organ_subdivision" />
			139	<xs:element ref="lymphnodes_examined" />
			140	<xs:element ref="number_of_lymphnodes_examined" />
			141	<xs:element ref="number_of_lymphnodes_positive_by_he" />
			142	<xs:element ref="number_of_lymphnodes_positive_by_ihc" />
150	<xs:element ref="coad_read_shared:primary_tumor_pathologic_spread" />		143	<xs:element ref="primary_tumor_pathologic_spread" />
151	<xs:element ref="coad_read_shared:lymphnode_pathologic_spread" />		144	<xs:element ref="lymphnode_pathologic_spread" />
152	<xs:element ref="coad_read_shared:distant_metastasis_pathologic_spread" />		145	<xs:element ref="distant_metastasis_pathologic_spread" />
153	<xs:element ref="coad_read_shared:preoperative_pretreatment_cea_level" />		146	<xs:element ref="preoperative_pretreatment_cea_level" />
154	<xs:element ref="coad_read_shared:non_nodal_tumor_deposits" />		147	<xs:element ref="non_nodal_tumor_deposits" />
155	<xs:element ref="coad_read_shared:circumferential_resection_margin" />		148	<xs:element ref="circumferential_resection_margin" />
156	<xs:element ref="shared:venous_invasion" />		149	<xs:element ref="vascular_invasion_present" />
157	<xs:element ref="shared:lymphatic_invasion" />		150	<xs:element ref="lymphatic_invasion_present" />
158	<xs:element ref="coad_read_shared:perineural_invasion_present" />		151	<xs:element ref="perineural_invasion_present" />
159	<xs:element ref="coad_read_shared:microsatellite_instability" />		152	<xs:element ref="microsatellite_instability" />
160	<xs:element ref="coad_read_shared:number_of_loci_tested" />		153	<xs:element ref="number_of_loci_tested" />
161	<xs:element ref="coad_read_shared:number_of_abnormal_loci" />		154	<xs:element ref="number_of_abnormal_loci" />
162	<xs:element ref="coad_read_shared:kras_gene_analysis_performed" />		155	<xs:element ref="kras_gene_analysis_performed" />
163	<xs:element ref="coad_read_shared:kras_mutation_found" />		156	<xs:element ref="kras_mutation_found" />
164	<xs:element ref="coad_read_shared:kras_mutation_codon" />		157	<xs:element ref="kras_mutation_codon" />
165	<xs:element ref="coad_read_shared:braf_gene_analysis_performed" />		158	<xs:element ref="braf_gene_analysis_performed" />
166	<xs:element ref="coad_read_shared:braf_gene_analysis_result" />		159	<xs:element ref="braf_gene_analysis_result" />
167	<xs:element ref="coad_read_shared:synchronous_colon_cancer_present" />		160	<xs:element ref="synchronous_colon_cancer_present" />
168	<xs:element ref="coad_read_shared:history_of_colon_polyps" />		161	<xs:element ref="history_of_colon_polyps" />
169	<xs:element ref="coad_read_shared:colon_polyps_present" />		162	<xs:element ref="colon_polyps_present" />
170	<xs:element ref="coad_read_shared:loss_expression_of_mismatch_repair_proteins_by_ihc" />		163	<xs:element ref="loss_expression_of_mismatch_repair_proteins_by_ihc" />
171	<xs:element ref="coad_read_shared:loss_expression_of_mismatch_repair_proteins_by_ihc_results" />		164	<xs:element ref="loss_expression_of_mismatch_repair_proteins_by_ihc_results" />
172	<xs:element ref="coad_read_shared:number_of_first_degree_relatives_with_cancer_diagnosis" />		165	<xs:element ref="number_of_first_degree_relatives_with_cancer_diagnosis" />
176		<>	168	</xs:sequence>
			169	</xs:complexType>
			170	</xs:element>
177	<xs:element ref="coad_read_shared:clinical_cqcf" />	<>	172	<xs:element name="lymphnodes_examined" nillable="true">
			173	<xs:complexType>
			174	<xs:simpleContent>
			175	<xs:extension base="utility:yes_or_no">
			176	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			177	<xs:attribute name="cde" type="xs:string" default="2200396" />
			178	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
			179	<xs:attribute name="tier" type="xs:string" default="1" />
			180	</xs:extension>
			181	</xs:simpleContent>
			182	</xs:complexType>
			183	</xs:element>
		<>	185	<xs:element name="number_of_abnormal_loci" nillable="true">
179	<xs:element name="follow_ups">		186	<xs:complexType mixed="true">
180	<xs:annotation>		187	<xs:simpleContent>
			188	<xs:restriction base="utility:clinical_res_attributes">
			189	<xs:attribute name="cde" type="xs:string" default="3107129" />
			190	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			191	<xs:attribute name="tier" type="xs:string" default="1" />
			192	</xs:restriction>
			193	</xs:simpleContent>
			194	</xs:complexType>
			195	</xs:element>
181	<xs:documentation>We are using namespaces and version numbers to distinguish one version of followup from another.</xs:documentation>	<>	197	<xs:element name="number_of_first_degree_relatives_with_cancer_diagnosis" nillable="true">
			198	<xs:complexType mixed="true">
			199	<xs:simpleContent>
			200	<xs:restriction base="utility:clinical_res_attributes">
			201	<xs:attribute name="cde" type="xs:string" default="3107205" />
			202	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			203	<xs:attribute name="tier" type="xs:string" default="1" />
			204	</xs:restriction>
182	</xs:annotation>		205	</xs:simpleContent>
			206	</xs:complexType>
			207	</xs:element>
		-+	209	<xs:element name="loss_expression_of_mismatch_repair_proteins_by_ihc_results">
184	<xs:sequence>	<>
185	<xs:element ref="follow_up_v1.0:follow_up_v1.0" minOccurs="0" maxOccurs="unbounded" />		211	<xs:sequence minOccurs="0" maxOccurs="unbounded">
			212	<xs:element ref="loss_expression_of_mismatch_repair_proteins_by_ihc_result" />
		<>	217	<xs:element name="loss_expression_of_mismatch_repair_proteins_by_ihc_result" nillable="true">
			218	<xs:complexType mixed="true">
			219	<xs:simpleContent>
			220	<xs:restriction base="utility:clinical_res_attributes">
			221	<xs:enumeration value="" />
			222	<xs:enumeration value="MLH1 Expressed" />
			223	<xs:enumeration value="MLH1 Not Expressed" />
			224	<xs:enumeration value="MSH2 Expressed" />
			225	<xs:enumeration value="MSH2 Not Expressed" />
			226	<xs:enumeration value="PMS2 Expressed" />
			227	<xs:enumeration value="PMS2 Not Expressed" />
			228	<xs:enumeration value="MSH6 Expressed" />
			229	<xs:enumeration value="MSH6 Not Expressed" />
			230	<xs:attribute name="cde" type="xs:string" default="3105496" />
			231	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			232	<xs:attribute name="tier" type="xs:string" default="2" />
			233	</xs:restriction>
			234	</xs:simpleContent>
			235	</xs:complexType>
190	</xs:sequence>		236	</xs:element>
		-+	238	<xs:element name="braf_gene_analysis_result" nillable="true">
			239	<xs:complexType mixed="true">
			240	<xs:simpleContent>
			241	<xs:restriction base="utility:clinical_res_attributes">
			242	<xs:enumeration value="" />
			243	<xs:enumeration value="Normal" />
			244	<xs:enumeration value="Abnormal" />
			245	<xs:attribute name="cde" type="xs:string" default="3107189" />
			246	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			247	<xs:attribute name="tier" type="xs:string" default="2" />
			248	</xs:restriction>
			249	</xs:simpleContent>
		-+	253	<xs:element name="loss_expression_of_mismatch_repair_proteins_by_ihc" nillable="true">
			254	<xs:complexType>
			255	<xs:simpleContent>
			256	<xs:extension base="utility:yes_or_no">
			257	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			258	<xs:attribute name="cde" type="xs:string" default="3123153" />
			259	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			260	<xs:attribute name="tier" type="xs:string" default="1" />
			261	</xs:extension>
			262	</xs:simpleContent>
			263	</xs:complexType>
			264	</xs:element>
		-+	266	<xs:element name="braf_gene_analysis_performed" nillable="true">
			267	<xs:complexType>
			268	<xs:simpleContent>
			269	<xs:extension base="utility:yes_or_no">
			270	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			271	<xs:attribute name="cde" type="xs:string" default="3123151" />
			272	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			273	<xs:attribute name="tier" type="xs:string" default="1" />
			274	</xs:extension>
			275	</xs:simpleContent>
			276	</xs:complexType>
			277	</xs:element>
		-+	279	<xs:element name="number_of_loci_tested" nillable="true">
			280	<xs:complexType mixed="true">
			281	<xs:simpleContent>
			282	<xs:restriction base="utility:clinical_res_attributes">
			283	<xs:attribute name="cde" type="xs:string" default="3107127" />
			284	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			285	<xs:attribute name="tier" type="xs:string" default="1" />
			286	</xs:restriction>
			287	</xs:simpleContent>
			288	</xs:complexType>
			289	</xs:element>
		-+	291	<xs:element name="kras_mutation_codon" nillable="true">
			292	<xs:complexType mixed="true">
			293	<xs:simpleContent>
			294	<xs:restriction base="utility:clinical_res_attributes">
			295	<xs:enumeration value="" />
			296	<xs:enumeration value="12" />
			297	<xs:enumeration value="13" />
			298	<xs:enumeration value="61" />
			299	<xs:attribute name="cde" type="xs:string" default="3124509" />
			300	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			301	<xs:attribute name="tier" type="xs:string" default="2" />
			302	</xs:restriction>
			303	</xs:simpleContent>
			304	</xs:complexType>
			305	</xs:element>
		-+	307	<xs:element name="kras_mutation_found" nillable="true">
			308	<xs:complexType>
			309	<xs:simpleContent>
			310	<xs:extension base="utility:yes_or_no">
			311	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			312	<xs:attribute name="cde" type="xs:string" default="2932340" />
			313	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			314	<xs:attribute name="tier" type="xs:string" default="1" />
			315	</xs:extension>
			316	</xs:simpleContent>
			317	</xs:complexType>
			318	</xs:element>
		-+	320	<xs:element name="kras_gene_analysis_performed" nillable="true">
			321	<xs:complexType>
			322	<xs:simpleContent>
			323	<xs:extension base="utility:yes_or_no">
			324	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			325	<xs:attribute name="cde" type="xs:string" default="3123147" />
			326	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			327	<xs:attribute name="tier" type="xs:string" default="1" />
			328	</xs:extension>
			329	</xs:simpleContent>
			330	</xs:complexType>
			331	</xs:element>
		-+	333	<xs:element name="number_of_lymphnodes_positive_by_he" nillable="true">
			334	<xs:complexType mixed="true">
			335	<xs:simpleContent>
			336	<xs:restriction base="utility:clinical_res_attributes">
			337	<xs:attribute name="cde" type="xs:string" default="3086388" />
			338	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
			339	<xs:attribute name="tier" type="xs:string" default="1" />
			340	</xs:restriction>
			341	</xs:simpleContent>
			342	</xs:complexType>
			343	</xs:element>
		-+	345	<xs:element name="preoperative_pretreatment_cea_level" nillable="true">
			346	<xs:complexType mixed="true">
			347	<xs:simpleContent>
			348	<xs:restriction base="utility:clinical_res_attributes">
			349	<xs:attribute name="cde" type="xs:string" default="2716510" />
			350	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
			351	<xs:attribute name="tier" type="xs:string" default="1" />
			352	</xs:restriction>
			353	</xs:simpleContent>
			354	</xs:complexType>
			355	</xs:element>
		-+	357	<xs:element name="non_nodal_tumor_deposits" nillable="true">
			358	<xs:complexType>
			359	<xs:simpleContent>
			360	<xs:extension base="utility:yes_or_no">
			361	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			362	<xs:attribute name="cde" type="xs:string" default="3107051" />
			363	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
			364	<xs:attribute name="tier" type="xs:string" default="1" />
			365	</xs:extension>
			366	</xs:simpleContent>
			367	</xs:complexType>
			368	</xs:element>
		-+	370	<xs:element name="circumferential_resection_margin" nillable="true">
			371	<xs:complexType mixed="true">
			372	<xs:simpleContent>
			373	<xs:restriction base="utility:clinical_res_attributes">
			374	<xs:attribute name="cde" type="xs:string" default="64202" />
			375	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
			376	<xs:attribute name="tier" type="xs:string" default="1" />
			377	</xs:restriction>
			378	</xs:simpleContent>
			379	</xs:complexType>
			380	</xs:element>
		-+	382	<xs:element name="vascular_invasion_present" nillable="true">
			383	<xs:complexType>
			384	<xs:simpleContent>
			385	<xs:extension base="utility:yes_or_no">
			386	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			387	<xs:attribute name="cde" type="xs:string" default="64358" />
			388	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
			389	<xs:attribute name="tier" type="xs:string" default="1" />
			390	</xs:extension>
			391	</xs:simpleContent>
			392	</xs:complexType>
			393	</xs:element>
		-+	395	<xs:element name="lymphatic_invasion_present" nillable="true">
			396	<xs:complexType>
			397	<xs:simpleContent>
			398	<xs:extension base="utility:yes_or_no">
			399	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			400	<xs:attribute name="cde" type="xs:string" default="64171" />
			401	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
			402	<xs:attribute name="tier" type="xs:string" default="1" />
			403	</xs:extension>
			404	</xs:simpleContent>
			405	</xs:complexType>
			406	</xs:element>
		-+	408	<xs:element name="perineural_invasion_present" nillable="true">
			409	<xs:complexType>
			410	<xs:simpleContent>
			411	<xs:extension base="utility:yes_or_no">
			412	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			413	<xs:attribute name="cde" type="xs:string" default="64181" />
			414	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
			415	<xs:attribute name="tier" type="xs:string" default="1" />
			416	</xs:extension>
			417	</xs:simpleContent>
			418	</xs:complexType>
			419	</xs:element>
		-+	421	<xs:element name="microsatellite_instability" nillable="true">
			422	<xs:complexType>
			423	<xs:simpleContent>
			424	<xs:extension base="utility:yes_or_no">
			425	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			426	<xs:attribute name="cde" type="xs:string" default="3123142" />
			427	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
			428	<xs:attribute name="tier" type="xs:string" default="1" />
			429	</xs:extension>
			430	</xs:simpleContent>
			431	</xs:complexType>
			432	</xs:element>
		-+	434	<xs:element name="synchronous_colon_cancer_present" nillable="true">
			435	<xs:complexType>
			436	<xs:simpleContent>
			437	<xs:extension base="utility:yes_or_no">
			438	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			439	<xs:attribute name="cde" type="xs:string" default="2185953" />
			440	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
			441	<xs:attribute name="tier" type="xs:string" default="1" />
			442	</xs:extension>
			443	</xs:simpleContent>
			444	</xs:complexType>
			445	</xs:element>
		-+	447	<xs:element name="history_of_colon_polyps" nillable="true">
			448	<xs:complexType>
			449	<xs:simpleContent>
			450	<xs:extension base="utility:yes_or_no">
			451	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			452	<xs:attribute name="cde" type="xs:string" default="3107197" />
			453	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
			454	<xs:attribute name="tier" type="xs:string" default="1" />
			455	</xs:extension>
			456	</xs:simpleContent>
			457	</xs:complexType>
			458	</xs:element>
		-+	460	<xs:element name="colon_polyps_present" nillable="true">
			461	<xs:complexType>
			462	<xs:simpleContent>
			463	<xs:extension base="utility:yes_or_no">
			464	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			465	<xs:attribute name="cde" type="xs:string" default="64184" />
			466	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
			467	<xs:attribute name="tier" type="xs:string" default="1" />
			468	</xs:extension>
			469	</xs:simpleContent>
			470	</xs:complexType>
			471	</xs:element>
		-+	474	<xs:element name="anatomic_organ_subdivision" nillable="true">
			475	<xs:complexType mixed="true">
			476	<xs:simpleContent>
			477	<xs:restriction base="utility:clinical_res_attributes">
			478	<xs:enumeration value="" />
			479	<xs:enumeration value="Cecum" />
			480	<xs:enumeration value="Ascending Colon" />
			481	<xs:enumeration value="Hepatic Flexure" />
			482	<xs:enumeration value="Transverse Colon" />
			483	<xs:enumeration value="Splenic Flexure" />
			484	<xs:enumeration value="Descending Colon" />
			485	<xs:enumeration value="Sigmoid Colon" />
			486	<xs:enumeration value="Rectosigmoid Junction" />
			487	<xs:attribute name="cde" type="xs:string" default="2716417" />
			488	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
			489	<xs:attribute name="tier" type="xs:string" default="2" />
			490	</xs:restriction>
			491	</xs:simpleContent>
			492	</xs:complexType>
			493	</xs:element>
		-+	496	<xs:element name="histological_type" nillable="true">
			497	<xs:complexType mixed="true">
			498	<xs:simpleContent>
			499	<xs:restriction base="utility:clinical_res_attributes">
			500	<xs:attribute name="cde" type="xs:string" default="3081934" />
			501	<xs:attribute name="xsd_ver" type="xs:string" default="1.9" />
			502	<xs:attribute name="tier" type="xs:string" default="1" />
			503	</xs:restriction>
			504	</xs:simpleContent>
			505	</xs:complexType>
			506	</xs:element>
		-+	508	<xs:element name="tumor_stage" nillable="true">
			509	<xs:complexType>
			510	<xs:simpleContent>
			511	<xs:restriction base="utility:clinical_res_attributes">
			512	<xs:enumeration value="" />
			513	<xs:enumeration value="Stage I" />
			514	<xs:enumeration value="Stage IA" />
			515	<xs:enumeration value="Stage IB" />
			516	<xs:enumeration value="Stage II" />
			517	<xs:enumeration value="Stage IIA" />
			518	<xs:enumeration value="Stage IIB" />
			519	<xs:enumeration value="Stage IIC" />
			520	<xs:enumeration value="Stage III" />
			521	<xs:enumeration value="Stage IIIA" />
			522	<xs:enumeration value="Stage IIIB" />
			523	<xs:enumeration value="Stage IIIC" />
			524	<xs:enumeration value="Stage IV" />
			525	<xs:enumeration value="Stage IVA" />
			526	<xs:enumeration value="Stage IVB" />
			527	<xs:attribute name="cde" type="xs:string" default="3065862" />
			528	<xs:attribute name="xsd_ver" type="xs:string" default="2.4" />
			529	<xs:attribute name="tier" type="xs:string" default="1" />
			530	</xs:restriction>
			531	</xs:simpleContent>
			532	</xs:complexType>
			533	</xs:element>
		-+	535	<xs:element name="residual_tumor" nillable="true">
			536	<xs:complexType>
			537	<xs:simpleContent>
			538	<xs:restriction base="utility:clinical_res_attributes">
			539	<xs:enumeration value="" />
			540	<xs:enumeration value="RX" />
			541	<xs:enumeration value="R0" />
			542	<xs:enumeration value="R1" />
			543	<xs:enumeration value="R2" />
			544	<xs:attribute name="cde" type="xs:string" default="2608702" />
			545	<xs:attribute name="xsd_ver" type="xs:string" default="1.11" />
			546	<xs:attribute name="tier" type="xs:string" default="1" />
			547	</xs:restriction>
			548	</xs:simpleContent>
			549	</xs:complexType>
			550	</xs:element>
		-+	552	<xs:element name="primary_tumor_pathologic_spread" nillable="true">
			553	<xs:complexType>
			554	<xs:simpleContent>
			555	<xs:restriction base="utility:clinical_res_attributes">
			556	<xs:enumeration value="" />
			557	<xs:enumeration value="TX" />
			558	<xs:enumeration value="Tis" />
			559	<xs:enumeration value="T0" />
			560	<xs:enumeration value="T1" />
			561	<xs:enumeration value="T2" />
			562	<xs:enumeration value="T2a" />
			563	<xs:enumeration value="T2b" />
			564	<xs:enumeration value="T3" />
			565	<xs:enumeration value="T4" />
			566	<xs:enumeration value="T4a" />
			567	<xs:enumeration value="T4b" />
			568	<xs:attribute name="cde" type="xs:string" default="3045435" />
			569	<xs:attribute name="xsd_ver" type="xs:string" default="2.1" />
			570	<xs:attribute name="tier" type="xs:string" default="1" />
			571	</xs:restriction>
			572	</xs:simpleContent>
			573	</xs:complexType>
			574	</xs:element>
		-+	576	<xs:element name="lymphnode_pathologic_spread" nillable="true">
			577	<xs:complexType>
			578	<xs:simpleContent>
			579	<xs:restriction base="utility:clinical_res_attributes">
			580	<xs:enumeration value="" />
			581	<xs:enumeration value="NX" />
			582	<xs:enumeration value="N0" />
			583	<xs:enumeration value="N1" />
			584	<xs:enumeration value="N1a" />
			585	<xs:enumeration value="N1b" />
			586	<xs:enumeration value="N1c" />
			587	<xs:enumeration value="N2" />
			588	<xs:enumeration value="N2a" />
			589	<xs:enumeration value="N2b" />
			590	<xs:attribute name="cde" type="xs:string" default="3065858" />
			591	<xs:attribute name="xsd_ver" type="xs:string" default="2.1" />
			592	<xs:attribute name="tier" type="xs:string" default="1" />
			593	</xs:restriction>
			594	</xs:simpleContent>
			595	</xs:complexType>
			596	</xs:element>
		-+	598	<xs:element name="distant_metastasis_pathologic_spread" nillable="true">
			599	<xs:complexType>
			600	<xs:simpleContent>
			601	<xs:restriction base="utility:clinical_res_attributes">
			602	<xs:enumeration value="" />
			603	<xs:enumeration value="M0" />
			604	<xs:enumeration value="M1" />
			605	<xs:enumeration value="M1a" />
			606	<xs:enumeration value="M1b" />
			607	<xs:enumeration value="MX" />
			608	<xs:attribute name="cde" type="xs:string" default="3045439" />
			609	<xs:attribute name="xsd_ver" type="xs:string" default="2.4" />
			610	<xs:attribute name="tier" type="xs:string" default="1" />
			611	</xs:restriction>
			612	</xs:simpleContent>
			613	</xs:complexType>
			614	</xs:element>
		-+	616	<xs:element name="number_of_lymphnodes_examined" nillable="true">
			617	<xs:complexType mixed="true">
			618	<xs:simpleContent>
			619	<xs:restriction base="utility:clinical_res_attributes">
			620	<xs:attribute name="cde" type="xs:string" default="3" />
			621	<xs:attribute name="xsd_ver" type="xs:string" default="2.1" />
			622	<xs:attribute name="tier" type="xs:string" default="1" />
			623	</xs:restriction>
			624	</xs:simpleContent>
			625	</xs:complexType>
			626	</xs:element>
		-+	628	<xs:element name="number_of_lymphnodes_positive_by_ihc" nillable="true">
			629	<xs:complexType mixed="true">
			630	<xs:simpleContent>
			631	<xs:restriction base="utility:clinical_res_attributes">
			632	<xs:attribute name="cde" type="xs:string" default="3086383" />
			633	<xs:attribute name="xsd_ver" type="xs:string" default="2.1" />
			634	<xs:attribute name="tier" type="xs:string" default="1" />
			635	</xs:restriction>
			636	</xs:simpleContent>
			637	</xs:complexType>
			638	</xs:element>

   
File: TCGA_BCR.COAD_Clinical_FollowUp_v1.0.xsd  

1	<?xml version="1.0" encoding="utf-8" ?>	+-
4	<xs:schema elementFormDefault="qualified" version="2.5.0"	+-
5	xmlns:xs="http://www.w3.org/2001/XMLSchema"
6	xmlns:shared="http://tcga.nci/bcr/xml/clinical/shared/2.5"
7	xmlns:utility="http://tcga.nci/bcr/xml/utility/2.5"
8	xmlns:admin="http://tcga.nci/bcr/xml/administration/2.5"
9	xmlns="http://tcga.nci/bcr/xml/clinical/coad/followup/2.5/1.0"
10	targetNamespace="http://tcga.nci/bcr/xml/clinical/coad/followup/2.5/1.0"
11	xmlns:jaxb="http://java.sun.com/xml/ns/jaxb" jaxb:version="1.0" >
13	<xs:import schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/utility/2.5/TCGA_BCR.Utility.xsd" namespace="http://tcga.nci/bcr/xml/utility/2.5" />	+-
14	<xs:import schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/administration/2.5/TCGA_BCR.Administration.xsd" namespace="http://tcga.nci/bcr/xml/administration/2.5" />
15	<xs:import schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/shared/2.5/TCGA_BCR.Shared_Clinical_Elements.xsd" namespace="http://tcga.nci/bcr/xml/clinical/shared/2.5" />
17	<xs:annotation>	+-
18	<xs:appinfo>
19	<jaxb:globalBindings generateIsSetMethod="true" />
20	<jaxb:schemaBindings>
21	<jaxb:package name="nci.tcga.bcr.xml.jaxb.clinical.coad" />
22	</jaxb:schemaBindings>
23	</xs:appinfo>
24	</xs:annotation>
26	<xs:annotation>	+-
27	<xs:documentation xml:lang="en">Schema to define the elements of the TCGA Clinical Data Follow-up Form within the coad study.</xs:documentation>
28	</xs:annotation>
30	<xs:element name="follow_up_v1.0">	+-
31	<xs:complexType>
32	<xs:sequence>
33	<xs:element ref="shared:bcr_patient_barcode" />
34	<xs:element ref="shared:bcr_patient_uuid" />
35	<xs:element ref="shared:vital_status" />
36	<xs:choice>
37	<xs:sequence>
38	<xs:element ref="shared:day_of_last_followup" />
39	<xs:element ref="shared:month_of_last_followup" />
40	<xs:element ref="shared:year_of_last_followup" />
41	</xs:sequence>
42	<xs:element ref="shared:days_to_last_followup" />
43	</xs:choice>
44	<xs:choice>
45	<xs:sequence>
46	<xs:element ref="shared:day_of_death" />
47	<xs:element ref="shared:month_of_death" />
48	<xs:element ref="shared:year_of_death" />
49	</xs:sequence>
50	<xs:element ref="shared:days_to_death" />
51	</xs:choice>
52	<xs:element ref="shared:new_tumor_event_after_initial_treatment" />
53	<xs:choice>
54	<xs:sequence>
55	<xs:element ref="shared:day_of_new_tumor_event_after_initial_treatment" />
56	<xs:element ref="shared:month_of_new_tumor_event_after_initial_treatment" />
57	<xs:element ref="shared:year_of_new_tumor_event_after_initial_treatment" />
58	</xs:sequence>
59	<xs:element ref="shared:days_to_new_tumor_event_after_initial_treatment" />
60	</xs:choice>
61	<xs:element ref="shared:additional_surgery_locoregional_procedure" />
62	<xs:choice>
63	<xs:sequence>
64	<xs:element ref="shared:day_of_additional_surgery_locoregional_procedure" />
65	<xs:element ref="shared:month_of_additional_surgery_locoregional_procedure" />
66	<xs:element ref="shared:year_of_additional_surgery_locoregional_procedure" />
67	</xs:sequence>
68	<xs:element ref="shared:days_to_additional_surgery_locoregional_procedure" />
69	</xs:choice>
70	<xs:element ref="shared:person_neoplasm_cancer_status" />
71	<xs:element ref="shared:radiation_therapy" />
72	<xs:element ref="shared:additional_radiation_therapy" />
73	<xs:element ref="shared:targeted_molecular_therapy" />
74	<xs:element ref="shared:additional_pharmaceutical_therapy" />
75	<xs:element ref="shared:additional_surgery_metastatic_procedure" />
76	<xs:choice>
77	<xs:sequence>
78	<xs:element ref="shared:day_of_additional_surgery_metastatic_procedure" />
79	<xs:element ref="shared:month_of_additional_surgery_metastatic_procedure" />
80	<xs:element ref="shared:year_of_additional_surgery_metastatic_procedure" />
81	</xs:sequence>
82	<xs:element ref="shared:days_to_additional_surgery_metastatic_procedure" />
83	</xs:choice>
84	<xs:choice>
85	<xs:sequence>
86	<xs:element ref="shared:day_of_form_completion" />
87	<xs:element ref="shared:month_of_form_completion" />
88	<xs:element ref="shared:year_of_form_completion" />
89	</xs:sequence>
90	<xs:element ref="shared:days_to_form_completion" />
91	</xs:choice>
93	<xs:element ref="shared:followup_case_report_form_submission_reason" />	+-
95	<xs:element ref="shared:residual_disease_post_new_tumor_event_margin_status" />	+-
96	<xs:element ref="site_of_additional_surgery_new_tumor_event_mets" />
98	</xs:sequence>	+-
99	<xs:attribute name="version" type="xs:string" default="1.0" use="optional"/>
100	</xs:complexType>
101	</xs:element>
103	<xs:element name="site_of_additional_surgery_new_tumor_event_mets">	+-
104	<xs:complexType>
105	<xs:simpleContent>
106	<xs:restriction base="utility:clinical_res_attributes">
107	<xs:enumeration value="" />
108	<xs:enumeration value="Liver" />
109	<xs:enumeration value="Lung" />
110	<xs:enumeration value="Lymph Nodes" />
111	<xs:enumeration value="Other" />
112	<xs:attribute name="cde" type="xs:string" default="1611" />
113	<xs:attribute name="xsd_ver" type="xs:string" default="2.5" />
114	<xs:attribute name="tier" type="xs:string" default="2" />
115	</xs:restriction>
116	</xs:simpleContent>
117	</xs:complexType>
118	</xs:element>
121	</xs:schema>	+-

   
File: TCGA_BCR.CQCF.xsd  

1	<?xml version="1.0" encoding="utf-8"?>	+-
3	<xs:schema xmlns:shared="http://tcga.nci/bcr/xml/clinical/shared/2.5" xmlns:utility="http://tcga.nci/bcr/xml/utility/2.5" xmlns="http://tcga.nci/bcr/xml/clinical/cqcf/2.5" xmlns:xs="http://www.w3.org/2001/XMLSchema" targetNamespace="http://tcga.nci/bcr/xml/clinical/cqcf/2.5" elementFormDefault="qualified" version="2.5.0">	+-
4	<xs:import namespace="http://tcga.nci/bcr/xml/utility/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/utility/2.5/TCGA_BCR.Utility.xsd"/>
5	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/shared/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/shared/2.5/TCGA_BCR.Shared_Clinical_Elements.xsd"/>
6	<xs:annotation>
7	<xs:documentation xml:lang="en">Schema to define the elements of the CQCF Data.</xs:documentation>
8	</xs:annotation>
9	<xs:element name="biospecimen_cqcf">
10	<xs:complexType>
11	<xs:sequence>
12	<xs:element ref="maximum_tumor_dimension"/>
13	<xs:choice>
14	<xs:sequence>
15	<xs:element ref="day_of_sample_procurement"/>
16	<xs:element ref="month_of_sample_procurement"/>
17	<xs:element ref="year_of_sample_procurement"/>
18	</xs:sequence>
19	<xs:element ref="days_to_sample_procurement"/>
20	</xs:choice>
21	<xs:element ref="method_of_sample_procurement"/>
22	<xs:element ref="country"/>
23	<xs:element ref="vessel_used"/>
24	<xs:element ref="submitted_for_lce"/>
25	<xs:element ref="sample_prescreened"/>
26	<xs:element ref="top_slide_submitted"/>
27	<xs:element ref="digital_image_submitted"/>
28	<xs:element ref="h_and_e_tumor_slide_submitted"/>
29	<xs:element ref="b_cell_tumor_slide_submitted"/>
30	<xs:element ref="t_cell_tumor_slide_submitted"/>
31	<xs:element ref="tumor_samples"/>
32	<xs:element ref="normal_controls"/>
33	<xs:choice>
34	<xs:sequence>
35	<xs:element ref="day_of_pathology_review"/>
36	<xs:element ref="month_of_pathology_review"/>
37	<xs:element ref="year_of_pathology_review"/>
38	</xs:sequence>
39	<xs:element ref="days_to_pathology_review"/>
40	</xs:choice>
41	<xs:element ref="path_confirm_tumor_nuclei_metrics"/>
42	<xs:element ref="path_confirm_tumor_necrosis_metrics"/>
43	<xs:element ref="path_confirm_report_attached"/>
44	<xs:element ref="path_confirm_diagnosis_matching"/>
45	<xs:element ref="reason_path_confirm_diagnosis_not_matching"/>
46	<xs:element ref="cytogenetic_report_submitted"/>
47	<xs:element ref="differential_report_submitted"/>
48	<xs:element ref="hiv_positive_status"/>
49	<xs:element ref="total_cells_submitted"/>
50	<xs:element ref="percent_myeloblasts_for_submitted_specimen"/>
51	</xs:sequence>
52	</xs:complexType>
53	</xs:element>
54	<xs:element name="tumor_samples">
55	<xs:complexType>
56	<xs:sequence>
57	<xs:element ref="tumor_sample" minOccurs="0" maxOccurs="unbounded"/>
58	</xs:sequence>
59	</xs:complexType>
60	</xs:element>
61	<xs:element name="tumor_sample">
62	<xs:complexType>
63	<xs:sequence>
64	<xs:element ref="vial_number"/>
65	<xs:element ref="bcr_sample_uuid"/>
66	<xs:element ref="tumor_weight"/>
67	<xs:element ref="tumor_nuclei_percent"/>
68	<xs:element ref="tumor_necrosis_percent"/>
69	<xs:element ref="tumor_pathology"/>
70	</xs:sequence>
71	</xs:complexType>
72	</xs:element>
73	<xs:element name="normal_controls">
74	<xs:complexType>
75	<xs:sequence>
76	<xs:element ref="normal_control" minOccurs="0" maxOccurs="unbounded"/>
77	</xs:sequence>
78	</xs:complexType>
79	</xs:element>
80	<xs:element name="normal_control">
81	<xs:complexType>
82	<xs:sequence>
83	<xs:element ref="vial_number"/>
84	<xs:element ref="bcr_sample_uuid"/>
85	<xs:element ref="normal_control_type"/>
86	<xs:element ref="method_of_normal_sample_procurement"/>
87	<xs:choice>
88	<xs:sequence>
89	<xs:element ref="day_of_normal_sample_procurement"/>
90	<xs:element ref="month_of_normal_sample_procurement"/>
91	<xs:element ref="year_of_normal_sample_procurement"/>
92	</xs:sequence>
93	<xs:element ref="days_to_normal_sample_procurement"/>
94	</xs:choice>
95	<xs:choice minOccurs="0" maxOccurs="1">
96	<xs:element ref="extracted_dna"/>
97	<xs:element ref="normal_tissue"/>
98	</xs:choice>
99	</xs:sequence>
100	</xs:complexType>
101	</xs:element>
102	<xs:element name="extracted_dna">
103	<xs:complexType>
104	<xs:sequence>
105	<xs:element ref="ncedna_dna_conc"/>
106	<xs:element ref="ncedna_dna_qm"/>
107	<xs:element ref="ncedna_dna_qty"/>
108	<xs:element ref="ncedna_dna_vol"/>
109	</xs:sequence>
110	</xs:complexType>
111	</xs:element>
112	<xs:element name="normal_tissue">
113	<xs:complexType>
114	<xs:sequence>
115	<xs:element ref="normal_tissue_anatomic_site"/>
116	<xs:element ref="normal_tissue_proximity"/>
117	</xs:sequence>
118	</xs:complexType>
119	</xs:element>
120	<xs:element name="vial_number" nillable="false">
121	<xs:complexType>
122	<xs:simpleContent>
123	<xs:restriction base="utility:common_res_attributes">
124	<xs:length value="1"/>
125	<xs:attribute name="cde" type="xs:string" default=""/>
126	<xs:attribute name="xsd_ver" type="xs:string" default="2.4"/>
127	</xs:restriction>
128	</xs:simpleContent>
129	</xs:complexType>
130	</xs:element>
131	<xs:element name="bcr_sample_uuid">
132	<xs:complexType>
133	<xs:simpleContent>
134	<xs:extension base="xs:string">
135	<xs:attributeGroup ref="utility:common_ext_attribute_group"/>
136	<xs:attribute name="cde" type="xs:string" default=""/>
137	<xs:attribute name="xsd_ver" type="xs:string" default="2.3"/>
138	</xs:extension>
139	</xs:simpleContent>
140	</xs:complexType>
141	</xs:element>
142	<xs:element name="consent_or_death_status">
143	<xs:complexType>
144	<xs:simpleContent>
145	<xs:restriction base="utility:clinical_res_attributes">
146	<xs:enumeration value=""/>
147	<xs:enumeration value="Consented"/>
148	<xs:enumeration value="Deceased"/>
149	<xs:enumeration value="Exemption 4"/>
150	<xs:enumeration value="Waiver"/>
151	<xs:attribute name="cde" type="xs:string" default="3288361"/>
152	<xs:attribute name="xsd_ver" type="xs:string" default="2.5"/>
153	<xs:attribute name="tier" type="xs:string" default="2"/>
154	</xs:restriction>
155	</xs:simpleContent>
156	</xs:complexType>
157	</xs:element>
158	<xs:element name="day_of_consent">
159	<xs:complexType mixed="true">
160	<xs:simpleContent>
161	<xs:extension base="utility:generic_day">
162	<xs:attributeGroup ref="utility:common_ext_attribute_group"/>
163	<xs:attribute name="cde" type="xs:string" default="3081957"/>
164	<xs:attribute name="xsd_ver" type="xs:string" default="2.5"/>
165	<xs:attribute name="tier" type="xs:string" default="2"/>
166	</xs:extension>
167	</xs:simpleContent>
168	</xs:complexType>
169	</xs:element>
170	<xs:element name="month_of_consent">
171	<xs:complexType mixed="true">
172	<xs:simpleContent>
173	<xs:extension base="utility:generic_month">
174	<xs:attributeGroup ref="utility:common_ext_attribute_group"/>
175	<xs:attribute name="cde" type="xs:string" default="3081955"/>
176	<xs:attribute name="xsd_ver" type="xs:string" default="2.5"/>
177	<xs:attribute name="tier" type="xs:string" default="2"/>
178	</xs:extension>
179	</xs:simpleContent>
180	</xs:complexType>
181	</xs:element>
182	<xs:element name="year_of_consent">
183	<xs:complexType mixed="true">
184	<xs:simpleContent>
185	<xs:extension base="utility:generic_year">
186	<xs:attributeGroup ref="utility:common_ext_attribute_group"/>
187	<xs:attribute name="cde" type="xs:string" default="3081959"/>
188	<xs:attribute name="xsd_ver" type="xs:string" default="2.5"/>
189	<xs:attribute name="tier" type="xs:string" default="2"/>
190	</xs:extension>
191	</xs:simpleContent>
192	</xs:complexType>
193	</xs:element>
194	<xs:element name="days_to_consent">
195	<xs:complexType mixed="true">
196	<xs:simpleContent>
197	<xs:restriction base="utility:clinical_res_attributes">
198	<xs:attribute name="cde" type="xs:string" default="3288498"/>
199	<xs:attribute name="xsd_ver" type="xs:string" default="2.5"/>
200	<xs:attribute name="tier" type="xs:string" default="1"/>
201	</xs:restriction>
202	</xs:simpleContent>
203	</xs:complexType>
204	</xs:element>
206	<xs:element name="prior_head_radiation_therapy">	+-
207	<xs:complexType>
208	<xs:simpleContent>
209	<xs:extension base="utility:yes_or_no">
210	<xs:attributeGroup ref="utility:common_ext_attribute_group"/>
211	<xs:attribute name="cde" type="xs:string" default="3120926"/>
212	<xs:attribute name="xsd_ver" type="xs:string" default="2.5"/>
213	<xs:attribute name="tier" type="xs:string" default="2"/>
214	</xs:extension>
215	</xs:simpleContent>
216	</xs:complexType>
217	</xs:element>
219	<xs:element name="diagnosis_subtype">	+-
220	<xs:complexType>
221	<xs:simpleContent>
222	<xs:restriction base="utility:clinical_res_attributes">
223	<xs:enumeration value=""/>
224	<xs:enumeration value="Non-papillary"/>
225	<xs:enumeration value="Papillary"/>
226	<xs:attribute name="cde" type="xs:string" default="2783887"/>
227	<xs:attribute name="xsd_ver" type="xs:string" default="2.5"/>
228	<xs:attribute name="tier" type="xs:string" default="2"/>
229	</xs:restriction>
230	</xs:simpleContent>
231	</xs:complexType>
232	</xs:element>
234	<xs:element name="history_of_neoadjuvant_treatment">	+-
235	<xs:complexType>
236	<xs:simpleContent>
237	<xs:extension base="xs:string">
238	<xs:attributeGroup ref="utility:common_ext_attribute_group"/>
239	<xs:attribute name="cde" type="xs:string" default=""/>
240	<xs:attribute name="xsd_ver" type="xs:string" default="2.5"/>
241	</xs:extension>
242	</xs:simpleContent>
243	</xs:complexType>
244	</xs:element>
246	<xs:element name="history_of_prior_malignancy">	+-
247	<xs:complexType>
248	<xs:simpleContent>
249	<xs:extension base="xs:string">
250	<xs:attributeGroup ref="utility:common_ext_attribute_group"/>
251	<xs:attribute name="cde" type="xs:string" default=""/>
252	<xs:attribute name="xsd_ver" type="xs:string" default="2.5"/>
253	</xs:extension>
254	</xs:simpleContent>
255	</xs:complexType>
256	</xs:element>
258	<xs:element name="normal_tissue_anatomic_site">	+-
259	<xs:complexType>
260	<xs:simpleContent>
261	<xs:restriction base="utility:clinical_res_attributes">
262	<xs:enumeration value=""/>
263	<xs:enumeration value="BLADDER"/>
264	<xs:enumeration value="BLOOD"/>
265	<xs:enumeration value="BONE MARROW"/>
266	<xs:enumeration value="BRAIN"/>
267	<xs:enumeration value="BREAST"/>
268	<xs:enumeration value="CENTRAL NERVOUS SYSTEM"/>
269	<xs:enumeration value="CERVIX"/>
270	<xs:enumeration value="COLON"/>
271	<xs:enumeration value="ENDOMETRIAL"/>
272	<xs:enumeration value="HEAD/NECK"/>
273	<xs:enumeration value="KIDNEY"/>
274	<xs:enumeration value="Liver"/>
275	<xs:enumeration value="LUNG"/>
276	<xs:enumeration value="LYMPH NODE"/>
277	<xs:enumeration value="OMENTUM"/>
278	<xs:enumeration value="OVARY"/>
279	<xs:enumeration value="PERITONEUM (OVARY)"/>
280	<xs:enumeration value="Prostate"/>
281	<xs:enumeration value="RECTUM"/>
282	<xs:enumeration value="STOMACH"/>
283	<xs:enumeration value="Thyroid gland"/>
284	<xs:enumeration value="Skin"/>
285	<xs:enumeration value="Subcutaneous tissue"/>
286	<xs:enumeration value="Lymph node(s) Regional"/>
287	<xs:enumeration value="Lymph node(s) Distant"/>
288	<xs:enumeration value="Other"/>
289	<xs:attribute name="cde" type="xs:string" default="3081938"/>
290	<xs:attribute name="xsd_ver" type="xs:string" default="2.5"/>
291	<xs:attribute name="tier" type="xs:string" default="2"/>
292	</xs:restriction>
293	</xs:simpleContent>
294	</xs:complexType>
295	</xs:element>
296	<xs:element name="normal_tissue_proximity">
297	<xs:complexType>
298	<xs:simpleContent>
299	<xs:restriction base="utility:clinical_res_attributes">
300	<xs:enumeration value=""/>
301	<xs:enumeration value="Distal (&gt;2cm)"/>
302	<xs:attribute name="cde" type="xs:string" default="3088708"/>
303	<xs:attribute name="xsd_ver" type="xs:string" default="2.5"/>
304	<xs:attribute name="tier" type="xs:string" default="2"/>
305	</xs:restriction>
306	</xs:simpleContent>
307	</xs:complexType>
308	</xs:element>
309	<xs:element name="other_anatomic_site_normal_tissue" nillable="true">
310	<xs:complexType>
311	<xs:simpleContent>
312	<xs:extension base="xs:string">
313	<xs:attributeGroup ref="utility:common_ext_attribute_group"/>
314	<xs:attribute name="cde" type="xs:string" default="3288189"/>
315	<xs:attribute name="xsd_ver" type="xs:string" default="2.5"/>
316	<xs:attribute name="tier" type="xs:string" default="2"/>
317	</xs:extension>
318	</xs:simpleContent>
319	</xs:complexType>
320	</xs:element>
321	<xs:element name="tumor_focality">
322	<xs:complexType>
323	<xs:simpleContent>
324	<xs:restriction base="utility:clinical_res_attributes">
325	<xs:enumeration value=""/>
326	<xs:enumeration value="Multifocal"/>
327	<xs:enumeration value="Unifocal"/>
328	<xs:attribute name="cde" type="xs:string" default="3174022"/>
329	<xs:attribute name="xsd_ver" type="xs:string" default="2.5"/>
330	<xs:attribute name="tier" type="xs:string" default="2"/>
331	</xs:restriction>
332	</xs:simpleContent>
333	</xs:complexType>
334	</xs:element>
335	<xs:element name="tumor_type">
336	<xs:complexType>
337	<xs:simpleContent>
338	<xs:restriction base="utility:clinical_res_attributes">
339	<xs:enumeration value=""/>
340	<xs:enumeration value="Metastatic"/>
341	<xs:enumeration value="Recurrent"/>
342	<xs:enumeration value="Primary"/>
343	<xs:enumeration value="Tumor specimen from de novo untreated malignancy of the bladder"/>
344	<xs:attribute name="cde" type="xs:string" default="3288124"/>
345	<xs:attribute name="xsd_ver" type="xs:string" default="2.5"/>
346	<xs:attribute name="tier" type="xs:string" default="2"/>
347	</xs:restriction>
348	</xs:simpleContent>
349	</xs:complexType>
350	</xs:element>
351	<xs:element name="other_diagnosis" nillable="true">
352	<xs:complexType>
353	<xs:simpleContent>
354	<xs:extension base="xs:string">
355	<xs:attributeGroup ref="utility:common_ext_attribute_group"/>
356	<xs:attribute name="cde" type="xs:string" default="3124492"/>
357	<xs:attribute name="xsd_ver" type="xs:string" default="2.5"/>
358	<xs:attribute name="tier" type="xs:string" default="2"/>
359	</xs:extension>
360	</xs:simpleContent>
361	</xs:complexType>
362	</xs:element>
363	<xs:element name="aml_world_health_organization">
364	<xs:complexType>
365	<xs:simpleContent>
366	<xs:restriction base="utility:clinical_res_attributes">
367	<xs:enumeration value=""/>
368	<xs:enumeration value="Acute basophilic leukemia"/>
369	<xs:enumeration value="Acute erythroid leukemia"/>
370	<xs:enumeration value="Acute megakaryoblastic leukemia"/>
371	<xs:enumeration value="Acute monoblastic/monocytic leukemia"/>
372	<xs:enumeration value="Acute myelomonocytic leukemia"/>
373	<xs:enumeration value="Acute panmyelosis with myelofibrosis"/>
374	<xs:enumeration value="AML (megakaryoblastic) with t(1;22) (p13;q13); RBM15-MKL1"/>
375	<xs:enumeration value="AML with inv(16)(p13q22) or t(16;16) (p13.1;q22), (CBFß/MYH11)"/>
376	<xs:enumeration value="AML with inv(3)(q21;q26.2) or t(3;3) (q21;q26.2);RPNI-EVI1"/>
377	<xs:enumeration value="AML with maturation"/>
378	<xs:enumeration value="AML with minimal differentiation"/>
379	<xs:enumeration value="AML with mutated CEBPA"/>
380	<xs:enumeration value="AML with mutated NPM1"/>
381	<xs:enumeration value="AML with myelodysplasia-related changes"/>
382	<xs:enumeration value="AML with t(6;9)(p23;q34);DEK-NUP214"/>
383	<xs:enumeration value="AML with t(8;21)(q22;q22), RUNX1 RUNX1T1"/>
384	<xs:enumeration value="AML with t(9;11)(p22;q33);MLLT3-MLL"/>
385	<xs:enumeration value="AML without maturation"/>
386	<xs:enumeration value="Classified by FAB Only"/>
387	<xs:enumeration value="Erythroleukemia, erythroid/myeloid"/>
388	<xs:attribute name="cde" type="xs:string" default="3257714"/>
389	<xs:attribute name="xsd_ver" type="xs:string" default="2.5"/>
390	<xs:attribute name="tier" type="xs:string" default="2"/>
391	</xs:restriction>
392	</xs:simpleContent>
393	</xs:complexType>
394	</xs:element>
395	<xs:element name="fab_category">
396	<xs:complexType>
397	<xs:simpleContent>
398	<xs:restriction base="utility:clinical_res_attributes">
399	<xs:enumeration value=""/>
400	<xs:enumeration value="Biphenotypic"/>
401	<xs:enumeration value="M0 Undifferentiated"/>
402	<xs:enumeration value="M1"/>
403	<xs:enumeration value="M2"/>
404	<xs:enumeration value="M3"/>
405	<xs:enumeration value="M3v"/>
406	<xs:enumeration value="M4"/>
407	<xs:enumeration value="M4EOS"/>
408	<xs:enumeration value="M5"/>
409	<xs:enumeration value="M6"/>
410	<xs:enumeration value="M7"/>
411	<xs:enumeration value="Not classified"/>
412	<xs:enumeration value="Not Classified"/>
413	<xs:enumeration value="Not Classified"/>
414	<xs:attribute name="cde" type="xs:string" default="3124352"/>
415	<xs:attribute name="xsd_ver" type="xs:string" default="2.5"/>
416	<xs:attribute name="tier" type="xs:string" default="2"/>
417	</xs:restriction>
418	</xs:simpleContent>
419	</xs:complexType>
420	</xs:element>
421	<xs:element name="diagnosis_cytogenetic_analysis">
422	<xs:complexType>
423	<xs:simpleContent>
424	<xs:restriction base="utility:clinical_res_attributes">
425	<xs:enumeration value=""/>
426	<xs:enumeration value="TDT Negative"/>
427	<xs:enumeration value="NSE Positive"/>
428	<xs:enumeration value="NSE Not Tested"/>
429	<xs:enumeration value="NSE Negative"/>
430	<xs:enumeration value="MPX Not Tested"/>
431	<xs:enumeration value="MPX Positive"/>
432	<xs:enumeration value="MPX Negative"/>
433	<xs:enumeration value="NA Not Tested"/>
434	<xs:enumeration value="NA Positive"/>
435	<xs:enumeration value="NA Negative"/>
436	<xs:enumeration value="CD56 Not Tested"/>
437	<xs:enumeration value="CD56 Positive"/>
438	<xs:enumeration value="CD56 Negative"/>
439	<xs:enumeration value="CD45 Not Tested"/>
440	<xs:enumeration value="CD45 Positive"/>
441	<xs:enumeration value="CD45 Negative"/>
442	<xs:enumeration value="CD34 Not Tested"/>
443	<xs:enumeration value="CD34 Positive"/>
444	<xs:enumeration value="CD34 Negative"/>
445	<xs:enumeration value="CD33 Not Tested"/>
446	<xs:enumeration value="CD33 Positive"/>
447	<xs:enumeration value="CD33 Negative"/>
448	<xs:enumeration value="CD25 Not Tested"/>
449	<xs:enumeration value="CD25 Positive"/>
450	<xs:enumeration value="CD25 Negative"/>
451	<xs:enumeration value="CD23 Not Tested"/>
452	<xs:enumeration value="CD23 Positive"/>
453	<xs:enumeration value="CD23 Negative"/>
454	<xs:enumeration value="CD20 Not Tested"/>
455	<xs:enumeration value="CD20 Positive"/>
456	<xs:enumeration value="CD20 Negative"/>
457	<xs:enumeration value="CD19 Not Tested"/>
458	<xs:enumeration value="CD19 Positive"/>
459	<xs:enumeration value="CD19 Negative"/>
460	<xs:enumeration value="CD15 Not Tested"/>
461	<xs:enumeration value="CD15 Positive"/>
462	<xs:enumeration value="CD15 Negative"/>
463	<xs:enumeration value="CD14 Not Tested"/>
464	<xs:enumeration value="CD14 Positive"/>
465	<xs:enumeration value="CD14 Negative"/>
466	<xs:enumeration value="CD10 Not Tested"/>
467	<xs:enumeration value="CD10 Positive"/>
468	<xs:enumeration value="CD10 Negative"/>
469	<xs:enumeration value="CD7 Not Tested"/>
470	<xs:enumeration value="CD7 Positive"/>
471	<xs:enumeration value="CD7 Negative"/>
472	<xs:enumeration value="CD5 Not Tested"/>
473	<xs:enumeration value="CD5 Positive"/>
474	<xs:enumeration value="CD5 Negative"/>
475	<xs:enumeration value="CD3 Not Tested"/>
476	<xs:enumeration value="CD3 Positive"/>
477	<xs:enumeration value="CD3 Negative"/>
478	<xs:enumeration value="TDT Not Tested"/>
479	<xs:enumeration value="TDT Positive"/>
480	<xs:enumeration value="Other CD Not Tested"/>
481	<xs:enumeration value="Other CD Positive"/>
482	<xs:enumeration value="Other CD Negative"/>
483	<xs:enumeration value="HLA-DR Not Tested"/>
484	<xs:enumeration value="HLA-DR Positive"/>
485	<xs:enumeration value="HLA-DR  Negative"/>
486	<xs:enumeration value="CD 117 Not Tested"/>
487	<xs:enumeration value="CD117 Positive"/>
488	<xs:enumeration value="CD117 Negative"/>
489	<xs:enumeration value="CD13 Not Tested"/>
490	<xs:enumeration value="CD13 Positive"/>
491	<xs:enumeration value="CD13 Negative"/>
492	<xs:attribute name="cde" type="xs:string" default="3121483"/>
493	<xs:attribute name="xsd_ver" type="xs:string" default="2.5"/>
494	<xs:attribute name="tier" type="xs:string" default="2"/>
495	</xs:restriction>
496	</xs:simpleContent>
497	</xs:complexType>
498	</xs:element>
499	<xs:element name="histological_subtype">
500	<xs:complexType>
501	<xs:simpleContent>
502	<xs:restriction base="utility:clinical_res_attributes">
503	<xs:enumeration value=""/>
504	<xs:attribute name="cde" type="xs:string" default="3081934"/>
505	<xs:attribute name="xsd_ver" type="xs:string" default="2.5"/>
506	<xs:attribute name="tier" type="xs:string" default="2"/>
507	</xs:restriction>
508	</xs:simpleContent>
509	</xs:complexType>
510	</xs:element>
511	<xs:element name="nodal_anatomic_site">
512	<xs:complexType>
513	<xs:simpleContent>
514	<xs:restriction base="utility:clinical_res_attributes">
515	<xs:enumeration value=""/>
516	<xs:attribute name="cde" type="xs:string" default="2180591"/>
517	<xs:attribute name="xsd_ver" type="xs:string" default="2.5"/>
518	<xs:attribute name="tier" type="xs:string" default="2"/>
519	</xs:restriction>
520	</xs:simpleContent>
521	</xs:complexType>
522	</xs:element>
523	<xs:element name="extranodal_anatomic_site">
524	<xs:complexType>
525	<xs:simpleContent>
526	<xs:restriction base="utility:clinical_res_attributes">
527	<xs:enumeration value=""/>
528	<xs:attribute name="cde" type="xs:string" default="3153874"/>
529	<xs:attribute name="xsd_ver" type="xs:string" default="2.5"/>
530	<xs:attribute name="tier" type="xs:string" default="2"/>
531	</xs:restriction>
532	</xs:simpleContent>
533	</xs:complexType>
534	</xs:element>
536	<xs:element name="frozen_specimen_anatomic_site" nillable="true">	+-
537	<xs:complexType>
538	<xs:simpleContent>
539	<xs:restriction base="utility:clinical_res_attributes">
540	<xs:enumeration value="" />
541	<xs:enumeration value="Cecum" />
542	<xs:enumeration value="Ascending Colon" />
543	<xs:enumeration value="Hepatic Flexure" />
544	<xs:enumeration value="Transverse Colon" />
545	<xs:enumeration value="Splenic Flexure" />
546	<xs:enumeration value="Descending Colon" />
547	<xs:enumeration value="Sigmoid Colon" />
548	<xs:enumeration value="Oral Cavity" />
549	<xs:enumeration value="Lip" />
550	<xs:enumeration value="Tongue" />
551	<xs:enumeration value="Alveolar Ridge" />
552	<xs:enumeration value="Floor of Mouth" />
553	<xs:enumeration value="Hard Palate" />
554	<xs:enumeration value="Buccal Mucosa" />
555	<xs:enumeration value="Oropharynx" />
556	<xs:enumeration value="Tonsil" />
557	<xs:enumeration value="Base of Tongue" />
558	<xs:enumeration value="Hypopharynx" />
559	<xs:enumeration value="Larynx" />
560	<xs:enumeration value="Supratentorial" />
561	<xs:enumeration value="Spinal Cord" />
562	<xs:enumeration value="Posterior Fossa" />
563	<xs:enumeration value="Location Not Specified" />
564	<xs:enumeration value="Prostate" />
565	<xs:enumeration value="Seminal Vesicle" />
566	<xs:enumeration value="Rectosigmoid Junction" />
567	<xs:enumeration value="Rectum" />
568	<xs:enumeration value="Gastroesophageal Junction" />
569	<xs:enumeration value="Cardia/Proximal" />
570	<xs:enumeration value="Fundus/Body" />
571	<xs:enumeration value="Antrum/Distal" />
572	<xs:attribute name="cde" type="xs:string" default="3081961" />
573	<xs:attribute name="xsd_ver" type="xs:string" default="2.5" />
574	<xs:attribute name="tier" type="xs:string" default="1" />
575	</xs:restriction>
576	</xs:simpleContent>
577	</xs:complexType>
578	</xs:element>
580	<xs:element name="other_anatomic_site" nillable="true">	+-
581	<xs:complexType>
582	<xs:simpleContent>
583	<xs:extension base="xs:string">
584	<xs:attributeGroup ref="utility:common_ext_attribute_group"/>
585	<xs:attribute name="cde" type="xs:string" default="3320289"/>
586	<xs:attribute name="xsd_ver" type="xs:string" default="2.5"/>
587	<xs:attribute name="tier" type="xs:string" default="2"/>
588	</xs:extension>
589	</xs:simpleContent>
590	</xs:complexType>
591	</xs:element>
592	<xs:element name="country" nillable="true">
593	<xs:complexType>
594	<xs:simpleContent>
595	<xs:extension base="xs:string">
596	<xs:attributeGroup ref="utility:common_ext_attribute_group"/>
597	<xs:attribute name="cde" type="xs:string" default="3203072"/>
598	<xs:attribute name="xsd_ver" type="xs:string" default="2.5"/>
599	<xs:attribute name="tier" type="xs:string" default="2"/>
600	</xs:extension>
601	</xs:simpleContent>
602	</xs:complexType>
603	</xs:element>
604	<xs:element name="digital_image_submitted">
605	<xs:complexType>
606	<xs:simpleContent>
607	<xs:extension base="utility:yes_or_no">
608	<xs:attributeGroup ref="utility:common_ext_attribute_group"/>
609	<xs:attribute name="cde" type="xs:string" default="3081948"/>
610	<xs:attribute name="xsd_ver" type="xs:string" default="1.8"/>
611	</xs:extension>
612	</xs:simpleContent>
613	</xs:complexType>
614	</xs:element>
615	<xs:element name="pcr_amplification_successful">
616	<xs:complexType mixed="true">
617	<xs:simpleContent>
618	<xs:restriction base="utility:common_res_attributes">
619	<xs:attribute name="xsd_ver" type="xs:string" default="1.8"/>
620	</xs:restriction>
621	</xs:simpleContent>
622	</xs:complexType>
623	</xs:element>
624	<xs:element name="ncedna_dna_qm" default="" nillable="true">
625	<xs:complexType mixed="true">
626	<xs:simpleContent>
627	<xs:restriction base="utility:common_res_attributes">
628	<xs:attribute name="cde" type="xs:string" default="3288186"/>
629	<xs:attribute name="xsd_ver" type="xs:string" default="2.5"/>
630	</xs:restriction>
631	</xs:simpleContent>
632	</xs:complexType>
633	</xs:element>
634	<xs:element name="ncedna_dna_qty" default="" nillable="true">
635	<xs:complexType mixed="true">
636	<xs:simpleContent>
637	<xs:restriction base="utility:common_res_attributes">
638	<xs:attribute name="cde" type="xs:string" default="3288185"/>
639	<xs:attribute name="xsd_ver" type="xs:string" default="2.5"/>
640	</xs:restriction>
641	</xs:simpleContent>
642	</xs:complexType>
643	</xs:element>
644	<xs:element name="ncedna_dna_conc" default="" nillable="true">
645	<xs:complexType mixed="true">
646	<xs:simpleContent>
647	<xs:restriction base="utility:common_res_attributes">
648	<xs:attribute name="cde" type="xs:string" default="3288187"/>
649	<xs:attribute name="xsd_ver" type="xs:string" default="2.5"/>
650	</xs:restriction>
651	</xs:simpleContent>
652	</xs:complexType>
653	</xs:element>
654	<xs:element name="ncedna_dna_vol" default="" nillable="true">
655	<xs:complexType mixed="true">
656	<xs:simpleContent>
657	<xs:restriction base="utility:common_res_attributes">
658	<xs:attribute name="cde" type="xs:string" default="3288188"/>
659	<xs:attribute name="xsd_ver" type="xs:string" default="2.5"/>
660	</xs:restriction>
661	</xs:simpleContent>
662	</xs:complexType>
663	</xs:element>
664	<xs:element name="tumor_necrosis_percent" nillable="true">
665	<xs:complexType mixed="true">
666	<xs:simpleContent>
667	<xs:restriction base="utility:common_res_attributes">
668	<xs:attribute name="cde" type="xs:string" default="2841237"/>
669	<xs:attribute name="xsd_ver" type="xs:string" default="2.5"/>
670	</xs:restriction>
671	</xs:simpleContent>
672	</xs:complexType>
673	</xs:element>
674	<xs:element name="normal_control_type" nillable="true">
675	<xs:complexType mixed="true">
676	<xs:simpleContent>
677	<xs:restriction base="utility:common_res_attributes">
678	<xs:attribute name="cde" type="xs:string" default="3081936"/>
679	<xs:attribute name="xsd_ver" type="xs:string" default="2.5"/>
680	</xs:restriction>
681	</xs:simpleContent>
682	</xs:complexType>
683	</xs:element>
684	<xs:element name="other_vessel_used" default="" nillable="true">
685	<xs:complexType mixed="true">
686	<xs:simpleContent>
687	<xs:restriction base="utility:common_res_attributes">
688	<xs:attribute name="cde" type="xs:string" default="3288137"/>
689	<xs:attribute name="xsd_ver" type="xs:string" default="2.5"/>
690	</xs:restriction>
691	</xs:simpleContent>
692	</xs:complexType>
693	</xs:element>
694	<xs:element name="path_confirm_report_attached" default="" nillable="true">
695	<xs:complexType>
696	<xs:simpleContent>
697	<xs:extension base="utility:yes_or_no">
698	<xs:attributeGroup ref="utility:common_ext_attribute_group"/>
699	<xs:attribute name="cde" type="xs:string" default="3288292"/>
700	<xs:attribute name="xsd_ver" type="xs:string" default="2.5"/>
701	<xs:attribute name="tier" type="xs:string" default="1"/>
702	</xs:extension>
703	</xs:simpleContent>
704	</xs:complexType>
705	</xs:element>
706	<xs:element name="path_confirm_tumor_necrosis_metrics" nillable="true">
707	<xs:complexType>
708	<xs:simpleContent>
709	<xs:extension base="utility:yes_or_no">
710	<xs:attributeGroup ref="utility:common_ext_attribute_group"/>
711	<xs:attribute name="cde" type="xs:string" default="3288524"/>
712	<xs:attribute name="xsd_ver" type="xs:string" default="2.5"/>
713	<xs:attribute name="tier" type="xs:string" default="1"/>
714	</xs:extension>
715	</xs:simpleContent>
716	</xs:complexType>
717	</xs:element>
718	<xs:element name="path_confirm_tumor_nuclei_metrics" nillable="true">
719	<xs:complexType>
720	<xs:simpleContent>
721	<xs:extension base="utility:yes_or_no">
722	<xs:attributeGroup ref="utility:common_ext_attribute_group"/>
723	<xs:attribute name="cde" type="xs:string" default="3288520"/>
724	<xs:attribute name="xsd_ver" type="xs:string" default="2.5"/>
725	<xs:attribute name="tier" type="xs:string" default="1"/>
726	</xs:extension>
727	</xs:simpleContent>
728	</xs:complexType>
729	</xs:element>
730	<xs:element name="sample_prescreened" default="" nillable="true">
731	<xs:complexType mixed="true">
732	<xs:simpleContent>
733	<xs:extension base="utility:yes_or_no">
734	<xs:attributeGroup ref="utility:common_ext_attribute_group"/>
735	<xs:attribute name="cde" type="xs:string" default="3081942"/>
736	<xs:attribute name="xsd_ver" type="xs:string" default="2.5"/>
737	<xs:attribute name="tier" type="xs:string" default="2"/>
738	</xs:extension>
739	</xs:simpleContent>
740	</xs:complexType>
741	</xs:element>
742	<xs:element name="top_slide_submitted" default="" nillable="true">
743	<xs:complexType>
744	<xs:simpleContent>
745	<xs:extension base="utility:yes_or_no">
746	<xs:attributeGroup ref="utility:common_ext_attribute_group"/>
747	<xs:attribute name="cde" type="xs:string" default="3081948"/>
748	<xs:attribute name="xsd_ver" type="xs:string" default="1.8"/>
749	</xs:extension>
750	</xs:simpleContent>
751	</xs:complexType>
752	</xs:element>
753	<xs:element name="tumor_nuclei_percent" default="" nillable="true">
754	<xs:complexType mixed="true">
755	<xs:simpleContent>
756	<xs:restriction base="utility:common_res_attributes">
757	<xs:attribute name="cde" type="xs:string" default="2841225"/>
758	<xs:attribute name="xsd_ver" type="xs:string" default="2.5"/>
759	</xs:restriction>
760	</xs:simpleContent>
761	</xs:complexType>
762	</xs:element>
763	<xs:element name="vessel_used" default="" nillable="true">
764	<xs:complexType mixed="true">
765	<xs:simpleContent>
766	<xs:restriction base="utility:common_res_attributes">
767	<xs:attribute name="cde" type="xs:string" default="3081940"/>
768	<xs:attribute name="xsd_ver" type="xs:string" default="2.5"/>
769	</xs:restriction>
770	</xs:simpleContent>
771	</xs:complexType>
772	</xs:element>
773	<xs:element name="method_of_normal_sample_procurement" default="" nillable="true">
774	<xs:complexType mixed="true">
775	<xs:simpleContent>
776	<xs:restriction base="utility:common_res_attributes">
777	<xs:attribute name="cde" type="xs:string" default="3288147"/>
778	<xs:attribute name="xsd_ver" type="xs:string" default="2.5"/>
779	</xs:restriction>
780	</xs:simpleContent>
781	</xs:complexType>
782	</xs:element>
783	<xs:element name="tumor_weight" default="" nillable="true">
784	<xs:complexType mixed="true">
785	<xs:simpleContent>
786	<xs:restriction base="utility:common_res_attributes">
787	<xs:attribute name="cde" type="xs:string" default="3081946"/>
788	<xs:attribute name="xsd_ver" type="xs:string" default="2.5"/>
789	</xs:restriction>
790	</xs:simpleContent>
791	</xs:complexType>
792	</xs:element>
793	<xs:element name="year_of_cancer_sample_procurement" default="" nillable="true">
794	<xs:complexType mixed="true">
795	<xs:simpleContent>
796	<xs:restriction base="utility:common_res_attributes">
797	<xs:attribute name="cde" type="xs:string" default="3008199"/>
798	<xs:attribute name="xsd_ver" type="xs:string" default="2.5"/>
799	</xs:restriction>
800	</xs:simpleContent>
801	</xs:complexType>
802	</xs:element>
803	<xs:element name="sample_type_of_frozen_biospecimen_submitted" default="" nillable="true">
804	<xs:complexType mixed="true">
805	<xs:simpleContent>
806	<xs:restriction base="utility:common_res_attributes">
807	<xs:attribute name="cde" type="xs:string" default="3220470"/>
808	<xs:attribute name="xsd_ver" type="xs:string" default="2.5"/>
809	</xs:restriction>
810	</xs:simpleContent>
811	</xs:complexType>
812	</xs:element>
813	<xs:element name="total_cells_submitted" default="" nillable="true">
814	<xs:complexType mixed="true">
815	<xs:simpleContent>
816	<xs:restriction base="utility:common_res_attributes">
817	<xs:attribute name="cde" type="xs:string" default=""/>
818	<xs:attribute name="xsd_ver" type="xs:string" default="2.5"/>
819	</xs:restriction>
820	</xs:simpleContent>
821	</xs:complexType>
822	</xs:element>
823	<xs:element name="percent_myeloblasts_for_submitted_specimen" default="" nillable="true">
824	<xs:complexType mixed="true">
825	<xs:simpleContent>
826	<xs:restriction base="utility:common_res_attributes">
827	<xs:attribute name="cde" type="xs:string" default=""/>
828	<xs:attribute name="xsd_ver" type="xs:string" default="2.5"/>
829	</xs:restriction>
830	</xs:simpleContent>
831	</xs:complexType>
832	</xs:element>
833	<xs:element name="cytogenetic_report_submitted" nillable="true">
834	<xs:complexType>
835	<xs:simpleContent>
836	<xs:extension base="xs:string">
837	<xs:attributeGroup ref="utility:common_ext_attribute_group"/>
838	<xs:attribute name="cde" type="xs:string" default=""/>
839	<xs:attribute name="xsd_ver" type="xs:string" default="2.5"/>
840	</xs:extension>
841	</xs:simpleContent>
842	</xs:complexType>
843	</xs:element>
844	<xs:element name="other_method_of_normal_sample_procurement" default="" nillable="true">
845	<xs:complexType mixed="true">
846	<xs:simpleContent>
847	<xs:restriction base="utility:common_res_attributes">
848	<xs:attribute name="cde" type="xs:string" default="2006730"/>
849	<xs:attribute name="xsd_ver" type="xs:string" default="2.5"/>
850	</xs:restriction>
851	</xs:simpleContent>
852	</xs:complexType>
853	</xs:element>
854	<xs:element name="path_confirm_diagnosis_matching" default="" nillable="true">
855	<xs:complexType>
856	<xs:simpleContent>
857	<xs:extension base="utility:yes_or_no">
858	<xs:attributeGroup ref="utility:common_ext_attribute_group"/>
859	<xs:attribute name="cde" type="xs:string" default="3288300"/>
860	<xs:attribute name="xsd_ver" type="xs:string" default="1.8"/>
861	</xs:extension>
862	</xs:simpleContent>
863	</xs:complexType>
864	</xs:element>
865	<xs:element name="day_of_sample_procurement" default="">
866	<xs:complexType mixed="true">
867	<xs:simpleContent>
868	<xs:extension base="utility:generic_day">
869	<xs:attributeGroup ref="utility:common_ext_attribute_group"/>
870	<xs:attribute name="cde" type="xs:string" default="3008195"/>
871	<xs:attribute name="xsd_ver" type="xs:string" default="2.3"/>
872	</xs:extension>
873	</xs:simpleContent>
874	</xs:complexType>
875	</xs:element>
876	<xs:element name="month_of_sample_procurement" default="">
877	<xs:complexType mixed="true">
878	<xs:simpleContent>
879	<xs:extension base="utility:generic_month">
880	<xs:attributeGroup ref="utility:common_ext_attribute_group"/>
881	<xs:attribute name="cde" type="xs:string" default="3008197"/>
882	<xs:attribute name="xsd_ver" type="xs:string" default="2.3"/>
883	</xs:extension>
884	</xs:simpleContent>
885	</xs:complexType>
886	</xs:element>
887	<xs:element name="year_of_sample_procurement" default="">
888	<xs:complexType mixed="true">
889	<xs:simpleContent>
890	<xs:extension base="utility:generic_year">
891	<xs:attributeGroup ref="utility:common_ext_attribute_group"/>
892	<xs:attribute name="cde" type="xs:string" default="3008199"/>
893	<xs:attribute name="xsd_ver" type="xs:string" default="2.3"/>
894	</xs:extension>
895	</xs:simpleContent>
896	</xs:complexType>
897	</xs:element>
898	<xs:element name="day_of_pathology_review" default="">
899	<xs:complexType mixed="true">
900	<xs:simpleContent>
901	<xs:extension base="utility:generic_day">
902	<xs:attributeGroup ref="utility:common_ext_attribute_group"/>
903	<xs:attribute name="cde" type="xs:string" default=""/>
904	<xs:attribute name="xsd_ver" type="xs:string" default="2.5"/>
905	</xs:extension>
906	</xs:simpleContent>
907	</xs:complexType>
908	</xs:element>
909	<xs:element name="month_of_pathology_review" default="">
910	<xs:complexType mixed="true">
911	<xs:simpleContent>
912	<xs:extension base="utility:generic_month">
913	<xs:attributeGroup ref="utility:common_ext_attribute_group"/>
914	<xs:attribute name="cde" type="xs:string" default=""/>
915	<xs:attribute name="xsd_ver" type="xs:string" default="2.5"/>
916	</xs:extension>
917	</xs:simpleContent>
918	</xs:complexType>
919	</xs:element>
920	<xs:element name="year_of_pathology_review" default="">
921	<xs:complexType mixed="true">
922	<xs:simpleContent>
923	<xs:extension base="utility:generic_year">
924	<xs:attributeGroup ref="utility:common_ext_attribute_group"/>
925	<xs:attribute name="cde" type="xs:string" default=""/>
926	<xs:attribute name="xsd_ver" type="xs:string" default="2.5"/>
927	</xs:extension>
928	</xs:simpleContent>
929	</xs:complexType>
930	</xs:element>
931	<xs:element name="day_of_normal_sample_procurement" default="">
932	<xs:complexType mixed="true">
933	<xs:simpleContent>
934	<xs:extension base="utility:generic_day">
935	<xs:attributeGroup ref="utility:common_ext_attribute_group"/>
936	<xs:attribute name="cde" type="xs:string" default="3288196"/>
937	<xs:attribute name="xsd_ver" type="xs:string" default="2.3"/>
938	</xs:extension>
939	</xs:simpleContent>
940	</xs:complexType>
941	</xs:element>
942	<xs:element name="month_of_normal_sample_procurement" default="">
943	<xs:complexType mixed="true">
944	<xs:simpleContent>
945	<xs:extension base="utility:generic_month">
946	<xs:attributeGroup ref="utility:common_ext_attribute_group"/>
947	<xs:attribute name="cde" type="xs:string" default="3288195"/>
948	<xs:attribute name="xsd_ver" type="xs:string" default="2.3"/>
949	</xs:extension>
950	</xs:simpleContent>
951	</xs:complexType>
952	</xs:element>
953	<xs:element name="year_of_normal_sample_procurement" default="">
954	<xs:complexType mixed="true">
955	<xs:simpleContent>
956	<xs:extension base="utility:generic_year">
957	<xs:attributeGroup ref="utility:common_ext_attribute_group"/>
958	<xs:attribute name="cde" type="xs:string" default="3288197"/>
959	<xs:attribute name="xsd_ver" type="xs:string" default="2.3"/>
960	</xs:extension>
961	</xs:simpleContent>
962	</xs:complexType>
963	</xs:element>
964	<xs:element name="tumor_pathology">
965	<xs:complexType>
966	<xs:sequence>
967	<xs:element ref="primary_or_metastatic_status" minOccurs="0"/>
968	<xs:element ref="margins_involved" minOccurs="0"/>
969	<xs:element ref="venous_invasion" minOccurs="0"/>
970	<xs:element ref="lymphatic_invasion" minOccurs="0"/>
971	<xs:element ref="number_regional_lymphnodes_exam" minOccurs="0"/>
972	<xs:element ref="number_regional_lymphnodes_pos" minOccurs="0"/>
973	<xs:element ref="verification_by_bcr" minOccurs="0"/>
974	<xs:element ref="type" minOccurs="0"/>
975	</xs:sequence>
976	</xs:complexType>
977	</xs:element>
978	<xs:element name="primary_or_metastatic_status">
979	<xs:complexType>
980	<xs:simpleContent>
981	<xs:restriction base="utility:common_res_attributes">
982	<xs:enumeration value=""/>
983	<xs:enumeration value="PRIMARY"/>
984	<xs:enumeration value="METASTATIC"/>
985	<xs:enumeration value="MALIGNANT"/>
986	<xs:enumeration value="NON-MALIGNANT"/>
987	<xs:attribute name="cde" type="xs:string" default="2673765"/>
988	<xs:attribute name="xsd_ver" type="xs:string" default="1.8"/>
989	</xs:restriction>
990	</xs:simpleContent>
991	</xs:complexType>
992	</xs:element>
993	<xs:element name="margins_involved">
994	<xs:complexType>
995	<xs:simpleContent>
996	<xs:extension base="utility:yes_or_no">
997	<xs:attributeGroup ref="utility:common_ext_attribute_group"/>
998	<xs:attribute name="cde" type="xs:string" default="2608099"/>
999	<xs:attribute name="xsd_ver" type="xs:string" default="1.8"/>
1000	</xs:extension>
1001	</xs:simpleContent>
1002	</xs:complexType>
1003	</xs:element>
1004	<xs:element name="venous_invasion">
1005	<xs:complexType>
1006	<xs:simpleContent>
1007	<xs:extension base="utility:yes_or_no">
1008	<xs:attributeGroup ref="utility:common_ext_attribute_group"/>
1009	<xs:attribute name="cde" type="xs:string" default="64358"/>
1010	<xs:attribute name="xsd_ver" type="xs:string" default="1.8"/>
1011	</xs:extension>
1012	</xs:simpleContent>
1013	</xs:complexType>
1014	</xs:element>
1015	<xs:element name="lymphatic_invasion">
1016	<xs:complexType>
1017	<xs:simpleContent>
1018	<xs:extension base="utility:yes_or_no">
1019	<xs:attributeGroup ref="utility:common_ext_attribute_group"/>
1020	<xs:attribute name="cde" type="xs:string" default="64171"/>
1021	<xs:attribute name="xsd_ver" type="xs:string" default="1.8"/>
1022	</xs:extension>
1023	</xs:simpleContent>
1024	</xs:complexType>
1025	</xs:element>
1026	<xs:element name="number_regional_lymphnodes_exam">
1027	<xs:complexType>
1028	<xs:simpleContent>
1029	<xs:restriction base="utility:common_res_attributes">
1030	<xs:attribute name="cde" type="xs:string" default="2673768"/>
1031	<xs:attribute name="xsd_ver" type="xs:string" default="1.8"/>
1032	</xs:restriction>
1033	</xs:simpleContent>
1034	</xs:complexType>
1035	</xs:element>
1036	<xs:element name="number_regional_lymphnodes_pos">
1037	<xs:complexType>
1038	<xs:simpleContent>
1039	<xs:restriction base="utility:common_res_attributes">
1040	<xs:attribute name="cde" type="xs:string" default="2673770"/>
1041	<xs:attribute name="xsd_ver" type="xs:string" default="1.8"/>
1042	</xs:restriction>
1043	</xs:simpleContent>
1044	</xs:complexType>
1045	</xs:element>
1046	<xs:element name="verification_by_bcr">
1047	<xs:complexType>
1048	<xs:simpleContent>
1049	<xs:extension base="xs:NCName">
1050	<xs:attributeGroup ref="utility:common_ext_attribute_group"/>
1051	<xs:attribute name="cde" type="xs:string" default="2673771"/>
1052	<xs:attribute name="xsd_ver" type="xs:string" default="1.8"/>
1053	</xs:extension>
1054	</xs:simpleContent>
1055	</xs:complexType>
1056	</xs:element>
1057	<xs:element name="type">
1058	<xs:complexType mixed="true">
1059	<xs:choice minOccurs="0" maxOccurs="unbounded">
1060	<xs:element ref="gbm_pathology"/>
1061	<xs:element ref="lung_pathology"/>
1062	<xs:element ref="ovarian_pathology"/>
1063	<xs:element ref="gbm_slide"/>
1064	<xs:element ref="lung_slide"/>
1065	<xs:element ref="ovarian_slide"/>
1066	<xs:element ref="radiation_type"/>
1067	<xs:element ref="analyte_type"/>
1068	</xs:choice>
1069	<xs:attribute name="cde"/>
1070	<xs:attribute name="procurement_status"/>
1071	<xs:attribute name="xsd_ver" default="1.8"/>
1072	</xs:complexType>
1073	</xs:element>
1074	<xs:element name="gbm_pathology">
1075	<xs:complexType>
1076	<xs:sequence>
1077	<xs:element ref="histologic_type"/>
1078	<xs:element ref="histologic_nuclear_grade"/>
1079	<xs:element ref="tumor_sample_anatomic_location"/>
1080	<xs:element ref="gemistocytes_present"/>
1081	<xs:element ref="oligodendroglial_component"/>
1082	<xs:element ref="leptomeningeal_involement"/>
1083	<xs:element ref="gfap_positive"/>
1084	<xs:element ref="mib1_positive"/>
1085	</xs:sequence>
1086	</xs:complexType>
1087	</xs:element>
1088	<xs:element name="histologic_type">
1089	<xs:complexType>
1090	<xs:simpleContent>
1091	<xs:restriction base="utility:common_res_attributes">
1092	<xs:enumeration value=""/>
1093	<xs:enumeration value="ANAPLASTIC ASTROCYTOMA"/>
1094	<xs:enumeration value="GIANT CELL GLIOBLASTOMA"/>
1095	<xs:enumeration value="GLIOBLASTOMA"/>
1096	<xs:enumeration value="GLIOSARCOMA"/>
1097	<xs:enumeration value="GLIOBLASTOMA MULTIFORME"/>
1098	<xs:enumeration value="NO HISTOLOGY AVAILABLE"/>
1099	<xs:attribute name="xsd_ver" type="xs:string" default="1.8"/>
1100	</xs:restriction>
1101	</xs:simpleContent>
1102	</xs:complexType>
1103	</xs:element>
1104	<xs:element name="histologic_nuclear_grade">
1105	<xs:complexType>
1106	<xs:simpleContent>
1107	<xs:restriction base="utility:common_res_attributes">
1108	<xs:enumeration value=""/>
1109	<xs:enumeration value="LOW"/>
1110	<xs:enumeration value="HIGH"/>
1111	<xs:enumeration value="1"/>
1112	<xs:enumeration value="2"/>
1113	<xs:enumeration value="3"/>
1114	<xs:enumeration value="4"/>
1115	<xs:attribute name="cde" type="xs:string" default="2673857"/>
1116	<xs:attribute name="xsd_ver" type="xs:string" default="1.8"/>
1117	</xs:restriction>
1118	</xs:simpleContent>
1119	</xs:complexType>
1120	</xs:element>
1121	<xs:element name="tumor_sample_anatomic_location">
1122	<xs:complexType>
1123	<xs:simpleContent>
1124	<xs:restriction base="utility:common_res_attributes">
1125	<xs:enumeration value=""/>
1126	<xs:enumeration value="C70.0"/>
1127	<xs:enumeration value="C71.0"/>
1128	<xs:enumeration value="C71.1"/>
1129	<xs:enumeration value="C71.2"/>
1130	<xs:enumeration value="C71.3"/>
1131	<xs:enumeration value="C71.4"/>
1132	<xs:enumeration value="C71.5"/>
1133	<xs:enumeration value="C71.6"/>
1134	<xs:enumeration value="C71.7"/>
1135	<xs:enumeration value="C71.8"/>
1136	<xs:enumeration value="C71.9"/>
1137	<xs:enumeration value="C72.0"/>
1138	<xs:enumeration value="C72.9"/>
1139	<xs:enumeration value="C34.0"/>
1140	<xs:enumeration value="C34.1"/>
1141	<xs:enumeration value="C34.2"/>
1142	<xs:enumeration value="C34.3"/>
1143	<xs:enumeration value="C34.8"/>
1144	<xs:enumeration value="C34.9"/>
1145	<xs:enumeration value="BRAIN, NOS"/>
1146	<xs:enumeration value="BLOOD"/>
1147	<xs:enumeration value="CEREBRAL MENINGES"/>
1148	<xs:enumeration value="CEREBRUM"/>
1149	<xs:enumeration value="FRONTAL LOBE"/>
1150	<xs:enumeration value="TEMPORAL LOBE"/>
1151	<xs:enumeration value="PARIETAL LOBE"/>
1152	<xs:enumeration value="OCCIPITAL LOBE"/>
1153	<xs:enumeration value="VENTRICLE, NOS"/>
1154	<xs:enumeration value="CEREBELLUM, NOS"/>
1155	<xs:enumeration value="BRAIN STEM"/>
1156	<xs:enumeration value="OVERLAPPING LESION OF BRAIN"/>
1157	<xs:enumeration value="SPINAL CORD"/>
1158	<xs:enumeration value="NERVOUS SYSTEM, NOS"/>
1159	<xs:attribute name="cde" type="xs:string" default="2673858"/>
1160	<xs:attribute name="xsd_ver" type="xs:string" default="1.8"/>
1161	</xs:restriction>
1162	</xs:simpleContent>
1163	</xs:complexType>
1164	</xs:element>
1165	<xs:element name="gemistocytes_present">
1166	<xs:complexType>
1167	<xs:simpleContent>
1168	<xs:extension base="utility:yes_or_no">
1169	<xs:attributeGroup ref="utility:common_ext_attribute_group"/>
1170	<xs:attribute name="cde" type="xs:string" default=""/>
1171	<xs:attribute name="xsd_ver" type="xs:string" default="1.8"/>
1172	</xs:extension>
1173	</xs:simpleContent>
1174	</xs:complexType>
1175	</xs:element>
1176	<xs:element name="oligodendroglial_component">
1177	<xs:complexType>
1178	<xs:simpleContent>
1179	<xs:extension base="utility:yes_or_no">
1180	<xs:attributeGroup ref="utility:common_ext_attribute_group"/>
1181	<xs:attribute name="cde" type="xs:string" default=""/>
1182	<xs:attribute name="xsd_ver" type="xs:string" default="1.8"/>
1183	</xs:extension>
1184	</xs:simpleContent>
1185	</xs:complexType>
1186	</xs:element>
1187	<xs:element name="leptomeningeal_involement">
1188	<xs:complexType>
1189	<xs:simpleContent>
1190	<xs:extension base="utility:yes_or_no">
1191	<xs:attributeGroup ref="utility:common_ext_attribute_group"/>
1192	<xs:attribute name="cde" type="xs:string" default=""/>
1193	<xs:attribute name="xsd_ver" type="xs:string" default="1.8"/>
1194	</xs:extension>
1195	</xs:simpleContent>
1196	</xs:complexType>
1197	</xs:element>
1198	<xs:element name="gfap_positive">
1199	<xs:complexType>
1200	<xs:simpleContent>
1201	<xs:extension base="utility:yes_or_no">
1202	<xs:attributeGroup ref="utility:common_ext_attribute_group"/>
1203	<xs:attribute name="cde" type="xs:string" default=""/>
1204	<xs:attribute name="xsd_ver" type="xs:string" default="1.8"/>
1205	</xs:extension>
1206	</xs:simpleContent>
1207	</xs:complexType>
1208	</xs:element>
1209	<xs:element name="mib1_positive">
1210	<xs:complexType>
1211	<xs:simpleContent>
1212	<xs:extension base="utility:yes_or_no">
1213	<xs:attributeGroup ref="utility:common_ext_attribute_group"/>
1214	<xs:attribute name="cde" type="xs:string" default=""/>
1215	<xs:attribute name="xsd_ver" type="xs:string" default="1.8"/>
1216	</xs:extension>
1217	</xs:simpleContent>
1218	</xs:complexType>
1219	</xs:element>
1220	<xs:element name="lung_pathology">
1221	<xs:complexType>
1222	<xs:sequence>
1223	<xs:element ref="histologic_nuclear_grade"/>
1224	<xs:element ref="tumor_sample_anatomic_location"/>
1225	<xs:element ref="tumor_sample_anatomic_location"/>
1226	<xs:element ref="tnm_pathology_stage_grouping"/>
1227	<xs:element ref="tnm_pathology_tumor_status"/>
1228	<xs:element ref="tnm_pathology_lymphnode_status"/>
1229	<xs:element ref="tnm_pathology_metastatic_status"/>
1230	</xs:sequence>
1231	</xs:complexType>
1232	</xs:element>
1233	<xs:element name="tnm_pathology_stage_grouping">
1234	<xs:complexType>
1235	<xs:simpleContent>
1236	<xs:restriction base="utility:common_res_attributes">
1237	<xs:enumeration value=""/>
1238	<xs:enumeration value="0"/>
1239	<xs:enumeration value="IA"/>
1240	<xs:enumeration value="IB"/>
1241	<xs:enumeration value="IC"/>
1242	<xs:enumeration value="II"/>
1243	<xs:enumeration value="IIA"/>
1244	<xs:enumeration value="IIB"/>
1245	<xs:enumeration value="IIC"/>
1246	<xs:enumeration value="III"/>
1247	<xs:enumeration value="IIIA"/>
1248	<xs:enumeration value="IIIB"/>
1249	<xs:enumeration value="IIIC"/>
1250	<xs:enumeration value="IV"/>
1251	</xs:restriction>
1252	</xs:simpleContent>
1253	</xs:complexType>
1254	</xs:element>
1255	<xs:element name="tnm_pathology_tumor_status">
1256	<xs:complexType>
1257	<xs:simpleContent>
1258	<xs:restriction base="utility:common_res_attributes">
1259	<xs:enumeration value=""/>
1260	<xs:enumeration value="T0"/>
1261	<xs:enumeration value="T1"/>
1262	<xs:enumeration value="T1A"/>
1263	<xs:enumeration value="T1B"/>
1264	<xs:enumeration value="T1C"/>
1265	<xs:enumeration value="T2"/>
1266	<xs:enumeration value="T2A"/>
1267	<xs:enumeration value="T2B"/>
1268	<xs:enumeration value="T2C"/>
1269	<xs:enumeration value="T3"/>
1270	<xs:enumeration value="T3A"/>
1271	<xs:enumeration value="T3B"/>
1272	<xs:enumeration value="T3C"/>
1273	<xs:enumeration value="T4"/>
1274	<xs:enumeration value="TIS"/>
1275	<xs:enumeration value="TX"/>
1276	</xs:restriction>
1277	</xs:simpleContent>
1278	</xs:complexType>
1279	</xs:element>
1280	<xs:element name="tnm_pathology_lymphnode_status">
1281	<xs:complexType>
1282	<xs:simpleContent>
1283	<xs:restriction base="utility:common_res_attributes">
1284	<xs:enumeration value=""/>
1285	<xs:enumeration value="N0"/>
1286	<xs:enumeration value="N1"/>
1287	<xs:enumeration value="N2"/>
1288	<xs:enumeration value="N3"/>
1289	<xs:enumeration value="NX"/>
1290	</xs:restriction>
1291	</xs:simpleContent>
1292	</xs:complexType>
1293	</xs:element>
1294	<xs:element name="tnm_pathology_metastatic_status">
1295	<xs:complexType>
1296	<xs:simpleContent>
1297	<xs:restriction base="utility:common_res_attributes">
1298	<xs:enumeration value=""/>
1299	<xs:enumeration value="M0"/>
1300	<xs:enumeration value="M1"/>
1301	<xs:enumeration value="MX"/>
1302	</xs:restriction>
1303	</xs:simpleContent>
1304	</xs:complexType>
1305	</xs:element>
1306	<xs:element name="ovarian_pathology">
1307	<xs:complexType>
1308	<xs:sequence>
1309	<xs:element ref="histologic_nuclear_grade"/>
1310	<xs:element ref="tumor_sample_anatomic_location"/>
1311	<xs:element ref="tnm_pathology_stage_grouping"/>
1312	<xs:element ref="tnm_pathology_tumor_status"/>
1313	<xs:element ref="tnm_pathology_lymphnode_status"/>
1314	<xs:element ref="tnm_pathology_metastatic_status"/>
1315	</xs:sequence>
1316	</xs:complexType>
1317	</xs:element>
1318	<xs:element name="gbm_slide">
1319	<xs:complexType>
1320	<xs:sequence>
1321	<xs:element ref="endothelial_proliferation"/>
1322	<xs:element ref="nuclear_pleomorphism"/>
1323	<xs:element ref="palisading_necrosis"/>
1324	<xs:element ref="cellularity"/>
1325	</xs:sequence>
1326	</xs:complexType>
1327	</xs:element>
1328	<xs:element name="endothelial_proliferation">
1329	<xs:complexType>
1330	<xs:simpleContent>
1331	<xs:extension base="utility:yes_or_no">
1332	<xs:attributeGroup ref="utility:common_ext_attribute_group"/>
1333	<xs:attribute name="cde" type="xs:string" default="2841309"/>
1334	<xs:attribute name="xsd_ver" type="xs:string" default="1.8"/>
1335	</xs:extension>
1336	</xs:simpleContent>
1337	</xs:complexType>
1338	</xs:element>
1339	<xs:element name="nuclear_pleomorphism">
1340	<xs:complexType>
1341	<xs:simpleContent>
1342	<xs:extension base="utility:yes_or_no">
1343	<xs:attributeGroup ref="utility:common_ext_attribute_group"/>
1344	<xs:attribute name="cde" type="xs:string" default=""/>
1345	<xs:attribute name="xsd_ver" type="xs:string" default="1.8"/>
1346	</xs:extension>
1347	</xs:simpleContent>
1348	</xs:complexType>
1349	</xs:element>
1350	<xs:element name="palisading_necrosis">
1351	<xs:complexType>
1352	<xs:simpleContent>
1353	<xs:extension base="utility:yes_or_no">
1354	<xs:attributeGroup ref="utility:common_ext_attribute_group"/>
1355	<xs:attribute name="cde" type="xs:string" default="2841321"/>
1356	<xs:attribute name="xsd_ver" type="xs:string" default="1.8"/>
1357	</xs:extension>
1358	</xs:simpleContent>
1359	</xs:complexType>
1360	</xs:element>
1361	<xs:element name="cellularity">
1362	<xs:complexType>
1363	<xs:simpleContent>
1364	<xs:restriction base="utility:common_res_attributes">
1365	<xs:enumeration value=""/>
1366	<xs:enumeration value="LOW"/>
1367	<xs:enumeration value="MEDIUM"/>
1368	<xs:enumeration value="HIGH"/>
1369	<xs:attribute name="xsd_ver" type="xs:string" default="1.8"/>
1370	</xs:restriction>
1371	</xs:simpleContent>
1372	</xs:complexType>
1373	</xs:element>
1374	<xs:element name="lung_slide">
1375	<xs:complexType/>
1376	</xs:element>
1377	<xs:element name="ovarian_slide">
1378	<xs:complexType/>
1379	</xs:element>
1380	<xs:element name="radiation_type">
1381	<xs:complexType>
1382	<xs:simpleContent>
1383	<xs:restriction base="utility:clinical_res_attributes">
1384	<xs:enumeration value=""/>
1385	<xs:enumeration value="EXTERNAL BEAM"/>
1386	<xs:enumeration value="IMPLANTS"/>
1387	<xs:enumeration value="RADIOISOTOPES"/>
1388	<xs:enumeration value="COMBINATION"/>
1389	<xs:enumeration value="OTHER: SPECIFY IN NOTES"/>
1390	<xs:attribute name="cde" type="xs:string" default="2842944"/>
1391	<xs:attribute name="xsd_ver" type="xs:string" default="1.8"/>
1392	<xs:attribute name="tier" type="xs:string" default="2"/>
1393	</xs:restriction>
1394	</xs:simpleContent>
1395	</xs:complexType>
1396	</xs:element>
1397	<xs:element name="analyte_type">
1398	<xs:complexType>
1399	<xs:simpleContent>
1400	<xs:restriction base="utility:common_res_attributes">
1401	<xs:enumeration value=""/>
1402	<xs:enumeration value="DNA"/>
1403	<xs:enumeration value="EBV Immortalized Normal"/>
1404	<xs:enumeration value="GenomePlex (Rubicon) Amplified DNA"/>
1405	<xs:enumeration value="Repli-G (Qiagen) DNA"/>
1406	<xs:enumeration value="Repli-G X (Qiagen) DNA"/>
1407	<xs:enumeration value="RNA"/>
1408	<xs:enumeration value="Total RNA"/>
1409	<xs:attribute name="xsd_ver" type="xs:string" default="1.10"/>
1410	</xs:restriction>
1411	</xs:simpleContent>
1412	</xs:complexType>
1413	</xs:element>
1414	<xs:element name="method_of_sample_procurement">
1415	<xs:complexType mixed="true">
1416	<xs:simpleContent>
1417	<xs:restriction base="utility:common_res_attributes">
1418	<xs:attribute name="cde" type="xs:string" default="3103514"/>
1419	<xs:attribute name="xsd_ver" type="xs:string" default="2.3"/>
1420	</xs:restriction>
1421	</xs:simpleContent>
1422	</xs:complexType>
1423	</xs:element>
1424	<xs:element name="differential_report_submitted" nillable="true">
1425	<xs:complexType mixed="true">
1426	<xs:simpleContent>
1427	<xs:restriction base="utility:common_res_attributes">
1428	<xs:attribute name="cde" type="xs:string" default=""/>
1429	<xs:attribute name="xsd_ver" type="xs:string" default="2.5"/>
1430	</xs:restriction>
1431	</xs:simpleContent>
1432	</xs:complexType>
1433	</xs:element>
1434	<xs:element name="hiv_positive_status" nillable="true">
1435	<xs:complexType mixed="true">
1436	<xs:simpleContent>
1437	<xs:restriction base="utility:common_res_attributes">
1438	<xs:attribute name="cde" type="xs:string" default="2180464"/>
1439	<xs:attribute name="xsd_ver" type="xs:string" default="2.5"/>
1440	</xs:restriction>
1441	</xs:simpleContent>
1442	</xs:complexType>
1443	</xs:element>
1444	<xs:element name="b_cell_tumor_slide_submitted" nillable="true">
1445	<xs:complexType mixed="true">
1446	<xs:simpleContent>
1447	<xs:extension base="utility:yes_or_no">
1448	<xs:attributeGroup ref="utility:common_ext_attribute_group"/>
1449	<xs:attribute name="cde" type="xs:string" default="3320292"/>
1450	<xs:attribute name="xsd_ver" type="xs:string" default="2.5"/>
1451	<xs:attribute name="tier" type="xs:string" default="2"/>
1452	</xs:extension>
1453	</xs:simpleContent>
1454	</xs:complexType>
1455	</xs:element>
1456	<xs:element name="t_cell_tumor_slide_submitted" nillable="true">
1457	<xs:complexType mixed="true">
1458	<xs:simpleContent>
1459	<xs:extension base="utility:yes_or_no">
1460	<xs:attributeGroup ref="utility:common_ext_attribute_group"/>
1461	<xs:attribute name="cde" type="xs:string" default="3320295"/>
1462	<xs:attribute name="xsd_ver" type="xs:string" default="2.5"/>
1463	<xs:attribute name="tier" type="xs:string" default="2"/>
1464	</xs:extension>
1465	</xs:simpleContent>
1466	</xs:complexType>
1467	</xs:element>
1468	<xs:element name="submitted_for_lce">
1469	<xs:complexType>
1470	<xs:simpleContent>
1471	<xs:extension base="utility:yes_or_no">
1472	<xs:attributeGroup ref="utility:common_ext_attribute_group"/>
1473	<xs:attribute name="cde" type="xs:string" default="3288488"/>
1474	<xs:attribute name="xsd_ver" type="xs:string" default="1.8"/>
1475	</xs:extension>
1476	</xs:simpleContent>
1477	</xs:complexType>
1478	</xs:element>
1479	<xs:element name="maximum_tumor_dimension" nillable="true">
1480	<xs:complexType mixed="true">
1481	<xs:simpleContent>
1482	<xs:restriction base="utility:common_res_attributes">
1483	<xs:attribute name="cde" type="xs:string" default="64215"/>
1484	<xs:attribute name="xsd_ver" type="xs:string" default="2.5"/>
1485	</xs:restriction>
1486	</xs:simpleContent>
1487	</xs:complexType>
1488	</xs:element>
1489	<xs:element name="h_and_e_tumor_slide_submitted" default="" nillable="true">
1490	<xs:complexType mixed="true">
1491	<xs:simpleContent>
1492	<xs:extension base="utility:yes_or_no">
1493	<xs:attributeGroup ref="utility:common_ext_attribute_group"/>
1494	<xs:attribute name="cde" type="xs:string" default="3081944"/>
1495	<xs:attribute name="xsd_ver" type="xs:string" default="2.5"/>
1496	<xs:attribute name="tier" type="xs:string" default="2"/>
1497	</xs:extension>
1498	</xs:simpleContent>
1499	</xs:complexType>
1500	</xs:element>
1501	<xs:element name="reason_path_confirm_diagnosis_not_matching" nillable="true">
1502	<xs:complexType>
1503	<xs:simpleContent>
1504	<xs:extension base="xs:string">
1505	<xs:attributeGroup ref="utility:common_ext_attribute_group"/>
1506	<xs:attribute name="cde" type="xs:string" default="3288315"/>
1507	<xs:attribute name="xsd_ver" type="xs:string" default="2.5"/>
1508	</xs:extension>
1509	</xs:simpleContent>
1510	</xs:complexType>
1511	</xs:element>
1512	<xs:element name="days_to_sample_procurement" default="" nillable="true">
1513	<xs:complexType mixed="true">
1514	<xs:simpleContent>
1515	<xs:restriction base="utility:common_res_attributes">
1516	<xs:attribute name="cde" type="xs:string" default="3288495"/>
1517	<xs:attribute name="xsd_ver" type="xs:string" default="2.5"/>
1518	</xs:restriction>
1519	</xs:simpleContent>
1520	</xs:complexType>
1521	</xs:element>
1522	<xs:element name="days_to_normal_sample_procurement" default="" nillable="true">
1523	<xs:complexType mixed="true">
1524	<xs:simpleContent>
1525	<xs:restriction base="utility:common_res_attributes">
1526	<xs:attribute name="cde" type="xs:string" default="3288496"/>
1527	<xs:attribute name="xsd_ver" type="xs:string" default="2.5"/>
1528	</xs:restriction>
1529	</xs:simpleContent>
1530	</xs:complexType>
1531	</xs:element>
1532	<xs:element name="days_to_pathology_review" default="" nillable="true">
1533	<xs:complexType mixed="true">
1534	<xs:simpleContent>
1535	<xs:restriction base="utility:common_res_attributes">
1536	<xs:attribute name="cde" type="xs:string" default="3288497"/>
1537	<xs:attribute name="xsd_ver" type="xs:string" default="2.5"/>
1538	</xs:restriction>
1539	</xs:simpleContent>
1540	</xs:complexType>
1541	</xs:element>
1542	</xs:schema>

   
File: TCGA_BCR.GBM_Clinical.xsd  

3	<xs:schema elementFormDefault="qualified" version="2.5.0"	<>	4	<xs:schema elementFormDefault="qualified" version="2.4.4"
5	xmlns:utility="http://tcga.nci/bcr/xml/utility/2.5"	<>	6	xmlns:utility="http://tcga.nci/bcr/xml/utility/2.4"
6	xmlns:admin="http://tcga.nci/bcr/xml/administration/2.5"		7	xmlns:admin="http://tcga.nci/bcr/xml/administration/2.4"
7	xmlns:shared="http://tcga.nci/bcr/xml/clinical/shared/2.5"		8	xmlns:shared="http://tcga.nci/bcr/xml/clinical/shared/2.4"
8	xmlns:rad="http://tcga.nci/bcr/xml/clinical/radiation/2.5"		9	xmlns:rad="http://tcga.nci/bcr/xml/clinical/radiation/2.4"
9	xmlns:rx="http://tcga.nci/bcr/xml/clinical/pharmaceutical/2.5"		10	xmlns:rx="http://tcga.nci/bcr/xml/clinical/pharmaceutical/2.4"
10	xmlns:follow_up_v1.0="http://tcga.nci/bcr/xml/clinical/gbm/followup/2.5/1.0"
11	xmlns="http://tcga.nci/bcr/xml/clinical/gbm/2.5"		11	xmlns="http://tcga.nci/bcr/xml/clinical/gbm/2.4"
12	targetNamespace="http://tcga.nci/bcr/xml/clinical/gbm/2.5"		12	targetNamespace="http://tcga.nci/bcr/xml/clinical/gbm/2.4"
28	<xs:import namespace="http://tcga.nci/bcr/xml/utility/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/utility/2.5/TCGA_BCR.Utility.xsd" />	<>	28	<xs:import namespace="http://tcga.nci/bcr/xml/utility/2.4" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/utility/2.4/TCGA_BCR.Utility.xsd" />
29	<xs:import namespace="http://tcga.nci/bcr/xml/administration/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/administration/2.5/TCGA_BCR.Administration.xsd" />		29	<xs:import namespace="http://tcga.nci/bcr/xml/administration/2.4" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/administration/2.4/TCGA_BCR.Administration.xsd" />
30	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/shared/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/shared/2.5/TCGA_BCR.Shared_Clinical_Elements.xsd" />		30	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/shared/2.4" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/shared/2.4/TCGA_BCR.Shared_Clinical_Elements.xsd" />
31	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/radiation/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/radiation/2.5/TCGA_BCR.Radiation.xsd" />		31	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/radiation/2.4" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/radiation/2.4/TCGA_BCR.Radiation.xsd" />
32	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/pharmaceutical/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/pharmaceutical/2.5/TCGA_BCR.Pharmaceutical.xsd" />		32	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/pharmaceutical/2.4" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/pharmaceutical/2.4/TCGA_BCR.Pharmaceutical.xsd" />
33	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/gbm/followup/2.5/1.0" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/gbm/followup/2.5/TCGA_BCR.GBM_Clinical_FollowUp_v1.0.xsd" />
42	<xs:attribute name="schemaVersion" type="xs:decimal" use="required" fixed="2.5"/>	<>	41	<xs:attribute name="schemaVersion" type="xs:decimal" use="required" fixed="2.4"/>
50	<xs:element ref="shared:tumor_histologic_subtype" />	<>	49	<xs:element ref="histological_type" />
		-+	89	<xs:element ref="shared:pretreatment_history" />
			90	<xs:element ref="radiation_therapy" />
		<>	109	<xs:element ref="shared:chemo_therapy" />
			110	<xs:element ref="shared:immuno_therapy" />
			111	<xs:element ref="shared:hormonal_therapy" />
98	<xs:element ref="shared:person_neoplasm_cancer_status" />		112	<xs:element ref="shared:targeted_molecular_therapy" />
101	<xs:element ref="shared:day_of_form_completion" />	<>	116	<xs:element ref="shared:day_of_tumor_progression" />
102	<xs:element ref="shared:month_of_form_completion" />		117	<xs:element ref="shared:month_of_tumor_progression" />
103	<xs:element ref="shared:year_of_form_completion" />		118	<xs:element ref="shared:year_of_tumor_progression" />
105	<xs:element ref="shared:days_to_form_completion" />	<>	121	<xs:element ref="shared:days_to_tumor_progression" />
		-+	124	<xs:choice>
			125	<xs:sequence>
			126	<xs:element ref="shared:day_of_tumor_recurrence" />
			127	<xs:element ref="shared:month_of_tumor_recurrence" />
			128	<xs:element ref="shared:year_of_tumor_recurrence" />
			129	</xs:sequence>
		-+	131	<xs:element ref="shared:days_to_tumor_recurrence" />
			132	</xs:choice>
109	<xs:element ref="shared:pretreatment_history" />	<>	135	<xs:element ref="shared:additional_radiation_therapy" />
110	<xs:element ref="shared:initial_pathologic_diagnosis_method" />		136	<xs:element ref="additional_chemo_therapy" />
111	<xs:element ref="shared:anatomic_organ_subdivision" />		137	<xs:element ref="additional_immuno_therapy" />
114	<xs:element ref="shared:karnofsky_performance_score" />	<>	138	<xs:element ref="shared:additional_pharmaceutical_therapy" />
115	<xs:element ref="shared:eastern_cancer_oncology_group" />		139	<xs:element ref="additional_drug_therapy" />
			140	<xs:element ref="anatomic_organ_subdivision" />
			141	<xs:element ref="initial_pathologic_diagnosis_method" />
116	<xs:element ref="shared:performance_status_scale_timing" />		142	<xs:element ref="shared:person_neoplasm_cancer_status" />
117	<xs:element ref="rx:drugs" />		143	<xs:element ref="drugs" />
118	<xs:element ref="rad:radiations" />		144	<xs:element ref="radiations" />
120	<xs:element name="follow_ups">	<>	145	<xs:element ref="examinations" />
121	<xs:annotation>
122	<xs:documentation>We are using namespaces and version numbers to distinguish one version of followup from another.</xs:documentation>
123	</xs:annotation>
124	<xs:complexType>
125	<xs:sequence>		146	<xs:element ref="surgeries" />
126	<xs:element ref="follow_up_v1.0:follow_up_v1.0" minOccurs="0" maxOccurs="unbounded" />
		<>	151	<xs:element name="histological_type" nillable="true">
			152	<xs:complexType mixed="true">
			153	<xs:simpleContent>
			154	<xs:restriction base="utility:clinical_res_attributes">
			155	<xs:attribute name="cde" type="xs:string" default="2831122" />
			156	<xs:attribute name="xsd_ver" type="xs:string" default="1.9" />
			157	<xs:attribute name="tier" type="xs:string" default="1" />
130	</xs:sequence>		158	</xs:restriction>
			159	</xs:simpleContent>
		-+	176	<xs:element name="additional_chemo_therapy" nillable="true">
			177	<xs:complexType>
			178	<xs:simpleContent>
			179	<xs:extension base="utility:yes_or_no">
			180	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			181	<xs:attribute name="cde" type="xs:string" default="2650626" />
			182	<xs:attribute name="xsd_ver" type="xs:string" default="1.9" />
			183	<xs:attribute name="tier" type="xs:string" default="2" />
			184	</xs:extension>
			185	</xs:simpleContent>
			186	</xs:complexType>
			187	</xs:element>
		-+	189	<xs:element name="additional_immuno_therapy" nillable="true">
			190	<xs:complexType>
			191	<xs:simpleContent>
			192	<xs:extension base="utility:yes_or_no">
			193	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			194	<xs:attribute name="cde" type="xs:string" default="2759828" />
			195	<xs:attribute name="xsd_ver" type="xs:string" default="1.9" />
			196	<xs:attribute name="tier" type="xs:string" default="2" />
			197	</xs:extension>
			198	</xs:simpleContent>
			199	</xs:complexType>
			200	</xs:element>
		-+	202	<xs:element name="additional_drug_therapy" nillable="true">
			203	<xs:complexType>
			204	<xs:simpleContent>
			205	<xs:extension base="utility:yes_or_no">
			206	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			207	<xs:attribute name="cde" type="xs:string" default="2786150" />
			208	<xs:attribute name="xsd_ver" type="xs:string" default="1.9" />
			209	<xs:attribute name="tier" type="xs:string" default="2" />
			210	</xs:extension>
			211	</xs:simpleContent>
			212	</xs:complexType>
			213	</xs:element>
		-+	215	<xs:element name="anatomic_organ_subdivision" nillable="true">
			216	<xs:complexType mixed="true">
			217	<xs:simpleContent>
			218	<xs:restriction base="utility:clinical_res_attributes">
			219	<xs:attribute name="cde" type="xs:string" default="2008006" />
			220	<xs:attribute name="xsd_ver" type="xs:string" default="1.9" />
			221	<xs:attribute name="tier" type="xs:string" default="2" />
			222	</xs:restriction>
			223	</xs:simpleContent>
			224	</xs:complexType>
			225	</xs:element>
		-+	227	<xs:element name="initial_pathologic_diagnosis_method" nillable="true">
			228	<xs:complexType>
			229	<xs:simpleContent>
			230	<xs:restriction base="utility:clinical_res_attributes">
			231	<xs:enumeration value="" />
			232	<xs:enumeration value="CYTOLOGY" />
			233	<xs:enumeration value="FINE NEEDLE ASPIRATION BIOPSY" />
			234	<xs:enumeration value="INCISION BIOPSY" />
			235	<xs:enumeration value="EXCISIONAL BIOPSY" />
			236	<xs:enumeration value="TUMOR RESECTION" />
			237	<xs:enumeration value="OTHER METHOD, SPECIFY IN NOTES" />
			238	<xs:attribute name="cde" type="xs:string" default="2757941" />
			239	<xs:attribute name="xsd_ver" type="xs:string" default="1.9" />
			240	<xs:attribute name="tier" type="xs:string" default="2" />
			241	</xs:restriction>
			242	</xs:simpleContent>
			243	</xs:complexType>
			244	</xs:element>
		-+	246	<xs:element name="radiation_therapy">
			247	<xs:complexType>
			248	<xs:simpleContent>
			249	<xs:extension base="utility:yes_or_no">
			250	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			251	<xs:attribute name="cde" type="xs:string" default="2005312" />
			252	<xs:attribute name="xsd_ver" type="xs:string" default="1.9" />
			253	<xs:attribute name="tier" type="xs:string" default="1" />
			254	</xs:extension>
			255	</xs:simpleContent>
			256	</xs:complexType>
			257	</xs:element>
		-+	259	<xs:element name="drugs">
			260	<xs:complexType>
			261	<xs:sequence minOccurs="0" maxOccurs="unbounded">
			262	<xs:element ref="drug" />
			263	</xs:sequence>
			264	</xs:complexType>
			265	</xs:element>
		-+	267	<xs:element name="drug">
			268	<xs:complexType>
			269	<xs:sequence>
			270	<xs:element ref="rx:bcr_drug_barcode" />
			271	<xs:element ref="rx:bcr_drug_uuid" />
			272	<xs:element ref="rx:drug_category" />
			273	<xs:element ref="rx:total_dose" />
			274	<xs:element ref="rx:total_dose_units" />
			275	<xs:element ref="rx:number_cycles" />
		-+	277	<xs:choice>
			278	<xs:sequence>
			279	<xs:element ref="rx:day_of_drug_therapy_start" />
			280	<xs:element ref="rx:month_of_drug_therapy_start" />
			281	<xs:element ref="rx:year_of_drug_therapy_start" />
			282	</xs:sequence>
			283	<xs:element ref="rx:days_to_drug_therapy_start" />
			284	</xs:choice>
		-+	286	<xs:choice>
			287	<xs:sequence>
			288	<xs:element ref="rx:day_of_drug_therapy_end" />
			289	<xs:element ref="rx:month_of_drug_therapy_end" />
			290	<xs:element ref="rx:year_of_drug_therapy_end" />
			291	</xs:sequence>
			292	<xs:element ref="rx:days_to_drug_therapy_end" />
			293	</xs:choice>
		-+	295	<xs:element ref="initial_course" />
			296	<xs:element ref="rx:drug_name" />
			297	<xs:element ref="shared:regimen_indication" />
			298	<xs:element ref="shared:regimen_indication_notes" />
			299	<xs:element ref="route_of_administration" />
			300	<xs:element ref="route_of_administration_notes" />
			301	<xs:element ref="rx:therapy_ongoing" />
			302	</xs:sequence>
			303	</xs:complexType>
			304	</xs:element>
		-+	306	<xs:element name="bcr_drug_barcode">
			307	<xs:complexType>
			308	<xs:simpleContent>
			309	<xs:extension base="xs:NCName">
			310	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			311	<xs:attribute name="xsd_ver" type="xs:string" default="1.15" />
			312	</xs:extension>
			313	</xs:simpleContent>
			314	</xs:complexType>
			315	</xs:element>
		-+	317	<xs:element name="number_cycles">
			318	<xs:complexType>
			319	<xs:simpleContent>
			320	<xs:extension base="xs:string">
			321	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			322	<xs:attribute name="cde" type="xs:string" default="62590" />
			323	<xs:attribute name="xsd_ver" type="xs:string" default="1.8" />
			324	<xs:attribute name="tier" type="xs:string" default="2" />
			325	</xs:extension>
			326	</xs:simpleContent>
			327	</xs:complexType>
			328	</xs:element>
		-+	330	<xs:element name="drug_category">
			331	<xs:complexType>
			332	<xs:simpleContent>
			333	<xs:restriction base="utility:clinical_res_attributes">
			334	<xs:enumeration value="" />
			335	<xs:enumeration value="CHEMO" />
			336	<xs:enumeration value="HORMONAL" />
			337	<xs:enumeration value="IMMUNO" />
			338	<xs:enumeration value="TARGETED" />
			339	<xs:attribute name="cde" type="xs:string" default="729" />
			340	<xs:attribute name="xsd_ver" type="xs:string" default="1.8" />
			341	<xs:attribute name="tier" type="xs:string" default="2" />
			342	</xs:restriction>
			343	</xs:simpleContent>
			344	</xs:complexType>
			345	</xs:element>
		-+	347	<xs:element name="initial_course">
			348	<xs:complexType>
			349	<xs:simpleContent>
			350	<xs:extension base="utility:yes_or_no">
			351	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			352	<xs:attribute name="cde" type="xs:string" default="2003586" />
			353	<xs:attribute name="xsd_ver" type="xs:string" default="1.8" />
			354	<xs:attribute name="tier" type="xs:string" default="2" />
			355	</xs:extension>
			356	</xs:simpleContent>
			357	</xs:complexType>
			358	</xs:element>
		-+	360	<xs:element name="route_of_administration">
			361	<xs:complexType>
			362	<xs:simpleContent>
			363	<xs:restriction base="utility:clinical_res_attributes">
			364	<xs:enumeration value="" />
			365	<xs:enumeration value="ORAL" />
			366	<xs:enumeration value="INTRAVENOUS (IV)" />
			367	<xs:enumeration value="INTRATUMORAL" />
			368	<xs:enumeration value="INTRA-PERITONEAL (IP)" />
			369	<xs:enumeration value="IV AND IP" />
			370	<xs:enumeration value="OTHER: SPECIFY IN NOTES" />
			371	<xs:attribute name="cde" type="xs:string" default="2003586" />
			372	<xs:attribute name="xsd_ver" type="xs:string" default="1.12" />
			373	<xs:attribute name="tier" type="xs:string" default="2" />
			374	</xs:restriction>
			375	</xs:simpleContent>
			376	</xs:complexType>
			377	</xs:element>
		-+	379	<xs:element name="route_of_administration_notes">
			380	<xs:complexType mixed="true">
			381	<xs:simpleContent>
			382	<xs:restriction base="utility:clinical_res_attributes">
			383	<xs:attribute name="cde" type="xs:string" default="2190504" />
			384	<xs:attribute name="xsd_ver" type="xs:string" default="1.12" />
			385	<xs:attribute name="tier" type="xs:string" default="2" />
			386	</xs:restriction>
			387	</xs:simpleContent>
			388	</xs:complexType>
			389	</xs:element>
		-+	391	<xs:element name="radiations">
			392	<xs:complexType>
			393	<xs:sequence minOccurs="0" maxOccurs="unbounded">
			394	<xs:element ref="radiation" />
			395	</xs:sequence>
			396	</xs:complexType>
			397	</xs:element>
		-+	399	<xs:element name="radiation">
			400	<xs:complexType>
			401	<xs:sequence>
			402	<xs:element ref="rad:bcr_radiation_barcode" />
			403	<xs:element ref="rad:bcr_radiation_uuid"/>
		-+	405	<xs:choice>
			406	<xs:sequence>
			407	<xs:element ref="rad:day_of_radiation_therapy_start" />
			408	<xs:element ref="rad:month_of_radiation_therapy_start" />
			409	<xs:element ref="rad:year_of_radiation_therapy_start" />
			410	</xs:sequence>
			411	<xs:element ref="rad:days_to_radiation_therapy_start" />
			412	</xs:choice>
		-+	414	<xs:choice>
			415	<xs:sequence>
			416	<xs:element ref="rad:day_of_radiation_therapy_end" />
			417	<xs:element ref="rad:month_of_radiation_therapy_end" />
			418	<xs:element ref="rad:year_of_radiation_therapy_end" />
			419	</xs:sequence>
			420	<xs:element ref="rad:days_to_radiation_therapy_end" />
			421	</xs:choice>
		-+	423	<xs:element ref="rad:radiation_type" />
			424	<xs:element ref="rad:radiation_type_notes" />
			425	<xs:element ref="rad:radiation_dosage" />
			426	<xs:element ref="rad:units" />
			427	<xs:element ref="rad:numfractions" />
			428	<xs:element ref="anatomic_treatment_site" />
			429	<xs:element ref="shared:regimen_indication" />
			430	<xs:element ref="shared:regimen_indication_notes" />
			431	<xs:element ref="rad:radiation_treatment_ongoing" />
			432	</xs:sequence>
			433	</xs:complexType>
			434	</xs:element>
		-+	436	<xs:element name="bcr_radiation_barcode">
			437	<xs:complexType>
			438	<xs:simpleContent>
			439	<xs:extension base="xs:NCName">
			440	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			441	<xs:attribute name="xsd_ver" type="xs:string" default="1.15" />
			442	</xs:extension>
			443	</xs:simpleContent>
			444	</xs:complexType>
			445	</xs:element>
		-+	447	<xs:element name="radiation_treatment_ongoing" nillable="true">
			448	<xs:complexType>
			449	<xs:simpleContent>
			450	<xs:extension base="utility:yes_or_no">
			451	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			452	<xs:attribute name="cde" type="xs:string" default="2842745" />
			453	<xs:attribute name="xsd_ver" type="xs:string" default="1.12" />
			454	<xs:attribute name="tier" type="xs:string" default="2" />
			455	</xs:extension>
			456	</xs:simpleContent>
			457	</xs:complexType>
			458	</xs:element>
		-+	460	<xs:element name="anatomic_treatment_site">
			461	<xs:complexType>
			462	<xs:simpleContent>
			463	<xs:extension base="xs:string">
			464	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			465	<xs:attribute name="cde" type="xs:string" default="2793522" />
			466	<xs:attribute name="xsd_ver" type="xs:string" default="1.8" />
			467	<xs:attribute name="tier" type="xs:string" default="2" />
			468	</xs:extension>
			469	</xs:simpleContent>
			470	</xs:complexType>
			471	</xs:element>
		-+	473	<xs:element name="examinations">
			474	<xs:complexType>
			475	<xs:sequence minOccurs="0" maxOccurs="unbounded">
			476	<xs:element ref="examination" />
			477	</xs:sequence>
			478	</xs:complexType>
			479	</xs:element>
		-+	481	<xs:element name="examination">
			482	<xs:complexType>
			483	<xs:sequence>
			484	<xs:element ref="bcr_examination_barcode" />
			485	<xs:element ref="karnofsky_performance_score" />
			486	<xs:element ref="eastern_cancer_oncology_group" />
			487	<xs:element ref="progression_status" />
			488	<xs:element ref="shared:performance_status_scale_timing" />
			489	<xs:element ref="shared:progression_determined_by" />
			490	<xs:element ref="shared:progression_determined_by_notes" />
			491	</xs:sequence>
			492	</xs:complexType>
			493	</xs:element>
		-+	495	<xs:element name="bcr_examination_barcode">
			496	<xs:complexType>
			497	<xs:simpleContent>
			498	<xs:extension base="xs:NCName">
			499	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			500	<xs:attribute name="xsd_ver" type="xs:string" default="1.15" />
			501	</xs:extension>
			502	</xs:simpleContent>
			503	</xs:complexType>
			504	</xs:element>
		-+	506	<xs:element name="karnofsky_performance_score">
			507	<xs:complexType>
			508	<xs:simpleContent>
			509	<xs:restriction base="utility:clinical_res_attributes">
			510	<xs:enumeration value="" />
			511	<xs:enumeration value="0" />
			512	<xs:enumeration value="10" />
			513	<xs:enumeration value="20" />
			514	<xs:enumeration value="30" />
			515	<xs:enumeration value="40" />
			516	<xs:enumeration value="50" />
			517	<xs:enumeration value="60" />
			518	<xs:enumeration value="70" />
			519	<xs:enumeration value="80" />
			520	<xs:enumeration value="90" />
			521	<xs:enumeration value="100" />
			522	<xs:attribute name="cde" type="xs:string" default="2003853" />
			523	<xs:attribute name="xsd_ver" type="xs:string" default="1.8" />
			524	<xs:attribute name="tier" type="xs:string" default="2" />
			525	</xs:restriction>
			526	</xs:simpleContent>
			527	</xs:complexType>
			528	</xs:element>
		-+	530	<xs:element name="eastern_cancer_oncology_group">
			531	<xs:complexType>
			532	<xs:simpleContent>
			533	<xs:restriction base="utility:clinical_res_attributes">
			534	<xs:enumeration value="" />
			535	<xs:enumeration value="0" />
			536	<xs:enumeration value="1" />
			537	<xs:enumeration value="2" />
			538	<xs:enumeration value="3" />
			539	<xs:enumeration value="4" />
			540	<xs:enumeration value="5" />
			541	<xs:attribute name="cde" type="xs:string" default="88" />
			542	<xs:attribute name="xsd_ver" type="xs:string" default="1.9" />
			543	<xs:attribute name="tier" type="xs:string" default="2" />
			544	</xs:restriction>
			545	</xs:simpleContent>
			546	</xs:complexType>
			547	</xs:element>
		-+	549	<xs:element name="progression_status">
			550	<xs:complexType>
			551	<xs:simpleContent>
			552	<xs:extension base="utility:yes_or_no">
			553	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			554	<xs:attribute name="cde" type="xs:string" default="2673787" />
			555	<xs:attribute name="xsd_ver" type="xs:string" default="1.8" />
			556	<xs:attribute name="tier" type="xs:string" default="2" />
			557	</xs:extension>
			558	</xs:simpleContent>
			559	</xs:complexType>
			560	</xs:element>
		-+	562	<xs:element name="performance_status_scale_timing">
			563	<xs:complexType>
			564	<xs:simpleContent>
			565	<xs:restriction base="utility:clinical_res_attributes">
			566	<xs:enumeration value="" />
			567	<xs:enumeration value="PREOPERATIVE" />
			568	<xs:enumeration value="PRE-ADJUVANT THERAPY" />
			569	<xs:enumeration value="POST-ADJUVANT THERAPY" />
			570	<xs:enumeration value="OTHER" />
			571	<xs:attribute name="cde" type="xs:string" default="2792763" />
			572	<xs:attribute name="xsd_ver" type="xs:string" default="1.9" />
			573	<xs:attribute name="tier" type="xs:string" default="2" />
			574	</xs:restriction>
			575	</xs:simpleContent>
			576	</xs:complexType>
			577	</xs:element>
		-+	579	<xs:element name="progression_determined_by">
			580	<xs:complexType>
			581	<xs:simpleContent>
			582	<xs:restriction base="utility:clinical_res_attributes">
			583	<xs:enumeration value="" />
			584	<xs:enumeration value="LABORATORY" />
			585	<xs:enumeration value="PATHOLOGY" />
			586	<xs:enumeration value="RADIATION" />
			587	<xs:enumeration value="PHYSICAL EXAMINATION" />
			588	<xs:enumeration value="IMAGING STUDY" />
			589	<xs:enumeration value="MOLECULAR MARKER(S)" />
			590	<xs:enumeration value="FIRST SEEN AT FURTHER SURGERY" />
			591	<xs:enumeration value="OTHER METHOD: SPECIFY IN NOTES" />
			592	<xs:attribute name="cde" type="xs:string" default="2786205" />
			593	<xs:attribute name="xsd_ver" type="xs:string" default="1.9" />
			594	<xs:attribute name="tier" type="xs:string" default="2" />
			595	</xs:restriction>
			596	</xs:simpleContent>
			597	</xs:complexType>
			598	</xs:element>
		-+	600	<xs:element name="progression_determined_by_notes">
			601	<xs:complexType mixed="true">
			602	<xs:simpleContent>
			603	<xs:restriction base="utility:clinical_res_attributes">
			604	<xs:attribute name="cde" type="xs:string" default="2786210" />
			605	<xs:attribute name="xsd_ver" type="xs:string" default="1.9" />
			606	<xs:attribute name="tier" type="xs:string" default="2" />
			607	</xs:restriction>
			608	</xs:simpleContent>
			609	</xs:complexType>
			610	</xs:element>
		-+	612	<xs:element name="surgeries">
			613	<xs:complexType>
			614	<xs:sequence minOccurs="0" maxOccurs="unbounded">
			615	<xs:element ref="surgery" />
			616	</xs:sequence>
			617	</xs:complexType>
			618	</xs:element>
		-+	620	<xs:element name="surgery">
			621	<xs:complexType>
			622	<xs:sequence>
			623	<xs:element ref="bcr_surgery_barcode" />
		-+	625	<xs:choice>
			626	<xs:sequence>
			627	<xs:element ref="day_of_procedure" />
			628	<xs:element ref="month_of_procedure" />
			629	<xs:element ref="year_of_procedure" />
			630	</xs:sequence>
			631	<xs:element ref="days_to_procedure" />
			632	</xs:choice>
		-+	634	<xs:element ref="procedure_type" />
			635	</xs:sequence>
			636	</xs:complexType>
			637	</xs:element>
		-+	639	<xs:element name="bcr_surgery_barcode">
			640	<xs:complexType>
			641	<xs:simpleContent>
			642	<xs:extension base="xs:NCName">
			643	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			644	<xs:attribute name="cde" type="xs:string" default="2003586" />
			645	<xs:attribute name="xsd_ver" type="xs:string" default="1.8" />
			646	</xs:extension>
			647	</xs:simpleContent>
			648	</xs:complexType>
			649	</xs:element>
		-+	651	<xs:element name="day_of_procedure">
			652	<xs:complexType mixed="true">
			653	<xs:simpleContent>
			654	<xs:restriction base="utility:clinical_res_attributes">
			655	<xs:attribute name="cde" type="xs:string" default="2896965" />
			656	<xs:attribute name="xsd_ver" type="xs:string" default="1.12" />
			657	<xs:attribute name="tier" type="xs:string" default="1" />
			658	</xs:restriction>
			659	</xs:simpleContent>
			660	</xs:complexType>
			661	</xs:element>
		-+	663	<xs:element name="month_of_procedure">
			664	<xs:complexType mixed="true">
			665	<xs:simpleContent>
			666	<xs:restriction base="utility:clinical_res_attributes">
			667	<xs:attribute name="cde" type="xs:string" default="2896963" />
			668	<xs:attribute name="xsd_ver" type="xs:string" default="1.12" />
			669	<xs:attribute name="tier" type="xs:string" default="1" />
			670	</xs:restriction>
			671	</xs:simpleContent>
			672	</xs:complexType>
			673	</xs:element>
		-+	675	<xs:element name="year_of_procedure">
			676	<xs:complexType mixed="true">
			677	<xs:simpleContent>
			678	<xs:restriction base="utility:clinical_res_attributes">
			679	<xs:attribute name="cde" type="xs:string" default="2896985" />
			680	<xs:attribute name="xsd_ver" type="xs:string" default="1.12" />
			681	<xs:attribute name="tier" type="xs:string" default="1" />
			682	</xs:restriction>
			683	</xs:simpleContent>
			684	</xs:complexType>
			685	</xs:element>
		-+	687	<xs:element name="procedure_type">
			688	<xs:complexType mixed="true">
			689	<xs:simpleContent>
			690	<xs:restriction base="utility:clinical_res_attributes">
			691	<xs:attribute name="cde" type="xs:string" default="2199761" />
			692	<xs:attribute name="xsd_ver" type="xs:string" default="1.9" />
			693	<xs:attribute name="tier" type="xs:string" default="2" />
			694	</xs:restriction>
			695	</xs:simpleContent>
			696	</xs:complexType>
			697	</xs:element>
		-+	699	<xs:element name="days_to_drug_treatment_start">
			700	<xs:complexType mixed="true">
			701	<xs:simpleContent>
			702	<xs:restriction base="utility:clinical_res_attributes">
			703	<xs:attribute name="cde" type="xs:string" default="" />
			704	<xs:attribute name="xsd_ver" type="xs:string" default="" />
			705	<xs:attribute name="tier" type="xs:string" default="1" />
			706	</xs:restriction>
			707	</xs:simpleContent>
			708	</xs:complexType>
			709	</xs:element>
		-+	711	<xs:element name="days_to_drug_treatment_end">
			712	<xs:complexType mixed="true">
			713	<xs:simpleContent>
			714	<xs:restriction base="utility:clinical_res_attributes">
			715	<xs:attribute name="cde" type="xs:string" default="" />
			716	<xs:attribute name="xsd_ver" type="xs:string" default="" />
			717	<xs:attribute name="tier" type="xs:string" default="1" />
			718	</xs:restriction>
			719	</xs:simpleContent>
			720	</xs:complexType>
			721	</xs:element>
		-+	723	<xs:element name="days_to_radiation_treatment_start">
			724	<xs:complexType mixed="true">
			725	<xs:simpleContent>
			726	<xs:restriction base="utility:clinical_res_attributes">
			727	<xs:attribute name="cde" type="xs:string" default="" />
			728	<xs:attribute name="xsd_ver" type="xs:string" default="" />
			729	<xs:attribute name="tier" type="xs:string" default="1" />
			730	</xs:restriction>
			731	</xs:simpleContent>
			732	</xs:complexType>
			733	</xs:element>
		-+	735	<xs:element name="days_to_radiation_treatment_end">
			736	<xs:complexType mixed="true">
			737	<xs:simpleContent>
			738	<xs:restriction base="utility:clinical_res_attributes">
			739	<xs:attribute name="cde" type="xs:string" default="" />
			740	<xs:attribute name="xsd_ver" type="xs:string" default="" />
			741	<xs:attribute name="tier" type="xs:string" default="1" />
			742	</xs:restriction>
			743	</xs:simpleContent>
			744	</xs:complexType>
			745	</xs:element>
		-+	747	<xs:element name="days_to_procedure">
			748	<xs:complexType mixed="true">
			749	<xs:simpleContent>
			750	<xs:restriction base="utility:clinical_res_attributes">
			751	<xs:attribute name="cde" type="xs:string" default="" />
			752	<xs:attribute name="xsd_ver" type="xs:string" default="" />
			753	<xs:attribute name="tier" type="xs:string" default="1" />
			754	</xs:restriction>
			755	</xs:simpleContent>
			756	</xs:complexType>
			757	</xs:element>

   
File: TCGA_BCR.GBM_Clinical_FollowUp_v1.0.xsd  

1	<?xml version="1.0" encoding="utf-8" ?>	+-
4	<xs:schema elementFormDefault="qualified" version="2.5.0"	+-
5	xmlns:xs="http://www.w3.org/2001/XMLSchema"
6	xmlns:shared="http://tcga.nci/bcr/xml/clinical/shared/2.5"
7	xmlns:utility="http://tcga.nci/bcr/xml/utility/2.5"
8	xmlns:admin="http://tcga.nci/bcr/xml/administration/2.5"
9	xmlns="http://tcga.nci/bcr/xml/clinical/gbm/followup/2.5/1.0"
10	targetNamespace="http://tcga.nci/bcr/xml/clinical/gbm/followup/2.5/1.0"
11	xmlns:jaxb="http://java.sun.com/xml/ns/jaxb" jaxb:version="1.0" >
13	<xs:import schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/utility/2.5/TCGA_BCR.Utility.xsd" namespace="http://tcga.nci/bcr/xml/utility/2.5" />	+-
14	<xs:import schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/administration/2.5/TCGA_BCR.Administration.xsd" namespace="http://tcga.nci/bcr/xml/administration/2.5" />
15	<xs:import schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/shared/2.5/TCGA_BCR.Shared_Clinical_Elements.xsd" namespace="http://tcga.nci/bcr/xml/clinical/shared/2.5" />
17	<xs:annotation>	+-
18	<xs:appinfo>
19	<jaxb:globalBindings generateIsSetMethod="true" />
20	<jaxb:schemaBindings>
21	<jaxb:package name="nci.tcga.bcr.xml.jaxb.clinical.gbm" />
22	</jaxb:schemaBindings>
23	</xs:appinfo>
24	</xs:annotation>
26	<xs:annotation>	+-
27	<xs:documentation xml:lang="en">Schema to define the elements of the TCGA Clinical Data Follow-up Form within the GBM study.</xs:documentation>
28	</xs:annotation>
30	<xs:element name="follow_up_v1.0">	+-
31	<xs:complexType>
33	<xs:sequence>	+-
34	<xs:element ref="shared:bcr_patient_barcode" />
35	<xs:element ref="shared:bcr_patient_uuid" />
36	<xs:element ref="shared:vital_status" />
37	<xs:choice>
38	<xs:sequence>
39	<xs:element ref="shared:day_of_last_followup" />
40	<xs:element ref="shared:month_of_last_followup" />
41	<xs:element ref="shared:year_of_last_followup" />
42	</xs:sequence>
43	<xs:element ref="shared:days_to_last_followup" />
44	</xs:choice>
45	<xs:choice>
46	<xs:sequence>
47	<xs:element ref="shared:day_of_death" />
48	<xs:element ref="shared:month_of_death" />
49	<xs:element ref="shared:year_of_death" />
50	</xs:sequence>
51	<xs:element ref="shared:days_to_death" />
52	</xs:choice>
53	<xs:choice>
54	<xs:sequence>
55	<xs:element ref="shared:day_of_new_tumor_event_after_initial_treatment" />
56	<xs:element ref="shared:month_of_new_tumor_event_after_initial_treatment" />
57	<xs:element ref="shared:year_of_new_tumor_event_after_initial_treatment" />
58	</xs:sequence>
59	<xs:element ref="shared:days_to_new_tumor_event_after_initial_treatment" />
60	</xs:choice>
61	<xs:element ref="shared:additional_surgery_locoregional_procedure" />
62	<xs:choice>
63	<xs:sequence>
64	<xs:element ref="shared:day_of_additional_surgery_locoregional_procedure" />
65	<xs:element ref="shared:month_of_additional_surgery_locoregional_procedure" />
66	<xs:element ref="shared:year_of_additional_surgery_locoregional_procedure" />
67	</xs:sequence>
68	<xs:element ref="shared:days_to_additional_surgery_locoregional_procedure" />
69	</xs:choice>
70	<xs:choice>
71	<xs:sequence>
72	<xs:element ref="shared:day_of_tumor_progression" />
73	<xs:element ref="shared:month_of_tumor_progression" />
74	<xs:element ref="shared:year_of_tumor_progression" />
75	</xs:sequence>
76	<xs:element ref="shared:days_to_tumor_progression" />
77	</xs:choice>
78	<xs:choice>
79	<xs:sequence>
80	<xs:element ref="shared:day_of_tumor_recurrence" />
81	<xs:element ref="shared:month_of_tumor_recurrence" />
82	<xs:element ref="shared:year_of_tumor_recurrence" />
83	</xs:sequence>
84	<xs:element ref="shared:days_to_tumor_recurrence" />
85	</xs:choice>
86	<xs:element ref="shared:person_neoplasm_cancer_status" />
87	<xs:element ref="shared:additional_pharmaceutical_therapy" />
88	<xs:element ref="shared:additional_radiation_therapy" />
89	<xs:element ref="shared:targeted_molecular_therapy" />
90	<xs:element ref="shared:radiation_therapy" />
91	<xs:element ref="shared:additional_surgery_metastatic_procedure" />
92	<xs:choice>
93	<xs:sequence>
94	<xs:element ref="shared:day_of_additional_surgery_metastatic_procedure" />
95	<xs:element ref="shared:month_of_additional_surgery_metastatic_procedure" />
96	<xs:element ref="shared:year_of_additional_surgery_metastatic_procedure" />
97	</xs:sequence>
98	<xs:element ref="shared:days_to_additional_surgery_metastatic_procedure" />
99	</xs:choice>
100	<xs:choice>
101	<xs:sequence>
102	<xs:element ref="shared:day_of_form_completion" />
103	<xs:element ref="shared:month_of_form_completion" />
104	<xs:element ref="shared:year_of_form_completion" />
105	</xs:sequence>
106	<xs:element ref="shared:days_to_form_completion" />
107	</xs:choice>
109	<xs:element ref="shared:followup_case_report_form_submission_reason" />	+-
111	<xs:element ref="shared:karnofsky_performance_score" />	+-
112	<xs:element ref="shared:eastern_cancer_oncology_group" />
113	<xs:element ref="shared:performance_status_scale_timing" />
114	</xs:sequence>
115	<xs:attribute name="version" type="xs:string" default="1.0" use="optional"/>
116	</xs:complexType>
117	</xs:element>
118	</xs:schema>

   
File: TCGA_BCR.HNSC_Clinical.xsd  

4	<xs:schema xmlns:xs="http://www.w3.org/2001/XMLSchema" xmlns:utility="http://tcga.nci/bcr/xml/utility/2.5" xmlns:admin="http://tcga.nci/bcr/xml/administration/2.5" xmlns:shared="http://tcga.nci/bcr/xml/clinical/shared/2.5" xmlns:rad="http://tcga.nci/bcr/xml/clinical/radiation/2.5" xmlns:rx="http://tcga.nci/bcr/xml/clinical/pharmaceutical/2.5" xmlns:cqcf="http://tcga.nci/bcr/xml/clinical/cqcf/2.5" xmlns:follow_up_v1.0="http://tcga.nci/bcr/xml/clinical/hnsc/followup/2.5/1.0" xmlns="http://tcga.nci/bcr/xml/clinical/hnsc/2.5" xmlns:jaxb="http://java.sun.com/xml/ns/jaxb" targetNamespace="http://tcga.nci/bcr/xml/clinical/hnsc/2.5" elementFormDefault="qualified" version="2.5.0" jaxb:version="1.0">	<>	3
			4	<xs:schema elementFormDefault="qualified" version="2.4.4"
			5	xmlns:xs="http://www.w3.org/2001/XMLSchema"
			6	xmlns:utility="http://tcga.nci/bcr/xml/utility/2.4"
			7	xmlns:admin="http://tcga.nci/bcr/xml/administration/2.4"
			8	xmlns:shared="http://tcga.nci/bcr/xml/clinical/shared/2.4"
			9	xmlns:rad="http://tcga.nci/bcr/xml/clinical/radiation/2.4"
			10	xmlns:rx="http://tcga.nci/bcr/xml/clinical/pharmaceutical/2.4"
			11	xmlns="http://tcga.nci/bcr/xml/clinical/hnsc/2.4"
			12	targetNamespace="http://tcga.nci/bcr/xml/clinical/hnsc/2.4"
			13	xmlns:jaxb="http://java.sun.com/xml/ns/jaxb" jaxb:version="1.0">
16	<xs:import namespace="http://tcga.nci/bcr/xml/utility/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/utility/2.5/TCGA_BCR.Utility.xsd"/>	<>	28	<xs:import namespace="http://tcga.nci/bcr/xml/utility/2.4" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/utility/2.4/TCGA_BCR.Utility.xsd" />
17	<xs:import namespace="http://tcga.nci/bcr/xml/administration/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/administration/2.5/TCGA_BCR.Administration.xsd"/>		29	<xs:import namespace="http://tcga.nci/bcr/xml/administration/2.4" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/administration/2.4/TCGA_BCR.Administration.xsd" />
18	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/shared/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/shared/2.5/TCGA_BCR.Shared_Clinical_Elements.xsd"/>		30	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/shared/2.4" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/shared/2.4/TCGA_BCR.Shared_Clinical_Elements.xsd" />
19	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/radiation/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/radiation/2.5/TCGA_BCR.Radiation.xsd"/>		31	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/radiation/2.4" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/radiation/2.4/TCGA_BCR.Radiation.xsd" />
20	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/pharmaceutical/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/pharmaceutical/2.5/TCGA_BCR.Pharmaceutical.xsd"/>		32	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/pharmaceutical/2.4" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/pharmaceutical/2.4/TCGA_BCR.Pharmaceutical.xsd" />
21	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/hnsc/followup/2.5/1.0" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/hnsc/followup/2.5/TCGA_BCR.HNSC_Clinical_FollowUp_v1.0.xsd"/>		33
22	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/cqcf/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/cqcf/2.5/TCGA_BCR.CQCF.xsd"/>
29	<xs:attribute name="schemaVersion" type="xs:decimal" use="required" fixed="2.5"/>	<>	41	<xs:attribute name="schemaVersion" type="xs:decimal" use="required" fixed="2.4"/>
105	<xs:element ref="shared:anatomic_organ_subdivision"/>	<>	135	<xs:element ref="anatomic_organ_subdivision" />
107	<xs:element ref="shared:primary_lymph_node_presentation_assessment"/>	<>	137	<xs:element ref="lymphnodes_examined" />
108	<xs:element ref="shared:lymph_node_examined_count"/>		138	<xs:element ref="number_of_lymphnodes_examined" />
109	<xs:element ref="shared:number_of_lymphnodes_positive_by_he"/>		139	<xs:element ref="number_of_lymphnodes_positive_by_he" />
110	<xs:element ref="shared:number_of_lymphnodes_positive_by_ihc"/>		140	<xs:element ref="number_of_lymphnodes_positive_by_ihc" />
117	<xs:element ref="shared:margin_status"/>	<>	147	<xs:element ref="margin_status" />
121	<xs:element ref="shared:lymphovascular_invasion_present"/>	<>	151	<xs:element ref="lymphovascular_invasion_present" />
123	<xs:element ref="shared:neoplasm_histologic_grade"/>	<>	153	<xs:element ref="tumor_grade" />
128	<xs:element ref="shared:stopped_smoking_year"/>	<>	158	<xs:element ref="year_of_tobacco_smoking_cessation" />
129	<xs:element ref="shared:number_pack_years_smoked"/>		159	<xs:element ref="number_pack_years_smoked" />
135	<xs:element ref="clinical_cqcf"/>	+-
136	<xs:element name="follow_ups">
137	<xs:annotation>
138	<xs:documentation>We are using namespaces and version numbers to distinguish one version of followup from another.</xs:documentation>
139	</xs:annotation>
140	<xs:complexType>
141	<xs:sequence>
142	<xs:element ref="follow_up_v1.0:follow_up_v1.0" minOccurs="0" maxOccurs="unbounded"/>
146	</xs:sequence>	<>	168
147	</xs:complexType>
148	</xs:element>
149	<xs:element name="clinical_cqcf">		169	<xs:element name="tumor_grade" nillable="true">
151	<xs:sequence>	<>	171	<xs:simpleContent>
152	<xs:element ref="cqcf:frozen_specimen_anatomic_site"/>
153	<xs:element ref="cqcf:history_of_prior_malignancy"/>
154	<xs:element ref="cqcf:history_of_neoadjuvant_treatment"/>
155	<xs:element ref="cqcf:consent_or_death_status"/>		172	<xs:restriction base="utility:clinical_res_attributes">
156	<xs:choice>
157	<xs:choice>
158	<xs:sequence>
159	<xs:element ref="cqcf:day_of_consent"/>		173	<xs:enumeration value="" />
160	<xs:element ref="cqcf:month_of_consent"/>
161	<xs:element ref="cqcf:year_of_consent"/>		174	<xs:enumeration value="GX" />
162	</xs:sequence>
163	<xs:element ref="cqcf:days_to_consent"/>
164	</xs:choice>
165	<xs:choice>
166	<xs:sequence>
167	<xs:element ref="shared:day_of_death"/>		175	<xs:enumeration value="G1" />
168	<xs:element ref="shared:month_of_death"/>		176	<xs:enumeration value="G2" />
169	<xs:element ref="shared:year_of_death"/>
170	</xs:sequence>
171	<xs:element ref="shared:days_to_death"/>
172	</xs:choice>
173	</xs:choice>
174	<xs:element ref="cqcf:diagnosis_subtype"/>		177	<xs:enumeration value="G3" />
175	<xs:element ref="shared:prior_diagnosis"/>		178	<xs:enumeration value="G4" />
176	<xs:element ref="cqcf:normal_tissue_anatomic_site"/>
177	<xs:element ref="cqcf:normal_tissue_proximity"/>		179	<xs:attribute name="cde" type="xs:string" default="2785839" />
178	<xs:element ref="cqcf:tumor_type"/>
179	<xs:element ref="cqcf:histological_subtype" minOccurs="0"/>		180	<xs:attribute name="xsd_ver" type="xs:string" default="1.11" />
180	<xs:element ref="cqcf:other_anatomic_site" minOccurs="0"/>		181	<xs:attribute name="tier" type="xs:string" default="1" />
181	<xs:element ref="cqcf:country"/>		182	</xs:restriction>
182	</xs:sequence>		183	</xs:simpleContent>
		-+	203	<xs:element name="number_pack_years_smoked" nillable="true">
			204	<xs:complexType mixed="true">
			205	<xs:simpleContent>
			206	<xs:restriction base="utility:clinical_res_attributes">
			207	<xs:attribute name="cde" type="xs:string" default="2955385" />
			208	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
			209	<xs:attribute name="tier" type="xs:string" default="1" />
			210	</xs:restriction>
			211	</xs:simpleContent>
			212	</xs:complexType>
			213	</xs:element>
		-+	264	<xs:element name="margin_status" nillable="true">
			265	<xs:complexType>
			266	<xs:simpleContent>
			267	<xs:restriction base="utility:clinical_res_attributes">
			268	<xs:enumeration value="" />
			269	<xs:enumeration value="Negative" />
			270	<xs:enumeration value="Close" />
			271	<xs:enumeration value="Positive" />
			272	<xs:attribute name="cde" type="xs:string" default="3114007" />
			273	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			274	<xs:attribute name="tier" type="xs:string" default="1" />
			275	</xs:restriction>
			276	</xs:simpleContent>
			277	</xs:complexType>
			278	</xs:element>
		-+	353	<xs:element name="lymphovascular_invasion_present" nillable="true">
			354	<xs:complexType>
			355	<xs:simpleContent>
			356	<xs:extension base="utility:yes_or_no">
			357	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			358	<xs:attribute name="cde" type="xs:string" default="64727" />
			359	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			360	<xs:attribute name="tier" type="xs:string" default="1" />
			361	</xs:extension>
			362	</xs:simpleContent>
			363	</xs:complexType>
			364	</xs:element>
		-+	432	<xs:element name="year_of_tobacco_smoking_cessation" nillable="true">
			433	<xs:complexType mixed="true">
			434	<xs:simpleContent>
			435	<xs:extension base="utility:generic_year">
			436	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			437	<xs:attribute name="cde" type="xs:string" default="2228610" />
			438	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
			439	<xs:attribute name="tier" type="xs:string" default="1" />
			440	</xs:extension>
			441	</xs:simpleContent>
			442	</xs:complexType>
			443	</xs:element>
		-+	445	<xs:element name="lymphnodes_examined" nillable="true">
			446	<xs:complexType>
			447	<xs:simpleContent>
			448	<xs:extension base="utility:yes_or_no">
			449	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			450	<xs:attribute name="cde" type="xs:string" default="2200396" />
			451	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
			452	<xs:attribute name="tier" type="xs:string" default="1" />
			453	</xs:extension>
			454	</xs:simpleContent>
			455	</xs:complexType>
			456	</xs:element>
		-+	458	<xs:element name="number_of_lymphnodes_positive_by_he" nillable="true">
			459	<xs:complexType mixed="true">
			460	<xs:simpleContent>
			461	<xs:restriction base="utility:clinical_res_attributes">
			462	<xs:attribute name="cde" type="xs:string" default="3086388" />
			463	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
			464	<xs:attribute name="tier" type="xs:string" default="1" />
			465	</xs:restriction>
			466	</xs:simpleContent>
			467	</xs:complexType>
			468	</xs:element>
		-+	483	<xs:element name="anatomic_organ_subdivision" nillable="true">
			484	<xs:complexType mixed="true">
			485	<xs:simpleContent>
			486	<xs:restriction base="utility:clinical_res_attributes">
			487	<xs:enumeration value="" />
			488	<xs:enumeration value="Oral Cavity" />
			489	<xs:enumeration value="Lip" />
			490	<xs:enumeration value="Oral Tongue" />
			491	<xs:enumeration value="Alveolar Ridge" />
			492	<xs:enumeration value="Floor of Mouth" />
			493	<xs:enumeration value="Hard Palate" />
			494	<xs:enumeration value="Buccal Mucosa" />
			495	<xs:enumeration value="Oropharynx" />
			496	<xs:enumeration value="Tonsil" />
			497	<xs:enumeration value="Base of Tongue" />
			498	<xs:enumeration value="Hypopharynx" />
			499	<xs:enumeration value="Larynx" />
			500	<xs:enumeration value="Other" />
			501	<xs:attribute name="cde" type="xs:string" default="3108203" />
			502	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
			503	<xs:attribute name="tier" type="xs:string" default="2" />
			504	</xs:restriction>
			505	</xs:simpleContent>
			506	</xs:complexType>
			507	</xs:element>
		-+	599	<xs:element name="number_of_lymphnodes_examined" nillable="true">
			600	<xs:complexType mixed="true">
			601	<xs:simpleContent>
			602	<xs:restriction base="utility:clinical_res_attributes">
			603	<xs:attribute name="cde" type="xs:string" default="3" />
			604	<xs:attribute name="xsd_ver" type="xs:string" default="2.1" />
			605	<xs:attribute name="tier" type="xs:string" default="1" />
			606	</xs:restriction>
			607	</xs:simpleContent>
			608	</xs:complexType>
			609	</xs:element>
		-+	611	<xs:element name="number_of_lymphnodes_positive_by_ihc" nillable="true">
			612	<xs:complexType mixed="true">
			613	<xs:simpleContent>
			614	<xs:restriction base="utility:clinical_res_attributes">
			615	<xs:attribute name="cde" type="xs:string" default="3086383" />
			616	<xs:attribute name="xsd_ver" type="xs:string" default="2.1" />
			617	<xs:attribute name="tier" type="xs:string" default="1" />
			618	</xs:restriction>
			619	</xs:simpleContent>
			620	</xs:complexType>
			621	</xs:element>

   
File: TCGA_BCR.HNSC_Clinical_FollowUp_v1.0.xsd  

1	<?xml version="1.0" encoding="utf-8" ?>	+-
4	<xs:schema elementFormDefault="qualified" version="2.5.0"	+-
5	xmlns:xs="http://www.w3.org/2001/XMLSchema"
6	xmlns:shared="http://tcga.nci/bcr/xml/clinical/shared/2.5"
7	xmlns:utility="http://tcga.nci/bcr/xml/utility/2.5"
8	xmlns:admin="http://tcga.nci/bcr/xml/administration/2.5"
9	xmlns="http://tcga.nci/bcr/xml/clinical/hnsc/followup/2.5/1.0"
10	targetNamespace="http://tcga.nci/bcr/xml/clinical/hnsc/followup/2.5/1.0"
11	xmlns:jaxb="http://java.sun.com/xml/ns/jaxb" jaxb:version="1.0" >
13	<xs:import schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/utility/2.5/TCGA_BCR.Utility.xsd" namespace="http://tcga.nci/bcr/xml/utility/2.5" />	+-
14	<xs:import schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/administration/2.5/TCGA_BCR.Administration.xsd" namespace="http://tcga.nci/bcr/xml/administration/2.5" />
15	<xs:import schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/shared/2.5/TCGA_BCR.Shared_Clinical_Elements.xsd" namespace="http://tcga.nci/bcr/xml/clinical/shared/2.5" />
17	<xs:annotation>	+-
18	<xs:appinfo>
19	<jaxb:globalBindings generateIsSetMethod="true" />
20	<jaxb:schemaBindings>
21	<jaxb:package name="nci.tcga.bcr.xml.jaxb.clinical.hnsc" />
22	</jaxb:schemaBindings>
23	</xs:appinfo>
24	</xs:annotation>
26	<xs:annotation>	+-
27	<xs:documentation xml:lang="en">Schema to define the elements of the TCGA Clinical Data Follow-up Form within the HNSC study.</xs:documentation>
28	</xs:annotation>
30	<xs:element name="follow_up_v1.0">	+-
31	<xs:complexType>
32	<xs:sequence>
33	<xs:element ref="shared:bcr_patient_barcode" />
34	<xs:element ref="shared:bcr_patient_uuid" />
35	<xs:element ref="shared:vital_status" />
36	<xs:choice>
37	<xs:sequence>
38	<xs:element ref="shared:day_of_last_followup" />
39	<xs:element ref="shared:month_of_last_followup" />
40	<xs:element ref="shared:year_of_last_followup" />
41	</xs:sequence>
42	<xs:element ref="shared:days_to_last_followup" />
43	</xs:choice>
44	<xs:choice>
45	<xs:sequence>
46	<xs:element ref="shared:day_of_death" />
47	<xs:element ref="shared:month_of_death" />
48	<xs:element ref="shared:year_of_death" />
49	</xs:sequence>
50	<xs:element ref="shared:days_to_death" />
51	</xs:choice>
52	<xs:element ref="shared:new_tumor_event_after_initial_treatment" />
53	<xs:choice>
54	<xs:sequence>
55	<xs:element ref="shared:day_of_new_tumor_event_after_initial_treatment" />
56	<xs:element ref="shared:month_of_new_tumor_event_after_initial_treatment" />
57	<xs:element ref="shared:year_of_new_tumor_event_after_initial_treatment" />
58	</xs:sequence>
59	<xs:element ref="shared:days_to_new_tumor_event_after_initial_treatment" />
60	</xs:choice>
61	<xs:element ref="shared:additional_surgery_locoregional_procedure" />
62	<xs:choice>
63	<xs:sequence>
64	<xs:element ref="shared:day_of_additional_surgery_locoregional_procedure" />
65	<xs:element ref="shared:month_of_additional_surgery_locoregional_procedure" />
66	<xs:element ref="shared:year_of_additional_surgery_locoregional_procedure" />
67	</xs:sequence>
68	<xs:element ref="shared:days_to_additional_surgery_locoregional_procedure" />
69	</xs:choice>
70	<xs:element ref="shared:person_neoplasm_cancer_status" />
71	<xs:element ref="shared:additional_radiation_therapy" />
72	<xs:element ref="shared:radiation_therapy" />
73	<xs:element ref="shared:targeted_molecular_therapy" />
74	<xs:element ref="shared:additional_pharmaceutical_therapy" />
75	<xs:element ref="shared:additional_surgery_metastatic_procedure" />
76	<xs:choice>
77	<xs:sequence>
78	<xs:element ref="shared:day_of_additional_surgery_metastatic_procedure" />
79	<xs:element ref="shared:month_of_additional_surgery_metastatic_procedure" />
80	<xs:element ref="shared:year_of_additional_surgery_metastatic_procedure" />
81	</xs:sequence>
82	<xs:element ref="shared:days_to_additional_surgery_metastatic_procedure" />
83	</xs:choice>
84	<xs:choice>
85	<xs:sequence>
86	<xs:element ref="shared:day_of_form_completion" />
87	<xs:element ref="shared:month_of_form_completion" />
88	<xs:element ref="shared:year_of_form_completion" />
89	</xs:sequence>
90	<xs:element ref="shared:days_to_form_completion" />
91	</xs:choice>
93	<xs:element ref="shared:followup_case_report_form_submission_reason" />	+-
96	<xs:element ref="new_neoplasm_event_occurrence_anatomic_site" />	+-
97	<xs:element ref="new_neoplasm_occurrence_anatomic_site_text" />
98	<xs:element ref="primary_therapy_outcome_success" />
99	<xs:element ref="shared:followup_treatment_success" />
100	</xs:sequence>
101	<xs:attribute name="version" type="xs:string" default="1.0" use="optional"/>
102	</xs:complexType>
103	</xs:element>
107	<xs:element name="new_neoplasm_event_occurrence_anatomic_site" nillable="true">	+-
108	<xs:complexType mixed="true">
109	<xs:simpleContent>
110	<xs:restriction base="utility:clinical_res_attributes">
111	<xs:enumeration value="" />
112	<xs:enumeration value="Anus" />
113	<xs:enumeration value="Bladder" />
114	<xs:enumeration value="Bone" />
115	<xs:enumeration value="Brain" />
116	<xs:enumeration value="Cervical Lymph Node" />
117	<xs:enumeration value="Cervix" />
118	<xs:enumeration value="Distant Metastasis " />
119	<xs:enumeration value="Head &amp; Neck" />
120	<xs:enumeration value="Hypopharynx" />
121	<xs:enumeration value="Larynx" />
122	<xs:enumeration value="Liver" />
123	<xs:enumeration value="Lung" />
124	<xs:enumeration value="Lymph Node Only" />
125	<xs:enumeration value="Non-regional / Distant Lymph Nodes" />
126	<xs:enumeration value="Not Applicable" />
127	<xs:enumeration value="Oral Cavity" />
128	<xs:enumeration value="Oropharynx" />
129	<xs:enumeration value="Other, specify" />
130	<xs:enumeration value="Peritoneal Surfaces" />
131	<xs:enumeration value="Renal Pelvis" />
132	<xs:enumeration value="Ureter" />
133	<xs:enumeration value="Urethra" />
134	<xs:enumeration value="Vulva" />
135	<xs:attribute name="cde" type="xs:string" default="3108271" />
136	<xs:attribute name="xsd_ver" type="xs:string" default="2.5" />
137	<xs:attribute name="tier" type="xs:string" default="2" />
138	</xs:restriction>
139	</xs:simpleContent>
140	</xs:complexType>
141	</xs:element>
143	<xs:element name="new_neoplasm_occurrence_anatomic_site_text" nillable="true">	+-
144	<xs:complexType>
145	<xs:simpleContent>
146	<xs:extension base="xs:string">
147	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
148	<xs:attribute name="cde" type="xs:string" default="3128033" />
149	<xs:attribute name="xsd_ver" type="xs:string" default="2.5" />
150	<xs:attribute name="tier" type="xs:string" default="2" />
151	</xs:extension>
152	</xs:simpleContent>
153	</xs:complexType>
154	</xs:element>
157	<xs:element name="primary_therapy_outcome_success" nillable="true">	+-
158	<xs:complexType>
159	<xs:simpleContent>
160	<xs:restriction base="utility:clinical_res_attributes">
161	<xs:enumeration value="" />
162	<xs:enumeration value="Progressive Disease" />
163	<xs:enumeration value="Stable Disease" />
164	<xs:enumeration value="Partial Response" />
165	<xs:enumeration value="Complete Response" />
166	<xs:attribute name="cde" type="xs:string" default="2786727" />
167	<xs:attribute name="xsd_ver" type="xs:string" default="1.11" />
168	<xs:attribute name="tier" type="xs:string" default="2" />
169	</xs:restriction>
170	</xs:simpleContent>
171	</xs:complexType>
172	</xs:element>
174	</xs:schema>	+-

   
File: TCGA_BCR.KIRC_Clinical.xsd  

4	<xs:schema xmlns:xs="http://www.w3.org/2001/XMLSchema" xmlns:utility="http://tcga.nci/bcr/xml/utility/2.5" xmlns:admin="http://tcga.nci/bcr/xml/administration/2.5" xmlns:shared="http://tcga.nci/bcr/xml/clinical/shared/2.5" xmlns:kirc_kirp_shared="http://tcga.nci/bcr/xml/clinical/shared/kirc_kirp/2.5" xmlns:rad="http://tcga.nci/bcr/xml/clinical/radiation/2.5" xmlns:rx="http://tcga.nci/bcr/xml/clinical/pharmaceutical/2.5" xmlns:cqcf="http://tcga.nci/bcr/xml/clinical/cqcf/2.5" xmlns:kirc_shared="http://tcga.nci/bcr/xml/clinical/kirc/shared/2.5" xmlns:follow_up_v1.0="http://tcga.nci/bcr/xml/clinical/kirc/followup/2.5/1.0" xmlns="http://tcga.nci/bcr/xml/clinical/kirc/2.5" xmlns:jaxb="http://java.sun.com/xml/ns/jaxb" targetNamespace="http://tcga.nci/bcr/xml/clinical/kirc/2.5" elementFormDefault="qualified" version="2.5.0" jaxb:version="1.0">	<>	3
			4	<xs:schema elementFormDefault="qualified" version="2.4.4"
			5	xmlns:xs="http://www.w3.org/2001/XMLSchema"
			6	xmlns:utility="http://tcga.nci/bcr/xml/utility/2.4"
			7	xmlns:admin="http://tcga.nci/bcr/xml/administration/2.4"
			8	xmlns:shared="http://tcga.nci/bcr/xml/clinical/shared/2.4"
			9	xmlns:rad="http://tcga.nci/bcr/xml/clinical/radiation/2.4"
			10	xmlns:rx="http://tcga.nci/bcr/xml/clinical/pharmaceutical/2.4"
			11	xmlns="http://tcga.nci/bcr/xml/clinical/kirc/2.4"
			12	targetNamespace="http://tcga.nci/bcr/xml/clinical/kirc/2.4"
			13	xmlns:jaxb="http://java.sun.com/xml/ns/jaxb" jaxb:version="1.0">
16	<xs:import namespace="http://tcga.nci/bcr/xml/utility/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/utility/2.5/TCGA_BCR.Utility.xsd"/>	<>	28	<xs:import namespace="http://tcga.nci/bcr/xml/utility/2.4" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/utility/2.4/TCGA_BCR.Utility.xsd" />
17	<xs:import namespace="http://tcga.nci/bcr/xml/administration/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/administration/2.5/TCGA_BCR.Administration.xsd"/>		29	<xs:import namespace="http://tcga.nci/bcr/xml/administration/2.4" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/administration/2.4/TCGA_BCR.Administration.xsd" />
18	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/shared/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/shared/2.5/TCGA_BCR.Shared_Clinical_Elements.xsd"/>		30	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/shared/2.4" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/shared/2.4/TCGA_BCR.Shared_Clinical_Elements.xsd" />
19	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/radiation/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/radiation/2.5/TCGA_BCR.Radiation.xsd"/>		31	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/radiation/2.4" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/radiation/2.4/TCGA_BCR.Radiation.xsd" />
20	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/pharmaceutical/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/pharmaceutical/2.5/TCGA_BCR.Pharmaceutical.xsd"/>		32	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/pharmaceutical/2.4" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/pharmaceutical/2.4/TCGA_BCR.Pharmaceutical.xsd" />
21	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/cqcf/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/cqcf/2.5/TCGA_BCR.CQCF.xsd"/>		33
22	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/kirc/followup/2.5/1.0" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/kirc/followup/2.5/TCGA_BCR.KIRC_Clinical_FollowUp_v1.0.xsd"/>
23	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/shared/kirc_kirp/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/shared/2.5/TCGA_BCR.Shared_Clinical_KIRC_KIRP_Elements.xsd"/>
30	<xs:attribute name="schemaVersion" type="xs:decimal" use="required" fixed="2.5"/>	<>	41	<xs:attribute name="schemaVersion" type="xs:decimal" use="required" fixed="2.4"/>
37	<xs:element ref="kirc_kirp_shared:histological_type"/>	<>	49	<xs:element ref="histological_type" />
106	<xs:element ref="kirc_kirp_shared:tumor_stage"/>	<>	135	<xs:element ref="laterality" />
107	<xs:element ref="kirc_kirp_shared:primary_tumor_pathologic_spread"/>		136	<xs:element ref="lactate_dehydrogenase_result" />
108	<xs:element ref="kirc_kirp_shared:lymphnode_pathologic_spread"/>		137	<xs:element ref="serum_calcium_result" />
109	<xs:element ref="kirc_kirp_shared:distant_metastasis_pathologic_spread"/>
110	<xs:element ref="kirc_kirp_shared:laterality"/>		138	<xs:element ref="hemoglobin_result" />
111	<xs:element ref="shared:lactate_dehydrogenase_result"/>		139	<xs:element ref="platelet_qualitative_result" />
112	<xs:element ref="kirc_kirp_shared:serum_calcium_result"/>		140	<xs:element ref="white_cell_count_result" />
113	<xs:element ref="kirc_kirp_shared:hemoglobin_result"/>		141	<xs:element ref="erythrocyte_sedimentation_rate_result" />
114	<xs:element ref="kirc_kirp_shared:platelet_qualitative_result"/>		142	<xs:element ref="number_of_lymphnodes_examined" />
115	<xs:element ref="kirc_kirp_shared:white_cell_count_result"/>		143	<xs:element ref="number_of_lymphnodes_positive" />
116	<xs:element ref="kirc_kirp_shared:erythrocyte_sedimentation_rate_result"/>		144	<xs:element ref="primary_tumor_pathologic_spread" />
117	<xs:element ref="shared:lymph_node_examined_count"/>		145	<xs:element ref="lymphnode_pathologic_spread" />
118	<xs:element ref="kirc_kirp_shared:number_of_lymphnodes_positive"/>		146	<xs:element ref="distant_metastasis_pathologic_spread" />
119	<xs:element ref="shared:karnofsky_performance_score"/>		147	<xs:element ref="karnofsky_performance_score" />
120	<xs:element ref="shared:eastern_cancer_oncology_group"/>		148	<xs:element ref="eastern_cancer_oncology_group" />
121	<xs:element ref="shared:primary_lymph_node_presentation_assessment"/>		149	<xs:element ref="lymphnodes_examined_prior_presentation" />
122	<xs:element ref="shared:neoplasm_histologic_grade"/>		150	<xs:element ref="tumor_grade" />
			151	<xs:element ref="tumor_stage" />
		<>	154	</xs:sequence>
			155	</xs:complexType>
125	<xs:element ref="clinical_cqcf"/>		156	</xs:element>
126	<xs:element name="follow_ups">	<>	158	<xs:element name="histological_type" nillable="true">
			159	<xs:complexType mixed="true">
127	<xs:annotation>		160	<xs:simpleContent>
128	<xs:documentation>We are using namespaces and version numbers to distinguish one version of followup from another.</xs:documentation>		161	<xs:restriction base="utility:clinical_res_attributes">
			162	<xs:attribute name="cde" type="xs:string" default="3081934" />
			163	<xs:attribute name="xsd_ver" type="xs:string" default="1.9" />
			164	<xs:attribute name="tier" type="xs:string" default="1" />
			165	</xs:restriction>
129	</xs:annotation>		166	</xs:simpleContent>
			167	</xs:complexType>
			168	</xs:element>
		-+	170	<xs:element name="primary_therapy_outcome_success" nillable="true">
		<>	172	<xs:simpleContent>
			173	<xs:restriction base="utility:clinical_res_attributes">
			174	<xs:enumeration value="" />
			175	<xs:enumeration value="PROGRESSIVE DISEASE" />
			176	<xs:enumeration value="STABLE DISEASE" />
			177	<xs:enumeration value="PARTIAL RESPONSE" />
			178	<xs:enumeration value="COMPLETE RESPONSE" />
			179	<xs:attribute name="cde" type="xs:string" default="2786727" />
			180	<xs:attribute name="xsd_ver" type="xs:string" default="1.11" />
			181	<xs:attribute name="tier" type="xs:string" default="2" />
			182	</xs:restriction>
			183	</xs:simpleContent>
			184	</xs:complexType>
131	<xs:sequence>		185	</xs:element>
132	<xs:element ref="follow_up_v1.0:follow_up_v1.0" minOccurs="0" maxOccurs="unbounded"/>	<>	187	<xs:element name="karnofsky_performance_score" nillable="true">
			188	<xs:complexType>
			189	<xs:simpleContent>
			190	<xs:restriction base="utility:clinical_res_attributes">
			191	<xs:enumeration value="" />
			192	<xs:enumeration value="0" />
			193	<xs:enumeration value="10" />
			194	<xs:enumeration value="20" />
			195	<xs:enumeration value="30" />
			196	<xs:enumeration value="40" />
			197	<xs:enumeration value="50" />
			198	<xs:enumeration value="60" />
			199	<xs:enumeration value="70" />
			200	<xs:enumeration value="80" />
			201	<xs:enumeration value="90" />
			202	<xs:enumeration value="100" />
			203	<xs:attribute name="cde" type="xs:string" default="2003853" />
			204	<xs:attribute name="xsd_ver" type="xs:string" default="1.8" />
			205	<xs:attribute name="tier" type="xs:string" default="2" />
133	</xs:sequence>		206	</xs:restriction>
			207	</xs:simpleContent>
		<>	211	<xs:element name="eastern_cancer_oncology_group">
			212	<xs:complexType>
			213	<xs:simpleContent>
			214	<xs:restriction base="utility:clinical_res_attributes">
			215	<xs:enumeration value="" />
			216	<xs:enumeration value="0" />
			217	<xs:enumeration value="1" />
			218	<xs:enumeration value="2" />
			219	<xs:enumeration value="3" />
			220	<xs:enumeration value="4" />
			221	<xs:attribute name="cde" type="xs:string" default="88" />
			222	<xs:attribute name="xsd_ver" type="xs:string" default="1.9" />
			223	<xs:attribute name="tier" type="xs:string" default="2" />
			224	</xs:restriction>
			225	</xs:simpleContent>
			226	</xs:complexType>
136	</xs:sequence>		227	</xs:element>
		-+	229	<xs:element name="primary_tumor_pathologic_spread" nillable="true">
			230	<xs:complexType>
			231	<xs:simpleContent>
			232	<xs:restriction base="utility:clinical_res_attributes">
			233	<xs:enumeration value="" />
			234	<xs:enumeration value="TX" />
			235	<xs:enumeration value="T0" />
			236	<xs:enumeration value="T1" />
			237	<xs:enumeration value="T1a" />
			238	<xs:enumeration value="T1b" />
			239	<xs:enumeration value="T2" />
			240	<xs:enumeration value="T2a" />
			241	<xs:enumeration value="T2b" />
			242	<xs:enumeration value="T3" />
			243	<xs:enumeration value="T3a" />
			244	<xs:enumeration value="T3b" />
			245	<xs:enumeration value="T3c" />
			246	<xs:enumeration value="T4" />
			247	<xs:enumeration value="T4a" />
			248	<xs:enumeration value="T4b" />
			249	<xs:attribute name="cde" type="xs:string" default="3045435" />
			250	<xs:attribute name="xsd_ver" type="xs:string" default="2.1" />
			251	<xs:attribute name="tier" type="xs:string" default="1" />
			252	</xs:restriction>
			253	</xs:simpleContent>
		<>	257	<xs:element name="lymphnode_pathologic_spread" nillable="true">
			258	<xs:complexType>
			259	<xs:simpleContent>
			260	<xs:restriction base="utility:clinical_res_attributes">
139	<xs:element name="clinical_cqcf">		261	<xs:enumeration value="" />
			262	<xs:enumeration value="NX" />
			263	<xs:enumeration value="N0" />
			264	<xs:enumeration value="N1" />
			265	<xs:attribute name="cde" type="xs:string" default="3065858" />
			266	<xs:attribute name="xsd_ver" type="xs:string" default="2.1" />
			267	<xs:attribute name="tier" type="xs:string" default="1" />
			268	</xs:restriction>
			269	</xs:simpleContent>
			270	</xs:complexType>
			271	</xs:element>
		-+	273	<xs:element name="distant_metastasis_pathologic_spread" nillable="true">
		<>	275	<xs:simpleContent>
			276	<xs:restriction base="utility:clinical_res_attributes">
			277	<xs:enumeration value="" />
			278	<xs:enumeration value="M0" />
			279	<xs:enumeration value="M1" />
			280	<xs:enumeration value="MX" />
			281	<xs:attribute name="cde" type="xs:string" default="3045439" />
			282	<xs:attribute name="xsd_ver" type="xs:string" default="2.1" />
			283	<xs:attribute name="tier" type="xs:string" default="1" />
			284	</xs:restriction>
			285	</xs:simpleContent>
			286	</xs:complexType>
141	<xs:sequence>		287	</xs:element>
		<>	289	<xs:element name="lymphnodes_examined_prior_presentation">
			290	<xs:complexType mixed="true">
			291	<xs:simpleContent>
142	<xs:element ref="shared:anatomic_organ_subdivision"/>		292	<xs:extension base="utility:yes_or_no">
143	<xs:element ref="cqcf:history_of_prior_malignancy"/>		293	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			294	<xs:attribute name="cde" type="xs:string" default="2200396" />
144	<xs:element ref="cqcf:history_of_neoadjuvant_treatment"/>		295	<xs:attribute name="xsd_ver" type="xs:string" default="2.1" />
			296	<xs:attribute name="tier" type="xs:string" default="1" />
			297	</xs:extension>
			298	</xs:simpleContent>
			299	</xs:complexType>
			300	</xs:element>
		<>	302	<xs:element name="number_of_lymphnodes_examined" nillable="true">
			303	<xs:complexType mixed="true">
			304	<xs:simpleContent>
145	<xs:element ref="cqcf:consent_or_death_status"/>		305	<xs:restriction base="utility:clinical_res_attributes">
			306	<xs:attribute name="cde" type="xs:string" default="3" />
			307	<xs:attribute name="xsd_ver" type="xs:string" default="2.1" />
			308	<xs:attribute name="tier" type="xs:string" default="1" />
146	<xs:choice>		309	</xs:restriction>
			310	</xs:simpleContent>
			311	</xs:complexType>
			312	</xs:element>
		<>	314	<xs:element name="number_of_lymphnodes_positive" nillable="true">
			315	<xs:complexType mixed="true">
			316	<xs:simpleContent>
			317	<xs:restriction base="utility:clinical_res_attributes">
			318	<xs:attribute name="cde" type="xs:string" default="89" />
			319	<xs:attribute name="xsd_ver" type="xs:string" default="2.1" />
			320	<xs:attribute name="tier" type="xs:string" default="1" />
147	<xs:choice>		321	</xs:restriction>
			322	</xs:simpleContent>
			323	</xs:complexType>
148	<xs:sequence>		324	</xs:element>
		<>	326	<xs:element name="erythrocyte_sedimentation_rate_result" nillable="true">
			327	<xs:complexType>
			328	<xs:simpleContent>
			329	<xs:restriction base="utility:clinical_res_attributes">
			330	<xs:enumeration value="" />
149	<xs:element ref="cqcf:day_of_consent"/>		331	<xs:enumeration value="Elevated" />
			332	<xs:enumeration value="Normal" />
			333	<xs:attribute name="cde" type="xs:string" default="3104952" />
			334	<xs:attribute name="xsd_ver" type="xs:string" default="2.1" />
			335	<xs:attribute name="tier" type="xs:string" default="1" />
			336	</xs:restriction>
			337	</xs:simpleContent>
			338	</xs:complexType>
			339	</xs:element>
150	<xs:element ref="cqcf:month_of_consent"/>	<>	341	<xs:element name="white_cell_count_result" nillable="true">
			342	<xs:complexType>
			343	<xs:simpleContent>
			344	<xs:restriction base="utility:clinical_res_attributes">
			345	<xs:enumeration value="" />
151	<xs:element ref="cqcf:year_of_consent"/>		346	<xs:enumeration value="Elevated" />
			347	<xs:enumeration value="Normal" />
			348	<xs:enumeration value="Low" />
			349	<xs:attribute name="cde" type="xs:string" default="3104948" />
			350	<xs:attribute name="xsd_ver" type="xs:string" default="2.1" />
			351	<xs:attribute name="tier" type="xs:string" default="1" />
			352	</xs:restriction>
			353	</xs:simpleContent>
			354	</xs:complexType>
152	</xs:sequence>		355	</xs:element>
		<>	357	<xs:element name="platelet_qualitative_result" nillable="true">
			358	<xs:complexType>
			359	<xs:simpleContent>
			360	<xs:restriction base="utility:clinical_res_attributes">
			361	<xs:enumeration value="" />
153	<xs:element ref="cqcf:days_to_consent"/>		362	<xs:enumeration value="Elevated" />
			363	<xs:enumeration value="Normal" />
			364	<xs:enumeration value="Low" />
			365	<xs:attribute name="cde" type="xs:string" default="3104944" />
			366	<xs:attribute name="xsd_ver" type="xs:string" default="2.1" />
			367	<xs:attribute name="tier" type="xs:string" default="1" />
154	</xs:choice>		368	</xs:restriction>
			369	</xs:simpleContent>
155	<xs:choice>		370	</xs:complexType>
156	<xs:sequence>		371	</xs:element>
		<>	373	<xs:element name="hemoglobin_result" nillable="true">
			374	<xs:complexType>
			375	<xs:simpleContent>
			376	<xs:restriction base="utility:clinical_res_attributes">
			377	<xs:enumeration value="" />
157	<xs:element ref="shared:day_of_death"/>		378	<xs:enumeration value="Elevated" />
158	<xs:element ref="shared:month_of_death"/>		379	<xs:enumeration value="Normal" />
			380	<xs:enumeration value="Low" />
			381	<xs:attribute name="cde" type="xs:string" default="3113466" />
159	<xs:element ref="shared:year_of_death"/>		382	<xs:attribute name="xsd_ver" type="xs:string" default="2.1" />
			383	<xs:attribute name="tier" type="xs:string" default="1" />
			384	</xs:restriction>
			385	</xs:simpleContent>
			386	</xs:complexType>
160	</xs:sequence>		387	</xs:element>
		<>	389	<xs:element name="serum_calcium_result" nillable="true">
			390	<xs:complexType>
			391	<xs:simpleContent>
			392	<xs:restriction base="utility:clinical_res_attributes">
			393	<xs:enumeration value="" />
161	<xs:element ref="shared:days_to_death"/>		394	<xs:enumeration value="Elevated" />
			395	<xs:enumeration value="Normal" />
			396	<xs:enumeration value="Low" />
			397	<xs:attribute name="cde" type="xs:string" default="3113470" />
			398	<xs:attribute name="xsd_ver" type="xs:string" default="2.1" />
			399	<xs:attribute name="tier" type="xs:string" default="1" />
162	</xs:choice>		400	</xs:restriction>
			401	</xs:simpleContent>
163	</xs:choice>		402	</xs:complexType>
			403	</xs:element>
		<>	405	<xs:element name="lactate_dehydrogenase_result" nillable="true">
			406	<xs:complexType>
			407	<xs:simpleContent>
			408	<xs:restriction base="utility:clinical_res_attributes">
			409	<xs:enumeration value="" />
			410	<xs:enumeration value="Elevated" />
			411	<xs:enumeration value="Normal" />
			412	<xs:attribute name="cde" type="xs:string" default="3113468" />
164	<xs:element ref="cqcf:diagnosis_subtype"/>		413	<xs:attribute name="xsd_ver" type="xs:string" default="2.1" />
165	<xs:element ref="shared:prior_diagnosis"/>		414	<xs:attribute name="tier" type="xs:string" default="1" />
			415	</xs:restriction>
			416	</xs:simpleContent>
			417	</xs:complexType>
			418	</xs:element>
166	<xs:element ref="cqcf:normal_tissue_anatomic_site"/>	<>	420	<xs:element name="laterality" nillable="true">
			421	<xs:complexType>
			422	<xs:simpleContent>
167	<xs:element ref="cqcf:normal_tissue_proximity"/>		423	<xs:restriction base="utility:clinical_res_attributes">
			424	<xs:enumeration value="" />
			425	<xs:enumeration value="Right" />
168	<xs:element ref="cqcf:tumor_type"/>		426	<xs:enumeration value="Left" />
			427	<xs:enumeration value="Bilateral" />
169	<xs:element ref="cqcf:histological_subtype" minOccurs="0"/>		428	<xs:attribute name="cde" type="xs:string" default="827" />
			429	<xs:attribute name="xsd_ver" type="xs:string" default="2.1" />
			430	<xs:attribute name="tier" type="xs:string" default="1" />
			431	</xs:restriction>
			432	</xs:simpleContent>
			433	</xs:complexType>
			434	</xs:element>
170	<xs:element ref="cqcf:other_anatomic_site" minOccurs="0"/>	<>	436	<xs:element name="tumor_grade" nillable="true">
			437	<xs:complexType>
			438	<xs:simpleContent>
			439	<xs:restriction base="utility:clinical_res_attributes">
171	<xs:element ref="cqcf:country"/>		440	<xs:enumeration value="" />
			441	<xs:enumeration value="GX" />
			442	<xs:enumeration value="G1" />
			443	<xs:enumeration value="G2" />
			444	<xs:enumeration value="G3" />
			445	<xs:enumeration value="G4" />
			446	<xs:attribute name="cde" type="xs:string" default="2785839" />
			447	<xs:attribute name="xsd_ver" type="xs:string" default="1.11" />
			448	<xs:attribute name="tier" type="xs:string" default="1" />
			449	</xs:restriction>
			450	</xs:simpleContent>
			451	</xs:complexType>
172	</xs:sequence>		452	</xs:element>
		-+	454	<xs:element name="tumor_stage" nillable="true">
			455	<xs:complexType>
			456	<xs:simpleContent>
			457	<xs:restriction base="utility:clinical_res_attributes">
			458	<xs:enumeration value="" />
			459	<xs:enumeration value="Stage I" />
			460	<xs:enumeration value="Stage II" />
			461	<xs:enumeration value="Stage III" />
			462	<xs:enumeration value="Stage IV" />
			463	<xs:attribute name="cde" type="xs:string" default="3065862" />
			464	<xs:attribute name="xsd_ver" type="xs:string" default="1.11" />
			465	<xs:attribute name="tier" type="xs:string" default="1" />
			466	</xs:restriction>
			467	</xs:simpleContent>

   
File: TCGA_BCR.KIRC_Clinical_FollowUp_v1.0.xsd  

1	<?xml version="1.0" encoding="utf-8" ?>	+-
3	<xs:schema elementFormDefault="qualified" version="2.5.0"	+-
4	xmlns:xs="http://www.w3.org/2001/XMLSchema"
5	xmlns:shared="http://tcga.nci/bcr/xml/clinical/shared/2.5"
6	xmlns:utility="http://tcga.nci/bcr/xml/utility/2.5"
7	xmlns:admin="http://tcga.nci/bcr/xml/administration/2.5"
8	xmlns:kirc_shared="http://tcga.nci/bcr/xml/clinical/kirc/shared/2.5"
9	xmlns="http://tcga.nci/bcr/xml/clinical/kirc/followup/2.5/1.0"
10	targetNamespace="http://tcga.nci/bcr/xml/clinical/kirc/followup/2.5/1.0"
11	xmlns:jaxb="http://java.sun.com/xml/ns/jaxb" jaxb:version="1.0" >
13	<xs:import schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/utility/2.5/TCGA_BCR.Utility.xsd" namespace="http://tcga.nci/bcr/xml/utility/2.5" />	+-
14	<xs:import schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/administration/2.5/TCGA_BCR.Administration.xsd" namespace="http://tcga.nci/bcr/xml/administration/2.5" />
15	<xs:import schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/shared/2.5/TCGA_BCR.Shared_Clinical_Elements.xsd" namespace="http://tcga.nci/bcr/xml/clinical/shared/2.5" />
17	<xs:annotation>	+-
18	<xs:appinfo>
19	<jaxb:globalBindings generateIsSetMethod="true" />
20	<jaxb:schemaBindings>
21	<jaxb:package name="nci.tcga.bcr.xml.jaxb.clinical.kirc" />
22	</jaxb:schemaBindings>
23	</xs:appinfo>
24	</xs:annotation>
26	<xs:annotation>	+-
27	<xs:documentation xml:lang="en">Schema to define the elements of the TCGA Clinical Data Follow-up Form within the KIRC study.</xs:documentation>
28	</xs:annotation>
30	<xs:element name="follow_up_v1.0">	+-
31	<xs:complexType>
32	<xs:sequence>
33	<xs:element ref="shared:bcr_patient_barcode" />
34	<xs:element ref="shared:bcr_patient_uuid" />
35	<xs:element ref="shared:vital_status" />
36	<xs:choice>
37	<xs:sequence>
38	<xs:element ref="shared:day_of_last_followup" />
39	<xs:element ref="shared:month_of_last_followup" />
40	<xs:element ref="shared:year_of_last_followup" />
41	</xs:sequence>
42	<xs:element ref="shared:days_to_last_followup" />
43	</xs:choice>
44	<xs:choice>
45	<xs:sequence>
46	<xs:element ref="shared:day_of_death" />
47	<xs:element ref="shared:month_of_death" />
48	<xs:element ref="shared:year_of_death" />
49	</xs:sequence>
50	<xs:element ref="shared:days_to_death" />
51	</xs:choice>
52	<xs:choice>
53	<xs:sequence>
54	<xs:element ref="shared:day_of_new_tumor_event_after_initial_treatment" />
55	<xs:element ref="shared:month_of_new_tumor_event_after_initial_treatment" />
56	<xs:element ref="shared:year_of_new_tumor_event_after_initial_treatment" />
57	</xs:sequence>
58	<xs:element ref="shared:days_to_new_tumor_event_after_initial_treatment" />
59	</xs:choice>
60	<xs:element ref="shared:additional_surgery_locoregional_procedure" />
61	<xs:choice>
62	<xs:sequence>
63	<xs:element ref="shared:day_of_additional_surgery_locoregional_procedure" />
64	<xs:element ref="shared:month_of_additional_surgery_locoregional_procedure" />
65	<xs:element ref="shared:year_of_additional_surgery_locoregional_procedure" />
66	</xs:sequence>
67	<xs:element ref="shared:days_to_additional_surgery_locoregional_procedure" />
68	</xs:choice>
69	<xs:element ref="shared:person_neoplasm_cancer_status" />
70	<xs:element ref="shared:additional_radiation_therapy" />
71	<xs:element ref="shared:targeted_molecular_therapy" />
72	<xs:element ref="shared:additional_pharmaceutical_therapy" />
73	<xs:element ref="shared:additional_surgery_metastatic_procedure" />
74	<xs:choice>
75	<xs:sequence>
76	<xs:element ref="shared:day_of_additional_surgery_metastatic_procedure" />
77	<xs:element ref="shared:month_of_additional_surgery_metastatic_procedure" />
78	<xs:element ref="shared:year_of_additional_surgery_metastatic_procedure" />
79	</xs:sequence>
80	<xs:element ref="shared:days_to_additional_surgery_metastatic_procedure" />
81	</xs:choice>
82	<xs:choice>
83	<xs:sequence>
84	<xs:element ref="shared:day_of_form_completion" />
85	<xs:element ref="shared:month_of_form_completion" />
86	<xs:element ref="shared:year_of_form_completion" />
87	</xs:sequence>
88	<xs:element ref="shared:days_to_form_completion" />
89	</xs:choice>
91	<xs:element ref="shared:followup_case_report_form_submission_reason" />	+-
94	<xs:element ref="shared:karnofsky_performance_score" />	+-
95	<xs:element ref="shared:eastern_cancer_oncology_group" />
96	<xs:element ref="shared:performance_status_scale_timing" />
97	</xs:sequence>
98	<xs:attribute name="version" type="xs:string" default="1.0" use="optional"/>
99	</xs:complexType>
100	</xs:element>
101	</xs:schema>

   
File: TCGA_BCR.KIRP_Clinical.xsd  

4	<xs:schema xmlns:xs="http://www.w3.org/2001/XMLSchema" xmlns:utility="http://tcga.nci/bcr/xml/utility/2.5" xmlns:admin="http://tcga.nci/bcr/xml/administration/2.5" xmlns:shared="http://tcga.nci/bcr/xml/clinical/shared/2.5" xmlns:kirc_kirp_shared="http://tcga.nci/bcr/xml/clinical/shared/kirc_kirp/2.5" xmlns:rad="http://tcga.nci/bcr/xml/clinical/radiation/2.5" xmlns:rx="http://tcga.nci/bcr/xml/clinical/pharmaceutical/2.5" xmlns:follow_up_v1.0="http://tcga.nci/bcr/xml/clinical/kirp/followup/2.5/1.0" xmlns:cqcf="http://tcga.nci/bcr/xml/clinical/cqcf/2.5" xmlns="http://tcga.nci/bcr/xml/clinical/kirp/2.5" xmlns:jaxb="http://java.sun.com/xml/ns/jaxb" targetNamespace="http://tcga.nci/bcr/xml/clinical/kirp/2.5" elementFormDefault="qualified" version="2.5.2" jaxb:version="1.0">	<>	3
			4	<xs:schema elementFormDefault="qualified" version="2.4.4"
			5	xmlns:xs="http://www.w3.org/2001/XMLSchema"
			6	xmlns:utility="http://tcga.nci/bcr/xml/utility/2.4"
			7	xmlns:admin="http://tcga.nci/bcr/xml/administration/2.4"
			8	xmlns:shared="http://tcga.nci/bcr/xml/clinical/shared/2.4"
			9	xmlns:rad="http://tcga.nci/bcr/xml/clinical/radiation/2.4"
			10	xmlns:rx="http://tcga.nci/bcr/xml/clinical/pharmaceutical/2.4"
			11	xmlns="http://tcga.nci/bcr/xml/clinical/kirp/2.4"
			12	targetNamespace="http://tcga.nci/bcr/xml/clinical/kirp/2.4"
			13	xmlns:jaxb="http://java.sun.com/xml/ns/jaxb" jaxb:version="1.0">
16	<xs:import namespace="http://tcga.nci/bcr/xml/utility/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/utility/2.5/TCGA_BCR.Utility.xsd"/>	<>	28	<xs:import namespace="http://tcga.nci/bcr/xml/utility/2.4" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/utility/2.4/TCGA_BCR.Utility.xsd" />
17	<xs:import namespace="http://tcga.nci/bcr/xml/administration/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/administration/2.5/TCGA_BCR.Administration.xsd"/>		29	<xs:import namespace="http://tcga.nci/bcr/xml/administration/2.4" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/administration/2.4/TCGA_BCR.Administration.xsd" />
18	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/shared/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/shared/2.5/TCGA_BCR.Shared_Clinical_Elements.xsd"/>		30	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/shared/2.4" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/shared/2.4/TCGA_BCR.Shared_Clinical_Elements.xsd" />
19	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/radiation/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/radiation/2.5/TCGA_BCR.Radiation.xsd"/>		31	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/radiation/2.4" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/radiation/2.4/TCGA_BCR.Radiation.xsd" />
20	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/pharmaceutical/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/pharmaceutical/2.5/TCGA_BCR.Pharmaceutical.xsd"/>		32	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/pharmaceutical/2.4" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/pharmaceutical/2.4/TCGA_BCR.Pharmaceutical.xsd" />
21	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/cqcf/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/cqcf/2.5/TCGA_BCR.CQCF.xsd"/>		33
22	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/kirp/followup/2.5/1.0" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/kirp/followup/2.5/TCGA_BCR.KIRP_Clinical_FollowUp_v1.0.xsd"/>
23	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/shared/kirc_kirp/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/shared/2.5/TCGA_BCR.Shared_Clinical_KIRC_KIRP_Elements.xsd"/>
30	<xs:attribute name="schemaVersion" type="xs:decimal" use="required" fixed="2.5"/>	<>	41	<xs:attribute name="schemaVersion" type="xs:decimal" use="required" fixed="2.4"/>
37	<xs:element ref="kirc_kirp_shared:histological_type"/>	<>	49	<xs:element ref="histological_type" />
106	<xs:element ref="kirc_kirp_shared:laterality"/>	<>	135	<xs:element ref="laterality" />
107	<xs:element ref="shared:lactate_dehydrogenase_result"/>		136	<xs:element ref="lactate_dehydrogenase_result" />
108	<xs:element ref="kirc_kirp_shared:serum_calcium_result"/>		137	<xs:element ref="serum_calcium_result" />
109	<xs:element ref="kirc_kirp_shared:hemoglobin_result"/>		138	<xs:element ref="hemoglobin_result" />
110	<xs:element ref="kirc_kirp_shared:platelet_qualitative_result"/>		139	<xs:element ref="platelet_qualitative_result" />
111	<xs:element ref="kirc_kirp_shared:white_cell_count_result"/>		140	<xs:element ref="white_cell_count_result" />
112	<xs:element ref="kirc_kirp_shared:erythrocyte_sedimentation_rate_result"/>		141	<xs:element ref="erythrocyte_sedimentation_rate_result" />
113	<xs:element ref="shared:lymph_node_examined_count"/>		142	<xs:element ref="number_of_lymphnodes_examined" />
114	<xs:element ref="kirc_kirp_shared:number_of_lymphnodes_positive"/>		143	<xs:element ref="number_of_lymphnodes_positive" />
115	<xs:element ref="kirc_kirp_shared:primary_tumor_pathologic_spread"/>		144	<xs:element ref="primary_tumor_pathologic_spread" />
116	<xs:element ref="kirc_kirp_shared:lymphnode_pathologic_spread"/>		145	<xs:element ref="lymphnode_pathologic_spread" />
117	<xs:element ref="kirc_kirp_shared:distant_metastasis_pathologic_spread"/>		146	<xs:element ref="distant_metastasis_pathologic_spread" />
118	<xs:element ref="shared:karnofsky_performance_score"/>		147	<xs:element ref="karnofsky_performance_score" />
119	<xs:element ref="shared:eastern_cancer_oncology_group"/>		148	<xs:element ref="eastern_cancer_oncology_group" />
120	<xs:element ref="shared:primary_lymph_node_presentation_assessment"/>		149	<xs:element ref="lymphnodes_examined_prior_presentation" />
122	<xs:element ref="kirc_kirp_shared:tumor_stage"/>	<>	151	<xs:element ref="tumor_stage" />
		<>	154	</xs:sequence>
			155	</xs:complexType>
125	<xs:element ref="clinical_cqcf"/>		156	</xs:element>
126	<xs:element name="follow_ups">	<>	158	<xs:element name="histological_type" nillable="true">
			159	<xs:complexType mixed="true">
127	<xs:annotation>		160	<xs:simpleContent>
128	<xs:documentation>We are using namespaces and version numbers to distinguish one version of followup from another.</xs:documentation>		161	<xs:restriction base="utility:clinical_res_attributes">
			162	<xs:attribute name="cde" type="xs:string" default="3081934" />
			163	<xs:attribute name="xsd_ver" type="xs:string" default="1.9" />
			164	<xs:attribute name="tier" type="xs:string" default="1" />
			165	</xs:restriction>
129	</xs:annotation>		166	</xs:simpleContent>
			167	</xs:complexType>
			168	</xs:element>
		-+	170	<xs:element name="primary_therapy_outcome_success" nillable="true">
131	<xs:sequence>	<>	172	<xs:simpleContent>
			173	<xs:restriction base="utility:clinical_res_attributes">
			174	<xs:enumeration value="" />
			175	<xs:enumeration value="PROGRESSIVE DISEASE" />
			176	<xs:enumeration value="STABLE DISEASE" />
			177	<xs:enumeration value="PARTIAL RESPONSE" />
			178	<xs:enumeration value="COMPLETE RESPONSE" />
			179	<xs:attribute name="cde" type="xs:string" default="2786727" />
132	<xs:element ref="follow_up_v1.0:follow_up_v1.0" minOccurs="0" maxOccurs="unbounded"/>		180	<xs:attribute name="xsd_ver" type="xs:string" default="1.11" />
			181	<xs:attribute name="tier" type="xs:string" default="2" />
133	</xs:sequence>		182	</xs:restriction>
			183	</xs:simpleContent>
		<>	187	<xs:element name="karnofsky_performance_score" nillable="true">
			188	<xs:complexType>
			189	<xs:simpleContent>
			190	<xs:restriction base="utility:clinical_res_attributes">
			191	<xs:enumeration value="" />
			192	<xs:enumeration value="0" />
			193	<xs:enumeration value="10" />
			194	<xs:enumeration value="20" />
			195	<xs:enumeration value="30" />
			196	<xs:enumeration value="40" />
			197	<xs:enumeration value="50" />
			198	<xs:enumeration value="60" />
			199	<xs:enumeration value="70" />
			200	<xs:enumeration value="80" />
			201	<xs:enumeration value="90" />
			202	<xs:enumeration value="100" />
			203	<xs:attribute name="cde" type="xs:string" default="2003853" />
			204	<xs:attribute name="xsd_ver" type="xs:string" default="1.8" />
			205	<xs:attribute name="tier" type="xs:string" default="2" />
136	</xs:sequence>		206	</xs:restriction>
			207	</xs:simpleContent>
139	<xs:element name="clinical_cqcf">	<>	211	<xs:element name="eastern_cancer_oncology_group">
		<>	213	<xs:simpleContent>
			214	<xs:restriction base="utility:clinical_res_attributes">
			215	<xs:enumeration value="" />
			216	<xs:enumeration value="0" />
			217	<xs:enumeration value="1" />
			218	<xs:enumeration value="2" />
			219	<xs:enumeration value="3" />
			220	<xs:enumeration value="4" />
			221	<xs:attribute name="cde" type="xs:string" default="88" />
			222	<xs:attribute name="xsd_ver" type="xs:string" default="1.9" />
			223	<xs:attribute name="tier" type="xs:string" default="2" />
			224	</xs:restriction>
			225	</xs:simpleContent>
			226	</xs:complexType>
141	<xs:sequence>		227	</xs:element>
142	<xs:element ref="shared:anatomic_organ_subdivision"/>	<>	229	<xs:element name="primary_tumor_pathologic_spread" nillable="true">
			230	<xs:complexType>
			231	<xs:simpleContent>
143	<xs:element ref="cqcf:history_of_prior_malignancy"/>		232	<xs:restriction base="utility:clinical_res_attributes">
			233	<xs:enumeration value="" />
			234	<xs:enumeration value="TX" />
			235	<xs:enumeration value="T0" />
			236	<xs:enumeration value="T1" />
			237	<xs:enumeration value="T1a" />
			238	<xs:enumeration value="T1b" />
			239	<xs:enumeration value="T2" />
			240	<xs:enumeration value="T2a" />
			241	<xs:enumeration value="T2b" />
			242	<xs:enumeration value="T3" />
			243	<xs:enumeration value="T3a" />
			244	<xs:enumeration value="T3b" />
			245	<xs:enumeration value="T3c" />
			246	<xs:enumeration value="T4" />
			247	<xs:enumeration value="T4a" />
			248	<xs:enumeration value="T4b" />
			249	<xs:attribute name="cde" type="xs:string" default="3045435" />
144	<xs:element ref="cqcf:history_of_neoadjuvant_treatment"/>		250	<xs:attribute name="xsd_ver" type="xs:string" default="2.1" />
145	<xs:element ref="cqcf:consent_or_death_status"/>		251	<xs:attribute name="tier" type="xs:string" default="1" />
146	<xs:choice>		252	</xs:restriction>
			253	</xs:simpleContent>
			254	</xs:complexType>
			255	</xs:element>
		<>	257	<xs:element name="lymphnode_pathologic_spread" nillable="true">
			258	<xs:complexType>
			259	<xs:simpleContent>
			260	<xs:restriction base="utility:clinical_res_attributes">
			261	<xs:enumeration value="" />
			262	<xs:enumeration value="NX" />
			263	<xs:enumeration value="N0" />
			264	<xs:enumeration value="N1" />
			265	<xs:attribute name="cde" type="xs:string" default="3065858" />
			266	<xs:attribute name="xsd_ver" type="xs:string" default="2.1" />
			267	<xs:attribute name="tier" type="xs:string" default="1" />
147	<xs:choice>		268	</xs:restriction>
			269	</xs:simpleContent>
			270	</xs:complexType>
148	<xs:sequence>		271	</xs:element>
		<>	273	<xs:element name="distant_metastasis_pathologic_spread" nillable="true">
			274	<xs:complexType>
			275	<xs:simpleContent>
			276	<xs:restriction base="utility:clinical_res_attributes">
149	<xs:element ref="cqcf:day_of_consent"/>		277	<xs:enumeration value="" />
			278	<xs:enumeration value="M0" />
			279	<xs:enumeration value="M1" />
			280	<xs:enumeration value="MX" />
			281	<xs:attribute name="cde" type="xs:string" default="3045439" />
			282	<xs:attribute name="xsd_ver" type="xs:string" default="2.1" />
			283	<xs:attribute name="tier" type="xs:string" default="1" />
			284	</xs:restriction>
			285	</xs:simpleContent>
			286	</xs:complexType>
			287	</xs:element>
150	<xs:element ref="cqcf:month_of_consent"/>	<>	289	<xs:element name="lymphnodes_examined_prior_presentation">
			290	<xs:complexType mixed="true">
			291	<xs:simpleContent>
151	<xs:element ref="cqcf:year_of_consent"/>		292	<xs:extension base="utility:yes_or_no">
			293	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			294	<xs:attribute name="cde" type="xs:string" default="2200396" />
			295	<xs:attribute name="xsd_ver" type="xs:string" default="2.1" />
			296	<xs:attribute name="tier" type="xs:string" default="1" />
			297	</xs:extension>
			298	</xs:simpleContent>
			299	</xs:complexType>
152	</xs:sequence>		300	</xs:element>
		<>	302	<xs:element name="number_of_lymphnodes_examined" nillable="true">
			303	<xs:complexType mixed="true">
			304	<xs:simpleContent>
			305	<xs:restriction base="utility:clinical_res_attributes">
153	<xs:element ref="cqcf:days_to_consent"/>		306	<xs:attribute name="cde" type="xs:string" default="3" />
			307	<xs:attribute name="xsd_ver" type="xs:string" default="2.1" />
			308	<xs:attribute name="tier" type="xs:string" default="1" />
154	</xs:choice>		309	</xs:restriction>
			310	</xs:simpleContent>
			311	</xs:complexType>
			312	</xs:element>
		<>	314	<xs:element name="number_of_lymphnodes_positive" nillable="true">
			315	<xs:complexType mixed="true">
			316	<xs:simpleContent>
			317	<xs:restriction base="utility:clinical_res_attributes">
			318	<xs:attribute name="cde" type="xs:string" default="89" />
			319	<xs:attribute name="xsd_ver" type="xs:string" default="2.1" />
			320	<xs:attribute name="tier" type="xs:string" default="1" />
155	<xs:choice>		321	</xs:restriction>
			322	</xs:simpleContent>
			323	</xs:complexType>
156	<xs:sequence>		324	</xs:element>
		<>	326	<xs:element name="erythrocyte_sedimentation_rate_result" nillable="true">
			327	<xs:complexType>
			328	<xs:simpleContent>
			329	<xs:restriction base="utility:clinical_res_attributes">
			330	<xs:enumeration value="" />
157	<xs:element ref="shared:day_of_death"/>		331	<xs:enumeration value="Elevated" />
158	<xs:element ref="shared:month_of_death"/>		332	<xs:enumeration value="Normal" />
			333	<xs:attribute name="cde" type="xs:string" default="3104952" />
159	<xs:element ref="shared:year_of_death"/>		334	<xs:attribute name="xsd_ver" type="xs:string" default="2.1" />
			335	<xs:attribute name="tier" type="xs:string" default="1" />
			336	</xs:restriction>
			337	</xs:simpleContent>
			338	</xs:complexType>
160	</xs:sequence>		339	</xs:element>
		<>	341	<xs:element name="white_cell_count_result" nillable="true">
			342	<xs:complexType>
			343	<xs:simpleContent>
			344	<xs:restriction base="utility:clinical_res_attributes">
			345	<xs:enumeration value="" />
161	<xs:element ref="shared:days_to_death"/>		346	<xs:enumeration value="Elevated" />
			347	<xs:enumeration value="Normal" />
			348	<xs:enumeration value="Low" />
			349	<xs:attribute name="cde" type="xs:string" default="3104948" />
			350	<xs:attribute name="xsd_ver" type="xs:string" default="2.1" />
			351	<xs:attribute name="tier" type="xs:string" default="1" />
162	</xs:choice>		352	</xs:restriction>
			353	</xs:simpleContent>
			354	</xs:complexType>
			355	</xs:element>
		<>	357	<xs:element name="platelet_qualitative_result" nillable="true">
			358	<xs:complexType>
			359	<xs:simpleContent>
			360	<xs:restriction base="utility:clinical_res_attributes">
			361	<xs:enumeration value="" />
			362	<xs:enumeration value="Elevated" />
			363	<xs:enumeration value="Normal" />
			364	<xs:enumeration value="Low" />
			365	<xs:attribute name="cde" type="xs:string" default="3104944" />
			366	<xs:attribute name="xsd_ver" type="xs:string" default="2.1" />
			367	<xs:attribute name="tier" type="xs:string" default="1" />
163	</xs:choice>		368	</xs:restriction>
			369	</xs:simpleContent>
			370	</xs:complexType>
			371	</xs:element>
		<>	373	<xs:element name="hemoglobin_result" nillable="true">
			374	<xs:complexType>
			375	<xs:simpleContent>
			376	<xs:restriction base="utility:clinical_res_attributes">
			377	<xs:enumeration value="" />
			378	<xs:enumeration value="Elevated" />
			379	<xs:enumeration value="Normal" />
			380	<xs:enumeration value="Low" />
			381	<xs:attribute name="cde" type="xs:string" default="3113466" />
164	<xs:element ref="cqcf:diagnosis_subtype"/>		382	<xs:attribute name="xsd_ver" type="xs:string" default="2.1" />
165	<xs:element ref="shared:prior_diagnosis"/>		383	<xs:attribute name="tier" type="xs:string" default="1" />
			384	</xs:restriction>
			385	</xs:simpleContent>
			386	</xs:complexType>
			387	</xs:element>
166	<xs:element ref="cqcf:normal_tissue_anatomic_site"/>	<>	389	<xs:element name="serum_calcium_result" nillable="true">
			390	<xs:complexType>
			391	<xs:simpleContent>
167	<xs:element ref="cqcf:normal_tissue_proximity"/>		392	<xs:restriction base="utility:clinical_res_attributes">
			393	<xs:enumeration value="" />
168	<xs:element ref="cqcf:tumor_type"/>		394	<xs:enumeration value="Elevated" />
			395	<xs:enumeration value="Normal" />
			396	<xs:enumeration value="Low" />
			397	<xs:attribute name="cde" type="xs:string" default="3113470" />
			398	<xs:attribute name="xsd_ver" type="xs:string" default="2.1" />
169	<xs:element ref="cqcf:histological_subtype" minOccurs="0"/>		399	<xs:attribute name="tier" type="xs:string" default="1" />
			400	</xs:restriction>
			401	</xs:simpleContent>
			402	</xs:complexType>
			403	</xs:element>
170	<xs:element ref="cqcf:other_anatomic_site" minOccurs="0"/>	<>	405	<xs:element name="lactate_dehydrogenase_result" nillable="true">
			406	<xs:complexType>
			407	<xs:simpleContent>
			408	<xs:restriction base="utility:clinical_res_attributes">
171	<xs:element ref="cqcf:country"/>		409	<xs:enumeration value="" />
			410	<xs:enumeration value="Elevated" />
			411	<xs:enumeration value="Normal" />
			412	<xs:attribute name="cde" type="xs:string" default="3113468" />
			413	<xs:attribute name="xsd_ver" type="xs:string" default="2.1" />
			414	<xs:attribute name="tier" type="xs:string" default="1" />
			415	</xs:restriction>
			416	</xs:simpleContent>
			417	</xs:complexType>
172	</xs:sequence>		418	</xs:element>
		-+	420	<xs:element name="laterality" nillable="true">
			421	<xs:complexType>
			422	<xs:simpleContent>
			423	<xs:restriction base="utility:clinical_res_attributes">
			424	<xs:enumeration value="" />
			425	<xs:enumeration value="Right" />
			426	<xs:enumeration value="Left" />
			427	<xs:enumeration value="Bilateral" />
			428	<xs:attribute name="cde" type="xs:string" default="827" />
			429	<xs:attribute name="xsd_ver" type="xs:string" default="2.1" />
			430	<xs:attribute name="tier" type="xs:string" default="1" />
			431	</xs:restriction>
			432	</xs:simpleContent>
		-+	451	<xs:element name="tumor_stage" nillable="true">
			452	<xs:complexType>
			453	<xs:simpleContent>
			454	<xs:restriction base="utility:clinical_res_attributes">
			455	<xs:enumeration value="" />
			456	<xs:enumeration value="Stage I" />
			457	<xs:enumeration value="Stage II" />
			458	<xs:enumeration value="Stage III" />
			459	<xs:enumeration value="Stage IV" />
			460	<xs:attribute name="cde" type="xs:string" default="3065862" />
			461	<xs:attribute name="xsd_ver" type="xs:string" default="1.11" />
			462	<xs:attribute name="tier" type="xs:string" default="1" />
			463	</xs:restriction>
			464	</xs:simpleContent>
			465	</xs:complexType>
			466	</xs:element>

   
File: TCGA_BCR.KIRP_Clinical_FollowUp_v1.0.xsd  

1	<?xml version="1.0" encoding="utf-8" ?>	+-
4	<xs:schema elementFormDefault="qualified" version="2.5.0"	+-
5	xmlns:xs="http://www.w3.org/2001/XMLSchema"
6	xmlns:shared="http://tcga.nci/bcr/xml/clinical/shared/2.5"
7	xmlns:utility="http://tcga.nci/bcr/xml/utility/2.5"
8	xmlns:admin="http://tcga.nci/bcr/xml/administration/2.5"
9	xmlns="http://tcga.nci/bcr/xml/clinical/kirp/followup/2.5/1.0"
10	targetNamespace="http://tcga.nci/bcr/xml/clinical/kirp/followup/2.5/1.0"
11	xmlns:jaxb="http://java.sun.com/xml/ns/jaxb" jaxb:version="1.0" >
13	<xs:import schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/utility/2.5/TCGA_BCR.Utility.xsd" namespace="http://tcga.nci/bcr/xml/utility/2.5" />	+-
14	<xs:import schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/administration/2.5/TCGA_BCR.Administration.xsd" namespace="http://tcga.nci/bcr/xml/administration/2.5" />
15	<xs:import schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/shared/2.5/TCGA_BCR.Shared_Clinical_Elements.xsd" namespace="http://tcga.nci/bcr/xml/clinical/shared/2.5" />
17	<xs:annotation>	+-
18	<xs:appinfo>
19	<jaxb:globalBindings generateIsSetMethod="true" />
20	<jaxb:schemaBindings>
21	<jaxb:package name="nci.tcga.bcr.xml.jaxb.clinical.kirp" />
22	</jaxb:schemaBindings>
23	</xs:appinfo>
24	</xs:annotation>
26	<xs:annotation>	+-
27	<xs:documentation xml:lang="en">Schema to define the elements of the TCGA Clinical Data Follow-up Form within the KIRP study.</xs:documentation>
28	</xs:annotation>
30	<xs:element name="follow_up_v1.0">	+-
31	<xs:complexType>
32	<xs:sequence>
33	<xs:element ref="shared:bcr_patient_barcode" />
34	<xs:element ref="shared:bcr_patient_uuid" />
35	<xs:element ref="shared:vital_status" />
36	<xs:choice>
37	<xs:sequence>
38	<xs:element ref="shared:day_of_last_followup" />
39	<xs:element ref="shared:month_of_last_followup" />
40	<xs:element ref="shared:year_of_last_followup" />
41	</xs:sequence>
42	<xs:element ref="shared:days_to_last_followup" />
43	</xs:choice>
44	<xs:choice>
45	<xs:sequence>
46	<xs:element ref="shared:day_of_death" />
47	<xs:element ref="shared:month_of_death" />
48	<xs:element ref="shared:year_of_death" />
49	</xs:sequence>
50	<xs:element ref="shared:days_to_death" />
51	</xs:choice>
52	<xs:choice>
53	<xs:sequence>
54	<xs:element ref="shared:day_of_new_tumor_event_after_initial_treatment" />
55	<xs:element ref="shared:month_of_new_tumor_event_after_initial_treatment" />
56	<xs:element ref="shared:year_of_new_tumor_event_after_initial_treatment" />
57	</xs:sequence>
58	<xs:element ref="shared:days_to_new_tumor_event_after_initial_treatment" />
59	</xs:choice>
60	<xs:element ref="shared:additional_surgery_locoregional_procedure" />
61	<xs:choice>
62	<xs:sequence>
63	<xs:element ref="shared:day_of_additional_surgery_locoregional_procedure" />
64	<xs:element ref="shared:month_of_additional_surgery_locoregional_procedure" />
65	<xs:element ref="shared:year_of_additional_surgery_locoregional_procedure" />
66	</xs:sequence>
67	<xs:element ref="shared:days_to_additional_surgery_locoregional_procedure" />
68	</xs:choice>
69	<xs:element ref="shared:person_neoplasm_cancer_status" />
70	<xs:element ref="shared:additional_radiation_therapy" />
71	<xs:element ref="shared:targeted_molecular_therapy" />
72	<xs:element ref="shared:additional_pharmaceutical_therapy" />
73	<xs:element ref="shared:additional_surgery_metastatic_procedure" />
74	<xs:choice>
75	<xs:sequence>
76	<xs:element ref="shared:day_of_additional_surgery_metastatic_procedure" />
77	<xs:element ref="shared:month_of_additional_surgery_metastatic_procedure" />
78	<xs:element ref="shared:year_of_additional_surgery_metastatic_procedure" />
79	</xs:sequence>
80	<xs:element ref="shared:days_to_additional_surgery_metastatic_procedure" />
81	</xs:choice>
82	<xs:choice>
83	<xs:sequence>
84	<xs:element ref="shared:day_of_form_completion" />
85	<xs:element ref="shared:month_of_form_completion" />
86	<xs:element ref="shared:year_of_form_completion" />
87	</xs:sequence>
88	<xs:element ref="shared:days_to_form_completion" />
89	</xs:choice>
91	<xs:element ref="shared:followup_case_report_form_submission_reason" />	+-
94	<xs:element ref="shared:karnofsky_performance_score" />	+-
95	<xs:element ref="shared:eastern_cancer_oncology_group" />
96	<xs:element ref="shared:performance_status_scale_timing" />
97	</xs:sequence>
98	<xs:attribute name="version" type="xs:string" default="1.0" use="optional"/>
99	</xs:complexType>
100	</xs:element>
101	</xs:schema>

   
File: TCGA_BCR.LAML_Clinical.xsd  

4	<xs:schema elementFormDefault="qualified" version="2.5.0"	<>	4	<xs:schema elementFormDefault="qualified" version="2.4.4"
6	xmlns:utility="http://tcga.nci/bcr/xml/utility/2.5"	<>	6	xmlns:utility="http://tcga.nci/bcr/xml/utility/2.4"
7	xmlns:admin="http://tcga.nci/bcr/xml/administration/2.5"		7	xmlns:admin="http://tcga.nci/bcr/xml/administration/2.4"
8	xmlns:shared="http://tcga.nci/bcr/xml/clinical/shared/2.5"		8	xmlns:shared="http://tcga.nci/bcr/xml/clinical/shared/2.4"
9	xmlns:laml_shared="http://tcga.nci/bcr/xml/clinical/laml/shared/2.5"
10	xmlns:rad="http://tcga.nci/bcr/xml/clinical/radiation/2.5"		9	xmlns:rad="http://tcga.nci/bcr/xml/clinical/radiation/2.4"
11	xmlns:rx="http://tcga.nci/bcr/xml/clinical/pharmaceutical/2.5"		10	xmlns:rx="http://tcga.nci/bcr/xml/clinical/pharmaceutical/2.4"
12	xmlns:cqcf="http://tcga.nci/bcr/xml/clinical/cqcf/2.5"
13	xmlns:follow_up_v2.0="http://tcga.nci/bcr/xml/clinical/laml/followup/2.5/2.0"
14	xmlns="http://tcga.nci/bcr/xml/clinical/laml/2.5"		11	xmlns="http://tcga.nci/bcr/xml/clinical/laml/2.4"
15	targetNamespace="http://tcga.nci/bcr/xml/clinical/laml/2.5"		12	targetNamespace="http://tcga.nci/bcr/xml/clinical/laml/2.4"
31	<xs:import namespace="http://tcga.nci/bcr/xml/utility/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/utility/2.5/TCGA_BCR.Utility.xsd" />	<>	28	<xs:import namespace="http://tcga.nci/bcr/xml/utility/2.4" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/utility/2.4/TCGA_BCR.Utility.xsd" />
32	<xs:import namespace="http://tcga.nci/bcr/xml/administration/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/administration/2.5/TCGA_BCR.Administration.xsd" />		29	<xs:import namespace="http://tcga.nci/bcr/xml/administration/2.4" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/administration/2.4/TCGA_BCR.Administration.xsd" />
33	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/shared/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/shared/2.5/TCGA_BCR.Shared_Clinical_Elements.xsd" />		30	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/shared/2.4" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/shared/2.4/TCGA_BCR.Shared_Clinical_Elements.xsd" />
34	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/radiation/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/radiation/2.5/TCGA_BCR.Radiation.xsd" />		31	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/radiation/2.4" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/radiation/2.4/TCGA_BCR.Radiation.xsd" />
35	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/pharmaceutical/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/pharmaceutical/2.5/TCGA_BCR.Pharmaceutical.xsd" />		32	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/pharmaceutical/2.4" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/pharmaceutical/2.4/TCGA_BCR.Pharmaceutical.xsd" />
36	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/cqcf/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/cqcf/2.5/TCGA_BCR.CQCF.xsd" />
37	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/laml/shared/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/laml/shared/2.5/TCGA_BCR.LAML_Clinical_Shared_Datatypes.xsd" />
38	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/laml/followup/2.5/2.0" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/laml/followup/2.5/TCGA_BCR.LAML_Clinical_FollowUp_v2.0.xsd" />
47	<xs:attribute name="schemaVersion" type="xs:decimal" use="required" fixed="2.5"/>	<>	41	<xs:attribute name="schemaVersion" type="xs:decimal" use="required" fixed="2.4"/>
172	<xs:element ref="shared:karnofsky_performance_score" />	<>	166	<xs:element ref="karnofsky_performance_score" />
173	<xs:element ref="shared:eastern_cancer_oncology_group" />		167	<xs:element ref="performance_status_assessment_eastern_cooperative_oncology_group_scale" />
186	<xs:element ref="follow_ups" />	+-
189	<xs:element ref="clinical_cqcf" />	+-
191	</xs:sequence>	+-
192	</xs:complexType>
193	</xs:element>
195	<xs:element name="follow_ups">	+-
196	<xs:annotation>
197	<xs:documentation xml:lang="en">We are using namespaces and version numbers to distinguish one version of followup from another.</xs:documentation>
198	</xs:annotation>
199	<xs:complexType>
200	<xs:sequence>
201	<xs:element ref="follow_up_v2.0:follow_up_v2.0" minOccurs="0" maxOccurs="unbounded" />
202	</xs:sequence>
203	</xs:complexType>
204	</xs:element>
206	<xs:element name="clinical_cqcf">	+-
207	<xs:annotation>
208	<xs:documentation xml:lang="en">This section is currently under development.</xs:documentation>
209	</xs:annotation>
210	<xs:complexType>
211	<xs:sequence>
1010	<xs:attribute name="cde" type="xs:string" default="3121628" />	<>	979	<xs:attribute name="cde" type="xs:string" default="3121483" />
1022	<xs:attribute name="cde" type="xs:string" default="3151753" />	<>	991	<xs:attribute name="cde" type="xs:string" default="3121491" />
1029		<>	998	<xs:element name="karnofsky_performance_score" nillable="true">
			999	<xs:complexType>
			1000	<xs:simpleContent>
			1001	<xs:restriction base="utility:clinical_res_attributes">
			1002	<xs:enumeration value="" />
			1003	<xs:enumeration value="0" />
			1004	<xs:enumeration value="10" />
			1005	<xs:enumeration value="20" />
			1006	<xs:enumeration value="30" />
			1007	<xs:enumeration value="40" />
			1008	<xs:enumeration value="50" />
			1009	<xs:enumeration value="60" />
			1010	<xs:enumeration value="70" />
			1011	<xs:enumeration value="80" />
			1012	<xs:enumeration value="90" />
			1013	<xs:enumeration value="100" />
			1014	<xs:attribute name="cde" type="xs:string" default="2003853" />
			1015	<xs:attribute name="xsd_ver" type="xs:string" default="1.8" />
			1016	<xs:attribute name="tier" type="xs:string" default="2" />
			1017	</xs:restriction>
			1018	</xs:simpleContent>
			1019	</xs:complexType>
			1020	</xs:element>
			1021	<xs:element name="performance_status_assessment_eastern_cooperative_oncology_group_scale" nillable="true">
			1022	<xs:complexType mixed="true">
			1023	<xs:simpleContent>
			1024	<xs:restriction base="utility:clinical_res_attributes">
			1025	<xs:enumeration value="" />
			1026	<xs:enumeration value="0" />
			1027	<xs:enumeration value="1" />
			1028	<xs:enumeration value="2" />
			1029	<xs:enumeration value="3" />
			1030	<xs:enumeration value="4" />
			1031	<xs:enumeration value="5" />
			1032	<xs:attribute name="cde" type="xs:string" default="88" />
			1033	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			1034	<xs:attribute name="tier" type="xs:string" default="2" />
			1035	</xs:restriction>
			1036	</xs:simpleContent>
			1037	</xs:complexType>
			1038	</xs:element>

   
File: TCGA_BCR.LAML_Clinical_FollowUp_v2.0.xsd  

1	<?xml version="1.0" encoding="utf-8" ?>	+-
4	<xs:schema elementFormDefault="qualified" version="2.5.0"	+-
5	xmlns:xs="http://www.w3.org/2001/XMLSchema"
6	xmlns:shared="http://tcga.nci/bcr/xml/clinical/shared/2.5"
7	xmlns:blca_shared="http://tcga.nci/bcr/xml/clinical/laml/shared/2.5"
8	xmlns="http://tcga.nci/bcr/xml/clinical/laml/followup/2.5/2.0"
9	targetNamespace="http://tcga.nci/bcr/xml/clinical/laml/followup/2.5/2.0"
10	xmlns:jaxb="http://java.sun.com/xml/ns/jaxb" jaxb:version="1.0" >
12	<xs:annotation>	+-
13	<xs:appinfo>
14	<jaxb:globalBindings generateIsSetMethod="true" />
16	<jaxb:schemaBindings>	+-
17	<jaxb:package name="nci.tcga.bcr.xml.jaxb.clinical.laml" />
18	</jaxb:schemaBindings>
19	</xs:appinfo>
20	</xs:annotation>
22	<xs:annotation>	+-
23	<xs:documentation xml:lang="en">Schema to define the elements of the TCGA Clinical Data Follow-up Form within the LAML study.</xs:documentation>
24	</xs:annotation>
26	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/shared/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/shared/2.5/TCGA_BCR.Shared_Clinical_Elements.xsd" />	+-
27	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/laml/shared/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/laml/shared/2.5/TCGA_BCR.LAML_Clinical_Shared_Datatypes.xsd" />
29	<xs:element name="follow_up_v2.0">	+-
30	<xs:complexType>
31	<xs:sequence>
32	<xs:element ref="shared:bcr_patient_barcode" />
33	<xs:element ref="shared:bcr_patient_uuid" />
35	<xs:choice>	+-
36	<xs:sequence>
37	<xs:element ref="shared:day_of_form_completion" />
38	<xs:element ref="shared:month_of_form_completion" />
39	<xs:element ref="shared:year_of_form_completion" />
40	</xs:sequence>
42	<xs:element ref="shared:days_to_form_completion" />	+-
43	</xs:choice>
44	</xs:sequence>
46	<xs:attribute name="version" type="xs:string" default="2.0" use="optional"/>	+-
47	</xs:complexType>
48	</xs:element>
49	</xs:schema>

   
File: TCGA_BCR.LAML_Clinical_Shared_Datatypes.xsd  

1	<?xml version="1.0" encoding="utf-8" ?>	+-
4	<xs:schema elementFormDefault="qualified" version="2.5.0"	+-
5	xmlns:xs="http://www.w3.org/2001/XMLSchema"
6	xmlns:utility="http://tcga.nci/bcr/xml/utility/2.5"
7	xmlns="http://tcga.nci/bcr/xml/clinical/laml/shared/2.5"
8	targetNamespace="http://tcga.nci/bcr/xml/clinical/laml/shared/2.5">
10	<xs:import namespace="http://tcga.nci/bcr/xml/utility/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/utility/2.5/TCGA_BCR.Utility.xsd" />	+-
13	</xs:schema>	+-

   
File: TCGA_BCR.LGG_Clinical.xsd  

4	<xs:schema xmlns:xs="http://www.w3.org/2001/XMLSchema" xmlns:utility="http://tcga.nci/bcr/xml/utility/2.5" xmlns:admin="http://tcga.nci/bcr/xml/administration/2.5" xmlns:shared="http://tcga.nci/bcr/xml/clinical/shared/2.5" xmlns:rad="http://tcga.nci/bcr/xml/clinical/radiation/2.5" xmlns:rx="http://tcga.nci/bcr/xml/clinical/pharmaceutical/2.5" xmlns:cqcf="http://tcga.nci/bcr/xml/clinical/cqcf/2.5" xmlns:follow_up_v1.0="http://tcga.nci/bcr/xml/clinical/lgg/followup/2.5/1.0" xmlns="http://tcga.nci/bcr/xml/clinical/lgg/2.5" xmlns:jaxb="http://java.sun.com/xml/ns/jaxb" targetNamespace="http://tcga.nci/bcr/xml/clinical/lgg/2.5" elementFormDefault="qualified" version="2.5.0" jaxb:version="1.0">	<>	3
			4	<xs:schema elementFormDefault="qualified" version="2.4.4"
			5	xmlns:xs="http://www.w3.org/2001/XMLSchema"
			6	xmlns:utility="http://tcga.nci/bcr/xml/utility/2.4"
			7	xmlns:admin="http://tcga.nci/bcr/xml/administration/2.4"
			8	xmlns:shared="http://tcga.nci/bcr/xml/clinical/shared/2.4"
			9	xmlns:rad="http://tcga.nci/bcr/xml/clinical/radiation/2.4"
			10	xmlns:rx="http://tcga.nci/bcr/xml/clinical/pharmaceutical/2.4"
			11	xmlns="http://tcga.nci/bcr/xml/clinical/lgg/2.4"
			12	targetNamespace="http://tcga.nci/bcr/xml/clinical/lgg/2.4"
			13	xmlns:jaxb="http://java.sun.com/xml/ns/jaxb" jaxb:version="1.0">
16	<xs:import namespace="http://tcga.nci/bcr/xml/utility/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/utility/2.5/TCGA_BCR.Utility.xsd"/>	<>	28	<xs:import namespace="http://tcga.nci/bcr/xml/utility/2.4" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/utility/2.4/TCGA_BCR.Utility.xsd" />
17	<xs:import namespace="http://tcga.nci/bcr/xml/administration/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/administration/2.5/TCGA_BCR.Administration.xsd"/>		29	<xs:import namespace="http://tcga.nci/bcr/xml/administration/2.4" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/administration/2.4/TCGA_BCR.Administration.xsd" />
18	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/shared/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/shared/2.5/TCGA_BCR.Shared_Clinical_Elements.xsd"/>		30	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/shared/2.4" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/shared/2.4/TCGA_BCR.Shared_Clinical_Elements.xsd" />
19	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/radiation/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/radiation/2.5/TCGA_BCR.Radiation.xsd"/>		31	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/radiation/2.4" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/radiation/2.4/TCGA_BCR.Radiation.xsd" />
20	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/pharmaceutical/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/pharmaceutical/2.5/TCGA_BCR.Pharmaceutical.xsd"/>		32	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/pharmaceutical/2.4" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/pharmaceutical/2.4/TCGA_BCR.Pharmaceutical.xsd" />
21	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/cqcf/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/cqcf/2.5/TCGA_BCR.CQCF.xsd"/>		33
22	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/lgg/followup/2.5/1.0" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/lgg/followup/2.5/TCGA_BCR.LGG_Clinical_FollowUp_v1.0.xsd"/>
29	<xs:attribute name="schemaVersion" type="xs:decimal" use="required" fixed="2.5"/>	<>	41	<xs:attribute name="schemaVersion" type="xs:decimal" use="required" fixed="2.4"/>
93	<xs:element ref="shared:person_neoplasm_cancer_status"/>	<>	118
		-+	130	<xs:element ref="shared:person_neoplasm_cancer_status" />
138	<xs:element ref="shared:karnofsky_performance_score"/>	<>	167	<xs:element ref="karnofsky_performance_score" />
139	<xs:element ref="shared:eastern_cancer_oncology_group"/>		168	<xs:element ref="eastern_cancer_oncology_group" />
150	<xs:element ref="clinical_cqcf"/>	+-
151	<xs:element name="follow_ups">
152	<xs:annotation>
153	<xs:documentation>We are using namespaces and version numbers to distinguish one version of followup from another.</xs:documentation>
154	</xs:annotation>
155	<xs:complexType>
156	<xs:sequence>
157	<xs:element ref="follow_up_v1.0:follow_up_v1.0" minOccurs="0" maxOccurs="unbounded"/>
161	</xs:sequence>	<>	185
162	</xs:complexType>
163	</xs:element>
164	<xs:element name="clinical_cqcf">
165	<xs:complexType>
166	<xs:sequence>
167	<xs:element ref="cqcf:frozen_specimen_anatomic_site"/>
168	<xs:element ref="cqcf:history_of_prior_malignancy"/>
169	<xs:element ref="cqcf:history_of_neoadjuvant_treatment"/>
170	<xs:element ref="cqcf:consent_or_death_status"/>
171	<xs:choice>
172	<xs:choice>
173	<xs:sequence>
174	<xs:element ref="cqcf:day_of_consent"/>
175	<xs:element ref="cqcf:month_of_consent"/>
176	<xs:element ref="cqcf:year_of_consent"/>
177	</xs:sequence>
178	<xs:element ref="cqcf:days_to_consent"/>
179	</xs:choice>
180	<xs:choice>
181	<xs:sequence>
182	<xs:element ref="shared:day_of_death"/>
183	<xs:element ref="shared:month_of_death"/>
184	<xs:element ref="shared:year_of_death"/>
185	</xs:sequence>
186	<xs:element ref="shared:days_to_death"/>
187	</xs:choice>
188	</xs:choice>
189	<xs:element ref="cqcf:prior_head_radiation_therapy"/>
190	<xs:element ref="cqcf:diagnosis_subtype"/>
191	<xs:element ref="shared:prior_diagnosis"/>
192	<xs:element ref="cqcf:normal_tissue_anatomic_site"/>
193	<xs:element ref="cqcf:normal_tissue_proximity"/>
194	<xs:element ref="cqcf:tumor_type"/>
195	<xs:element ref="cqcf:histological_subtype" minOccurs="0"/>
196	<xs:element ref="cqcf:other_anatomic_site" minOccurs="0"/>
197	<xs:element ref="cqcf:country"/>
198	</xs:sequence>
199	</xs:complexType>
200	</xs:element>
		-+	249	<xs:element name="primary_therapy_outcome_success" nillable="true">
			250	<xs:complexType>
			251	<xs:simpleContent>
			252	<xs:restriction base="utility:clinical_res_attributes">
			253	<xs:enumeration value="" />
			254	<xs:enumeration value="PROGRESSIVE DISEASE" />
			255	<xs:enumeration value="STABLE DISEASE" />
			256	<xs:enumeration value="PARTIAL RESPONSE" />
			257	<xs:enumeration value="COMPLETE RESPONSE" />
			258	<xs:attribute name="cde" type="xs:string" default="2786727" />
			259	<xs:attribute name="xsd_ver" type="xs:string" default="1.11" />
			260	<xs:attribute name="tier" type="xs:string" default="2" />
			261	</xs:restriction>
			262	</xs:simpleContent>
			263	</xs:complexType>
			264	</xs:element>
		-+	266	<xs:element name="karnofsky_performance_score">
			267	<xs:complexType>
			268	<xs:simpleContent>
			269	<xs:restriction base="utility:clinical_res_attributes">
			270	<xs:enumeration value="" />
			271	<xs:enumeration value="0" />
			272	<xs:enumeration value="10" />
			273	<xs:enumeration value="20" />
			274	<xs:enumeration value="30" />
			275	<xs:enumeration value="40" />
			276	<xs:enumeration value="50" />
			277	<xs:enumeration value="60" />
			278	<xs:enumeration value="70" />
			279	<xs:enumeration value="80" />
			280	<xs:enumeration value="90" />
			281	<xs:enumeration value="100" />
			282	<xs:attribute name="cde" type="xs:string" default="2003853" />
			283	<xs:attribute name="xsd_ver" type="xs:string" default="1.8" />
			284	<xs:attribute name="tier" type="xs:string" default="2" />
			285	</xs:restriction>
			286	</xs:simpleContent>
			287	</xs:complexType>
			288	</xs:element>
		-+	290	<xs:element name="eastern_cancer_oncology_group">
			291	<xs:complexType>
			292	<xs:simpleContent>
			293	<xs:restriction base="utility:clinical_res_attributes">
			294	<xs:enumeration value="" />
			295	<xs:enumeration value="0" />
			296	<xs:enumeration value="1" />
			297	<xs:enumeration value="2" />
			298	<xs:enumeration value="3" />
			299	<xs:enumeration value="4" />
			300	<xs:attribute name="cde" type="xs:string" default="88" />
			301	<xs:attribute name="xsd_ver" type="xs:string" default="1.9" />
			302	<xs:attribute name="tier" type="xs:string" default="2" />
			303	</xs:restriction>
			304	</xs:simpleContent>
			305	</xs:complexType>
			306	</xs:element>
533	<xs:enumeration value="Supratentorial, Frontal Lobe"/>	<>	604	<xs:enumeration value="Supratentorial Frontal Lobe" />
534	<xs:enumeration value="Supratentorial, Temporal Lobe"/>		605	<xs:enumeration value="Supratentorial Temporal Lobe" />
535	<xs:enumeration value="Supratentorial, Parietal Lobe"/>		606	<xs:enumeration value="Supratentorial Parietal Lobe" />
536	<xs:enumeration value="Supratentorial, Occipital Lobe"/>		607	<xs:enumeration value="Supratentorial Occipital Lobe" />
537	<xs:enumeration value="Supratentorial, Not Otherwise Specified"/>		608	<xs:enumeration value="Supratentorial-Not Otherwise Specified" />
538	<xs:enumeration value="Posterior Fossa, Cerebellum"/>		609	<xs:enumeration value="Posterior Fossa Cerebellum" />
539	<xs:enumeration value="Posterior Fossa, Brain Stem"/>		610	<xs:enumeration value="Posterior Fossa Brain Stem" />
555	<xs:enumeration value="Deep Gray (e.g.basal ganglia, thalamus)"/>	<>	627	<xs:enumeration value="Deep Gray" />
556	<xs:enumeration value="Not listed in Medical Record"/>		628	<xs:enumeration value="Not Listed on Medical Record" />

   
File: TCGA_BCR.LGG_Clinical_FollowUp_v1.0.xsd  

1	<?xml version="1.0" encoding="utf-8" ?>	+-
4	<xs:schema elementFormDefault="qualified" version="2.5.0"	+-
5	xmlns:xs="http://www.w3.org/2001/XMLSchema"
6	xmlns:shared="http://tcga.nci/bcr/xml/clinical/shared/2.5"
7	xmlns:utility="http://tcga.nci/bcr/xml/utility/2.5"
8	xmlns:admin="http://tcga.nci/bcr/xml/administration/2.5"
9	xmlns="http://tcga.nci/bcr/xml/clinical/lgg/followup/2.5/1.0"
10	targetNamespace="http://tcga.nci/bcr/xml/clinical/lgg/followup/2.5/1.0"
11	xmlns:jaxb="http://java.sun.com/xml/ns/jaxb" jaxb:version="1.0" >
13	<xs:import schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/utility/2.5/TCGA_BCR.Utility.xsd" namespace="http://tcga.nci/bcr/xml/utility/2.5" />	+-
14	<xs:import schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/administration/2.5/TCGA_BCR.Administration.xsd" namespace="http://tcga.nci/bcr/xml/administration/2.5" />
15	<xs:import schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/shared/2.5/TCGA_BCR.Shared_Clinical_Elements.xsd" namespace="http://tcga.nci/bcr/xml/clinical/shared/2.5" />
17	<xs:annotation>	+-
18	<xs:appinfo>
19	<jaxb:globalBindings generateIsSetMethod="true" />
20	<jaxb:schemaBindings>
21	<jaxb:package name="nci.tcga.bcr.xml.jaxb.clinical.lgg" />
22	</jaxb:schemaBindings>
23	</xs:appinfo>
24	</xs:annotation>
26	<xs:annotation>	+-
27	<xs:documentation xml:lang="en">Schema to define the elements of the TCGA Clinical Data Follow-up Form within the LGG study.</xs:documentation>
28	</xs:annotation>
30	<xs:element name="follow_up_v1.0">	+-
31	<xs:complexType>
32	<xs:sequence>
33	<xs:element ref="shared:bcr_patient_barcode" />
34	<xs:element ref="shared:bcr_patient_uuid" />
35	<xs:element ref="shared:vital_status" />
36	<xs:choice>
37	<xs:sequence>
38	<xs:element ref="shared:day_of_last_followup" />
39	<xs:element ref="shared:month_of_last_followup" />
40	<xs:element ref="shared:year_of_last_followup" />
41	</xs:sequence>
42	<xs:element ref="shared:days_to_last_followup" />
43	</xs:choice>
44	<xs:choice>
45	<xs:sequence>
46	<xs:element ref="shared:day_of_death" />
47	<xs:element ref="shared:month_of_death" />
48	<xs:element ref="shared:year_of_death" />
49	</xs:sequence>
50	<xs:element ref="shared:days_to_death" />
51	</xs:choice>
52	<xs:element ref="shared:new_tumor_event_after_initial_treatment" />
53	<xs:choice>
54	<xs:sequence>
55	<xs:element ref="shared:day_of_new_tumor_event_after_initial_treatment" />
56	<xs:element ref="shared:month_of_new_tumor_event_after_initial_treatment" />
57	<xs:element ref="shared:year_of_new_tumor_event_after_initial_treatment" />
58	</xs:sequence>
59	<xs:element ref="shared:days_to_new_tumor_event_after_initial_treatment" />
60	</xs:choice>
61	<xs:element ref="shared:additional_surgery_locoregional_procedure" />
62	<xs:choice>
63	<xs:sequence>
64	<xs:element ref="shared:day_of_additional_surgery_locoregional_procedure" />
65	<xs:element ref="shared:month_of_additional_surgery_locoregional_procedure" />
66	<xs:element ref="shared:year_of_additional_surgery_locoregional_procedure" />
67	</xs:sequence>
68	<xs:element ref="shared:days_to_additional_surgery_locoregional_procedure" />
69	</xs:choice>
70	<xs:element ref="shared:person_neoplasm_cancer_status" />
71	<xs:element ref="shared:additional_pharmaceutical_therapy" />
72	<xs:element ref="shared:additional_radiation_therapy" />
73	<xs:choice>
74	<xs:sequence>
75	<xs:element ref="shared:day_of_form_completion" />
76	<xs:element ref="shared:month_of_form_completion" />
77	<xs:element ref="shared:year_of_form_completion" />
78	</xs:sequence>
79	<xs:element ref="shared:days_to_form_completion" />
80	</xs:choice>
82	<xs:element ref="shared:followup_case_report_form_submission_reason" />	+-
84	<xs:element ref="shared:karnofsky_performance_score" />	+-
85	<xs:element ref="shared:eastern_cancer_oncology_group" />
86	<xs:element ref="shared:performance_status_scale_timing" />
87	<xs:element ref="shared:followup_treatment_success" />
88	<xs:choice>
89	<xs:sequence>
90	<xs:element ref="shared:month_of_performance_status_follow_up_score" />
91	<xs:element ref="shared:day_of_performance_status_follow_up_score" />
92	<xs:element ref="shared:year_of_performance_status_follow_up_score" />
93	</xs:sequence>
94	<xs:element ref="shared:days_to_form_completion" />
95	</xs:choice>
96	<xs:element ref="shared:additional_surgery_metastatic_procedure" />
97	<xs:choice>
98	<xs:sequence>
99	<xs:element ref="shared:month_of_additional_surgery_metastatic_procedure" />
100	<xs:element ref="shared:day_of_additional_surgery_metastatic_procedure" />
101	<xs:element ref="shared:year_of_additional_surgery_metastatic_procedure" />
102	</xs:sequence>
103	<xs:element ref="shared:days_to_form_completion" />
104	</xs:choice>
105	</xs:sequence>
106	<xs:attribute name="version" type="xs:string" default="1.0" use="optional"/>
107	</xs:complexType>
108	</xs:element>
111	<xs:element name="followup_treatment_success" nillable="true">	+-
112	<xs:complexType mixed="true">
113	<xs:simpleContent>
114	<xs:restriction base="utility:clinical_res_attributes">
115	<xs:attribute name="cde" type="xs:string" default="3104050" />
116	<xs:attribute name="xsd_ver" type="xs:string" default="2.5" />
117	<xs:attribute name="tier" type="xs:string" default="2" />
118	</xs:restriction>
119	</xs:simpleContent>
120	</xs:complexType>
121	</xs:element>
123	<xs:element name="days_to_score_of_performance_status_scale_during_this_follow_up_period" nillable="true">	+-
124	<xs:complexType mixed="true">
125	<xs:simpleContent>
126	<xs:restriction base="utility:clinical_res_attributes">
127	<xs:attribute name="cde" type="xs:string" default="" />
128	<xs:attribute name="xsd_ver" type="xs:string" default="" />
129	<xs:attribute name="tier" type="xs:string" default="1" />
130	</xs:restriction>
131	</xs:simpleContent>
132	</xs:complexType>
133	</xs:element>
135	<xs:element name="days_to_additional_surgery_for_new_tumor_event_remote_resection" nillable="true">	+-
136	<xs:complexType mixed="true">
137	<xs:simpleContent>
138	<xs:restriction base="utility:clinical_res_attributes">
139	<xs:attribute name="cde" type="xs:string" default="" />
140	<xs:attribute name="xsd_ver" type="xs:string" default="" />
141	<xs:attribute name="tier" type="xs:string" default="1" />
142	</xs:restriction>
143	</xs:simpleContent>
144	</xs:complexType>
145	</xs:element>
147	</xs:schema>	+-

   
File: TCGA_BCR.LIHC_Clinical.xsd  

4	<xs:schema elementFormDefault="qualified" version="2.5.0"	<>	4	<xs:schema elementFormDefault="qualified" version="2.4.4"
6	xmlns:utility="http://tcga.nci/bcr/xml/utility/2.5"	<>	6	xmlns:utility="http://tcga.nci/bcr/xml/utility/2.4"
7	xmlns:admin="http://tcga.nci/bcr/xml/administration/2.5"		7	xmlns:admin="http://tcga.nci/bcr/xml/administration/2.4"
8	xmlns:shared="http://tcga.nci/bcr/xml/clinical/shared/2.5"		8	xmlns:shared="http://tcga.nci/bcr/xml/clinical/shared/2.4"
9	xmlns:rad="http://tcga.nci/bcr/xml/clinical/radiation/2.5"		9	xmlns:rad="http://tcga.nci/bcr/xml/clinical/radiation/2.4"
10	xmlns:rx="http://tcga.nci/bcr/xml/clinical/pharmaceutical/2.5"		10	xmlns:rx="http://tcga.nci/bcr/xml/clinical/pharmaceutical/2.4"
11	xmlns:cqcf="http://tcga.nci/bcr/xml/clinical/cqcf/2.5"
12	xmlns:follow_up_v1.0="http://tcga.nci/bcr/xml/clinical/lihc/followup/2.5/1.0"
13	xmlns:follow_up_v2.0="http://tcga.nci/bcr/xml/clinical/lihc/followup/2.5/2.0"
14	xmlns="http://tcga.nci/bcr/xml/clinical/lihc/2.5"		11	xmlns="http://tcga.nci/bcr/xml/clinical/lihc/2.4"
15	targetNamespace="http://tcga.nci/bcr/xml/clinical/lihc/2.5"		12	targetNamespace="http://tcga.nci/bcr/xml/clinical/lihc/2.4"
31	<xs:import namespace="http://tcga.nci/bcr/xml/utility/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/utility/2.5/TCGA_BCR.Utility.xsd" />	<>	28	<xs:import namespace="http://tcga.nci/bcr/xml/utility/2.4" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/utility/2.4/TCGA_BCR.Utility.xsd" />
32	<xs:import namespace="http://tcga.nci/bcr/xml/administration/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/administration/2.5/TCGA_BCR.Administration.xsd" />		29	<xs:import namespace="http://tcga.nci/bcr/xml/administration/2.4" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/administration/2.4/TCGA_BCR.Administration.xsd" />
33	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/shared/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/shared/2.5/TCGA_BCR.Shared_Clinical_Elements.xsd" />		30	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/shared/2.4" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/shared/2.4/TCGA_BCR.Shared_Clinical_Elements.xsd" />
34	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/radiation/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/radiation/2.5/TCGA_BCR.Radiation.xsd" />		31	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/radiation/2.4" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/radiation/2.4/TCGA_BCR.Radiation.xsd" />
35	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/pharmaceutical/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/pharmaceutical/2.5/TCGA_BCR.Pharmaceutical.xsd" />		32	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/pharmaceutical/2.4" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/pharmaceutical/2.4/TCGA_BCR.Pharmaceutical.xsd" />
36	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/cqcf/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/cqcf/2.5/TCGA_BCR.CQCF.xsd" />
37	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/lihc/shared/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/lihc/shared/2.5/TCGA_BCR.LIHC_Clinical_Shared_Datatypes.xsd" />
38	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/lihc/followup/2.5/1.0" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/lihc/followup/2.5/TCGA_BCR.LIHC_Clinical_FollowUp_v1.0.xsd" />
39	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/lihc/followup/2.5/2.0" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/lihc/followup/2.5/TCGA_BCR.LIHC_Clinical_FollowUp_v2.0.xsd" />
48	<xs:attribute name="schemaVersion" type="xs:decimal" use="required" fixed="2.5"/>	<>	41	<xs:attribute name="schemaVersion" type="xs:decimal" use="required" fixed="2.4"/>
55	<xs:element ref="shared:tissue_source_site" />	+-
56	<xs:element ref="shared:patient_id" />
57	<xs:element ref="shared:bcr_patient_barcode" />
58	<xs:element ref="shared:bcr_patient_uuid" />
59	<xs:element ref="shared:informed_consent_verified" />
60	<xs:element ref="shared:icd_o_3_site" />
61	<xs:element ref="shared:icd_o_3_histology" />
62	<xs:element ref="shared:icd_10" />
107	<xs:annotation>	+-
108	<xs:documentation xml:lang="en">
109	The Date for Last Known Alive was DEPRECATED.  It
110	was last placed on the TCGA Clinical Form 1.06.
111	</xs:documentation>
112	</xs:annotation>
139	<xs:element ref="histological_type" />	<>	116	<xs:element ref="neoplasm_histologic_type_name" />
153	<xs:element ref="shared:neoplasm_histologic_grade" />	<>	130	<xs:element ref="neoplasm_histologic_grade" />
154	<xs:element ref="shared:residual_tumor" />		131	<xs:element ref="surgical_margin_resection_status" />
155	<xs:element ref="shared:ajcc_cancer_staging_handbook_edition" />		132	<xs:element ref="american_joint_committee_on_cancer_publication_version_type" />
156	<xs:element ref="shared:ajcc_tumor_stage_code" />		133	<xs:element ref="american_joint_committee_on_cancer_tumor_stage_code" />
157	<xs:element ref="shared:ajcc_neoplasm_disease_lymph_node_stage" />		134	<xs:element ref="neoplasm_disease_lymph_node_stage_american_joint_committee_on_cancer_code" />
158	<xs:element ref="shared:ajcc_cancer_metastasis_stage_code" />		135	<xs:element ref="american_joint_committee_on_cancer_metastasis_stage_code" />
159	<xs:element ref="shared:ajcc_neoplasm_disease_stage" />		136	<xs:element ref="neoplasm_disease_stage_american_joint_committee_on_cancer_code" />
165	<xs:element ref="lab_procedure_platelet_result_specified_value" />	<>	142	<xs:element ref="laboratory_procedure_platelet_result_specified_value" />
		-+	159	<xs:element ref="performance_status_assessment_eastern_cooperative_oncology_group_scale" />
182	<xs:element ref="shared:eastern_cancer_oncology_group" />	<>	162	<xs:element ref="shared:bcr_patient_barcode" />
			163	<xs:element ref="shared:tissue_source_site" />
			164	<xs:element ref="shared:patient_id" />
			165	<xs:element ref="shared:bcr_patient_uuid" />
			166	<xs:element ref="shared:informed_consent_verified" />
			167	<xs:element ref="shared:icd_o_3_site" />
			168	<xs:element ref="shared:icd_o_3_histology" />
			169	<xs:element ref="shared:icd_10" />
198	<xs:element ref="follow_ups" />	+-
201	<xs:element ref="clinical_cqcf" />	+-
202	</xs:sequence>
203	</xs:complexType>
204	</xs:element>
206	<xs:element name="follow_ups">	+-
207	<xs:annotation>
208	<xs:documentation xml:lang="en">
209	We are using namespaces and version numbers to distinguish one version of followup from another.
210	</xs:documentation>
211	</xs:annotation>
212	<xs:complexType>
213	<xs:sequence>
214	<xs:element ref="follow_up_v1.0:follow_up_v1.0" minOccurs="0" maxOccurs="unbounded" />
215	<xs:element ref="follow_up_v2.0:follow_up_v2.0" minOccurs="0" maxOccurs="unbounded" />
216	</xs:sequence>
217	</xs:complexType>
218	</xs:element>
220	<xs:element name="clinical_cqcf">	+-
221	<xs:complexType>
222	<xs:sequence>
223	<xs:element ref="shared:anatomic_organ_subdivision"/>
224	<xs:element ref="cqcf:consent_or_death_status"/>
226	<xs:choice>	+-
227	<xs:choice>
228	<xs:sequence>
229	<xs:element ref="cqcf:day_of_consent"/>
230	<xs:element ref="cqcf:month_of_consent"/>
231	<xs:element ref="cqcf:year_of_consent"/>
232	</xs:sequence>
234	<xs:element ref="cqcf:days_to_consent"/>	+-
235	</xs:choice>
237	<xs:choice>	+-
238	<xs:sequence>
239	<xs:element ref="shared:day_of_death"/>
240	<xs:element ref="shared:month_of_death"/>
241	<xs:element ref="shared:year_of_death"/>
242	</xs:sequence>
244	<xs:element ref="shared:days_to_death"/>	+-
245	</xs:choice>
246	</xs:choice>
248	<xs:element ref="cqcf:diagnosis_subtype"/>	+-
249	<xs:element ref="shared:prior_diagnosis"/>
250	<xs:element ref="cqcf:history_of_neoadjuvant_treatment"/>
251	<xs:element ref="cqcf:normal_tissue_anatomic_site"/>
252	<xs:element ref="cqcf:normal_tissue_proximity"/>
253	<xs:element ref="cqcf:tumor_focality"/>
254	<xs:element ref="cqcf:tumor_type"/>
255	<xs:element ref="cqcf:other_diagnosis"/>
256	<xs:element ref="cqcf:histological_subtype" minOccurs="0"/>
257	<xs:element ref="cqcf:other_anatomic_site" minOccurs="0"/>
258	<xs:element ref="cqcf:country"/>
308	<xs:extension base="utility:integer_or_null">	<>	236	<xs:extension base="xs:integer">
328	<xs:enumeration value="None" />	<>	256	<xs:enumeration value="No History of Primary Risk Factors" />
329	<xs:enumeration value="Nonalcoholic Fatty Liver Disease" />		257	<xs:enumeration value="Non-Alcoholic Fatty Liver Disease" />
352	<xs:element name="histological_type" nillable="true">	<>	280	<xs:element name="neoplasm_histologic_type_name" nillable="true">
		-+	379	<xs:element name="neoplasm_histologic_grade" nillable="true">
			380	<xs:complexType mixed="true">
			381	<xs:simpleContent>
			382	<xs:restriction base="utility:clinical_res_attributes">
			383	<xs:enumeration value="" />
			384	<xs:enumeration value="G1" />
			385	<xs:enumeration value="G2" />
			386	<xs:enumeration value="G3" />
			387	<xs:enumeration value="G4" />
			388	<xs:enumeration value="GX" />
			389	<xs:attribute name="cde" type="xs:string" default="2785839" />
			390	<xs:attribute name="xsd_ver" type="xs:string" default="2.4" />
			391	<xs:attribute name="tier" type="xs:string" default="1" />
			392	</xs:restriction>
			393	</xs:simpleContent>
			394	</xs:complexType>
			395	</xs:element>
		-+	397	<xs:element name="surgical_margin_resection_status" nillable="true">
			398	<xs:complexType>
			399	<xs:simpleContent>
			400	<xs:restriction base="utility:clinical_res_attributes">
			401	<xs:enumeration value="" />
			402	<xs:enumeration value="RX" />
			403	<xs:enumeration value="R0" />
			404	<xs:enumeration value="R1" />
			405	<xs:enumeration value="R2" />
			406	<xs:attribute name="cde" type="xs:string" default="2608702" />
			407	<xs:attribute name="xsd_ver" type="xs:string" default="2.4" />
			408	<xs:attribute name="tier" type="xs:string" default="1" />
			409	</xs:restriction>
			410	</xs:simpleContent>
			411	</xs:complexType>
			412	</xs:element>
		-+	414	<xs:element name="american_joint_committee_on_cancer_publication_version_type" nillable="true">
			415	<xs:complexType>
			416	<xs:simpleContent>
			417	<xs:restriction base="utility:clinical_res_attributes">
			418	<xs:enumeration value="" />
			419	<xs:enumeration value="1st" />
			420	<xs:enumeration value="2nd" />
			421	<xs:enumeration value="3rd" />
			422	<xs:enumeration value="4th" />
			423	<xs:enumeration value="5th" />
			424	<xs:enumeration value="6th" />
			425	<xs:enumeration value="7th" />
			426	<xs:attribute name="cde" type="xs:string" default="2722309" />
			427	<xs:attribute name="xsd_ver" type="xs:string" default="2.4" />
			428	<xs:attribute name="tier" type="xs:string" default="1" />
			429	</xs:restriction>
			430	</xs:simpleContent>
			431	</xs:complexType>
			432	</xs:element>
		-+	434	<xs:element name="american_joint_committee_on_cancer_tumor_stage_code" nillable="true">
			435	<xs:complexType>
			436	<xs:simpleContent>
			437	<xs:restriction base="utility:clinical_res_attributes">
			438	<xs:enumeration value="" />
			439	<xs:enumeration value="T0" />
			440	<xs:enumeration value="T1" />
			441	<xs:enumeration value="T1a" />
			442	<xs:enumeration value="T1b" />
			443	<xs:enumeration value="T1c" />
			444	<xs:enumeration value="T1mi" />
			445	<xs:enumeration value="T2" />
			446	<xs:enumeration value="T2a" />
			447	<xs:enumeration value="T2b" />
			448	<xs:enumeration value="T2c" />
			449	<xs:enumeration value="T3" />
			450	<xs:enumeration value="T3a" />
			451	<xs:enumeration value="T3b" />
			452	<xs:enumeration value="T3c" />
			453	<xs:enumeration value="T4" />
			454	<xs:enumeration value="T4a" />
			455	<xs:enumeration value="T4b" />
			456	<xs:enumeration value="T4c" />
			457	<xs:enumeration value="T4d" />
			458	<xs:enumeration value="Ta" />
			459	<xs:enumeration value="Tis" />
			460	<xs:enumeration value="Tis (DCIS)" />
			461	<xs:enumeration value="Tis (LCIS)" />
			462	<xs:enumeration value="Tis (Paget's)" />
			463	<xs:enumeration value="TX" />
			464	<xs:attribute name="cde" type="xs:string" default="3045435" />
			465	<xs:attribute name="xsd_ver" type="xs:string" default="2.4" />
			466	<xs:attribute name="tier" type="xs:string" default="1" />
			467	</xs:restriction>
			468	</xs:simpleContent>
			469	</xs:complexType>
			470	</xs:element>
		-+	472	<xs:element name="neoplasm_disease_lymph_node_stage_american_joint_committee_on_cancer_code" nillable="true">
			473	<xs:complexType>
			474	<xs:simpleContent>
			475	<xs:restriction base="utility:clinical_res_attributes">
			476	<xs:enumeration value="" />
			477	<xs:enumeration value="N0" />
			478	<xs:enumeration value="N0 (i+)" />
			479	<xs:enumeration value="N0 (i-)" />
			480	<xs:enumeration value="N0 (mol+)" />
			481	<xs:enumeration value="N0 (mol-)" />
			482	<xs:enumeration value="N1" />
			483	<xs:enumeration value="N1a" />
			484	<xs:enumeration value="N1b" />
			485	<xs:enumeration value="N1bI" />
			486	<xs:enumeration value="N1bII" />
			487	<xs:enumeration value="N1bIII" />
			488	<xs:enumeration value="N1bIV" />
			489	<xs:enumeration value="N1c" />
			490	<xs:enumeration value="N1mi" />
			491	<xs:enumeration value="N2" />
			492	<xs:enumeration value="N2a" />
			493	<xs:enumeration value="N2b" />
			494	<xs:enumeration value="N3" />
			495	<xs:enumeration value="N3a" />
			496	<xs:enumeration value="N3b" />
			497	<xs:enumeration value="N3c" />
			498	<xs:enumeration value="N4" />
			499	<xs:enumeration value="NX" />
			500	<xs:attribute name="cde" type="xs:string" default="3203106" />
			501	<xs:attribute name="xsd_ver" type="xs:string" default="2.4" />
			502	<xs:attribute name="tier" type="xs:string" default="1" />
			503	</xs:restriction>
			504	</xs:simpleContent>
			505	</xs:complexType>
			506	</xs:element>
		-+	508	<xs:element name="american_joint_committee_on_cancer_metastasis_stage_code" nillable="true">
			509	<xs:complexType>
			510	<xs:simpleContent>
			511	<xs:restriction base="utility:clinical_res_attributes">
			512	<xs:enumeration value="" />
			513	<xs:enumeration value="cM0 (i+)" />
			514	<xs:enumeration value="M0" />
			515	<xs:enumeration value="M1" />
			516	<xs:enumeration value="M1a" />
			517	<xs:enumeration value="M1b" />
			518	<xs:enumeration value="M1c" />
			519	<xs:enumeration value="MX" />
			520	<xs:attribute name="cde" type="xs:string" default="3045439" />
			521	<xs:attribute name="xsd_ver" type="xs:string" default="2.4" />
			522	<xs:attribute name="tier" type="xs:string" default="1" />
			523	</xs:restriction>
			524	</xs:simpleContent>
			525	</xs:complexType>
			526	</xs:element>
		-+	528	<xs:element name="neoplasm_disease_stage_american_joint_committee_on_cancer_code" nillable="true">
			529	<xs:complexType>
			530	<xs:simpleContent>
			531	<xs:restriction base="utility:clinical_res_attributes">
			532	<xs:enumeration value="" />
			533	<xs:enumeration value="Stage 0" />
			534	<xs:enumeration value="Stage I" />
			535	<xs:enumeration value="Stage IA" />
			536	<xs:enumeration value="Stage IA1" />
			537	<xs:enumeration value="Stage IA2" />
			538	<xs:enumeration value="Stage IB" />
			539	<xs:enumeration value="Stage IB Cervix" />
			540	<xs:enumeration value="Stage IB1" />
			541	<xs:enumeration value="Stage IB2" />
			542	<xs:enumeration value="Stage II" />
			543	<xs:enumeration value="Stage II Cervix" />
			544	<xs:enumeration value="Stage IIA" />
			545	<xs:enumeration value="Stage IIA Cervix" />
			546	<xs:enumeration value="Stage IIB" />
			547	<xs:enumeration value="Stage IIC" />
			548	<xs:enumeration value="Stage III" />
			549	<xs:enumeration value="Stage IIIA" />
			550	<xs:enumeration value="Stage IIIB" />
			551	<xs:enumeration value="Stage IIIC" />
			552	<xs:enumeration value="Stage IV" />
			553	<xs:enumeration value="Stage IVA" />
			554	<xs:enumeration value="Stage IVB" />
			555	<xs:enumeration value="Stage IVC" />
			556	<xs:enumeration value="Stage Tis" />
			557	<xs:enumeration value="Stage X" />
			558	<xs:attribute name="cde" type="xs:string" default="3203222" />
			559	<xs:attribute name="xsd_ver" type="xs:string" default="2.4" />
			560	<xs:attribute name="tier" type="xs:string" default="1" />
			561	</xs:restriction>
			562	</xs:simpleContent>
			563	</xs:complexType>
			564	</xs:element>
487	<xs:extension base="utility:number_or_null">	<>	602	<xs:extension base="xs:decimal">
492	<xs:attribute name="units" type="xs:string" fixed="ng/ml"/>	+-
501	<xs:extension base="utility:number_or_null">	<>	615	<xs:extension base="xs:decimal">
506	<xs:attribute name="units" type="xs:string" fixed="ng/ml"/>	+-
515	<xs:extension base="utility:number_or_null">	<>	628	<xs:extension base="xs:decimal">
520	<xs:attribute name="units" type="xs:string" fixed="ng/ml"/>	+-
526	<xs:element name="lab_procedure_platelet_result_specified_value" nillable="true">	<>	638	<xs:element name="laboratory_procedure_platelet_result_specified_value" nillable="true">
529	<xs:extension base="utility:number_or_null">	<>	641	<xs:extension base="xs:decimal">
534	<xs:attribute name="units" type="xs:string" fixed="1000/uL"/>	+-
543	<xs:extension base="utility:number_or_null">	<>	654	<xs:extension base="xs:decimal">
556	<xs:extension base="utility:number_or_null">	<>	667	<xs:extension base="xs:decimal">
569	<xs:extension base="utility:number_or_null">	<>	680	<xs:extension base="xs:decimal">
574	<xs:attribute name="units" type="xs:string" fixed="seconds"/>	+-
583	<xs:extension base="utility:number_or_null">	<>	693	<xs:extension base="xs:decimal">
588	<xs:attribute name="units" type="xs:string" fixed="seconds"/>	+-
597	<xs:extension base="utility:number_or_null">	<>	706	<xs:extension base="xs:decimal">
602	<xs:attribute name="units" type="xs:string" fixed="seconds"/>	+-
611	<xs:extension base="utility:number_or_null">	<>	719	<xs:extension base="xs:decimal">
616	<xs:attribute name="units" type="xs:string" fixed="mg/dL"/>	+-
625	<xs:extension base="utility:number_or_null">	<>	732	<xs:extension base="xs:decimal">
630	<xs:attribute name="units" type="xs:string" fixed="mg/dL"/>	+-
639	<xs:extension base="utility:number_or_null">	<>	745	<xs:extension base="xs:decimal">
644	<xs:attribute name="units" type="xs:string" fixed="mg/dL"/>	+-
653	<xs:extension base="utility:number_or_null">	<>	758	<xs:extension base="xs:decimal">
658	<xs:attribute name="units" type="xs:string" fixed="mg/dL"/>	+-
667	<xs:extension base="utility:number_or_null">	<>	771	<xs:extension base="xs:decimal">
672	<xs:attribute name="units" type="xs:string" fixed="mg/dL"/>	+-
681	<xs:extension base="utility:number_or_null">	<>	784	<xs:extension base="xs:decimal">
686	<xs:attribute name="units" type="xs:string" fixed="mg/dL"/>	+-
695	<xs:extension base="utility:number_or_null">	<>	797	<xs:extension base="xs:decimal">
700	<xs:attribute name="units" type="xs:string" fixed="mg/dL"/>	+-
709	<xs:extension base="utility:number_or_null">	<>	810	<xs:extension base="xs:decimal">
714	<xs:attribute name="units" type="xs:string" fixed="mg/dL"/>	+-
723	<xs:extension base="utility:number_or_null">	<>	823	<xs:extension base="xs:decimal">
728	<xs:attribute name="units" type="xs:string" fixed="mg/dL"/>	+-
		-+	869	<xs:element name="performance_status_assessment_eastern_cooperative_oncology_group_scale" nillable="true">
			870	<xs:complexType mixed="true">
			871	<xs:simpleContent>
			872	<xs:restriction base="utility:clinical_res_attributes">
			873	<xs:enumeration value="" />
			874	<xs:enumeration value="0" />
			875	<xs:enumeration value="1" />
			876	<xs:enumeration value="2" />
			877	<xs:enumeration value="3" />
			878	<xs:enumeration value="4" />
			879	<xs:enumeration value="5" />
			880	<xs:attribute name="cde" type="xs:string" default="88" />
			881	<xs:attribute name="xsd_ver" type="xs:string" default="2.4" />
			882	<xs:attribute name="tier" type="xs:string" default="2" />
			883	</xs:restriction>
			884	</xs:simpleContent>
			885	</xs:complexType>
			886	</xs:element>

   
File: TCGA_BCR.LIHC_Clinical_FollowUp_v1.0.xsd  

1	<?xml version="1.0" encoding="utf-8" ?>	+-
4	<xs:schema elementFormDefault="qualified" version="2.5.0"	+-
5	xmlns:xs="http://www.w3.org/2001/XMLSchema"
6	xmlns:shared="http://tcga.nci/bcr/xml/clinical/shared/2.5"
7	xmlns:lihc_shared="http://tcga.nci/bcr/xml/clinical/lihc/shared/2.5"
8	xmlns="http://tcga.nci/bcr/xml/clinical/lihc/followup/2.5/1.0"
9	targetNamespace="http://tcga.nci/bcr/xml/clinical/lihc/followup/2.5/1.0"
10	xmlns:jaxb="http://java.sun.com/xml/ns/jaxb" jaxb:version="1.0" >
12	<xs:annotation>	+-
13	<xs:appinfo>
14	<jaxb:globalBindings generateIsSetMethod="true" />
16	<jaxb:schemaBindings>	+-
17	<jaxb:package name="nci.tcga.bcr.xml.jaxb.clinical.lihc" />
18	</jaxb:schemaBindings>
19	</xs:appinfo>
20	</xs:annotation>
22	<xs:annotation>	+-
23	<xs:documentation xml:lang="en">Schema to define the elements of the TCGA Clinical Data Follow-up Form within the LIHC study.</xs:documentation>
24	</xs:annotation>
26	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/shared/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/shared/2.5/TCGA_BCR.Shared_Clinical_Elements.xsd" />	+-
27	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/lihc/shared/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/lihc/shared/2.5/TCGA_BCR.LIHC_Clinical_Shared_Datatypes.xsd" />
29	<xs:element name="follow_up_v1.0">	+-
30	<xs:complexType>
31	<xs:sequence>
32	<xs:element ref="shared:bcr_patient_barcode" />
33	<xs:element ref="shared:bcr_patient_uuid" />
35	<xs:choice>	+-
36	<xs:sequence>
37	<xs:element ref="shared:day_of_form_completion" />
38	<xs:element ref="shared:month_of_form_completion" />
39	<xs:element ref="shared:year_of_form_completion" />
40	</xs:sequence>
42	<xs:element ref="shared:days_to_form_completion" />	+-
43	</xs:choice>
45	<xs:element ref="shared:radiation_therapy" />	+-
46	<xs:element ref="shared:targeted_molecular_therapy" />
47	<xs:element ref="lihc_shared:adjuvant_postoperative_embolization_or_ablation_therapeutic_procedure_performed_indicator" />
48	<xs:element ref="shared:vital_status" />
49	<xs:element ref="shared:person_neoplasm_cancer_status" />
51	<xs:choice>	+-
52	<xs:sequence>
53	<xs:element ref="shared:day_of_last_followup" />
54	<xs:element ref="shared:month_of_last_followup" />
55	<xs:element ref="shared:year_of_last_followup" />
56	</xs:sequence>
58	<xs:element ref="shared:days_to_last_followup" />	+-
59	</xs:choice>
61	<xs:choice>	+-
62	<xs:sequence>
63	<xs:element ref="shared:day_of_last_known_alive" />
64	<xs:element ref="shared:month_of_last_known_alive" />
65	<xs:element ref="shared:year_of_last_known_alive" />
66	</xs:sequence>
68	<xs:element ref="shared:days_to_last_known_alive" />	+-
69	</xs:choice>
71	<xs:choice>	+-
72	<xs:sequence>
73	<xs:element ref="shared:day_of_death" />
74	<xs:element ref="shared:month_of_death" />
75	<xs:element ref="shared:year_of_death" />
76	</xs:sequence>
78	<xs:element ref="shared:days_to_death" />	+-
79	</xs:choice>
81	<xs:element ref="shared:new_tumor_event_after_initial_treatment" />	+-
82	<xs:element ref="shared:new_neoplasm_event_type" />
84	<xs:choice>	+-
85	<xs:sequence>
86	<xs:element ref="shared:day_of_new_tumor_event_after_initial_treatment" />
87	<xs:element ref="shared:month_of_new_tumor_event_after_initial_treatment" />
88	<xs:element ref="shared:year_of_new_tumor_event_after_initial_treatment" />
89	</xs:sequence>
91	<xs:element ref="shared:days_to_new_tumor_event_after_initial_treatment" />	+-
92	</xs:choice>
94	<xs:element ref="lihc_shared:extrahepatic_recurrent_disease_anatomic_site_name" />	+-
95	<xs:element ref="lihc_shared:extrahepatic_recurrent_disease_location_text" />
96	<xs:element ref="shared:additional_surgery_locoregional_procedure" />
98	<xs:choice>	+-
99	<xs:sequence>
100	<xs:element ref="shared:day_of_additional_surgery_metastatic_procedure" />
101	<xs:element ref="shared:month_of_additional_surgery_metastatic_procedure" />
102	<xs:element ref="shared:year_of_additional_surgery_metastatic_procedure" />
103	</xs:sequence>
105	<xs:element ref="shared:days_to_additional_surgery_metastatic_procedure" />	+-
106	</xs:choice>
108	<xs:element ref="shared:residual_disease_post_new_tumor_event_margin_status" />	+-
109	<xs:element ref="lihc_shared:liver_graft_together_new_neoplasm_performed_indicator" />
111	<xs:choice>	+-
112	<xs:sequence>
113	<xs:element ref="lihc_shared:day_of_liver_graft_together_new_neoplasm_performed" />
114	<xs:element ref="lihc_shared:month_of_liver_graft_together_new_neoplasm_performed" />
115	<xs:element ref="lihc_shared:year_of_liver_graft_together_new_neoplasm_performed" />
116	</xs:sequence>
118	<xs:element ref="lihc_shared:days_to_liver_graft_together_new_neoplasm_performed" />	+-
119	</xs:choice>
121	<xs:element ref="shared:additional_radiation_therapy" />	+-
122	<xs:element ref="shared:additional_pharmaceutical_therapy" />
123	<xs:element ref="lihc_shared:additional_embolization_or_ablation_therapeutic_procedure_post_recurrent_disease_performed_indicator" />
124	</xs:sequence>
126	<xs:attribute name="version" type="xs:string" default="1.0" use="optional"/>	+-
127	</xs:complexType>
128	</xs:element>
129	</xs:schema>

   
File: TCGA_BCR.LIHC_Clinical_FollowUp_v2.0.xsd  

1	<?xml version="1.0" encoding="utf-8" ?>	+-
4	<xs:schema elementFormDefault="qualified" version="2.5.0"	+-
5	xmlns:xs="http://www.w3.org/2001/XMLSchema"
6	xmlns:shared="http://tcga.nci/bcr/xml/clinical/shared/2.5"
7	xmlns:lihc_shared="http://tcga.nci/bcr/xml/clinical/lihc/shared/2.5"
8	xmlns="http://tcga.nci/bcr/xml/clinical/lihc/followup/2.5/2.0"
9	targetNamespace="http://tcga.nci/bcr/xml/clinical/lihc/followup/2.5/2.0"
10	xmlns:jaxb="http://java.sun.com/xml/ns/jaxb" jaxb:version="1.0" >
12	<xs:annotation>	+-
13	<xs:appinfo>
14	<jaxb:globalBindings generateIsSetMethod="true" />
16	<jaxb:schemaBindings>	+-
17	<jaxb:package name="nci.tcga.bcr.xml.jaxb.clinical.lihc" />
18	</jaxb:schemaBindings>
19	</xs:appinfo>
20	</xs:annotation>
22	<xs:annotation>	+-
23	<xs:documentation xml:lang="en">Schema to define the elements of the TCGA Clinical Data Follow-up Form within the LIHC study.</xs:documentation>
24	</xs:annotation>
26	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/shared/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/shared/2.5/TCGA_BCR.Shared_Clinical_Elements.xsd" />	+-
27	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/lihc/shared/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/lihc/shared/2.5/TCGA_BCR.LIHC_Clinical_Shared_Datatypes.xsd" />
29	<xs:element name="follow_up_v2.0">	+-
30	<xs:complexType>
31	<xs:sequence>
32	<xs:element ref="shared:bcr_patient_barcode" />
33	<xs:element ref="shared:bcr_patient_uuid" />
35	<xs:choice>	+-
36	<xs:sequence>
37	<xs:element ref="shared:day_of_form_completion" />
38	<xs:element ref="shared:month_of_form_completion" />
39	<xs:element ref="shared:year_of_form_completion" />
40	</xs:sequence>
42	<xs:element ref="shared:days_to_form_completion" />	+-
43	</xs:choice>
45	<xs:element ref="shared:followup_case_report_form_submission_reason" />	+-
46	<xs:element ref="shared:radiation_therapy" />
47	<xs:element ref="shared:targeted_molecular_therapy" />
48	<xs:element ref="lihc_shared:adjuvant_postoperative_embolization_or_ablation_therapeutic_procedure_performed_indicator" />
49	<xs:element ref="shared:vital_status" />
51	<xs:choice>	+-
52	<xs:sequence>
53	<xs:element ref="shared:day_of_last_followup" />
54	<xs:element ref="shared:month_of_last_followup" />
55	<xs:element ref="shared:year_of_last_followup" />
56	</xs:sequence>
58	<xs:element ref="shared:days_to_last_followup" />	+-
59	</xs:choice>
61	<xs:choice>	+-
62	<xs:sequence>
63	<xs:element ref="shared:day_of_death" />
64	<xs:element ref="shared:month_of_death" />
65	<xs:element ref="shared:year_of_death" />
66	</xs:sequence>
68	<xs:element ref="shared:days_to_death" />	+-
69	</xs:choice>
71	<xs:element ref="shared:person_neoplasm_cancer_status" />	+-
72	<xs:element ref="shared:new_tumor_event_after_initial_treatment" />
74	<xs:choice>	+-
75	<xs:sequence>
76	<xs:element ref="shared:day_of_new_tumor_event_after_initial_treatment" />
77	<xs:element ref="shared:month_of_new_tumor_event_after_initial_treatment" />
78	<xs:element ref="shared:year_of_new_tumor_event_after_initial_treatment" />
79	</xs:sequence>
81	<xs:element ref="shared:days_to_new_tumor_event_after_initial_treatment" />	+-
82	</xs:choice>
84	<xs:element ref="shared:new_neoplasm_event_type" />	+-
85	<xs:element ref="lihc_shared:new_neoplasm_event_occurrence_anatomic_site" />
86	<xs:element ref="lihc_shared:new_neoplasm_occurrence_anatomic_site_text" />
87	<xs:element ref="shared:additional_surgery_locoregional_procedure" />
89	<xs:choice>	+-
90	<xs:sequence>
91	<xs:element ref="shared:day_of_additional_surgery_metastatic_procedure" />
92	<xs:element ref="shared:month_of_additional_surgery_metastatic_procedure" />
93	<xs:element ref="shared:year_of_additional_surgery_metastatic_procedure" />
94	</xs:sequence>
96	<xs:element ref="shared:days_to_additional_surgery_metastatic_procedure" />	+-
97	</xs:choice>
99	<xs:element ref="shared:residual_disease_post_new_tumor_event_margin_status" />	+-
100	<xs:element ref="lihc_shared:liver_graft_together_new_neoplasm_performed_indicator" />
102	<xs:choice>	+-
103	<xs:sequence>
104	<xs:element ref="lihc_shared:day_of_liver_graft_together_new_neoplasm_performed" />
105	<xs:element ref="lihc_shared:month_of_liver_graft_together_new_neoplasm_performed" />
106	<xs:element ref="lihc_shared:year_of_liver_graft_together_new_neoplasm_performed" />
107	</xs:sequence>
109	<xs:element ref="lihc_shared:days_to_liver_graft_together_new_neoplasm_performed" />	+-
110	</xs:choice>
112	<xs:element ref="shared:additional_radiation_therapy" />	+-
113	<xs:element ref="shared:additional_pharmaceutical_therapy" />
114	<xs:element ref="lihc_shared:additional_embolization_or_ablation_therapeutic_procedure_post_recurrent_disease_performed_indicator" />
115	</xs:sequence>
117	<xs:attribute name="version" type="xs:string" default="2.0" use="optional"/>	+-
118	</xs:complexType>
119	</xs:element>
120	</xs:schema>

   
File: TCGA_BCR.LIHC_Clinical_Shared_Datatypes.xsd  

1	<?xml version="1.0" encoding="utf-8" ?>	+-
4	<xs:schema elementFormDefault="qualified" version="2.5.0"	+-
5	xmlns:xs="http://www.w3.org/2001/XMLSchema"
6	xmlns:utility="http://tcga.nci/bcr/xml/utility/2.5"
7	xmlns="http://tcga.nci/bcr/xml/clinical/lihc/shared/2.5"
8	targetNamespace="http://tcga.nci/bcr/xml/clinical/lihc/shared/2.5">
10	<xs:import namespace="http://tcga.nci/bcr/xml/utility/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/utility/2.5/TCGA_BCR.Utility.xsd" />	+-
12	<xs:element name="adjuvant_postoperative_embolization_or_ablation_therapeutic_procedure_performed_indicator" nillable="true">	+-
13	<xs:complexType mixed="true">
14	<xs:simpleContent>
15	<xs:restriction base="utility:clinical_res_attributes">
16	<xs:enumeration value="" />
17	<xs:enumeration value="No" />
18	<xs:enumeration value="Unknown" />
19	<xs:enumeration value="Yes" />
20	<xs:attribute name="cde" type="xs:string" default="3172120" />
21	<xs:attribute name="xsd_ver" type="xs:string" default="2.5" />
22	<xs:attribute name="tier" type="xs:string" default="2" />
23	</xs:restriction>
24	</xs:simpleContent>
25	</xs:complexType>
26	</xs:element>
28	<xs:element name="extrahepatic_recurrent_disease_anatomic_site_name" nillable="true">	+-
29	<xs:complexType mixed="true">
30	<xs:simpleContent>
31	<xs:restriction base="utility:clinical_res_attributes">
32	<xs:enumeration value="" />
33	<xs:enumeration value="Bone" />
34	<xs:enumeration value="Lymph nodes" />
35	<xs:enumeration value="Lung" />
36	<xs:enumeration value="Other" />
37	<xs:attribute name="cde" type="xs:string" default="3173028" />
38	<xs:attribute name="xsd_ver" type="xs:string" default="2.5" />
39	<xs:attribute name="tier" type="xs:string" default="2" />
40	</xs:restriction>
41	</xs:simpleContent>
42	</xs:complexType>
43	</xs:element>
45	<xs:element name="extrahepatic_recurrent_disease_location_text" nillable="true">	+-
46	<xs:complexType>
47	<xs:simpleContent>
48	<xs:extension base="xs:string">
49	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
50	<xs:attribute name="cde" type="xs:string" default="3173045" />
51	<xs:attribute name="xsd_ver" type="xs:string" default="2.5" />
52	<xs:attribute name="tier" type="xs:string" default="2" />
53	</xs:extension>
54	</xs:simpleContent>
55	</xs:complexType>
56	</xs:element>
58	<xs:element name="liver_graft_together_new_neoplasm_performed_indicator" nillable="true">	+-
59	<xs:complexType mixed="true">
60	<xs:simpleContent>
61	<xs:restriction base="utility:clinical_res_attributes">
62	<xs:enumeration value="" />
63	<xs:enumeration value="No" />
64	<xs:enumeration value="Unknown" />
65	<xs:enumeration value="Yes" />
66	<xs:attribute name="cde" type="xs:string" default="3168060" />
67	<xs:attribute name="xsd_ver" type="xs:string" default="2.5" />
68	<xs:attribute name="tier" type="xs:string" default="2" />
69	</xs:restriction>
70	</xs:simpleContent>
71	</xs:complexType>
72	</xs:element>
74	<xs:element name="day_of_liver_graft_together_new_neoplasm_performed" nillable="true">	+-
75	<xs:complexType mixed="true">
76	<xs:simpleContent>
77	<xs:extension base="utility:generic_day">
78	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
79	<xs:attribute name="cde" type="xs:string" default="3168021" />
80	<xs:attribute name="xsd_ver" type="xs:string" default="2.5" />
81	<xs:attribute name="tier" type="xs:string" default="1" />
82	</xs:extension>
83	</xs:simpleContent>
84	</xs:complexType>
85	</xs:element>
87	<xs:element name="month_of_liver_graft_together_new_neoplasm_performed" nillable="true">	+-
88	<xs:complexType mixed="true">
89	<xs:simpleContent>
90	<xs:extension base="utility:generic_month">
91	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
92	<xs:attribute name="cde" type="xs:string" default="3168022" />
93	<xs:attribute name="xsd_ver" type="xs:string" default="2.5" />
94	<xs:attribute name="tier" type="xs:string" default="1" />
95	</xs:extension>
96	</xs:simpleContent>
97	</xs:complexType>
98	</xs:element>
100	<xs:element name="year_of_liver_graft_together_new_neoplasm_performed" nillable="true">	+-
101	<xs:complexType mixed="true">
102	<xs:simpleContent>
103	<xs:extension base="utility:generic_year">
104	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
105	<xs:attribute name="cde" type="xs:string" default="3168037" />
106	<xs:attribute name="xsd_ver" type="xs:string" default="2.5" />
107	<xs:attribute name="tier" type="xs:string" default="1" />
108	</xs:extension>
109	</xs:simpleContent>
110	</xs:complexType>
111	</xs:element>
113	<xs:element name="days_to_liver_graft_together_new_neoplasm_performed">	+-
114	<xs:complexType mixed="true">
115	<xs:simpleContent>
116	<xs:restriction base="utility:clinical_res_attributes">
117	<xs:attribute name="cde" type="xs:string" default="" />
118	<xs:attribute name="xsd_ver" type="xs:string" default="2.5" />
119	<xs:attribute name="tier" type="xs:string" default="1" />
120	</xs:restriction>
121	</xs:simpleContent>
122	</xs:complexType>
123	</xs:element>
125	<xs:element name="new_neoplasm_event_occurrence_anatomic_site" nillable="true">	+-
126	<xs:complexType mixed="true">
127	<xs:simpleContent>
128	<xs:restriction base="utility:clinical_res_attributes">
129	<xs:enumeration value="" />
130	<xs:enumeration value="Anus" />
131	<xs:enumeration value="Bladder" />
132	<xs:enumeration value="Bone" />
133	<xs:enumeration value="Brain" />
134	<xs:enumeration value="Cervical Lymph Node" />
135	<xs:enumeration value="Cervix" />
136	<xs:enumeration value="Distant Metastasis " />
137	<xs:enumeration value="Head &amp; Neck" />
138	<xs:enumeration value="Hypopharynx" />
139	<xs:enumeration value="Larynx" />
140	<xs:enumeration value="Liver" />
141	<xs:enumeration value="Lung" />
142	<xs:enumeration value="Lymph Node Only" />
143	<xs:enumeration value="Non-regional / Distant Lymph Nodes" />
144	<xs:enumeration value="Not Applicable" />
145	<xs:enumeration value="Oral Cavity" />
146	<xs:enumeration value="Oropharynx" />
147	<xs:enumeration value="Other, specify" />
148	<xs:enumeration value="Peritoneal Surfaces" />
149	<xs:enumeration value="Renal Pelvis" />
150	<xs:enumeration value="Ureter" />
151	<xs:enumeration value="Urethra" />
152	<xs:enumeration value="Vulva" />
153	<xs:attribute name="cde" type="xs:string" default="3108271" />
154	<xs:attribute name="xsd_ver" type="xs:string" default="2.5" />
155	<xs:attribute name="tier" type="xs:string" default="2" />
156	</xs:restriction>
157	</xs:simpleContent>
158	</xs:complexType>
159	</xs:element>
161	<xs:element name="new_neoplasm_occurrence_anatomic_site_text" nillable="true">	+-
162	<xs:complexType>
163	<xs:simpleContent>
164	<xs:extension base="xs:string">
165	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
166	<xs:attribute name="cde" type="xs:string" default="3128033" />
167	<xs:attribute name="xsd_ver" type="xs:string" default="2.5" />
168	<xs:attribute name="tier" type="xs:string" default="2" />
169	</xs:extension>
170	</xs:simpleContent>
171	</xs:complexType>
172	</xs:element>
174	<xs:element name="additional_embolization_or_ablation_therapeutic_procedure_post_recurrent_disease_performed_indicator" nillable="true">	+-
175	<xs:complexType mixed="true">
176	<xs:simpleContent>
177	<xs:restriction base="utility:clinical_res_attributes">
178	<xs:enumeration value="" />
179	<xs:enumeration value="No" />
180	<xs:enumeration value="Unknown" />
181	<xs:enumeration value="Yes" />
182	<xs:attribute name="cde" type="xs:string" default="3173961" />
183	<xs:attribute name="xsd_ver" type="xs:string" default="2.5" />
184	<xs:attribute name="tier" type="xs:string" default="2" />
185	</xs:restriction>
186	</xs:simpleContent>
187	</xs:complexType>
188	</xs:element>
190	</xs:schema>	+-

   
File: TCGA_BCR.LUAD_Clinical.xsd  

4	<xs:schema elementFormDefault="qualified" version="2.5.0"	<>	4	<xs:schema elementFormDefault="qualified" version="2.4.4"
6	xmlns:utility="http://tcga.nci/bcr/xml/utility/2.5"	<>	6	xmlns:utility="http://tcga.nci/bcr/xml/utility/2.4"
7	xmlns:admin="http://tcga.nci/bcr/xml/administration/2.5"		7	xmlns:admin="http://tcga.nci/bcr/xml/administration/2.4"
8	xmlns:shared="http://tcga.nci/bcr/xml/clinical/shared/2.5"		8	xmlns:shared="http://tcga.nci/bcr/xml/clinical/shared/2.4"
9	xmlns:lusc_luad_shared="http://tcga.nci/bcr/xml/clinical/shared/lusc_luad/2.5"
10	xmlns:rad="http://tcga.nci/bcr/xml/clinical/radiation/2.5"		9	xmlns:rad="http://tcga.nci/bcr/xml/clinical/radiation/2.4"
11	xmlns:rx="http://tcga.nci/bcr/xml/clinical/pharmaceutical/2.5"		10	xmlns:rx="http://tcga.nci/bcr/xml/clinical/pharmaceutical/2.4"
12	xmlns:cqcf="http://tcga.nci/bcr/xml/clinical/cqcf/2.5"
13	xmlns:follow_up_v1.0="http://tcga.nci/bcr/xml/clinical/luad/followup/2.5/1.0"
14	xmlns="http://tcga.nci/bcr/xml/clinical/luad/2.5"		11	xmlns="http://tcga.nci/bcr/xml/clinical/luad/2.4"
15	targetNamespace="http://tcga.nci/bcr/xml/clinical/luad/2.5"		12	targetNamespace="http://tcga.nci/bcr/xml/clinical/luad/2.4"
33	<xs:import namespace="http://tcga.nci/bcr/xml/utility/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/utility/2.5/TCGA_BCR.Utility.xsd" />	<>	28	<xs:import namespace="http://tcga.nci/bcr/xml/utility/2.4" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/utility/2.4/TCGA_BCR.Utility.xsd" />
34	<xs:import namespace="http://tcga.nci/bcr/xml/administration/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/administration/2.5/TCGA_BCR.Administration.xsd" />		29	<xs:import namespace="http://tcga.nci/bcr/xml/administration/2.4" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/administration/2.4/TCGA_BCR.Administration.xsd" />
35	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/shared/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/shared/2.5/TCGA_BCR.Shared_Clinical_Elements.xsd" />		30	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/shared/2.4" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/shared/2.4/TCGA_BCR.Shared_Clinical_Elements.xsd" />
36	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/radiation/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/radiation/2.5/TCGA_BCR.Radiation.xsd" />		31	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/radiation/2.4" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/radiation/2.4/TCGA_BCR.Radiation.xsd" />
37	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/pharmaceutical/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/pharmaceutical/2.5/TCGA_BCR.Pharmaceutical.xsd" />		32	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/pharmaceutical/2.4" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/pharmaceutical/2.4/TCGA_BCR.Pharmaceutical.xsd" />
38	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/cqcf/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/cqcf/2.5/TCGA_BCR.CQCF.xsd" />
39	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/luad/followup/2.5/1.0" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/luad/followup/2.5/TCGA_BCR.LUAD_Clinical_FollowUp_v1.0.xsd" />
40	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/shared/lusc_luad/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/shared/2.5/TCGA_BCR.Shared_Clinical_LUSC_LUAD_Elements.xsd" />
49	<xs:attribute name="schemaVersion" type="xs:decimal" use="required" fixed="2.5"/>	<>	41	<xs:attribute name="schemaVersion" type="xs:decimal" use="required" fixed="2.4"/>
57	<xs:element ref="lusc_luad_shared:histological_type" />	<>	49	<xs:element ref="histological_type" />
142	<xs:element ref="lusc_luad_shared:tumor_stage" />	<>	135	<xs:element ref="tumor_stage" />
143	<xs:element ref="lusc_luad_shared:primary_tumor_pathologic_spread" />		136	<xs:element ref="primary_tumor_pathologic_spread" />
144	<xs:element ref="lusc_luad_shared:lymphnode_pathologic_spread" />		137	<xs:element ref="lymphnode_pathologic_spread" />
145	<xs:element ref="lusc_luad_shared:distant_metastasis_pathologic_spread" />		138	<xs:element ref="distant_metastasis_pathologic_spread" />
146	<xs:element ref="shared:karnofsky_performance_score" />		139	<xs:element ref="karnofsky_performance_score" />
147	<xs:element ref="shared:eastern_cancer_oncology_group" />		140	<xs:element ref="eastern_cancer_oncology_group" />
148	<xs:element ref="lusc_luad_shared:tobacco_smoking_history_indicator" />		141	<xs:element ref="tobacco_smoking_history_indicator" />
149	<xs:element ref="lusc_luad_shared:year_of_tobacco_smoking_onset" />		142	<xs:element ref="year_of_tobacco_smoking_onset" />
150	<xs:element ref="shared:stopped_smoking_year" />		143	<xs:element ref="year_of_tobacco_smoking_cessation" />
151	<xs:element ref="shared:number_pack_years_smoked" />		144	<xs:element ref="number_pack_years_smoked" />
152	<xs:element ref="shared:anatomic_organ_subdivision" />		145	<xs:element ref="anatomic_organ_subdivision" />
153	<xs:element ref="lusc_luad_shared:diagnosis" />		146	<xs:element ref="diagnosis" />
154	<xs:element ref="lusc_luad_shared:location_in_lung_parenchyma" />		147	<xs:element ref="location_in_lung_parenchyma" />
155	<xs:element ref="shared:residual_tumor" />		148	<xs:element ref="residual_tumor" />
156	<xs:element ref="lusc_luad_shared:kras_mutation_found" />		149	<xs:element ref="kras_mutation_found" />
157	<xs:element ref="lusc_luad_shared:kras_gene_analysis_performed" />		150	<xs:element ref="kras_gene_analysis_performed" />
158	<xs:element ref="lusc_luad_shared:kras_mutation_result" />		151	<xs:element ref="kras_mutation_result" />
159	<xs:element ref="lusc_luad_shared:egfr_mutation_performed" />		152	<xs:element ref="egfr_mutation_performed" />
160	<xs:element ref="lusc_luad_shared:egfr_mutation_result" />		153	<xs:element ref="egfr_mutation_result" />
161	<xs:element ref="lusc_luad_shared:eml4_alk_translocation_performed" />		154	<xs:element ref="eml4_alk_translocation_performed" />
162	<xs:element ref="lusc_luad_shared:eml4_alk_translocation_result" />		155	<xs:element ref="eml4_alk_translocation_result" />
163	<xs:element ref="lusc_luad_shared:eml4_alk_translocation_method" />		156	<xs:element ref="eml4_alk_translocation_method" />
166		<>	159	</xs:sequence>
			160	</xs:complexType>
			161	</xs:element>
167	<xs:element ref="lusc_luad_shared:clinical_cqcf" />	<>	163	<xs:element name="egfr_mutation_result" nillable="true">
168			164	<xs:complexType mixed="true">
			165	<xs:simpleContent>
			166	<xs:restriction base="utility:clinical_res_attributes">
169	<xs:element name="follow_ups">		167	<xs:enumeration value="" />
			168	<xs:enumeration value="G719X" />
			169	<xs:enumeration value="Exon 19 Deletion" />
			170	<xs:enumeration value="Exon 20 Insertion" />
			171	<xs:enumeration value="T790M" />
			172	<xs:enumeration value="L858R" />
			173	<xs:enumeration value="L861Q" />
			174	<xs:enumeration value="Other" />
			175	<xs:attribute name="cde" type="xs:string" default="3147627" />
			176	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			177	<xs:attribute name="tier" type="xs:string" default="2" />
			178	</xs:restriction>
			179	</xs:simpleContent>
			180	</xs:complexType>
			181	</xs:element>
		<>	183	<xs:element name="eml4_alk_translocation_result" nillable="true">
			184	<xs:complexType mixed="true">
170	<xs:annotation>		185	<xs:simpleContent>
171	<xs:documentation>We are using namespaces and version numbers to distinguish one version of followup from another.</xs:documentation>		186	<xs:restriction base="utility:clinical_res_attributes">
			187	<xs:enumeration value="" />
			188	<xs:enumeration value="Variant 1" />
			189	<xs:enumeration value="Variant 2" />
			190	<xs:enumeration value="Variant 3" />
			191	<xs:enumeration value="Variant 4" />
			192	<xs:enumeration value="Variant 5" />
			193	<xs:attribute name="cde" type="xs:string" default="3139445" />
			194	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			195	<xs:attribute name="tier" type="xs:string" default="2" />
			196	</xs:restriction>
			197	</xs:simpleContent>
			198	</xs:complexType>
			199	</xs:element>
		-+	201	<xs:element name="eml4_alk_translocation_method" nillable="true">
			202	<xs:complexType mixed="true">
			203	<xs:simpleContent>
			204	<xs:restriction base="utility:clinical_res_attributes">
			205	<xs:enumeration value="" />
			206	<xs:enumeration value="IHC" />
			207	<xs:enumeration value="FISH" />
			208	<xs:enumeration value="RT-PCR" />
			209	<xs:enumeration value="Other" />
			210	<xs:attribute name="cde" type="xs:string" default="3139449" />
			211	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			212	<xs:attribute name="tier" type="xs:string" default="2" />
			213	</xs:restriction>
			214	</xs:simpleContent>
			215	</xs:complexType>
			216	</xs:element>
		<>	218	<xs:element name="egfr_mutation_performed" nillable="true">
			219	<xs:complexType>
			220	<xs:simpleContent>
			221	<xs:extension base="utility:yes_or_no">
			222	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			223	<xs:attribute name="cde" type="xs:string" default="3139429" />
			224	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			225	<xs:attribute name="tier" type="xs:string" default="1" />
172	</xs:annotation>		226	</xs:extension>
			227	</xs:simpleContent>
			228	</xs:complexType>
			229	</xs:element>
		-+	231	<xs:element name="eml4_alk_translocation_performed" nillable="true">
		<>	233	<xs:simpleContent>
			234	<xs:extension base="utility:yes_or_no">
			235	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			236	<xs:attribute name="cde" type="xs:string" default="3139437" />
			237	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			238	<xs:attribute name="tier" type="xs:string" default="1" />
			239	</xs:extension>
			240	</xs:simpleContent>
			241	</xs:complexType>
174	<xs:sequence>		242	</xs:element>
		-+	244	<xs:element name="histological_type" nillable="true">
			245	<xs:complexType mixed="true">
			246	<xs:simpleContent>
			247	<xs:restriction base="utility:clinical_res_attributes">
			248	<xs:attribute name="cde" type="xs:string" default="3081934" />
			249	<xs:attribute name="xsd_ver" type="xs:string" default="1.9" />
			250	<xs:attribute name="tier" type="xs:string" default="1" />
			251	</xs:restriction>
			252	</xs:simpleContent>
			253	</xs:complexType>
			254	</xs:element>
		-+	256	<xs:element name="diagnosis" nillable="true">
			257	<xs:complexType mixed="true">
			258	<xs:simpleContent>
			259	<xs:restriction base="utility:clinical_res_attributes">
			260	<xs:attribute name="cde" type="xs:string" default="3081932" />
			261	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			262	<xs:attribute name="tier" type="xs:string" default="1" />
			263	</xs:restriction>
			264	</xs:simpleContent>
			265	</xs:complexType>
			266	</xs:element>
		-+	268	<xs:element name="location_in_lung_parenchyma" nillable="true">
			269	<xs:complexType mixed="true">
			270	<xs:simpleContent>
			271	<xs:restriction base="utility:clinical_res_attributes">
			272	<xs:enumeration value="" />
			273	<xs:enumeration value="Peripheral Lung" />
			274	<xs:enumeration value="Central Lung" />
			275	<xs:attribute name="cde" type="xs:string" default="3139453" />
			276	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			277	<xs:attribute name="tier" type="xs:string" default="2" />
			278	</xs:restriction>
			279	</xs:simpleContent>
			280	</xs:complexType>
			281	</xs:element>
		-+	283	<xs:element name="anatomic_organ_subdivision" nillable="true">
			284	<xs:complexType mixed="true">
			285	<xs:simpleContent>
			286	<xs:restriction base="utility:clinical_res_attributes">
			287	<xs:enumeration value="" />
			288	<xs:enumeration value="R-Upper" />
			289	<xs:enumeration value="R-Middle" />
			290	<xs:enumeration value="R-Lower" />
			291	<xs:enumeration value="L-Upper" />
			292	<xs:enumeration value="L-Lower" />
			293	<xs:enumeration value="Bronchial" />
			294	<xs:enumeration value="Mediastinal" />
			295	<xs:attribute name="cde" type="xs:string" default="2008006" />
			296	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			297	<xs:attribute name="tier" type="xs:string" default="2" />
			298	</xs:restriction>
			299	</xs:simpleContent>
			300	</xs:complexType>
			301	</xs:element>
		-+	303	<xs:element name="kras_mutation_result" nillable="true">
			304	<xs:complexType mixed="true">
			305	<xs:simpleContent>
			306	<xs:restriction base="utility:clinical_res_attributes">
			307	<xs:enumeration value="" />
			308	<xs:enumeration value="G12A" />
			309	<xs:enumeration value="G12C" />
			310	<xs:enumeration value="G12D" />
			311	<xs:enumeration value="G12R" />
			312	<xs:enumeration value="G12S" />
			313	<xs:enumeration value="G12V" />
			314	<xs:enumeration value="G13D" />
			315	<xs:enumeration value="Other" />
			316	<xs:attribute name="cde" type="xs:string" default="3147614" />
			317	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			318	<xs:attribute name="tier" type="xs:string" default="2" />
			319	</xs:restriction>
			320	</xs:simpleContent>
			321	</xs:complexType>
			322	</xs:element>
		-+	324	<xs:element name="number_pack_years_smoked" nillable="true">
			325	<xs:complexType mixed="true">
			326	<xs:simpleContent>
			327	<xs:restriction base="utility:clinical_res_attributes">
			328	<xs:attribute name="cde" type="xs:string" default="2955385" />
			329	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			330	<xs:attribute name="tier" type="xs:string" default="1" />
			331	</xs:restriction>
			332	</xs:simpleContent>
			333	</xs:complexType>
			334	</xs:element>
		-+	336	<xs:element name="tobacco_smoking_history_indicator" nillable="true">
			337	<xs:complexType>
			338	<xs:simpleContent>
			339	<xs:restriction base="utility:clinical_res_attributes">
			340	<xs:enumeration value="" />
			341	<xs:enumeration value="Lifelong Non-smoker" />
			342	<xs:enumeration value="Current smoker" />
			343	<xs:enumeration value="Current reformed smoker for &gt; 15 years" />
			344	<xs:enumeration value="Current reformed smoker for &lt; or = 15 years" />
			345	<xs:attribute name="cde" type="xs:string" default="2181650" />
			346	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			347	<xs:attribute name="tier" type="xs:string" default="1" />
			348	</xs:restriction>
			349	</xs:simpleContent>
			350	</xs:complexType>
			351	</xs:element>
175	<xs:element ref="follow_up_v1.0:follow_up_v1.0" minOccurs="0" maxOccurs="unbounded" />	<>	353	<xs:element name="year_of_tobacco_smoking_onset" nillable="true">
			354	<xs:complexType mixed="true">
			355	<xs:simpleContent>
			356	<xs:extension base="utility:generic_year">
			357	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			358	<xs:attribute name="cde" type="xs:string" default="2228604" />
			359	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			360	<xs:attribute name="tier" type="xs:string" default="1" />
			361	</xs:extension>
			362	</xs:simpleContent>
			363	</xs:complexType>
176	</xs:sequence>		364	</xs:element>
		-+	366	<xs:element name="year_of_tobacco_smoking_cessation" nillable="true">
			367	<xs:complexType mixed="true">
			368	<xs:simpleContent>
			369	<xs:extension base="utility:generic_year">
			370	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			371	<xs:attribute name="cde" type="xs:string" default="2228610" />
			372	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			373	<xs:attribute name="tier" type="xs:string" default="1" />
			374	</xs:extension>
			375	</xs:simpleContent>
		<>	379	<xs:element name="kras_mutation_found" nillable="true">
			380	<xs:complexType>
			381	<xs:simpleContent>
			382	<xs:extension base="utility:yes_or_no">
			383	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			384	<xs:attribute name="cde" type="xs:string" default="2932340" />
			385	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			386	<xs:attribute name="tier" type="xs:string" default="1" />
			387	</xs:extension>
			388	</xs:simpleContent>
			389	</xs:complexType>
179	</xs:sequence>		390	</xs:element>
		-+	392	<xs:element name="kras_gene_analysis_performed" nillable="true">
			393	<xs:complexType>
			394	<xs:simpleContent>
			395	<xs:extension base="utility:yes_or_no">
			396	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			397	<xs:attribute name="cde" type="xs:string" default="3123147" />
			398	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			399	<xs:attribute name="tier" type="xs:string" default="1" />
			400	</xs:extension>
			401	</xs:simpleContent>
		-+	405	<xs:element name="residual_tumor" nillable="true">
			406	<xs:complexType>
			407	<xs:simpleContent>
			408	<xs:restriction base="utility:clinical_res_attributes">
			409	<xs:enumeration value="" />
			410	<xs:enumeration value="RX" />
			411	<xs:enumeration value="R0" />
			412	<xs:enumeration value="R1" />
			413	<xs:enumeration value="R2" />
			414	<xs:attribute name="cde" type="xs:string" default="2608702" />
			415	<xs:attribute name="xsd_ver" type="xs:string" default="1.11" />
			416	<xs:attribute name="tier" type="xs:string" default="1" />
			417	</xs:restriction>
			418	</xs:simpleContent>
			419	</xs:complexType>
			420	</xs:element>
		-+	422	<xs:element name="primary_therapy_outcome_success" nillable="true">
			423	<xs:complexType>
			424	<xs:simpleContent>
			425	<xs:restriction base="utility:clinical_res_attributes">
			426	<xs:enumeration value="" />
			427	<xs:enumeration value="PROGRESSIVE DISEASE" />
			428	<xs:enumeration value="STABLE DISEASE" />
			429	<xs:enumeration value="PARTIAL RESPONSE" />
			430	<xs:enumeration value="COMPLETE RESPONSE" />
			431	<xs:attribute name="cde" type="xs:string" default="2786727" />
			432	<xs:attribute name="xsd_ver" type="xs:string" default="1.11" />
			433	<xs:attribute name="tier" type="xs:string" default="2" />
			434	</xs:restriction>
			435	</xs:simpleContent>
			436	</xs:complexType>
			437	</xs:element>
		-+	439	<xs:element name="karnofsky_performance_score">
			440	<xs:complexType>
			441	<xs:simpleContent>
			442	<xs:restriction base="utility:clinical_res_attributes">
			443	<xs:enumeration value="" />
			444	<xs:enumeration value="0" />
			445	<xs:enumeration value="10" />
			446	<xs:enumeration value="20" />
			447	<xs:enumeration value="30" />
			448	<xs:enumeration value="40" />
			449	<xs:enumeration value="50" />
			450	<xs:enumeration value="60" />
			451	<xs:enumeration value="70" />
			452	<xs:enumeration value="80" />
			453	<xs:enumeration value="90" />
			454	<xs:enumeration value="100" />
			455	<xs:attribute name="cde" type="xs:string" default="2003853" />
			456	<xs:attribute name="xsd_ver" type="xs:string" default="1.8" />
			457	<xs:attribute name="tier" type="xs:string" default="2" />
			458	</xs:restriction>
			459	</xs:simpleContent>
			460	</xs:complexType>
			461	</xs:element>
		-+	463	<xs:element name="eastern_cancer_oncology_group">
			464	<xs:complexType>
			465	<xs:simpleContent>
			466	<xs:restriction base="utility:clinical_res_attributes">
			467	<xs:enumeration value="" />
			468	<xs:enumeration value="0" />
			469	<xs:enumeration value="1" />
			470	<xs:enumeration value="2" />
			471	<xs:enumeration value="3" />
			472	<xs:enumeration value="4" />
			473	<xs:attribute name="cde" type="xs:string" default="88" />
			474	<xs:attribute name="xsd_ver" type="xs:string" default="1.9" />
			475	<xs:attribute name="tier" type="xs:string" default="2" />
			476	</xs:restriction>
			477	</xs:simpleContent>
			478	</xs:complexType>
			479	</xs:element>
		-+	481	<xs:element name="primary_tumor_pathologic_spread" nillable="true">
			482	<xs:complexType>
			483	<xs:simpleContent>
			484	<xs:restriction base="utility:clinical_res_attributes">
			485	<xs:enumeration value="" />
			486	<xs:enumeration value="TX" />
			487	<xs:enumeration value="T0" />
			488	<xs:enumeration value="Tis" />
			489	<xs:enumeration value="T1" />
			490	<xs:enumeration value="T1a" />
			491	<xs:enumeration value="T1b" />
			492	<xs:enumeration value="T2" />
			493	<xs:enumeration value="T2a" />
			494	<xs:enumeration value="T2b" />
			495	<xs:enumeration value="T3" />
			496	<xs:enumeration value="T4" />
			497	<xs:attribute name="cde" type="xs:string" default="3045435" />
			498	<xs:attribute name="xsd_ver" type="xs:string" default="2.1" />
			499	<xs:attribute name="tier" type="xs:string" default="1" />
			500	</xs:restriction>
			501	</xs:simpleContent>
			502	</xs:complexType>
			503	</xs:element>
		-+	505	<xs:element name="lymphnode_pathologic_spread" nillable="true">
			506	<xs:complexType>
			507	<xs:simpleContent>
			508	<xs:restriction base="utility:clinical_res_attributes">
			509	<xs:enumeration value="" />
			510	<xs:enumeration value="NX" />
			511	<xs:enumeration value="N0" />
			512	<xs:enumeration value="N1" />
			513	<xs:enumeration value="N2" />
			514	<xs:enumeration value="N3" />
			515	<xs:attribute name="cde" type="xs:string" default="3065858" />
			516	<xs:attribute name="xsd_ver" type="xs:string" default="2.1" />
			517	<xs:attribute name="tier" type="xs:string" default="1" />
			518	</xs:restriction>
			519	</xs:simpleContent>
			520	</xs:complexType>
			521	</xs:element>
		-+	523	<xs:element name="distant_metastasis_pathologic_spread" nillable="true">
			524	<xs:complexType>
			525	<xs:simpleContent>
			526	<xs:restriction base="utility:clinical_res_attributes">
			527	<xs:enumeration value="" />
			528	<xs:enumeration value="M0" />
			529	<xs:enumeration value="M1" />
			530	<xs:enumeration value="M1a" />
			531	<xs:enumeration value="M1b" />
			532	<xs:enumeration value="MX" />
			533	<xs:attribute name="cde" type="xs:string" default="3045439" />
			534	<xs:attribute name="xsd_ver" type="xs:string" default="2.4" />
			535	<xs:attribute name="tier" type="xs:string" default="1" />
			536	</xs:restriction>
			537	</xs:simpleContent>
			538	</xs:complexType>
			539	</xs:element>
		-+	541	<xs:element name="tumor_stage" nillable="true">
			542	<xs:complexType>
			543	<xs:simpleContent>
			544	<xs:restriction base="utility:clinical_res_attributes">
			545	<xs:enumeration value="" />
			546	<xs:enumeration value="Stage I" />
			547	<xs:enumeration value="Stage IA" />
			548	<xs:enumeration value="Stage IB" />
			549	<xs:enumeration value="Stage II" />
			550	<xs:enumeration value="Stage IIA" />
			551	<xs:enumeration value="Stage IIB" />
			552	<xs:enumeration value="Stage III" />
			553	<xs:enumeration value="Stage IIIA" />
			554	<xs:enumeration value="Stage IIIB" />
			555	<xs:enumeration value="Stage IV" />
			556	<xs:attribute name="cde" type="xs:string" default="3065862" />
			557	<xs:attribute name="xsd_ver" type="xs:string" default="2.4" />
			558	<xs:attribute name="tier" type="xs:string" default="1" />
			559	</xs:restriction>
			560	</xs:simpleContent>
			561	</xs:complexType>
			562	</xs:element>

   
File: TCGA_BCR.LUAD_Clinical_FollowUp_v1.0.xsd  

1	<?xml version="1.0" encoding="utf-8" ?>	+-
4	<xs:schema elementFormDefault="qualified" version="2.5.0"	+-
5	xmlns:xs="http://www.w3.org/2001/XMLSchema"
6	xmlns:shared="http://tcga.nci/bcr/xml/clinical/shared/2.5"
7	xmlns:utility="http://tcga.nci/bcr/xml/utility/2.5"
8	xmlns:admin="http://tcga.nci/bcr/xml/administration/2.5"
9	xmlns="http://tcga.nci/bcr/xml/clinical/luad/followup/2.5/1.0"
10	targetNamespace="http://tcga.nci/bcr/xml/clinical/luad/followup/2.5/1.0"
11	xmlns:jaxb="http://java.sun.com/xml/ns/jaxb" jaxb:version="1.0" >
13	<xs:import schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/utility/2.5/TCGA_BCR.Utility.xsd" namespace="http://tcga.nci/bcr/xml/utility/2.5" />	+-
14	<xs:import schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/administration/2.5/TCGA_BCR.Administration.xsd" namespace="http://tcga.nci/bcr/xml/administration/2.5" />
15	<xs:import schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/shared/2.5/TCGA_BCR.Shared_Clinical_Elements.xsd" namespace="http://tcga.nci/bcr/xml/clinical/shared/2.5" />
17	<xs:annotation>	+-
18	<xs:appinfo>
19	<jaxb:globalBindings generateIsSetMethod="true" />
20	<jaxb:schemaBindings>
21	<jaxb:package name="nci.tcga.bcr.xml.jaxb.clinical.luad" />
22	</jaxb:schemaBindings>
23	</xs:appinfo>
24	</xs:annotation>
26	<xs:annotation>	+-
27	<xs:documentation xml:lang="en">Schema to define the elements of the TCGA Clinical Data Follow-up Form within the LUSC study.</xs:documentation>
28	</xs:annotation>
30	<xs:element name="follow_up_v1.0">	+-
31	<xs:complexType>
32	<xs:sequence>
33	<xs:element ref="shared:bcr_patient_barcode" />
34	<xs:element ref="shared:bcr_patient_uuid" />
35	<xs:element ref="shared:vital_status" />
36	<xs:choice>
37	<xs:sequence>
38	<xs:element ref="shared:day_of_last_followup" />
39	<xs:element ref="shared:month_of_last_followup" />
40	<xs:element ref="shared:year_of_last_followup" />
41	</xs:sequence>
42	<xs:element ref="shared:days_to_last_followup" />
43	</xs:choice>
44	<xs:choice>
45	<xs:sequence>
46	<xs:element ref="shared:day_of_death" />
47	<xs:element ref="shared:month_of_death" />
48	<xs:element ref="shared:year_of_death" />
49	</xs:sequence>
50	<xs:element ref="shared:days_to_death" />
51	</xs:choice>
52	<xs:choice>
53	<xs:sequence>
54	<xs:element ref="shared:day_of_new_tumor_event_after_initial_treatment" />
55	<xs:element ref="shared:month_of_new_tumor_event_after_initial_treatment" />
56	<xs:element ref="shared:year_of_new_tumor_event_after_initial_treatment" />
57	</xs:sequence>
58	<xs:element ref="shared:days_to_new_tumor_event_after_initial_treatment" />
59	</xs:choice>
60	<xs:element ref="shared:additional_surgery_locoregional_procedure" />
61	<xs:choice>
62	<xs:sequence>
63	<xs:element ref="shared:day_of_additional_surgery_locoregional_procedure" />
64	<xs:element ref="shared:month_of_additional_surgery_locoregional_procedure" />
65	<xs:element ref="shared:year_of_additional_surgery_locoregional_procedure" />
66	</xs:sequence>
67	<xs:element ref="shared:days_to_additional_surgery_locoregional_procedure" />
68	</xs:choice>
69	<xs:element ref="shared:person_neoplasm_cancer_status" />
70	<xs:element ref="shared:radiation_therapy" />
71	<xs:element ref="shared:additional_radiation_therapy" />
72	<xs:element ref="shared:targeted_molecular_therapy" />
73	<xs:element ref="shared:additional_pharmaceutical_therapy" />
74	<xs:element ref="shared:additional_surgery_metastatic_procedure" />
75	<xs:choice>
76	<xs:sequence>
77	<xs:element ref="shared:day_of_additional_surgery_metastatic_procedure" />
78	<xs:element ref="shared:month_of_additional_surgery_metastatic_procedure" />
79	<xs:element ref="shared:year_of_additional_surgery_metastatic_procedure" />
80	</xs:sequence>
81	<xs:element ref="shared:days_to_additional_surgery_metastatic_procedure" />
82	</xs:choice>
83	<xs:choice>
84	<xs:sequence>
85	<xs:element ref="shared:day_of_form_completion" />
86	<xs:element ref="shared:month_of_form_completion" />
87	<xs:element ref="shared:year_of_form_completion" />
88	</xs:sequence>
89	<xs:element ref="shared:days_to_form_completion" />
90	</xs:choice>
92	<xs:element ref="shared:followup_case_report_form_submission_reason" />	+-
94	<xs:element ref="shared:new_tumor_event_after_initial_treatment" />	+-
95	<xs:element ref="shared:followup_treatment_success" />
96	<xs:element ref="shared:karnofsky_performance_score" />
97	<xs:element ref="shared:eastern_cancer_oncology_group" />
98	<xs:element ref="shared:performance_status_scale_timing" />
99	</xs:sequence>
100	<xs:attribute name="version" type="xs:string" default="1.0" use="optional"/>
101	</xs:complexType>
102	</xs:element>
105	</xs:schema>	+-

   
File: TCGA_BCR.LUSC_Clinical.xsd  

4	<xs:schema elementFormDefault="qualified" version="2.5.0"	<>	4	<xs:schema elementFormDefault="qualified" version="2.4.4"
6	xmlns:utility="http://tcga.nci/bcr/xml/utility/2.5"	<>	6	xmlns:utility="http://tcga.nci/bcr/xml/utility/2.4"
7	xmlns:admin="http://tcga.nci/bcr/xml/administration/2.5"		7	xmlns:admin="http://tcga.nci/bcr/xml/administration/2.4"
8	xmlns:shared="http://tcga.nci/bcr/xml/clinical/shared/2.5"		8	xmlns:shared="http://tcga.nci/bcr/xml/clinical/shared/2.4"
9	xmlns:lusc_luad_shared="http://tcga.nci/bcr/xml/clinical/shared/lusc_luad/2.5"
10	xmlns:rad="http://tcga.nci/bcr/xml/clinical/radiation/2.5"		9	xmlns:rad="http://tcga.nci/bcr/xml/clinical/radiation/2.4"
11	xmlns:rx="http://tcga.nci/bcr/xml/clinical/pharmaceutical/2.5"		10	xmlns:rx="http://tcga.nci/bcr/xml/clinical/pharmaceutical/2.4"
12	xmlns:cqcf="http://tcga.nci/bcr/xml/clinical/cqcf/2.5"
13	xmlns:follow_up_v1.0="http://tcga.nci/bcr/xml/clinical/lusc/followup/2.5/1.0"
14	xmlns="http://tcga.nci/bcr/xml/clinical/lusc/2.5"		11	xmlns="http://tcga.nci/bcr/xml/clinical/lusc/2.4"
15	targetNamespace="http://tcga.nci/bcr/xml/clinical/lusc/2.5"		12	targetNamespace="http://tcga.nci/bcr/xml/clinical/lusc/2.4"
33	<xs:import namespace="http://tcga.nci/bcr/xml/utility/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/utility/2.5/TCGA_BCR.Utility.xsd" />	<>	28	<xs:import namespace="http://tcga.nci/bcr/xml/utility/2.4" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/utility/2.4/TCGA_BCR.Utility.xsd" />
34	<xs:import namespace="http://tcga.nci/bcr/xml/administration/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/administration/2.5/TCGA_BCR.Administration.xsd" />		29	<xs:import namespace="http://tcga.nci/bcr/xml/administration/2.4" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/administration/2.4/TCGA_BCR.Administration.xsd" />
35	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/shared/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/shared/2.5/TCGA_BCR.Shared_Clinical_Elements.xsd" />		30	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/shared/2.4" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/shared/2.4/TCGA_BCR.Shared_Clinical_Elements.xsd" />
36	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/radiation/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/radiation/2.5/TCGA_BCR.Radiation.xsd" />		31	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/radiation/2.4" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/radiation/2.4/TCGA_BCR.Radiation.xsd" />
37	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/pharmaceutical/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/pharmaceutical/2.5/TCGA_BCR.Pharmaceutical.xsd" />		32	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/pharmaceutical/2.4" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/pharmaceutical/2.4/TCGA_BCR.Pharmaceutical.xsd" />
38	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/cqcf/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/cqcf/2.5/TCGA_BCR.CQCF.xsd" />
39	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/lusc/followup/2.5/1.0" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/lusc/followup/2.5/TCGA_BCR.LUSC_Clinical_FollowUp_v1.0.xsd" />
40	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/shared/lusc_luad/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/shared/2.5/TCGA_BCR.Shared_Clinical_LUSC_LUAD_Elements.xsd" />
49	<xs:attribute name="schemaVersion" type="xs:decimal" use="required" fixed="2.5"/>	<>	41	<xs:attribute name="schemaVersion" type="xs:decimal" use="required" fixed="2.4"/>
57	<xs:element ref="lusc_luad_shared:histological_type" />	<>	49	<xs:element ref="histological_type" />
142	<xs:element ref="lusc_luad_shared:tumor_stage" />	<>	135	<xs:element ref="tumor_stage" />
143	<xs:element ref="lusc_luad_shared:primary_tumor_pathologic_spread" />		136	<xs:element ref="primary_tumor_pathologic_spread" />
144	<xs:element ref="lusc_luad_shared:lymphnode_pathologic_spread" />		137	<xs:element ref="lymphnode_pathologic_spread" />
145	<xs:element ref="lusc_luad_shared:distant_metastasis_pathologic_spread" />		138	<xs:element ref="distant_metastasis_pathologic_spread" />
146	<xs:element ref="shared:karnofsky_performance_score" />		139	<xs:element ref="karnofsky_performance_score" />
147	<xs:element ref="shared:eastern_cancer_oncology_group" />		140	<xs:element ref="eastern_cancer_oncology_group" />
148	<xs:element ref="lusc_luad_shared:tobacco_smoking_history_indicator" />		141	<xs:element ref="tobacco_smoking_history_indicator" />
149	<xs:element ref="lusc_luad_shared:year_of_tobacco_smoking_onset" />		142	<xs:element ref="year_of_tobacco_smoking_onset" />
150	<xs:element ref="shared:stopped_smoking_year" />		143	<xs:element ref="year_of_tobacco_smoking_cessation" />
151	<xs:element ref="shared:number_pack_years_smoked" />		144	<xs:element ref="number_pack_years_smoked" />
152	<xs:element ref="shared:anatomic_organ_subdivision" />		145	<xs:element ref="anatomic_organ_subdivision" />
153	<xs:element ref="lusc_luad_shared:diagnosis" />		146	<xs:element ref="diagnosis" />
154	<xs:element ref="lusc_luad_shared:location_in_lung_parenchyma" />		147	<xs:element ref="location_in_lung_parenchyma" />
155	<xs:element ref="shared:residual_tumor" />		148	<xs:element ref="residual_tumor" />
156	<xs:element ref="lusc_luad_shared:kras_mutation_found" />		149	<xs:element ref="kras_mutation_found" />
157	<xs:element ref="lusc_luad_shared:kras_gene_analysis_performed" />		150	<xs:element ref="kras_gene_analysis_performed" />
158	<xs:element ref="lusc_luad_shared:kras_mutation_result" />		151	<xs:element ref="kras_mutation_result" />
159	<xs:element ref="lusc_luad_shared:egfr_mutation_performed" />		152	<xs:element ref="egfr_mutation_performed" />
160	<xs:element ref="lusc_luad_shared:egfr_mutation_result" />		153	<xs:element ref="egfr_mutation_result" />
161	<xs:element ref="lusc_luad_shared:eml4_alk_translocation_performed" />		154	<xs:element ref="eml4_alk_translocation_performed" />
162	<xs:element ref="lusc_luad_shared:eml4_alk_translocation_result" />		155	<xs:element ref="eml4_alk_translocation_result" />
163	<xs:element ref="lusc_luad_shared:eml4_alk_translocation_method" />		156	<xs:element ref="eml4_alk_translocation_method" />
166		<>	159	</xs:sequence>
			160	</xs:complexType>
			161	</xs:element>
167	<xs:element ref="lusc_luad_shared:clinical_cqcf" />	<>	163	<xs:element name="egfr_mutation_result" nillable="true">
168			164	<xs:complexType mixed="true">
			165	<xs:simpleContent>
			166	<xs:restriction base="utility:clinical_res_attributes">
169	<xs:element name="follow_ups">		167	<xs:enumeration value="" />
			168	<xs:enumeration value="G719X" />
			169	<xs:enumeration value="Exon 19 Deletion" />
			170	<xs:enumeration value="Exon 20 Insertion" />
			171	<xs:enumeration value="T790M" />
			172	<xs:enumeration value="L858R" />
			173	<xs:enumeration value="L861Q" />
			174	<xs:enumeration value="Other" />
			175	<xs:attribute name="cde" type="xs:string" default="3147627" />
			176	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			177	<xs:attribute name="tier" type="xs:string" default="2" />
			178	</xs:restriction>
			179	</xs:simpleContent>
			180	</xs:complexType>
			181	</xs:element>
		<>	183	<xs:element name="eml4_alk_translocation_result" nillable="true">
			184	<xs:complexType mixed="true">
170	<xs:annotation>		185	<xs:simpleContent>
171	<xs:documentation>We are using namespaces and version numbers to distinguish one version of followup from another.</xs:documentation>		186	<xs:restriction base="utility:clinical_res_attributes">
			187	<xs:enumeration value="" />
			188	<xs:enumeration value="Variant 1" />
			189	<xs:enumeration value="Variant 2" />
			190	<xs:enumeration value="Variant 3" />
			191	<xs:enumeration value="Variant 4" />
			192	<xs:enumeration value="Variant 5" />
			193	<xs:attribute name="cde" type="xs:string" default="3139445" />
			194	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			195	<xs:attribute name="tier" type="xs:string" default="2" />
			196	</xs:restriction>
			197	</xs:simpleContent>
			198	</xs:complexType>
			199	</xs:element>
		-+	201	<xs:element name="eml4_alk_translocation_method" nillable="true">
			202	<xs:complexType mixed="true">
			203	<xs:simpleContent>
			204	<xs:restriction base="utility:clinical_res_attributes">
			205	<xs:enumeration value="" />
			206	<xs:enumeration value="IHC" />
			207	<xs:enumeration value="FISH" />
			208	<xs:enumeration value="RT-PCR" />
			209	<xs:enumeration value="Other" />
			210	<xs:attribute name="cde" type="xs:string" default="3139449" />
			211	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			212	<xs:attribute name="tier" type="xs:string" default="2" />
			213	</xs:restriction>
			214	</xs:simpleContent>
			215	</xs:complexType>
			216	</xs:element>
		<>	218	<xs:element name="egfr_mutation_performed" nillable="true">
			219	<xs:complexType>
			220	<xs:simpleContent>
			221	<xs:extension base="utility:yes_or_no">
			222	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			223	<xs:attribute name="cde" type="xs:string" default="3139429" />
			224	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			225	<xs:attribute name="tier" type="xs:string" default="1" />
172	</xs:annotation>		226	</xs:extension>
			227	</xs:simpleContent>
			228	</xs:complexType>
			229	</xs:element>
		-+	231	<xs:element name="eml4_alk_translocation_performed" nillable="true">
		<>	233	<xs:simpleContent>
			234	<xs:extension base="utility:yes_or_no">
			235	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			236	<xs:attribute name="cde" type="xs:string" default="3139437" />
			237	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			238	<xs:attribute name="tier" type="xs:string" default="1" />
			239	</xs:extension>
			240	</xs:simpleContent>
			241	</xs:complexType>
174	<xs:sequence>		242	</xs:element>
		-+	244	<xs:element name="histological_type" nillable="true">
			245	<xs:complexType mixed="true">
			246	<xs:simpleContent>
			247	<xs:restriction base="utility:clinical_res_attributes">
			248	<xs:attribute name="cde" type="xs:string" default="3081934" />
			249	<xs:attribute name="xsd_ver" type="xs:string" default="1.9" />
			250	<xs:attribute name="tier" type="xs:string" default="1" />
			251	</xs:restriction>
			252	</xs:simpleContent>
			253	</xs:complexType>
			254	</xs:element>
		-+	256	<xs:element name="diagnosis" nillable="true">
			257	<xs:complexType mixed="true">
			258	<xs:simpleContent>
			259	<xs:restriction base="utility:clinical_res_attributes">
			260	<xs:attribute name="cde" type="xs:string" default="3081932" />
			261	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			262	<xs:attribute name="tier" type="xs:string" default="1" />
			263	</xs:restriction>
			264	</xs:simpleContent>
			265	</xs:complexType>
			266	</xs:element>
		-+	268	<xs:element name="location_in_lung_parenchyma" nillable="true">
			269	<xs:complexType mixed="true">
			270	<xs:simpleContent>
			271	<xs:restriction base="utility:clinical_res_attributes">
			272	<xs:enumeration value="" />
			273	<xs:enumeration value="Peripheral Lung" />
			274	<xs:enumeration value="Central Lung" />
			275	<xs:attribute name="cde" type="xs:string" default="3139453" />
			276	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			277	<xs:attribute name="tier" type="xs:string" default="2" />
			278	</xs:restriction>
			279	</xs:simpleContent>
			280	</xs:complexType>
			281	</xs:element>
		-+	283	<xs:element name="anatomic_organ_subdivision" nillable="true">
			284	<xs:complexType mixed="true">
			285	<xs:simpleContent>
			286	<xs:restriction base="utility:clinical_res_attributes">
			287	<xs:enumeration value="" />
			288	<xs:enumeration value="R-Upper" />
			289	<xs:enumeration value="R-Middle" />
			290	<xs:enumeration value="R-Lower" />
			291	<xs:enumeration value="L-Upper" />
			292	<xs:enumeration value="L-Lower" />
			293	<xs:enumeration value="Bronchial" />
			294	<xs:enumeration value="Mediastinal" />
			295	<xs:attribute name="cde" type="xs:string" default="2008006" />
			296	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			297	<xs:attribute name="tier" type="xs:string" default="2" />
			298	</xs:restriction>
			299	</xs:simpleContent>
			300	</xs:complexType>
			301	</xs:element>
		-+	303	<xs:element name="kras_mutation_result" nillable="true">
			304	<xs:complexType mixed="true">
			305	<xs:simpleContent>
			306	<xs:restriction base="utility:clinical_res_attributes">
			307	<xs:enumeration value="" />
			308	<xs:enumeration value="G12A" />
			309	<xs:enumeration value="G12C" />
			310	<xs:enumeration value="G12D" />
			311	<xs:enumeration value="G12R" />
			312	<xs:enumeration value="G12S" />
			313	<xs:enumeration value="G12V" />
			314	<xs:enumeration value="G13D" />
			315	<xs:enumeration value="Other" />
			316	<xs:attribute name="cde" type="xs:string" default="3147614" />
			317	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			318	<xs:attribute name="tier" type="xs:string" default="2" />
			319	</xs:restriction>
			320	</xs:simpleContent>
			321	</xs:complexType>
			322	</xs:element>
		-+	324	<xs:element name="number_pack_years_smoked" nillable="true">
			325	<xs:complexType mixed="true">
			326	<xs:simpleContent>
			327	<xs:restriction base="utility:clinical_res_attributes">
			328	<xs:attribute name="cde" type="xs:string" default="2955385" />
			329	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			330	<xs:attribute name="tier" type="xs:string" default="1" />
			331	</xs:restriction>
			332	</xs:simpleContent>
			333	</xs:complexType>
			334	</xs:element>
		-+	336	<xs:element name="tobacco_smoking_history_indicator" nillable="true">
			337	<xs:complexType>
			338	<xs:simpleContent>
			339	<xs:restriction base="utility:clinical_res_attributes">
			340	<xs:enumeration value="" />
			341	<xs:enumeration value="Lifelong Non-smoker" />
			342	<xs:enumeration value="Current smoker" />
			343	<xs:enumeration value="Current reformed smoker for &gt; 15 years" />
			344	<xs:enumeration value="Current reformed smoker for &lt; or = 15 years" />
			345	<xs:attribute name="cde" type="xs:string" default="2181650" />
			346	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			347	<xs:attribute name="tier" type="xs:string" default="1" />
			348	</xs:restriction>
			349	</xs:simpleContent>
			350	</xs:complexType>
			351	</xs:element>
175	<xs:element ref="follow_up_v1.0:follow_up_v1.0" minOccurs="0" maxOccurs="unbounded" />	<>	353	<xs:element name="year_of_tobacco_smoking_onset" nillable="true">
			354	<xs:complexType mixed="true">
			355	<xs:simpleContent>
			356	<xs:extension base="utility:generic_year">
			357	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			358	<xs:attribute name="cde" type="xs:string" default="2228604" />
			359	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			360	<xs:attribute name="tier" type="xs:string" default="1" />
			361	</xs:extension>
			362	</xs:simpleContent>
			363	</xs:complexType>
176	</xs:sequence>		364	</xs:element>
		-+	366	<xs:element name="year_of_tobacco_smoking_cessation" nillable="true">
			367	<xs:complexType mixed="true">
			368	<xs:simpleContent>
			369	<xs:extension base="utility:generic_year">
			370	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			371	<xs:attribute name="cde" type="xs:string" default="2228610" />
			372	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			373	<xs:attribute name="tier" type="xs:string" default="1" />
			374	</xs:extension>
			375	</xs:simpleContent>
		<>	379	<xs:element name="kras_mutation_found" nillable="true">
			380	<xs:complexType>
			381	<xs:simpleContent>
			382	<xs:extension base="utility:yes_or_no">
			383	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			384	<xs:attribute name="cde" type="xs:string" default="2932340" />
			385	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			386	<xs:attribute name="tier" type="xs:string" default="1" />
			387	</xs:extension>
			388	</xs:simpleContent>
			389	</xs:complexType>
179	</xs:sequence>		390	</xs:element>
		-+	392	<xs:element name="kras_gene_analysis_performed" nillable="true">
			393	<xs:complexType>
			394	<xs:simpleContent>
			395	<xs:extension base="utility:yes_or_no">
			396	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			397	<xs:attribute name="cde" type="xs:string" default="3123147" />
			398	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			399	<xs:attribute name="tier" type="xs:string" default="1" />
			400	</xs:extension>
			401	</xs:simpleContent>
		-+	405	<xs:element name="residual_tumor" nillable="true">
			406	<xs:complexType>
			407	<xs:simpleContent>
			408	<xs:restriction base="utility:clinical_res_attributes">
			409	<xs:enumeration value="" />
			410	<xs:enumeration value="RX" />
			411	<xs:enumeration value="R0" />
			412	<xs:enumeration value="R1" />
			413	<xs:enumeration value="R2" />
			414	<xs:attribute name="cde" type="xs:string" default="2608702" />
			415	<xs:attribute name="xsd_ver" type="xs:string" default="1.11" />
			416	<xs:attribute name="tier" type="xs:string" default="1" />
			417	</xs:restriction>
			418	</xs:simpleContent>
			419	</xs:complexType>
			420	</xs:element>
		-+	422	<xs:element name="primary_therapy_outcome_success" nillable="true">
			423	<xs:complexType>
			424	<xs:simpleContent>
			425	<xs:restriction base="utility:clinical_res_attributes">
			426	<xs:enumeration value="" />
			427	<xs:enumeration value="PROGRESSIVE DISEASE" />
			428	<xs:enumeration value="STABLE DISEASE" />
			429	<xs:enumeration value="PARTIAL RESPONSE" />
			430	<xs:enumeration value="COMPLETE RESPONSE" />
			431	<xs:attribute name="cde" type="xs:string" default="2786727" />
			432	<xs:attribute name="xsd_ver" type="xs:string" default="1.11" />
			433	<xs:attribute name="tier" type="xs:string" default="2" />
			434	</xs:restriction>
			435	</xs:simpleContent>
			436	</xs:complexType>
			437	</xs:element>
		-+	439	<xs:element name="karnofsky_performance_score">
			440	<xs:complexType>
			441	<xs:simpleContent>
			442	<xs:restriction base="utility:clinical_res_attributes">
			443	<xs:enumeration value="" />
			444	<xs:enumeration value="0" />
			445	<xs:enumeration value="10" />
			446	<xs:enumeration value="20" />
			447	<xs:enumeration value="30" />
			448	<xs:enumeration value="40" />
			449	<xs:enumeration value="50" />
			450	<xs:enumeration value="60" />
			451	<xs:enumeration value="70" />
			452	<xs:enumeration value="80" />
			453	<xs:enumeration value="90" />
			454	<xs:enumeration value="100" />
			455	<xs:attribute name="cde" type="xs:string" default="2003853" />
			456	<xs:attribute name="xsd_ver" type="xs:string" default="1.8" />
			457	<xs:attribute name="tier" type="xs:string" default="2" />
			458	</xs:restriction>
			459	</xs:simpleContent>
			460	</xs:complexType>
			461	</xs:element>
		-+	463	<xs:element name="eastern_cancer_oncology_group">
			464	<xs:complexType>
			465	<xs:simpleContent>
			466	<xs:restriction base="utility:clinical_res_attributes">
			467	<xs:enumeration value="" />
			468	<xs:enumeration value="0" />
			469	<xs:enumeration value="1" />
			470	<xs:enumeration value="2" />
			471	<xs:enumeration value="3" />
			472	<xs:enumeration value="4" />
			473	<xs:attribute name="cde" type="xs:string" default="88" />
			474	<xs:attribute name="xsd_ver" type="xs:string" default="1.9" />
			475	<xs:attribute name="tier" type="xs:string" default="2" />
			476	</xs:restriction>
			477	</xs:simpleContent>
			478	</xs:complexType>
			479	</xs:element>
		-+	481	<xs:element name="primary_tumor_pathologic_spread" nillable="true">
			482	<xs:complexType>
			483	<xs:simpleContent>
			484	<xs:restriction base="utility:clinical_res_attributes">
			485	<xs:enumeration value="" />
			486	<xs:enumeration value="TX" />
			487	<xs:enumeration value="T0" />
			488	<xs:enumeration value="Tis" />
			489	<xs:enumeration value="T1" />
			490	<xs:enumeration value="T1a" />
			491	<xs:enumeration value="T1b" />
			492	<xs:enumeration value="T2" />
			493	<xs:enumeration value="T2a" />
			494	<xs:enumeration value="T2b" />
			495	<xs:enumeration value="T3" />
			496	<xs:enumeration value="T4" />
			497	<xs:attribute name="cde" type="xs:string" default="3045435" />
			498	<xs:attribute name="xsd_ver" type="xs:string" default="2.1" />
			499	<xs:attribute name="tier" type="xs:string" default="1" />
			500	</xs:restriction>
			501	</xs:simpleContent>
			502	</xs:complexType>
			503	</xs:element>
		-+	505	<xs:element name="lymphnode_pathologic_spread" nillable="true">
			506	<xs:complexType>
			507	<xs:simpleContent>
			508	<xs:restriction base="utility:clinical_res_attributes">
			509	<xs:enumeration value="" />
			510	<xs:enumeration value="NX" />
			511	<xs:enumeration value="N0" />
			512	<xs:enumeration value="N1" />
			513	<xs:enumeration value="N2" />
			514	<xs:enumeration value="N3" />
			515	<xs:attribute name="cde" type="xs:string" default="3065858" />
			516	<xs:attribute name="xsd_ver" type="xs:string" default="2.1" />
			517	<xs:attribute name="tier" type="xs:string" default="1" />
			518	</xs:restriction>
			519	</xs:simpleContent>
			520	</xs:complexType>
			521	</xs:element>
		-+	523	<xs:element name="distant_metastasis_pathologic_spread" nillable="true">
			524	<xs:complexType>
			525	<xs:simpleContent>
			526	<xs:restriction base="utility:clinical_res_attributes">
			527	<xs:enumeration value="" />
			528	<xs:enumeration value="M0" />
			529	<xs:enumeration value="M1" />
			530	<xs:enumeration value="M1a" />
			531	<xs:enumeration value="M1b" />
			532	<xs:enumeration value="MX" />
			533	<xs:attribute name="cde" type="xs:string" default="3045439" />
			534	<xs:attribute name="xsd_ver" type="xs:string" default="2.4" />
			535	<xs:attribute name="tier" type="xs:string" default="1" />
			536	</xs:restriction>
			537	</xs:simpleContent>
			538	</xs:complexType>
			539	</xs:element>
		-+	541	<xs:element name="tumor_stage" nillable="true">
			542	<xs:complexType>
			543	<xs:simpleContent>
			544	<xs:restriction base="utility:clinical_res_attributes">
			545	<xs:enumeration value="" />
			546	<xs:enumeration value="Stage I" />
			547	<xs:enumeration value="Stage IA" />
			548	<xs:enumeration value="Stage IB" />
			549	<xs:enumeration value="Stage II" />
			550	<xs:enumeration value="Stage IIA" />
			551	<xs:enumeration value="Stage IIB" />
			552	<xs:enumeration value="Stage III" />
			553	<xs:enumeration value="Stage IIIA" />
			554	<xs:enumeration value="Stage IIIB" />
			555	<xs:enumeration value="Stage IV" />
			556	<xs:attribute name="cde" type="xs:string" default="3065862" />
			557	<xs:attribute name="xsd_ver" type="xs:string" default="2.4" />
			558	<xs:attribute name="tier" type="xs:string" default="1" />
			559	</xs:restriction>
			560	</xs:simpleContent>
			561	</xs:complexType>
			562	</xs:element>

   
File: TCGA_BCR.LUSC_Clinical_FollowUp_v1.0.xsd  

1	<?xml version="1.0" encoding="utf-8" ?>	+-
4	<xs:schema elementFormDefault="qualified" version="2.5.0"	+-
5	xmlns:xs="http://www.w3.org/2001/XMLSchema"
6	xmlns:shared="http://tcga.nci/bcr/xml/clinical/shared/2.5"
7	xmlns:utility="http://tcga.nci/bcr/xml/utility/2.5"
8	xmlns:admin="http://tcga.nci/bcr/xml/administration/2.5"
9	xmlns="http://tcga.nci/bcr/xml/clinical/lusc/followup/2.5/1.0"
10	targetNamespace="http://tcga.nci/bcr/xml/clinical/lusc/followup/2.5/1.0"
11	xmlns:jaxb="http://java.sun.com/xml/ns/jaxb" jaxb:version="1.0" >
13	<xs:import schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/utility/2.5/TCGA_BCR.Utility.xsd" namespace="http://tcga.nci/bcr/xml/utility/2.5" />	+-
14	<xs:import schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/administration/2.5/TCGA_BCR.Administration.xsd" namespace="http://tcga.nci/bcr/xml/administration/2.5" />
15	<xs:import schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/shared/2.5/TCGA_BCR.Shared_Clinical_Elements.xsd" namespace="http://tcga.nci/bcr/xml/clinical/shared/2.5" />
17	<xs:annotation>	+-
18	<xs:appinfo>
19	<jaxb:globalBindings generateIsSetMethod="true" />
20	<jaxb:schemaBindings>
21	<jaxb:package name="nci.tcga.bcr.xml.jaxb.clinical.lusc" />
22	</jaxb:schemaBindings>
23	</xs:appinfo>
24	</xs:annotation>
26	<xs:annotation>	+-
27	<xs:documentation xml:lang="en">Schema to define the elements of the TCGA Clinical Data Follow-up Form within the LUSC study.</xs:documentation>
28	</xs:annotation>
30	<xs:element name="follow_up_v1.0">	+-
31	<xs:complexType>
32	<xs:sequence>
33	<xs:element ref="shared:bcr_patient_barcode" />
34	<xs:element ref="shared:bcr_patient_uuid" />
35	<xs:element ref="shared:vital_status" />
36	<xs:choice>
37	<xs:sequence>
38	<xs:element ref="shared:day_of_last_followup" />
39	<xs:element ref="shared:month_of_last_followup" />
40	<xs:element ref="shared:year_of_last_followup" />
41	</xs:sequence>
42	<xs:element ref="shared:days_to_last_followup" />
43	</xs:choice>
44	<xs:choice>
45	<xs:sequence>
46	<xs:element ref="shared:day_of_death" />
47	<xs:element ref="shared:month_of_death" />
48	<xs:element ref="shared:year_of_death" />
49	</xs:sequence>
50	<xs:element ref="shared:days_to_death" />
51	</xs:choice>
52	<xs:choice>
53	<xs:sequence>
54	<xs:element ref="shared:day_of_new_tumor_event_after_initial_treatment" />
55	<xs:element ref="shared:month_of_new_tumor_event_after_initial_treatment" />
56	<xs:element ref="shared:year_of_new_tumor_event_after_initial_treatment" />
57	</xs:sequence>
58	<xs:element ref="shared:days_to_new_tumor_event_after_initial_treatment" />
59	</xs:choice>
60	<xs:element ref="shared:additional_surgery_locoregional_procedure" />
61	<xs:choice>
62	<xs:sequence>
63	<xs:element ref="shared:day_of_additional_surgery_locoregional_procedure" />
64	<xs:element ref="shared:month_of_additional_surgery_locoregional_procedure" />
65	<xs:element ref="shared:year_of_additional_surgery_locoregional_procedure" />
66	</xs:sequence>
67	<xs:element ref="shared:days_to_additional_surgery_locoregional_procedure" />
68	</xs:choice>
69	<xs:element ref="shared:person_neoplasm_cancer_status" />
70	<xs:element ref="shared:radiation_therapy" />
71	<xs:element ref="shared:additional_radiation_therapy" />
72	<xs:element ref="shared:targeted_molecular_therapy" />
73	<xs:element ref="shared:additional_pharmaceutical_therapy" />
74	<xs:element ref="shared:additional_surgery_metastatic_procedure" />
75	<xs:choice>
76	<xs:sequence>
77	<xs:element ref="shared:day_of_additional_surgery_metastatic_procedure" />
78	<xs:element ref="shared:month_of_additional_surgery_metastatic_procedure" />
79	<xs:element ref="shared:year_of_additional_surgery_metastatic_procedure" />
80	</xs:sequence>
81	<xs:element ref="shared:days_to_additional_surgery_metastatic_procedure" />
82	</xs:choice>
83	<xs:choice>
84	<xs:sequence>
85	<xs:element ref="shared:day_of_form_completion" />
86	<xs:element ref="shared:month_of_form_completion" />
87	<xs:element ref="shared:year_of_form_completion" />
88	</xs:sequence>
89	<xs:element ref="shared:days_to_form_completion" />
90	</xs:choice>
92	<xs:element ref="shared:followup_case_report_form_submission_reason" />	+-
94	<xs:element ref="shared:new_tumor_event_after_initial_treatment" />	+-
95	<xs:element ref="shared:followup_treatment_success" />
96	<xs:element ref="shared:karnofsky_performance_score" />
97	<xs:element ref="shared:eastern_cancer_oncology_group" />
98	<xs:element ref="shared:performance_status_scale_timing" />
99	</xs:sequence>
100	<xs:attribute name="version" type="xs:string" default="1.0" use="optional"/>
101	</xs:complexType>
102	</xs:element>
106	</xs:schema>	+-

   
File: TCGA_BCR.OV_Clinical.xsd  

4	<xs:schema elementFormDefault="qualified" version="2.5.0"	<>	4	<xs:schema elementFormDefault="qualified" version="2.4.4"
6	xmlns:utility="http://tcga.nci/bcr/xml/utility/2.5"	<>	6	xmlns:utility="http://tcga.nci/bcr/xml/utility/2.4"
7	xmlns:admin="http://tcga.nci/bcr/xml/administration/2.5"		7	xmlns:admin="http://tcga.nci/bcr/xml/administration/2.4"
8	xmlns:shared="http://tcga.nci/bcr/xml/clinical/shared/2.5"		8	xmlns:shared="http://tcga.nci/bcr/xml/clinical/shared/2.4"
9	xmlns:rad="http://tcga.nci/bcr/xml/clinical/radiation/2.5"		9	xmlns:rad="http://tcga.nci/bcr/xml/clinical/radiation/2.4"
10	xmlns:rx="http://tcga.nci/bcr/xml/clinical/pharmaceutical/2.5"		10	xmlns:rx="http://tcga.nci/bcr/xml/clinical/pharmaceutical/2.4"
11	xmlns:follow_up_v1.0="http://tcga.nci/bcr/xml/clinical/ov/followup/2.5/1.0"
12	xmlns="http://tcga.nci/bcr/xml/clinical/ov/2.5"		11	xmlns="http://tcga.nci/bcr/xml/clinical/ov/2.4"
13	targetNamespace="http://tcga.nci/bcr/xml/clinical/ov/2.5"		12	targetNamespace="http://tcga.nci/bcr/xml/clinical/ov/2.4"
29	<xs:import namespace="http://tcga.nci/bcr/xml/utility/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/utility/2.5/TCGA_BCR.Utility.xsd" />	<>	28	<xs:import namespace="http://tcga.nci/bcr/xml/utility/2.4" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/utility/2.4/TCGA_BCR.Utility.xsd" />
30	<xs:import namespace="http://tcga.nci/bcr/xml/administration/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/administration/2.5/TCGA_BCR.Administration.xsd" />		29	<xs:import namespace="http://tcga.nci/bcr/xml/administration/2.4" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/administration/2.4/TCGA_BCR.Administration.xsd" />
31	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/shared/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/shared/2.5/TCGA_BCR.Shared_Clinical_Elements.xsd" />		30	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/shared/2.4" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/shared/2.4/TCGA_BCR.Shared_Clinical_Elements.xsd" />
32	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/radiation/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/radiation/2.5/TCGA_BCR.Radiation.xsd" />		31	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/radiation/2.4" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/radiation/2.4/TCGA_BCR.Radiation.xsd" />
33	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/pharmaceutical/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/pharmaceutical/2.5/TCGA_BCR.Pharmaceutical.xsd" />		32	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/pharmaceutical/2.4" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/pharmaceutical/2.4/TCGA_BCR.Pharmaceutical.xsd" />
34	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/ov/followup/2.5/1.0" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/ov/followup/2.5/TCGA_BCR.OV_Clinical_FollowUp_v1.0.xsd" />
43	<xs:attribute name="schemaVersion" type="xs:decimal" use="required" fixed="2.5"/>	<>	41	<xs:attribute name="schemaVersion" type="xs:decimal" use="required" fixed="2.4"/>
51	<xs:element ref="shared:tumor_histologic_subtype" />	<>	49	<xs:element ref="histological_type" />
		-+	89	<xs:element ref="radiation_therapy" />
		<>	109	<xs:element ref="shared:chemo_therapy" />
			110	<xs:element ref="shared:immuno_therapy" />
			111	<xs:element ref="shared:hormonal_therapy" />
99	<xs:element ref="shared:person_neoplasm_cancer_status" />		112	<xs:element ref="shared:targeted_molecular_therapy" />
102	<xs:element ref="shared:day_of_form_completion" />	<>	116	<xs:element ref="shared:day_of_tumor_progression" />
103	<xs:element ref="shared:month_of_form_completion" />		117	<xs:element ref="shared:month_of_tumor_progression" />
104	<xs:element ref="shared:year_of_form_completion" />		118	<xs:element ref="shared:year_of_tumor_progression" />
106	<xs:element ref="shared:days_to_form_completion" />	<>	121	<xs:element ref="shared:days_to_tumor_progression" />
108	<xs:element ref="shared:ethnicity" />	+-
		<>	124	<xs:choice>
			125	<xs:sequence>
110	<xs:element ref="shared:gynecologic_figo_staging_system" />		126	<xs:element ref="shared:day_of_tumor_recurrence" />
111			127	<xs:element ref="shared:month_of_tumor_recurrence" />
113	<xs:element ref="shared:karnofsky_performance_score" />	<>	128	<xs:element ref="shared:year_of_tumor_recurrence" />
			129	</xs:sequence>
114	<xs:element ref="shared:eastern_cancer_oncology_group" />	<>	131	<xs:element ref="shared:days_to_tumor_recurrence" />
			132	</xs:choice>
		<>	134	<xs:element ref="shared:ethnicity" />
115	<xs:element ref="shared:performance_status_scale_timing" />		135	<xs:element ref="site_of_tumor_first_recurrence" />
117	<xs:element ref="shared:neoplasm_histologic_grade" />	<>	137	<xs:element ref="tumor_grade" />
118	<xs:element ref="shared:residual_tumor" />		138	<xs:element ref="residual_tumor" />
		-+	140	<xs:element ref="primary_therapy_outcome_success" />
		-+	143	<xs:element ref="additional_chemo_therapy" />
			144	<xs:element ref="additional_immuno_therapy" />
123	<xs:element ref="shared:anatomic_organ_subdivision" />	<>	146	<xs:element ref="additional_drug_therapy" />
124	<xs:element ref="shared:initial_pathologic_diagnosis_method" />		147	<xs:element ref="anatomic_organ_subdivision" />
125	<xs:element ref="shared:venous_invasion" />		148	<xs:element ref="initial_pathologic_diagnosis_method" />
126	<xs:element ref="shared:lymphatic_invasion" />		149	<xs:element ref="shared:person_neoplasm_cancer_status" />
127	<xs:element ref="rx:drugs" />		150	<xs:element ref="drugs" />
128	<xs:element ref="rad:radiations" />		151	<xs:element ref="radiations" />
130	<xs:element name="follow_ups">	<>	152	<xs:element ref="examinations" />
131	<xs:annotation>
132	<xs:documentation>We are using namespaces and version numbers to distinguish one version of followup from another.</xs:documentation>
133	</xs:annotation>
134	<xs:complexType>
135	<xs:sequence>		153	<xs:element ref="surgeries" />
136	<xs:element ref="follow_up_v1.0:follow_up_v1.0" minOccurs="0" maxOccurs="unbounded" />
		<>	158	<xs:element name="histological_type" nillable="true">
			159	<xs:complexType mixed="true">
			160	<xs:simpleContent>
			161	<xs:restriction base="utility:clinical_res_attributes">
			162	<xs:attribute name="cde" type="xs:string" default="2831122" />
			163	<xs:attribute name="xsd_ver" type="xs:string" default="1.9" />
			164	<xs:attribute name="tier" type="xs:string" default="1" />
141	</xs:sequence>		165	</xs:restriction>
			166	</xs:simpleContent>
145	<xs:element name="other_method_of_initial_pathological_diagnosis" nillable="true">	<>	170	<xs:element name="site_of_tumor_first_recurrence" nillable="true">
148	<xs:extension base="xs:string">	<>
149	<xs:attributeGroup ref="utility:common_ext_attribute_group" />		173	<xs:restriction base="utility:clinical_res_attributes">
			174	<xs:enumeration value="" />
			175	<xs:enumeration value="LOCO-REGIONAL" />
			176	<xs:enumeration value="METASTASIS" />
			177	<xs:enumeration value="LOCOREGIONAL AND METASTASIS" />
150	<xs:attribute name="cde" type="xs:string" default="2757948" />		178	<xs:attribute name="cde" type="xs:string" default="2791194" />
151	<xs:attribute name="xsd_ver" type="xs:string" default="2.5" />		179	<xs:attribute name="xsd_ver" type="xs:string" default="1.11" />
153	</xs:extension>	<>	181	</xs:restriction>
163	<xs:enumeration value="I" />	+-
167	<xs:enumeration value="II" />	+-
171	<xs:enumeration value="III" />	+-
		-+	209	<xs:element name="tumor_grade" nillable="true">
			210	<xs:complexType>
			211	<xs:simpleContent>
			212	<xs:restriction base="utility:clinical_res_attributes">
			213	<xs:enumeration value="" />
			214	<xs:enumeration value="GX" />
			215	<xs:enumeration value="GB" />
			216	<xs:enumeration value="G1" />
			217	<xs:enumeration value="G2" />
			218	<xs:enumeration value="G3" />
			219	<xs:enumeration value="G4" />
			220	<xs:attribute name="cde" type="xs:string" default="2785839" />
			221	<xs:attribute name="xsd_ver" type="xs:string" default="1.11" />
			222	<xs:attribute name="tier" type="xs:string" default="1" />
			223	</xs:restriction>
			224	</xs:simpleContent>
			225	</xs:complexType>
			226	</xs:element>
		-+	228	<xs:element name="residual_tumor" nillable="true">
			229	<xs:complexType>
			230	<xs:simpleContent>
			231	<xs:restriction base="utility:clinical_res_attributes">
			232	<xs:enumeration value="" />
			233	<xs:enumeration value="RX" />
			234	<xs:enumeration value="R0" />
			235	<xs:enumeration value="R1" />
			236	<xs:enumeration value="R2" />
			237	<xs:attribute name="cde" type="xs:string" default="2608702" />
			238	<xs:attribute name="xsd_ver" type="xs:string" default="1.11" />
			239	<xs:attribute name="tier" type="xs:string" default="1" />
			240	</xs:restriction>
			241	</xs:simpleContent>
			242	</xs:complexType>
			243	</xs:element>
		-+	245	<xs:element name="primary_therapy_outcome_success" nillable="true">
			246	<xs:complexType>
			247	<xs:simpleContent>
			248	<xs:restriction base="utility:clinical_res_attributes">
			249	<xs:enumeration value="" />
			250	<xs:enumeration value="PROGRESSIVE DISEASE" />
			251	<xs:enumeration value="STABLE DISEASE" />
			252	<xs:enumeration value="PARTIAL RESPONSE" />
			253	<xs:enumeration value="COMPLETE RESPONSE" />
			254	<xs:attribute name="cde" type="xs:string" default="2786727" />
			255	<xs:attribute name="xsd_ver" type="xs:string" default="1.11" />
			256	<xs:attribute name="tier" type="xs:string" default="2" />
			257	</xs:restriction>
			258	</xs:simpleContent>
			259	</xs:complexType>
			260	</xs:element>
		-+	277	<xs:element name="additional_chemo_therapy" nillable="true">
			278	<xs:complexType>
			279	<xs:simpleContent>
			280	<xs:extension base="utility:yes_or_no">
			281	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			282	<xs:attribute name="cde" type="xs:string" default="2650626" />
			283	<xs:attribute name="xsd_ver" type="xs:string" default="1.9" />
			284	<xs:attribute name="tier" type="xs:string" default="2" />
			285	</xs:extension>
			286	</xs:simpleContent>
			287	</xs:complexType>
			288	</xs:element>
		-+	290	<xs:element name="additional_immuno_therapy" nillable="true">
			291	<xs:complexType>
			292	<xs:simpleContent>
			293	<xs:extension base="utility:yes_or_no">
			294	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			295	<xs:attribute name="cde" type="xs:string" default="2759828" />
			296	<xs:attribute name="xsd_ver" type="xs:string" default="1.9" />
			297	<xs:attribute name="tier" type="xs:string" default="2" />
			298	</xs:extension>
			299	</xs:simpleContent>
			300	</xs:complexType>
			301	</xs:element>
		-+	303	<xs:element name="additional_drug_therapy" nillable="true">
			304	<xs:complexType>
			305	<xs:simpleContent>
			306	<xs:extension base="utility:yes_or_no">
			307	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			308	<xs:attribute name="cde" type="xs:string" default="2786150" />
			309	<xs:attribute name="xsd_ver" type="xs:string" default="1.9" />
			310	<xs:attribute name="tier" type="xs:string" default="2" />
			311	</xs:extension>
			312	</xs:simpleContent>
			313	</xs:complexType>
			314	</xs:element>
		-+	316	<xs:element name="anatomic_organ_subdivision" nillable="true">
			317	<xs:complexType mixed="true">
			318	<xs:simpleContent>
			319	<xs:restriction base="utility:clinical_res_attributes">
			320	<xs:attribute name="cde" type="xs:string" default="2008006" />
			321	<xs:attribute name="xsd_ver" type="xs:string" default="1.9" />
			322	<xs:attribute name="tier" type="xs:string" default="2" />
			323	</xs:restriction>
			324	</xs:simpleContent>
			325	</xs:complexType>
			326	</xs:element>
		-+	328	<xs:element name="initial_pathologic_diagnosis_method" nillable="true">
			329	<xs:complexType>
			330	<xs:simpleContent>
			331	<xs:restriction base="utility:clinical_res_attributes">
			332	<xs:enumeration value="" />
			333	<xs:enumeration value="CYTOLOGY" />
			334	<xs:enumeration value="FINE NEEDLE ASPIRATION BIOPSY" />
			335	<xs:enumeration value="INCISION BIOPSY" />
			336	<xs:enumeration value="EXCISIONAL BIOPSY" />
			337	<xs:enumeration value="TUMOR RESECTION" />
			338	<xs:enumeration value="OTHER METHOD, SPECIFY IN NOTES" />
			339	<xs:attribute name="cde" type="xs:string" default="2757941" />
			340	<xs:attribute name="xsd_ver" type="xs:string" default="1.9" />
			341	<xs:attribute name="tier" type="xs:string" default="2" />
			342	</xs:restriction>
			343	</xs:simpleContent>
			344	</xs:complexType>
			345	</xs:element>
		-+	347	<xs:element name="radiation_therapy">
			348	<xs:complexType>
			349	<xs:simpleContent>
			350	<xs:extension base="utility:yes_or_no">
			351	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			352	<xs:attribute name="cde" type="xs:string" default="2005312" />
			353	<xs:attribute name="xsd_ver" type="xs:string" default="1.9" />
			354	<xs:attribute name="tier" type="xs:string" default="1" />
			355	</xs:extension>
			356	</xs:simpleContent>
			357	</xs:complexType>
			358	</xs:element>
		-+	360	<xs:element name="drugs">
			361	<xs:complexType>
			362	<xs:sequence minOccurs="0" maxOccurs="unbounded">
			363	<xs:element ref="drug" />
			364	</xs:sequence>
			365	</xs:complexType>
			366	</xs:element>
		-+	368	<xs:element name="drug">
			369	<xs:complexType>
			370	<xs:sequence>
			371	<xs:element ref="rx:bcr_drug_barcode" />
			372	<xs:element ref="rx:bcr_drug_uuid" />
			373	<xs:element ref="rx:drug_category" />
			374	<xs:element ref="rx:total_dose" />
			375	<xs:element ref="rx:total_dose_units" />
			376	<xs:element ref="rx:number_cycles" />
		-+	378	<xs:choice>
			379	<xs:sequence>
			380	<xs:element ref="rx:day_of_drug_therapy_start" />
			381	<xs:element ref="rx:month_of_drug_therapy_start" />
			382	<xs:element ref="rx:year_of_drug_therapy_start" />
			383	</xs:sequence>
		-+	385	<xs:element ref="rx:days_to_drug_therapy_start" />
			386	</xs:choice>
		-+	388	<xs:choice>
			389	<xs:sequence>
			390	<xs:element ref="rx:day_of_drug_therapy_end" />
			391	<xs:element ref="rx:month_of_drug_therapy_end" />
			392	<xs:element ref="rx:year_of_drug_therapy_end" />
			393	</xs:sequence>
		-+	395	<xs:element ref="rx:days_to_drug_therapy_end" />
			396	</xs:choice>
		-+	398	<xs:element ref="initial_course" />
			399	<xs:element ref="rx:drug_name" />
			400	<xs:element ref="shared:regimen_indication" />
			401	<xs:element ref="shared:regimen_indication_notes" />
			402	<xs:element ref="route_of_administration" />
			403	<xs:element ref="route_of_administration_notes" />
			404	<xs:element ref="rx:therapy_ongoing" />
			405	</xs:sequence>
			406	</xs:complexType>
			407	</xs:element>
		-+	409	<xs:element name="bcr_drug_barcode">
			410	<xs:complexType>
			411	<xs:simpleContent>
			412	<xs:extension base="xs:NCName">
			413	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			414	<xs:attribute name="xsd_ver" type="xs:string" default="1.15" />
			415	</xs:extension>
			416	</xs:simpleContent>
			417	</xs:complexType>
			418	</xs:element>
		-+	420	<xs:element name="number_cycles">
			421	<xs:complexType>
			422	<xs:simpleContent>
			423	<xs:extension base="xs:string">
			424	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			425	<xs:attribute name="cde" type="xs:string" default="62590" />
			426	<xs:attribute name="xsd_ver" type="xs:string" default="1.8" />
			427	<xs:attribute name="tier" type="xs:string" default="2" />
			428	</xs:extension>
			429	</xs:simpleContent>
			430	</xs:complexType>
			431	</xs:element>
		-+	433	<xs:element name="drug_category">
			434	<xs:complexType>
			435	<xs:simpleContent>
			436	<xs:restriction base="utility:clinical_res_attributes">
			437	<xs:enumeration value="" />
			438	<xs:enumeration value="CHEMO" />
			439	<xs:enumeration value="HORMONAL" />
			440	<xs:enumeration value="IMMUNO" />
			441	<xs:enumeration value="TARGETED" />
			442	<xs:attribute name="cde" type="xs:string" default="729" />
			443	<xs:attribute name="xsd_ver" type="xs:string" default="1.8" />
			444	<xs:attribute name="tier" type="xs:string" default="2" />
			445	</xs:restriction>
			446	</xs:simpleContent>
			447	</xs:complexType>
			448	</xs:element>
		-+	450	<xs:element name="initial_course">
			451	<xs:complexType>
			452	<xs:simpleContent>
			453	<xs:extension base="utility:yes_or_no">
			454	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			455	<xs:attribute name="cde" type="xs:string" default="2003586" />
			456	<xs:attribute name="xsd_ver" type="xs:string" default="1.8" />
			457	<xs:attribute name="tier" type="xs:string" default="2" />
			458	</xs:extension>
			459	</xs:simpleContent>
			460	</xs:complexType>
			461	</xs:element>
		-+	463	<xs:element name="route_of_administration">
			464	<xs:complexType>
			465	<xs:simpleContent>
			466	<xs:restriction base="utility:clinical_res_attributes">
			467	<xs:enumeration value="" />
			468	<xs:enumeration value="ORAL" />
			469	<xs:enumeration value="INTRAVENOUS (IV)" />
			470	<xs:enumeration value="INTRATUMORAL" />
			471	<xs:enumeration value="INTRA-PERITONEAL (IP)" />
			472	<xs:enumeration value="IV AND IP" />
			473	<xs:enumeration value="OTHER: SPECIFY IN NOTES" />
			474	<xs:attribute name="cde" type="xs:string" default="2003586" />
			475	<xs:attribute name="xsd_ver" type="xs:string" default="1.12" />
			476	<xs:attribute name="tier" type="xs:string" default="2" />
			477	</xs:restriction>
			478	</xs:simpleContent>
			479	</xs:complexType>
			480	</xs:element>
		-+	482	<xs:element name="route_of_administration_notes">
			483	<xs:complexType mixed="true">
			484	<xs:simpleContent>
			485	<xs:restriction base="utility:clinical_res_attributes">
			486	<xs:attribute name="cde" type="xs:string" default="2190504" />
			487	<xs:attribute name="xsd_ver" type="xs:string" default="1.12" />
			488	<xs:attribute name="tier" type="xs:string" default="2" />
			489	</xs:restriction>
			490	</xs:simpleContent>
			491	</xs:complexType>
			492	</xs:element>
		-+	494	<xs:element name="radiations">
			495	<xs:complexType>
			496	<xs:sequence minOccurs="0" maxOccurs="unbounded">
			497	<xs:element ref="radiation" />
			498	</xs:sequence>
			499	</xs:complexType>
			500	</xs:element>
		-+	502	<xs:element name="radiation">
			503	<xs:complexType>
			504	<xs:sequence>
			505	<xs:element ref="rad:bcr_radiation_barcode" />
			506	<xs:element ref="rad:bcr_radiation_uuid"/>
		-+	508	<xs:choice>
			509	<xs:sequence>
			510	<xs:element ref="rad:day_of_radiation_therapy_start" />
			511	<xs:element ref="rad:month_of_radiation_therapy_start" />
			512	<xs:element ref="rad:year_of_radiation_therapy_start" />
			513	</xs:sequence>
		-+	515	<xs:element ref="rad:days_to_radiation_therapy_start" />
			516	</xs:choice>
		-+	518	<xs:choice>
			519	<xs:sequence>
			520	<xs:element ref="rad:day_of_radiation_therapy_end" />
			521	<xs:element ref="rad:month_of_radiation_therapy_end" />
			522	<xs:element ref="rad:year_of_radiation_therapy_end" />
			523	</xs:sequence>
		-+	525	<xs:element ref="rad:days_to_radiation_therapy_end" />
			526	</xs:choice>
		-+	528	<xs:element ref="rad:radiation_type" />
			529	<xs:element ref="rad:radiation_type_notes" />
			530	<xs:element ref="rad:radiation_dosage" />
			531	<xs:element ref="rad:units" />
			532	<xs:element ref="rad:numfractions" />
			533	<xs:element ref="anatomic_treatment_site" />
			534	<xs:element ref="shared:regimen_indication" />
			535	<xs:element ref="shared:regimen_indication_notes" />
			536	<xs:element ref="rad:radiation_treatment_ongoing" />
			537	</xs:sequence>
			538	</xs:complexType>
			539	</xs:element>
		-+	541	<xs:element name="bcr_radiation_barcode">
			542	<xs:complexType>
			543	<xs:simpleContent>
			544	<xs:extension base="xs:NCName">
			545	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			546	<xs:attribute name="xsd_ver" type="xs:string" default="1.15" />
			547	</xs:extension>
			548	</xs:simpleContent>
			549	</xs:complexType>
			550	</xs:element>
		-+	552	<xs:element name="radiation_treatment_ongoing" nillable="true">
			553	<xs:complexType>
			554	<xs:simpleContent>
			555	<xs:extension base="utility:yes_or_no">
			556	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			557	<xs:attribute name="cde" type="xs:string" default="2842745" />
			558	<xs:attribute name="xsd_ver" type="xs:string" default="1.12" />
			559	<xs:attribute name="tier" type="xs:string" default="2" />
			560	</xs:extension>
			561	</xs:simpleContent>
			562	</xs:complexType>
			563	</xs:element>
		-+	565	<xs:element name="anatomic_treatment_site">
			566	<xs:complexType>
			567	<xs:simpleContent>
			568	<xs:extension base="xs:string">
			569	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			570	<xs:attribute name="cde" type="xs:string" default="2793522" />
			571	<xs:attribute name="xsd_ver" type="xs:string" default="1.8" />
			572	<xs:attribute name="tier" type="xs:string" default="2" />
			573	</xs:extension>
			574	</xs:simpleContent>
			575	</xs:complexType>
			576	</xs:element>
		-+	578	<xs:element name="examinations">
			579	<xs:complexType>
			580	<xs:sequence minOccurs="0" maxOccurs="unbounded">
			581	<xs:element ref="examination" />
			582	</xs:sequence>
			583	</xs:complexType>
			584	</xs:element>
		-+	586	<xs:element name="examination">
			587	<xs:complexType>
			588	<xs:sequence>
			589	<xs:element ref="bcr_examination_barcode" />
			590	<xs:element ref="karnofsky_performance_score" />
			591	<xs:element ref="eastern_cancer_oncology_group" />
			592	<xs:element ref="progression_status" />
			593	<xs:element ref="shared:performance_status_scale_timing" />
			594	<xs:element ref="shared:progression_determined_by" />
			595	<xs:element ref="shared:progression_determined_by_notes" />
			596	</xs:sequence>
			597	</xs:complexType>
			598	</xs:element>
		-+	600	<xs:element name="bcr_examination_barcode">
			601	<xs:complexType>
			602	<xs:simpleContent>
			603	<xs:extension base="xs:NCName">
			604	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			605	<xs:attribute name="xsd_ver" type="xs:string" default="1.15" />
			606	</xs:extension>
			607	</xs:simpleContent>
			608	</xs:complexType>
			609	</xs:element>
		-+	611	<xs:element name="karnofsky_performance_score">
			612	<xs:complexType>
			613	<xs:simpleContent>
			614	<xs:restriction base="utility:clinical_res_attributes">
			615	<xs:enumeration value="" />
			616	<xs:enumeration value="0" />
			617	<xs:enumeration value="10" />
			618	<xs:enumeration value="20" />
			619	<xs:enumeration value="30" />
			620	<xs:enumeration value="40" />
			621	<xs:enumeration value="50" />
			622	<xs:enumeration value="60" />
			623	<xs:enumeration value="70" />
			624	<xs:enumeration value="80" />
			625	<xs:enumeration value="90" />
			626	<xs:enumeration value="100" />
			627	<xs:attribute name="cde" type="xs:string" default="2003853" />
			628	<xs:attribute name="xsd_ver" type="xs:string" default="1.8" />
			629	<xs:attribute name="tier" type="xs:string" default="2" />
			630	</xs:restriction>
			631	</xs:simpleContent>
			632	</xs:complexType>
			633	</xs:element>
		-+	635	<xs:element name="eastern_cancer_oncology_group">
			636	<xs:complexType>
			637	<xs:simpleContent>
			638	<xs:restriction base="utility:clinical_res_attributes">
			639	<xs:enumeration value="" />
			640	<xs:enumeration value="0" />
			641	<xs:enumeration value="1" />
			642	<xs:enumeration value="2" />
			643	<xs:enumeration value="3" />
			644	<xs:enumeration value="4" />
			645	<xs:enumeration value="5" />
			646	<xs:attribute name="cde" type="xs:string" default="88" />
			647	<xs:attribute name="xsd_ver" type="xs:string" default="1.9" />
			648	<xs:attribute name="tier" type="xs:string" default="2" />
			649	</xs:restriction>
			650	</xs:simpleContent>
			651	</xs:complexType>
			652	</xs:element>
		-+	654	<xs:element name="progression_status">
			655	<xs:complexType>
			656	<xs:simpleContent>
			657	<xs:extension base="utility:yes_or_no">
			658	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			659	<xs:attribute name="cde" type="xs:string" default="2673787" />
			660	<xs:attribute name="xsd_ver" type="xs:string" default="1.8" />
			661	<xs:attribute name="tier" type="xs:string" default="2" />
			662	</xs:extension>
			663	</xs:simpleContent>
			664	</xs:complexType>
			665	</xs:element>
		-+	679	</xs:restriction>
			680	</xs:simpleContent>
			681	</xs:complexType>
			682	</xs:element>
		-+	684	<xs:element name="progression_determined_by">
			685	<xs:complexType>
			686	<xs:simpleContent>
			687	<xs:restriction base="utility:clinical_res_attributes">
			688	<xs:enumeration value="" />
			689	<xs:enumeration value="LABORATORY" />
			690	<xs:enumeration value="PATHOLOGY" />
			691	<xs:enumeration value="RADIATION" />
			692	<xs:enumeration value="PHYSICAL EXAMINATION" />
			693	<xs:enumeration value="IMAGING STUDY" />
			694	<xs:enumeration value="MOLECULAR MARKER(S)" />
			695	<xs:enumeration value="FIRST SEEN AT FURTHER SURGERY" />
			696	<xs:enumeration value="OTHER METHOD: SPECIFY IN NOTES" />
			697	<xs:attribute name="cde" type="xs:string" default="2786205" />
			698	<xs:attribute name="xsd_ver" type="xs:string" default="1.9" />
			699	<xs:attribute name="tier" type="xs:string" default="2" />
			700	</xs:restriction>
			701	</xs:simpleContent>
			702	</xs:complexType>
			703	</xs:element>
		-+	705	<xs:element name="progression_determined_by_notes">
			706	<xs:complexType mixed="true">
			707	<xs:simpleContent>
			708	<xs:restriction base="utility:clinical_res_attributes">
			709	<xs:attribute name="cde" type="xs:string" default="2786210" />
			710	<xs:attribute name="xsd_ver" type="xs:string" default="1.9" />
			711	<xs:attribute name="tier" type="xs:string" default="2" />
			712	</xs:restriction>
			713	</xs:simpleContent>
			714	</xs:complexType>
			715	</xs:element>
		-+	717	<xs:element name="surgeries">
			718	<xs:complexType>
			719	<xs:sequence minOccurs="0" maxOccurs="unbounded">
			720	<xs:element ref="surgery" />
			721	</xs:sequence>
			722	</xs:complexType>
			723	</xs:element>
		-+	725	<xs:element name="surgery">
			726	<xs:complexType>
			727	<xs:sequence>
			728	<xs:element ref="bcr_surgery_barcode" />
		-+	730	<xs:choice>
			731	<xs:sequence>
			732	<xs:element ref="day_of_procedure" />
			733	<xs:element ref="month_of_procedure" />
			734	<xs:element ref="year_of_procedure" />
			735	</xs:sequence>
		-+	737	<xs:element ref="days_to_procedure" />
			738	</xs:choice>
		-+	740	<xs:element ref="procedure_type" />
			741	</xs:sequence>
			742	</xs:complexType>
			743	</xs:element>
		-+	745	<xs:element name="bcr_surgery_barcode">
			746	<xs:complexType>
			747	<xs:simpleContent>
			748	<xs:extension base="xs:NCName">
			749	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			750	<xs:attribute name="cde" type="xs:string" default="2003586" />
			751	<xs:attribute name="xsd_ver" type="xs:string" default="1.8" />
			752	</xs:extension>
			753	</xs:simpleContent>
			754	</xs:complexType>
			755	</xs:element>
		-+	757	<xs:element name="day_of_procedure">
			758	<xs:complexType mixed="true">
			759	<xs:simpleContent>
			760	<xs:restriction base="utility:clinical_res_attributes">
			761	<xs:attribute name="cde" type="xs:string" default="2896965" />
			762	<xs:attribute name="xsd_ver" type="xs:string" default="1.12" />
			763	<xs:attribute name="tier" type="xs:string" default="1" />
			764	</xs:restriction>
			765	</xs:simpleContent>
			766	</xs:complexType>
			767	</xs:element>
		-+	769	<xs:element name="month_of_procedure">
			770	<xs:complexType mixed="true">
			771	<xs:simpleContent>
			772	<xs:restriction base="utility:clinical_res_attributes">
			773	<xs:attribute name="cde" type="xs:string" default="2896963" />
			774	<xs:attribute name="xsd_ver" type="xs:string" default="1.12" />
			775	<xs:attribute name="tier" type="xs:string" default="1" />
			776	</xs:restriction>
			777	</xs:simpleContent>
			778	</xs:complexType>
			779	</xs:element>
		-+	781	<xs:element name="year_of_procedure">
			782	<xs:complexType mixed="true">
			783	<xs:simpleContent>
			784	<xs:restriction base="utility:clinical_res_attributes">
			785	<xs:attribute name="cde" type="xs:string" default="2896985" />
			786	<xs:attribute name="xsd_ver" type="xs:string" default="1.12" />
			787	<xs:attribute name="tier" type="xs:string" default="1" />
			788	</xs:restriction>
			789	</xs:simpleContent>
			790	</xs:complexType>
			791	</xs:element>
		-+	793	<xs:element name="procedure_type">
			794	<xs:complexType mixed="true">
			795	<xs:simpleContent>
			796	<xs:restriction base="utility:clinical_res_attributes">
			797	<xs:attribute name="cde" type="xs:string" default="2199761" />
			798	<xs:attribute name="xsd_ver" type="xs:string" default="1.9" />
			799	<xs:attribute name="tier" type="xs:string" default="2" />
			800	</xs:restriction>
			801	</xs:simpleContent>
			802	</xs:complexType>
			803	</xs:element>
		-+	805	<xs:element name="days_to_drug_treatment_start">
			806	<xs:complexType mixed="true">
			807	<xs:simpleContent>
			808	<xs:restriction base="utility:clinical_res_attributes">
			809	<xs:attribute name="cde" type="xs:string" default="" />
			810	<xs:attribute name="xsd_ver" type="xs:string" default="" />
			811	<xs:attribute name="tier" type="xs:string" default="1" />
			812	</xs:restriction>
			813	</xs:simpleContent>
			814	</xs:complexType>
			815	</xs:element>
		-+	817	<xs:element name="days_to_drug_treatment_end">
			818	<xs:complexType mixed="true">
			819	<xs:simpleContent>
			820	<xs:restriction base="utility:clinical_res_attributes">
			821	<xs:attribute name="cde" type="xs:string" default="" />
			822	<xs:attribute name="xsd_ver" type="xs:string" default="" />
			823	<xs:attribute name="tier" type="xs:string" default="1" />
			824	</xs:restriction>
			825	</xs:simpleContent>
			826	</xs:complexType>
			827	</xs:element>
		-+	829	<xs:element name="days_to_radiation_treatment_start">
			830	<xs:complexType mixed="true">
			831	<xs:simpleContent>
			832	<xs:restriction base="utility:clinical_res_attributes">
			833	<xs:attribute name="cde" type="xs:string" default="" />
			834	<xs:attribute name="xsd_ver" type="xs:string" default="" />
			835	<xs:attribute name="tier" type="xs:string" default="1" />
			836	</xs:restriction>
			837	</xs:simpleContent>
			838	</xs:complexType>
			839	</xs:element>
		-+	841	<xs:element name="days_to_radiation_treatment_end">
			842	<xs:complexType mixed="true">
			843	<xs:simpleContent>
			844	<xs:restriction base="utility:clinical_res_attributes">
			845	<xs:attribute name="cde" type="xs:string" default="" />
			846	<xs:attribute name="xsd_ver" type="xs:string" default="" />
			847	<xs:attribute name="tier" type="xs:string" default="1" />
			848	</xs:restriction>
			849	</xs:simpleContent>
			850	</xs:complexType>
			851	</xs:element>
		-+	853	<xs:element name="days_to_procedure">
			854	<xs:complexType mixed="true">
			855	<xs:simpleContent>
			856	<xs:restriction base="utility:clinical_res_attributes">
			857	<xs:attribute name="cde" type="xs:string" default="" />
			858	<xs:attribute name="xsd_ver" type="xs:string" default="" />
			859	<xs:attribute name="tier" type="xs:string" default="1" />

   
File: TCGA_BCR.OV_Clinical_FollowUp_v1.0.xsd  

1	<?xml version="1.0" encoding="utf-8" ?>	+-
4	<xs:schema elementFormDefault="qualified" version="2.5.0"	+-
5	xmlns:xs="http://www.w3.org/2001/XMLSchema"
6	xmlns:shared="http://tcga.nci/bcr/xml/clinical/shared/2.5"
7	xmlns:utility="http://tcga.nci/bcr/xml/utility/2.5"
8	xmlns:admin="http://tcga.nci/bcr/xml/administration/2.5"
9	xmlns="http://tcga.nci/bcr/xml/clinical/ov/followup/2.5/1.0"
10	targetNamespace="http://tcga.nci/bcr/xml/clinical/ov/followup/2.5/1.0"
11	xmlns:jaxb="http://java.sun.com/xml/ns/jaxb" jaxb:version="1.0" >
13	<xs:import schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/utility/2.5/TCGA_BCR.Utility.xsd" namespace="http://tcga.nci/bcr/xml/utility/2.5" />	+-
14	<xs:import schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/administration/2.5/TCGA_BCR.Administration.xsd" namespace="http://tcga.nci/bcr/xml/administration/2.5" />
15	<xs:import schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/shared/2.5/TCGA_BCR.Shared_Clinical_Elements.xsd" namespace="http://tcga.nci/bcr/xml/clinical/shared/2.5" />
17	<xs:annotation>	+-
18	<xs:appinfo>
19	<jaxb:globalBindings generateIsSetMethod="true" />
20	<jaxb:schemaBindings>
21	<jaxb:package name="nci.tcga.bcr.xml.jaxb.clinical.ov" />
22	</jaxb:schemaBindings>
23	</xs:appinfo>
24	</xs:annotation>
26	<xs:annotation>	+-
27	<xs:documentation xml:lang="en">Schema to define the elements of the TCGA Clinical Data Follow-up Form within the OV study.</xs:documentation>
28	</xs:annotation>
30	<xs:element name="follow_up_v1.0">	+-
31	<xs:complexType>
32	<xs:sequence>
33	<xs:element ref="shared:bcr_patient_barcode" />
34	<xs:element ref="shared:bcr_patient_uuid" />
35	<xs:element ref="shared:vital_status" />
36	<xs:choice>
37	<xs:sequence>
38	<xs:element ref="shared:day_of_last_followup" />
39	<xs:element ref="shared:month_of_last_followup" />
40	<xs:element ref="shared:year_of_last_followup" />
41	</xs:sequence>
42	<xs:element ref="shared:days_to_last_followup" />
43	</xs:choice>
44	<xs:choice>
45	<xs:sequence>
46	<xs:element ref="shared:day_of_death" />
47	<xs:element ref="shared:month_of_death" />
48	<xs:element ref="shared:year_of_death" />
49	</xs:sequence>
50	<xs:element ref="shared:days_to_death" />
51	</xs:choice>
52	<xs:choice>
53	<xs:sequence>
54	<xs:element ref="shared:day_of_new_tumor_event_after_initial_treatment" />
55	<xs:element ref="shared:month_of_new_tumor_event_after_initial_treatment" />
56	<xs:element ref="shared:year_of_new_tumor_event_after_initial_treatment" />
57	</xs:sequence>
58	<xs:element ref="shared:days_to_new_tumor_event_after_initial_treatment" />
59	</xs:choice>
60	<xs:element ref="shared:additional_surgery_locoregional_procedure" />
61	<xs:choice>
62	<xs:sequence>
63	<xs:element ref="shared:day_of_additional_surgery_locoregional_procedure" />
64	<xs:element ref="shared:month_of_additional_surgery_locoregional_procedure" />
65	<xs:element ref="shared:year_of_additional_surgery_locoregional_procedure" />
66	</xs:sequence>
67	<xs:element ref="shared:days_to_additional_surgery_locoregional_procedure" />
68	</xs:choice>
69	<xs:element ref="shared:person_neoplasm_cancer_status" />
70	<xs:element ref="shared:additional_pharmaceutical_therapy" />
71	<xs:element ref="shared:additional_radiation_therapy" />
72	<xs:element ref="shared:targeted_molecular_therapy" />
73	<xs:element ref="shared:radiation_therapy" />
74	<xs:element ref="shared:additional_surgery_metastatic_procedure" />
75	<xs:choice>
76	<xs:sequence>
77	<xs:element ref="shared:day_of_additional_surgery_metastatic_procedure" />
78	<xs:element ref="shared:month_of_additional_surgery_metastatic_procedure" />
79	<xs:element ref="shared:year_of_additional_surgery_metastatic_procedure" />
80	</xs:sequence>
81	<xs:element ref="shared:days_to_additional_surgery_metastatic_procedure" />
82	</xs:choice>
83	<xs:choice>
84	<xs:sequence>
85	<xs:element ref="shared:day_of_tumor_progression" />
86	<xs:element ref="shared:month_of_tumor_progression" />
87	<xs:element ref="shared:year_of_tumor_progression" />
88	</xs:sequence>
89	<xs:element ref="shared:days_to_tumor_progression" />
90	</xs:choice>
91	<xs:choice>
92	<xs:sequence>
93	<xs:element ref="shared:day_of_tumor_recurrence" />
94	<xs:element ref="shared:month_of_tumor_recurrence" />
95	<xs:element ref="shared:year_of_tumor_recurrence" />
96	</xs:sequence>
97	<xs:element ref="shared:days_to_tumor_recurrence" />
98	</xs:choice>
99	<xs:choice>
100	<xs:sequence>
101	<xs:element ref="shared:day_of_form_completion" />
102	<xs:element ref="shared:month_of_form_completion" />
103	<xs:element ref="shared:year_of_form_completion" />
104	</xs:sequence>
105	<xs:element ref="shared:days_to_form_completion" />
106	</xs:choice>
108	<xs:element ref="shared:followup_case_report_form_submission_reason" />	+-
110	<xs:element ref="shared:karnofsky_performance_score" />	+-
111	<xs:element ref="shared:eastern_cancer_oncology_group" />
112	<xs:element ref="shared:performance_status_scale_timing" />
113	<xs:element ref="shared:site_of_tumor_first_recurrence" />
114	<xs:element ref="shared:progression_determined_by" />
115	<xs:element ref="shared:progression_determined_by_notes" />
116	<xs:element ref="primary_therapy_outcome_success" />
117	</xs:sequence>
118	<xs:attribute name="version" type="xs:string" default="1.0" use="optional"/>
119	</xs:complexType>
120	</xs:element>
122	<xs:element name="primary_therapy_outcome_success" nillable="true">	+-
123	<xs:complexType>
124	<xs:simpleContent>
125	<xs:restriction base="utility:clinical_res_attributes">
126	<xs:enumeration value="" />
127	<xs:enumeration value="Progressive Disease" />
128	<xs:enumeration value="Stable Disease" />
129	<xs:enumeration value="Partial Response" />
130	<xs:enumeration value="Complete Response" />
131	<xs:attribute name="cde" type="xs:string" default="2786727" />
132	<xs:attribute name="xsd_ver" type="xs:string" default="1.11" />
133	<xs:attribute name="tier" type="xs:string" default="2" />
134	</xs:restriction>
135	</xs:simpleContent>
136	</xs:complexType>
137	</xs:element>
139	</xs:schema>	+-

   
File: TCGA_BCR.Pharmaceutical.xsd  

4	<xs:schema elementFormDefault="qualified" version="2.5.0"	<>	4	<xs:schema elementFormDefault="qualified" version="2.4.4"
6	xmlns:utility="http://tcga.nci/bcr/xml/utility/2.5"	<>	6	xmlns:utility="http://tcga.nci/bcr/xml/utility/2.4"
7	xmlns:shared="http://tcga.nci/bcr/xml/clinical/shared/2.5"		7	xmlns:shared="http://tcga.nci/bcr/xml/clinical/shared/2.4"
8	xmlns="http://tcga.nci/bcr/xml/clinical/pharmaceutical/2.5"		8	xmlns="http://tcga.nci/bcr/xml/clinical/pharmaceutical/2.4"
9	targetNamespace="http://tcga.nci/bcr/xml/clinical/pharmaceutical/2.5">		9	targetNamespace="http://tcga.nci/bcr/xml/clinical/pharmaceutical/2.4">
11	<xs:import namespace="http://tcga.nci/bcr/xml/utility/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/utility/2.5/TCGA_BCR.Utility.xsd" />	<>	11	<xs:import namespace="http://tcga.nci/bcr/xml/utility/2.4" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/utility/2.4/TCGA_BCR.Utility.xsd" />
12	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/shared/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/shared/2.5/TCGA_BCR.Shared_Clinical_Elements.xsd" />		12	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/shared/2.4" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/shared/2.4/TCGA_BCR.Shared_Clinical_Elements.xsd" />

   
File: TCGA_BCR.READ_Clinical.xsd  

4	<xs:schema elementFormDefault="qualified" version="2.5.0"	<>	4	<xs:schema elementFormDefault="qualified" version="2.4.4"
6	xmlns:utility="http://tcga.nci/bcr/xml/utility/2.5"	<>	6	xmlns:utility="http://tcga.nci/bcr/xml/utility/2.4"
7	xmlns:admin="http://tcga.nci/bcr/xml/administration/2.5"		7	xmlns:admin="http://tcga.nci/bcr/xml/administration/2.4"
8	xmlns:shared="http://tcga.nci/bcr/xml/clinical/shared/2.5"		8	xmlns:shared="http://tcga.nci/bcr/xml/clinical/shared/2.4"
9	xmlns:coad_read_shared="http://tcga.nci/bcr/xml/clinical/shared/coad_read/2.5"
10	xmlns:rad="http://tcga.nci/bcr/xml/clinical/radiation/2.5"		9	xmlns:rad="http://tcga.nci/bcr/xml/clinical/radiation/2.4"
11	xmlns:rx="http://tcga.nci/bcr/xml/clinical/pharmaceutical/2.5"		10	xmlns:rx="http://tcga.nci/bcr/xml/clinical/pharmaceutical/2.4"
12	xmlns:cqcf="http://tcga.nci/bcr/xml/clinical/cqcf/2.5"
13	xmlns:follow_up_v1.0="http://tcga.nci/bcr/xml/clinical/read/followup/2.5/1.0"
14	xmlns="http://tcga.nci/bcr/xml/clinical/read/2.5"		11	xmlns="http://tcga.nci/bcr/xml/clinical/read/2.4"
15	targetNamespace="http://tcga.nci/bcr/xml/clinical/read/2.5"		12	targetNamespace="http://tcga.nci/bcr/xml/clinical/read/2.4"
31	<xs:import namespace="http://tcga.nci/bcr/xml/utility/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/utility/2.5/TCGA_BCR.Utility.xsd" />	<>	28	<xs:import namespace="http://tcga.nci/bcr/xml/utility/2.4" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/utility/2.4/TCGA_BCR.Utility.xsd" />
32	<xs:import namespace="http://tcga.nci/bcr/xml/administration/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/administration/2.5/TCGA_BCR.Administration.xsd" />		29	<xs:import namespace="http://tcga.nci/bcr/xml/administration/2.4" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/administration/2.4/TCGA_BCR.Administration.xsd" />
33	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/shared/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/shared/2.5/TCGA_BCR.Shared_Clinical_Elements.xsd" />		30	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/shared/2.4" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/shared/2.4/TCGA_BCR.Shared_Clinical_Elements.xsd" />
34	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/radiation/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/radiation/2.5/TCGA_BCR.Radiation.xsd" />		31	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/radiation/2.4" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/radiation/2.4/TCGA_BCR.Radiation.xsd" />
35	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/pharmaceutical/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/pharmaceutical/2.5/TCGA_BCR.Pharmaceutical.xsd" />		32	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/pharmaceutical/2.4" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/pharmaceutical/2.4/TCGA_BCR.Pharmaceutical.xsd" />
36	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/cqcf/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/cqcf/2.5/TCGA_BCR.CQCF.xsd" />
37	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/read/followup/2.5/1.0" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/read/followup/2.5/TCGA_BCR.READ_Clinical_FollowUp_v1.0.xsd" />
38	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/shared/coad_read/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/shared/2.5/TCGA_BCR.Shared_Clinical_COAD_READ_Elements.xsd" />
48	<xs:attribute name="schemaVersion" type="xs:decimal" use="required" fixed="2.5"/>	<>	41	<xs:attribute name="schemaVersion" type="xs:decimal" use="required" fixed="2.4"/>
56	<xs:element ref="coad_read_shared:histological_type" />	<>	49	<xs:element ref="histological_type" />
140	<xs:element ref="shared:residual_tumor" />	+-
141	<xs:element ref="shared:anatomic_organ_subdivision" />
142	<xs:element ref="shared:primary_lymph_node_presentation_assessment" />
143	<xs:element ref="shared:lymph_node_examined_count" />
144	<xs:element ref="shared:number_of_lymphnodes_positive_by_he" />
145	<xs:element ref="shared:number_of_lymphnodes_positive_by_ihc" />
149	<xs:element ref="coad_read_shared:tumor_stage" />	<>	136	<xs:element ref="tumor_stage" />
			137	<xs:element ref="residual_tumor" />
			138	<xs:element ref="anatomic_organ_subdivision" />
			139	<xs:element ref="lymphnodes_examined" />
			140	<xs:element ref="number_of_lymphnodes_examined" />
			141	<xs:element ref="number_of_lymphnodes_positive_by_he" />
			142	<xs:element ref="number_of_lymphnodes_positive_by_ihc" />
150	<xs:element ref="coad_read_shared:primary_tumor_pathologic_spread" />		143	<xs:element ref="primary_tumor_pathologic_spread" />
151	<xs:element ref="coad_read_shared:lymphnode_pathologic_spread" />		144	<xs:element ref="lymphnode_pathologic_spread" />
152	<xs:element ref="coad_read_shared:distant_metastasis_pathologic_spread" />		145	<xs:element ref="distant_metastasis_pathologic_spread" />
153	<xs:element ref="coad_read_shared:preoperative_pretreatment_cea_level" />		146	<xs:element ref="preoperative_pretreatment_cea_level" />
154	<xs:element ref="coad_read_shared:non_nodal_tumor_deposits" />		147	<xs:element ref="non_nodal_tumor_deposits" />
155	<xs:element ref="coad_read_shared:circumferential_resection_margin" />		148	<xs:element ref="circumferential_resection_margin" />
156	<xs:element ref="shared:venous_invasion" />		149	<xs:element ref="vascular_invasion_present" />
157	<xs:element ref="shared:lymphatic_invasion" />		150	<xs:element ref="lymphatic_invasion_present" />
158	<xs:element ref="coad_read_shared:perineural_invasion_present" />		151	<xs:element ref="perineural_invasion_present" />
159	<xs:element ref="coad_read_shared:microsatellite_instability" />		152	<xs:element ref="microsatellite_instability" />
160	<xs:element ref="coad_read_shared:number_of_loci_tested" />		153	<xs:element ref="number_of_loci_tested" />
161	<xs:element ref="coad_read_shared:number_of_abnormal_loci" />		154	<xs:element ref="number_of_abnormal_loci" />
162	<xs:element ref="coad_read_shared:kras_gene_analysis_performed" />		155	<xs:element ref="kras_gene_analysis_performed" />
163	<xs:element ref="coad_read_shared:kras_mutation_found" />		156	<xs:element ref="kras_mutation_found" />
164	<xs:element ref="coad_read_shared:kras_mutation_codon" />		157	<xs:element ref="kras_mutation_codon" />
165	<xs:element ref="coad_read_shared:braf_gene_analysis_performed" />		158	<xs:element ref="braf_gene_analysis_performed" />
166	<xs:element ref="coad_read_shared:braf_gene_analysis_result" />		159	<xs:element ref="braf_gene_analysis_result" />
167	<xs:element ref="coad_read_shared:synchronous_colon_cancer_present" />		160	<xs:element ref="synchronous_colon_cancer_present" />
168	<xs:element ref="coad_read_shared:history_of_colon_polyps" />		161	<xs:element ref="history_of_colon_polyps" />
169	<xs:element ref="coad_read_shared:colon_polyps_present" />		162	<xs:element ref="colon_polyps_present" />
170	<xs:element ref="coad_read_shared:loss_expression_of_mismatch_repair_proteins_by_ihc" />		163	<xs:element ref="loss_expression_of_mismatch_repair_proteins_by_ihc" />
171	<xs:element ref="coad_read_shared:loss_expression_of_mismatch_repair_proteins_by_ihc_results" />		164	<xs:element ref="loss_expression_of_mismatch_repair_proteins_by_ihc_results" />
172	<xs:element ref="coad_read_shared:number_of_first_degree_relatives_with_cancer_diagnosis" />		165	<xs:element ref="number_of_first_degree_relatives_with_cancer_diagnosis" />
176		<>	168	</xs:sequence>
			169	</xs:complexType>
			170	</xs:element>
177	<xs:element ref="coad_read_shared:clinical_cqcf" />	<>	172	<xs:element name="lymphnodes_examined" nillable="true">
			173	<xs:complexType>
			174	<xs:simpleContent>
			175	<xs:extension base="utility:yes_or_no">
			176	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			177	<xs:attribute name="cde" type="xs:string" default="2200396" />
			178	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
			179	<xs:attribute name="tier" type="xs:string" default="1" />
			180	</xs:extension>
			181	</xs:simpleContent>
			182	</xs:complexType>
			183	</xs:element>
		<>	185	<xs:element name="number_of_abnormal_loci" nillable="true">
179	<xs:element name="follow_ups">		186	<xs:complexType mixed="true">
180	<xs:annotation>		187	<xs:simpleContent>
			188	<xs:restriction base="utility:clinical_res_attributes">
			189	<xs:attribute name="cde" type="xs:string" default="3107129" />
			190	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			191	<xs:attribute name="tier" type="xs:string" default="1" />
			192	</xs:restriction>
			193	</xs:simpleContent>
			194	</xs:complexType>
			195	</xs:element>
181	<xs:documentation>We are using namespaces and version numbers to distinguish one version of followup from another.</xs:documentation>	<>	197	<xs:element name="number_of_first_degree_relatives_with_cancer_diagnosis" nillable="true">
			198	<xs:complexType mixed="true">
			199	<xs:simpleContent>
			200	<xs:restriction base="utility:clinical_res_attributes">
			201	<xs:attribute name="cde" type="xs:string" default="3107205" />
			202	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			203	<xs:attribute name="tier" type="xs:string" default="1" />
			204	</xs:restriction>
182	</xs:annotation>		205	</xs:simpleContent>
			206	</xs:complexType>
			207	</xs:element>
		-+	209	<xs:element name="loss_expression_of_mismatch_repair_proteins_by_ihc_results">
184	<xs:sequence>	<>
185	<xs:element ref="follow_up_v1.0:follow_up_v1.0" minOccurs="0" maxOccurs="unbounded" />		211	<xs:sequence minOccurs="0" maxOccurs="unbounded">
			212	<xs:element ref="loss_expression_of_mismatch_repair_proteins_by_ihc_result" />
		<>	217	<xs:element name="loss_expression_of_mismatch_repair_proteins_by_ihc_result" nillable="true">
			218	<xs:complexType mixed="true">
			219	<xs:simpleContent>
			220	<xs:restriction base="utility:clinical_res_attributes">
			221	<xs:enumeration value="" />
			222	<xs:enumeration value="MLH1 Expressed" />
			223	<xs:enumeration value="MLH1 Not Expressed" />
			224	<xs:enumeration value="MSH2 Expressed" />
			225	<xs:enumeration value="MSH2 Not Expressed" />
			226	<xs:enumeration value="PMS2 Expressed" />
			227	<xs:enumeration value="PMS2 Not Expressed" />
			228	<xs:enumeration value="MSH6 Expressed" />
			229	<xs:enumeration value="MSH6 Not Expressed" />
			230	<xs:attribute name="cde" type="xs:string" default="3105496" />
			231	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			232	<xs:attribute name="tier" type="xs:string" default="2" />
			233	</xs:restriction>
			234	</xs:simpleContent>
			235	</xs:complexType>
190	</xs:sequence>		236	</xs:element>
		-+	238	<xs:element name="braf_gene_analysis_result" nillable="true">
			239	<xs:complexType mixed="true">
			240	<xs:simpleContent>
			241	<xs:restriction base="utility:clinical_res_attributes">
			242	<xs:enumeration value="" />
			243	<xs:enumeration value="Normal" />
			244	<xs:enumeration value="Abnormal" />
			245	<xs:attribute name="cde" type="xs:string" default="3107189" />
			246	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			247	<xs:attribute name="tier" type="xs:string" default="2" />
			248	</xs:restriction>
			249	</xs:simpleContent>
		-+	253	<xs:element name="loss_expression_of_mismatch_repair_proteins_by_ihc" nillable="true">
			254	<xs:complexType>
			255	<xs:simpleContent>
			256	<xs:extension base="utility:yes_or_no">
			257	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			258	<xs:attribute name="cde" type="xs:string" default="3123153" />
			259	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			260	<xs:attribute name="tier" type="xs:string" default="1" />
			261	</xs:extension>
			262	</xs:simpleContent>
			263	</xs:complexType>
			264	</xs:element>
		-+	266	<xs:element name="braf_gene_analysis_performed" nillable="true">
			267	<xs:complexType>
			268	<xs:simpleContent>
			269	<xs:extension base="utility:yes_or_no">
			270	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			271	<xs:attribute name="cde" type="xs:string" default="3123151" />
			272	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			273	<xs:attribute name="tier" type="xs:string" default="1" />
			274	</xs:extension>
			275	</xs:simpleContent>
			276	</xs:complexType>
			277	</xs:element>
		-+	279	<xs:element name="number_of_loci_tested" nillable="true">
			280	<xs:complexType mixed="true">
			281	<xs:simpleContent>
			282	<xs:restriction base="utility:clinical_res_attributes">
			283	<xs:attribute name="cde" type="xs:string" default="3107127" />
			284	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			285	<xs:attribute name="tier" type="xs:string" default="1" />
			286	</xs:restriction>
			287	</xs:simpleContent>
			288	</xs:complexType>
			289	</xs:element>
		-+	291	<xs:element name="kras_mutation_codon" nillable="true">
			292	<xs:complexType mixed="true">
			293	<xs:simpleContent>
			294	<xs:restriction base="utility:clinical_res_attributes">
			295	<xs:enumeration value="" />
			296	<xs:enumeration value="12" />
			297	<xs:enumeration value="13" />
			298	<xs:enumeration value="61" />
			299	<xs:attribute name="cde" type="xs:string" default="3124509" />
			300	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			301	<xs:attribute name="tier" type="xs:string" default="2" />
			302	</xs:restriction>
			303	</xs:simpleContent>
			304	</xs:complexType>
			305	</xs:element>
		-+	307	<xs:element name="kras_mutation_found" nillable="true">
			308	<xs:complexType>
			309	<xs:simpleContent>
			310	<xs:extension base="utility:yes_or_no">
			311	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			312	<xs:attribute name="cde" type="xs:string" default="2932340" />
			313	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			314	<xs:attribute name="tier" type="xs:string" default="1" />
			315	</xs:extension>
			316	</xs:simpleContent>
			317	</xs:complexType>
			318	</xs:element>
		-+	320	<xs:element name="kras_gene_analysis_performed" nillable="true">
			321	<xs:complexType>
			322	<xs:simpleContent>
			323	<xs:extension base="utility:yes_or_no">
			324	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			325	<xs:attribute name="cde" type="xs:string" default="3123147" />
			326	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			327	<xs:attribute name="tier" type="xs:string" default="1" />
			328	</xs:extension>
			329	</xs:simpleContent>
			330	</xs:complexType>
			331	</xs:element>
		-+	333	<xs:element name="number_of_lymphnodes_positive_by_he" nillable="true">
			334	<xs:complexType mixed="true">
			335	<xs:simpleContent>
			336	<xs:restriction base="utility:clinical_res_attributes">
			337	<xs:attribute name="cde" type="xs:string" default="3086388" />
			338	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
			339	<xs:attribute name="tier" type="xs:string" default="1" />
			340	</xs:restriction>
			341	</xs:simpleContent>
			342	</xs:complexType>
			343	</xs:element>
		-+	345	<xs:element name="preoperative_pretreatment_cea_level" nillable="true">
			346	<xs:complexType mixed="true">
			347	<xs:simpleContent>
			348	<xs:restriction base="utility:clinical_res_attributes">
			349	<xs:attribute name="cde" type="xs:string" default="2716510" />
			350	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
			351	<xs:attribute name="tier" type="xs:string" default="1" />
			352	</xs:restriction>
			353	</xs:simpleContent>
			354	</xs:complexType>
			355	</xs:element>
		-+	357	<xs:element name="non_nodal_tumor_deposits" nillable="true">
			358	<xs:complexType>
			359	<xs:simpleContent>
			360	<xs:extension base="utility:yes_or_no">
			361	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			362	<xs:attribute name="cde" type="xs:string" default="3107051" />
			363	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
			364	<xs:attribute name="tier" type="xs:string" default="1" />
			365	</xs:extension>
			366	</xs:simpleContent>
			367	</xs:complexType>
			368	</xs:element>
		-+	370	<xs:element name="circumferential_resection_margin" nillable="true">
			371	<xs:complexType mixed="true">
			372	<xs:simpleContent>
			373	<xs:restriction base="utility:clinical_res_attributes">
			374	<xs:attribute name="cde" type="xs:string" default="64202" />
			375	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
			376	<xs:attribute name="tier" type="xs:string" default="1" />
			377	</xs:restriction>
			378	</xs:simpleContent>
			379	</xs:complexType>
			380	</xs:element>
		-+	382	<xs:element name="vascular_invasion_present" nillable="true">
			383	<xs:complexType>
			384	<xs:simpleContent>
			385	<xs:extension base="utility:yes_or_no">
			386	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			387	<xs:attribute name="cde" type="xs:string" default="64358" />
			388	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
			389	<xs:attribute name="tier" type="xs:string" default="1" />
			390	</xs:extension>
			391	</xs:simpleContent>
			392	</xs:complexType>
			393	</xs:element>
		-+	395	<xs:element name="lymphatic_invasion_present" nillable="true">
			396	<xs:complexType>
			397	<xs:simpleContent>
			398	<xs:extension base="utility:yes_or_no">
			399	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			400	<xs:attribute name="cde" type="xs:string" default="64171" />
			401	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
			402	<xs:attribute name="tier" type="xs:string" default="1" />
			403	</xs:extension>
			404	</xs:simpleContent>
			405	</xs:complexType>
			406	</xs:element>
		-+	408	<xs:element name="perineural_invasion_present" nillable="true">
			409	<xs:complexType>
			410	<xs:simpleContent>
			411	<xs:extension base="utility:yes_or_no">
			412	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			413	<xs:attribute name="cde" type="xs:string" default="64181" />
			414	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
			415	<xs:attribute name="tier" type="xs:string" default="1" />
			416	</xs:extension>
			417	</xs:simpleContent>
			418	</xs:complexType>
			419	</xs:element>
		-+	421	<xs:element name="microsatellite_instability" nillable="true">
			422	<xs:complexType>
			423	<xs:simpleContent>
			424	<xs:extension base="utility:yes_or_no">
			425	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			426	<xs:attribute name="cde" type="xs:string" default="3123142" />
			427	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
			428	<xs:attribute name="tier" type="xs:string" default="1" />
			429	</xs:extension>
			430	</xs:simpleContent>
			431	</xs:complexType>
			432	</xs:element>
		-+	434	<xs:element name="synchronous_colon_cancer_present" nillable="true">
			435	<xs:complexType>
			436	<xs:simpleContent>
			437	<xs:extension base="utility:yes_or_no">
			438	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			439	<xs:attribute name="cde" type="xs:string" default="2185953" />
			440	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
			441	<xs:attribute name="tier" type="xs:string" default="1" />
			442	</xs:extension>
			443	</xs:simpleContent>
			444	</xs:complexType>
			445	</xs:element>
		-+	447	<xs:element name="history_of_colon_polyps" nillable="true">
			448	<xs:complexType>
			449	<xs:simpleContent>
			450	<xs:extension base="utility:yes_or_no">
			451	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			452	<xs:attribute name="cde" type="xs:string" default="3107197" />
			453	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
			454	<xs:attribute name="tier" type="xs:string" default="1" />
			455	</xs:extension>
			456	</xs:simpleContent>
			457	</xs:complexType>
			458	</xs:element>
		-+	460	<xs:element name="colon_polyps_present" nillable="true">
			461	<xs:complexType>
			462	<xs:simpleContent>
			463	<xs:extension base="utility:yes_or_no">
			464	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			465	<xs:attribute name="cde" type="xs:string" default="64184" />
			466	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
			467	<xs:attribute name="tier" type="xs:string" default="1" />
			468	</xs:extension>
			469	</xs:simpleContent>
			470	</xs:complexType>
			471	</xs:element>
		-+	474	<xs:element name="anatomic_organ_subdivision" nillable="true">
			475	<xs:complexType mixed="true">
			476	<xs:simpleContent>
			477	<xs:restriction base="utility:clinical_res_attributes">
			478	<xs:enumeration value="" />
			479	<xs:enumeration value="Sigmoid Colon" />
			480	<xs:enumeration value="Rectum" />
			481	<xs:enumeration value="Rectosigmoid Junction" />
			482	<xs:attribute name="cde" type="xs:string" default="2716417" />
			483	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
			484	<xs:attribute name="tier" type="xs:string" default="2" />
			485	</xs:restriction>
			486	</xs:simpleContent>
			487	</xs:complexType>
			488	</xs:element>
		-+	491	<xs:element name="histological_type" nillable="true">
			492	<xs:complexType mixed="true">
			493	<xs:simpleContent>
			494	<xs:restriction base="utility:clinical_res_attributes">
			495	<xs:attribute name="cde" type="xs:string" default="3081934" />
			496	<xs:attribute name="xsd_ver" type="xs:string" default="1.9" />
			497	<xs:attribute name="tier" type="xs:string" default="1" />
			498	</xs:restriction>
			499	</xs:simpleContent>
			500	</xs:complexType>
			501	</xs:element>
		-+	503	<xs:element name="tumor_stage" nillable="true">
			504	<xs:complexType>
			505	<xs:simpleContent>
			506	<xs:restriction base="utility:clinical_res_attributes">
			507	<xs:enumeration value="" />
			508	<xs:enumeration value="Stage I" />
			509	<xs:enumeration value="Stage IA" />
			510	<xs:enumeration value="Stage IB" />
			511	<xs:enumeration value="Stage II" />
			512	<xs:enumeration value="Stage IIA" />
			513	<xs:enumeration value="Stage IIB" />
			514	<xs:enumeration value="Stage IIC" />
			515	<xs:enumeration value="Stage III" />
			516	<xs:enumeration value="Stage IIIA" />
			517	<xs:enumeration value="Stage IIIB" />
			518	<xs:enumeration value="Stage IIIC" />
			519	<xs:enumeration value="Stage IV" />
			520	<xs:enumeration value="Stage IVA" />
			521	<xs:enumeration value="Stage IVB" />
			522	<xs:attribute name="cde" type="xs:string" default="3065862" />
			523	<xs:attribute name="xsd_ver" type="xs:string" default="2.4" />
			524	<xs:attribute name="tier" type="xs:string" default="1" />
			525	</xs:restriction>
			526	</xs:simpleContent>
			527	</xs:complexType>
			528	</xs:element>
		-+	530	<xs:element name="residual_tumor" nillable="true">
			531	<xs:complexType>
			532	<xs:simpleContent>
			533	<xs:restriction base="utility:clinical_res_attributes">
			534	<xs:enumeration value="" />
			535	<xs:enumeration value="RX" />
			536	<xs:enumeration value="R0" />
			537	<xs:enumeration value="R1" />
			538	<xs:enumeration value="R2" />
			539	<xs:attribute name="cde" type="xs:string" default="2608702" />
			540	<xs:attribute name="xsd_ver" type="xs:string" default="1.11" />
			541	<xs:attribute name="tier" type="xs:string" default="1" />
			542	</xs:restriction>
			543	</xs:simpleContent>
			544	</xs:complexType>
			545	</xs:element>
		-+	547	<xs:element name="primary_tumor_pathologic_spread" nillable="true">
			548	<xs:complexType>
			549	<xs:simpleContent>
			550	<xs:restriction base="utility:clinical_res_attributes">
			551	<xs:enumeration value="" />
			552	<xs:enumeration value="TX" />
			553	<xs:enumeration value="Tis" />
			554	<xs:enumeration value="T0" />
			555	<xs:enumeration value="T1" />
			556	<xs:enumeration value="T2" />
			557	<xs:enumeration value="T2a" />
			558	<xs:enumeration value="T2b" />
			559	<xs:enumeration value="T3" />
			560	<xs:enumeration value="T4" />
			561	<xs:enumeration value="T4a" />
			562	<xs:enumeration value="T4b" />
			563	<xs:attribute name="cde" type="xs:string" default="3045435" />
			564	<xs:attribute name="xsd_ver" type="xs:string" default="2.1" />
			565	<xs:attribute name="tier" type="xs:string" default="1" />
			566	</xs:restriction>
			567	</xs:simpleContent>
			568	</xs:complexType>
			569	</xs:element>
		-+	571	<xs:element name="lymphnode_pathologic_spread" nillable="true">
			572	<xs:complexType>
			573	<xs:simpleContent>
			574	<xs:restriction base="utility:clinical_res_attributes">
			575	<xs:enumeration value="" />
			576	<xs:enumeration value="NX" />
			577	<xs:enumeration value="N0" />
			578	<xs:enumeration value="N1" />
			579	<xs:enumeration value="N1a" />
			580	<xs:enumeration value="N1b" />
			581	<xs:enumeration value="N1c" />
			582	<xs:enumeration value="N2" />
			583	<xs:enumeration value="N2a" />
			584	<xs:enumeration value="N2b" />
			585	<xs:attribute name="cde" type="xs:string" default="3065858" />
			586	<xs:attribute name="xsd_ver" type="xs:string" default="2.1" />
			587	<xs:attribute name="tier" type="xs:string" default="1" />
			588	</xs:restriction>
			589	</xs:simpleContent>
			590	</xs:complexType>
			591	</xs:element>
		-+	593	<xs:element name="distant_metastasis_pathologic_spread" nillable="true">
			594	<xs:complexType>
			595	<xs:simpleContent>
			596	<xs:restriction base="utility:clinical_res_attributes">
			597	<xs:enumeration value="" />
			598	<xs:enumeration value="M0" />
			599	<xs:enumeration value="M1" />
			600	<xs:enumeration value="M1a" />
			601	<xs:enumeration value="M1b" />
			602	<xs:enumeration value="MX" />
			603	<xs:attribute name="cde" type="xs:string" default="3045439" />
			604	<xs:attribute name="xsd_ver" type="xs:string" default="2.4" />
			605	<xs:attribute name="tier" type="xs:string" default="1" />
			606	</xs:restriction>
			607	</xs:simpleContent>
			608	</xs:complexType>
			609	</xs:element>
		-+	611	<xs:element name="number_of_lymphnodes_examined" nillable="true">
			612	<xs:complexType mixed="true">
			613	<xs:simpleContent>
			614	<xs:restriction base="utility:clinical_res_attributes">
			615	<xs:attribute name="cde" type="xs:string" default="3" />
			616	<xs:attribute name="xsd_ver" type="xs:string" default="2.1" />
			617	<xs:attribute name="tier" type="xs:string" default="1" />
			618	</xs:restriction>
			619	</xs:simpleContent>
			620	</xs:complexType>
			621	</xs:element>
		-+	623	<xs:element name="number_of_lymphnodes_positive_by_ihc" nillable="true">
			624	<xs:complexType mixed="true">
			625	<xs:simpleContent>
			626	<xs:restriction base="utility:clinical_res_attributes">
			627	<xs:attribute name="cde" type="xs:string" default="3086383" />
			628	<xs:attribute name="xsd_ver" type="xs:string" default="2.1" />
			629	<xs:attribute name="tier" type="xs:string" default="1" />
			630	</xs:restriction>
			631	</xs:simpleContent>
			632	</xs:complexType>
			633	</xs:element>

   
File: TCGA_BCR.READ_Clinical_FollowUp_v1.0.xsd  

1	<?xml version="1.0" encoding="utf-8" ?>	+-
4	<xs:schema elementFormDefault="qualified" version="2.5.0"	+-
5	xmlns:xs="http://www.w3.org/2001/XMLSchema"
6	xmlns:shared="http://tcga.nci/bcr/xml/clinical/shared/2.5"
7	xmlns:utility="http://tcga.nci/bcr/xml/utility/2.5"
8	xmlns:admin="http://tcga.nci/bcr/xml/administration/2.5"
9	xmlns="http://tcga.nci/bcr/xml/clinical/read/followup/2.5/1.0"
10	targetNamespace="http://tcga.nci/bcr/xml/clinical/read/followup/2.5/1.0"
11	xmlns:jaxb="http://java.sun.com/xml/ns/jaxb" jaxb:version="1.0" >
13	<xs:import schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/utility/2.5/TCGA_BCR.Utility.xsd" namespace="http://tcga.nci/bcr/xml/utility/2.5" />	+-
14	<xs:import schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/administration/2.5/TCGA_BCR.Administration.xsd" namespace="http://tcga.nci/bcr/xml/administration/2.5" />
15	<xs:import schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/shared/2.5/TCGA_BCR.Shared_Clinical_Elements.xsd" namespace="http://tcga.nci/bcr/xml/clinical/shared/2.5" />
17	<xs:annotation>	+-
18	<xs:appinfo>
19	<jaxb:globalBindings generateIsSetMethod="true" />
20	<jaxb:schemaBindings>
21	<jaxb:package name="nci.tcga.bcr.xml.jaxb.clinical.read" />
22	</jaxb:schemaBindings>
23	</xs:appinfo>
24	</xs:annotation>
26	<xs:annotation>	+-
27	<xs:documentation xml:lang="en">Schema to define the elements of the TCGA Clinical Data Follow-up Form within the READ study.</xs:documentation>
28	</xs:annotation>
30	<xs:element name="follow_up_v1.0">	+-
31	<xs:complexType>
32	<xs:sequence>
33	<xs:element ref="shared:bcr_patient_barcode" />
34	<xs:element ref="shared:bcr_patient_uuid" />
35	<xs:element ref="shared:vital_status" />
36	<xs:choice>
37	<xs:sequence>
38	<xs:element ref="shared:day_of_last_followup" />
39	<xs:element ref="shared:month_of_last_followup" />
40	<xs:element ref="shared:year_of_last_followup" />
41	</xs:sequence>
42	<xs:element ref="shared:days_to_last_followup" />
43	</xs:choice>
44	<xs:choice>
45	<xs:sequence>
46	<xs:element ref="shared:day_of_death" />
47	<xs:element ref="shared:month_of_death" />
48	<xs:element ref="shared:year_of_death" />
49	</xs:sequence>
50	<xs:element ref="shared:days_to_death" />
51	</xs:choice>
52	<xs:element ref="shared:new_tumor_event_after_initial_treatment" />
53	<xs:choice>
54	<xs:sequence>
55	<xs:element ref="shared:day_of_new_tumor_event_after_initial_treatment" />
56	<xs:element ref="shared:month_of_new_tumor_event_after_initial_treatment" />
57	<xs:element ref="shared:year_of_new_tumor_event_after_initial_treatment" />
58	</xs:sequence>
59	<xs:element ref="shared:days_to_new_tumor_event_after_initial_treatment" />
60	</xs:choice>
61	<xs:element ref="shared:additional_surgery_locoregional_procedure" />
62	<xs:choice>
63	<xs:sequence>
64	<xs:element ref="shared:day_of_additional_surgery_locoregional_procedure" />
65	<xs:element ref="shared:month_of_additional_surgery_locoregional_procedure" />
66	<xs:element ref="shared:year_of_additional_surgery_locoregional_procedure" />
67	</xs:sequence>
68	<xs:element ref="shared:days_to_additional_surgery_locoregional_procedure" />
69	</xs:choice>
70	<xs:element ref="shared:person_neoplasm_cancer_status" />
71	<xs:element ref="shared:radiation_therapy" />
72	<xs:element ref="shared:additional_radiation_therapy" />
73	<xs:element ref="shared:targeted_molecular_therapy" />
74	<xs:element ref="shared:additional_pharmaceutical_therapy" />
75	<xs:element ref="shared:additional_surgery_metastatic_procedure" />
76	<xs:choice>
77	<xs:sequence>
78	<xs:element ref="shared:day_of_additional_surgery_metastatic_procedure" />
79	<xs:element ref="shared:month_of_additional_surgery_metastatic_procedure" />
80	<xs:element ref="shared:year_of_additional_surgery_metastatic_procedure" />
81	</xs:sequence>
82	<xs:element ref="shared:days_to_additional_surgery_metastatic_procedure" />
83	</xs:choice>
84	<xs:choice>
85	<xs:sequence>
86	<xs:element ref="shared:day_of_form_completion" />
87	<xs:element ref="shared:month_of_form_completion" />
88	<xs:element ref="shared:year_of_form_completion" />
89	</xs:sequence>
90	<xs:element ref="shared:days_to_form_completion" />
91	</xs:choice>
93	<xs:element ref="shared:followup_case_report_form_submission_reason" />	+-
95	<xs:element ref="shared:residual_disease_post_new_tumor_event_margin_status" />	+-
96	<xs:element ref="site_of_additional_surgery_new_tumor_event_mets" />
97	</xs:sequence>
98	<xs:attribute name="version" type="xs:string" default="1.0" use="optional"/>
99	</xs:complexType>
100	</xs:element>
102	<xs:element name="site_of_additional_surgery_new_tumor_event_mets">	+-
103	<xs:complexType>
104	<xs:simpleContent>
105	<xs:restriction base="utility:clinical_res_attributes">
106	<xs:enumeration value="" />
107	<xs:enumeration value="Liver" />
108	<xs:enumeration value="Lung" />
109	<xs:enumeration value="Lymph Nodes" />
110	<xs:enumeration value="Other" />
111	<xs:attribute name="cde" type="xs:string" default="1611" />
112	<xs:attribute name="xsd_ver" type="xs:string" default="2.5" />
113	<xs:attribute name="tier" type="xs:string" default="2" />
114	</xs:restriction>
115	</xs:simpleContent>
116	</xs:complexType>
117	</xs:element>
120	</xs:schema>	+-

   
File: TCGA_BCR.Shared_Clinical_COAD_READ_Elements.xsd  

1	<?xml version="1.0" encoding="utf-8"?>	+-
3	<xs:schema xmlns:xs="http://www.w3.org/2001/XMLSchema" xmlns:utility="http://tcga.nci/bcr/xml/utility/2.5" xmlns:shared="http://tcga.nci/bcr/xml/clinical/shared/2.5" xmlns:cqcf="http://tcga.nci/bcr/xml/clinical/cqcf/2.5" xmlns="http://tcga.nci/bcr/xml/clinical/shared/coad_read/2.5" targetNamespace="http://tcga.nci/bcr/xml/clinical/shared/coad_read/2.5" elementFormDefault="qualified" version="2.5.0">	+-
4	<xs:import namespace="http://tcga.nci/bcr/xml/utility/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/utility/2.5/TCGA_BCR.Utility.xsd"/>
5	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/shared/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/shared/2.5/TCGA_BCR.Shared_Clinical_Elements.xsd"/>
6	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/cqcf/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/cqcf/2.5/TCGA_BCR.CQCF.xsd"/>
7	<xs:element name="number_of_abnormal_loci" nillable="true">
8	<xs:complexType mixed="true">
9	<xs:simpleContent>
10	<xs:restriction base="utility:clinical_res_attributes">
11	<xs:attribute name="cde" type="xs:string" default="3107129"/>
12	<xs:attribute name="xsd_ver" type="xs:string" default="2.3"/>
13	<xs:attribute name="tier" type="xs:string" default="1"/>
14	</xs:restriction>
15	</xs:simpleContent>
16	</xs:complexType>
17	</xs:element>
18	<xs:element name="number_of_first_degree_relatives_with_cancer_diagnosis" nillable="true">
19	<xs:complexType mixed="true">
20	<xs:simpleContent>
21	<xs:restriction base="utility:clinical_res_attributes">
22	<xs:attribute name="cde" type="xs:string" default="3107205"/>
23	<xs:attribute name="xsd_ver" type="xs:string" default="2.3"/>
24	<xs:attribute name="tier" type="xs:string" default="1"/>
25	</xs:restriction>
26	</xs:simpleContent>
27	</xs:complexType>
28	</xs:element>
29	<xs:element name="loss_expression_of_mismatch_repair_proteins_by_ihc_results">
30	<xs:complexType>
31	<xs:sequence minOccurs="0" maxOccurs="unbounded">
32	<xs:element ref="loss_expression_of_mismatch_repair_proteins_by_ihc_result"/>
33	</xs:sequence>
34	</xs:complexType>
35	</xs:element>
36	<xs:element name="loss_expression_of_mismatch_repair_proteins_by_ihc_result" nillable="true">
37	<xs:complexType mixed="true">
38	<xs:simpleContent>
39	<xs:restriction base="utility:clinical_res_attributes">
40	<xs:enumeration value=""/>
41	<xs:enumeration value="MLH1 Expressed"/>
42	<xs:enumeration value="MLH1 Not Expressed"/>
43	<xs:enumeration value="MSH2 Expressed"/>
44	<xs:enumeration value="MSH2 Not Expressed"/>
45	<xs:enumeration value="PMS2 Expressed"/>
46	<xs:enumeration value="PMS2 Not Expressed"/>
47	<xs:enumeration value="MSH6 Expressed"/>
48	<xs:enumeration value="MSH6 Not Expressed"/>
49	<xs:attribute name="cde" type="xs:string" default="3105496"/>
50	<xs:attribute name="xsd_ver" type="xs:string" default="2.3"/>
51	<xs:attribute name="tier" type="xs:string" default="2"/>
52	</xs:restriction>
53	</xs:simpleContent>
54	</xs:complexType>
55	</xs:element>
56	<xs:element name="braf_gene_analysis_result" nillable="true">
57	<xs:complexType mixed="true">
58	<xs:simpleContent>
59	<xs:restriction base="utility:clinical_res_attributes">
60	<xs:enumeration value=""/>
61	<xs:enumeration value="Normal"/>
62	<xs:enumeration value="Abnormal"/>
63	<xs:attribute name="cde" type="xs:string" default="3107189"/>
64	<xs:attribute name="xsd_ver" type="xs:string" default="2.3"/>
65	<xs:attribute name="tier" type="xs:string" default="2"/>
66	</xs:restriction>
67	</xs:simpleContent>
68	</xs:complexType>
69	</xs:element>
70	<xs:element name="loss_expression_of_mismatch_repair_proteins_by_ihc" nillable="true">
71	<xs:complexType>
72	<xs:simpleContent>
73	<xs:extension base="utility:yes_or_no">
74	<xs:attributeGroup ref="utility:common_ext_attribute_group"/>
75	<xs:attribute name="cde" type="xs:string" default="3123153"/>
76	<xs:attribute name="xsd_ver" type="xs:string" default="2.3"/>
77	<xs:attribute name="tier" type="xs:string" default="1"/>
78	</xs:extension>
79	</xs:simpleContent>
80	</xs:complexType>
81	</xs:element>
82	<xs:element name="braf_gene_analysis_performed" nillable="true">
83	<xs:complexType>
84	<xs:simpleContent>
85	<xs:extension base="utility:yes_or_no">
86	<xs:attributeGroup ref="utility:common_ext_attribute_group"/>
87	<xs:attribute name="cde" type="xs:string" default="3123151"/>
88	<xs:attribute name="xsd_ver" type="xs:string" default="2.3"/>
89	<xs:attribute name="tier" type="xs:string" default="1"/>
90	</xs:extension>
91	</xs:simpleContent>
92	</xs:complexType>
93	</xs:element>
94	<xs:element name="number_of_loci_tested" nillable="true">
95	<xs:complexType mixed="true">
96	<xs:simpleContent>
97	<xs:restriction base="utility:clinical_res_attributes">
98	<xs:attribute name="cde" type="xs:string" default="3107127"/>
99	<xs:attribute name="xsd_ver" type="xs:string" default="2.3"/>
100	<xs:attribute name="tier" type="xs:string" default="1"/>
101	</xs:restriction>
102	</xs:simpleContent>
103	</xs:complexType>
104	</xs:element>
105	<xs:element name="kras_mutation_codon" nillable="true">
106	<xs:complexType mixed="true">
107	<xs:simpleContent>
108	<xs:restriction base="utility:clinical_res_attributes">
109	<xs:enumeration value=""/>
110	<xs:enumeration value="12"/>
111	<xs:enumeration value="13"/>
112	<xs:enumeration value="61"/>
113	<xs:attribute name="cde" type="xs:string" default="3124509"/>
114	<xs:attribute name="xsd_ver" type="xs:string" default="2.3"/>
115	<xs:attribute name="tier" type="xs:string" default="2"/>
116	</xs:restriction>
117	</xs:simpleContent>
118	</xs:complexType>
119	</xs:element>
120	<xs:element name="kras_mutation_found" nillable="true">
121	<xs:complexType>
122	<xs:simpleContent>
123	<xs:extension base="utility:yes_or_no">
124	<xs:attributeGroup ref="utility:common_ext_attribute_group"/>
125	<xs:attribute name="cde" type="xs:string" default="2932340"/>
126	<xs:attribute name="xsd_ver" type="xs:string" default="2.3"/>
127	<xs:attribute name="tier" type="xs:string" default="1"/>
128	</xs:extension>
129	</xs:simpleContent>
130	</xs:complexType>
131	</xs:element>
132	<xs:element name="kras_gene_analysis_performed" nillable="true">
133	<xs:complexType>
134	<xs:simpleContent>
135	<xs:extension base="utility:yes_or_no">
136	<xs:attributeGroup ref="utility:common_ext_attribute_group"/>
137	<xs:attribute name="cde" type="xs:string" default="3123147"/>
138	<xs:attribute name="xsd_ver" type="xs:string" default="2.3"/>
139	<xs:attribute name="tier" type="xs:string" default="1"/>
140	</xs:extension>
141	</xs:simpleContent>
142	</xs:complexType>
143	</xs:element>
144	<xs:element name="preoperative_pretreatment_cea_level" nillable="true">
145	<xs:complexType mixed="true">
146	<xs:simpleContent>
147	<xs:restriction base="utility:clinical_res_attributes">
148	<xs:attribute name="cde" type="xs:string" default="2716510"/>
149	<xs:attribute name="xsd_ver" type="xs:string" default="2.2"/>
150	<xs:attribute name="tier" type="xs:string" default="1"/>
151	</xs:restriction>
152	</xs:simpleContent>
153	</xs:complexType>
154	</xs:element>
155	<xs:element name="non_nodal_tumor_deposits" nillable="true">
156	<xs:complexType>
157	<xs:simpleContent>
158	<xs:extension base="utility:yes_or_no">
159	<xs:attributeGroup ref="utility:common_ext_attribute_group"/>
160	<xs:attribute name="cde" type="xs:string" default="3107051"/>
161	<xs:attribute name="xsd_ver" type="xs:string" default="2.2"/>
162	<xs:attribute name="tier" type="xs:string" default="1"/>
163	</xs:extension>
164	</xs:simpleContent>
165	</xs:complexType>
166	</xs:element>
167	<xs:element name="circumferential_resection_margin" nillable="true">
168	<xs:complexType mixed="true">
169	<xs:simpleContent>
170	<xs:restriction base="utility:clinical_res_attributes">
171	<xs:attribute name="cde" type="xs:string" default="64202"/>
172	<xs:attribute name="xsd_ver" type="xs:string" default="2.2"/>
173	<xs:attribute name="tier" type="xs:string" default="1"/>
174	</xs:restriction>
175	</xs:simpleContent>
176	</xs:complexType>
177	</xs:element>
178	<xs:element name="perineural_invasion_present" nillable="true">
179	<xs:complexType>
180	<xs:simpleContent>
181	<xs:extension base="utility:yes_or_no">
182	<xs:attributeGroup ref="utility:common_ext_attribute_group"/>
183	<xs:attribute name="cde" type="xs:string" default="64181"/>
184	<xs:attribute name="xsd_ver" type="xs:string" default="2.2"/>
185	<xs:attribute name="tier" type="xs:string" default="1"/>
186	</xs:extension>
187	</xs:simpleContent>
188	</xs:complexType>
189	</xs:element>
190	<xs:element name="microsatellite_instability" nillable="true">
191	<xs:complexType>
192	<xs:simpleContent>
193	<xs:extension base="utility:yes_or_no">
194	<xs:attributeGroup ref="utility:common_ext_attribute_group"/>
195	<xs:attribute name="cde" type="xs:string" default="3123142"/>
196	<xs:attribute name="xsd_ver" type="xs:string" default="2.2"/>
197	<xs:attribute name="tier" type="xs:string" default="1"/>
198	</xs:extension>
199	</xs:simpleContent>
200	</xs:complexType>
201	</xs:element>
202	<xs:element name="synchronous_colon_cancer_present" nillable="true">
203	<xs:complexType>
204	<xs:simpleContent>
205	<xs:extension base="utility:yes_or_no">
206	<xs:attributeGroup ref="utility:common_ext_attribute_group"/>
207	<xs:attribute name="cde" type="xs:string" default="2185953"/>
208	<xs:attribute name="xsd_ver" type="xs:string" default="2.2"/>
209	<xs:attribute name="tier" type="xs:string" default="1"/>
210	</xs:extension>
211	</xs:simpleContent>
212	</xs:complexType>
213	</xs:element>
214	<xs:element name="history_of_colon_polyps" nillable="true">
215	<xs:complexType>
216	<xs:simpleContent>
217	<xs:extension base="utility:yes_or_no">
218	<xs:attributeGroup ref="utility:common_ext_attribute_group"/>
219	<xs:attribute name="cde" type="xs:string" default="3107197"/>
220	<xs:attribute name="xsd_ver" type="xs:string" default="2.2"/>
221	<xs:attribute name="tier" type="xs:string" default="1"/>
222	</xs:extension>
223	</xs:simpleContent>
224	</xs:complexType>
225	</xs:element>
226	<xs:element name="colon_polyps_present" nillable="true">
227	<xs:complexType>
228	<xs:simpleContent>
229	<xs:extension base="utility:yes_or_no">
230	<xs:attributeGroup ref="utility:common_ext_attribute_group"/>
231	<xs:attribute name="cde" type="xs:string" default="64184"/>
232	<xs:attribute name="xsd_ver" type="xs:string" default="2.2"/>
233	<xs:attribute name="tier" type="xs:string" default="1"/>
234	</xs:extension>
235	</xs:simpleContent>
236	</xs:complexType>
237	</xs:element>
238	<xs:element name="histological_type" nillable="true">
239	<xs:complexType mixed="true">
240	<xs:simpleContent>
241	<xs:restriction base="utility:clinical_res_attributes">
242	<xs:attribute name="cde" type="xs:string" default="3081934"/>
243	<xs:attribute name="xsd_ver" type="xs:string" default="1.9"/>
244	<xs:attribute name="tier" type="xs:string" default="1"/>
245	</xs:restriction>
246	</xs:simpleContent>
247	</xs:complexType>
248	</xs:element>
249	<xs:element name="tumor_stage" nillable="true">
250	<xs:complexType>
251	<xs:simpleContent>
252	<xs:restriction base="utility:clinical_res_attributes">
253	<xs:enumeration value=""/>
254	<xs:enumeration value="Stage I"/>
255	<xs:enumeration value="Stage IA"/>
256	<xs:enumeration value="Stage IB"/>
257	<xs:enumeration value="Stage II"/>
258	<xs:enumeration value="Stage IIA"/>
259	<xs:enumeration value="Stage IIB"/>
260	<xs:enumeration value="Stage IIC"/>
261	<xs:enumeration value="Stage III"/>
262	<xs:enumeration value="Stage IIIA"/>
263	<xs:enumeration value="Stage IIIB"/>
264	<xs:enumeration value="Stage IIIC"/>
265	<xs:enumeration value="Stage IV"/>
266	<xs:enumeration value="Stage IVA"/>
267	<xs:enumeration value="Stage IVB"/>
268	<xs:attribute name="cde" type="xs:string" default="3065862"/>
269	<xs:attribute name="xsd_ver" type="xs:string" default="2.4"/>
270	<xs:attribute name="tier" type="xs:string" default="1"/>
271	</xs:restriction>
272	</xs:simpleContent>
273	</xs:complexType>
274	</xs:element>
275	<xs:element name="primary_tumor_pathologic_spread" nillable="true">
276	<xs:complexType>
277	<xs:simpleContent>
278	<xs:restriction base="utility:clinical_res_attributes">
279	<xs:enumeration value=""/>
280	<xs:enumeration value="TX"/>
281	<xs:enumeration value="Tis"/>
282	<xs:enumeration value="T0"/>
283	<xs:enumeration value="T1"/>
284	<xs:enumeration value="T2"/>
285	<xs:enumeration value="T3"/>
286	<xs:enumeration value="T4a"/>
287	<xs:enumeration value="T4b"/>
288	<xs:attribute name="cde" type="xs:string" default="3045435"/>
289	<xs:attribute name="xsd_ver" type="xs:string" default="2.1"/>
290	<xs:attribute name="tier" type="xs:string" default="1"/>
291	</xs:restriction>
292	</xs:simpleContent>
293	</xs:complexType>
294	</xs:element>
295	<xs:element name="lymphnode_pathologic_spread" nillable="true">
296	<xs:complexType>
297	<xs:simpleContent>
298	<xs:restriction base="utility:clinical_res_attributes">
299	<xs:enumeration value=""/>
300	<xs:enumeration value="NX"/>
301	<xs:enumeration value="N0"/>
302	<xs:enumeration value="N1"/>
303	<xs:enumeration value="N1a"/>
304	<xs:enumeration value="N1b"/>
305	<xs:enumeration value="N1c"/>
306	<xs:enumeration value="N2"/>
307	<xs:enumeration value="N2a"/>
308	<xs:enumeration value="N2b"/>
309	<xs:enumeration value="N3"/>
310	<xs:attribute name="cde" type="xs:string" default="3065858"/>
311	<xs:attribute name="xsd_ver" type="xs:string" default="2.1"/>
312	<xs:attribute name="tier" type="xs:string" default="1"/>
313	</xs:restriction>
314	</xs:simpleContent>
315	</xs:complexType>
316	</xs:element>
317	<xs:element name="distant_metastasis_pathologic_spread" nillable="true">
318	<xs:complexType>
319	<xs:simpleContent>
320	<xs:restriction base="utility:clinical_res_attributes">
321	<xs:enumeration value=""/>
322	<xs:enumeration value="M0"/>
323	<xs:enumeration value="M1"/>
324	<xs:enumeration value="M1a"/>
325	<xs:enumeration value="M1b"/>
326	<xs:enumeration value="MX"/>
327	<xs:attribute name="cde" type="xs:string" default="3045439"/>
328	<xs:attribute name="xsd_ver" type="xs:string" default="2.4"/>
329	<xs:attribute name="tier" type="xs:string" default="1"/>
330	</xs:restriction>
331	</xs:simpleContent>
332	</xs:complexType>
333	</xs:element>
334	<xs:element name="clinical_cqcf">
335	<xs:complexType>
336	<xs:sequence>
337	<xs:element ref="cqcf:frozen_specimen_anatomic_site"/>
338	<xs:element ref="cqcf:history_of_prior_malignancy"/>
339	<xs:element ref="cqcf:history_of_neoadjuvant_treatment"/>
340	<xs:element ref="cqcf:consent_or_death_status"/>
341	<xs:choice>
342	<xs:choice>
343	<xs:sequence>
344	<xs:element ref="cqcf:day_of_consent"/>
345	<xs:element ref="cqcf:month_of_consent"/>
346	<xs:element ref="cqcf:year_of_consent"/>
347	</xs:sequence>
348	<xs:element ref="cqcf:days_to_consent"/>
349	</xs:choice>
350	<xs:choice>
351	<xs:sequence>
352	<xs:element ref="shared:day_of_death"/>
353	<xs:element ref="shared:month_of_death"/>
354	<xs:element ref="shared:year_of_death"/>
355	</xs:sequence>
356	<xs:element ref="shared:days_to_death"/>
357	</xs:choice>
358	</xs:choice>
359	<xs:element ref="cqcf:diagnosis_subtype"/>
360	<xs:element ref="shared:prior_diagnosis"/>
361	<xs:element ref="cqcf:normal_tissue_anatomic_site"/>
362	<xs:element ref="cqcf:normal_tissue_proximity"/>
363	<xs:element ref="cqcf:tumor_type"/>
364	<xs:element ref="cqcf:histological_subtype" minOccurs="0"/>
365	<xs:element ref="cqcf:other_anatomic_site" minOccurs="0"/>
366	<xs:element ref="cqcf:country"/>
367	</xs:sequence>
368	</xs:complexType>
369	</xs:element>
370	</xs:schema>

   
File: TCGA_BCR.Shared_Clinical_Elements.xsd  

4	<xs:schema elementFormDefault="qualified" version="2.5.0"	<>	4	<xs:schema elementFormDefault="qualified" version="2.4.4"
6	xmlns:utility="http://tcga.nci/bcr/xml/utility/2.5"	<>	6	xmlns:utility="http://tcga.nci/bcr/xml/utility/2.4"
7	xmlns="http://tcga.nci/bcr/xml/clinical/shared/2.5"		7	xmlns="http://tcga.nci/bcr/xml/clinical/shared/2.4"
8	targetNamespace="http://tcga.nci/bcr/xml/clinical/shared/2.5">		8	targetNamespace="http://tcga.nci/bcr/xml/clinical/shared/2.4">
10	<xs:import namespace="http://tcga.nci/bcr/xml/utility/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/utility/2.5/TCGA_BCR.Utility.xsd" />	<>	10	<xs:import namespace="http://tcga.nci/bcr/xml/utility/2.4" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/utility/2.4/TCGA_BCR.Utility.xsd" />
347	<xs:enumeration value="Prostate" />	+-
351	<xs:enumeration value="Skin" />	+-
352	<xs:enumeration value="Subcutaneous tissue" />
353	<xs:enumeration value="Lymph node(s) Regional" />
354	<xs:enumeration value="Lymph node(s) Distant" />
525	<xs:enumeration value="Loco-Regional" />	<>	521	<xs:enumeration value="LOCO-REGIONAL" />
526	<xs:enumeration value="Metastasis" />		522	<xs:enumeration value="METASTASIS" />
527	<xs:enumeration value="Locoregional and Metastasis" />
859	<xs:enumeration value="Aspirate" />	<>	854	<xs:enumeration value="CYTOLOGY" />
			855	<xs:enumeration value="FINE NEEDLE ASPIRATION BIOPSY" />
			856	<xs:enumeration value="INCISION BIOPSY" />
			857	<xs:enumeration value="EXCISIONAL BIOPSY" />
			858	<xs:enumeration value="TUMOR RESECTION" />
			859	<xs:enumeration value="OTHER METHOD, SPECIFY IN NOTES" />
		<>	862	<xs:enumeration value="Endoscopic Biopsy" />
860	<xs:enumeration value="Biopsy (cervical / CT-guided / Other)" />		863	<xs:enumeration value="Transurethral resection (TURBT)" />
862	<xs:enumeration value="Core needle biopsy" />	<>	865	<xs:enumeration value="Lymph node sampling or dissection" />
863	<xs:enumeration value="Cytology (e.g. Peritoneal or pleural fluid)" />
864	<xs:enumeration value="Dilation and curettage procedure" />		866	<xs:enumeration value="Tumor resection" />
865	<xs:enumeration value="Endoscopic Biopsy" />		867	<xs:enumeration value="Incisional Biopsy" />
		-+	869	<xs:enumeration value="Unknown" />
			870	<xs:enumeration value="Cytology (e.g. Peritoneal or pleural fluid)" />
868	<xs:enumeration value="Incisional Biopsy" />	<>
869	<xs:enumeration value="Lymph node sampling or dissection" />		872	<xs:enumeration value="Dilation and curettage procedure" />
871	<xs:enumeration value="Other method, specify:" />	<>	874	<xs:enumeration value="Aspirate" />
872	<xs:enumeration value="Transurethral resection (TURBT)" />		875	<xs:enumeration value="Core needle biopsy" />
873	<xs:enumeration value="Tumor resection" />		876	<xs:enumeration value="Biopsy (cervical / CT-guided / Other)" />
874	<xs:enumeration value="Unknown" />
876	<xs:attribute name="xsd_ver" type="xs:string" default="2.5" />	<>	878	<xs:attribute name="xsd_ver" type="xs:string" default="1.9" />
		-+	1162	<xs:enumeration value="AT RECURRENCE/PROGRESSION OF DISEASE" />
			1163	<xs:enumeration value="PREOPERATIVE" />
			1164	<xs:enumeration value="PRE-ADJUVANT THERAPY" />
			1165	<xs:enumeration value="POST-ADJUVANT THERAPY" />
			1166	<xs:enumeration value="POST-SECONDARY THERAPY" />
			1167	<xs:enumeration value="OTHER" />
1199	<xs:enumeration value="Laboratory" />	<>	1208	<xs:enumeration value="LABORATORY" />
1200	<xs:enumeration value="Pathology" />		1209	<xs:enumeration value="PATHOLOGY" />
1201	<xs:enumeration value="Radiation" />		1210	<xs:enumeration value="RADIATION" />
1202	<xs:enumeration value="Physical Examination" />		1211	<xs:enumeration value="PHYSICAL EXAMINATION" />
1203	<xs:enumeration value="Imaging Study" />		1212	<xs:enumeration value="IMAGING STUDY" />
1204	<xs:enumeration value="Molecular Marker(S)" />		1213	<xs:enumeration value="MOLECULAR MARKER(S)" />
1205	<xs:enumeration value="First Seen At Further Surgery" />		1214	<xs:enumeration value="FIRST SEEN AT FURTHER SURGERY" />
1206	<xs:enumeration value="Biopsy with Histologic Confirmation" />
1207	<xs:enumeration value="Convincing Imaging" />
1208	<xs:enumeration value="Positive Biomarker (s)" />
1209	<xs:enumeration value="Other Method: Specify In Notes" />		1215	<xs:enumeration value="OTHER METHOD: SPECIFY IN NOTES" />
1557	<xs:element name="ajcc_tumor_stage_code" nillable="true">	+-
1558	<xs:complexType mixed="true">
1559	<xs:simpleContent>
1560	<xs:restriction base="utility:clinical_res_attributes">
1561	<xs:enumeration value="" />
1562	<xs:enumeration value="T0" />
1563	<xs:enumeration value="Ta" />
1564	<xs:enumeration value="T1" />
1565	<xs:enumeration value="T1a" />
1566	<xs:enumeration value="T1a1" />
1567	<xs:enumeration value="T1a2" />
1568	<xs:enumeration value="T1b" />
1569	<xs:enumeration value="T1b1" />
1570	<xs:enumeration value="T1b2" />
1571	<xs:enumeration value="T1c" />
1572	<xs:enumeration value="T1mi" />
1573	<xs:enumeration value="T2" />
1574	<xs:enumeration value="T2a" />
1575	<xs:enumeration value="T2a1" />
1576	<xs:enumeration value="T2a2" />
1577	<xs:enumeration value="T2b" />
1578	<xs:enumeration value="T2c" />
1579	<xs:enumeration value="T3" />
1580	<xs:enumeration value="T3a" />
1581	<xs:enumeration value="T3b" />
1582	<xs:enumeration value="T3c" />
1583	<xs:enumeration value="T4" />
1584	<xs:enumeration value="T4a" />
1585	<xs:enumeration value="T4b" />
1586	<xs:enumeration value="T4c" />
1587	<xs:enumeration value="T4d" />
1588	<xs:enumeration value="Tis" />
1589	<xs:enumeration value="Tis (DCIS)" />
1590	<xs:enumeration value="Tis (LCIS)" />
1591	<xs:enumeration value="Tis (Paget's)" />
1592	<xs:enumeration value="TX" />
1593	<xs:attribute name="cde" type="xs:string" default="3045435" />
1594	<xs:attribute name="xsd_ver" type="xs:string" default="2.5" />
1595	<xs:attribute name="tier" type="xs:string" default="1" />
1596	</xs:restriction>
1597	</xs:simpleContent>
1598	</xs:complexType>
1599	</xs:element>
1601	<xs:element name="ajcc_neoplasm_disease_lymph_node_stage" nillable="true">	+-
1602	<xs:complexType mixed="true">
1603	<xs:simpleContent>
1604	<xs:restriction base="utility:clinical_res_attributes">
1605	<xs:enumeration value="" />
1606	<xs:enumeration value="NX" />
1607	<xs:enumeration value="N0" />
1608	<xs:enumeration value="N0 (i-)" />
1609	<xs:enumeration value="N0 (i+)" />
1610	<xs:enumeration value="N0 (mol-)" />
1611	<xs:enumeration value="N0 (mol+)" />
1612	<xs:enumeration value="N1" />
1613	<xs:enumeration value="N1mi" />
1614	<xs:enumeration value="N1a" />
1615	<xs:enumeration value="N1b" />
1616	<xs:enumeration value="N1bI" />
1617	<xs:enumeration value="N1bII" />
1618	<xs:enumeration value="N1bIII" />
1619	<xs:enumeration value="N1bIV" />
1620	<xs:enumeration value="N1c" />
1621	<xs:enumeration value="N2" />
1622	<xs:enumeration value="N2a" />
1623	<xs:enumeration value="N2b" />
1624	<xs:enumeration value="N2c" /> <!-- TODO: Make sure that this PV is being procured before sending to DCC. ALSO DELETE THIS COMMENT -->
1625	<xs:enumeration value="N3" />
1626	<xs:enumeration value="N3a" />
1627	<xs:enumeration value="N3b" />
1628	<xs:enumeration value="N3c" />
1629	<xs:enumeration value="N4" />
1630	<xs:attribute name="cde" type="xs:string" default="3203106" />
1631	<xs:attribute name="xsd_ver" type="xs:string" default="2.5" />
1632	<xs:attribute name="tier" type="xs:string" default="1" />
1633	</xs:restriction>
1634	</xs:simpleContent>
1635	</xs:complexType>
1636	</xs:element>
1638	<xs:element name="ajcc_cancer_metastasis_stage_code" nillable="true">	+-
1639	<xs:complexType mixed="true">
1640	<xs:simpleContent>
1641	<xs:restriction base="utility:clinical_res_attributes">
1642	<xs:enumeration value="" />
1643	<xs:enumeration value="cM0 (i+)" />
1644	<xs:enumeration value="M0" />
1645	<xs:enumeration value="M1" />
1646	<xs:enumeration value="M1a" />
1647	<xs:enumeration value="M1b" />
1648	<xs:enumeration value="M1c" />
1649	<xs:enumeration value="M2" /> <!-- TODO: Make sure that this PV is being procured before sending to DCC. ALSO DELETE THIS COMMENT -->
1650	<xs:enumeration value="MX" />
1651	<xs:attribute name="cde" type="xs:string" default="3045439" />
1652	<xs:attribute name="xsd_ver" type="xs:string" default="2.5" />
1653	<xs:attribute name="tier" type="xs:string" default="1" />
1654	</xs:restriction>
1655	</xs:simpleContent>
1656	</xs:complexType>
1657	</xs:element>
1659	<xs:element name="ajcc_neoplasm_disease_stage" nillable="true">	+-
1660	<xs:complexType mixed="true">
1661	<xs:simpleContent>
1662	<xs:restriction base="utility:clinical_res_attributes">
1663	<xs:enumeration value="" />
1664	<xs:enumeration value="Stage X" />
1665	<xs:enumeration value="Stage Tis" />
1666	<xs:enumeration value="Stage 0" />
1667	<xs:enumeration value="Stage I" />
1668	<xs:enumeration value="Stage IA" />
1669	<xs:enumeration value="Stage IB" />
1670	<xs:enumeration value="Stage II" />
1671	<xs:enumeration value="Stage IIA" />
1672	<xs:enumeration value="Stage IIB" />
1673	<xs:enumeration value="Stage IIC" />
1674	<xs:enumeration value="Stage III" />
1675	<xs:enumeration value="Stage IIIA" />
1676	<xs:enumeration value="Stage IIIB" />
1677	<xs:enumeration value="Stage IIIC" />
1678	<xs:enumeration value="Stage IV" />
1679	<xs:enumeration value="Stage IVA" />
1680	<xs:enumeration value="Stage IVB" />
1681	<xs:enumeration value="Stage IIA Cervix" />
1682	<xs:enumeration value="Stage II Cervix" />
1683	<xs:enumeration value="Stage IB2" />
1684	<xs:enumeration value="Stage IB1" />
1685	<xs:enumeration value="Stage IB Cervix" />
1686	<xs:enumeration value="Stage IA2" />
1687	<xs:enumeration value="Stage IA1" />
1688	<xs:enumeration value="Stage IVC" />
1689	<xs:enumeration value="Stage 0is" />
1690	<xs:enumeration value="Stage 0a" />
1691	<xs:attribute name="cde" type="xs:string" default="3203222" />
1692	<xs:attribute name="xsd_ver" type="xs:string" default="2.5" />
1693	<xs:attribute name="tier" type="xs:string" default="2" />
1694	</xs:restriction>
1695	</xs:simpleContent>
1696	</xs:complexType>
1697	</xs:element>
1699	<xs:element name="gynecologic_figo_staging_system" nillable="true">	+-
1700	<xs:complexType mixed="true">
1701	<xs:simpleContent>
1702	<xs:restriction base="utility:clinical_res_attributes">
1703	<xs:enumeration value="" />
1704	<xs:enumeration value="1988" />
1705	<xs:enumeration value="1995" />
1706	<xs:enumeration value="2009" />
1707	<xs:attribute name="cde" type="xs:string" default="3114049" />
1708	<xs:attribute name="xsd_ver" type="xs:string" default="2.4" />
1709	<xs:attribute name="tier" type="xs:string" default="1" />
1710	</xs:restriction>
1711	</xs:simpleContent>
1712	</xs:complexType>
1713	</xs:element>
1715	<xs:element name="karnofsky_performance_score">	+-
1716	<xs:complexType>
1717	<xs:simpleContent>
1718	<xs:restriction base="utility:clinical_res_attributes">
1719	<xs:enumeration value="" />
1720	<xs:enumeration value="0" />
1721	<xs:enumeration value="10" />
1722	<xs:enumeration value="20" />
1723	<xs:enumeration value="30" />
1724	<xs:enumeration value="40" />
1725	<xs:enumeration value="50" />
1726	<xs:enumeration value="60" />
1727	<xs:enumeration value="70" />
1728	<xs:enumeration value="80" />
1729	<xs:enumeration value="90" />
1730	<xs:enumeration value="100" />
1731	<xs:attribute name="cde" type="xs:string" default="2003853" />
1732	<xs:attribute name="xsd_ver" type="xs:string" default="1.8" />
1733	<xs:attribute name="tier" type="xs:string" default="2" />
1734	</xs:restriction>
1735	</xs:simpleContent>
1736	</xs:complexType>
1737	</xs:element>
1739	<xs:element name="eastern_cancer_oncology_group">	+-
1740	<xs:complexType>
1741	<xs:simpleContent>
1742	<xs:restriction base="utility:clinical_res_attributes">
1743	<xs:enumeration value="" />
1744	<xs:enumeration value="0" />
1745	<xs:enumeration value="1" />
1746	<xs:enumeration value="2" />
1747	<xs:enumeration value="3" />
1748	<xs:enumeration value="4" />
1749	<xs:enumeration value="5" />
1750	<xs:attribute name="cde" type="xs:string" default="88" />
1751	<xs:attribute name="xsd_ver" type="xs:string" default="1.9" />
1752	<xs:attribute name="tier" type="xs:string" default="2" />
1753	</xs:restriction>
1754	</xs:simpleContent>
1755	</xs:complexType>
1756	</xs:element>
1758	<xs:element name="followup_case_report_form_submission_reason" nillable="true">	+-
1759	<xs:complexType mixed="true">
1760	<xs:simpleContent>
1761	<xs:restriction base="utility:clinical_res_attributes">
1762	<xs:enumeration value="" />
1763	<xs:enumeration value="Additional New Tumor Event" />
1764	<xs:enumeration value="Scheduled Follow-up Submission" />
1765	<xs:attribute name="cde" type="xs:string" default="3233305" />
1766	<xs:attribute name="xsd_ver" type="xs:string" default="2.5" />
1767	<xs:attribute name="tier" type="xs:string" default="2" />
1768	</xs:restriction>
1769	</xs:simpleContent>
1770	</xs:complexType>
1771	</xs:element>
1779	<xs:element name="primary_lymph_node_presentation_assessment" nillable="true">	+-
1780	<xs:complexType>
1781	<xs:simpleContent>
1782	<xs:extension base="utility:yes_or_no">
1783	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
1784	<xs:attribute name="cde" type="xs:string" default="2200396" />
1785	<xs:attribute name="xsd_ver" type="xs:string" default="2.5" />
1786	<xs:attribute name="tier" type="xs:string" default="2" />
1787	</xs:extension>
1788	</xs:simpleContent>
1789	</xs:complexType>
1790	</xs:element>
1792	<xs:element name="stopped_smoking_year" nillable="true">	+-
1793	<xs:complexType mixed="true">
1794	<xs:simpleContent>
1795	<xs:extension base="utility:generic_year">
1796	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
1797	<xs:attribute name="cde" type="xs:string" default="2228610" />
1798	<xs:attribute name="xsd_ver" type="xs:string" default="2.5" />
1799	<xs:attribute name="tier" type="xs:string" default="1" />
1800	</xs:extension>
1801	</xs:simpleContent>
1802	</xs:complexType>
1803	</xs:element>
1806	<xs:element name="residual_tumor" nillable="true">	+-
1807	<xs:complexType>
1808	<xs:simpleContent>
1809	<xs:restriction base="utility:clinical_res_attributes">
1810	<xs:enumeration value="" />
1811	<xs:enumeration value="R0" />
1812	<xs:enumeration value="R1" />
1813	<xs:enumeration value="R2" />
1814	<xs:enumeration value="RX" />
1815	<xs:attribute name="cde" type="xs:string" default="2608702" />
1816	<xs:attribute name="xsd_ver" type="xs:string" default="2.5" />
1817	<xs:attribute name="tier" type="xs:string" default="1" />
1818	</xs:restriction>
1819	</xs:simpleContent>
1820	</xs:complexType>
1821	</xs:element>
1823	<xs:element name="neoplasm_histologic_grade" nillable="true">	+-
1824	<xs:complexType mixed="true">
1825	<xs:simpleContent>
1826	<xs:restriction base="utility:clinical_res_attributes">
1827	<xs:enumeration value="" />
1828	<xs:enumeration value="G1" />
1829	<xs:enumeration value="G2" />
1830	<xs:enumeration value="G3" />
1831	<xs:enumeration value="G4" />
1832	<xs:enumeration value="GB" />
1833	<xs:enumeration value="GX" />
1834	<xs:attribute name="cde" type="xs:string" default="2785839" />
1835	<xs:attribute name="xsd_ver" type="xs:string" default="2.5" />
1836	<xs:attribute name="tier" type="xs:string" default="1" />
1837	</xs:restriction>
1838	</xs:simpleContent>
1839	</xs:complexType>
1840	</xs:element>
1842	<xs:element name="tumor_histologic_subtype" nillable="true">	+-
1843	<xs:complexType mixed="true">
1844	<xs:simpleContent>
1845	<xs:restriction base="utility:clinical_res_attributes">
1846	<xs:enumeration value="" />
1847	<xs:enumeration value="Adenocarcinoma" />
1848	<xs:enumeration value="Cystadenocarcinoma" />
1849	<xs:enumeration value="Glioblastoma multiforme" />
1850	<xs:enumeration value="Infiltrating Carcinoma NOS" />
1851	<xs:enumeration value="Infiltrating Lobular" />
1852	<xs:enumeration value="Mixed Histology" />
1853	<xs:enumeration value="Muscle invasive urothelial carcinoma" />
1854	<xs:enumeration value="Papillary renal cell carcinoma" />
1855	<xs:enumeration value="Squamous cell carcinoma" />
1856	<xs:attribute name="cde" type="xs:string" default="2831122" />
1857	<xs:attribute name="xsd_ver" type="xs:string" default="2.5" />
1858	<xs:attribute name="tier" type="xs:string" default="1" />
1859	</xs:restriction>
1860	</xs:simpleContent>
1861	</xs:complexType>
1862	</xs:element>
1864	<xs:element name="number_pack_years_smoked" nillable="true">	+-
1865	<xs:complexType>
1866	<xs:simpleContent>
1867	<xs:extension base="utility:number_or_null">
1868	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
1869	<xs:attribute name="cde" type="xs:string" default="2955385" />
1870	<xs:attribute name="xsd_ver" type="xs:string" default="2.5" />
1871	<xs:attribute name="tier" type="xs:string" default="2" />
1872	</xs:extension>
1873	</xs:simpleContent>
1874	</xs:complexType>
1875	</xs:element>
1877	<xs:element name="lymph_node_examined_count" nillable="true">	+-
1878	<xs:complexType>
1879	<xs:simpleContent>
1880	<xs:extension base="utility:integer_or_null">
1881	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
1882	<xs:attribute name="cde" type="xs:string" default="3" />
1883	<xs:attribute name="xsd_ver" type="xs:string" default="2.5" />
1884	<xs:attribute name="tier" type="xs:string" default="2" />
1885	</xs:extension>
1886	</xs:simpleContent>
1887	</xs:complexType>
1888	</xs:element>
1890	<xs:element name="number_of_lymphnodes_positive_by_ihc" nillable="true">	+-
1891	<xs:complexType>
1892	<xs:simpleContent>
1893	<xs:extension base="utility:integer_or_null">
1894	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
1895	<xs:attribute name="cde" type="xs:string" default="3086383" />
1896	<xs:attribute name="xsd_ver" type="xs:string" default="2.5" />
1897	<xs:attribute name="tier" type="xs:string" default="1" />
1898	</xs:extension>
1899	</xs:simpleContent>
1900	</xs:complexType>
1901	</xs:element>
1903	<xs:element name="number_of_lymphnodes_positive_by_he" nillable="true">	+-
1904	<xs:complexType>
1905	<xs:simpleContent>
1906	<xs:extension base="utility:integer_or_null">
1907	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
1908	<xs:attribute name="cde" type="xs:string" default="3086388" />
1909	<xs:attribute name="xsd_ver" type="xs:string" default="2.5" />
1910	<xs:attribute name="tier" type="xs:string" default="2" />
1911	</xs:extension>
1912	</xs:simpleContent>
1913	</xs:complexType>
1914	</xs:element>
1916	<xs:element name="margin_status" nillable="true">	+-
1917	<xs:complexType>
1918	<xs:simpleContent>
1919	<xs:restriction base="utility:clinical_res_attributes">
1920	<xs:enumeration value="" />
1921	<xs:enumeration value="Close" />
1922	<xs:enumeration value="Negative" />
1923	<xs:enumeration value="Positive" />
1924	<xs:attribute name="cde" type="xs:string" default="3114007" />
1925	<xs:attribute name="xsd_ver" type="xs:string" default="2.5" />
1926	<xs:attribute name="tier" type="xs:string" default="1" />
1927	</xs:restriction>
1928	</xs:simpleContent>
1929	</xs:complexType>
1930	</xs:element>
1932	<xs:element name="month_of_performance_status_follow_up_score" nillable="true">	+-
1933	<xs:complexType>
1934	<xs:simpleContent>
1935	<xs:extension base="utility:generic_month">
1936	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
1937	<xs:attribute name="cde" type="xs:string" default="3121370" />
1938	<xs:attribute name="xsd_ver" type="xs:string" default="2.5" />
1939	<xs:attribute name="tier" type="xs:string" default="2" />
1940	</xs:extension>
1941	</xs:simpleContent>
1942	</xs:complexType>
1943	</xs:element>
1945	<xs:element name="day_of_performance_status_follow_up_score" nillable="true">	+-
1946	<xs:complexType>
1947	<xs:simpleContent>
1948	<xs:extension base="utility:generic_day">
1949	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
1950	<xs:attribute name="cde" type="xs:string" default="3121372" />
1951	<xs:attribute name="xsd_ver" type="xs:string" default="2.5" />
1952	<xs:attribute name="tier" type="xs:string" default="2" />
1953	</xs:extension>
1954	</xs:simpleContent>
1955	</xs:complexType>
1956	</xs:element>
1958	<xs:element name="year_of_performance_status_follow_up_score" nillable="true">	+-
1959	<xs:complexType>
1960	<xs:simpleContent>
1961	<xs:extension base="utility:generic_year">
1962	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
1963	<xs:attribute name="cde" type="xs:string" default="3121374" />
1964	<xs:attribute name="xsd_ver" type="xs:string" default="2.5" />
1965	<xs:attribute name="tier" type="xs:string" default="2" />
1966	</xs:extension>
1967	</xs:simpleContent>
1968	</xs:complexType>
1969	</xs:element>
1971	<xs:element name="new_tumor_event_after_initial_treatment" nillable="true">	+-
1972	<xs:complexType>
1973	<xs:simpleContent>
1974	<xs:extension base="utility:yes_or_no">
1975	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
1976	<xs:attribute name="cde" type="xs:string" default="3121376" />
1977	<xs:attribute name="xsd_ver" type="xs:string" default="2.5" />
1978	<xs:attribute name="tier" type="xs:string" default="2" />
1979	</xs:extension>
1980	</xs:simpleContent>
1981	</xs:complexType>
1982	</xs:element>
1984	<xs:element name="residual_disease_post_new_tumor_event_margin_status" nillable="true">	+-
1985	<xs:complexType mixed="true">
1986	<xs:simpleContent>
1987	<xs:restriction base="utility:clinical_res_attributes">
1988	<xs:enumeration value="" />
1989	<xs:enumeration value="R0" />
1990	<xs:enumeration value="R1" />
1991	<xs:enumeration value="R2" />
1992	<xs:enumeration value="RX" />
1993	<xs:attribute name="cde" type="xs:string" default="3104061" />
1994	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
1995	<xs:attribute name="tier" type="xs:string" default="2" />
1996	</xs:restriction>
1997	</xs:simpleContent>
1998	</xs:complexType>
1999	</xs:element>
2001	<xs:element name="tumor_other_histologic_subtype_descriptive_text" nillable="true">	+-
2002	<xs:complexType>
2003	<xs:simpleContent>
2004	<xs:extension base="xs:string">
2005	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
2006	<xs:attribute name="cde" type="xs:string" default="3124492" />
2007	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
2008	<xs:attribute name="tier" type="xs:string" default="1" />
2009	</xs:extension>
2010	</xs:simpleContent>
2011	</xs:complexType>
2012	</xs:element>
2014	<xs:element name="lymphovascular_invasion_present" nillable="true">	+-
2015	<xs:complexType mixed="true">
2016	<xs:simpleContent>
2017	<xs:extension base="utility:yes_or_no">
2018	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
2019	<xs:attribute name="cde" type="xs:string" default="64727" />
2020	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
2021	<xs:attribute name="tier" type="xs:string" default="2" />
2022	</xs:extension>
2023	</xs:simpleContent>
2024	</xs:complexType>
2025	</xs:element>
2027	<xs:element name="followup_treatment_success" nillable="true">	+-
2028	<xs:complexType>
2029	<xs:simpleContent>
2030	<xs:restriction base="utility:clinical_res_attributes">
2031	<xs:enumeration value="" />
2032	<xs:enumeration value="Complete Remission/Response" />
2033	<xs:enumeration value="Not Applicable" />
2034	<xs:enumeration value="Partial Remission/Response" />
2035	<xs:enumeration value="Persistent Disease" />
2036	<xs:enumeration value="Progressive Disease" />
2037	<xs:enumeration value="Stable Disease" />
2038	<xs:enumeration value="Unknown" />
2039	<xs:attribute name="cde" type="xs:string" default="3104050" />
2040	<xs:attribute name="xsd_ver" type="xs:string" default="2.5" />
2041	<xs:attribute name="tier" type="xs:string" default="2" />
2042	</xs:restriction>
2043	</xs:simpleContent>
2044	</xs:complexType>
2045	</xs:element>
2047	<xs:element name="lactate_dehydrogenase_result" nillable="true">	+-
2048	<xs:complexType mixed="true">
2049	<xs:simpleContent>
2050	<xs:restriction base="utility:clinical_res_attributes">
2051	<xs:enumeration value="" />
2052	<xs:enumeration value="Elevated" />
2053	<xs:enumeration value="Low" />
2054	<xs:enumeration value="Normal" />
2055	<xs:attribute name="cde" type="xs:string" default="3113468" />
2056	<xs:attribute name="xsd_ver" type="xs:string" default="2.4" />
2057	<xs:attribute name="tier" type="xs:string" default="2" />
2058	</xs:restriction>
2059	</xs:simpleContent>
2060	</xs:complexType>
2061	</xs:element>
2064	<xs:element name="anatomic_organ_subdivision" nillable="true">	+-
2065	<xs:complexType>
2066	<xs:simpleContent>
2067	<xs:restriction base="utility:clinical_res_attributes">
2068	<xs:enumeration value="" />
2069	<xs:enumeration value="Above" />
2070	<xs:enumeration value="Apex" />
2071	<xs:enumeration value="Anterior" />
2072	<xs:enumeration value="Base" />
2073	<xs:enumeration value="Below" />
2074	<xs:enumeration value="Bilateral" />
2075	<xs:enumeration value="Bladder, NOS" />
2076	<xs:enumeration value="Body" />
2077	<xs:enumeration value="Both" />
2078	<xs:enumeration value="Bronchial" />
2079	<xs:enumeration value="Central" />
2080	<xs:enumeration value="Cerebellar" />
2081	<xs:enumeration value="Cervical" />
2082	<xs:enumeration value="Distal" />
2083	<xs:enumeration value="Dome" />
2084	<xs:enumeration value="Ectopic" />
2085	<xs:enumeration value="Frontal" />
2086	<xs:enumeration value="Fronto-parietal" />
2087	<xs:enumeration value="Head" />
2088	<xs:enumeration value="L-Lower" />
2089	<xs:enumeration value="L-Upper" />
2090	<xs:enumeration value="Lateral" />
2091	<xs:enumeration value="Left" />
2092	<xs:enumeration value="Left Lower Outer Quadrant" />
2093	<xs:enumeration value="Left Lower Inner Quadrant" />
2094	<xs:enumeration value="Left Upper Outer Quadrant" />
2095	<xs:enumeration value="Left Upper Inner Quadrant" />
2096	<xs:enumeration value="Lower" />
2097	<xs:enumeration value="Lower Outer Quadrant" />
2098	<xs:enumeration value="Lower Inner Quadrant" />
2099	<xs:enumeration value="Lumbar" />
2100	<xs:enumeration value="Medial" />
2101	<xs:enumeration value="Mediastinal" />
2102	<xs:enumeration value="Mid" />
2103	<xs:enumeration value="Midline" />
2104	<xs:enumeration value="N/A" />
2105	<xs:enumeration value="Neck" />
2106	<xs:enumeration value="Not a Paired Site" />
2107	<xs:enumeration value="Occipital" />
2108	<xs:enumeration value="Parietal" />
2109	<xs:enumeration value="Posterior" />
2110	<xs:enumeration value="Proximal" />
2111	<xs:enumeration value="R-Lower" />
2112	<xs:enumeration value="R-Middle" />
2113	<xs:enumeration value="R-Upper" />
2114	<xs:enumeration value="Right" />
2115	<xs:enumeration value="Right Lower Outer Quadrant" />
2116	<xs:enumeration value="Right Lower Inner Quadrant" />
2117	<xs:enumeration value="Right Upper Outer Quadrant" />
2118	<xs:enumeration value="Right Upper Inner Quadrant" />
2119	<xs:enumeration value="Supratentorial" />
2120	<xs:enumeration value="Tail" />
2121	<xs:enumeration value="Temporal" />
2122	<xs:enumeration value="Thoracic" />
2123	<xs:enumeration value="Trigone" />
2124	<xs:enumeration value="Upper" />
2125	<xs:enumeration value="Upper Inner Quadrant" />
2126	<xs:enumeration value="Upper Outer Quadrant" />
2127	<xs:enumeration value="Urinary, NOS" />
2128	<xs:enumeration value="Wall, Anterior" />
2129	<xs:enumeration value="Wall, Lateral" />
2130	<xs:enumeration value="Wall, NOS" />
2131	<xs:enumeration value="Wall, Posterior" />
2132	<xs:attribute name="cde" type="xs:string" default="2008006" />
2133	<xs:attribute name="xsd_ver" type="xs:string" default="2.5" />
2134	<xs:attribute name="tier" type="xs:string" default="1" />
2135	</xs:restriction>
2136	</xs:simpleContent>
2137	</xs:complexType>
2138	</xs:element>
2140	<xs:element name="new_neoplasm_event_type" nillable="true">	+-
2141	<xs:complexType mixed="true">
2142	<xs:simpleContent>
2143	<xs:restriction base="utility:clinical_res_attributes">
2144	<xs:enumeration value="" />
2145	<xs:enumeration value="Biochemical evidence of disease" />
2146	<xs:enumeration value="Both Locoregional and Distant Metastasis" />
2147	<xs:enumeration value="Distant Metastasis" />
2148	<xs:enumeration value="Extrahepatic Recurrence" />
2149	<xs:enumeration value="Intrahepatic Recurrence" />
2150	<xs:enumeration value="Locoregional (Urothelial tumor event)" />
2151	<xs:enumeration value="Locoregional Disease" />
2152	<xs:enumeration value="Locoregional Recurrence" />
2153	<xs:enumeration value="Metastatic" />
2154	<xs:enumeration value="New Primary Tumor" />
2155	<xs:enumeration value="No New Tumor Event" />
2156	<xs:enumeration value="Not Applicable" />
2157	<xs:enumeration value="Recurrence" />
2158	<xs:attribute name="cde" type="xs:string" default="3119721" />
2159	<xs:attribute name="xsd_ver" type="xs:string" default="2.5" />
2160	<xs:attribute name="tier" type="xs:string" default="2" />
2161	</xs:restriction>
2162	</xs:simpleContent>
2163	</xs:complexType>
2164	</xs:element>
2166	<xs:element name="followup_met_assessment_outcome_success_margin_status" nillable="true">	+-
2167	<xs:complexType mixed="true">
2168	<xs:simpleContent>
2169	<xs:restriction base="utility:clinical_res_attributes">
2170	<xs:enumeration value="" />
2171	<xs:enumeration value="R0" />
2172	<xs:enumeration value="R1" />
2173	<xs:enumeration value="R2" />
2174	<xs:enumeration value="RX" />
2175	<xs:attribute name="cde" type="xs:string" default="3104081" />
2176	<xs:attribute name="xsd_ver" type="xs:string" default="2.5" />
2177	<xs:attribute name="tier" type="xs:string" default="2" />
2178	</xs:restriction>
2179	</xs:simpleContent>
2180	</xs:complexType>
2181	</xs:element>
2183	<xs:element name="venous_invasion">	+-
2184	<xs:complexType>
2185	<xs:simpleContent>
2186	<xs:extension base="utility:yes_or_no">
2187	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
2188	<xs:attribute name="cde" type="xs:string" default="64358" />
2189	<xs:attribute name="xsd_ver" type="xs:string" default="1.8" />
2190	</xs:extension>
2191	</xs:simpleContent>
2192	</xs:complexType>
2193	</xs:element>
2195	<xs:element name="lymphatic_invasion">	+-
2196	<xs:complexType>
2197	<xs:simpleContent>
2198	<xs:extension base="utility:yes_or_no">
2199	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
2200	<xs:attribute name="cde" type="xs:string" default="64171" />
2201	<xs:attribute name="xsd_ver" type="xs:string" default="1.8" />
2202	</xs:extension>
2203	</xs:simpleContent>
2204	</xs:complexType>
2205	</xs:element>

   
File: TCGA_BCR.Shared_Clinical_KIRC_KIRP_Elements.xsd  

1	<?xml version="1.0" encoding="utf-8"?>	+-
2	<xs:schema elementFormDefault="qualified" version="2.5.0"
3	xmlns:xs="http://www.w3.org/2001/XMLSchema"
4	xmlns:utility="http://tcga.nci/bcr/xml/utility/2.5"
5	xmlns:shared="http://tcga.nci/bcr/xml/clinical/shared/2.5"
6	xmlns:cqcf="http://tcga.nci/bcr/xml/clinical/cqcf/2.5"
7	xmlns="http://tcga.nci/bcr/xml/clinical/shared/kirc_kirp/2.5"
8	targetNamespace="http://tcga.nci/bcr/xml/clinical/shared/kirc_kirp/2.5">
10	<xs:import namespace="http://tcga.nci/bcr/xml/utility/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/utility/2.5/TCGA_BCR.Utility.xsd" />	+-
11	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/shared/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/shared/2.5/TCGA_BCR.Shared_Clinical_Elements.xsd" />
12	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/cqcf/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/cqcf/2.5/TCGA_BCR.CQCF.xsd" />
14	<xs:element name="histological_type" nillable="true">	+-
15	<xs:complexType mixed="true">
16	<xs:simpleContent>
17	<xs:restriction base="utility:clinical_res_attributes">
18	<xs:attribute name="cde" type="xs:string" default="3081934" />
19	<xs:attribute name="xsd_ver" type="xs:string" default="1.9" />
20	<xs:attribute name="tier" type="xs:string" default="1" />
21	</xs:restriction>
22	</xs:simpleContent>
23	</xs:complexType>
24	</xs:element>
28	<xs:element name="primary_tumor_pathologic_spread" nillable="true">	+-
29	<xs:complexType>
30	<xs:simpleContent>
31	<xs:restriction base="utility:clinical_res_attributes">
32	<xs:enumeration value="" />
33	<xs:enumeration value="TX" />
34	<xs:enumeration value="T0" />
35	<xs:enumeration value="T1" />
36	<xs:enumeration value="T1a" />
37	<xs:enumeration value="T1b" />
38	<xs:enumeration value="T2" />
39	<xs:enumeration value="T2a" />
40	<xs:enumeration value="T2b" />
41	<xs:enumeration value="T3" />
42	<xs:enumeration value="T3a" />
43	<xs:enumeration value="T3b" />
44	<xs:enumeration value="T3c" />
45	<xs:enumeration value="T4" />
46	<xs:enumeration value="T4a" />
47	<xs:enumeration value="T4b" />
48	<xs:attribute name="cde" type="xs:string" default="3045435" />
49	<xs:attribute name="xsd_ver" type="xs:string" default="2.1" />
50	<xs:attribute name="tier" type="xs:string" default="1" />
51	</xs:restriction>
52	</xs:simpleContent>
53	</xs:complexType>
54	</xs:element>
56	<xs:element name="lymphnode_pathologic_spread" nillable="true">	+-
57	<xs:complexType>
58	<xs:simpleContent>
59	<xs:restriction base="utility:clinical_res_attributes">
60	<xs:enumeration value="" />
61	<xs:enumeration value="NX" />
62	<xs:enumeration value="N0" />
63	<xs:enumeration value="N1" />
64	<xs:enumeration value="N2" />
65	<xs:enumeration value="N3" />
66	<xs:enumeration value="N4" />
67	<xs:attribute name="cde" type="xs:string" default="3065858" />
68	<xs:attribute name="xsd_ver" type="xs:string" default="2.1" />
69	<xs:attribute name="tier" type="xs:string" default="1" />
70	</xs:restriction>
71	</xs:simpleContent>
72	</xs:complexType>
73	</xs:element>
75	<xs:element name="distant_metastasis_pathologic_spread" nillable="true">	+-
76	<xs:complexType>
77	<xs:simpleContent>
78	<xs:restriction base="utility:clinical_res_attributes">
79	<xs:enumeration value="" />
80	<xs:enumeration value="M0" />
81	<xs:enumeration value="M1" />
82	<xs:enumeration value="MX" />
83	<xs:attribute name="cde" type="xs:string" default="3045439" />
84	<xs:attribute name="xsd_ver" type="xs:string" default="2.1" />
85	<xs:attribute name="tier" type="xs:string" default="1" />
86	</xs:restriction>
87	</xs:simpleContent>
88	</xs:complexType>
89	</xs:element>
93	<xs:element name="number_of_lymphnodes_positive" nillable="true">	+-
94	<xs:complexType mixed="true">
95	<xs:simpleContent>
96	<xs:restriction base="utility:clinical_res_attributes">
97	<xs:attribute name="cde" type="xs:string" default="89" />
98	<xs:attribute name="xsd_ver" type="xs:string" default="2.1" />
99	<xs:attribute name="tier" type="xs:string" default="1" />
100	</xs:restriction>
101	</xs:simpleContent>
102	</xs:complexType>
103	</xs:element>
105	<xs:element name="erythrocyte_sedimentation_rate_result" nillable="true">	+-
106	<xs:complexType>
107	<xs:simpleContent>
108	<xs:restriction base="utility:clinical_res_attributes">
109	<xs:enumeration value="" />
110	<xs:enumeration value="Elevated" />
111	<xs:enumeration value="Normal" />
112	<xs:attribute name="cde" type="xs:string" default="3104952" />
113	<xs:attribute name="xsd_ver" type="xs:string" default="2.1" />
114	<xs:attribute name="tier" type="xs:string" default="1" />
115	</xs:restriction>
116	</xs:simpleContent>
117	</xs:complexType>
118	</xs:element>
120	<xs:element name="white_cell_count_result" nillable="true">	+-
121	<xs:complexType>
122	<xs:simpleContent>
123	<xs:restriction base="utility:clinical_res_attributes">
124	<xs:enumeration value="" />
125	<xs:enumeration value="Elevated" />
126	<xs:enumeration value="Normal" />
127	<xs:enumeration value="Low" />
128	<xs:attribute name="cde" type="xs:string" default="3104948" />
129	<xs:attribute name="xsd_ver" type="xs:string" default="2.1" />
130	<xs:attribute name="tier" type="xs:string" default="1" />
131	</xs:restriction>
132	</xs:simpleContent>
133	</xs:complexType>
134	</xs:element>
136	<xs:element name="platelet_qualitative_result" nillable="true">	+-
137	<xs:complexType>
138	<xs:simpleContent>
139	<xs:restriction base="utility:clinical_res_attributes">
140	<xs:enumeration value="" />
141	<xs:enumeration value="Elevated" />
142	<xs:enumeration value="Normal" />
143	<xs:enumeration value="Low" />
144	<xs:attribute name="cde" type="xs:string" default="3104944" />
145	<xs:attribute name="xsd_ver" type="xs:string" default="2.1" />
146	<xs:attribute name="tier" type="xs:string" default="1" />
147	</xs:restriction>
148	</xs:simpleContent>
149	</xs:complexType>
150	</xs:element>
152	<xs:element name="hemoglobin_result" nillable="true">	+-
153	<xs:complexType>
154	<xs:simpleContent>
155	<xs:restriction base="utility:clinical_res_attributes">
156	<xs:enumeration value="" />
157	<xs:enumeration value="Elevated" />
158	<xs:enumeration value="Normal" />
159	<xs:enumeration value="Low" />
160	<xs:attribute name="cde" type="xs:string" default="3113466" />
161	<xs:attribute name="xsd_ver" type="xs:string" default="2.1" />
162	<xs:attribute name="tier" type="xs:string" default="1" />
163	</xs:restriction>
164	</xs:simpleContent>
165	</xs:complexType>
166	</xs:element>
168	<xs:element name="serum_calcium_result" nillable="true">	+-
169	<xs:complexType>
170	<xs:simpleContent>
171	<xs:restriction base="utility:clinical_res_attributes">
172	<xs:enumeration value="" />
173	<xs:enumeration value="Elevated" />
174	<xs:enumeration value="Normal" />
175	<xs:enumeration value="Low" />
176	<xs:attribute name="cde" type="xs:string" default="3113470" />
177	<xs:attribute name="xsd_ver" type="xs:string" default="2.1" />
178	<xs:attribute name="tier" type="xs:string" default="1" />
179	</xs:restriction>
180	</xs:simpleContent>
181	</xs:complexType>
182	</xs:element>
184	<xs:element name="lactate_dehydrogenase_result" nillable="true">	+-
185	<xs:complexType>
186	<xs:simpleContent>
187	<xs:restriction base="utility:clinical_res_attributes">
188	<xs:enumeration value="" />
189	<xs:enumeration value="Elevated" />
190	<xs:enumeration value="Normal" />
191	<xs:attribute name="cde" type="xs:string" default="3113468" />
192	<xs:attribute name="xsd_ver" type="xs:string" default="2.1" />
193	<xs:attribute name="tier" type="xs:string" default="1" />
194	</xs:restriction>
195	</xs:simpleContent>
196	</xs:complexType>
197	</xs:element>
199	<xs:element name="laterality" nillable="true">	+-
200	<xs:complexType>
201	<xs:simpleContent>
202	<xs:restriction base="utility:clinical_res_attributes">
203	<xs:enumeration value="" />
204	<xs:enumeration value="Right" />
205	<xs:enumeration value="Left" />
206	<xs:enumeration value="Bilateral" />
207	<xs:attribute name="cde" type="xs:string" default="827" />
208	<xs:attribute name="xsd_ver" type="xs:string" default="2.1" />
209	<xs:attribute name="tier" type="xs:string" default="1" />
210	</xs:restriction>
211	</xs:simpleContent>
212	</xs:complexType>
213	</xs:element>
217	<xs:element name="tumor_stage" nillable="true">	+-
218	<xs:complexType>
219	<xs:simpleContent>
220	<xs:restriction base="utility:clinical_res_attributes">
221	<xs:enumeration value="" />
222	<xs:enumeration value="Stage I" />
223	<xs:enumeration value="Stage II" />
224	<xs:enumeration value="Stage III" />
225	<xs:enumeration value="Stage IV" />
226	<xs:attribute name="cde" type="xs:string" default="3065862" />
227	<xs:attribute name="xsd_ver" type="xs:string" default="1.11" />
228	<xs:attribute name="tier" type="xs:string" default="1" />
229	</xs:restriction>
230	</xs:simpleContent>
231	</xs:complexType>
232	</xs:element>
235	</xs:schema>	+-

   
File: TCGA_BCR.Shared_Clinical_LUSC_LUAD_Elements.xsd  

1	<?xml version="1.0" encoding="utf-8"?>	+-
3	<xs:schema xmlns:xs="http://www.w3.org/2001/XMLSchema" xmlns:utility="http://tcga.nci/bcr/xml/utility/2.5" xmlns:shared="http://tcga.nci/bcr/xml/clinical/shared/2.5" xmlns:cqcf="http://tcga.nci/bcr/xml/clinical/cqcf/2.5" xmlns="http://tcga.nci/bcr/xml/clinical/shared/lusc_luad/2.5" targetNamespace="http://tcga.nci/bcr/xml/clinical/shared/lusc_luad/2.5" elementFormDefault="qualified" version="2.5.0">	+-
4	<xs:import namespace="http://tcga.nci/bcr/xml/utility/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/utility/2.5/TCGA_BCR.Utility.xsd"/>
5	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/shared/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/shared/2.5/TCGA_BCR.Shared_Clinical_Elements.xsd"/>
6	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/cqcf/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/cqcf/2.5/TCGA_BCR.CQCF.xsd"/>
7	<xs:element name="egfr_mutation_result" nillable="true">
8	<xs:complexType mixed="true">
9	<xs:simpleContent>
10	<xs:restriction base="utility:clinical_res_attributes">
11	<xs:enumeration value=""/>
12	<xs:enumeration value="G719X"/>
13	<xs:enumeration value="Exon 19 Deletion"/>
14	<xs:enumeration value="Exon 20 Insertion"/>
15	<xs:enumeration value="T790M"/>
16	<xs:enumeration value="L858R"/>
17	<xs:enumeration value="L861Q"/>
18	<xs:enumeration value="Other"/>
19	<xs:attribute name="cde" type="xs:string" default="3147627"/>
20	<xs:attribute name="xsd_ver" type="xs:string" default="2.3"/>
21	<xs:attribute name="tier" type="xs:string" default="2"/>
22	</xs:restriction>
23	</xs:simpleContent>
24	</xs:complexType>
25	</xs:element>
26	<xs:element name="eml4_alk_translocation_result" nillable="true">
27	<xs:complexType mixed="true">
28	<xs:simpleContent>
29	<xs:restriction base="utility:clinical_res_attributes">
30	<xs:enumeration value=""/>
31	<xs:enumeration value="Variant 1"/>
32	<xs:enumeration value="Variant 2"/>
33	<xs:enumeration value="Variant 3"/>
34	<xs:enumeration value="Variant 4"/>
35	<xs:enumeration value="Variant 5"/>
36	<xs:attribute name="cde" type="xs:string" default="3139445"/>
37	<xs:attribute name="xsd_ver" type="xs:string" default="2.3"/>
38	<xs:attribute name="tier" type="xs:string" default="2"/>
39	</xs:restriction>
40	</xs:simpleContent>
41	</xs:complexType>
42	</xs:element>
43	<xs:element name="eml4_alk_translocation_method" nillable="true">
44	<xs:complexType mixed="true">
45	<xs:simpleContent>
46	<xs:restriction base="utility:clinical_res_attributes">
47	<xs:enumeration value=""/>
48	<xs:enumeration value="IHC"/>
49	<xs:enumeration value="FISH"/>
50	<xs:enumeration value="RT-PCR"/>
51	<xs:enumeration value="Other"/>
52	<xs:attribute name="cde" type="xs:string" default="3139449"/>
53	<xs:attribute name="xsd_ver" type="xs:string" default="2.3"/>
54	<xs:attribute name="tier" type="xs:string" default="2"/>
55	</xs:restriction>
56	</xs:simpleContent>
57	</xs:complexType>
58	</xs:element>
59	<xs:element name="egfr_mutation_performed" nillable="true">
60	<xs:complexType>
61	<xs:simpleContent>
62	<xs:extension base="utility:yes_or_no">
63	<xs:attributeGroup ref="utility:common_ext_attribute_group"/>
64	<xs:attribute name="cde" type="xs:string" default="3139429"/>
65	<xs:attribute name="xsd_ver" type="xs:string" default="2.3"/>
66	<xs:attribute name="tier" type="xs:string" default="1"/>
67	</xs:extension>
68	</xs:simpleContent>
69	</xs:complexType>
70	</xs:element>
71	<xs:element name="eml4_alk_translocation_performed" nillable="true">
72	<xs:complexType>
73	<xs:simpleContent>
74	<xs:extension base="utility:yes_or_no">
75	<xs:attributeGroup ref="utility:common_ext_attribute_group"/>
76	<xs:attribute name="cde" type="xs:string" default="3139437"/>
77	<xs:attribute name="xsd_ver" type="xs:string" default="2.3"/>
78	<xs:attribute name="tier" type="xs:string" default="1"/>
79	</xs:extension>
80	</xs:simpleContent>
81	</xs:complexType>
82	</xs:element>
83	<xs:element name="histological_type" nillable="true">
84	<xs:complexType mixed="true">
85	<xs:simpleContent>
86	<xs:restriction base="utility:clinical_res_attributes">
87	<xs:attribute name="cde" type="xs:string" default="3081934"/>
88	<xs:attribute name="xsd_ver" type="xs:string" default="1.9"/>
89	<xs:attribute name="tier" type="xs:string" default="1"/>
90	</xs:restriction>
91	</xs:simpleContent>
92	</xs:complexType>
93	</xs:element>
94	<xs:element name="diagnosis" nillable="true">
95	<xs:complexType mixed="true">
96	<xs:simpleContent>
97	<xs:restriction base="utility:clinical_res_attributes">
98	<xs:attribute name="cde" type="xs:string" default="3081932"/>
99	<xs:attribute name="xsd_ver" type="xs:string" default="2.3"/>
100	<xs:attribute name="tier" type="xs:string" default="1"/>
101	</xs:restriction>
102	</xs:simpleContent>
103	</xs:complexType>
104	</xs:element>
105	<xs:element name="location_in_lung_parenchyma" nillable="true">
106	<xs:complexType mixed="true">
107	<xs:simpleContent>
108	<xs:restriction base="utility:clinical_res_attributes">
109	<xs:enumeration value=""/>
110	<xs:enumeration value="Peripheral Lung"/>
111	<xs:enumeration value="Central Lung"/>
112	<xs:attribute name="cde" type="xs:string" default="3139453"/>
113	<xs:attribute name="xsd_ver" type="xs:string" default="2.3"/>
114	<xs:attribute name="tier" type="xs:string" default="2"/>
115	</xs:restriction>
116	</xs:simpleContent>
117	</xs:complexType>
118	</xs:element>
119	<xs:element name="kras_mutation_result" nillable="true">
120	<xs:complexType mixed="true">
121	<xs:simpleContent>
122	<xs:restriction base="utility:clinical_res_attributes">
123	<xs:enumeration value=""/>
124	<xs:enumeration value="G12A"/>
125	<xs:enumeration value="G12C"/>
126	<xs:enumeration value="G12D"/>
127	<xs:enumeration value="G12R"/>
128	<xs:enumeration value="G12S"/>
129	<xs:enumeration value="G12V"/>
130	<xs:enumeration value="G13D"/>
131	<xs:enumeration value="Other"/>
132	<xs:attribute name="cde" type="xs:string" default="3147614"/>
133	<xs:attribute name="xsd_ver" type="xs:string" default="2.3"/>
134	<xs:attribute name="tier" type="xs:string" default="2"/>
135	</xs:restriction>
136	</xs:simpleContent>
137	</xs:complexType>
138	</xs:element>
139	<xs:element name="tobacco_smoking_history_indicator" nillable="true">
140	<xs:complexType>
141	<xs:simpleContent>
142	<xs:restriction base="utility:clinical_res_attributes">
143	<xs:enumeration value=""/>
144	<xs:enumeration value="Lifelong Non-smoker"/>
145	<xs:enumeration value="Current smoker"/>
146	<xs:enumeration value="Current reformed smoker for &gt; 15 years"/>
147	<xs:enumeration value="Current reformed smoker for &lt; or = 15 years"/>
148	<xs:attribute name="cde" type="xs:string" default="2181650"/>
149	<xs:attribute name="xsd_ver" type="xs:string" default="2.3"/>
150	<xs:attribute name="tier" type="xs:string" default="1"/>
151	</xs:restriction>
152	</xs:simpleContent>
153	</xs:complexType>
154	</xs:element>
155	<xs:element name="year_of_tobacco_smoking_onset" nillable="true">
156	<xs:complexType mixed="true">
157	<xs:simpleContent>
158	<xs:extension base="utility:generic_year">
159	<xs:attributeGroup ref="utility:common_ext_attribute_group"/>
160	<xs:attribute name="cde" type="xs:string" default="2228604"/>
161	<xs:attribute name="xsd_ver" type="xs:string" default="2.3"/>
162	<xs:attribute name="tier" type="xs:string" default="1"/>
163	</xs:extension>
164	</xs:simpleContent>
165	</xs:complexType>
166	</xs:element>
167	<xs:element name="kras_mutation_found" nillable="true">
168	<xs:complexType>
169	<xs:simpleContent>
170	<xs:extension base="utility:yes_or_no">
171	<xs:attributeGroup ref="utility:common_ext_attribute_group"/>
172	<xs:attribute name="cde" type="xs:string" default="2932340"/>
173	<xs:attribute name="xsd_ver" type="xs:string" default="2.3"/>
174	<xs:attribute name="tier" type="xs:string" default="1"/>
175	</xs:extension>
176	</xs:simpleContent>
177	</xs:complexType>
178	</xs:element>
179	<xs:element name="kras_gene_analysis_performed" nillable="true">
180	<xs:complexType>
181	<xs:simpleContent>
182	<xs:extension base="utility:yes_or_no">
183	<xs:attributeGroup ref="utility:common_ext_attribute_group"/>
184	<xs:attribute name="cde" type="xs:string" default="3123147"/>
185	<xs:attribute name="xsd_ver" type="xs:string" default="2.3"/>
186	<xs:attribute name="tier" type="xs:string" default="1"/>
187	</xs:extension>
188	</xs:simpleContent>
189	</xs:complexType>
190	</xs:element>
191	<xs:element name="residual_tumor" nillable="true">
192	<xs:complexType>
193	<xs:simpleContent>
194	<xs:restriction base="utility:clinical_res_attributes">
195	<xs:enumeration value=""/>
196	<xs:enumeration value="RX"/>
197	<xs:enumeration value="R0"/>
198	<xs:enumeration value="R1"/>
199	<xs:enumeration value="R2"/>
200	<xs:attribute name="cde" type="xs:string" default="2608702"/>
201	<xs:attribute name="xsd_ver" type="xs:string" default="1.11"/>
202	<xs:attribute name="tier" type="xs:string" default="1"/>
203	</xs:restriction>
204	</xs:simpleContent>
205	</xs:complexType>
206	</xs:element>
207	<xs:element name="primary_tumor_pathologic_spread" nillable="true">
208	<xs:complexType>
209	<xs:simpleContent>
210	<xs:restriction base="utility:clinical_res_attributes">
211	<xs:enumeration value=""/>
212	<xs:enumeration value="TX"/>
213	<xs:enumeration value="T0"/>
214	<xs:enumeration value="Tis"/>
215	<xs:enumeration value="T1"/>
216	<xs:enumeration value="T1a"/>
217	<xs:enumeration value="T1b"/>
218	<xs:enumeration value="T2"/>
219	<xs:enumeration value="T2a"/>
220	<xs:enumeration value="T2b"/>
221	<xs:enumeration value="T3"/>
222	<xs:enumeration value="T4"/>
223	<xs:attribute name="cde" type="xs:string" default="3045435"/>
224	<xs:attribute name="xsd_ver" type="xs:string" default="2.1"/>
225	<xs:attribute name="tier" type="xs:string" default="1"/>
226	</xs:restriction>
227	</xs:simpleContent>
228	</xs:complexType>
229	</xs:element>
230	<xs:element name="lymphnode_pathologic_spread" nillable="true">
231	<xs:complexType>
232	<xs:simpleContent>
233	<xs:restriction base="utility:clinical_res_attributes">
234	<xs:enumeration value=""/>
235	<xs:enumeration value="NX"/>
236	<xs:enumeration value="N0"/>
237	<xs:enumeration value="N1"/>
238	<xs:enumeration value="N2"/>
239	<xs:enumeration value="N3"/>
240	<xs:attribute name="cde" type="xs:string" default="3065858"/>
241	<xs:attribute name="xsd_ver" type="xs:string" default="2.1"/>
242	<xs:attribute name="tier" type="xs:string" default="1"/>
243	</xs:restriction>
244	</xs:simpleContent>
245	</xs:complexType>
246	</xs:element>
247	<xs:element name="distant_metastasis_pathologic_spread" nillable="true">
248	<xs:complexType>
249	<xs:simpleContent>
250	<xs:restriction base="utility:clinical_res_attributes">
251	<xs:enumeration value=""/>
252	<xs:enumeration value="M0"/>
253	<xs:enumeration value="M1"/>
254	<xs:enumeration value="M1a"/>
255	<xs:enumeration value="M1b"/>
256	<xs:enumeration value="MX"/>
257	<xs:attribute name="cde" type="xs:string" default="3045439"/>
258	<xs:attribute name="xsd_ver" type="xs:string" default="2.4"/>
259	<xs:attribute name="tier" type="xs:string" default="1"/>
260	</xs:restriction>
261	</xs:simpleContent>
262	</xs:complexType>
263	</xs:element>
264	<xs:element name="tumor_stage" nillable="true">
265	<xs:complexType>
266	<xs:simpleContent>
267	<xs:restriction base="utility:clinical_res_attributes">
268	<xs:enumeration value=""/>
269	<xs:enumeration value="Stage I"/>
270	<xs:enumeration value="Stage IA"/>
271	<xs:enumeration value="Stage IB"/>
272	<xs:enumeration value="Stage II"/>
273	<xs:enumeration value="Stage IIA"/>
274	<xs:enumeration value="Stage IIB"/>
275	<xs:enumeration value="Stage III"/>
276	<xs:enumeration value="Stage IIIA"/>
277	<xs:enumeration value="Stage IIIB"/>
278	<xs:enumeration value="Stage IV"/>
279	<xs:attribute name="cde" type="xs:string" default="3065862"/>
280	<xs:attribute name="xsd_ver" type="xs:string" default="2.4"/>
281	<xs:attribute name="tier" type="xs:string" default="1"/>
282	</xs:restriction>
283	</xs:simpleContent>
284	</xs:complexType>
285	</xs:element>
286	<xs:element name="clinical_cqcf">
287	<xs:complexType>
288	<xs:sequence>
289	<xs:element ref="shared:anatomic_organ_subdivision"/>
290	<xs:element ref="cqcf:history_of_prior_malignancy"/>
291	<xs:element ref="cqcf:history_of_neoadjuvant_treatment"/>
292	<xs:element ref="cqcf:consent_or_death_status"/>
293	<xs:choice>
294	<xs:choice>
295	<xs:sequence>
296	<xs:element ref="cqcf:day_of_consent"/>
297	<xs:element ref="cqcf:month_of_consent"/>
298	<xs:element ref="cqcf:year_of_consent"/>
299	</xs:sequence>
300	<xs:element ref="cqcf:days_to_consent"/>
301	</xs:choice>
302	<xs:choice>
303	<xs:sequence>
304	<xs:element ref="shared:day_of_death"/>
305	<xs:element ref="shared:month_of_death"/>
306	<xs:element ref="shared:year_of_death"/>
307	</xs:sequence>
308	<xs:element ref="shared:days_to_death"/>
309	</xs:choice>
310	</xs:choice>
311	<xs:element ref="cqcf:diagnosis_subtype"/>
312	<xs:element ref="shared:prior_diagnosis"/>
313	<xs:element ref="cqcf:normal_tissue_anatomic_site"/>
314	<xs:element ref="cqcf:normal_tissue_proximity"/>
315	<xs:element ref="cqcf:tumor_type"/>
316	<xs:element ref="cqcf:histological_subtype" minOccurs="0"/>
317	<xs:element ref="cqcf:other_anatomic_site" minOccurs="0"/>
318	<xs:element ref="cqcf:country"/>
319	</xs:sequence>
320	</xs:complexType>
321	</xs:element>
322	</xs:schema>

   
File: TCGA_BCR.SKCM_Clinical.xsd  

4	<xs:schema elementFormDefault="qualified" version="2.5.0"	<>	4	<xs:schema elementFormDefault="qualified" version="2.4.4"
6	xmlns:utility="http://tcga.nci/bcr/xml/utility/2.5"	<>	6	xmlns:utility="http://tcga.nci/bcr/xml/utility/2.4"
7	xmlns:admin="http://tcga.nci/bcr/xml/administration/2.5"		7	xmlns:admin="http://tcga.nci/bcr/xml/administration/2.4"
8	xmlns:shared="http://tcga.nci/bcr/xml/clinical/shared/2.5"		8	xmlns:shared="http://tcga.nci/bcr/xml/clinical/shared/2.4"
9	xmlns:rad="http://tcga.nci/bcr/xml/clinical/radiation/2.5"		9	xmlns:rad="http://tcga.nci/bcr/xml/clinical/radiation/2.4"
10	xmlns:rx="http://tcga.nci/bcr/xml/clinical/pharmaceutical/2.5"		10	xmlns:rx="http://tcga.nci/bcr/xml/clinical/pharmaceutical/2.4"
11	xmlns:cqcf="http://tcga.nci/bcr/xml/clinical/cqcf/2.5"
12	xmlns:cesc_shared="http://tcga.nci/bcr/xml/clinical/skcm/shared/2.5"
13	xmlns:follow_up_v2.0="http://tcga.nci/bcr/xml/clinical/skcm/followup/2.5/2.0"
14	xmlns="http://tcga.nci/bcr/xml/clinical/skcm/2.5"		11	xmlns="http://tcga.nci/bcr/xml/clinical/skcm/2.4"
15	targetNamespace="http://tcga.nci/bcr/xml/clinical/skcm/2.5"		12	targetNamespace="http://tcga.nci/bcr/xml/clinical/skcm/2.4"
31	<xs:import namespace="http://tcga.nci/bcr/xml/utility/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/utility/2.5/TCGA_BCR.Utility.xsd" />	<>	28	<xs:import namespace="http://tcga.nci/bcr/xml/utility/2.4" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/utility/2.4/TCGA_BCR.Utility.xsd" />
32	<xs:import namespace="http://tcga.nci/bcr/xml/administration/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/administration/2.5/TCGA_BCR.Administration.xsd" />		29	<xs:import namespace="http://tcga.nci/bcr/xml/administration/2.4" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/administration/2.4/TCGA_BCR.Administration.xsd" />
33	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/shared/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/shared/2.5/TCGA_BCR.Shared_Clinical_Elements.xsd" />		30	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/shared/2.4" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/shared/2.4/TCGA_BCR.Shared_Clinical_Elements.xsd" />
34	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/radiation/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/radiation/2.5/TCGA_BCR.Radiation.xsd" />		31	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/radiation/2.4" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/radiation/2.4/TCGA_BCR.Radiation.xsd" />
35	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/pharmaceutical/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/pharmaceutical/2.5/TCGA_BCR.Pharmaceutical.xsd" />		32	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/pharmaceutical/2.4" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/pharmaceutical/2.4/TCGA_BCR.Pharmaceutical.xsd" />
36	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/cqcf/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/cqcf/2.5/TCGA_BCR.CQCF.xsd" />
37	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/skcm/shared/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/skcm/shared/2.5/TCGA_BCR.SKCM_Clinical_Shared_Datatypes.xsd" />
38	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/skcm/followup/2.5/2.0" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/skcm/followup/2.5/TCGA_BCR.SKCM_Clinical_FollowUp_v2.0.xsd" />
101	<xs:element ref="shared:ajcc_tumor_stage_code" />	<>	95	<xs:element ref="ajcc_tumor_stage_code" />
102	<xs:element ref="shared:ajcc_neoplasm_disease_lymph_node_stage" />		96	<xs:element ref="ajcc_neoplasm_disease_lymph_node_stage" />
103	<xs:element ref="shared:ajcc_cancer_metastasis_stage_code" />		97	<xs:element ref="ajcc_cancer_metastasis_stage_code" />
104	<xs:element ref="shared:ajcc_neoplasm_disease_stage" />		98	<xs:element ref="ajcc_neoplasm_disease_stage" />
124	<xs:element ref="melanoma_ulceration_indicator" />	+-
		-+	119	<xs:element ref="melanoma_ulceration_indicator" />
132	<xs:element ref="shared:lactate_dehydrogenase_result" />	<>	126	<xs:element ref="lab_procedure_lactate_dehydrogenase_summary" />
142	<xs:element ref="follow_ups" />	+-
145	<xs:element ref="clinical_cqcf" />	+-
146	</xs:sequence>
147	</xs:complexType>
148	</xs:element>
150	<xs:element name="follow_ups">	+-
151	<xs:annotation>
152	<xs:documentation xml:lang="en">We are using namespaces and version numbers to distinguish one version of followup from another.</xs:documentation>
153	</xs:annotation>
154	<xs:complexType>
155	<xs:sequence>
156	<xs:element ref="follow_up_v2.0:follow_up_v2.0" minOccurs="0" maxOccurs="unbounded" />
157	</xs:sequence>
158	</xs:complexType>
159	</xs:element>
161	<xs:element name="clinical_cqcf">	+-
162	<xs:complexType>
163	<xs:sequence>
164	<xs:element ref="shared:anatomic_organ_subdivision"/>
165	<xs:element ref="cqcf:consent_or_death_status"/>
167	<xs:choice>	+-
168	<xs:choice>
169	<xs:sequence>
170	<xs:element ref="cqcf:day_of_consent"/>
171	<xs:element ref="cqcf:month_of_consent"/>
172	<xs:element ref="cqcf:year_of_consent"/>
173	</xs:sequence>
175	<xs:element ref="cqcf:days_to_consent"/>	+-
176	</xs:choice>
178	<xs:choice>	+-
179	<xs:sequence>
180	<xs:element ref="shared:day_of_death"/>
181	<xs:element ref="shared:month_of_death"/>
182	<xs:element ref="shared:year_of_death"/>
183	</xs:sequence>
185	<xs:element ref="shared:days_to_death"/>	+-
186	</xs:choice>
187	</xs:choice>
189	<xs:element ref="cqcf:diagnosis_subtype"/>	+-
190	<xs:element ref="shared:prior_diagnosis"/>
191	<xs:element ref="cqcf:history_of_neoadjuvant_treatment"/>
192	<xs:element ref="cqcf:normal_tissue_anatomic_site"/>
193	<xs:element ref="cqcf:normal_tissue_proximity"/>
194	<xs:element ref="cqcf:tumor_focality"/>
195	<xs:element ref="cqcf:tumor_type"/>
196	<xs:element ref="cqcf:other_diagnosis"/>
197	<xs:element ref="cqcf:histological_subtype" minOccurs="0"/>
198	<xs:element ref="cqcf:other_anatomic_site" minOccurs="0"/>
199	<xs:element ref="cqcf:country"/>
		-+	334	<xs:element name="lab_procedure_lactate_dehydrogenase_summary" nillable="true">
			335	<xs:complexType mixed="true">
			336	<xs:simpleContent>
			337	<xs:restriction base="utility:clinical_res_attributes">
			338	<xs:enumeration value="" />
			339	<xs:enumeration value="Elevated" />
			340	<xs:enumeration value="Low" />
			341	<xs:enumeration value="Normal" />
			342	<xs:attribute name="cde" type="xs:string" default="3113468" />
			343	<xs:attribute name="xsd_ver" type="xs:string" default="2.4" />
			344	<xs:attribute name="tier" type="xs:string" default="2" />
			345	</xs:restriction>
			346	</xs:simpleContent>
			347	</xs:complexType>
			348	</xs:element>
		-+	350	<xs:element name="ajcc_tumor_stage_code" nillable="true">
			351	<xs:complexType mixed="true">
			352	<xs:simpleContent>
			353	<xs:restriction base="utility:clinical_res_attributes">
			354	<xs:enumeration value="" />
			355	<xs:enumeration value="T0" />
			356	<xs:enumeration value="Ta" />
			357	<xs:enumeration value="T1" />
			358	<xs:enumeration value="T1a" />
			359	<xs:enumeration value="T1a1" />
			360	<xs:enumeration value="T1a2" />
			361	<xs:enumeration value="T1b" />
			362	<xs:enumeration value="T1c" />
			363	<xs:enumeration value="T1mi" />
			364	<xs:enumeration value="T2" />
			365	<xs:enumeration value="T2a" />
			366	<xs:enumeration value="T2a1" />
			367	<xs:enumeration value="T2a2" />
			368	<xs:enumeration value="T2b" />
			369	<xs:enumeration value="T2c" />
			370	<xs:enumeration value="T3" />
			371	<xs:enumeration value="T3a" />
			372	<xs:enumeration value="T3b" />
			373	<xs:enumeration value="T3c" />
			374	<xs:enumeration value="T4" />
			375	<xs:enumeration value="T4a" />
			376	<xs:enumeration value="T4b" />
			377	<xs:enumeration value="T4c" />
			378	<xs:enumeration value="T4d" />
			379	<xs:enumeration value="Tis" />
			380	<xs:enumeration value="Tis (DCIS)" />
			381	<xs:enumeration value="Tis (LCIS)" />
			382	<xs:enumeration value="Tis (Paget's)" />
			383	<xs:enumeration value="TX" />
			384	<xs:attribute name="cde" type="xs:string" default="3045435" />
			385	<xs:attribute name="xsd_ver" type="xs:string" default="2.5" />
			386	<xs:attribute name="tier" type="xs:string" default="1" />
			387	</xs:restriction>
			388	</xs:simpleContent>
			389	</xs:complexType>
			390	</xs:element>
		-+	392	<xs:element name="ajcc_neoplasm_disease_lymph_node_stage" nillable="true">
			393	<xs:complexType mixed="true">
			394	<xs:simpleContent>
			395	<xs:restriction base="utility:clinical_res_attributes">
			396	<xs:enumeration value="" />
			397	<xs:enumeration value="NX" />
			398	<xs:enumeration value="N0" />
			399	<xs:enumeration value="N0 (i-)" />
			400	<xs:enumeration value="N0 (i+)" />
			401	<xs:enumeration value="N0 (mol-)" />
			402	<xs:enumeration value="N0 (mol+)" />
			403	<xs:enumeration value="N1" />
			404	<xs:enumeration value="N1mi" />
			405	<xs:enumeration value="N1a" />
			406	<xs:enumeration value="N1b" />
			407	<xs:enumeration value="N1bI" />
			408	<xs:enumeration value="N1bII" />
			409	<xs:enumeration value="N1bIII" />
			410	<xs:enumeration value="N1bIV" />
			411	<xs:enumeration value="N1c" />
			412	<xs:enumeration value="N2" />
			413	<xs:enumeration value="N2a" />
			414	<xs:enumeration value="N2b" />
			415	<xs:enumeration value="N3" />
			416	<xs:enumeration value="N3a" />
			417	<xs:enumeration value="N3b" />
			418	<xs:enumeration value="N3c" />
			419	<xs:enumeration value="N4" />
			420	<xs:attribute name="cde" type="xs:string" default="3203106" />
			421	<xs:attribute name="xsd_ver" type="xs:string" default="2.5" />
			422	<xs:attribute name="tier" type="xs:string" default="1" />
			423	</xs:restriction>
			424	</xs:simpleContent>
			425	</xs:complexType>
			426	</xs:element>
		-+	428	<xs:element name="ajcc_cancer_metastasis_stage_code" nillable="true">
			429	<xs:complexType mixed="true">
			430	<xs:simpleContent>
			431	<xs:restriction base="utility:clinical_res_attributes">
			432	<xs:enumeration value="" />
			433	<xs:enumeration value="cM0 (i+)" />
			434	<xs:enumeration value="M0" />
			435	<xs:enumeration value="M1" />
			436	<xs:enumeration value="M1a" />
			437	<xs:enumeration value="M1b" />
			438	<xs:enumeration value="M1c" />
			439	<xs:enumeration value="MX" />
			440	<xs:attribute name="cde" type="xs:string" default="3045439" />
			441	<xs:attribute name="xsd_ver" type="xs:string" default="2.5" />
			442	<xs:attribute name="tier" type="xs:string" default="1" />
			443	</xs:restriction>
			444	</xs:simpleContent>
			445	</xs:complexType>
			446	</xs:element>
		-+	448	<xs:element name="ajcc_neoplasm_disease_stage" nillable="true">
			449	<xs:complexType mixed="true">
			450	<xs:simpleContent>
			451	<xs:restriction base="utility:clinical_res_attributes">
			452	<xs:enumeration value="" />
			453	<xs:enumeration value="Stage X" />
			454	<xs:enumeration value="Stage Tis" />
			455	<xs:enumeration value="Stage 0" />
			456	<xs:enumeration value="Stage I" />
			457	<xs:enumeration value="Stage IA" />
			458	<xs:enumeration value="Stage IB" />
			459	<xs:enumeration value="Stage II" />
			460	<xs:enumeration value="Stage IIA" />
			461	<xs:enumeration value="Stage IIB" />
			462	<xs:enumeration value="Stage IIC" />
			463	<xs:enumeration value="Stage III" />
			464	<xs:enumeration value="Stage IIIA" />
			465	<xs:enumeration value="Stage IIIB" />
			466	<xs:enumeration value="Stage IIIC" />
			467	<xs:enumeration value="Stage IV" />
			468	<xs:enumeration value="Stage IVA" />
			469	<xs:enumeration value="Stage IVB" />
			470	<xs:enumeration value="Stage IIA Cervix" />
			471	<xs:enumeration value="Stage II Cervix" />
			472	<xs:enumeration value="Stage IB2" />
			473	<xs:enumeration value="Stage IB1" />
			474	<xs:enumeration value="Stage IB Cervix" />
			475	<xs:enumeration value="Stage IA2" />
			476	<xs:enumeration value="Stage IA1" />
			477	<xs:enumeration value="Stage IVC" />
			478	<xs:enumeration value="Stage 0is" />
			479	<xs:enumeration value="Stage 0a" />
			480	<xs:attribute name="cde" type="xs:string" default="3203222" />
			481	<xs:attribute name="xsd_ver" type="xs:string" default="2.5" />
			482	<xs:attribute name="tier" type="xs:string" default="2" />
			483	</xs:restriction>
			484	</xs:simpleContent>
			485	</xs:complexType>
			486	</xs:element>

   
File: TCGA_BCR.SKCM_Clinical_FollowUp_v2.0.xsd  

1	<?xml version="1.0" encoding="utf-8" ?>	+-
3	<xs:schema elementFormDefault="qualified" version="2.5.0"	+-
4	xmlns:xs="http://www.w3.org/2001/XMLSchema"
5	xmlns:shared="http://tcga.nci/bcr/xml/clinical/shared/2.5"
6	xmlns:utility="http://tcga.nci/bcr/xml/utility/2.5"
7	xmlns:admin="http://tcga.nci/bcr/xml/administration/2.5"
8	xmlns:rad="http://tcga.nci/bcr/xml/clinical/radiation/2.5"
9	xmlns:skcm_shared="http://tcga.nci/bcr/xml/clinical/skcm/shared/2.5"
10	xmlns="http://tcga.nci/bcr/xml/clinical/skcm/followup/2.5/2.0"
11	targetNamespace="http://tcga.nci/bcr/xml/clinical/skcm/followup/2.5/2.0"
12	xmlns:jaxb="http://java.sun.com/xml/ns/jaxb" jaxb:version="1.0" >
14	<xs:import namespace="http://tcga.nci/bcr/xml/utility/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/utility/2.5/TCGA_BCR.Utility.xsd" />	+-
15	<xs:import namespace="http://tcga.nci/bcr/xml/administration/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/administration/2.5/TCGA_BCR.Administration.xsd" />
16	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/radiation/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/radiation/2.5/TCGA_BCR.Radiation.xsd" />
17	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/shared/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/shared/2.5/TCGA_BCR.Shared_Clinical_Elements.xsd" />
18	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/skcm/shared/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/skcm/shared/2.5/TCGA_BCR.SKCM_Clinical_Shared_Datatypes.xsd" />
19	<xs:annotation>
20	<xs:appinfo>
21	<jaxb:globalBindings generateIsSetMethod="true" />
22	<jaxb:schemaBindings>
23	<jaxb:package name="nci.tcga.bcr.xml.jaxb.clinical.skcm" />
24	</jaxb:schemaBindings>
25	</xs:appinfo>
26	</xs:annotation>
27	<xs:annotation>
28	<xs:documentation xml:lang="en">Schema to define the elements of the TCGA Clinical Data Follow-up Form within the SKCM study.</xs:documentation>
29	</xs:annotation>
30	<xs:element name="follow_up_v2.0">
31	<xs:complexType>
32	<xs:sequence>
33	<xs:element ref="shared:bcr_patient_barcode" />
34	<xs:element ref="shared:bcr_patient_uuid" />
35	<xs:element ref="shared:followup_case_report_form_submission_reason" />
36	<xs:element ref="shared:radiation_therapy" />
37	<xs:element ref="shared:targeted_molecular_therapy" />
38	<xs:element ref="shared:vital_status" />
40	<xs:choice>	+-
41	<xs:annotation><xs:documentation>
42	Data for the DATE_of_death elements are also asked on the
44	TCGA Clinical Data Form during initial enrollment within the THCA study.	+-
45	</xs:documentation></xs:annotation>
46	<xs:sequence>
47	<xs:element ref="shared:day_of_last_followup" />
48	<xs:element ref="shared:month_of_last_followup" />
49	<xs:element ref="shared:year_of_last_followup" />
50	</xs:sequence>
51	<xs:element ref="shared:days_to_last_followup" />
53	</xs:choice>	+-
55	<xs:choice>	+-
56	<xs:annotation><xs:documentation>
57	Data for the DATE_of_death elements are also asked on the
58	TCGA Clinical Data Form during initial enrollment within the THCA study.
59	</xs:documentation></xs:annotation>
60	<xs:sequence>
61	<xs:element ref="shared:day_of_death" />
62	<xs:element ref="shared:month_of_death" />
63	<xs:element ref="shared:year_of_death" />
64	</xs:sequence>
65	<xs:element ref="shared:days_to_death" />
66	</xs:choice>
67	<xs:element ref="shared:person_neoplasm_cancer_status" />
68	<xs:element ref="shared:new_tumor_event_after_initial_treatment" />
69	<xs:choice>
70	<xs:annotation><xs:documentation>
71	Data for the DATE_of_last_followup elements are also asked on the
72	TCGA Clinical Data Form during initial enrollment within the THCA study.
73	</xs:documentation></xs:annotation>
74	<xs:sequence>
75	<xs:element ref="shared:day_of_new_tumor_event_after_initial_treatment" />
76	<xs:element ref="shared:month_of_new_tumor_event_after_initial_treatment" />
77	<xs:element ref="shared:year_of_new_tumor_event_after_initial_treatment" />
78	</xs:sequence>
79	<xs:element ref="shared:days_to_new_tumor_event_after_initial_treatment" />
80	</xs:choice>
81	<xs:element ref="shared:new_neoplasm_event_type" />
82	<xs:element ref="skcm_shared:new_neoplasm_event_occurrence_anatomic_site" />
83	<xs:element ref="skcm_shared:new_neoplasm_occurrence_anatomic_site_text" />
85	<xs:element ref="shared:additional_surgery_locoregional_procedure" />	+-
86	<xs:element ref="shared:month_of_additional_surgery_metastatic_procedure" />
87	<xs:element ref="shared:day_of_additional_surgery_metastatic_procedure" />
88	<xs:element ref="shared:year_of_additional_surgery_metastatic_procedure" />
89	<xs:element ref="shared:additional_radiation_therapy" />
90	<xs:element ref="shared:additional_pharmaceutical_therapy" />
93	<xs:choice>	+-
94	<xs:annotation>
95	<xs:documentation>
96	Date the interviewer originally completed the corresponding TCGA Clinical Data Form.
97	If modifications are made after the form is marked complete, this date should not change.
98	</xs:documentation>
99	</xs:annotation>
100	<xs:sequence>
101	<xs:element ref="shared:day_of_form_completion" />
102	<xs:element ref="shared:month_of_form_completion" />
103	<xs:element ref="shared:year_of_form_completion" />
104	</xs:sequence>
105	<xs:element ref="shared:days_to_form_completion" />
106	</xs:choice>
107	</xs:sequence>
108	<xs:attribute name="version" type="xs:string" default="2.0" use="optional"/>
109	</xs:complexType>
110	</xs:element>
113	</xs:schema>	+-

   
File: TCGA_BCR.SKCM_Clinical_Shared_Datatypes.xsd  

1	<?xml version="1.0" encoding="utf-8" ?>	+-
4	<xs:schema elementFormDefault="qualified" version="2.5.0"	+-
5	xmlns:xs="http://www.w3.org/2001/XMLSchema"
6	xmlns:utility="http://tcga.nci/bcr/xml/utility/2.5"
7	xmlns="http://tcga.nci/bcr/xml/clinical/skcm/shared/2.5"
8	targetNamespace="http://tcga.nci/bcr/xml/clinical/skcm/shared/2.5">
10	<xs:import namespace="http://tcga.nci/bcr/xml/utility/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/utility/2.5/TCGA_BCR.Utility.xsd" />	+-
12	<xs:element name="new_neoplasm_event_occurrence_anatomic_site" nillable="true">	+-
13	<xs:complexType mixed="true">
14	<xs:simpleContent>
15	<xs:restriction base="utility:clinical_res_attributes">
16	<xs:enumeration value="" />
17	<xs:enumeration value="Anus" />
18	<xs:enumeration value="Bladder" />
19	<xs:enumeration value="Bone" />
20	<xs:enumeration value="Brain" />
21	<xs:enumeration value="Cervical Lymph Node" />
22	<xs:enumeration value="Cervix" />
23	<xs:enumeration value="Distant Metastasis " />
24	<xs:enumeration value="Head &amp; Neck" />
25	<xs:enumeration value="Hypopharynx" />
26	<xs:enumeration value="Larynx" />
27	<xs:enumeration value="Liver" />
28	<xs:enumeration value="Lung" />
29	<xs:enumeration value="Lymph Node Only" />
30	<xs:enumeration value="Non-regional / Distant Lymph Nodes" />
31	<xs:enumeration value="Not Applicable" />
32	<xs:enumeration value="Oral Cavity" />
33	<xs:enumeration value="Oropharynx" />
34	<xs:enumeration value="Other, specify" />
35	<xs:enumeration value="Peritoneal Surfaces" />
36	<xs:enumeration value="Renal Pelvis" />
37	<xs:enumeration value="Ureter" />
38	<xs:enumeration value="Urethra" />
39	<xs:enumeration value="Vulva" />
40	<xs:attribute name="cde" type="xs:string" default="3108271" />
41	<xs:attribute name="xsd_ver" type="xs:string" default="2.5" />
42	<xs:attribute name="tier" type="xs:string" default="2" />
43	</xs:restriction>
44	</xs:simpleContent>
45	</xs:complexType>
46	</xs:element>
48	<xs:element name="new_neoplasm_occurrence_anatomic_site_text" nillable="true">	+-
49	<xs:complexType>
50	<xs:simpleContent>
51	<xs:extension base="xs:string">
52	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
53	<xs:attribute name="cde" type="xs:string" default="3128033" />
54	<xs:attribute name="xsd_ver" type="xs:string" default="2.5" />
55	<xs:attribute name="tier" type="xs:string" default="2" />
56	</xs:extension>
57	</xs:simpleContent>
58	</xs:complexType>
59	</xs:element>
60	</xs:schema>

   
File: TCGA_BCR.STAD_Clinical.xsd  

3	<xs:schema xmlns:xs="http://www.w3.org/2001/XMLSchema" xmlns:utility="http://tcga.nci/bcr/xml/utility/2.5" xmlns:admin="http://tcga.nci/bcr/xml/administration/2.5" xmlns:shared="http://tcga.nci/bcr/xml/clinical/shared/2.5" xmlns:rad="http://tcga.nci/bcr/xml/clinical/radiation/2.5" xmlns:rx="http://tcga.nci/bcr/xml/clinical/pharmaceutical/2.5" xmlns:follow_up_v1.0="http://tcga.nci/bcr/xml/clinical/stad/followup/2.5/1.0" xmlns:cqcf="http://tcga.nci/bcr/xml/clinical/cqcf/2.5" xmlns="http://tcga.nci/bcr/xml/clinical/stad/2.5" xmlns:jaxb="http://java.sun.com/xml/ns/jaxb" targetNamespace="http://tcga.nci/bcr/xml/clinical/stad/2.5" elementFormDefault="qualified" version="2.5.0" jaxb:version="1.0">	<>	3
			4	<xs:schema elementFormDefault="qualified" version="2.4.4"
			5	xmlns:xs="http://www.w3.org/2001/XMLSchema"
			6	xmlns:utility="http://tcga.nci/bcr/xml/utility/2.4"
			7	xmlns:admin="http://tcga.nci/bcr/xml/administration/2.4"
			8	xmlns:shared="http://tcga.nci/bcr/xml/clinical/shared/2.4"
			9	xmlns:rad="http://tcga.nci/bcr/xml/clinical/radiation/2.4"
			10	xmlns:rx="http://tcga.nci/bcr/xml/clinical/pharmaceutical/2.4"
			11	xmlns="http://tcga.nci/bcr/xml/clinical/stad/2.4"
			12	targetNamespace="http://tcga.nci/bcr/xml/clinical/stad/2.4"
			13	xmlns:jaxb="http://java.sun.com/xml/ns/jaxb" jaxb:version="1.0">
15	<xs:import namespace="http://tcga.nci/bcr/xml/utility/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/utility/2.5/TCGA_BCR.Utility.xsd"/>	<>	28	<xs:import namespace="http://tcga.nci/bcr/xml/utility/2.4" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/utility/2.4/TCGA_BCR.Utility.xsd" />
16	<xs:import namespace="http://tcga.nci/bcr/xml/administration/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/administration/2.5/TCGA_BCR.Administration.xsd"/>		29	<xs:import namespace="http://tcga.nci/bcr/xml/administration/2.4" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/administration/2.4/TCGA_BCR.Administration.xsd" />
17	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/shared/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/shared/2.5/TCGA_BCR.Shared_Clinical_Elements.xsd"/>		30	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/shared/2.4" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/shared/2.4/TCGA_BCR.Shared_Clinical_Elements.xsd" />
18	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/radiation/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/radiation/2.5/TCGA_BCR.Radiation.xsd"/>		31	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/radiation/2.4" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/radiation/2.4/TCGA_BCR.Radiation.xsd" />
19	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/pharmaceutical/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/pharmaceutical/2.5/TCGA_BCR.Pharmaceutical.xsd"/>		32	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/pharmaceutical/2.4" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/pharmaceutical/2.4/TCGA_BCR.Pharmaceutical.xsd" />
20	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/stad/followup/2.5/1.0" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/stad/followup/2.5/TCGA_BCR.STAD_Clinical_FollowUp_v1.0.xsd"/>		33
21	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/cqcf/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/cqcf/2.5/TCGA_BCR.CQCF.xsd"/>
28	<xs:attribute name="schemaVersion" type="xs:decimal" use="required" fixed="2.5"/>	<>	41	<xs:attribute name="schemaVersion" type="xs:decimal" use="required" fixed="2.4"/>
96	<xs:element ref="shared:anatomic_organ_subdivision"/>	<>	124	<xs:element ref="anatomic_organ_subdivision" />
97	<xs:element ref="shared:primary_lymph_node_presentation_assessment"/>
98	<xs:element ref="shared:lymph_node_examined_count"/>		125	<xs:element ref="lymphnodes_examined" />
99	<xs:element ref="shared:number_of_lymphnodes_positive_by_he"/>		126	<xs:element ref="number_of_lymphnodes_examined" />
100	<xs:element ref="shared:number_of_lymphnodes_positive_by_ihc"/>		127	<xs:element ref="number_of_lymphnodes_positive_by_he" />
104	<xs:element ref="shared:neoplasm_histologic_grade"/>	<>	131	<xs:element ref="tumor_grade" />
107	<xs:element ref="shared:residual_tumor"/>	<>	134	<xs:element ref="residual_tumor" />
			135	<xs:element ref="ajcc_handbook_addition" />
117	<xs:element ref="clinical_cqcf"/>	+-
118	<xs:element name="follow_ups">
119	<xs:annotation>
120	<xs:documentation>We are using namespaces and version numbers to distinguish one version of followup from another.</xs:documentation>
121	</xs:annotation>
122	<xs:complexType>
123	<xs:sequence>
124	<xs:element ref="follow_up_v1.0:follow_up_v1.0" minOccurs="0" maxOccurs="unbounded"/>
128	</xs:sequence>	<>	148
129	</xs:complexType>
130	</xs:element>
131	<xs:element name="clinical_cqcf">
132	<xs:complexType>
133	<xs:sequence>
134	<xs:element ref="cqcf:frozen_specimen_anatomic_site"/>
135	<xs:element ref="cqcf:history_of_prior_malignancy"/>
136	<xs:element ref="cqcf:history_of_neoadjuvant_treatment"/>
137	<xs:element ref="cqcf:consent_or_death_status"/>
138	<xs:choice>
139	<xs:choice>
140	<xs:sequence>
141	<xs:element ref="cqcf:day_of_consent"/>
142	<xs:element ref="cqcf:month_of_consent"/>
143	<xs:element ref="cqcf:year_of_consent"/>
144	</xs:sequence>
145	<xs:element ref="cqcf:days_to_consent"/>
146	</xs:choice>
147	<xs:choice>
148	<xs:sequence>
149	<xs:element ref="shared:day_of_death"/>
150	<xs:element ref="shared:month_of_death"/>
151	<xs:element ref="shared:year_of_death"/>
152	</xs:sequence>
153	<xs:element ref="shared:days_to_death"/>
154	</xs:choice>
155	</xs:choice>
156	<xs:element ref="cqcf:diagnosis_subtype"/>
157	<xs:element ref="shared:prior_diagnosis"/>
158	<xs:element ref="cqcf:normal_tissue_anatomic_site"/>
159	<xs:element ref="cqcf:normal_tissue_proximity"/>
160	<xs:element ref="cqcf:tumor_type"/>
161	<xs:element ref="cqcf:histological_subtype" minOccurs="0"/>
162	<xs:element ref="cqcf:other_anatomic_site" minOccurs="0"/>
163	<xs:element ref="cqcf:country"/>
164	</xs:sequence>
165	</xs:complexType>
166	</xs:element>
		-+	201	<xs:element name="tumor_grade" nillable="true">
			202	<xs:complexType>
			203	<xs:simpleContent>
			204	<xs:restriction base="utility:clinical_res_attributes">
			205	<xs:enumeration value="" />
			206	<xs:enumeration value="GX" />
			207	<xs:enumeration value="G1" />
			208	<xs:enumeration value="G2" />
			209	<xs:enumeration value="G3" />
			210	<xs:attribute name="cde" type="xs:string" default="2785839" />
			211	<xs:attribute name="xsd_ver" type="xs:string" default="1.11" />
			212	<xs:attribute name="tier" type="xs:string" default="1" />
			213	</xs:restriction>
			214	</xs:simpleContent>
			215	</xs:complexType>
			216	</xs:element>
		-+	218	<xs:element name="residual_tumor" nillable="true">
			219	<xs:complexType>
			220	<xs:simpleContent>
			221	<xs:restriction base="utility:clinical_res_attributes">
			222	<xs:enumeration value="" />
			223	<xs:enumeration value="RX" />
			224	<xs:enumeration value="R0" />
			225	<xs:enumeration value="R1" />
			226	<xs:enumeration value="R2" />
			227	<xs:attribute name="cde" type="xs:string" default="2608702" />
			228	<xs:attribute name="xsd_ver" type="xs:string" default="2.4" />
			229	<xs:attribute name="tier" type="xs:string" default="2" />
			230	</xs:restriction>
			231	</xs:simpleContent>
			232	</xs:complexType>
			233	</xs:element>
		-+	235	<xs:element name="ajcc_handbook_addition" nillable="true">
			236	<xs:complexType>
			237	<xs:simpleContent>
			238	<xs:restriction base="utility:clinical_res_attributes">
			239	<xs:enumeration value="" />
			240	<xs:enumeration value="First Edition" />
			241	<xs:enumeration value="Second Edition" />
			242	<xs:enumeration value="Third Edition" />
			243	<xs:enumeration value="Fourth Edition" />
			244	<xs:enumeration value="Fifth Edition" />
			245	<xs:enumeration value="Sixth Edition" />
			246	<xs:enumeration value="Seventh Edition" />
			247	<xs:attribute name="cde" type="xs:string" default="2722309" />
			248	<xs:attribute name="xsd_ver" type="xs:string" default="2.4" />
			249	<xs:attribute name="tier" type="xs:string" default="1" />
			250	</xs:restriction>
			251	</xs:simpleContent>
			252	</xs:complexType>
			253	</xs:element>
219	<xs:attribute name="cde" type="xs:string" default=""/>	<>	259	<xs:attribute name="cde" type="xs:string" default="3203072" />
		-+	331	<xs:element name="lymphnodes_examined" nillable="true">
			332	<xs:complexType>
			333	<xs:simpleContent>
			334	<xs:extension base="utility:yes_or_no">
			335	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			336	<xs:attribute name="cde" type="xs:string" default="2200396" />
			337	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
			338	<xs:attribute name="tier" type="xs:string" default="2" />
			339	</xs:extension>
			340	</xs:simpleContent>
			341	</xs:complexType>
			342	</xs:element>
		-+	344	<xs:element name="number_of_lymphnodes_positive_by_he" nillable="true">
			345	<xs:complexType mixed="true">
			346	<xs:simpleContent>
			347	<xs:restriction base="utility:clinical_res_attributes">
			348	<xs:attribute name="cde" type="xs:string" default="3086388" />
			349	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
			350	<xs:attribute name="tier" type="xs:string" default="2" />
			351	</xs:restriction>
			352	</xs:simpleContent>
			353	</xs:complexType>
			354	</xs:element>
		-+	356	<xs:element name="anatomic_organ_subdivision" nillable="true">
			357	<xs:complexType mixed="true">
			358	<xs:simpleContent>
			359	<xs:restriction base="utility:clinical_res_attributes">
			360	<xs:enumeration value="" />
			361	<xs:enumeration value="Gastrostroesophageal Junction" />
			362	<xs:enumeration value="Cardia/Proximal" />
			363	<xs:enumeration value="Fundus/Body" />
			364	<xs:enumeration value="Antrum/Distal" />
			365	<xs:attribute name="cde" type="xs:string" default="2008006" />
			366	<xs:attribute name="xsd_ver" type="xs:string" default="2.4" />
			367	<xs:attribute name="tier" type="xs:string" default="2" />
			368	</xs:restriction>
			369	</xs:simpleContent>
			370	</xs:complexType>
			371	</xs:element>
		-+	391	<xs:enumeration value="Stage IA" />
			392	<xs:enumeration value="Stage IB" />
		-+	394	<xs:enumeration value="Stage IIA" />
			395	<xs:enumeration value="Stage IIB" />
304	<xs:enumeration value="Stage IVA"/>	<>	397	<xs:enumeration value="Stage IIIA" />
305	<xs:enumeration value="Stage IVB"/>		398	<xs:enumeration value="Stage IIIB" />
306	<xs:enumeration value="Stage IVC"/>		399	<xs:enumeration value="Stage IIIC" />
315	<xs:element name="lymphnode_pathologic_spread" nillable="true">	<>	408
316	<xs:complexType>
317	<xs:simpleContent>
318	<xs:restriction base="utility:clinical_res_attributes">
319	<xs:enumeration value=""/>
320	<xs:enumeration value="NX"/>
321	<xs:enumeration value="N0"/>
322	<xs:enumeration value="N1"/>
323	<xs:enumeration value="N2"/>
324	<xs:enumeration value="N2a"/>
325	<xs:enumeration value="N2b"/>
326	<xs:enumeration value="N2c"/>
327	<xs:enumeration value="N3"/>
328	<xs:attribute name="cde" type="xs:string" default="3065858"/>
329	<xs:attribute name="xsd_ver" type="xs:string" default="2.1"/>
330	<xs:attribute name="tier" type="xs:string" default="1"/>
331	</xs:restriction>
332	</xs:simpleContent>
333	</xs:complexType>
334	</xs:element>
335	<xs:element name="distant_metastasis_pathologic_spread" nillable="true">
336	<xs:complexType>
337	<xs:simpleContent>
338	<xs:restriction base="utility:clinical_res_attributes">
339	<xs:enumeration value=""/>
340	<xs:enumeration value="M0"/>
341	<xs:enumeration value="M1"/>
342	<xs:enumeration value="MX"/>
343	<xs:attribute name="cde" type="xs:string" default="3045439"/>
344	<xs:attribute name="xsd_ver" type="xs:string" default="2.4"/>
345	<xs:attribute name="tier" type="xs:string" default="1"/>
346	</xs:restriction>
347	</xs:simpleContent>
348	</xs:complexType>
349	</xs:element>
		-+	434	<xs:element name="lymphnode_pathologic_spread" nillable="true">
			435	<xs:complexType>
			436	<xs:simpleContent>
			437	<xs:restriction base="utility:clinical_res_attributes">
			438	<xs:enumeration value="" />
			439	<xs:enumeration value="NX" />
			440	<xs:enumeration value="N0" />
			441	<xs:enumeration value="N1" />
			442	<xs:enumeration value="N2" />
			443	<xs:enumeration value="N3" />
			444	<xs:enumeration value="N3a" />
			445	<xs:enumeration value="N3b" />
			446	<xs:attribute name="cde" type="xs:string" default="3065858" />
			447	<xs:attribute name="xsd_ver" type="xs:string" default="2.1" />
			448	<xs:attribute name="tier" type="xs:string" default="1" />
			449	</xs:restriction>
			450	</xs:simpleContent>
			451	</xs:complexType>
			452	</xs:element>
		-+	454	<xs:element name="distant_metastasis_pathologic_spread" nillable="true">
			455	<xs:complexType>
			456	<xs:simpleContent>
			457	<xs:restriction base="utility:clinical_res_attributes">
			458	<xs:enumeration value="" />
			459	<xs:enumeration value="MX" />
			460	<xs:enumeration value="M0" />
			461	<xs:enumeration value="M1" />
			462	<xs:attribute name="cde" type="xs:string" default="3045439" />
			463	<xs:attribute name="xsd_ver" type="xs:string" default="2.1" />
			464	<xs:attribute name="tier" type="xs:string" default="1" />
			465	</xs:restriction>
			466	</xs:simpleContent>
			467	</xs:complexType>
			468	</xs:element>
		-+	470	<xs:element name="number_of_lymphnodes_examined" nillable="true">
			471	<xs:complexType mixed="true">
			472	<xs:simpleContent>
			473	<xs:restriction base="utility:clinical_res_attributes">
			474	<xs:attribute name="cde" type="xs:string" default="3" />
			475	<xs:attribute name="xsd_ver" type="xs:string" default="2.1" />
			476	<xs:attribute name="tier" type="xs:string" default="2" />
			477	</xs:restriction>
			478	</xs:simpleContent>
			479	</xs:complexType>
			480	</xs:element>

   
File: TCGA_BCR.STAD_Clinical_FollowUp_v1.0.xsd  

1	<?xml version="1.0" encoding="utf-8" ?>	+-
4	<xs:schema elementFormDefault="qualified" version="2.5.0"	+-
5	xmlns:xs="http://www.w3.org/2001/XMLSchema"
6	xmlns:shared="http://tcga.nci/bcr/xml/clinical/shared/2.5"
7	xmlns:utility="http://tcga.nci/bcr/xml/utility/2.5"
8	xmlns:admin="http://tcga.nci/bcr/xml/administration/2.5"
9	xmlns="http://tcga.nci/bcr/xml/clinical/stad/followup/2.5/1.0"
10	targetNamespace="http://tcga.nci/bcr/xml/clinical/stad/followup/2.5/1.0"
11	xmlns:jaxb="http://java.sun.com/xml/ns/jaxb" jaxb:version="1.0" >
13	<xs:import schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/utility/2.5/TCGA_BCR.Utility.xsd" namespace="http://tcga.nci/bcr/xml/utility/2.5" />	+-
14	<xs:import schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/administration/2.5/TCGA_BCR.Administration.xsd" namespace="http://tcga.nci/bcr/xml/administration/2.5" />
15	<xs:import schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/shared/2.5/TCGA_BCR.Shared_Clinical_Elements.xsd" namespace="http://tcga.nci/bcr/xml/clinical/shared/2.5" />
17	<xs:annotation>	+-
18	<xs:appinfo>
19	<jaxb:globalBindings generateIsSetMethod="true" />
20	<jaxb:schemaBindings>
21	<jaxb:package name="nci.tcga.bcr.xml.jaxb.clinical.stad" />
22	</jaxb:schemaBindings>
23	</xs:appinfo>
24	</xs:annotation>
26	<xs:annotation>	+-
27	<xs:documentation xml:lang="en">Schema to define the elements of the TCGA Clinical Data Follow-up Form within the STAD study.</xs:documentation>
28	</xs:annotation>
30	<xs:element name="follow_up_v1.0">	+-
31	<xs:complexType>
32	<xs:sequence>
33	<xs:element ref="shared:bcr_patient_barcode" />
34	<xs:element ref="shared:bcr_patient_uuid" />
35	<xs:element ref="shared:vital_status" />
36	<xs:choice>
37	<xs:sequence>
38	<xs:element ref="shared:day_of_last_followup" />
39	<xs:element ref="shared:month_of_last_followup" />
40	<xs:element ref="shared:year_of_last_followup" />
41	</xs:sequence>
42	<xs:element ref="shared:days_to_last_followup" />
43	</xs:choice>
44	<xs:choice>
45	<xs:sequence>
46	<xs:element ref="shared:day_of_death" />
47	<xs:element ref="shared:month_of_death" />
48	<xs:element ref="shared:year_of_death" />
49	</xs:sequence>
50	<xs:element ref="shared:days_to_death" />
51	</xs:choice>
52	<xs:element ref="new_tumor_event_after_initial_treatment" />
53	<xs:choice>
54	<xs:sequence>
55	<xs:element ref="shared:day_of_new_tumor_event_after_initial_treatment" />
56	<xs:element ref="shared:month_of_new_tumor_event_after_initial_treatment" />
57	<xs:element ref="shared:year_of_new_tumor_event_after_initial_treatment" />
58	</xs:sequence>
59	<xs:element ref="shared:days_to_new_tumor_event_after_initial_treatment" />
60	</xs:choice>
61	<xs:element ref="shared:additional_surgery_locoregional_procedure" />
62	<xs:choice>
63	<xs:sequence>
64	<xs:element ref="shared:day_of_additional_surgery_locoregional_procedure" />
65	<xs:element ref="shared:month_of_additional_surgery_locoregional_procedure" />
66	<xs:element ref="shared:year_of_additional_surgery_locoregional_procedure" />
67	</xs:sequence>
68	<xs:element ref="shared:days_to_additional_surgery_locoregional_procedure" />
69	</xs:choice>
70	<xs:element ref="shared:person_neoplasm_cancer_status" />
71	<xs:element ref="shared:additional_radiation_therapy" />
72	<xs:element ref="shared:radiation_therapy" />
73	<xs:element ref="shared:targeted_molecular_therapy" />
74	<xs:element ref="shared:additional_pharmaceutical_therapy" />
75	<xs:element ref="shared:additional_surgery_metastatic_procedure" />
76	<xs:choice>
77	<xs:sequence>
78	<xs:element ref="shared:day_of_additional_surgery_metastatic_procedure" />
79	<xs:element ref="shared:month_of_additional_surgery_metastatic_procedure" />
80	<xs:element ref="shared:year_of_additional_surgery_metastatic_procedure" />
81	</xs:sequence>
82	<xs:element ref="shared:days_to_additional_surgery_metastatic_procedure" />
83	</xs:choice>
84	<xs:choice>
85	<xs:sequence>
86	<xs:element ref="shared:day_of_form_completion" />
87	<xs:element ref="shared:month_of_form_completion" />
88	<xs:element ref="shared:year_of_form_completion" />
89	</xs:sequence>
90	<xs:element ref="shared:days_to_form_completion" />
91	</xs:choice>
93	<xs:element ref="shared:followup_case_report_form_submission_reason" />	+-
95	<xs:element ref="shared:progression_determined_by" />	+-
96	<xs:element ref="new_neoplasm_event_occurrence_anatomic_site" />
97	<xs:element ref="new_neoplasm_occurrence_anatomic_site_text" />
98	<xs:element ref="primary_therapy_outcome_success" />
99	<xs:element ref="followup_treatment_success" />
100	<xs:element ref="patient_death_reason" />
101	<xs:element ref="shared:new_neoplasm_event_type" />
102	<xs:element ref="shared:followup_met_assessment_outcome_success_margin_status" />
103	</xs:sequence>
105	<xs:attribute name="version" type="xs:string" default="1.0" use="optional"/>	+-
106	</xs:complexType>
107	</xs:element>
109	<xs:element name="patient_death_reason" nillable="true">	+-
110	<xs:complexType mixed="true">
111	<xs:simpleContent>
112	<xs:restriction base="utility:clinical_res_attributes">
113	<xs:enumeration value="" />
114	<xs:enumeration value="Stomach Cancer" />
115	<xs:enumeration value="Other Malignancy (not stomach cancer related)" />
116	<xs:enumeration value="Other Non-Malignant Disease" />
117	<xs:enumeration value="Unknown cause of death" />
118	<xs:attribute name="cde" type="xs:string" default="2554674" />
119	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
120	<xs:attribute name="tier" type="xs:string" default="2" />
121	</xs:restriction>
122	</xs:simpleContent>
123	</xs:complexType>
124	</xs:element>
126	<xs:element name="new_tumor_event_after_initial_treatment" nillable="true">	+-
127	<xs:complexType>
128	<xs:simpleContent>
129	<xs:extension base="utility:yes_or_no">
130	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
131	<xs:attribute name="cde" type="xs:string" default="3121376" />
132	<xs:attribute name="xsd_ver" type="xs:string" default="2.5" />
133	<xs:attribute name="tier" type="xs:string" default="1" />
134	</xs:extension>
135	</xs:simpleContent>
136	</xs:complexType>
137	</xs:element>
139	<xs:element name="new_neoplasm_event_occurrence_anatomic_site" nillable="true">	+-
140	<xs:complexType mixed="true">
141	<xs:simpleContent>
142	<xs:restriction base="utility:clinical_res_attributes">
143	<xs:enumeration value="" />
144	<xs:enumeration value="Anus" />
145	<xs:enumeration value="Bladder" />
146	<xs:enumeration value="Bone" />
147	<xs:enumeration value="Brain" />
148	<xs:enumeration value="Cervical Lymph Node" />
149	<xs:enumeration value="Cervix" />
150	<xs:enumeration value="Distant Metastasis " />
151	<xs:enumeration value="Head &amp; Neck" />
152	<xs:enumeration value="Hypopharynx" />
153	<xs:enumeration value="Larynx" />
154	<xs:enumeration value="Liver" />
155	<xs:enumeration value="Lung" />
156	<xs:enumeration value="Lymph Node Only" />
157	<xs:enumeration value="Non-regional / Distant Lymph Nodes" />
158	<xs:enumeration value="Not Applicable" />
159	<xs:enumeration value="Oral Cavity" />
160	<xs:enumeration value="Oropharynx" />
161	<xs:enumeration value="Other, specify" />
162	<xs:enumeration value="Peritoneal Surfaces" />
163	<xs:enumeration value="Renal Pelvis" />
164	<xs:enumeration value="Ureter" />
165	<xs:enumeration value="Urethra" />
166	<xs:enumeration value="Vulva" />
167	<xs:attribute name="cde" type="xs:string" default="3108271" />
168	<xs:attribute name="xsd_ver" type="xs:string" default="2.5" />
169	<xs:attribute name="tier" type="xs:string" default="2" />
170	</xs:restriction>
171	</xs:simpleContent>
172	</xs:complexType>
173	</xs:element>
175	<xs:element name="new_neoplasm_occurrence_anatomic_site_text" nillable="true">	+-
176	<xs:complexType>
177	<xs:simpleContent>
178	<xs:extension base="xs:string">
179	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
180	<xs:attribute name="cde" type="xs:string" default="3128033" />
181	<xs:attribute name="xsd_ver" type="xs:string" default="2.5" />
182	<xs:attribute name="tier" type="xs:string" default="2" />
183	</xs:extension>
184	</xs:simpleContent>
185	</xs:complexType>
186	</xs:element>
188	<xs:element name="followup_treatment_success" nillable="true">	+-
189	<xs:complexType>
190	<xs:simpleContent>
191	<xs:restriction base="utility:clinical_res_attributes">
192	<xs:enumeration value="" />
193	<xs:enumeration value="Complete Remission/Response" />
194	<xs:enumeration value="Not Applicable" />
195	<xs:enumeration value="Partial Remission/Response" />
196	<xs:enumeration value="Persistent Disease" />
197	<xs:enumeration value="Progressive Disease" />
198	<xs:enumeration value="Stable Disease" />
199	<xs:enumeration value="Unknown" />
200	<xs:attribute name="cde" type="xs:string" default="3104050" />
201	<xs:attribute name="xsd_ver" type="xs:string" default="2.5" />
202	<xs:attribute name="tier" type="xs:string" default="2" />
203	</xs:restriction>
204	</xs:simpleContent>
205	</xs:complexType>
206	</xs:element>
208	<xs:element name="primary_therapy_outcome_success" nillable="true">	+-
209	<xs:complexType>
210	<xs:simpleContent>
211	<xs:restriction base="utility:clinical_res_attributes">
212	<xs:enumeration value="" />
213	<xs:enumeration value="Progressive Disease" />
214	<xs:enumeration value="Stable Disease" />
215	<xs:enumeration value="Partial Response" />
216	<xs:enumeration value="Complete Response" />
217	<xs:attribute name="cde" type="xs:string" default="2786727" />
218	<xs:attribute name="xsd_ver" type="xs:string" default="1.11" />
219	<xs:attribute name="tier" type="xs:string" default="2" />
220	</xs:restriction>
221	</xs:simpleContent>
222	</xs:complexType>
223	</xs:element>
225	</xs:schema>	+-

   
File: TCGA_BCR.THCA_Clinical.xsd  

4	<xs:schema elementFormDefault="qualified" version="2.5.0"	<>	4	<xs:schema elementFormDefault="qualified" version="2.4.4"
6	xmlns:utility="http://tcga.nci/bcr/xml/utility/2.5"	<>	6	xmlns:utility="http://tcga.nci/bcr/xml/utility/2.4"
7	xmlns:admin="http://tcga.nci/bcr/xml/administration/2.5"		7	xmlns:admin="http://tcga.nci/bcr/xml/administration/2.4"
8	xmlns:shared="http://tcga.nci/bcr/xml/clinical/shared/2.5"		8	xmlns:shared="http://tcga.nci/bcr/xml/clinical/shared/2.4"
9	xmlns:rad="http://tcga.nci/bcr/xml/clinical/radiation/2.5"		9	xmlns:rad="http://tcga.nci/bcr/xml/clinical/radiation/2.4"
10	xmlns:rx="http://tcga.nci/bcr/xml/clinical/pharmaceutical/2.5"		10	xmlns:rx="http://tcga.nci/bcr/xml/clinical/pharmaceutical/2.4"
11	xmlns:cqcf="http://tcga.nci/bcr/xml/clinical/cqcf/2.5"
12	xmlns:cesc_shared="http://tcga.nci/bcr/xml/clinical/thca/shared/2.5"
13	xmlns:follow_up_v2.0="http://tcga.nci/bcr/xml/clinical/thca/followup/2.5/2.0"
14	xmlns="http://tcga.nci/bcr/xml/clinical/thca/2.5"		11	xmlns="http://tcga.nci/bcr/xml/clinical/thca/2.4"
15	targetNamespace="http://tcga.nci/bcr/xml/clinical/thca/2.5"		12	targetNamespace="http://tcga.nci/bcr/xml/clinical/thca/2.4"
31	<xs:import namespace="http://tcga.nci/bcr/xml/utility/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/utility/2.5/TCGA_BCR.Utility.xsd" />	<>	28	<xs:import namespace="http://tcga.nci/bcr/xml/utility/2.4" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/utility/2.4/TCGA_BCR.Utility.xsd" />
32	<xs:import namespace="http://tcga.nci/bcr/xml/administration/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/administration/2.5/TCGA_BCR.Administration.xsd" />		29	<xs:import namespace="http://tcga.nci/bcr/xml/administration/2.4" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/administration/2.4/TCGA_BCR.Administration.xsd" />
33	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/shared/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/shared/2.5/TCGA_BCR.Shared_Clinical_Elements.xsd" />		30	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/shared/2.4" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/shared/2.4/TCGA_BCR.Shared_Clinical_Elements.xsd" />
34	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/radiation/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/radiation/2.5/TCGA_BCR.Radiation.xsd" />		31	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/radiation/2.4" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/radiation/2.4/TCGA_BCR.Radiation.xsd" />
35	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/pharmaceutical/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/pharmaceutical/2.5/TCGA_BCR.Pharmaceutical.xsd" />		32	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/pharmaceutical/2.4" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/pharmaceutical/2.4/TCGA_BCR.Pharmaceutical.xsd" />
36	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/cqcf/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/cqcf/2.5/TCGA_BCR.CQCF.xsd" />
37	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/thca/shared/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/thca/shared/2.5/TCGA_BCR.THCA_Clinical_Shared_Datatypes.xsd" />
38	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/thca/followup/2.5/2.0" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/thca/followup/2.5/TCGA_BCR.THCA_Clinical_FollowUp_v2.0.xsd" />
54	<xs:element ref="shared:tissue_source_site" />	<>	48	<xs:choice>
			49	<xs:sequence>
55	<xs:element ref="shared:patient_id" />		50	<xs:element ref="shared:day_of_form_completion" />
56	<xs:element ref="shared:bcr_patient_barcode" />
57	<xs:element ref="shared:bcr_patient_uuid" />		51	<xs:element ref="shared:month_of_form_completion" />
58	<xs:element ref="shared:informed_consent_verified" />		52	<xs:element ref="shared:year_of_form_completion" />
59	<xs:element ref="shared:icd_o_3_site" />		53	</xs:sequence>
60	<xs:element ref="shared:icd_o_3_histology" />		54	<xs:element ref="shared:days_to_form_completion" />
61	<xs:element ref="shared:icd_10" />		55	</xs:choice>
105	<xs:element ref="histological_type" />	<>	100	<xs:element ref="neoplasm_histologic_type_name" />
106	<xs:element ref="shared:tumor_other_histologic_subtype_descriptive_text" />		101	<xs:element ref="tumor_other_histologic_subtype_descriptive_text" />
109	<xs:element ref="neoplasm_dimension" />	<>	104	<xs:element ref="neoplasm_excision_timepoint_pathologic_three_dimensional_size_text" />
125	<xs:element ref="shared:primary_lymph_node_presentation_assessment" />	<>	120	<xs:element ref="primary_lymph_node_presentation_assessment_ind" />
126	<xs:element ref="shared:lymph_node_examined_count" />		121	<xs:element ref="lymph_node_examined_count" />
127	<xs:element ref="shared:number_of_lymphnodes_positive_by_he" />		122	<xs:element ref="positive_finding_lymph_node_hematoxylin_and_eosin_staining_microscopy_count" />
129	<xs:element ref="shared:residual_tumor" />	<>	124	<xs:element ref="surgical_margin_resection_status" />
130	<xs:element ref="shared:ajcc_cancer_staging_handbook_edition" />		125	<xs:element ref="american_joint_committee_on_cancer_publication_version_type" />
131	<xs:element ref="shared:ajcc_tumor_stage_code" />		126	<xs:element ref="american_joint_committee_on_cancer_tumor_stage_code" />
132	<xs:element ref="shared:ajcc_neoplasm_disease_lymph_node_stage" />		127	<xs:element ref="neoplasm_disease_lymph_node_stage_american_joint_committee_on_cancer_code" />
133	<xs:element ref="shared:ajcc_cancer_metastasis_stage_code" />		128	<xs:element ref="american_joint_committee_on_cancer_metastasis_stage_code" />
134	<xs:element ref="shared:ajcc_neoplasm_disease_stage" />		129	<xs:element ref="neoplasm_disease_stage_american_joint_committee_on_cancer_code" />
137	<xs:element ref="malignant_neoplasm_metastatic_involvement_site" />	<>	132	<xs:element ref="metastatic_neoplasm_confirmed_diagnosis_anatomic_site_name" />
138	<xs:element ref="other_metastatic_involvement_anatomic_site" />		133	<xs:element ref="malignant_neoplasm_metastatic_involvement_anatomic_site_text" />
146	<xs:choice>	+-
147	<xs:sequence>
148	<xs:element ref="shared:day_of_form_completion" />
149	<xs:element ref="shared:month_of_form_completion" />
150	<xs:element ref="shared:year_of_form_completion" />
151	</xs:sequence>
152	<xs:element ref="shared:days_to_form_completion" />
153	</xs:choice>
155	<xs:element ref="follow_ups" />	<>	142	<xs:element ref="shared:bcr_patient_barcode" />
156	<xs:element ref="rx:drugs" />		143	<xs:element ref="shared:tissue_source_site" />
157	<xs:element ref="rad:radiations" />		144	<xs:element ref="shared:patient_id" />
158	<xs:element ref="clinical_cqcf" />		145	<xs:element ref="shared:bcr_patient_uuid" />
159	</xs:sequence>
160	</xs:complexType>
161	</xs:element>
163	<xs:element name="follow_ups">	<>	146	<xs:element ref="shared:informed_consent_verified" />
164	<xs:annotation>
165	<xs:documentation xml:lang="en">We are using namespaces and version numbers to distinguish one version of followup from another.</xs:documentation>
166	</xs:annotation>
167	<xs:complexType>
168	<xs:sequence>
169	<xs:element ref="follow_up_v2.0:follow_up_v2.0" minOccurs="0" maxOccurs="unbounded" />
170	</xs:sequence>
171	</xs:complexType>
172	</xs:element>
174	<xs:element name="clinical_cqcf">	<>	147	<xs:element ref="shared:icd_o_3_site" />
175	<xs:complexType>
176	<xs:sequence>
177	<xs:element ref="shared:anatomic_organ_subdivision"/>		148	<xs:element ref="shared:icd_o_3_histology" />
178	<xs:element ref="cqcf:consent_or_death_status"/>		149	<xs:element ref="shared:icd_10" />
180	<xs:choice>	+-
181	<xs:choice>
182	<xs:sequence>
183	<xs:element ref="cqcf:day_of_consent"/>
184	<xs:element ref="cqcf:month_of_consent"/>
185	<xs:element ref="cqcf:year_of_consent"/>
186	</xs:sequence>
188	<xs:element ref="cqcf:days_to_consent"/>	+-
189	</xs:choice>
191	<xs:choice>	<>	152	<!--xs:element ref="follow_up_case_report_form_submission_reason" />
192	<xs:sequence>
193	<xs:element ref="shared:day_of_death"/>		153	<xs:element ref="shared:radiation_therapy" />
194	<xs:element ref="shared:month_of_death"/>		154	<xs:element ref="shared:additional_pharmaceutical_therapy" />
195	<xs:element ref="shared:year_of_death"/>	<>	160	<xs:element ref="radiation_therapy_administered_dose_text" />
196	</xs:sequence>		161	<xs:element ref="radiosensitizing_agent_administered_indicator" />
198	<xs:element ref="shared:days_to_death"/>	<>
199	</xs:choice>		165	<xs:choice>
200	</xs:choice>	<>	172	</xs:choice>
202	<xs:element ref="cqcf:diagnosis_subtype"/>	<>	174	<xs:element ref="new_neoplasm_confirmed_diagnosis_method_name" />
203	<xs:element ref="shared:prior_diagnosis"/>		175	<xs:element ref="histologic_disease_progression_present_indicator" />
204	<xs:element ref="cqcf:history_of_neoadjuvant_treatment"/>	<>	179	<xs:element ref="new_neoplasm_event_occurrence_anatomic_site" />
205	<xs:element ref="cqcf:normal_tissue_anatomic_site"/>		180	<xs:element ref="new_neoplasm_occurrence_anatomic_site_text" />
206	<xs:element ref="cqcf:normal_tissue_proximity"/>	<>	195	<xs:element ref="shared:additional_radiation_therapy" />
207	<xs:element ref="cqcf:tumor_focality"/>		196	<xs:element ref="shared:additional_radiation_therapy" /-->
208	<xs:element ref="cqcf:tumor_type"/>	<>	198	<xs:element ref="rx:drugs" />
209	<xs:element ref="cqcf:other_diagnosis"/>		199	<xs:element ref="rad:radiations" />
210	<xs:element ref="cqcf:histological_subtype" minOccurs="0"/>
211	<xs:element ref="cqcf:other_anatomic_site" minOccurs="0"/>
212	<xs:element ref="cqcf:country"/>
318	<xs:element name="histological_type" nillable="true">	<>	305	<xs:element name="neoplasm_histologic_type_name" nillable="true">
		-+	318	</xs:simpleContent>
			319	</xs:complexType>
			320	</xs:element>
		-+	322	<xs:element name="tumor_other_histologic_subtype_descriptive_text" nillable="true">
			323	<xs:complexType>
			324	<xs:simpleContent>
			325	<xs:extension base="xs:string">
			326	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			327	<xs:attribute name="cde" type="xs:string" default="3124492" />
			328	<xs:attribute name="xsd_ver" type="xs:string" default="2.4" />
			329	<xs:attribute name="tier" type="xs:string" default="2" />
			330	</xs:extension>
367	<xs:element name="neoplasm_dimension" nillable="true">	+-
368	<xs:complexType>
369	<xs:sequence >
370	<xs:element ref="neoplasm_length" minOccurs="1" maxOccurs="1" />
371	<xs:element ref="neoplasm_width" minOccurs="1" maxOccurs="1" />
372	<xs:element ref="neoplasm_depth" minOccurs="1" maxOccurs="1" />
373	</xs:sequence>
374	</xs:complexType>
375	</xs:element>
377	<xs:element name="neoplasm_length" nillable="true">	<>	367	<xs:element name="neoplasm_excision_timepoint_pathologic_three_dimensional_size_text" nillable="true">
380	<xs:extension base="utility:number_or_null">	<>	370	<xs:extension base="xs:string">
382	<xs:attribute name="cde" type="xs:string" default="2764966" />	<>	372	<xs:attribute name="cde" type="xs:string" default="3167398" />
383	<xs:attribute name="xsd_ver" type="xs:string" default="2.5" />		373	<xs:attribute name="xsd_ver" type="xs:string" default="2.4" />
384	<xs:attribute name="tier" type="xs:string" default="2" />
385	</xs:extension>
386	</xs:simpleContent>
387	</xs:complexType>
388	</xs:element>
389	<xs:element name="neoplasm_width" nillable="true">
390	<xs:complexType>
391	<xs:simpleContent>
392	<xs:extension base="utility:number_or_null">
393	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
394	<xs:attribute name="cde" type="xs:string" default="2764966" />
395	<xs:attribute name="xsd_ver" type="xs:string" default="2.5" />
396	<xs:attribute name="tier" type="xs:string" default="2" />
397	</xs:extension>
398	</xs:simpleContent>
399	</xs:complexType>
400	</xs:element>
401	<xs:element name="neoplasm_depth" nillable="true">
402	<xs:complexType>
403	<xs:simpleContent>
404	<xs:extension base="utility:number_or_null">
405	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
406	<xs:attribute name="cde" type="xs:string" default="2764966" />
407	<xs:attribute name="xsd_ver" type="xs:string" default="2.5" />
		-+	419	<xs:element name="primary_lymph_node_presentation_assessment_ind" nillable="true">
			420	<xs:complexType>
			421	<xs:simpleContent>
			422	<xs:extension base="utility:yes_or_no">
			423	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			424	<xs:attribute name="cde" type="xs:string" default="2200396" />
			425	<xs:attribute name="xsd_ver" type="xs:string" default="2.4" />
			426	<xs:attribute name="tier" type="xs:string" default="1" />
			427	</xs:extension>
			428	</xs:simpleContent>
			429	</xs:complexType>
			430	</xs:element>
		-+	432	<xs:element name="lymph_node_examined_count" nillable="true">
			433	<xs:complexType>
			434	<xs:simpleContent>
			435	<xs:extension base="xs:integer">
			436	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			437	<xs:attribute name="cde" type="xs:string" default="3" />
			438	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
			439	<xs:attribute name="tier" type="xs:string" default="2" />
			440	</xs:extension>
			441	</xs:simpleContent>
			442	</xs:complexType>
			443	</xs:element>
		-+	445	<xs:element name="positive_finding_lymph_node_hematoxylin_and_eosin_staining_microscopy_count" nillable="true">
			446	<xs:complexType>
			447	<xs:simpleContent>
			448	<xs:extension base="xs:integer">
			449	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			450	<xs:attribute name="cde" type="xs:string" default="3086388" />
			451	<xs:attribute name="xsd_ver" type="xs:string" default="2.2" />
			452	<xs:attribute name="tier" type="xs:string" default="2" />
			453	</xs:extension>
			454	</xs:simpleContent>
			455	</xs:complexType>
			456	</xs:element>
		-+	468	<xs:attribute name="xsd_ver" type="xs:string" default="2.4" />
			469	<xs:attribute name="tier" type="xs:string" default="2" />
			470	</xs:restriction>
			471	</xs:simpleContent>
			472	</xs:complexType>
			473	</xs:element>
		-+	475	<xs:element name="surgical_margin_resection_status" nillable="true">
			476	<xs:complexType mixed="true">
			477	<xs:simpleContent>
			478	<xs:restriction base="utility:clinical_res_attributes">
			479	<xs:enumeration value="" />
			480	<xs:enumeration value="RX" />
			481	<xs:enumeration value="R0" />
			482	<xs:enumeration value="R1" />
			483	<xs:enumeration value="R2" />
			484	<xs:attribute name="cde" type="xs:string" default="2608702" />
			485	<xs:attribute name="xsd_ver" type="xs:string" default="2.4" />
			486	<xs:attribute name="tier" type="xs:string" default="2" />
			487	</xs:restriction>
			488	</xs:simpleContent>
			489	</xs:complexType>
			490	</xs:element>
		-+	492	<xs:element name="american_joint_committee_on_cancer_publication_version_type" nillable="true">
			493	<xs:complexType mixed="true">
			494	<xs:simpleContent>
			495	<xs:restriction base="utility:clinical_res_attributes">
			496	<xs:enumeration value="" />
			497	<xs:enumeration value="1st" />
			498	<xs:enumeration value="2nd" />
			499	<xs:enumeration value="3rd" />
			500	<xs:enumeration value="4th" />
			501	<xs:enumeration value="5th" />
			502	<xs:enumeration value="6th" />
			503	<xs:enumeration value="7th" />
			504	<xs:attribute name="cde" type="xs:string" default="2722309" />
			505	<xs:attribute name="xsd_ver" type="xs:string" default="2.4" />
			506	<xs:attribute name="tier" type="xs:string" default="2" />
			507	</xs:restriction>
			508	</xs:simpleContent>
			509	</xs:complexType>
			510	</xs:element>
		-+	512	<xs:element name="american_joint_committee_on_cancer_tumor_stage_code" nillable="true">
			513	<xs:complexType mixed="true">
			514	<xs:simpleContent>
			515	<xs:restriction base="utility:clinical_res_attributes">
			516	<xs:enumeration value="" />
			517	<xs:enumeration value="TX" />
			518	<xs:enumeration value="T0" />
			519	<xs:enumeration value="T1" />
			520	<xs:enumeration value="T1a" />
			521	<xs:enumeration value="T1b" />
			522	<xs:enumeration value="T1c" />
			523	<xs:enumeration value="T2" />
			524	<xs:enumeration value="T2a" />
			525	<xs:enumeration value="T2b" />
			526	<xs:enumeration value="T3" />
			527	<xs:enumeration value="T3a" />
			528	<xs:enumeration value="T3b" />
			529	<xs:enumeration value="T4" />
			530	<xs:enumeration value="T4a" />
			531	<xs:enumeration value="T4b" />
			532	<xs:attribute name="cde" type="xs:string" default="3045435" />
			533	<xs:attribute name="xsd_ver" type="xs:string" default="2.4" />
			534	<xs:attribute name="tier" type="xs:string" default="2" />
			535	</xs:restriction>
			536	</xs:simpleContent>
			537	</xs:complexType>
			538	</xs:element>
		-+	540	<xs:element name="neoplasm_disease_lymph_node_stage_american_joint_committee_on_cancer_code" nillable="true">
			541	<xs:complexType mixed="true">
			542	<xs:simpleContent>
			543	<xs:restriction base="utility:clinical_res_attributes">
			544	<xs:enumeration value="" />
			545	<xs:enumeration value="NX" />
			546	<xs:enumeration value="N0" />
			547	<xs:enumeration value="N1" />
			548	<xs:enumeration value="N1a" />
			549	<xs:enumeration value="N1b" />
			550	<xs:enumeration value="N1c" />
			551	<xs:enumeration value="N2" />
			552	<xs:attribute name="cde" type="xs:string" default="3203106" />
			553	<xs:attribute name="xsd_ver" type="xs:string" default="2.4" />
			554	<xs:attribute name="tier" type="xs:string" default="2" />
			555	</xs:restriction>
			556	</xs:simpleContent>
			557	</xs:complexType>
			558	</xs:element>
		-+	560	<xs:element name="american_joint_committee_on_cancer_metastasis_stage_code" nillable="true">
			561	<xs:complexType mixed="true">
			562	<xs:simpleContent>
			563	<xs:restriction base="utility:clinical_res_attributes">
			564	<xs:enumeration value="" />
			565	<xs:enumeration value="MX" />
			566	<xs:enumeration value="M0" />
			567	<xs:enumeration value="M1" />
			568	<xs:attribute name="cde" type="xs:string" default="3045439" />
			569	<xs:attribute name="xsd_ver" type="xs:string" default="2.4" />
			570	<xs:attribute name="tier" type="xs:string" default="2" />
			571	</xs:restriction>
			572	</xs:simpleContent>
			573	</xs:complexType>
			574	</xs:element>
		-+	576	<xs:element name="neoplasm_disease_stage_american_joint_committee_on_cancer_code" nillable="true">
			577	<xs:complexType mixed="true">
			578	<xs:simpleContent>
			579	<xs:restriction base="utility:clinical_res_attributes">
			580	<xs:enumeration value="" />
			581	<xs:enumeration value="Stage I" />
			582	<xs:enumeration value="Stage II" />
			583	<xs:enumeration value="Stage III" />
			584	<xs:enumeration value="Stage IV" />
			585	<xs:enumeration value="Stage IVA" />
			586	<xs:enumeration value="Stage IVB" />
			587	<xs:enumeration value="Stage IVC" />
			588	<xs:attribute name="cde" type="xs:string" default="3203222" />
508	<xs:element name="malignant_neoplasm_metastatic_involvement_site" nillable="true">	<>	634	<xs:element name="metastatic_neoplasm_confirmed_diagnosis_anatomic_site_name" nillable="true">
516	<xs:attribute name="cde" type="xs:string" default="62835" />	<>	642	<xs:attribute name="cde" type="xs:string" default="2967298" />
517	<xs:attribute name="xsd_ver" type="xs:string" default="2.5" />		643	<xs:attribute name="xsd_ver" type="xs:string" default="2.4" />
524	<xs:element name="other_metastatic_involvement_anatomic_site" nillable="true">	<>	650	<xs:element name="malignant_neoplasm_metastatic_involvement_anatomic_site_text" nillable="true">
529	<xs:attribute name="cde" type="xs:string" default="3135371" />	<>	655	<xs:attribute name="cde" type="xs:string" default="3178387" />
530	<xs:attribute name="xsd_ver" type="xs:string" default="2.5" />		656	<xs:attribute name="xsd_ver" type="xs:string" default="2.4" />

   
File: TCGA_BCR.THCA_Clinical_FollowUp_v2.0.xsd  

1	<?xml version="1.0" encoding="utf-8" ?>	+-
3	<xs:schema elementFormDefault="qualified" version="2.5.0"	+-
4	xmlns:xs="http://www.w3.org/2001/XMLSchema"
5	xmlns:shared="http://tcga.nci/bcr/xml/clinical/shared/2.5"
6	xmlns:utility="http://tcga.nci/bcr/xml/utility/2.5"
7	xmlns:admin="http://tcga.nci/bcr/xml/administration/2.5"
8	xmlns:rad="http://tcga.nci/bcr/xml/clinical/radiation/2.5"
9	xmlns:thca_shared="http://tcga.nci/bcr/xml/clinical/thca/shared/2.5"
10	xmlns="http://tcga.nci/bcr/xml/clinical/thca/followup/2.5/2.0"
11	targetNamespace="http://tcga.nci/bcr/xml/clinical/thca/followup/2.5/2.0"
12	xmlns:jaxb="http://java.sun.com/xml/ns/jaxb" jaxb:version="1.0" >
14	<xs:import namespace="http://tcga.nci/bcr/xml/utility/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/utility/2.5/TCGA_BCR.Utility.xsd" />	+-
15	<xs:import namespace="http://tcga.nci/bcr/xml/administration/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/administration/2.5/TCGA_BCR.Administration.xsd" />
16	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/radiation/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/radiation/2.5/TCGA_BCR.Radiation.xsd" />
17	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/shared/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/shared/2.5/TCGA_BCR.Shared_Clinical_Elements.xsd" />
18	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/thca/shared/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/thca/shared/2.5/TCGA_BCR.THCA_Clinical_Shared_Datatypes.xsd" />
19	<xs:annotation>
20	<xs:appinfo>
21	<jaxb:globalBindings generateIsSetMethod="true" />
22	<jaxb:schemaBindings>
23	<jaxb:package name="nci.tcga.bcr.xml.jaxb.clinical.thca" />
24	</jaxb:schemaBindings>
25	</xs:appinfo>
26	</xs:annotation>
27	<xs:annotation>
28	<xs:documentation xml:lang="en">Schema to define the elements of the TCGA Clinical Data Follow-up Form within the THCA study.</xs:documentation>
29	</xs:annotation>
30	<xs:element name="follow_up_v2.0">
31	<xs:complexType>
32	<xs:sequence>
33	<xs:element ref="shared:bcr_patient_barcode" />
34	<xs:element ref="shared:bcr_patient_uuid" />
36	<xs:element ref="shared:followup_case_report_form_submission_reason" />	+-
37	<xs:element ref="shared:radiation_therapy" />
38	<xs:element ref="shared:targeted_molecular_therapy" />
39	<xs:element ref="thca_shared:i_131_total_administered_preparation_technique" />
40	<xs:element ref="thca_shared:i_131_first_administered_dose" />
41	<xs:element ref="thca_shared:i_131_subsequent_administered_dose" />
42	<xs:element ref="thca_shared:i_131_total_administered_dose" />
43	<xs:element ref="thca_shared:radiation_therapy_administered_preparation_technique_text" />
44	<xs:element ref="thca_shared:radiation_therapy_administered_dose_text" />
45	<xs:element ref="thca_shared:radiosensitizing_agent_administered_indicator" />
46	<xs:element ref="thca_shared:post_surgical_procedure_assessment_thyroid_gland_carcinoma_status" />
47	<xs:element ref="shared:vital_status" />
48	<xs:choice>
49	<xs:annotation><xs:documentation>
50	Data for the DATE_of_last_followup elements are also asked on the
51	TCGA Clinical Data Form during initial enrollment within the THCA study.
52	</xs:documentation></xs:annotation>
53	<xs:sequence>
54	<xs:element ref="shared:day_of_last_followup" />
55	<xs:element ref="shared:month_of_last_followup" />
56	<xs:element ref="shared:year_of_last_followup" />
57	</xs:sequence>
58	<xs:element ref="shared:days_to_last_followup" />
59	</xs:choice>
61	<xs:choice>	+-
62	<xs:annotation><xs:documentation>
63	Data for the DATE_of_death elements are also asked on the
64	TCGA Clinical Data Form during initial enrollment within the THCA study.
65	</xs:documentation></xs:annotation>
66	<xs:sequence>
67	<xs:element ref="shared:day_of_death" />
68	<xs:element ref="shared:month_of_death" />
69	<xs:element ref="shared:year_of_death" />
70	</xs:sequence>
71	<xs:element ref="shared:days_to_death" />
72	</xs:choice>
73	<xs:element ref="shared:person_neoplasm_cancer_status" />
74	<xs:element ref="new_tumor" />
75	<xs:choice>
76	<xs:annotation>
77	<xs:documentation>
78	Date the interviewer originally completed the corresponding TCGA Clinical Data Form.
79	If modifications are made after the form is marked complete, this date should not change.
80	</xs:documentation>
81	</xs:annotation>
82	<xs:sequence>
83	<xs:element ref="shared:day_of_form_completion" />
84	<xs:element ref="shared:month_of_form_completion" />
85	<xs:element ref="shared:year_of_form_completion" />
86	</xs:sequence>
87	<xs:element ref="shared:days_to_form_completion" />
88	</xs:choice>
89	</xs:sequence>
90	<xs:attribute name="version" type="xs:string" default="2.0" use="optional"/>
91	</xs:complexType>
92	</xs:element>
94	<xs:element name="new_tumor">	+-
95	<xs:complexType>
96	<xs:sequence>
97	<xs:element ref="shared:new_tumor_event_after_initial_treatment" />
98	<xs:choice>
99	<xs:sequence>
100	<xs:element ref="shared:day_of_new_tumor_event_after_initial_treatment" />
101	<xs:element ref="shared:month_of_new_tumor_event_after_initial_treatment" />
102	<xs:element ref="shared:year_of_new_tumor_event_after_initial_treatment" />
103	</xs:sequence>
105	<xs:element ref="shared:days_to_new_tumor_event_after_initial_treatment" />	+-
106	</xs:choice>
107	<xs:element ref="thca_shared:new_neoplasm_confirmed_diagnosis_method_name" />
108	<xs:element ref="thca_shared:histologic_disease_progression_present_indicator" />
109	<xs:element ref="thca_shared:histologic_disease_progression_present_type" />
110	<xs:element ref="thca_shared:histologic_disease_progression_present_text" />
111	<xs:element ref="shared:new_neoplasm_event_type" />
112	<xs:element ref="thca_shared:new_neoplasm_event_occurrence_anatomic_site" />
113	<xs:element ref="thca_shared:new_neoplasm_occurrence_anatomic_site_text" />
114	<xs:element ref="thca_shared:thyroid_gland_carcinoma_involvement_regional_lymph_node_type" />
115	<xs:element ref="thca_shared:thyroid_gland_carcinoma_regional_lymph_node_involvement_anatomic_sites_text" />
116	<xs:element ref="thca_shared:therapeutic_procedure_new_neoplasm_required_additional_therapy_type" />
117	<xs:element ref="shared:additional_surgery_locoregional_procedure" />
119	<xs:element ref="thca_shared:i_131_total_administered_preparation_technique" />	+-
120	<xs:element ref="thca_shared:i_131_first_administered_dose" />
121	<xs:element ref="thca_shared:i_131_subsequent_administered_dose" />
122	<xs:element ref="thca_shared:i_131_total_administered_dose" />
123	<xs:element ref="thca_shared:radiation_therapy_administered_preparation_technique_text" />
124	<xs:element ref="thca_shared:radiation_therapy_administered_dose_text" />
125	<xs:element ref="thca_shared:radiosensitizing_agent_administered_indicator" />
127	<xs:choice>	+-
128	<xs:sequence>
129	<xs:element ref="shared:day_of_additional_surgery_metastatic_procedure" />
130	<xs:element ref="shared:month_of_additional_surgery_metastatic_procedure" />
131	<xs:element ref="shared:year_of_additional_surgery_metastatic_procedure" />
132	</xs:sequence>
133	<xs:element ref="shared:days_to_additional_surgery_metastatic_procedure" />
134	</xs:choice>
136	<xs:element ref="shared:additional_radiation_therapy" />	+-
137	<xs:element ref="shared:additional_pharmaceutical_therapy" />
138	</xs:sequence>
139	</xs:complexType>
140	</xs:element>
143	</xs:schema>	+-

   
File: TCGA_BCR.THCA_Clinical_Shared_Datatypes.xsd  

1	<?xml version="1.0" encoding="utf-8" ?>	+-
4	<xs:schema elementFormDefault="qualified" version="2.5.0"	+-
5	xmlns:xs="http://www.w3.org/2001/XMLSchema"
6	xmlns:utility="http://tcga.nci/bcr/xml/utility/2.5"
7	xmlns="http://tcga.nci/bcr/xml/clinical/thca/shared/2.5"
8	targetNamespace="http://tcga.nci/bcr/xml/clinical/thca/shared/2.5">
10	<xs:import namespace="http://tcga.nci/bcr/xml/utility/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/utility/2.5/TCGA_BCR.Utility.xsd" />	+-
12	<xs:element name="i_131_total_administered_preparation_technique" nillable="true">	+-
13	<xs:complexType mixed="true">
14	<xs:simpleContent>
15	<xs:restriction base="utility:clinical_res_attributes">
16	<xs:enumeration value="" />
17	<xs:enumeration value="rhTSH" />
18	<xs:enumeration value="Thyroxine withdrawal" />
19	<xs:enumeration value="Patient did not receive I-131 treatment" />
20	<xs:attribute name="cde" type="xs:string" default="3232952" />
21	<xs:attribute name="xsd_ver" type="xs:string" default="2.5" />
22	<xs:attribute name="tier" type="xs:string" default="2" />
23	</xs:restriction>
24	</xs:simpleContent>
25	</xs:complexType>
26	</xs:element>
28	<xs:element name="i_131_first_administered_dose" nillable="true">	+-
29	<xs:complexType>
30	<xs:simpleContent>
31	<xs:extension base="xs:string">
32	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
33	<xs:attribute name="cde" type="xs:string" default="3232898" />
34	<xs:attribute name="xsd_ver" type="xs:string" default="2.4" />
35	<xs:attribute name="tier" type="xs:string" default="2" />
36	</xs:extension>
37	</xs:simpleContent>
38	</xs:complexType>
39	</xs:element>
41	<xs:element name="i_131_subsequent_administered_dose" nillable="true">	+-
42	<xs:complexType>
43	<xs:simpleContent>
44	<xs:extension base="xs:string">
45	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
46	<xs:attribute name="cde" type="xs:string" default="3232904" />
47	<xs:attribute name="xsd_ver" type="xs:string" default="2.4" />
48	<xs:attribute name="tier" type="xs:string" default="2" />
49	</xs:extension>
50	</xs:simpleContent>
51	</xs:complexType>
52	</xs:element>
54	<xs:element name="i_131_total_administered_dose" nillable="true">	+-
55	<xs:complexType>
56	<xs:simpleContent>
57	<xs:extension base="xs:string">
58	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
59	<xs:attribute name="cde" type="xs:string" default="3232906" />
60	<xs:attribute name="xsd_ver" type="xs:string" default="2.4" />
61	<xs:attribute name="tier" type="xs:string" default="2" />
62	</xs:extension>
63	</xs:simpleContent>
64	</xs:complexType>
65	</xs:element>
67	<xs:element name="radiation_therapy_administered_preparation_technique_text" nillable="true">	+-
68	<xs:complexType>
69	<xs:simpleContent>
70	<xs:extension base="xs:string">
71	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
72	<xs:attribute name="cde" type="xs:string" default="3232960" />
73	<xs:attribute name="xsd_ver" type="xs:string" default="2.4" />
74	<xs:attribute name="tier" type="xs:string" default="2" />
75	</xs:extension>
76	</xs:simpleContent>
77	</xs:complexType>
78	</xs:element>
80	<xs:element name="radiation_therapy_administered_dose_text" nillable="true">	+-
81	<xs:complexType>
82	<xs:simpleContent>
83	<xs:extension base="xs:string">
84	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
85	<xs:attribute name="cde" type="xs:string" default="3232933" />
86	<xs:attribute name="xsd_ver" type="xs:string" default="2.4" />
87	<xs:attribute name="tier" type="xs:string" default="2" />
88	</xs:extension>
89	</xs:simpleContent>
90	</xs:complexType>
91	</xs:element>
93	<xs:element name="radiosensitizing_agent_administered_indicator" nillable="true">	+-
94	<xs:complexType>
95	<xs:simpleContent>
96	<xs:extension base="utility:yes_or_no">
97	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
98	<xs:attribute name="cde" type="xs:string" default="3232932" />
99	<xs:attribute name="xsd_ver" type="xs:string" default="2.4" />
100	<xs:attribute name="tier" type="xs:string" default="1" />
101	</xs:extension>
102	</xs:simpleContent>
103	</xs:complexType>
104	</xs:element>
106	<xs:element name="post_surgical_procedure_assessment_thyroid_gland_carcinoma_status" nillable="true">	+-
107	<xs:complexType mixed="true">
108	<xs:simpleContent>
109	<xs:restriction base="utility:clinical_res_attributes">
110	<xs:enumeration value="" />
111	<xs:enumeration value="No imaging evidence of disease" />
112	<xs:enumeration value="Persistent locoregional disease" />
113	<xs:enumeration value="Persistent distant metastases" />
114	<xs:attribute name="cde" type="xs:string" default="3186684" />
115	<xs:attribute name="xsd_ver" type="xs:string" default="2.4" />
116	<xs:attribute name="tier" type="xs:string" default="2" />
117	</xs:restriction>
118	</xs:simpleContent>
119	</xs:complexType>
120	</xs:element>
122	<xs:element name="new_neoplasm_confirmed_diagnosis_method_name" nillable="true">	+-
123	<xs:complexType mixed="true">
124	<xs:simpleContent>
125	<xs:restriction base="utility:clinical_res_attributes">
126	<xs:enumeration value="" />
127	<xs:enumeration value="Imaging" />
128	<xs:enumeration value="Pathology" />
129	<xs:attribute name="cde" type="xs:string" default="3186701" />
130	<xs:attribute name="xsd_ver" type="xs:string" default="2.4" />
131	<xs:attribute name="tier" type="xs:string" default="2" />
132	</xs:restriction>
133	</xs:simpleContent>
134	</xs:complexType>
135	</xs:element>
137	<xs:element name="histologic_disease_progression_present_indicator" nillable="true">	+-
138	<xs:complexType>
139	<xs:simpleContent>
140	<xs:extension base="utility:yes_or_no">
141	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
142	<xs:attribute name="cde" type="xs:string" default="3181376" />
143	<xs:attribute name="xsd_ver" type="xs:string" default="2.4" />
144	<xs:attribute name="tier" type="xs:string" default="1" />
145	</xs:extension>
146	</xs:simpleContent>
147	</xs:complexType>
148	</xs:element>
150	<xs:element name="histologic_disease_progression_present_type" nillable="true">	+-
151	<xs:complexType mixed="true">
152	<xs:simpleContent>
153	<xs:restriction base="utility:clinical_res_attributes">
154	<xs:enumeration value="" />
155	<xs:enumeration value="Poorly differentiated" />
156	<xs:enumeration value="Anaplastic" />
157	<xs:enumeration value="Other, specify" />
158	<xs:attribute name="cde" type="xs:string" default="3181384" />
159	<xs:attribute name="xsd_ver" type="xs:string" default="2.4" />
160	<xs:attribute name="tier" type="xs:string" default="2" />
161	</xs:restriction>
162	</xs:simpleContent>
163	</xs:complexType>
164	</xs:element>
166	<xs:element name="histologic_disease_progression_present_text" nillable="true">	+-
167	<xs:complexType>
168	<xs:simpleContent>
169	<xs:extension base="xs:string">
170	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
171	<xs:attribute name="cde" type="xs:string" default="3181387" />
172	<xs:attribute name="xsd_ver" type="xs:string" default="2.4" />
173	<xs:attribute name="tier" type="xs:string" default="2" />
174	</xs:extension>
175	</xs:simpleContent>
176	</xs:complexType>
177	</xs:element>
179	<xs:element name="new_neoplasm_event_occurrence_anatomic_site" nillable="true">	+-
180	<xs:complexType mixed="true">
181	<xs:simpleContent>
182	<xs:restriction base="utility:clinical_res_attributes">
183	<xs:enumeration value="" />
184	<xs:enumeration value="Renal Pelvis" />
185	<xs:enumeration value="Soft Tissue" />
186	<xs:enumeration value="Ureter" />
187	<xs:enumeration value="Lung" />
188	<xs:enumeration value="Urethra" />
189	<xs:enumeration value="Lymph Node Only" />
190	<xs:enumeration value="Other, specify" />
191	<xs:enumeration value="Liver" />
192	<xs:enumeration value="Bone" />
193	<xs:enumeration value="Bladder" />
194	<xs:attribute name="cde" type="xs:string" default="3108271" />
195	<xs:attribute name="xsd_ver" type="xs:string" default="2.4" />
196	<xs:attribute name="tier" type="xs:string" default="2" />
197	</xs:restriction>
198	</xs:simpleContent>
199	</xs:complexType>
200	</xs:element>
202	<xs:element name="new_neoplasm_occurrence_anatomic_site_text" nillable="true">	+-
203	<xs:complexType>
204	<xs:simpleContent>
205	<xs:extension base="xs:string">
206	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
207	<xs:attribute name="cde" type="xs:string" default="3128033" />
208	<xs:attribute name="xsd_ver" type="xs:string" default="2.4" />
209	<xs:attribute name="tier" type="xs:string" default="2" />
210	</xs:extension>
211	</xs:simpleContent>
212	</xs:complexType>
213	</xs:element>
215	<xs:element name="thyroid_gland_carcinoma_involvement_regional_lymph_node_type" nillable="true">	+-
216	<xs:complexType mixed="true">
217	<xs:simpleContent>
218	<xs:restriction base="utility:clinical_res_attributes">
219	<xs:enumeration value="" />
220	<xs:enumeration value="Central (levels 6-7)" />
221	<xs:enumeration value="Lateral (levels 2-5)" />
222	<xs:enumeration value="Other" />
223	<xs:attribute name="cde" type="xs:string" default="3186207" />
224	<xs:attribute name="xsd_ver" type="xs:string" default="2.4" />
225	<xs:attribute name="tier" type="xs:string" default="2" />
226	</xs:restriction>
227	</xs:simpleContent>
228	</xs:complexType>
229	</xs:element>
231	<xs:element name="thyroid_gland_carcinoma_regional_lymph_node_involvement_anatomic_sites_text" nillable="true">	+-
232	<xs:complexType>
233	<xs:simpleContent>
234	<xs:extension base="xs:string">
235	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
236	<xs:attribute name="cde" type="xs:string" default="3185693" />
237	<xs:attribute name="xsd_ver" type="xs:string" default="2.4" />
238	<xs:attribute name="tier" type="xs:string" default="2" />
239	</xs:extension>
240	</xs:simpleContent>
241	</xs:complexType>
242	</xs:element>
244	<xs:element name="therapeutic_procedure_new_neoplasm_required_additional_therapy_type" nillable="true">	+-
245	<xs:complexType mixed="true">
246	<xs:simpleContent>
247	<xs:restriction base="utility:clinical_res_attributes">
248	<xs:enumeration value="" />
249	<xs:enumeration value="Surgery (distant metastasis) or Surgery (loco-regional)" />
250	<xs:enumeration value="RAI therapy" />
251	<xs:enumeration value="EBRT" />
252	<xs:enumeration value="Pharmaceutical therapy" />
253	<xs:attribute name="cde" type="xs:string" default="3185186" />
254	<xs:attribute name="xsd_ver" type="xs:string" default="2.4" />
255	<xs:attribute name="tier" type="xs:string" default="2" />
256	</xs:restriction>
257	</xs:simpleContent>
258	</xs:complexType>
259	</xs:element>
261	</xs:schema>	+-

   
File: TCGA_BCR.UCEC_Clinical.xsd  

4	<xs:schema elementFormDefault="qualified" version="2.5.0"	<>	4	<xs:schema elementFormDefault="qualified" version="2.4.4"
6	xmlns:utility="http://tcga.nci/bcr/xml/utility/2.5"	<>	6	xmlns:utility="http://tcga.nci/bcr/xml/utility/2.4"
7	xmlns:admin="http://tcga.nci/bcr/xml/administration/2.5"		7	xmlns:admin="http://tcga.nci/bcr/xml/administration/2.4"
8	xmlns:shared="http://tcga.nci/bcr/xml/clinical/shared/2.5"		8	xmlns:shared="http://tcga.nci/bcr/xml/clinical/shared/2.4"
9	xmlns:ucec_shared="http://tcga.nci/bcr/xml/clinical/ucec/shared/2.5"
10	xmlns:rad="http://tcga.nci/bcr/xml/clinical/radiation/2.5"		9	xmlns:rad="http://tcga.nci/bcr/xml/clinical/radiation/2.4"
11	xmlns:rx="http://tcga.nci/bcr/xml/clinical/pharmaceutical/2.5"		10	xmlns:rx="http://tcga.nci/bcr/xml/clinical/pharmaceutical/2.4"
12	xmlns:cqcf="http://tcga.nci/bcr/xml/clinical/cqcf/2.5"
13	xmlns:follow_up_v1.7="http://tcga.nci/bcr/xml/clinical/ucec/followup/2.5/1.7"
14	xmlns:follow_up_v2.0="http://tcga.nci/bcr/xml/clinical/ucec/followup/2.5/2.0"
15	xmlns="http://tcga.nci/bcr/xml/clinical/ucec/2.5"		11	xmlns="http://tcga.nci/bcr/xml/clinical/ucec/2.4"
16	targetNamespace="http://tcga.nci/bcr/xml/clinical/ucec/2.5"		12	targetNamespace="http://tcga.nci/bcr/xml/clinical/ucec/2.4"
32	<xs:import namespace="http://tcga.nci/bcr/xml/utility/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/utility/2.5/TCGA_BCR.Utility.xsd" />	<>	28	<xs:import namespace="http://tcga.nci/bcr/xml/utility/2.4" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/utility/2.4/TCGA_BCR.Utility.xsd" />
33	<xs:import namespace="http://tcga.nci/bcr/xml/administration/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/administration/2.5/TCGA_BCR.Administration.xsd" />		29	<xs:import namespace="http://tcga.nci/bcr/xml/administration/2.4" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/administration/2.4/TCGA_BCR.Administration.xsd" />
34	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/shared/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/shared/2.5/TCGA_BCR.Shared_Clinical_Elements.xsd" />		30	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/shared/2.4" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/shared/2.4/TCGA_BCR.Shared_Clinical_Elements.xsd" />
35	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/radiation/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/radiation/2.5/TCGA_BCR.Radiation.xsd" />		31	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/radiation/2.4" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/radiation/2.4/TCGA_BCR.Radiation.xsd" />
36	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/pharmaceutical/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/pharmaceutical/2.5/TCGA_BCR.Pharmaceutical.xsd" />		32	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/pharmaceutical/2.4" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/pharmaceutical/2.4/TCGA_BCR.Pharmaceutical.xsd" />
37	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/cqcf/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/cqcf/2.5/TCGA_BCR.CQCF.xsd" />
38	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/ucec/shared/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/ucec/shared/2.5/TCGA_BCR.UCEC_Clinical_Shared_Datatypes.xsd" />
39	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/ucec/followup/2.5/1.7" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/ucec/followup/2.5/TCGA_BCR.UCEC_Clinical_FollowUp_v1.7.xsd" />
40	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/ucec/followup/2.5/2.0" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/ucec/followup/2.5/TCGA_BCR.UCEC_Clinical_FollowUp_v2.0.xsd" />
49	<xs:attribute name="schemaVersion" type="xs:decimal" use="required" fixed="2.5"/>	<>	41	<xs:attribute name="schemaVersion" type="xs:decimal" use="required" fixed="2.4"/>
56	<xs:element ref="shared:tissue_source_site" />	<>	48	<xs:element ref="shared:tumor_tissue_site" />
57	<xs:element ref="shared:patient_id" />
58	<xs:element ref="shared:bcr_patient_barcode" />		49	<xs:element ref="primary_other_site_of_disease_name" />
59	<xs:element ref="shared:bcr_patient_uuid" />		50	<xs:element ref="histological_type" />
60	<xs:element ref="shared:informed_consent_verified" />		51	<xs:element ref="shared:prior_diagnosis" />
61	<xs:element ref="shared:icd_o_3_site" />		52	<xs:element ref="shared:gender" />
62	<xs:element ref="shared:icd_o_3_histology" />
63	<xs:element ref="shared:icd_10" />		53	<xs:element ref="shared:vital_status" />
65	<xs:element ref="tissue_prospective_collection_indicator" />	+-
66	<xs:element ref="tissue_retrospective_collection_indicator" />
75	<xs:element ref="shared:gender" />	<>	64
76	<xs:element ref="menopause_status" />
77	<xs:element ref="shared:height" />
78	<xs:element ref="shared:weight" />
79	<xs:element ref="shared:race" />
80	<xs:element ref="shared:ethnicity" />
81	<xs:element ref="shared:prior_diagnosis" />
82	<xs:element ref="shared:pretreatment_history" />
83	<xs:element ref="shared:vital_status">
84	<xs:annotation>
85	<xs:documentation xml:lang="en">The vital_status question is asked in both the initial enrollment form and the follow-up form(s).</xs:documentation>
86	</xs:annotation>
87	</xs:element>
89	<xs:annotation>	+-
90	<xs:documentation xml:lang="en">The date_of_last_followup question is asked in both the initial enrollment form and the follow-up form(s).</xs:documentation>
91	</xs:annotation>
92	<xs:sequence>
93	<xs:element ref="shared:day_of_last_followup" />
94	<xs:element ref="shared:month_of_last_followup" />
95	<xs:element ref="shared:year_of_last_followup" />
96	</xs:sequence>
97	<xs:element ref="shared:days_to_last_followup" />
98	</xs:choice>
99	<xs:choice>
100	<xs:annotation>
101	<xs:documentation xml:lang="en">
102	The date_of_last_known_alive question is asked in both the initial enrollment form and the follow-up form(s).
104	DEPRECATED:	+-
105	This question is no longer asked on the TCGA Clinical Data initial enrollment form or follow-up Forms (starting with v2.0)
106	within the UCEC study.
107	</xs:documentation>
108	</xs:annotation>
118	<xs:annotation>	+-
119	<xs:documentation xml:lang="en">The date_of_death question is asked in both the initial enrollment form and the follow-up form(s).</xs:documentation>
120	</xs:annotation>
		<>	85	<xs:choice>
			86	<xs:sequence>
			87	<xs:element ref="shared:day_of_last_followup" />
			88	<xs:element ref="shared:month_of_last_followup" />
128	<xs:element ref="shared:person_neoplasm_cancer_status">		89	<xs:element ref="shared:year_of_last_followup" />
129	<xs:annotation>		90	</xs:sequence>
130	<xs:documentation xml:lang="en">The person_neoplasm_cancer_status question is asked in both the initial enrollment form and the follow-up form(s).</xs:documentation>		91
			92	<xs:element ref="shared:days_to_last_followup" />
131	</xs:annotation>		93	</xs:choice>
132	</xs:element>	<>	95	<xs:element ref="shared:race" />
133			96	<xs:element ref="shared:bcr_patient_barcode" />
134	<xs:element ref="shared:tumor_tissue_site" />		97	<xs:element ref="shared:tissue_source_site" />
135	<xs:element ref="primary_other_site_of_disease_name">		98	<xs:element ref="shared:patient_id" />
136	<xs:annotation><xs:documentation>		99	<xs:element ref="shared:bcr_patient_uuid" />
137	Data for the primary_other_site_of_disease_name element is *only* asked on the		100	<xs:element ref="shared:pretreatment_history" />
138	TCGA Clinical Data Form during initial enrollment within the UCEC study, *and only* when		101	<xs:element ref="shared:radiation_therapy" />
139	an answer of 'Other (please specify)' is provided for tumor_tissue_site.		102	<xs:element ref="shared:informed_consent_verified" />
140	</xs:documentation></xs:annotation>		103	<xs:element ref="shared:icd_o_3_site" />
141	</xs:element>
142	<xs:element ref="histological_type" />		104	<xs:element ref="shared:icd_o_3_histology" />
			105	<xs:element ref="shared:icd_10" />
		<>	121	<xs:choice>
			122	<xs:sequence>
154	<xs:element ref="shared:initial_pathologic_diagnosis_method" />		123	<xs:element ref="shared:day_of_new_tumor_event_after_initial_treatment" />
			124	<xs:element ref="shared:month_of_new_tumor_event_after_initial_treatment" />
			125	<xs:element ref="shared:year_of_new_tumor_event_after_initial_treatment" />
			126	</xs:sequence>
155	<xs:element ref="first_pathologic_diagnosis_biospecimen_acquisition_other_method_text">	<>	128	<xs:element ref="shared:days_to_new_tumor_event_after_initial_treatment" />
			129	</xs:choice>
		<>	131	<xs:element ref="gynecologic_figo_staging_system" />
156	<xs:annotation><xs:documentation xml:lang="en">		132	<xs:element ref="endometrial_carcinoma_figo_stage" />
			133	<xs:element ref="tumor_grade" />
			134	<xs:element ref="primary_therapy_outcome_success" />
			135	<xs:element ref="shared:ethnicity" />
			136	<xs:element ref="shared:additional_radiation_therapy" />
			137	<xs:element ref="shared:additional_pharmaceutical_therapy" />
			138	<xs:element ref="shared:additional_surgery_locoregional_procedure" />
		<>	140	<xs:choice>
			141	<xs:sequence>
			142	<xs:element ref="shared:day_of_additional_surgery_metastatic_procedure" />
157	Data for the first_pathologic_diagnosis_biospecimen_acquisition_other_method_text element is *only* asked on the		143	<xs:element ref="shared:month_of_additional_surgery_metastatic_procedure" />
158	TCGA Clinical Data Form during initial enrollment within the UCEC study, *and only* when
159	an answer of 'Other method (please specify)' is provided for first_pathologic_diagnosis_biospecimen_acquisition_method_type.		144	<xs:element ref="shared:year_of_additional_surgery_metastatic_procedure" />
160	</xs:documentation></xs:annotation>
161	</xs:element>		145	</xs:sequence>
		-+	147	<xs:element ref="shared:days_to_additional_surgery_metastatic_procedure" />
			148	</xs:choice>
162	<xs:element ref="surgical_approach" />	<>	150	<xs:element ref="shared:person_neoplasm_cancer_status" />
			151	<xs:element ref="shared:height" />
163	<xs:element ref="peritoneal_wash" />		152	<xs:element ref="shared:weight" />
			153	<xs:element ref="first_pathologic_diagnosis_biospecimen_acquisition_method_type" />
			154	<xs:element ref="first_pathologic_diagnosis_biospecimen_acquisition_other_method_text" />
		<>	156	<xs:element ref="peritoneal_wash" />
165	<xs:element ref="gynecologic_figo_staging_system">		157	<xs:element ref="prosp_tissue_coll" />
166	<xs:annotation><xs:documentation xml:lang="en">
167	Data for the gynecologic_figo_staging_system element is only asked on the
168	*version 2.08* and later of the TCGA Clinical Data Form during initial enrollment
169	within the UCEC study.
170	</xs:documentation></xs:annotation>
171	</xs:element>
172	<xs:element ref="gynecologic_tumor_grouping_figo_stage" />		158	<xs:element ref="retro_tissue_coll" />
173	<xs:element ref="tumor_grade" />		159	<xs:element ref="surgical_approach" />
174	<xs:element ref="shared:residual_tumor" />		160	<xs:element ref="menopause_status" />
175	<xs:element ref="total_pelv_lnr" />		161	<xs:element ref="aln_pos_ihc" />
176	<xs:element ref="pln_pos_light_micro" />		162	<xs:element ref="aln_pos_light_micro" />
		<>	164	<xs:element ref="pln_pos_light_micro" />
178	<xs:element ref="total_pelv_lnp" />		165	<xs:element ref="total_aor-lnp" />
		<>	167	<xs:element ref="total_pelv_lnp" />
180	<xs:element ref="aln_pos_light_micro" />		168	<xs:element ref="total_pelv_lnr" />
			169	<xs:element ref="diabetes" />
			170	<xs:element ref="horm_ther" />
			171	<xs:element ref="hypertension" />
181	<xs:element ref="aln_pos_ihc" />		172	<xs:element ref="pregnancies" />
182	<xs:element ref="total_aor-lnp" />		173	<xs:element ref="colorectal_cancer" />
			174	<xs:element ref="addl_trtmt_success" />
			175	<xs:element ref="adjuvant_postoperative_targeted_therapy_administered_indicator" />
			176	<xs:element ref="birth_control_pill_history_usage_category" />
			177	<xs:element ref="prior_tamoxifen_administered_usage_category" />
			178	<xs:element ref="followup_met_assessment_outcome_success_margin_status" />
			179	<xs:element ref="recurrence_second_surgery_neoplasm_surgical_procedure_name" />
			180	<xs:element ref="recurrence_second_surgery_neoplasm_surgical_procedure_name_other" />
184	<xs:annotation>	+-
185	<xs:documentation xml:lang="en">
186	Date the interviewer originally completed the corresponding TCGA Clinical Data Form.
187	If modifications are made after the form is marked complete, this date should not change.
188	</xs:documentation>
189	</xs:annotation>
198	<xs:element ref="follow_ups" />	+-
201	<xs:element ref="clinical_cqcf" />	+-
206	<xs:element name="follow_ups">	+-
207	<xs:annotation>
208	<xs:documentation xml:lang="en">We are using namespaces and version numbers to distinguish one version of followup from another.</xs:documentation>
209	</xs:annotation>
210	<xs:complexType>
211	<xs:sequence>
212	<xs:element ref="follow_up_v1.7:follow_up_v1.7" minOccurs="0" maxOccurs="unbounded" />
213	<xs:element ref="follow_up_v2.0:follow_up_v2.0" minOccurs="0" maxOccurs="unbounded" />
214	</xs:sequence>
215	</xs:complexType>
216	</xs:element>
218	<xs:element name="clinical_cqcf">	+-
219	<xs:complexType>
220	<xs:sequence>
221	<xs:element ref="shared:anatomic_organ_subdivision"/>
222	<xs:element ref="cqcf:consent_or_death_status"/>
224	<xs:choice>	+-
225	<xs:choice>
226	<xs:sequence>
227	<xs:element ref="cqcf:day_of_consent"/>
228	<xs:element ref="cqcf:month_of_consent"/>
229	<xs:element ref="cqcf:year_of_consent"/>
230	</xs:sequence>
232	<xs:element ref="cqcf:days_to_consent"/>	+-
233	</xs:choice>
235	<xs:choice>	+-
236	<xs:sequence>
237	<xs:element ref="shared:day_of_death"/>
238	<xs:element ref="shared:month_of_death"/>
239	<xs:element ref="shared:year_of_death"/>
240	</xs:sequence>
242	<xs:element ref="shared:days_to_death"/>	+-
243	</xs:choice>
244	</xs:choice>
246	<xs:element ref="cqcf:diagnosis_subtype"/>	+-
247	<xs:element ref="shared:prior_diagnosis"/>
248	<xs:element ref="cqcf:history_of_neoadjuvant_treatment"/>
249	<xs:element ref="cqcf:normal_tissue_anatomic_site"/>
250	<xs:element ref="cqcf:normal_tissue_proximity"/>
251	<xs:element ref="cqcf:tumor_focality"/>
252	<xs:element ref="cqcf:tumor_type"/>
253	<xs:element ref="cqcf:other_diagnosis"/>
254	<xs:element ref="cqcf:histological_subtype" minOccurs="0"/>
255	<xs:element ref="cqcf:other_anatomic_site" minOccurs="0"/>
256	<xs:element ref="cqcf:country"/>
257	</xs:sequence>
258	</xs:complexType>
259	</xs:element>
315	<xs:element name="gynecologic_tumor_grouping_figo_stage" nillable="true">	<>	252	<xs:element name="endometrial_carcinoma_figo_stage" nillable="true">
		-+	304	<xs:element name="primary_therapy_outcome_success" nillable="true">
			305	<xs:complexType>
			306	<xs:simpleContent>
			307	<xs:restriction base="utility:clinical_res_attributes">
			308	<xs:enumeration value="" />
			309	<xs:enumeration value="Unknown" />
			310	<xs:enumeration value="Not Applicable" />
			311	<xs:enumeration value="Persistent Disease" />
			312	<xs:enumeration value="Progressive Disease" />
			313	<xs:enumeration value="Stable Disease" />
			314	<xs:enumeration value="Partial Response" />
			315	<xs:enumeration value="Complete Response" />
			316	<xs:attribute name="cde" type="xs:string" default="2786727" />
			317	<xs:attribute name="xsd_ver" type="xs:string" default="2.4" />
			318	<xs:attribute name="tier" type="xs:string" default="2" />
			319	</xs:restriction>
			320	</xs:simpleContent>
			321	</xs:complexType>
			322	</xs:element>
		-+	324	<xs:element name="first_pathologic_diagnosis_biospecimen_acquisition_method_type" nillable="true">
			325	<xs:complexType mixed="true">
			326	<xs:simpleContent>
			327	<xs:restriction base="utility:clinical_res_attributes">
			328	<xs:enumeration value="" />
			329	<xs:enumeration value="Other method specify:" />
			330	<xs:enumeration value="Aspirate" />
			331	<xs:enumeration value="Core needle biopsy" />
			332	<xs:enumeration value="Cytology (e.g. Peritoneal or pleural fluid)" />
			333	<xs:enumeration value="Dilation and curettage procedure" />
			334	<xs:enumeration value="Endoscopic Biopsy" />
			335	<xs:enumeration value="Excisional Biopsy" />
			336	<xs:enumeration value="Fine needle aspiration biopsy" />
			337	<xs:enumeration value="Incisional Biopsy" />
			338	<xs:enumeration value="Office Endometrial Biopsy" />
			339	<xs:enumeration value="Tumor resection" />
			340	<xs:attribute name="cde" type="xs:string" default="2757941" />
			341	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			342	<xs:attribute name="tier" type="xs:string" default="2" />
			343	</xs:restriction>
			344	</xs:simpleContent>
			345	</xs:complexType>
			346	</xs:element>
370	<xs:extension base="utility:number_or_null">	<>	351	<xs:extension base="xs:decimal">
398	<xs:element name="tissue_prospective_collection_indicator" nillable="true">	<>	379	<xs:element name="prosp_tissue_coll" nillable="true">
411	<xs:element name="tissue_retrospective_collection_indicator" nillable="true">	<>	392	<xs:element name="retro_tissue_coll" nillable="true">
459	<xs:extension base="utility:integer_or_null">	<>	440	<xs:extension base="xs:integer">
472	<xs:extension base="utility:integer_or_null">	<>	453	<xs:extension base="xs:integer">
485	<xs:extension base="utility:integer_or_null">	<>	466	<xs:extension base="xs:integer">
498	<xs:extension base="utility:integer_or_null">	<>	479	<xs:extension base="xs:integer">
511	<xs:extension base="utility:integer_or_null">	<>	492	<xs:extension base="xs:integer">
524	<xs:extension base="utility:integer_or_null">	<>	505	<xs:extension base="xs:integer">
537	<xs:extension base="utility:integer_or_null">	<>	518	<xs:extension base="xs:integer">
550	<xs:extension base="utility:integer_or_null">	<>	531	<xs:extension base="xs:integer">
		-+	554	<xs:simpleType name="number_or_not_available">
			555	<xs:union memberTypes="xs:decimal">
			556	<xs:simpleType>
			557	<xs:restriction base="xs:decimal" />
			558	</xs:simpleType>
		-+	560	<xs:simpleType>
			561	<xs:restriction base="xs:string">
			562	<xs:enumeration value="Not available"/>
			563	</xs:restriction>
			564	</xs:simpleType>
			565	</xs:union>
			566	</xs:simpleType>
		-+	568	<xs:element name="diabetes" nillable="true">
			569	<xs:complexType>
			570	<xs:simpleContent>
			571	<xs:extension base="utility:yes_or_no">
			572	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			573	<xs:attribute name="cde" type="xs:string" default="2716085" />
			574	<xs:attribute name="xsd_ver" type="xs:string" default="2.4" />
			575	<xs:attribute name="tier" type="xs:string" default="2" />
			576	</xs:extension>
			577	</xs:simpleContent>
			578	</xs:complexType>
			579	</xs:element>
		-+	581	<xs:element name="horm_ther" nillable="true">
			582	<xs:complexType mixed="true">
			583	<xs:simpleContent>
			584	<xs:restriction base="utility:clinical_res_attributes">
			585	<xs:enumeration value="" />
			586	<xs:enumeration value="Yes, I am currently taking menopausal hormone therapy." />
			587	<xs:enumeration value="Yes, I have taken menopausal hormone therapy in the past, but no longer do." />
			588	<xs:enumeration value="No, I have never taken menopausal hormone therapy." />
			589	<xs:enumeration value="48 months" />
			590	<xs:enumeration value="60 months" />
			591	<xs:attribute name="cde" type="xs:string" default="3012813" />
			592	<xs:attribute name="xsd_ver" type="xs:string" default="2.4" />
			593	<xs:attribute name="tier" type="xs:string" default="2" />
			594	</xs:restriction>
			595	</xs:simpleContent>
			596	</xs:complexType>
			597	</xs:element>
		-+	599	<xs:element name="hypertension" nillable="true">
			600	<xs:complexType>
			601	<xs:simpleContent>
			602	<xs:extension base="utility:yes_or_no">
			603	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			604	<xs:attribute name="cde" type="xs:string" default="2183378" />
			605	<xs:attribute name="xsd_ver" type="xs:string" default="2.4" />
			606	<xs:attribute name="tier" type="xs:string" default="2" />
			607	</xs:extension>
			608	</xs:simpleContent>
			609	</xs:complexType>
			610	</xs:element>
		-+	612	<xs:element name="pregnancies" nillable="true">
			613	<xs:complexType mixed="true">
			614	<xs:simpleContent>
			615	<xs:restriction base="utility:clinical_res_attributes">
			616	<xs:enumeration value="" />
			617	<xs:enumeration value="1" />
			618	<xs:enumeration value="2" />
			619	<xs:enumeration value="3" />
			620	<xs:enumeration value="4+" />
			621	<xs:attribute name="cde" type="xs:string" default="3012512" />
			622	<xs:attribute name="xsd_ver" type="xs:string" default="2.4" />
			623	<xs:attribute name="tier" type="xs:string" default="2" />
			624	</xs:restriction>
			625	</xs:simpleContent>
			626	</xs:complexType>
			627	</xs:element>
		-+	629	<xs:element name="colorectal_cancer" nillable="true">
			630	<xs:complexType>
			631	<xs:simpleContent>
			632	<xs:extension base="utility:yes_or_no">
			633	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			634	<xs:attribute name="cde" type="xs:string" default="2684753" />
			635	<xs:attribute name="xsd_ver" type="xs:string" default="2.4" />
			636	<xs:attribute name="tier" type="xs:string" default="2" />
			637	</xs:extension>
			638	</xs:simpleContent>
			639	</xs:complexType>
			640	</xs:element>
		-+	642	<xs:element name="addl_trtmt_success" nillable="true">
			643	<xs:complexType mixed="true">
			644	<xs:simpleContent>
			645	<xs:restriction base="utility:clinical_res_attributes">
			646	<xs:enumeration value="" />
			647	<xs:enumeration value="Progressive Disease" />
			648	<xs:enumeration value="Stable Disease" />
			649	<xs:enumeration value="Partial Response" />
			650	<xs:enumeration value="Complete Response" />
			651	<xs:attribute name="cde" type="xs:string" default="3033278" />
			652	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			653	<xs:attribute name="tier" type="xs:string" default="1" />
			654	</xs:restriction>
			655	</xs:simpleContent>
			656	</xs:complexType>
			657	</xs:element>
		-+	659	<xs:element name="adjuvant_postoperative_targeted_therapy_administered_indicator" nillable="true">
			660	<xs:complexType>
			661	<xs:simpleContent>
			662	<xs:extension base="utility:yes_or_no">
			663	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			664	<xs:attribute name="cde" type="xs:string" default="2785850" />
			665	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			666	<xs:attribute name="tier" type="xs:string" default="1" />
			667	</xs:extension>
			668	</xs:simpleContent>
			669	</xs:complexType>
			670	</xs:element>
		-+	672	<xs:element name="birth_control_pill_history_usage_category" nillable="true">
			673	<xs:complexType mixed="true">
			674	<xs:simpleContent>
			675	<xs:restriction base="utility:clinical_res_attributes">
			676	<xs:enumeration value="" />
			677	<xs:enumeration value="Current User" />
			678	<xs:enumeration value="Former User" />
			679	<xs:enumeration value="Never Used" />
			680	<xs:enumeration value="Unknown" />
			681	<xs:attribute name="cde" type="xs:string" default="3104217" />
			682	<xs:attribute name="xsd_ver" type="xs:string" default="2.4" />
			683	<xs:attribute name="tier" type="xs:string" default="2" />
			684	</xs:restriction>
			685	</xs:simpleContent>
			686	</xs:complexType>
			687	</xs:element>
		-+	689	<xs:element name="prior_tamoxifen_administered_usage_category" nillable="true">
			690	<xs:complexType mixed="true">
			691	<xs:simpleContent>
			692	<xs:restriction base="utility:clinical_res_attributes">
			693	<xs:enumeration value="" />
			694	<xs:enumeration value="Current User (This is an exclusion criterion)" />
			695	<xs:enumeration value="Former User (This is an exclusion criterion)" />
			696	<xs:enumeration value="Never Used" />
			697	<xs:attribute name="cde" type="xs:string" default="3104234" />
			698	<xs:attribute name="xsd_ver" type="xs:string" default="2.4" />
			699	<xs:attribute name="tier" type="xs:string" default="2" />
			700	</xs:restriction>
			701	</xs:simpleContent>
			702	</xs:complexType>
			703	</xs:element>
		-+	705	<xs:element name="followup_met_assessment_outcome_success_margin_status" nillable="true">
			706	<xs:complexType mixed="true">
			707	<xs:simpleContent>
			708	<xs:restriction base="utility:clinical_res_attributes">
			709	<xs:enumeration value="" />
			710	<xs:enumeration value="R0" />
			711	<xs:enumeration value="R1" />
			712	<xs:enumeration value="R2" />
			713	<xs:enumeration value="RX" />
			714	<xs:attribute name="cde" type="xs:string" default="2608702" />
			715	<xs:attribute name="xsd_ver" type="xs:string" default="2.4" />
			716	<xs:attribute name="tier" type="xs:string" default="2" />
			717	</xs:restriction>
			718	</xs:simpleContent>
			719	</xs:complexType>
			720	</xs:element>
		-+	722	<xs:element name="recurrence_second_surgery_neoplasm_surgical_procedure_name" nillable="true">
			723	<xs:complexType mixed="true">
			724	<xs:simpleContent>
			725	<xs:restriction base="utility:clinical_res_attributes">
			726	<xs:enumeration value="" />
			727	<xs:enumeration value="Excisional Biopsy" />
			728	<xs:enumeration value="Incisional Biopsy" />
			729	<xs:enumeration value="Surgical Resection" />
			730	<xs:enumeration value="Other Method, Specify Below" />
			731	<xs:attribute name="cde" type="xs:string" default="3125097" />
			732	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			733	<xs:attribute name="tier" type="xs:string" default="2" />
			734	</xs:restriction>
			735	</xs:simpleContent>
			736	</xs:complexType>
			737	</xs:element>
		-+	739	<xs:element name="recurrence_second_surgery_neoplasm_surgical_procedure_name_other" nillable="true">
			740	<xs:complexType>
			741	<xs:simpleContent>
			742	<xs:extension base="xs:string">
			743	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
			744	<xs:attribute name="cde" type="xs:string" default="3125102" />
			745	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
			746	<xs:attribute name="tier" type="xs:string" default="2" />
			747	</xs:extension>
			748	</xs:simpleContent>
			749	</xs:complexType>
			750	</xs:element>
		-+	752	<xs:simpleType name="yes_or_no_unknown">
			753	<xs:restriction base="xs:string">
			754	<xs:enumeration value="YES" />
			755	<xs:enumeration value="NO" />
			756	<xs:enumeration value="" />
			757	</xs:restriction>
			758	</xs:simpleType>

   
File: TCGA_BCR.UCEC_Clinical_FollowUp_v1.7.xsd  

1	<?xml version="1.0" encoding="utf-8" ?>	+-
3	<xs:schema elementFormDefault="qualified" version="2.5.0"	+-
4	xmlns:xs="http://www.w3.org/2001/XMLSchema"
5	xmlns:shared="http://tcga.nci/bcr/xml/clinical/shared/2.5"
6	xmlns:utility="http://tcga.nci/bcr/xml/utility/2.5"
7	xmlns:admin="http://tcga.nci/bcr/xml/administration/2.5"
8	xmlns:ucec_shared="http://tcga.nci/bcr/xml/clinical/ucec/shared/2.5"
9	xmlns="http://tcga.nci/bcr/xml/clinical/ucec/followup/2.5/1.7"
10	targetNamespace="http://tcga.nci/bcr/xml/clinical/ucec/followup/2.5/1.7"
11	xmlns:jaxb="http://java.sun.com/xml/ns/jaxb" jaxb:version="1.0" >
13	<xs:import schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/utility/2.5/TCGA_BCR.Utility.xsd" namespace="http://tcga.nci/bcr/xml/utility/2.5" />	+-
14	<xs:import schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/administration/2.5/TCGA_BCR.Administration.xsd" namespace="http://tcga.nci/bcr/xml/administration/2.5" />
15	<xs:import schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/shared/2.5/TCGA_BCR.Shared_Clinical_Elements.xsd" namespace="http://tcga.nci/bcr/xml/clinical/shared/2.5" />
16	<xs:import schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/ucec/shared/2.5/TCGA_BCR.UCEC_Clinical_Shared_Datatypes.xsd" namespace="http://tcga.nci/bcr/xml/clinical/ucec/shared/2.5" />
17	<xs:annotation>
18	<xs:appinfo>
19	<jaxb:globalBindings generateIsSetMethod="true" />
20	<jaxb:schemaBindings>
21	<jaxb:package name="nci.tcga.bcr.xml.jaxb.clinical.ucec" />
22	</jaxb:schemaBindings>
23	</xs:appinfo>
24	</xs:annotation>
25	<xs:annotation>
26	<xs:documentation xml:lang="en">Schema to define the elements of the TCGA Clinical Data Follow-up Form within the UCEC study.</xs:documentation>
27	</xs:annotation>
28	<xs:element name="follow_up_v1.7">
29	<xs:complexType>
30	<xs:sequence>
31	<xs:element ref="shared:bcr_patient_barcode" />
32	<xs:element ref="shared:bcr_patient_uuid" />
34	<xs:element ref="ucec_shared:horm_ther" />	+-
35	<xs:element ref="ucec_shared:birth_control_pill_history_usage_category" />
36	<xs:element ref="ucec_shared:prior_tamoxifen_administered_usage_category" />
37	<xs:element ref="ucec_shared:hypertension" />
38	<xs:element ref="ucec_shared:diabetes" />
39	<xs:element ref="ucec_shared:pregnancies" />
40	<xs:element ref="ucec_shared:colorectal_cancer" />
41	<xs:element ref="shared:radiation_therapy" />
42	<xs:element ref="shared:targeted_molecular_therapy" />
43	<xs:element ref="ucec_shared:primary_therapy_outcome_success" />
44	<xs:element ref="shared:vital_status">
45	<xs:annotation>
46	<xs:documentation xml:lang="en">
47	Data for the vital_status element is also asked on the
48	TCGA Clinical Data Form during initial enrollment within the UCEC study.
49	</xs:documentation>
50	</xs:annotation>
51	</xs:element>
52	<xs:element ref="shared:person_neoplasm_cancer_status">
53	<xs:annotation>
54	<xs:documentation xml:lang="en">
55	Data for the person_neoplasm_cancer_status element is also asked on the
56	TCGA Clinical Data Form during initial enrollment within the UCEC study.
57	</xs:documentation>
58	</xs:annotation>
59	</xs:element>
60	<xs:choice>
61	<xs:annotation>
62	<xs:documentation xml:lang="en">
63	Data for the DATE_of_last_followup elements are also asked on the
64	TCGA Clinical Data Form during initial enrollment within the UCEC study.
65	</xs:documentation>
66	</xs:annotation>
67	<xs:sequence>
68	<xs:element ref="shared:day_of_last_followup" />
69	<xs:element ref="shared:month_of_last_followup" />
70	<xs:element ref="shared:year_of_last_followup" />
71	</xs:sequence>
72	<xs:element ref="shared:days_to_last_followup" />
73	</xs:choice>
74	<xs:choice>
75	<xs:annotation>
76	<xs:documentation xml:lang="en">
77	Data for the DATE_of_last_known_alive element is also asked on the
78	TCGA Clinical Data Form during initial enrollment within the UCEC study.
80	DEPRECATED:	+-
81	This question is no longer asked on the TCGA Clinical Data Follow-up Form (starting with v2.0)
82	within the UCEC study.
83	</xs:documentation>
84	</xs:annotation>
85	<xs:sequence>
86	<xs:element ref="shared:day_of_last_known_alive" />
87	<xs:element ref="shared:month_of_last_known_alive" />
88	<xs:element ref="shared:year_of_last_known_alive" />
89	</xs:sequence>
90	<xs:element ref="shared:days_to_last_known_alive" />
91	</xs:choice>
92	<xs:choice>
93	<xs:annotation>
94	<xs:documentation xml:lang="en">
95	Data for the DATE_of_death elements are also asked on the
96	TCGA Clinical Data Form during initial enrollment within the BRCA study.
97	</xs:documentation>
98	</xs:annotation>
99	<xs:sequence>
100	<xs:element ref="shared:day_of_death" />
101	<xs:element ref="shared:month_of_death" />
102	<xs:element ref="shared:year_of_death" />
103	</xs:sequence>
104	<xs:element ref="shared:days_to_death" />
105	</xs:choice>
106	<xs:choice>
107	<xs:sequence>
108	<xs:element ref="shared:day_of_new_tumor_event_after_initial_treatment" />
109	<xs:element ref="shared:month_of_new_tumor_event_after_initial_treatment" />
110	<xs:element ref="shared:year_of_new_tumor_event_after_initial_treatment" />
111	</xs:sequence>
112	<xs:element ref="shared:days_to_new_tumor_event_after_initial_treatment" />
113	</xs:choice>
115	<xs:element ref="shared:additional_surgery_locoregional_procedure" />	+-
117	<xs:choice>	+-
118	<xs:sequence>
119	<xs:element ref="shared:day_of_additional_surgery_metastatic_procedure" />
120	<xs:element ref="shared:month_of_additional_surgery_metastatic_procedure" />
121	<xs:element ref="shared:year_of_additional_surgery_metastatic_procedure" />
122	</xs:sequence>
123	<xs:element ref="shared:days_to_additional_surgery_metastatic_procedure" />
124	</xs:choice>
125	<xs:element ref="ucec_shared:recurrence_second_surgery_neoplasm_surgical_procedure_name" />
126	<xs:element ref="ucec_shared:recurrence_second_surgery_neoplasm_surgical_procedure_name_other">
127	<xs:annotation><xs:documentation>
128	Data for the recurrence_second_surgery_neoplasm_surgical_procedure_name_other element is *only* asked on the
129	TCGA Clinical Data Follow-up Form within the UCEC study, *and only* when
130	an answer of 'Other (please specify)' is provided for recurrence_second_surgery_neoplasm_surgical_procedure_name.
131	</xs:documentation></xs:annotation>
132	</xs:element>
133	<xs:element ref="shared:followup_met_assessment_outcome_success_margin_status" />
134	<xs:element ref="shared:additional_radiation_therapy" />
135	<xs:element ref="shared:additional_pharmaceutical_therapy" />
136	<xs:element ref="ucec_shared:additional_treatment_completion_success_outcome" />
138	<xs:choice>	+-
139	<xs:annotation>
140	<xs:documentation>
141	Date the interviewer originally completed the corresponding TCGA Clinical Data Form.
142	If modifications are made after the form is marked complete, this date should not change.
143	</xs:documentation>
144	</xs:annotation>
145	<xs:sequence>
146	<xs:element ref="shared:day_of_form_completion" />
147	<xs:element ref="shared:month_of_form_completion" />
148	<xs:element ref="shared:year_of_form_completion" />
149	</xs:sequence>
150	<xs:element ref="shared:days_to_form_completion" />
151	</xs:choice>
152	</xs:sequence>
153	<xs:attribute name="version" type="xs:string" default="1.7" use="optional"/>
154	</xs:complexType>
155	</xs:element>
156	</xs:schema>

   
File: TCGA_BCR.UCEC_Clinical_FollowUp_v2.0.xsd  

1	<?xml version="1.0" encoding="utf-8" ?>	+-
2	<xs:schema elementFormDefault="qualified" version="2.5.0"
3	xmlns:xs="http://www.w3.org/2001/XMLSchema"
4	xmlns:utility="http://tcga.nci/bcr/xml/utility/2.5"
5	xmlns:admin="http://tcga.nci/bcr/xml/administration/2.5"
6	xmlns:shared="http://tcga.nci/bcr/xml/clinical/shared/2.5"
7	xmlns:ucec_shared="http://tcga.nci/bcr/xml/clinical/ucec/shared/2.5"
8	xmlns="http://tcga.nci/bcr/xml/clinical/ucec/followup/2.5/2.0"
9	targetNamespace="http://tcga.nci/bcr/xml/clinical/ucec/followup/2.5/2.0"
10	xmlns:jaxb="http://java.sun.com/xml/ns/jaxb" jaxb:version="1.0">
12	<xs:import namespace="http://tcga.nci/bcr/xml/utility/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/utility/2.5/TCGA_BCR.Utility.xsd" />	+-
13	<xs:import namespace="http://tcga.nci/bcr/xml/administration/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/administration/2.5/TCGA_BCR.Administration.xsd" />
14	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/shared/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/shared/2.5/TCGA_BCR.Shared_Clinical_Elements.xsd" />
15	<xs:import namespace="http://tcga.nci/bcr/xml/clinical/ucec/shared/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/clinical/ucec/shared/2.5/TCGA_BCR.UCEC_Clinical_Shared_Datatypes.xsd" />
17	<xs:annotation>	+-
18	<xs:appinfo>
19	<jaxb:globalBindings generateIsSetMethod="true"/>
20	<jaxb:schemaBindings>
21	<jaxb:package name="nci.tcga.bcr.xml.jaxb.clinical.ucec"/>
22	</jaxb:schemaBindings>
23	</xs:appinfo>
24	</xs:annotation>
26	<xs:annotation>	+-
27	<xs:documentation xml:lang="en">Schema to define the elements of the TCGA clinical data follow-up form within the UCEC study.</xs:documentation>
28	</xs:annotation>
30	<xs:element name="follow_up_v2.0">	+-
31	<xs:complexType>
32	<xs:sequence>
33	<xs:element ref="shared:bcr_patient_barcode" />
34	<xs:element ref="shared:bcr_patient_uuid" />
37	<xs:element ref="shared:followup_case_report_form_submission_reason">	+-
38	<xs:annotation>
39	<xs:documentation xml:lang="en">
40	NEW question that was added on the TCGA Clinical Data Follow-up (starting with v2.0) Form within the UCEC study.
41	</xs:documentation>
42	</xs:annotation>
43	</xs:element>
44	<xs:element ref="shared:radiation_therapy" />
45	<xs:element ref="shared:targeted_molecular_therapy" />
46	<xs:element ref="ucec_shared:horm_ther" />
47	<xs:element ref="ucec_shared:birth_control_pill_history_usage_category" />
48	<xs:element ref="ucec_shared:prior_tamoxifen_administered_usage_category" />
49	<xs:element ref="ucec_shared:hypertension" />
50	<xs:element ref="ucec_shared:diabetes" />
51	<xs:element ref="ucec_shared:pregnancies" />
52	<xs:element ref="ucec_shared:colorectal_cancer" />
53	<xs:element ref="shared:vital_status">
54	<xs:annotation>
55	<xs:documentation xml:lang="en">
56	Data for the vital_status element is also asked on the
57	TCGA Clinical Data Form during initial enrollment within the UCEC study.
58	</xs:documentation>
59	</xs:annotation>
60	</xs:element>
61	<xs:choice>
62	<xs:annotation>
63	<xs:documentation xml:lang="en">
64	Data for the DATE_of_last_followup elements are also asked on the
65	TCGA Clinical Data Form during initial enrollment within the UCEC study.
66	</xs:documentation>
67	</xs:annotation>
68	<xs:sequence>
69	<xs:element ref="shared:day_of_last_followup" />
70	<xs:element ref="shared:month_of_last_followup" />
71	<xs:element ref="shared:year_of_last_followup" />
72	</xs:sequence>
73	<xs:element ref="shared:days_to_last_followup" />
74	</xs:choice>
75	<xs:choice>
76	<xs:annotation>
77	<xs:documentation xml:lang="en">
78	Data for the DATE_of_death elements are also asked on the
79	TCGA Clinical Data Form during initial enrollment within the BRCA study.
80	</xs:documentation>
81	</xs:annotation>
82	<xs:sequence>
83	<xs:element ref="shared:day_of_death" />
84	<xs:element ref="shared:month_of_death" />
85	<xs:element ref="shared:year_of_death" />
86	</xs:sequence>
87	<xs:element ref="shared:days_to_death" />
88	</xs:choice>
89	<xs:element ref="shared:person_neoplasm_cancer_status">
90	<xs:annotation>
91	<xs:documentation xml:lang="en">
92	Data for the person_neoplasm_cancer_status element is also asked on the
93	TCGA Clinical Data Form during initial enrollment within the UCEC study.
94	</xs:documentation>
95	</xs:annotation>
96	</xs:element>
97	<xs:element ref="ucec_shared:primary_therapy_outcome_success" />
98	<xs:element ref="ucec_shared:additional_treatment_completion_success_outcome" />
100	<xs:element ref="shared:new_tumor_event_after_initial_treatment">	+-
101	<xs:annotation>
102	<xs:documentation xml:lang="en">
103	NEW question that was added on the TCGA Clinical Data Follow-up (starting with v2.0) Form within the UCEC study.
104	</xs:documentation>
105	</xs:annotation>
106	</xs:element>
107	<xs:choice>
108	<xs:sequence>
109	<xs:element ref="shared:day_of_new_tumor_event_after_initial_treatment" />
110	<xs:element ref="shared:month_of_new_tumor_event_after_initial_treatment" />
111	<xs:element ref="shared:year_of_new_tumor_event_after_initial_treatment" />
112	</xs:sequence>
113	<xs:element ref="shared:days_to_new_tumor_event_after_initial_treatment" />
114	</xs:choice>
116	<xs:element ref="ucec_shared:new_neoplasm_event_occurrence_anatomic_site">	+-
117	<xs:annotation>
118	<xs:documentation xml:lang="en">
119	NEW question that was added on the TCGA Clinical Data Follow-up (starting with v2.0) Form within the UCEC study.
120	</xs:documentation>
121	</xs:annotation>
122	</xs:element>
123	<xs:element ref="ucec_shared:new_neoplasm_occurrence_anatomic_site_text">
124	<xs:annotation>
125	<xs:documentation xml:lang="en">
126	NEW question that was added on the TCGA Clinical Data Follow-up (starting with v2.0) Form within the UCEC study.
128	Data for the new_neoplasm_occurrence_anatomic_site_text element is *only* asked on the	+-
129	TCGA Clinical Data Follow-up (starting with v2.0) Form within the UCEC study, *and only* when
130	an answer of 'Other (please specify)' is provided for new_neoplasm_event_occurrence_anatomic_site.
131	</xs:documentation>
132	</xs:annotation>
133	</xs:element>
134	<xs:element ref="shared:new_neoplasm_event_type">
135	<xs:annotation>
136	<xs:documentation xml:lang="en">
137	NEW question that was added on the TCGA Clinical Data Follow-up (starting with v2.0) Form within the UCEC study.
138	</xs:documentation>
139	</xs:annotation>
140	</xs:element>
141	<xs:element ref="shared:additional_surgery_locoregional_procedure" />
142	<xs:choice>
143	<xs:sequence>
144	<xs:element ref="shared:day_of_additional_surgery_metastatic_procedure" />
145	<xs:element ref="shared:month_of_additional_surgery_metastatic_procedure" />
146	<xs:element ref="shared:year_of_additional_surgery_metastatic_procedure" />
147	</xs:sequence>
148	<xs:element ref="shared:days_to_additional_surgery_metastatic_procedure" />
149	</xs:choice>
150	<xs:element ref="ucec_shared:recurrence_second_surgery_neoplasm_surgical_procedure_name" />
151	<xs:element ref="ucec_shared:recurrence_second_surgery_neoplasm_surgical_procedure_name_other">
152	<xs:annotation><xs:documentation>
153	Data for the recurrence_second_surgery_neoplasm_surgical_procedure_name_other element is *only* asked on the
154	TCGA Clinical Data Follow-up Form within the UCEC study, *and only* when
155	an answer of 'Other (please specify)' is provided for recurrence_second_surgery_neoplasm_surgical_procedure_name.
156	</xs:documentation></xs:annotation>
157	</xs:element>
158	<xs:element ref="shared:followup_met_assessment_outcome_success_margin_status" />
159	<xs:element ref="shared:additional_radiation_therapy" />
160	<xs:element ref="shared:additional_pharmaceutical_therapy" />
162	<xs:choice>	+-
163	<xs:annotation>
164	<xs:documentation>
165	Date the interviewer originally completed the corresponding TCGA Clinical Data Form.
166	If modifications are made after the form is marked complete, this date should not change.
167	</xs:documentation>
168	</xs:annotation>
169	<xs:sequence>
170	<xs:element ref="shared:day_of_form_completion" />
171	<xs:element ref="shared:month_of_form_completion" />
172	<xs:element ref="shared:year_of_form_completion" />
173	</xs:sequence>
174	<xs:element ref="shared:days_to_form_completion" />
175	</xs:choice>
176	</xs:sequence>
177	<xs:attribute name="version" type="xs:string" default="2.0" use="optional"/>
178	</xs:complexType>
179	</xs:element>
180	</xs:schema>

   
File: TCGA_BCR.UCEC_Clinical_Shared_Datatypes.xsd  

1	<?xml version="1.0" encoding="utf-8" ?>	+-
4	<xs:schema elementFormDefault="qualified" version="2.5.0"	+-
5	xmlns:xs="http://www.w3.org/2001/XMLSchema"
6	xmlns:utility="http://tcga.nci/bcr/xml/utility/2.5"
7	xmlns="http://tcga.nci/bcr/xml/clinical/ucec/shared/2.5"
8	targetNamespace="http://tcga.nci/bcr/xml/clinical/ucec/shared/2.5">
10	<xs:import namespace="http://tcga.nci/bcr/xml/utility/2.5" schemaLocation="http://tcga-data.nci.nih.gov/docs/xsd/BCR/tcga.nci/bcr/xml/utility/2.5/TCGA_BCR.Utility.xsd" />	+-
13	<xs:element name="horm_ther" nillable="true">	+-
14	<xs:complexType mixed="true">
15	<xs:simpleContent>
16	<xs:restriction base="utility:clinical_res_attributes">
17	<xs:enumeration value="" />
18	<xs:enumeration value="Yes, I am currently taking menopausal hormone therapy." />
19	<xs:enumeration value="Yes, I have taken menopausal hormone therapy in the past, but no longer do." />
20	<xs:enumeration value="No, I have never taken menopausal hormone therapy." />
21	<xs:attribute name="cde" type="xs:string" default="3012813" />
22	<xs:attribute name="xsd_ver" type="xs:string" default="2.4" />
23	<xs:attribute name="tier" type="xs:string" default="2" />
24	</xs:restriction>
25	</xs:simpleContent>
26	</xs:complexType>
27	</xs:element>
29	<xs:element name="birth_control_pill_history_usage_category" nillable="true">	+-
30	<xs:complexType mixed="true">
31	<xs:simpleContent>
32	<xs:restriction base="utility:clinical_res_attributes">
33	<xs:enumeration value="" />
34	<xs:enumeration value="Current User" />
35	<xs:enumeration value="Former User" />
36	<xs:enumeration value="Never Used" />
37	<xs:enumeration value="Unknown" />
38	<xs:attribute name="cde" type="xs:string" default="3104217" />
39	<xs:attribute name="xsd_ver" type="xs:string" default="2.4" />
40	<xs:attribute name="tier" type="xs:string" default="2" />
41	</xs:restriction>
42	</xs:simpleContent>
43	</xs:complexType>
44	</xs:element>
46	<xs:element name="prior_tamoxifen_administered_usage_category" nillable="true">	+-
47	<xs:complexType mixed="true">
48	<xs:simpleContent>
49	<xs:restriction base="utility:clinical_res_attributes">
50	<xs:enumeration value="" />
51	<xs:enumeration value="Current User" />
52	<xs:enumeration value="Former User" />
53	<xs:enumeration value="Never Used" />
54	<xs:attribute name="cde" type="xs:string" default="3104234" />
55	<xs:attribute name="xsd_ver" type="xs:string" default="2.4" />
56	<xs:attribute name="tier" type="xs:string" default="2" />
57	</xs:restriction>
58	</xs:simpleContent>
59	</xs:complexType>
60	</xs:element>
62	<xs:element name="hypertension" nillable="true">	+-
63	<xs:complexType>
64	<xs:simpleContent>
65	<xs:extension base="utility:yes_or_no">
66	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
67	<xs:attribute name="cde" type="xs:string" default="2183378" />
68	<xs:attribute name="xsd_ver" type="xs:string" default="2.4" />
69	<xs:attribute name="tier" type="xs:string" default="2" />
70	</xs:extension>
71	</xs:simpleContent>
72	</xs:complexType>
73	</xs:element>
75	<xs:element name="diabetes" nillable="true">	+-
76	<xs:complexType>
77	<xs:simpleContent>
78	<xs:extension base="utility:yes_or_no">
79	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
80	<xs:attribute name="cde" type="xs:string" default="2716085" />
81	<xs:attribute name="xsd_ver" type="xs:string" default="2.4" />
82	<xs:attribute name="tier" type="xs:string" default="2" />
83	</xs:extension>
84	</xs:simpleContent>
85	</xs:complexType>
86	</xs:element>
88	<xs:element name="pregnancies" nillable="true">	+-
89	<xs:complexType mixed="true">
90	<xs:simpleContent>
91	<xs:restriction base="utility:clinical_res_attributes">
92	<xs:enumeration value="" />
93	<xs:enumeration value="0" />
94	<xs:enumeration value="1" />
95	<xs:enumeration value="2" />
96	<xs:enumeration value="3" />
97	<xs:enumeration value="4+" />
98	<xs:attribute name="cde" type="xs:string" default="3012512" />
99	<xs:attribute name="xsd_ver" type="xs:string" default="2.4" />
100	<xs:attribute name="tier" type="xs:string" default="2" />
101	</xs:restriction>
102	</xs:simpleContent>
103	</xs:complexType>
104	</xs:element>
106	<xs:element name="colorectal_cancer" nillable="true">	+-
107	<xs:complexType>
108	<xs:simpleContent>
109	<xs:extension base="utility:yes_or_no">
110	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
111	<xs:attribute name="cde" type="xs:string" default="2684753" />
112	<xs:attribute name="xsd_ver" type="xs:string" default="2.4" />
113	<xs:attribute name="tier" type="xs:string" default="2" />
114	</xs:extension>
115	</xs:simpleContent>
116	</xs:complexType>
117	</xs:element>
119	<xs:element name="primary_therapy_outcome_success" nillable="true">	+-
120	<xs:complexType>
121	<xs:simpleContent>
122	<xs:restriction base="utility:clinical_res_attributes">
123	<xs:enumeration value="" />
124	<xs:enumeration value="Unknown" />
125	<xs:enumeration value="Not Applicable" />
126	<xs:enumeration value="Persistent Disease" />
127	<xs:enumeration value="Progressive Disease" />
128	<xs:enumeration value="Stable Disease" />
129	<xs:enumeration value="Partial Response" />
130	<xs:enumeration value="Complete Response" />
131	<xs:attribute name="cde" type="xs:string" default="2786727" />
132	<xs:attribute name="xsd_ver" type="xs:string" default="2.4" />
133	<xs:attribute name="tier" type="xs:string" default="2" />
134	</xs:restriction>
135	</xs:simpleContent>
136	</xs:complexType>
137	</xs:element>
139	<xs:element name="recurrence_second_surgery_neoplasm_surgical_procedure_name" nillable="true">	+-
140	<xs:complexType mixed="true">
141	<xs:simpleContent>
142	<xs:restriction base="utility:clinical_res_attributes">
143	<xs:enumeration value="" />
144	<xs:enumeration value="Excisional Biopsy" />
145	<xs:enumeration value="Incisional Biopsy" />
146	<xs:enumeration value="Surgical Resection" />
147	<xs:enumeration value="Other Method, Specify Below" />
148	<xs:attribute name="cde" type="xs:string" default="3125097" />
149	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
150	<xs:attribute name="tier" type="xs:string" default="2" />
151	</xs:restriction>
152	</xs:simpleContent>
153	</xs:complexType>
154	</xs:element>
156	<xs:element name="recurrence_second_surgery_neoplasm_surgical_procedure_name_other" nillable="true">	+-
157	<xs:complexType>
158	<xs:simpleContent>
159	<xs:extension base="xs:string">
160	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
161	<xs:attribute name="cde" type="xs:string" default="3125102" />
162	<xs:attribute name="xsd_ver" type="xs:string" default="2.3" />
163	<xs:attribute name="tier" type="xs:string" default="2" />
164	</xs:extension>
165	</xs:simpleContent>
166	</xs:complexType>
167	</xs:element>
169	<xs:element name="additional_treatment_completion_success_outcome" nillable="true">	+-
170	<xs:complexType mixed="true">
171	<xs:simpleContent>
172	<xs:restriction base="utility:clinical_res_attributes">
173	<xs:enumeration value="" />
174	<xs:enumeration value="Progressive Disease" />
175	<xs:enumeration value="Stable Disease" />
176	<xs:enumeration value="Partial Response" />
177	<xs:enumeration value="Complete Response" />
178	<xs:attribute name="cde" type="xs:string" default="3033278" />
179	<xs:attribute name="xsd_ver" type="xs:string" default="2.5" />
180	<xs:attribute name="tier" type="xs:string" default="1" />
181	</xs:restriction>
182	</xs:simpleContent>
183	</xs:complexType>
184	</xs:element>
186	<xs:element name="new_neoplasm_event_occurrence_anatomic_site" nillable="true">	+-
187	<xs:complexType mixed="true">
188	<xs:simpleContent>
189	<xs:restriction base="utility:clinical_res_attributes">
190	<xs:enumeration value="" />
191	<xs:enumeration value="Lung" />
192	<xs:enumeration value="Liver" />
193	<xs:enumeration value="Bone" />
194	<xs:enumeration value="Brain" />
195	<xs:enumeration value="Other, specify" />
196	<xs:attribute name="cde" type="xs:string" default="3108271" />
197	<xs:attribute name="xsd_ver" type="xs:string" default="2.5" />
198	<xs:attribute name="tier" type="xs:string" default="2" />
199	</xs:restriction>
200	</xs:simpleContent>
201	</xs:complexType>
202	</xs:element>
204	<xs:element name="new_neoplasm_occurrence_anatomic_site_text" nillable="true">	+-
205	<xs:complexType>
206	<xs:simpleContent>
207	<xs:extension base="xs:string">
208	<xs:attributeGroup ref="utility:common_ext_attribute_group" />
209	<xs:attribute name="cde" type="xs:string" default="3128033" />
210	<xs:attribute name="xsd_ver" type="xs:string" default="2.5" />
211	<xs:attribute name="tier" type="xs:string" default="2" />
212	</xs:extension>
213	</xs:simpleContent>
214	</xs:complexType>
215	</xs:element>
217	</xs:schema>	+-

   
File: TCGA_BCR.Utility.xsd  

4	<xs:schema elementFormDefault="qualified" version="2.5.0"	<>	4	<xs:schema elementFormDefault="qualified" version="2.4.4"
6	xmlns="http://tcga.nci/bcr/xml/utility/2.5"	<>	6	xmlns="http://tcga.nci/bcr/xml/utility/2.4"
7	targetNamespace="http://tcga.nci/bcr/xml/utility/2.5">		7	targetNamespace="http://tcga.nci/bcr/xml/utility/2.4">
13	<xs:attribute name="preferred_name" type="xs:string" use="optional" default=""/>	+-
14	<xs:attribute name="display_order" type="xs:integer" use="optional" default="9999"/>
23	<xs:attribute name="units" type="xs:string" use="optional" default="" />	+-
30	<xs:attribute name="preferred_name" type="xs:string" use="optional" default=""/>	+-
31	<xs:attribute name="display_order" type="xs:integer" use="optional" default="9999"/>
57	</xs:simpleType>	+-
59	<xs:simpleType>	+-
60	<xs:restriction base="xs:string">
61	<xs:enumeration value=""/>
62	</xs:restriction>
63	</xs:simpleType>
64	</xs:union>
65	</xs:simpleType>
67	<xs:simpleType name="integer_or_null">	+-
68	<xs:union memberTypes="xs:integer">
69	<xs:simpleType>
70	<xs:restriction base="xs:integer" />